Detailed information for compound 1853785

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 355.431 | Formula: C20H25N3O3
  • H donors: 1 H acceptors: 3 LogP: 2.88 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: N#C[C@@H]1CCCN1C(=O)C1(CCCCC1)NC(=O)OCc1ccccc1
  • InChi: 1S/C20H25N3O3/c21-14-17-10-7-13-23(17)18(24)20(11-5-2-6-12-20)22-19(25)26-15-16-8-3-1-4-9-16/h1,3-4,8-9,17H,2,5-7,10-13,15H2,(H,22,25)/t17-/m0/s1
  • InChiKey: NVPBGSSWCATGCC-KRWDZBQOSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) MH1 domain-containing protein 0.0008 0.0019 0.0066
Echinococcus multilocularis fibroblast growth factor receptor 4 0.055 0.2549 0.9998
Loa Loa (eye worm) hypothetical protein 0.0036 0.0149 0.0578
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.0151 1
Brugia malayi Protein kinase domain containing protein 0.055 0.2549 1
Brugia malayi Protein kinase domain containing protein 0.055 0.2549 1
Entamoeba histolytica ankyrin repeat protein 0.055 0.2549 0.9998
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.055 0.2549 0.9998
Schistosoma mansoni protein kinase 0.055 0.2549 0.9998
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0029 0.0117 0.1175
Brugia malayi Protein kinase domain containing protein 0.055 0.2549 1
Entamoeba histolytica protein kinase domain containing protein 0.055 0.2549 0.9998
Echinococcus granulosus tyrosine kinase 0.055 0.2549 0.9998
Onchocerca volvulus 0.0005 0.0003 0.0000042611
Schistosoma mansoni ankyrin 23/unc44 0.0028 0.0114 0.0447
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0063 0.0275 0.1071
Entamoeba histolytica hypothetical protein 0.055 0.2549 0.9998
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0151 0.0335
Entamoeba histolytica SH2-protein kinase domain containing protein 0.055 0.2549 0.9998
Brugia malayi Raf kinase 0.055 0.2549 1
Loa Loa (eye worm) TK/ROR protein kinase 0.055 0.2549 1
Schistosoma mansoni protein kinase 0.055 0.2549 0.9998
Loa Loa (eye worm) hypothetical protein 0.0005 0.0003 0.0005
Echinococcus granulosus insulin growth factor 1 receptor beta 0.055 0.2549 0.9998
Echinococcus multilocularis retinal guanylyl cyclase 2 0.055 0.2549 0.9998
Echinococcus granulosus retinoic acid receptor rxr beta a 0.001 0.0028 0.0097
Loa Loa (eye worm) Smad1 0.0008 0.0019 0.0066
Schistosoma mansoni tyrosine kinase 0.055 0.2549 0.9998
Schistosoma mansoni tyrosine kinase 0.055 0.2549 0.9998
Entamoeba histolytica protein kinase domain containing protein 0.055 0.2549 0.9998
Echinococcus multilocularis tyrosine protein kinase Fyn 0.055 0.2549 0.9998
Entamoeba histolytica hypothetical protein, conserved 0.055 0.2549 0.9998
Entamoeba histolytica tyrosine kinase, putative 0.055 0.2549 0.9998
Toxoplasma gondii 6-phosphofructokinase 0.0029 0.0117 0.0197
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.0485 0.1679
Toxoplasma gondii protein kinase domain-containing protein 0.055 0.2549 1
Trypanosoma brucei Flagellum attachment zone protein 20 0.055 0.2549 1
Entamoeba histolytica protein kinase domain containing protein 0.055 0.2549 0.9998
Entamoeba histolytica hypothetical protein 0.0136 0.0618 0.2215
Schistosoma mansoni ephrin receptor 0.055 0.2549 0.9998
Brugia malayi 6-phosphofructokinase 0.0108 0.0485 0.1896
Echinococcus multilocularis GPCR, family 2 0.0036 0.0149 0.0574
Echinococcus granulosus dual specificity testis-specific protein kinase 0.055 0.2549 0.9998
Loa Loa (eye worm) hypothetical protein 0.0005 0.0006 0.0015
Entamoeba histolytica protein kinase domain containing protein 0.055 0.2549 0.9998
Schistosoma mansoni tyrosine kinase 0.055 0.2549 0.9998
Echinococcus granulosus netrin receptor unc 5 0.0028 0.0114 0.0435
Brugia malayi nuclear hormone receptor family member nhr-6 0.0005 0.0003 0.0005
Trichomonas vaginalis TKL family protein kinase 0.055 0.2549 0.254
Echinococcus granulosus protein tyrosine kinase 0.055 0.2549 0.9998
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0036 0.0149 0.0574
Trichomonas vaginalis TKL family protein kinase 0.055 0.2549 0.254
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0117 0.5
Loa Loa (eye worm) TK/FER protein kinase 0.055 0.2549 1
Giardia lamblia NADPH oxidoreductase, putative 0.0136 0.0618 0.2215
Echinococcus multilocularis netrin receptor unc 5 0.0028 0.0114 0.0435
Trichomonas vaginalis TKL family protein kinase 0.055 0.2549 0.254
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0117 0.0106
Loa Loa (eye worm) hypothetical protein 0.0005 0.0003 0.0005
Loa Loa (eye worm) hypothetical protein 0.0005 0.0003 0.0005
Loa Loa (eye worm) TK/FER protein kinase 0.055 0.2549 1
Trichomonas vaginalis modulator of drug activity B, putative 0.0136 0.0618 0.0607
Entamoeba histolytica protein kinase, putative 0.055 0.2549 0.9998
Echinococcus granulosus ephrin type A receptor 4 A 0.055 0.2549 0.9998
Echinococcus granulosus activin receptor type 0.055 0.2549 0.9998
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0151 0.0582
Loa Loa (eye worm) hypothetical protein 0.0005 0.0006 0.0015
Loa Loa (eye worm) TK/KIN6 protein kinase 0.055 0.2549 1
Loa Loa (eye worm) TK protein kinase 0.055 0.2549 1
Schistosoma mansoni tyrosine kinase 0.055 0.2549 0.9998
Trichomonas vaginalis TK family protein kinase 0.055 0.2549 0.254
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.055 0.2549 0.9998
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0005 0.0006 0.0023
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.0133 0.1569
Onchocerca volvulus 0.055 0.2549 1
Brugia malayi CXXC zinc finger family protein 0.0028 0.0113 0.0438
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0029 0.0117 0.0197
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.055 0.2549 1
Brugia malayi Receptor family ligand binding region containing protein 0.055 0.2549 1
Loa Loa (eye worm) hypothetical protein 0.0005 0.0003 0.0005
Loa Loa (eye worm) TK/FER protein kinase 0.055 0.2549 1
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.055 0.2549 0.9998
Schistosoma mansoni protein kinase 0.055 0.2549 1
Trichomonas vaginalis conserved hypothetical protein 0.055 0.2549 0.254
Trichomonas vaginalis conserved hypothetical protein 0.0136 0.0618 0.0607
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.055 0.2549 1
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.055 0.2549 0.9998
Brugia malayi hypothetical protein 0.0005 0.0003 0.0005
Brugia malayi Protein kinase domain containing protein 0.055 0.2549 1
