TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 217.267 | Formula: C12H15N3O
H donors: 2 H acceptors: 1 LogP: 0.42 Rotable bonds: 2
Rule of 5 violations (Lipinski): 1
SMILES: N[C@H]1C[C@H](C[C@@H]1Oc1ccc(cc1)C#N)N
InChi: 1S/C12H15N3O/c13-7-8-1-3-10(4-2-8)16-12-6-9(14)5-11(12)15/h1-4,9,11-12H,5-6,14-15H2/t9-,11+,12+/m1/s1
InChiKey: RLIYCDOWAWVRBI-USWWRNFRSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Echinococcus granulosus	neuropeptide s receptor	0.0056	0.9388	1
Loa Loa (eye worm)	neuropeptide F receptor	0.0056	0.9388	1
Echinococcus granulosus	neuropeptides capa receptor	0.0056	0.9388	1
Onchocerca volvulus		0.0056	0.9388	1
Onchocerca volvulus		0.0056	0.9388	1
Brugia malayi	CXXC zinc finger family protein	0.0028	0.4393	0.4102
Echinococcus granulosus	neuropeptide receptor A26	0.0056	0.9388	1
Loa Loa (eye worm)	gonadotropin-releasing hormone receptor 2	0.0056	0.9388	1
Schistosoma mansoni	cpg binding protein	0.003	0.4678	0.4619
Onchocerca volvulus		0.0056	0.9388	1
Echinococcus multilocularis	cpg binding protein	0.003	0.4678	0.462
Echinococcus multilocularis	cytoplasmic intermediate filament protein	0.0013	0.1658	0.117
Loa Loa (eye worm)	5-hydroxytryptamine 2C receptor	0.0056	0.9388	1
Echinococcus multilocularis	growth hormone secretagogue receptor type 1	0.0056	0.9388	1
Loa Loa (eye worm)	TYRA-2 protein	0.0056	0.9388	1
Loa Loa (eye worm)	hypothetical protein	0.0056	0.9388	1
Schistosoma mansoni	amine GPCR	0.0056	0.9388	0.9381
Brugia malayi	cytoplasmic intermediate filament protein	0.0014	0.1908	0.1167
Schistosoma mansoni	biogenic amine receptor	0.0056	0.9388	0.9381
Schistosoma mansoni	peptide (FMRFamide/neurokinin-3)-like receptor	0.0056	0.9388	0.9381
Schistosoma mansoni	neuropeptide receptor	0.0056	0.9388	0.9381
Echinococcus multilocularis	tachykinin peptides receptor 99D	0.0056	0.9388	1
Brugia malayi	G protein-coupled receptor F59B2.13	0.0056	0.9388	1
Brugia malayi	G protein-coupled receptor	0.0056	0.9388	1
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0056	0.9388	0.9381
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0056	0.9388	0.9381
Onchocerca volvulus		0.0056	0.9388	1
Echinococcus multilocularis	serotonin receptor	0.0056	0.9388	1
Trichomonas vaginalis	conserved hypothetical protein	0.0006	0.0525	1
Onchocerca volvulus	Dopamine\/Ecdysteroid receptor homolog	0.0056	0.9388	1
Loa Loa (eye worm)	hypothetical protein	0.0056	0.9388	1
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0056	0.9388	1
Echinococcus granulosus	allatostatin A receptor	0.0056	0.9388	1
Echinococcus granulosus	alpha 1A adrenergic receptor	0.0056	0.9388	1
Schistosoma mansoni	biogenic amine (octopamine/dopamine) receptor	0.0056	0.9388	0.9381
Echinococcus granulosus	tm gpcr rhodopsin	0.0056	0.9388	1
Schistosoma mansoni	neuropeptide F-like receptor	0.0056	0.9388	0.9381
Schistosoma mansoni	peptide (allatostatin)-like receptor	0.0056	0.9388	0.9381
Loa Loa (eye worm)	hypothetical protein	0.0012	0.1572	0.0749
Brugia malayi	larval opioid receptor	0.0056	0.9388	1
Loa Loa (eye worm)	hypothetical protein	0.0056	0.9388	1
Loa Loa (eye worm)	hypothetical protein	0.0056	0.9388	1
Echinococcus granulosus	lamin	0.0026	0.4088	0.3946
Loa Loa (eye worm)	hypothetical protein	0.0056	0.9388	1
Onchocerca volvulus		0.0056	0.9388	1
Echinococcus multilocularis	lamin dm0	0.0026	0.4088	0.3946
Schistosoma mansoni	histamine-responsive GPCR (AAF21638)	0.0056	0.9388	0.9381
