Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | hypothetical protein | 0.038 | 0.2971 | 1 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.001 | 0.0029 | 0.0013 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.0029 | 0.0013 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0029 | 0.0003 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0149 | 0.0421 |
Trichomonas vaginalis | MYB72, putative | 0.001 | 0.0027 | 0.0148 |
Echinococcus granulosus | glycoprotein Antigen 5 | 0.038 | 0.2971 | 1 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.001 | 0.0029 | 0.005 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.001 | 0.0029 | 0.0003 |
Loa Loa (eye worm) | hypothetical protein | 0.038 | 0.2971 | 1 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.001 | 0.0029 | 0.005 |
Brugia malayi | Trypsin family protein | 0.038 | 0.2971 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.001 | 0.0029 | 0.0013 |
Schistosoma mansoni | hypothetical protein | 0.0011 | 0.0038 | 0.0083 |
Onchocerca volvulus | 0.038 | 0.2971 | 1 | |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0013 | 0.0053 | 0.0091 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.001 | 0.0029 | 0.005 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0149 | 0.4894 |
Plasmodium vivax | glutathione reductase, putative | 0.0038 | 0.0249 | 1 |
Trichomonas vaginalis | r2r3-MYB transcription factor, putative | 0.001 | 0.0028 | 0.015 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0013 | 0.0053 | 1 |
Trichomonas vaginalis | MYB3r3, putative | 0.001 | 0.0027 | 0.0148 |
Trichomonas vaginalis | MYB, putative | 0.001 | 0.0028 | 0.015 |
Echinococcus multilocularis | glycoprotein Antigen 5 | 0.038 | 0.2971 | 1 |
Entamoeba histolytica | myb-like DNA-binding domain containing protein | 0.001 | 0.0027 | 0.5 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.038 | 0.2971 | 1 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0149 | 0.4894 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.003 | 0.0191 | 0.0598 |
Echinococcus granulosus | enteropeptidase | 0.038 | 0.2971 | 1 |
Brugia malayi | Trypsin family protein | 0.038 | 0.2971 | 1 |
Echinococcus granulosus | Mastin | 0.038 | 0.2971 | 1 |
Echinococcus multilocularis | cpg binding protein | 0.003 | 0.019 | 0.0595 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.038 | 0.2971 | 1 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.038 | 0.2971 | 1 |
Brugia malayi | Pre-SET motif family protein | 0.003 | 0.0191 | 0.0563 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.038 | 0.2971 | 1 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0086 | 0.0635 | 0.0819 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0013 | 0.0053 | 0.0094 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0062 | 0.0442 | 0.1447 |
Trichomonas vaginalis | r2r3-MYB transcription factor, putative | 0.001 | 0.0027 | 0.0148 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.0029 | 0.0013 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0029 | 0.0003 |
Toxoplasma gondii | shikimate dehydrogenase substrate binding domain-containing protein | 0.0356 | 0.2782 | 1 |
Loa Loa (eye worm) | trypsin family protein | 0.038 | 0.2971 | 1 |
Brugia malayi | hypothetical protein | 0.0016 | 0.0078 | 0.0179 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.019 | 0.0595 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.019 | 0.0595 |
Treponema pallidum | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | 0.1264 | 1 | 1 |
Trichomonas vaginalis | r2r3-MYB transcription factor, putative | 0.001 | 0.0027 | 0.0148 |
Brugia malayi | steroid hormone receptor | 0.001 | 0.0029 | 0.0013 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.001 | 0.0029 | 0.0003 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.001 | 0.0029 | 0.0013 |
Trichomonas vaginalis | r2r3-MYB transcription factor, putative | 0.001 | 0.0027 | 0.0148 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0191 | 0.0598 |
Onchocerca volvulus | 0.0238 | 0.1838 | 0.6149 | |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0038 | 0.0253 | 0.081 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.0029 | 0.005 |
Plasmodium falciparum | thioredoxin reductase | 0.0038 | 0.0249 | 1 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0038 | 0.0249 | 0.0276 |
Onchocerca volvulus | 0.003 | 0.0191 | 0.0551 | |
Leishmania major | trypanothione reductase | 0.0038 | 0.0249 | 1 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.001 | 0.0029 | 0.005 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0029 | 0.0177 | 0.0506 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0191 | 0.0554 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.0029 | 0.005 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0191 | 0.0598 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.003 | 0.0191 | 0.0598 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.001 | 0.0029 | 0.005 |
Loa Loa (eye worm) | steroid hormone receptor | 0.001 | 0.0029 | 0.0003 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.0029 | 0.005 |
Onchocerca volvulus | 0.038 | 0.2971 | 1 | |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.001 | 0.0029 | 0.005 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0013 | 0.0053 | 0.0131 |
Schistosoma mansoni | aminopeptidase PILS (M01 family) | 0.038 | 0.2971 | 1 |
Mycobacterium ulcerans | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | 0.1264 | 1 | 1 |
Toxoplasma gondii | thioredoxin reductase | 0.0038 | 0.0249 | 0.0805 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0013 | 0.0053 | 0.0286 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0086 | 0.0635 | 0.0819 |
Trichomonas vaginalis | r2r3-MYB transcription factor, putative | 0.001 | 0.0027 | 0.0148 |