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.055 0.2549 0.9998
Brugia malayi Nuclear hormone receptor E75 0.0005 0.0003 0.0005
Entamoeba histolytica hypothetical protein 0.055 0.2549 0.9998
Entamoeba histolytica tyrosine kinase, putative 0.055 0.2549 0.9998
Brugia malayi tailless protein 0.0005 0.0003 0.0005
Schistosoma mansoni tyrosine kinase 0.055 0.2549 0.9998
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.0005 0.0003 0.0005
Trichomonas vaginalis modulator of drug activity B, putative 0.0136 0.0618 0.0607
Echinococcus granulosus raf serine:threonine protein kinase 0.055 0.2549 0.9998
Brugia malayi Immunoglobulin I-set domain containing protein 0.055 0.2549 1
Onchocerca volvulus 0.055 0.2549 1
Schistosoma mansoni serine/threonine protein kinase 0.055 0.2549 0.9998
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.001 0.0028 0.0102
Entamoeba histolytica protein kinase, putative 0.055 0.2549 0.9998
Echinococcus multilocularis Low density lipoprotein receptor, class A, cysteine rich 0.0005 0.0003 0.0000042602
Brugia malayi hypothetical protein 0.0005 0.0003 0.0005
Brugia malayi phosphofructokinase 0.0108 0.0485 0.1896
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0151 0.0582
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0275 0.1077
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.001 0.0028 0.0102
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0028 0.0097
Trichomonas vaginalis conserved hypothetical protein 0.0136 0.0618 0.0607
Echinococcus multilocularis tyrosine protein kinase pr2 0.055 0.2549 0.9998
Loa Loa (eye worm) TK/FER protein kinase 0.055 0.2549 1
Brugia malayi Death domain containing protein 0.0028 0.0114 0.044
Onchocerca volvulus 0.0005 0.0003 0.0000042611
Brugia malayi Nuclear hormone receptor family member nhr-3 0.001 0.0028 0.0102
Trichomonas vaginalis CAMK family protein kinase 0.055 0.2549 0.254
Echinococcus granulosus tyrosine protein kinase Fyn 0.055 0.2549 0.9998
Trichomonas vaginalis conserved hypothetical protein 0.0136 0.0618 0.0607
Echinococcus granulosus tyrosine protein kinase Src42A 0.055 0.2549 0.9998
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0117 0.0197
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0028 0.0114 0.044
Echinococcus granulosus nuclear factor of activated T cells 5 0.0278 0.128 0.5015
Entamoeba histolytica protein kinase domain containing protein 0.055 0.2549 0.9998
Echinococcus multilocularis ephrin type A receptor 4 A 0.055 0.2549 0.9998
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0036 0.0149 0.0578
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0108 0.0485 1
Schistosoma mansoni tyrosine kinase 0.055 0.2549 0.9998
Schistosoma mansoni protein kinase 0.055 0.2549 0.9998
Trichomonas vaginalis modulator of drug activity B, putative 0.0136 0.0618 0.0607
Brugia malayi Protein kinase domain containing protein 0.055 0.2549 1
Brugia malayi Protein kinase domain containing protein 0.055 0.2549 1
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.055 0.2549 0.9998
Onchocerca volvulus Protein ultraspiracle homolog 0.001 0.0028 0.0097
Schistosoma mansoni retinoic acid receptor RXR 0.001 0.0028 0.0109
Echinococcus multilocularis tyrosine protein kinase csk 0.055 0.2549 0.9998
Trichomonas vaginalis modulator of drug activity B, putative 0.0136 0.0618 0.0607
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0108 0.0485 1
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0151 0.0335
Giardia lamblia Kinase, NEK 0.055 0.2549 0.9998
Schistosoma mansoni tyrosine kinase 0.055 0.2549 0.9998
Echinococcus granulosus activated cdc42 kinase 1 0.055 0.2549 0.9998
Entamoeba histolytica protein kinase, putative 0.055 0.2549 0.9998
Schistosoma mansoni smad1 5 8 and 0.0008 0.0019 0.0073
Schistosoma mansoni protein kinase 0.055 0.2549 0.9998
Schistosoma mansoni smad1 5 8 and 0.0008 0.0019 0.0073
Trypanosoma cruzi protein kinase, putative 0.055 0.2549 1
Brugia malayi nuclear hormone receptor 0.001 0.0028 0.0102
Brugia malayi Low-density lipoprotein receptor domain class A containing protein 0.0005 0.0003 0.0005
Trichomonas vaginalis TKL family protein kinase 0.055 0.2549 0.254
Schistosoma mansoni tyrosine kinase 0.055 0.2549 0.9998
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.055 0.2549 0.9998
Brugia malayi ephrin receptor 1 precursor 0.055 0.2549 1
Echinococcus multilocularis cpg binding protein 0.003 0.0121 0.0463
Echinococcus granulosus natriuretic peptide receptor 1 0.055 0.2549 0.9998
Loa Loa (eye worm) hypothetical protein 0.0005 0.0003 0.0005
Plasmodium falciparum tyrosine kinase-like protein 0.055 0.2549 1
Brugia malayi Inositol-1 0.0036 0.0151 0.0587
Loa Loa (eye worm) hypothetical protein 0.001 0.0028 0.0102
Trichomonas vaginalis TKL family protein kinase 0.055 0.2549 0.254
Trichomonas vaginalis TKL family protein kinase 0.055 0.2549 0.254
Loa Loa (eye worm) hypothetical protein 0.0005 0.0003 0.0005
Echinococcus multilocularis retinal guanylyl cyclase 2 0.055 0.2549 0.9998
Schistosoma mansoni smad1 5 8 and 0.0008 0.0019 0.0073
Schistosoma mansoni tyrosine kinase 0.055 0.2549 0.9998
Onchocerca volvulus Netrin receptor homolog 0.0028 0.0114 0.0435
Trichomonas vaginalis TKL family protein kinase 0.055 0.2549 0.254
Entamoeba histolytica cysteine surface protein, putative 0.055 0.2549 0.9998
Plasmodium falciparum protein kinase, putative 0.055 0.2549 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0028 0.0097
Schistosoma mansoni tyrosine kinase 0.055 0.2549 0.9998
Trichomonas vaginalis TKL family protein kinase 0.055 0.2549 0.254
Schistosoma mansoni mixed-lineage leukemia protein mll 0.006 0.0262 0.1027
Echinococcus granulosus epidermal growth factor receptor 0.055 0.2549 0.9998
Trichomonas vaginalis modulator of drug activity B, putative 0.0136 0.0618 0.0607
Echinococcus granulosus c src tyrosine kinase 0.055 0.2549 0.9998
Brugia malayi nuclear hormone receptor family member odr-7 0.0005 0.0003 0.0005
Entamoeba histolytica protein kinase, putative 0.055 0.2549 0.9998
Trichomonas vaginalis TKL family protein kinase 0.055 0.2549 0.254
Onchocerca volvulus 0.001 0.0028 0.0097
Loa Loa (eye worm) TK protein kinase 0.055 0.2549 1
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.055 0.2549 1
Entamoeba histolytica hypothetical protein 0.055 0.2549 1
Echinococcus granulosus tyrosine protein kinase Lyn 0.055 0.2549 0.9998
Entamoeba histolytica tyrosine kinase, putative 0.055 0.2549 0.9998