Echinococcus granulosus	g protein coupled receptor	0.0056	0.9388	1
Loa Loa (eye worm)	hypothetical protein	0.0056	0.9388	1
Onchocerca volvulus		0.0056	0.9388	1
Brugia malayi	hypothetical protein	0.0056	0.9388	1
Schistosoma mansoni	neuropeptide f receptor 76f	0.0056	0.9388	0.9381
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0056	0.9388	0.9381
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0056	0.9388	0.9381
Echinococcus granulosus	cpg binding protein	0.003	0.4678	0.462
Echinococcus granulosus	rhodopsin orphan GPCR	0.0056	0.9388	1
Echinococcus multilocularis	dro:myosuppressin receptor	0.0056	0.9388	1
Brugia malayi	hypothetical protein	0.0056	0.9388	1
Echinococcus granulosus	7tm_1 domain containing protein	0.0056	0.9388	1
Loa Loa (eye worm)	hypothetical protein	0.0056	0.9388	1
Loa Loa (eye worm)	intermediate filament tail domain-containing protein	0.0026	0.4088	0.3727
Loa Loa (eye worm)	hypothetical protein	0.0056	0.9388	1
Schistosoma mansoni	neuropeptide receptor	0.0056	0.9388	0.9381
Brugia malayi	Dopamine receptor protein 1, putative (partial)	0.0056	0.9388	1
Echinococcus multilocularis	neuropeptide Y receptor	0.0056	0.9388	1
Loa Loa (eye worm)	hypothetical protein	0.0056	0.9388	1
Loa Loa (eye worm)	melatonin receptor type 1A	0.0056	0.9388	1
Echinococcus granulosus	dro:myosuppressin receptor	0.0056	0.9388	1
Schistosoma mansoni	hypothetical protein	0.0056	0.9388	0.9381
Onchocerca volvulus		0.0056	0.9388	1
Echinococcus granulosus	biogenic amine 5HT receptor	0.0056	0.9388	1
Loa Loa (eye worm)	hypothetical protein	0.0056	0.9388	1
Brugia malayi	Serotonin/octopamine receptor family protein 7	0.0056	0.9388	1
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0056	0.9388	1
Brugia malayi	putative neuropeptide receptor	0.0056	0.9388	1
Loa Loa (eye worm)	hypothetical protein	0.0056	0.9388	1
Brugia malayi	hypothetical protein	0.0056	0.9388	1
Schistosoma mansoni	cpg binding protein	0.003	0.4678	0.4619
Echinococcus granulosus	rhodopsin orphan GPCR	0.0056	0.9388	1
Brugia malayi	intermediate filament protein	0.0026	0.4088	0.3742
Trichomonas vaginalis	conserved hypothetical protein	0.0006	0.0525	1
Loa Loa (eye worm)	hypothetical protein	0.0056	0.9388	1
Echinococcus multilocularis	neuropeptide FF receptor 2	0.0056	0.9388	1
Loa Loa (eye worm)	hypothetical protein	0.0056	0.9388	1
Schistosoma mansoni	neuropeptide F-like receptor	0.0056	0.9388	0.9381
Trichomonas vaginalis	chromodomain helicase DNA binding protein, putative	0.0006	0.0525	1
Echinococcus multilocularis	serotonin receptor	0.0056	0.9388	1
Schistosoma mansoni	amine GPCR	0.0056	0.9388	0.9381
Loa Loa (eye worm)	hypothetical protein	0.0013	0.1658	0.0851
Schistosoma mansoni	opsin-like receptor	0.0056	0.9388	0.9381
Echinococcus granulosus	7TM GPCR rhodopsin	0.0056	0.9388	1
Trichomonas vaginalis	conserved hypothetical protein	0.0006	0.0525	1
Loa Loa (eye worm)	hypothetical protein	0.0056	0.9388	1
Brugia malayi	putative neuropeptide receptor NPR1	0.0056	0.9388	1
Echinococcus multilocularis	neuropeptides capa receptor	0.0056	0.9388	1
Echinococcus multilocularis	fmrfamide receptor	0.0056	0.9388	1
Loa Loa (eye worm)	hypothetical protein	0.0056	0.9388	1
Echinococcus multilocularis	peptide (allatostatin:somatostatin)	0.0056	0.9388	1
Loa Loa (eye worm)	hypothetical protein	0.0056	0.9388	1
Schistosoma mansoni	muscarinic acetylcholine (GAR) receptor	0.0056	0.9388	0.9381