Echinococcus multilocularis | enteropeptidase | 0.038 | 0.2971 | 1 |
Echinococcus multilocularis | FTZ F1 alpha | 0.001 | 0.0029 | 0.005 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0096 | 0.0711 | 0.0926 |
Brugia malayi | nuclear receptor NHR-88 | 0.001 | 0.0029 | 0.0013 |
Echinococcus multilocularis | Mastin | 0.038 | 0.2971 | 1 |
Trichomonas vaginalis | set domain proteins, putative | 0.0238 | 0.1838 | 1 |
Onchocerca volvulus | 0.038 | 0.2971 | 1 | |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.001 | 0.0028 | 0.0047 |
Schistosoma mansoni | hypothetical protein | 0.038 | 0.2971 | 1 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.001 | 0.0029 | 0.0003 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0038 | 0.0249 | 0.0753 |
Echinococcus granulosus | cpg binding protein | 0.003 | 0.019 | 0.0595 |
Entamoeba histolytica | myb-like DNA-binding domain containing protein | 0.001 | 0.0027 | 0.5 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.0029 | 0.005 |
Loa Loa (eye worm) | hypothetical protein | 0.038 | 0.2971 | 1 |
Plasmodium falciparum | glutathione reductase | 0.0038 | 0.0249 | 1 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0029 | 0.0177 | 0.0552 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0011 | 0.0038 | 0.0083 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0011 | 0.0038 | 0.0083 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.003 | 0.0191 | 0.0598 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.001 | 0.0029 | 0.0013 |
Brugia malayi | Chymotrypsin-like protease CTRL-1 precursor | 0.038 | 0.2971 | 1 |
Brugia malayi | ecdysteroid receptor | 0.001 | 0.0029 | 0.0013 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.0029 | 0.005 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0013 | 0.0053 | 0.0131 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.001 | 0.0029 | 0.0013 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.0177 | 0.0551 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.038 | 0.2971 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.0029 | 0.0013 |
Trichomonas vaginalis | pc-MYB2, putative | 0.001 | 0.0027 | 0.0148 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.001 | 0.0029 | 0.005 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.0029 | 0.005 |
Trichomonas vaginalis | r2r3-MYB transcription factor, putative | 0.001 | 0.0027 | 0.0148 |
Loa Loa (eye worm) | hypothetical protein | 0.038 | 0.2971 | 1 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.001 | 0.0029 | 0.005 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.001 | 0.0029 | 0.0003 |
Loa Loa (eye worm) | hypothetical protein | 0.038 | 0.2971 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.001 | 0.0029 | 0.0003 |
Trichomonas vaginalis | r2r3-MYB transcription factor, putative | 0.001 | 0.0027 | 0.0148 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.0029 | 0.0013 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0029 | 0.0003 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.0029 | 0.005 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.038 | 0.2971 | 1 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.001 | 0.0029 | 0.005 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.001 | 0.0029 | 0.005 |
Schistosoma mansoni | coup transcription factor | 0.001 | 0.0029 | 0.005 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.038 | 0.2971 | 1 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.001 | 0.0029 | 0.005 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.001 | 0.0029 | 0.0013 |
Brugia malayi | nuclear hormone receptor | 0.001 | 0.0029 | 0.0013 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0038 | 0.0253 | 0.081 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0086 | 0.0635 | 0.0819 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0013 | 0.0053 | 0.0286 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.038 | 0.2971 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.038 | 0.2971 | 1 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.001 | 0.0029 | 0.005 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.001 | 0.0029 | 0.005 |
Mycobacterium ulcerans | 3-phosphoshikimate 1-carboxyvinyltransferase | 0.0356 | 0.2782 | 0.2744 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.001 | 0.0029 | 0.005 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.001 | 0.0027 | 0.0007 |
Trypanosoma brucei | trypanothione reductase | 0.0038 | 0.0249 | 1 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0096 | 0.0711 | 0.0117 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0096 | 0.0711 | 0.0926 |
Brugia malayi | Trypsin family protein | 0.038 | 0.2971 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.001 | 0.0029 | 0.0013 |
Onchocerca volvulus | 0.038 | 0.2971 | 1 | |
Echinococcus multilocularis | Peptidase S1 S6, chymotrypsin Hap | 0.038 | 0.2971 | 1 |
Onchocerca volvulus | 0.0029 | 0.0177 | 0.0503 | |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0086 | 0.0635 | 0.0819 |
Echinococcus granulosus | subfamily S1A unassigned peptidase S01 family | 0.038 | 0.2971 | 1 |
Echinococcus granulosus | Peptidase S1 S6 chymotrypsin Hap | 0.038 | 0.2971 | 1 |
Brugia malayi | Trypsin-like protease protein 5 | 0.038 | 0.2971 | 1 |
Loa Loa (eye worm) | glutathione reductase | 0.0038 | 0.0249 | 0.0753 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.001 | 0.0029 | 0.005 |
Wolbachia endosymbiont of Brugia malayi | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | 0.1264 | 1 | 1 |
Echinococcus granulosus | transmembrane protease serine 3 | 0.038 | 0.2971 | 1 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0038 | 0.0249 | 1 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.038 | 0.2971 | 1 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.038 | 0.2971 | 1 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0025 | 0.0149 | 0.4894 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0149 | 0.4894 |