Entamoeba histolytica receptor protein kinase, putative 0.055 0.2549 0.9998
Loa Loa (eye worm) hypothetical protein 0.055 0.2549 1
Trichomonas vaginalis TKL family protein kinase 0.055 0.2549 0.254
Trichomonas vaginalis TKL family protein kinase 0.055 0.2549 0.254
Loa Loa (eye worm) hypothetical protein 0.055 0.2549 1
Plasmodium vivax protein kinase, putative 0.055 0.2549 1
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0005 0.0003 0.0000042602
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.055 0.2549 1
Schistosoma mansoni cpg binding protein 0.003 0.0121 0.0475
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0005 0.0003 0.0012
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.055 0.2549 0.9998
Schistosoma mansoni tyrosine kinase 0.055 0.2549 0.9998
Entamoeba histolytica hypothetical protein 0.055 0.2549 0.9998
Trichomonas vaginalis TKL family protein kinase 0.055 0.2549 0.254
Loa Loa (eye worm) hypothetical protein 0.0029 0.0114 0.0442
Schistosoma mansoni zinc finger protein 0.0005 0.0003 0.0012
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.055 0.2549 0.9998
Entamoeba histolytica tyrosin kinase, putative 0.055 0.2549 0.9998
Entamoeba histolytica protein kinase domain containing protein 0.055 0.2549 0.9998
Trichomonas vaginalis serine-threonine protein kinase, putative 0.055 0.2549 0.254
Loa Loa (eye worm) hypothetical protein 0.0005 0.0003 0.0005
Brugia malayi Protein kinase domain containing protein 0.055 0.2549 1
Trichomonas vaginalis modulator of drug activity B, putative 0.0136 0.0618 0.0607
Trichomonas vaginalis AGC family protein kinase 0.055 0.2549 0.254
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.055 0.2549 0.9998
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.001 0.0028 0.0097
Loa Loa (eye worm) hypothetical protein 0.0005 0.0006 0.0015
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.055 0.2549 0.9998
Loa Loa (eye worm) protein kinase domain-containing protein 0.055 0.2549 1
Brugia malayi Nuclear hormone receptor family member nhr-49 0.001 0.0028 0.0102
Schistosoma mansoni hypothetical protein 0.055 0.2549 0.9998
Brugia malayi Uncoordinated protein 44 0.0028 0.0114 0.044
Brugia malayi Protein kinase domain containing protein 0.055 0.2549 1
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.001 0.0028 0.0097
Echinococcus multilocularis epidermal growth factor receptor 0.055 0.2549 0.9998
Loa Loa (eye worm) hypothetical protein 0.0005 0.0003 0.0005
Loa Loa (eye worm) calcium binding EGF domain-containing protein 0.0005 0.0003 0.0005
Echinococcus multilocularis 6 phosphofructokinase 0.0108 0.0485 0.1891
Giardia lamblia NADPH oxidoreductase, putative 0.0136 0.0618 0.2215
Entamoeba histolytica protein kinase, putative 0.055 0.2549 0.9998
Echinococcus multilocularis raf serine:threonine protein kinase 0.055 0.2549 0.9998
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0068 0.0057
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.055 0.2549 0.9998
Entamoeba histolytica protein kinase domain containing protein 0.055 0.2549 0.9998
Onchocerca volvulus 0.0005 0.0003 0.0000042611
Onchocerca volvulus 0.0005 0.0003 0.0000042611
Brugia malayi photoreceptor-specific nuclear receptor 0.001 0.0028 0.0102
Loa Loa (eye worm) RGC/RGC protein kinase 0.055 0.2549 1
Loa Loa (eye worm) hypothetical protein 0.001 0.0028 0.0102
Entamoeba histolytica protein kinase domain containing protein 0.055 0.2549 0.9998
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.055 0.2549 0.9998
Schistosoma mansoni serine/threonine protein kinase 0.055 0.2549 0.9998
Loa Loa (eye worm) hypothetical protein 0.055 0.2549 1
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0114 0.0512 0.2005
Brugia malayi nuclear receptor RXR 0.0005 0.0003 0.0005
Schistosoma mansoni tyrosine-protein kinase fps85d 0.055 0.2549 0.9998
Schistosoma mansoni serine/threonine protein kinase 0.055 0.2549 0.9998
Echinococcus multilocularis tyrosine protein kinase Fyn 0.055 0.2549 0.9998
Brugia malayi nuclear hormone receptor 0.0005 0.0003 0.0005
Loa Loa (eye worm) TK/ACK protein kinase 0.055 0.2549 1
Trichomonas vaginalis modulator of drug activity B, putative 0.0136 0.0618 0.0607
Schistosoma mansoni nuclear hormone receptor 0.0005 0.0003 0.0012
Loa Loa (eye worm) hypothetical protein 0.0005 0.0003 0.0005
Echinococcus multilocularis ecdysone induced protein 78C 0.001 0.0028 0.0097
Schistosoma mansoni tyrosine kinase 0.055 0.2549 0.9998
Trichomonas vaginalis modulator of drug activity B, putative 0.0136 0.0618 0.0607
Brugia malayi Nuclear hormone receptor-like 1 0.0005 0.0006 0.0015
Entamoeba histolytica tyrosine kinase, putative 0.055 0.2549 0.9998
Loa Loa (eye worm) RGC/RGC protein kinase 0.055 0.2549 1
Brugia malayi steroid hormone receptor 0.001 0.0028 0.0102
Brugia malayi 6-phosphofructokinase 0.0108 0.0485 0.1896
Entamoeba histolytica hypothetical protein 0.055 0.2549 0.9998
Brugia malayi C-terminal src kinase protein 1 0.055 0.2549 1
Echinococcus granulosus fibroblast growth factor receptor 4 0.055 0.2549 0.9998
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.001 0.0028 0.0109
Plasmodium falciparum protein kinase, putative 0.055 0.2549 1
Plasmodium vivax tyrosine kinase-like protein, putative 0.055 0.2549 1
Echinococcus multilocularis Low density lipoprotein receptor, class A, cysteine rich 0.0005 0.0003 0.0000042602
Brugia malayi hypothetical protein 0.0005 0.0006 0.0015
Trichomonas vaginalis TKL family protein kinase 0.055 0.2549 0.254
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0005 0.0006 0.0015
Schistosoma mansoni protein kinase 0.055 0.2549 0.9998
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0151 0.0335
Loa Loa (eye worm) hypothetical protein 0.0005 0.0003 0.0005
Brugia malayi Low-density lipoprotein receptor domain class A containing protein 0.0005 0.0003 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.055 0.2549 0.254
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0007 0.0014 0.0042
Echinococcus multilocularis FL cytokine receptor 0.055 0.2549 0.9998
Brugia malayi MH1 domain containing protein 0.0008 0.0019 0.0066
Entamoeba histolytica tyrosine kinase, putative 0.055 0.2549 0.9998
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.0005 0.0003 0.0005
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0275 0.1077
Loa Loa (eye worm) TK/FAK protein kinase 0.055 0.2549 1
Entamoeba histolytica tyrosin kinase, putative 0.055 0.2549 0.9998