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0056	0.9388	0.9381
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0056	0.9388	0.9381
Loa Loa (eye worm)	neuropeptide F receptor	0.0056	0.9388	1
Brugia malayi	Dopamine receptor	0.0056	0.9388	1
Loa Loa (eye worm)	G-protein-linked acetylcholine receptor protein 2	0.0056	0.9388	1
Schistosoma mansoni	hypothetical protein	0.0056	0.9388	0.9381
Trichomonas vaginalis	chromodomain helicase DNA binding protein, putative	0.0006	0.0525	1
Schistosoma mansoni	hypothetical protein	0.0056	0.9388	0.9381
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0056	0.9388	1
Brugia malayi	Unidentified vitellogenin-linked transcript protein 6, putative	0.0056	0.9388	1
Echinococcus multilocularis	biogenic amine (5HT) receptor	0.0056	0.9388	1
Echinococcus multilocularis	histone lysine N methyltransferase MLL3	0.0009	0.0939	0.0348
Echinococcus granulosus	peptide allatostatin:somatostatin	0.0056	0.9388	1
Loa Loa (eye worm)	hypothetical protein	0.0056	0.9388	1
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0056	0.9388	1
Brugia malayi	Serotonin receptor	0.0056	0.9388	1
Schistosoma mansoni	amine GPCR	0.0056	0.9388	0.9381
Loa Loa (eye worm)	hypothetical protein	0.0056	0.9388	1
Brugia malayi	GnHR receptor homolog	0.0056	0.9388	1
Loa Loa (eye worm)	hypothetical protein	0.0056	0.9388	1
Brugia malayi	G-protein-linked acetylcholine receptor protein 2, putative	0.0056	0.9388	1
Schistosoma mansoni	peptide (allatostatin/somatostatin)-like receptor	0.0056	0.9388	0.9381
Echinococcus multilocularis	orexin receptor type 2	0.0056	0.9388	1
Brugia malayi	hypothetical protein	0.0056	0.9388	1
Loa Loa (eye worm)	hypothetical protein	0.0056	0.9388	1
Loa Loa (eye worm)	unidentified vitellogenin-linked transcript protein 6	0.0056	0.9388	1
Echinococcus granulosus	rhodopsin orphan GPCR	0.0056	0.9388	1
Schistosoma mansoni	amine GPCR	0.0056	0.9388	0.9381
Loa Loa (eye worm)	hypothetical protein	0.0056	0.9388	1
Schistosoma mansoni	opsin-like receptor	0.0056	0.9388	0.9381
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0056	0.9388	0.9381
Schistosoma mansoni	cpg binding protein	0.0028	0.4393	0.4331
Echinococcus granulosus	cytoplasmic intermediate filament protein	0.0013	0.1658	0.117
Onchocerca volvulus		0.0056	0.9388	1
Onchocerca volvulus		0.0056	0.9388	1
Echinococcus multilocularis	thyrotropin releasing hormone receptor	0.0056	0.9388	1
Loa Loa (eye worm)	hypothetical protein	0.0056	0.9388	1
Trichomonas vaginalis	conserved hypothetical protein	0.0006	0.0525	1
Echinococcus multilocularis	g protein coupled receptor	0.0056	0.9388	1
Echinococcus multilocularis	g protein coupled receptor	0.0056	0.9388	1
Echinococcus multilocularis	G protein coupled receptor 139	0.0056	0.9388	1
Brugia malayi	Intermediate filament tail domain containing protein	0.0026	0.4088	0.3742
Echinococcus multilocularis	lamin	0.0026	0.4088	0.3946
Echinococcus multilocularis	g-protein coupled receptor	0.0056	0.9388	1
Loa Loa (eye worm)	hypothetical protein	0.0056	0.9388	1
Echinococcus multilocularis	7TM GPCR, rhodopsin	0.0056	0.9388	1
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0056	0.9388	1
Loa Loa (eye worm)	intermediate filament protein	0.0026	0.4088	0.3727
Loa Loa (eye worm)	hypothetical protein	0.0056	0.9388	1
Echinococcus multilocularis	neuropeptide s receptor	0.0056	0.9388	1