Mycobacterium ulcerans | hypothetical protein | 0.038 | 0.2971 | 0.2934 |
Echinococcus multilocularis | subfamily S1A unassigned peptidase (S01 family) | 0.038 | 0.2971 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.001 | 0.0029 | 0.005 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0029 | 0.0003 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0025 | 0.0149 | 0.044 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0209 | 0.1609 | 0.5373 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.0029 | 0.0013 |
Brugia malayi | Trypsin family protein | 0.038 | 0.2971 | 1 |
Echinococcus granulosus | FTZ F1 alpha | 0.001 | 0.0029 | 0.005 |
Onchocerca volvulus | 0.038 | 0.2971 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.038 | 0.2971 | 1 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.038 | 0.2971 | 1 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0025 | 0.0149 | 0.4894 |
Onchocerca volvulus | 0.038 | 0.2971 | 1 | |
Mycobacterium leprae | PROBABLE UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE MURA | 0.0908 | 0.7166 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0029 | 0.0003 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.001 | 0.0029 | 0.0003 |
Plasmodium vivax | SET domain protein, putative | 0.003 | 0.0191 | 0.7027 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0038 | 0.0249 | 1 |
Trichomonas vaginalis | pc-MYB2, putative | 0.001 | 0.0027 | 0.0148 |
Trichomonas vaginalis | C-MYB, putative | 0.001 | 0.0027 | 0.0148 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.001 | 0.0029 | 0.0013 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0013 | 0.0053 | 0.0091 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.038 | 0.2971 | 1 |
Trichomonas vaginalis | r2r3-MYB transcription factor, putative | 0.001 | 0.0028 | 0.015 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.001 | 0.0029 | 0.005 |
Loa Loa (eye worm) | hypothetical protein | 0.038 | 0.2971 | 1 |
Brugia malayi | Pre-SET motif family protein | 0.0209 | 0.1609 | 0.5377 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.001 | 0.0028 | 0.0047 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.001 | 0.0029 | 0.0013 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0029 | 0.0003 |
Entamoeba histolytica | myb-like DNA-binding domain containing protein | 0.001 | 0.0027 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0149 | 0.0411 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0149 | 0.4894 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.038 | 0.2971 | 1 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.038 | 0.2971 | 1 |
Mycobacterium leprae | probable 3-phosphoshikimate 1-carboxyvinyl transferase AroA (5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYNTHASE) (EPSP SYNTHASE) (EPSPS | 0.0356 | 0.2782 | 0.3287 |
Brugia malayi | CXXC zinc finger family protein | 0.0029 | 0.0177 | 0.0516 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.0029 | 0.0013 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0029 | 0.0003 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.038 | 0.2971 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.001 | 0.0029 | 0.0003 |
Chlamydia trachomatis | phosphoshikimate 1-carboxyl vinyltransferase | 0.0356 | 0.2782 | 0.2744 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.0029 | 0.005 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.038 | 0.2971 | 1 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.001 | 0.0029 | 0.005 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0096 | 0.0711 | 0.0926 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0086 | 0.0635 | 0.0819 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.003 | 0.0191 | 0.0593 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.0029 | 0.005 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.001 | 0.0029 | 0.0013 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0056 | 0.039 | 0.1316 |
Brugia malayi | glutathione reductase | 0.0038 | 0.0249 | 0.0761 |
Entamoeba histolytica | myb-like DNA-binding domain containing protein | 0.001 | 0.0027 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0029 | 0.0003 |
Trichomonas vaginalis | C-MYB, putative | 0.001 | 0.0027 | 0.0148 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.038 | 0.2971 | 1 |
Mycobacterium tuberculosis | Probable UDP-N-acetylglucosamine 1-carboxyvinyltransferase MurA | 0.0908 | 0.7166 | 1 |
Brugia malayi | hypothetical protein | 0.038 | 0.2971 | 1 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.038 | 0.2971 | 1 |
Entamoeba histolytica | myb-like DNA-binding domain containing protein | 0.001 | 0.0027 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.0025 | 0.0149 | 0.4894 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0013 | 0.0053 | 0.0131 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.0029 | 0.005 |
Echinococcus multilocularis | transmembrane protease serine 3 | 0.038 | 0.2971 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0191 | 0.0598 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.003 | 0.0191 | 0.0598 |
Mycobacterium tuberculosis | Probable reductase | 0.0086 | 0.0635 | 0.0819 |
Brugia malayi | Thioredoxin reductase | 0.0038 | 0.0249 | 0.0761 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (binding) | % | Inhibition of porcine pepsin | ChEMBL. | 3305946 |
Inhibition (binding) | = 35 % | The compound was tested for inhibition of human renal renin at the concentration of 10e-5 M (2:1 mixture of S:R diastereomers at the carbon bearing the hydroxyl group . | ChEMBL. | 3305946 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.