Brugia malayi Steroid receptor seven-up type 2 0.001 0.0028 0.0102
Loa Loa (eye worm) hypothetical protein 0.055 0.2549 1
Trichomonas vaginalis TKL family protein kinase 0.055 0.2549 0.254
Entamoeba histolytica serine/threonine kinase, putative 0.055 0.2549 0.9998
Echinococcus granulosus 5'partial|Low density lipoprotein receptor class A cysteine rich 0.0005 0.0003 0.0000042602
Onchocerca volvulus 0.055 0.2549 1
Loa Loa (eye worm) hypothetical protein 0.0005 0.0003 0.0005
Onchocerca volvulus 0.055 0.2549 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.001 0.0028 0.0102
Brugia malayi Furin-like cysteine rich region family protein 0.055 0.2549 1
Trichomonas vaginalis TKL family protein kinase 0.055 0.2549 0.254
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.055 0.2549 0.9998
Entamoeba histolytica protein kinase domain containing protein 0.055 0.2549 0.9998
Loa Loa (eye worm) low-density lipoprotein receptor domain class A containing protein 0.0005 0.0003 0.0005
Loa Loa (eye worm) hypothetical protein 0.001 0.0028 0.0102
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.055 0.2549 1
Entamoeba histolytica protein kinase domain containing protein 0.055 0.2549 0.9998
Entamoeba histolytica protein kinase, putative 0.055 0.2549 0.9998
Entamoeba histolytica tyrosin kinase, putative 0.055 0.2549 0.9998
Brugia malayi Protein kinase domain containing protein 0.055 0.2549 1
Loa Loa (eye worm) TK/CSK protein kinase 0.055 0.2549 1
Entamoeba histolytica protein kinase domain containing protein 0.055 0.2549 0.9998
Loa Loa (eye worm) RNA binding protein 0.0063 0.0275 0.1071
Brugia malayi Protein kinase domain containing protein 0.055 0.2549 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0028 0.0097
Trichomonas vaginalis TKL family protein kinase 0.055 0.2549 0.254
Echinococcus granulosus retinal guanylyl cyclase 2 0.055 0.2549 0.9998
Loa Loa (eye worm) TK protein kinase 0.055 0.2549 1
Loa Loa (eye worm) TK protein kinase 0.055 0.2549 1
Entamoeba histolytica protein kinase, putative 0.055 0.2549 0.9998
Echinococcus multilocularis integrin linked protein kinase 0.055 0.2549 0.9998
Echinococcus granulosus TGF beta signal transducer SmadC 0.0008 0.0019 0.0061
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0028 0.0102
Loa Loa (eye worm) SRC-1 0.055 0.2549 1
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.055 0.2549 1
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.055 0.2549 1
Brugia malayi Protein kinase domain containing protein 0.055 0.2549 1
Entamoeba histolytica protein kinase, putative 0.055 0.2549 0.9998
Onchocerca volvulus 0.055 0.2549 1
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.055 0.2549 1
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0151 0.0335
Echinococcus granulosus tyrosine protein kinase Src64B 0.055 0.2549 0.9998
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0036 0.0149 0.0574
Entamoeba histolytica protein kinase domain containing protein 0.055 0.2549 0.9998
Trichomonas vaginalis conserved hypothetical protein 0.055 0.2549 0.254
Echinococcus granulosus ecdysone induced protein 78C 0.001 0.0028 0.0097
Trichomonas vaginalis conserved hypothetical protein 0.0136 0.0618 0.0607
Echinococcus multilocularis Low density lipoprotein receptor, class A, cysteine rich 0.0005 0.0003 0.0000042602
Entamoeba histolytica protein kinase, putative 0.055 0.2549 0.9998
Loa Loa (eye worm) transcription factor SMAD2 0.0118 0.0534 0.209
Trichomonas vaginalis conserved hypothetical protein 0.0136 0.0618 0.0607
Loa Loa (eye worm) TK/FER protein kinase 0.055 0.2549 1
Echinococcus granulosus tyrosine protein kinase Fyn 0.055 0.2549 0.9998
Brugia malayi bone morphogenetic protein type 1 receptor 0.055 0.2549 1
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0151 0.1997
Schistosoma mansoni tyrosine kinase 0.055 0.2549 0.9998
Entamoeba histolytica tyrosine kinase, putative 0.055 0.2549 0.9998
Entamoeba histolytica tyrosine kinase, putative 0.055 0.2549 0.9998
Brugia malayi Smad1 0.0008 0.0019 0.0066
Trichomonas vaginalis TKL family protein kinase 0.055 0.2549 0.254
Echinococcus multilocularis protein tyrosine kinase 0.055 0.2549 0.9998
Trichomonas vaginalis conserved hypothetical protein 0.0136 0.0618 0.0607
Brugia malayi Nuclear hormone receptor family member nhr-14 0.001 0.0028 0.0102
Echinococcus granulosus low density lipoprotein receptor ldl 0.0005 0.0003 0.0000042602
Schistosoma mansoni tyrosine kinase 0.055 0.2549 0.9998
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.055 0.2549 0.9998
Brugia malayi orphan nuclear receptor NR2E1 0.0005 0.0003 0.0005
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.001 0.0028 0.0097
Loa Loa (eye worm) hypothetical protein 0.0005 0.0003 0.0005
Onchocerca volvulus Tyrosine kinase homolog 0.055 0.2549 1
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.001 0.0028 0.0097
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.055 0.2549 0.254
Entamoeba histolytica protein kinase, putative 0.055 0.2549 0.9998
Echinococcus multilocularis tyrosine protein kinase Fgr 0.055 0.2549 0.9998
Leishmania major hypothetical protein, conserved 0.055 0.2549 1
Schistosoma mansoni hypothetical protein 0.0036 0.0149 0.0585
Echinococcus multilocularis tyrosine protein kinase Srms 0.055 0.2549 0.9998
Trichomonas vaginalis conserved hypothetical protein 0.0136 0.0618 0.0607
Brugia malayi Tyrosine-protein kinase PR2 0.055 0.2549 1
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0005 0.0003 0.0005
Loa Loa (eye worm) hypothetical protein 0.0005 0.0003 0.0005
Loa Loa (eye worm) hypothetical protein 0.0005 0.0003 0.0005
Echinococcus multilocularis Smad4 0.0008 0.0019 0.0061
Echinococcus granulosus dnaJ subfamily B 0.0404 0.1867 0.7322
Echinococcus granulosus Smad4 0.0008 0.0019 0.0061
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.055 0.2549 0.9998
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0117 0.0106
Echinococcus granulosus Ankyrin 0.0029 0.0114 0.0437
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.055 0.2549 0.9998
Trichomonas vaginalis modulator of drug activity B, putative 0.0136 0.0618 0.0607
Loa Loa (eye worm) RGC/RGC protein kinase 0.055 0.2549 1
Trichomonas vaginalis conserved hypothetical protein 0.0136 0.0618 0.0607
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0028 0.0114 0.0435
Trichomonas vaginalis conserved hypothetical protein 0.0136 0.0618 0.0607