Loa Loa (eye worm)	hypothetical protein	0.0056	0.9388	1
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0056	0.9388	1
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0056	0.9388	1
Schistosoma mansoni	histamine h1 receptor	0.0056	0.9388	0.9381
Brugia malayi	follicle stimulating hormone receptor	0.0056	0.9388	1
Onchocerca volvulus	Neuropeptide F receptor homolog	0.0056	0.9388	1
Schistosoma mansoni	biogenic amine receptor	0.0056	0.9388	0.9381
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0056	0.9388	1
Loa Loa (eye worm)	hypothetical protein	0.0056	0.9388	1
Brugia malayi	Serotonin receptor	0.0056	0.9388	1
Onchocerca volvulus		0.0056	0.9388	1
Echinococcus granulosus	histone lysine N methyltransferase MLL3	0.0009	0.0939	0.0348
Schistosoma mansoni	neuropeptide receptor	0.0056	0.9388	0.9381
Brugia malayi	RE15519p	0.0056	0.9388	1
Brugia malayi	hypothetical protein	0.0056	0.9388	1
Brugia malayi	ORL1-like opioid receptor	0.0056	0.9388	1
Loa Loa (eye worm)	G-protein coupled receptor	0.0056	0.9388	1
Echinococcus granulosus	hypothetical protein	0.0056	0.9388	1
Echinococcus granulosus	lamin dm0	0.0026	0.4088	0.3946
Schistosoma mansoni	lamin	0.0026	0.4088	0.4023
Echinococcus granulosus	somatostatin receptor	0.0056	0.9388	1
Echinococcus granulosus	orexin receptor type 2	0.0056	0.9388	1
Onchocerca volvulus		0.0056	0.9388	1
Echinococcus multilocularis	G protein coupled 5 hydroxytryptamine receptor	0.0056	0.9388	1
Echinococcus granulosus	neuropeptides capa receptor	0.0056	0.9388	1
Echinococcus granulosus	G protein coupled 5 hydroxytryptamine receptor	0.0056	0.9388	1
Echinococcus granulosus	thyrotropin releasing hormone receptor	0.0056	0.9388	1
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0056	0.9388	0.9381
Loa Loa (eye worm)	cytoplasmic intermediate filament protein	0.0014	0.1908	0.1146
Brugia malayi	gonadotropin-releasing hormone receptor 2	0.0056	0.9388	1
Trichomonas vaginalis	chromodomain helicase DNA binding protein, putative	0.0006	0.0525	1
Brugia malayi	hypothetical protein	0.0056	0.9388	1
Trichomonas vaginalis	conserved hypothetical protein	0.0006	0.0525	1
Brugia malayi	Tachykinin-like peptides receptor 99D	0.0056	0.9388	1
Onchocerca volvulus		0.0056	0.9388	1
Loa Loa (eye worm)	hypothetical protein	0.0056	0.9388	1
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0056	0.9388	0.9381
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0056	0.9388	0.9381
Schistosoma mansoni	lamin	0.0026	0.4088	0.4023
Onchocerca volvulus		0.0056	0.9388	1
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0056	0.9388	1
Schistosoma mansoni	opsin-like receptor	0.0056	0.9388	0.9381
Schistosoma mansoni	alpha-1 adrenergic receptor	0.0056	0.9388	0.9381
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0056	0.9388	1
Echinococcus granulosus	sex peptide receptor	0.0056	0.9388	1
Echinococcus multilocularis	pyroglutamylated rfamide peptide receptor	0.0056	0.9388	1
Echinococcus granulosus	neuropeptide receptor	0.0056	0.9388	1
Echinococcus multilocularis	neuropeptide Y receptor	0.0056	0.9388	1
Loa Loa (eye worm)	hypothetical protein	0.0056	0.9388	1
Loa Loa (eye worm)	hypothetical protein	0.0056	0.9388	1
Brugia malayi	sulfakinin receptor protein	0.0056	0.9388	1
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0056	0.9388	1
Loa Loa (eye worm)	hypothetical protein	0.0012	0.1572	0.0749
Echinococcus multilocularis	sex peptide receptor	0.0056	0.9388	1