Echinococcus granulosus tyrosine protein kinase ABL1 0.055 0.2549 0.9998
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.001 0.0028 0.0102
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.001 0.0028 0.0097
Echinococcus multilocularis FTZ F1 alpha 0.001 0.0028 0.0097
Schistosoma mansoni Smad4 0.0008 0.0019 0.0073
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.055 0.2549 1
Trichomonas vaginalis conserved hypothetical protein 0.0136 0.0618 0.0607
Onchocerca volvulus 0.055 0.2549 1
Trichomonas vaginalis TKL family protein kinase 0.055 0.2549 0.254
Brugia malayi Low-density lipoprotein receptor domain class A containing protein 0.0005 0.0003 0.0005
Echinococcus granulosus tyrosine protein kinase Fyn 0.055 0.2549 0.9998
Schistosoma mansoni tyrosine kinase 0.055 0.2549 0.9998
Loa Loa (eye worm) hypothetical protein 0.055 0.2549 1
Brugia malayi CUB domain containing protein 0.0005 0.0003 0.0005
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0005 0.0003 0.0012
Trichomonas vaginalis TKL family protein kinase 0.055 0.2549 0.254
Schistosoma mansoni hypothetical protein 0.0085 0.0377 0.1479
Loa Loa (eye worm) RGC/RGC protein kinase 0.055 0.2549 1
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0029 0.0114 0.0449
Echinococcus granulosus low density lipoprotein receptor ldl 0.0005 0.0003 0.0000042602
Echinococcus multilocularis tyrosine protein kinase shark 0.055 0.2549 1
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.055 0.2549 0.9998
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0485 0.0474
Brugia malayi Protein kinase domain containing protein 0.055 0.2549 1
Echinococcus granulosus tyrosine kinase 0.055 0.2549 0.9998
Entamoeba histolytica protein kinase domain containing protein 0.055 0.2549 0.9998
Loa Loa (eye worm) hypothetical protein 0.0005 0.0003 0.0005
Brugia malayi Protein kinase domain containing protein 0.055 0.2549 1
Echinococcus multilocularis tyrosine protein kinase 0.055 0.2549 0.9998
Loa Loa (eye worm) hypothetical protein 0.055 0.2549 1
Trichomonas vaginalis modulator of drug activity B, putative 0.0136 0.0618 0.0607
Schistosoma mansoni Tr4/Tr2 (homologue) 0.001 0.0028 0.0109
Loa Loa (eye worm) TK protein kinase 0.055 0.2549 1
Echinococcus multilocularis mothers against decapentaplegic 5 0.0008 0.0019 0.0061
Schistosoma mansoni nuclear receptor 0.0005 0.0003 0.0012
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0275 0.1077
Onchocerca volvulus 0.0005 0.0003 0.0000042611
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0029 0.0117 0.0197
Echinococcus multilocularis activin receptor type 0.055 0.2549 0.9998
Trichomonas vaginalis TKL family protein kinase 0.055 0.2549 0.254
Brugia malayi Low-density lipoprotein receptor-related protein, putative 0.0005 0.0003 0.0005
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0028 0.0102
Echinococcus granulosus tyrosine protein kinase Btk29A 0.055 0.2549 0.9998
Brugia malayi Nuclear hormone receptor-like 1 0.0005 0.0006 0.0015
Trichomonas vaginalis modulator of drug activity B, putative 0.0136 0.0618 0.0607
Echinococcus granulosus protein kinase 0.055 0.2549 0.9998
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.055 0.2549 0.9998
Echinococcus granulosus 6 phosphofructokinase 0.0108 0.0485 0.1891
Entamoeba histolytica tyrosine kinase, putative 0.055 0.2549 0.9998
Entamoeba histolytica protein kinase domain containing protein 0.055 0.2549 0.9998
Echinococcus multilocularis tyrosine protein kinase Src64B 0.055 0.2549 0.9998
Entamoeba histolytica serine/threonine kinase, putative 0.055 0.2549 0.9998
Echinococcus multilocularis protein kinase 0.055 0.2549 0.9998
Schistosoma mansoni src-type protein tyrosine kinase-related 0.055 0.2549 0.9998
Schistosoma mansoni smad 0.0008 0.0019 0.0073
Trichomonas vaginalis modulator of drug activity B, putative 0.0136 0.0618 0.0607
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.055 0.2549 0.254
Trichomonas vaginalis TKL family protein kinase 0.055 0.2549 0.254
Loa Loa (eye worm) TK/INSR protein kinase 0.055 0.2549 1
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0117 0.5
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0029 0.0117 0.0197
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0068 0.0255
Schistosoma mansoni hypothetical protein 0.0078 0.0344 0.135
Trichomonas vaginalis TKL family protein kinase 0.055 0.2549 0.254
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0151 0.014
Trichomonas vaginalis conserved hypothetical protein 0.0136 0.0618 0.0607
Brugia malayi MH2 domain containing protein 0.0118 0.0534 0.209
Trichomonas vaginalis TKL family protein kinase 0.055 0.2549 0.254
Trichomonas vaginalis conserved hypothetical protein 0.0136 0.0618 0.0607
Brugia malayi Protein kinase domain containing protein 0.055 0.2549 1
Trichomonas vaginalis TKL family protein kinase 0.055 0.2549 0.254
Trichomonas vaginalis conserved hypothetical protein 0.0136 0.0618 0.0607
Brugia malayi RNA binding protein 0.0063 0.0275 0.1071
Entamoeba histolytica serine/threonine kinase, putative 0.055 0.2549 0.9998
Schistosoma mansoni inositol monophosphatase 0.0036 0.0151 0.0594
Trichomonas vaginalis TKL family protein kinase 0.055 0.2549 0.254
Trichomonas vaginalis conserved hypothetical protein 0.0136 0.0618 0.0607
Echinococcus granulosus basement membrane specific heparan sulfate 0.0005 0.0003 0.0000042602
Echinococcus multilocularis tyrosine protein kinase ABL1 0.055 0.2549 0.9998
Schistosoma mansoni hypothetical protein 0.0404 0.1867 0.7325
Loa Loa (eye worm) TK/Met protein kinase 0.055 0.2549 1
Brugia malayi SRC-1 0.055 0.2549 1
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.055 0.2549 0.9998
Entamoeba histolytica protein kinase, putative 0.055 0.2549 0.9998
Loa Loa (eye worm) hypothetical protein 0.0005 0.0003 0.0005
Onchocerca volvulus 0.015 0.0681 0.2664
Loa Loa (eye worm) TK/FER protein kinase 0.055 0.2549 1
Entamoeba histolytica hypothetical protein 0.055 0.2549 0.9998
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.055 0.2549 0.9998
Schistosoma mansoni hypothetical protein 0.0005 0.0003 0.0012
Brugia malayi ecdysteroid receptor 0.001 0.0028 0.0102
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.001 0.0028 0.0102
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0485 0.0474
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.055 0.2549 0.9998
Entamoeba histolytica protein kinase, putative 0.055 0.2549 0.9998
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0028 0.0102
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0008 0.0019 0.0073
Trichomonas vaginalis conserved hypothetical protein 0.0136 0.0618 0.0607
Loa Loa (eye worm) hypothetical protein 0.055 0.2549 1
Echinococcus multilocularis tyrosine kinase 0.055 0.2549 0.9998
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.055 0.2549 0.9998
Brugia malayi Protein kinase domain containing protein 0.055 0.2549 1
Loa Loa (eye worm) hypothetical protein 0.0005 0.0006 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.055 0.2549 0.254
Onchocerca volvulus Terribly reduced optic lobes homolog 0.0005 0.0003 0.0000042611
Brugia malayi Protein kinase domain containing protein 0.055 0.2549 1
Trichomonas vaginalis TKL family protein kinase 0.055 0.2549 0.254
Loa Loa (eye worm) TK/FER protein kinase 0.055 0.2549 1
Brugia malayi basement membrane proteoglycan precursor 0.0005 0.0003 0.0005
Trichomonas vaginalis TKL family protein kinase 0.055 0.2549 0.254
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0151 0.0335
Brugia malayi Protein kinase domain containing protein 0.055 0.2549 1
Echinococcus granulosus geminin 0.0168 0.0766 0.2997
Trichomonas vaginalis TKL family protein kinase 0.055 0.2549 0.254
Entamoeba histolytica protein kinase, putative 0.055 0.2549 0.9998
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.055 0.2549 0.9998
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.0485 0.1679
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0005 0.0003 0.0000042611
Loa Loa (eye worm) hypothetical protein 0.0005 0.0003 0.0005
Schistosoma mansoni tyrosine kinase 0.055 0.2549 0.9998
Echinococcus multilocularis tyrosine protein kinase Src42A 0.055 0.2549 0.9998
Schistosoma mansoni ap endonuclease 0.0019 0.0068 0.0267
Brugia malayi Immunoglobulin I-set domain containing protein 0.055 0.2549 1
Entamoeba histolytica tyrosine kinase, putative 0.055 0.2549 0.9998
Brugia malayi Protein kinase domain containing protein 0.055 0.2549 1
Trichomonas vaginalis TKL family protein kinase 0.055 0.2549 0.254
Brugia malayi Probable tyrosine-protein kinase kin-31 0.055 0.2549 1
Schistosoma mansoni protein tyrosine kinase 0.055 0.2549 0.9998
Trichomonas vaginalis TKL family protein kinase 0.055 0.2549 0.254
Trichomonas vaginalis conserved hypothetical protein 0.055 0.2549 0.254
Echinococcus multilocularis tyrosine protein kinase Abl 0.055 0.2549 0.9998
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0108 0.0485 0.1679
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0028 0.0097
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0005 0.0003 0.0012
Loa Loa (eye worm) TK/FER protein kinase 0.055 0.2549 1
Schistosoma mansoni hypothetical protein 0.0005 0.0003 0.0012
Brugia malayi Latrophilin receptor protein 2 0.0036 0.0149 0.0578
Trichomonas vaginalis TKL family protein kinase 0.055 0.2549 0.254
Schistosoma mansoni ap endonuclease 0.0019 0.0068 0.0267
Loa Loa (eye worm) MH2 domain-containing protein 0.0008 0.0019 0.0066
Echinococcus multilocularis tyrosine protein kinase Fyn 0.055 0.2549 0.9998
Trichomonas vaginalis TKL family protein kinase 0.055 0.2549 0.254
Entamoeba histolytica tyrosine kinase, putative 0.055 0.2549 0.9998
Schistosoma mansoni tyrosine kinase 0.055 0.2549 0.9998
Brugia malayi Nuclear hormone receptor-like 1 0.001 0.0028 0.0102
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.055 0.2549 0.9998
Loa Loa (eye worm) low-density lipoprotein receptor domain class A containing protein 0.0005 0.0003 0.0005
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.055 0.2549 0.9998
Entamoeba histolytica modulator of drug activity B homolog, putative 0.0136 0.0618 0.2215
Echinococcus multilocularis protein kinase 0.055 0.2549 0.9998
Schistosoma mansoni tyrosine kinase 0.055 0.2549 0.9998
Plasmodium falciparum tyrosine kinase-like protein 0.055 0.2549 1
Loa Loa (eye worm) steroid hormone receptor 0.001 0.0028 0.0102
Loa Loa (eye worm) MH2 domain-containing protein 0.0118 0.0534 0.209
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.0485 0.1679
Echinococcus granulosus activated cdc42 kinase 1 0.055 0.2549 0.9998
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.055 0.2549 1
Schistosoma mansoni ephrin receptor 0.055 0.2549 0.9998
Loa Loa (eye worm) TK protein kinase 0.055 0.2549 1
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.055 0.2549 1
Brugia malayi conserved hypotetical protein 0.0005 0.0003 0.0005
Echinococcus multilocularis tyrosine protein kinase csk 0.055 0.2549 0.9998
Trichomonas vaginalis conserved hypothetical protein 0.0136 0.0618 0.0607
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0005 0.0006 0.001
Brugia malayi Protein kinase domain containing protein 0.055 0.2549 1
Loa Loa (eye worm) TK/FER protein kinase 0.055 0.2549 1
Trichomonas vaginalis TKL family protein kinase 0.055 0.2549 0.254
Echinococcus granulosus tyrosine protein kinase Blk 0.055 0.2549 0.9998
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.001 0.0028 0.0109
Echinococcus multilocularis epidermal growth factor receptor 0.055 0.2549 0.9998
Brugia malayi Low-density lipoprotein receptor domain class A containing protein 0.0005 0.0003 0.0005
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0151 0.014
Loa Loa (eye worm) hypothetical protein 0.0005 0.0003 0.0005
Loa Loa (eye worm) TK/FER protein kinase 0.055 0.2549 1
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0151 0.0335
Echinococcus granulosus low density lipoprotein receptor protein 0.0005 0.0003 0.0000042602
Schistosoma mansoni hypothetical protein 0.0036 0.0149 0.0585
Brugia malayi Nuclear hormone receptor family member nhr-1 0.001 0.0028 0.0102
Entamoeba histolytica protein kinase, putative 0.055 0.2549 1
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.055 0.2549 1
Entamoeba histolytica iron-sulfur flavoprotein, putative 0.0136 0.0618 0.2215
Loa Loa (eye worm) hypothetical protein 0.001 0.0028 0.0102
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.055 0.2549 0.9998
Brugia malayi Protein kinase domain containing protein 0.055 0.2549 1
Trichomonas vaginalis TKL family protein kinase 0.055 0.2549 0.254
Schistosoma mansoni hypothetical protein 0.0168 0.0766 0.3005
Echinococcus multilocularis transfer RNA-Thr 0.055 0.2549 0.9998
Loa Loa (eye worm) TK/EPH protein kinase 0.055 0.2549 1
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0485 0.0474