Onchocerca volvulus		0.0056	0.9388	1
Brugia malayi	neuropeptide F receptor	0.0056	0.9388	1
Loa Loa (eye worm)	hypothetical protein	0.0056	0.9388	1
Loa Loa (eye worm)	hypothetical protein	0.0056	0.9388	1
Echinococcus granulosus	g-protein coupled receptor	0.0056	0.9388	1
Trichomonas vaginalis	conserved hypothetical protein	0.0006	0.0525	1
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0056	0.9388	1
Schistosoma mansoni	amine GPCR	0.0056	0.9388	0.9381
Loa Loa (eye worm)	hypothetical protein	0.0056	0.9388	1
Echinococcus granulosus	g protein coupled receptor	0.0056	0.9388	1
Loa Loa (eye worm)	hypothetical protein	0.0056	0.9388	1
Brugia malayi	G-protein coupled receptor	0.0056	0.9388	1
Brugia malayi	hypothetical protein	0.0056	0.9388	1
Schistosoma mansoni	ancient conserved domain protein 2 (cyclin m2)	0.0056	0.9388	0.9381
Echinococcus granulosus	rhodopsin orphan GPCR	0.0056	0.9388	1
Trichomonas vaginalis	helicase, putative	0.0006	0.0525	1
Schistosoma mansoni	biogenic amine receptor	0.0056	0.9388	0.9381
Toxoplasma gondii	histone lysine methyltransferase SET1	0.0053	0.8867	0.5
Loa Loa (eye worm)	hypothetical protein	0.0026	0.4088	0.3727
Echinococcus granulosus	serotonin receptor	0.0056	0.9388	1
Echinococcus granulosus	pyroglutamylated rfamide peptide receptor	0.0056	0.9388	1
Loa Loa (eye worm)	G-protein coupled receptor	0.0056	0.9388	1
Trichomonas vaginalis	conserved hypothetical protein	0.0006	0.0525	1
Trichomonas vaginalis	chromodomain helicase DNA binding protein, putative	0.0006	0.0525	1
Echinococcus granulosus	rhodopsin orphan GPCR	0.0056	0.9388	1
Echinococcus multilocularis	neuropeptide receptor	0.0056	0.9388	1
Brugia malayi	Dopamine receptor protein 1	0.0056	0.9388	1
Loa Loa (eye worm)	hypothetical protein	0.0056	0.9388	1
Schistosoma mansoni	neuropeptide receptor	0.0056	0.9388	0.9381
Loa Loa (eye worm)	follicle stimulating hormone receptor	0.0056	0.9388	1
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0056	0.9388	1
Trichomonas vaginalis	conserved hypothetical protein	0.0006	0.0525	1
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0056	0.9388	1
Trichomonas vaginalis	conserved hypothetical protein	0.0006	0.0525	1
Echinococcus multilocularis	neuropeptides capa receptor	0.0056	0.9388	1
Echinococcus granulosus	biogenic amine 5HT receptor	0.0056	0.9388	1
Schistosoma mansoni	mixed-lineage leukemia protein mll	0.0007	0.0634	0.0531
Echinococcus multilocularis	neuropeptide receptor A26	0.0056	0.9388	1
Onchocerca volvulus		0.0056	0.9388	1
Brugia malayi	G-protein coupled receptor	0.0056	0.9388	1
Loa Loa (eye worm)	hypothetical protein	0.0056	0.9388	1
Schistosoma mansoni	myosin xvIII	0.0056	0.9388	0.9381
Schistosoma mansoni	adenoreceptor	0.0056	0.9388	0.9381
Echinococcus multilocularis	g protein coupled receptor	0.0056	0.9388	1
Brugia malayi	Melatonin receptor type 1A	0.0056	0.9388	1
Echinococcus multilocularis	fmrfamide receptor	0.0056	0.9388	1
Schistosoma mansoni	growth hormone secretagogue receptor	0.0056	0.9388	0.9381
Echinococcus granulosus	fmrfamide receptor	0.0056	0.9388	1
Echinococcus granulosus	intermediate filament protein	0.0026	0.4088	0.3946
Echinococcus granulosus	tm gpcr rhodopsin	0.0056	0.9388	1
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0056	0.9388	0.9381
Brugia malayi	neuropeptide F receptor	0.0056	0.9388	1
Echinococcus granulosus	G protein coupled receptor 139	0.0056	0.9388	1