Trichomonas vaginalis TKL family protein kinase 0.055 0.2549 0.254
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0007 0.0014 0.0042
Entamoeba histolytica protein kinase, putative 0.055 0.2549 0.9998
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0005 0.0003 0.0012
Trichomonas vaginalis NAD(P)H dehydrogenase, putative 0.0136 0.0618 0.0607
Loa Loa (eye worm) low-density lipoprotein receptor domain class A containing protein 0.0005 0.0003 0.0005
Brugia malayi TAR-binding protein 0.0063 0.0275 0.1071
Loa Loa (eye worm) TK protein kinase 0.055 0.2549 1
Loa Loa (eye worm) TK/DDR protein kinase 0.055 0.2549 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.055 0.2549 0.9998
Entamoeba histolytica tyrosine kinase, putative 0.055 0.2549 0.9998
Trichomonas vaginalis protein tyrosine kinase, putative 0.055 0.2549 0.254
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0108 0.0485 0.1679
Leishmania major ATP-dependent phosphofructokinase 0.0108 0.0485 0.1679
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.001 0.0028 0.0097
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.055 0.2549 0.9998
Entamoeba histolytica protein kinase domain containing protein 0.055 0.2549 0.9998
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.055 0.2549 0.9998
Loa Loa (eye worm) TK/ABL protein kinase 0.055 0.2549 1
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0008 0.0019 0.0061
Loa Loa (eye worm) hypothetical protein 0.0005 0.0003 0.0005
Trichomonas vaginalis TKL family protein kinase 0.055 0.2549 0.254
Plasmodium vivax tyrosine kinase-like protein, putative 0.055 0.2549 1
Loa Loa (eye worm) DR-78 0.0005 0.0003 0.0005
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.055 0.2549 0.9998
Schistosoma mansoni protein kinase 0.055 0.2549 0.9998
Leishmania major protein kinase, putative 0.055 0.2549 1
Brugia malayi Protein kinase domain containing protein 0.055 0.2549 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.055 0.2549 0.9998
Schistosoma mansoni 6-phosphofructokinase 0.0108 0.0485 0.1901
Mycobacterium ulcerans 6-phosphofructokinase 0.0108 0.0485 1
Trichomonas vaginalis TKL family protein kinase 0.055 0.2549 0.254
Echinococcus granulosus tyrosine protein kinase csk 0.055 0.2549 0.9998
Echinococcus granulosus kinase suppressor of Ras 1 0.055 0.2549 0.9998
Brugia malayi Low-density lipoprotein receptor domain class A containing protein 0.0005 0.0003 0.0005
Onchocerca volvulus 0.055 0.2549 1
Loa Loa (eye worm) hypothetical protein 0.0005 0.0003 0.0005
Loa Loa (eye worm) 6-phosphofructokinase 0.0108 0.0485 0.1896
Loa Loa (eye worm) hypothetical protein 0.001 0.0028 0.0102
Loa Loa (eye worm) hypothetical protein 0.055 0.2549 1
Brugia malayi MH2 domain containing protein 0.0008 0.0019 0.0066
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.001 0.0028 0.0102
Schistosoma mansoni tyrosine kinase 0.055 0.2549 0.9998
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.055 0.2549 0.9998
Entamoeba histolytica receptor protein kinase, putative 0.055 0.2549 0.9998
Schistosoma mansoni 6-phosphofructokinase 0.0108 0.0485 0.1901
Entamoeba histolytica tyrosine kinase, putative 0.055 0.2549 0.9998
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0028 0.0102
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.055 0.2549 0.9998
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0485 0.0474
Trichomonas vaginalis TKL family protein kinase 0.055 0.2549 0.254
Brugia malayi Protein kinase domain containing protein 0.055 0.2549 1
Echinococcus granulosus receptor type guanylyl cyclase 0.055 0.2549 0.9998
Trichomonas vaginalis NAD(P)H dehydrogenase, putative 0.2145 1 1
Echinococcus multilocularis activated cdc42 kinase 1 0.055 0.2549 0.9998
Trichomonas vaginalis modulator of drug activity B, putative 0.0136 0.0618 0.0607
Loa Loa (eye worm) TK/RYK protein kinase 0.055 0.2549 1
Onchocerca volvulus 0.055 0.2549 1
Onchocerca volvulus 0.055 0.2549 1
Brugia malayi nuclear receptor NHR-88 0.001 0.0028 0.0102
Loa Loa (eye worm) TK/ALK protein kinase 0.055 0.2549 1
Echinococcus multilocularis low density lipoprotein receptor (ldl) 0.0005 0.0003 0.0000042602
Trichomonas vaginalis conserved hypothetical protein 0.0136 0.0618 0.0607
Loa Loa (eye worm) TK/FER protein kinase 0.055 0.2549 1
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0117 0.0197
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0068 0.0057
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.055 0.2549 0.9998
Trichomonas vaginalis TKL family protein kinase 0.055 0.2549 0.254
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0117 0.0197
Onchocerca volvulus 0.055 0.2549 1
Trichomonas vaginalis TKL family protein kinase 0.055 0.2549 0.254
Entamoeba histolytica hypothetical protein 0.055 0.2549 1
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0068 0.0255
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.055 0.2549 0.9998
Toxoplasma gondii histone lysine methyltransferase SET1 0.0054 0.0232 0.066
Schistosoma mansoni hypothetical protein 0.0168 0.0766 0.3005
Entamoeba histolytica serine/threonine kinase, putative 0.055 0.2549 0.9998
Echinococcus granulosus retinal guanylyl cyclase 2 0.055 0.2549 0.9998
Entamoeba histolytica protein kinase domain containing protein 0.055 0.2549 0.9998
Echinococcus multilocularis insulin receptor 0.055 0.2549 0.9998
Echinococcus multilocularis tyrosine protein kinase csk 0.055 0.2549 0.9998
Loa Loa (eye worm) hypothetical protein 0.0005 0.0003 0.0005
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.055 0.2549 0.9998
Echinococcus multilocularis kinase suppressor of Ras 1 0.055 0.2549 0.9998
Schistosoma mansoni protein kinase 0.055 0.2549 0.9998
Brugia malayi Protein kinase domain containing protein 0.055 0.2549 1
Echinococcus granulosus epidermal growth factor receptor 0.055 0.2549 0.9998
Entamoeba histolytica hypothetical protein 0.055 0.2549 0.9998
Echinococcus granulosus tyrosine protein kinase Btk29A 0.055 0.2549 0.9998
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0275 0.1077
Trichomonas vaginalis TKL family protein kinase 0.055 0.2549 0.254
Schistosoma mansoni tyrosine protein kinase 0.055 0.2549 0.9998
Schistosoma mansoni tyrosine kinase 0.055 0.2549 0.9998
Trichomonas vaginalis conserved hypothetical protein 0.0136 0.0618 0.0607
Entamoeba histolytica protein kinase, putative 0.055 0.2549 0.9998
Brugia malayi hypothetical protein 0.055 0.2549 1