Echinococcus granulosus	tachykinin peptides receptor 99D	0.0056	0.9388	1
Loa Loa (eye worm)	hypothetical protein	0.0056	0.9388	1
Echinococcus multilocularis	G-protein coupled receptor, putative	0.0056	0.9388	1
Trichomonas vaginalis	chromodomain-helicase-DNA-binding protein, putative	0.0006	0.0525	1
Echinococcus multilocularis	allatostatin A receptor	0.0056	0.9388	1
Echinococcus granulosus	growth hormone secretagogue receptor type 1	0.0056	0.9388	1
Echinococcus granulosus	tm gpcr rhodopsin	0.0056	0.9388	1
Echinococcus multilocularis	neuropeptide receptor	0.0056	0.9388	1
Onchocerca volvulus		0.0056	0.9388	1
Echinococcus granulosus	rhodopsin orphan GPCR	0.0056	0.9388	1
Echinococcus granulosus	neuropeptide Y receptor	0.0056	0.9388	1
Loa Loa (eye worm)	hypothetical protein	0.0056	0.9388	1
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0056	0.9388	0.9381
Trichomonas vaginalis	chromodomain helicase DNA binding protein, putative	0.0006	0.0525	1
Echinococcus granulosus	neuropeptide FF receptor 2	0.0056	0.9388	1
Echinococcus multilocularis	alpha 1A adrenergic receptor	0.0056	0.9388	1
Brugia malayi	AKH receptor	0.0056	0.9388	1
Loa Loa (eye worm)	hypothetical protein	0.0056	0.9388	1
Loa Loa (eye worm)	hypothetical protein	0.0056	0.9388	1
Brugia malayi	hypothetical protein	0.0056	0.9388	1
Brugia malayi	hypothetical protein	0.0056	0.9388	1
Schistosoma mansoni	thyrotropin-releasing hormone receptor	0.0056	0.9388	0.9381
Echinococcus multilocularis	musashi	0.0026	0.4088	0.3946
Onchocerca volvulus		0.0028	0.4393	0.0576
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0056	0.9388	0.9381
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0056	0.9388	0.9381
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0056	0.9388	1
Loa Loa (eye worm)	hypothetical protein	0.0056	0.9388	1
Loa Loa (eye worm)	CXXC zinc finger family protein	0.0028	0.4393	0.4088
Trichomonas vaginalis	chromodomain helicase DNA binding protein, putative	0.0006	0.0525	1
Echinococcus granulosus	g protein coupled receptor	0.0056	0.9388	1
Loa Loa (eye worm)	hypothetical protein	0.0056	0.9388	1
Loa Loa (eye worm)	hypothetical protein	0.0056	0.9388	1
Echinococcus granulosus	neuropeptide Y receptor	0.0056	0.9388	1
Brugia malayi	hypothetical protein	0.0056	0.9388	1
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0056	0.9388	0.9381
Loa Loa (eye worm)	hypothetical protein	0.0056	0.9388	1
Brugia malayi	Dopamine receptor protein 2	0.0056	0.9388	1
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0056	0.9388	0.9381
Trichomonas vaginalis	chromodomain-helicase-DNA-binding protein, putative	0.0006	0.0525	1
Echinococcus granulosus	neuropeptide receptor	0.0056	0.9388	1
Onchocerca volvulus		0.0056	0.9388	1
Echinococcus multilocularis	somatostatin receptor	0.0056	0.9388	1
Loa Loa (eye worm)	hypothetical protein	0.0056	0.9388	1
Loa Loa (eye worm)	hypothetical protein	0.0026	0.4002	0.3625
Loa Loa (eye worm)	hypothetical protein	0.0056	0.9388	1
Schistosoma mansoni	hypothetical protein	0.0056	0.9388	0.9381
Schistosoma mansoni	intermediate filament proteins	0.0026	0.4088	0.4023
Echinococcus granulosus	rhodopsin orphan GPCR	0.0056	0.9388	1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL3221620

Bibliographic References

No literature references available for this target.

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Detailed information for compound 1850045