Brugia malayi nuclear receptor RXR 0.0005 0.0006 0.0015
Trichomonas vaginalis TKL family protein kinase 0.055 0.2549 0.254
Trichomonas vaginalis conserved hypothetical protein 0.055 0.2549 0.254
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.055 0.2549 0.9998
Trichomonas vaginalis TKL family protein kinase 0.055 0.2549 0.254
Echinococcus granulosus tyrosine kinase 0.055 0.2549 0.9998
Schistosoma mansoni cpg binding protein 0.003 0.0121 0.0475
Echinococcus granulosus mixed lineage leukemia protein mll 0.0007 0.0014 0.0042
Echinococcus multilocularis low density lipoprotein receptor protein 0.0005 0.0003 0.0000042602
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0007 0.0014 0.0042
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0009 0.0022 0.0074
Schistosoma mansoni tyrosine kinase 0.055 0.2549 0.9998
Echinococcus multilocularis c src tyrosine kinase 0.055 0.2549 0.9998
Brugia malayi hypothetical protein 0.015 0.0681 0.2667
Trichomonas vaginalis modulator of drug activity B, putative 0.0136 0.0618 0.0607
Loa Loa (eye worm) nuclear receptor NHR-67 0.0005 0.0003 0.0005
Entamoeba histolytica protein kinase domain containing protein 0.055 0.2549 0.9998
Brugia malayi Protein kinase domain containing protein 0.055 0.2549 1
Loa Loa (eye worm) hypothetical protein 0.0114 0.0512 0.2005
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.055 0.2549 1
Entamoeba histolytica hypothetical protein 0.055 0.2549 0.9998
Trypanosoma cruzi protein kinase, putative 0.055 0.2549 1
Loa Loa (eye worm) TK/FER protein kinase 0.055 0.2549 1
Echinococcus granulosus tyrosine protein kinase HCK 0.055 0.2549 0.9998
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0005 0.0003 0.0012
Entamoeba histolytica protein kinase, putative 0.055 0.2549 0.9998
Echinococcus granulosus tyrosine protein kinase csk 0.055 0.2549 0.9998
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.001 0.0028 0.0097
Brugia malayi Low-density lipoprotein receptor domain class A containing protein 0.0005 0.0003 0.0005
Schistosoma mansoni protein kinase 0.055 0.2549 0.9998
Echinococcus granulosus tyrosine protein kinase pr2 0.055 0.2549 0.9998
Entamoeba histolytica protein kinase, putative 0.055 0.2549 0.9998
Loa Loa (eye worm) hypothetical protein 0.055 0.2549 1
Echinococcus multilocularis heat shock protein 70 0.055 0.2549 0.9998
Schistosoma mansoni hypothetical protein 0.0028 0.0114 0.0447
Trichomonas vaginalis TKL family protein kinase 0.055 0.2549 0.254
Trichomonas vaginalis TKL family protein kinase 0.055 0.2549 0.254
Echinococcus multilocularis dual specificity testis specific protein kinase 0.055 0.2549 0.9998
Schistosoma mansoni thyroid hormone receptor 0.001 0.0028 0.0109
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.001 0.0028 0.0109
Loa Loa (eye worm) hypothetical protein 0.001 0.0028 0.0102
Trichomonas vaginalis TKL family protein kinase 0.055 0.2549 0.254
Trichomonas vaginalis TKL family protein kinase 0.055 0.2549 0.254
Brugia malayi Protein kinase domain containing protein 0.055 0.2549 1
Echinococcus granulosus tyrosine protein kinase shark 0.055 0.2549 1
Entamoeba histolytica protein kinase domain containing protein 0.055 0.2549 0.9998
Entamoeba histolytica tyrosin kinase, putative 0.055 0.2549 0.9998
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0151 0.014
Schistosoma mansoni tyrosine kinase 0.055 0.2549 0.9998
Schistosoma mansoni retinoid-x-receptor (RXR) 0.001 0.0028 0.0109
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0005 0.0006 0.0023
Entamoeba histolytica serine/threonine kinase, putative 0.055 0.2549 0.9998
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0009 0.0022 0.0074
Trichomonas vaginalis TKL family protein kinase 0.055 0.2549 0.254
Entamoeba histolytica tyrosine kinase, putative 0.055 0.2549 0.9998
Loa Loa (eye worm) hypothetical protein 0.0028 0.0114 0.044
Loa Loa (eye worm) hypothetical protein 0.0078 0.0344 0.1344
Schistosoma mansoni serine/threonine protein kinase 0.055 0.2549 0.9998
Entamoeba histolytica serine/threonine kinase, putative 0.055 0.2549 0.9998
Echinococcus granulosus death domain containing protein 0.0028 0.0114 0.0435
Loa Loa (eye worm) hypothetical protein 0.0005 0.0003 0.0005
Brugia malayi Nuclear hormone receptor family member nhr-41 0.001 0.0028 0.0102
Loa Loa (eye worm) 6-phosphofructokinase 0.0108 0.0485 0.1896
Loa Loa (eye worm) hypothetical protein 0.001 0.0028 0.0102
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.055 0.2549 0.9998
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0117 0.0106
Schistosoma mansoni serine/threonine RGC 0.055 0.2549 0.9998
Echinococcus granulosus tyrosine protein kinase Fps85D 0.055 0.2549 0.9998
Loa Loa (eye worm) hypothetical protein 0.0005 0.0003 0.0005
Toxoplasma gondii phosphofructokinase PFKII 0.0029 0.0117 0.0197
Onchocerca volvulus 0.0028 0.0113 0.0434
Trichomonas vaginalis conserved hypothetical protein 0.055 0.2549 0.254
Schistosoma mansoni tyrosine-protein kinase fps85d 0.055 0.2549 0.9998
Trichomonas vaginalis TKL family protein kinase 0.055 0.2549 0.254
Loa Loa (eye worm) inositol-1 0.0036 0.0151 0.0587
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.055 0.2549 0.9998
Trichomonas vaginalis modulator of drug activity B, putative 0.0136 0.0618 0.0607
Loa Loa (eye worm) TK/FER protein kinase 0.055 0.2549 1
Brugia malayi Calcitonin receptor-like protein seb-1 0.0114 0.0512 0.2005
Echinococcus granulosus tyrosine protein kinase 0.055 0.2549 0.9998
Echinococcus multilocularis tyrosine protein kinase Fyn 0.055 0.2549 0.9998
Schistosoma mansoni nuclear hormone receptor 0.0005 0.0003 0.0012
Brugia malayi hypothetical protein 0.0005 0.0006 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.0136 0.0618 0.0607
Entamoeba histolytica tyrosine kinase, putative 0.055 0.2549 0.9998
Trichomonas vaginalis TKL family protein kinase 0.055 0.2549 0.254
Loa Loa (eye worm) TAR-binding protein 0.0063 0.0275 0.1071
Brugia malayi Protein kinase domain containing protein 0.055 0.2549 1
Trichomonas vaginalis TKL family protein kinase 0.055 0.2549 0.254
Loa Loa (eye worm) TK/FER protein kinase 0.055 0.2549 1
Plasmodium falciparum protein kinase, putative 0.055 0.2549 1
Schistosoma mansoni tyrosine kinase 0.055 0.2549 0.9998
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.055 0.2549 0.9998
Brugia malayi Nuclear hormone receptor E75 0.0005 0.0003 0.0005
Echinococcus multilocularis thyroid hormone receptor alpha 0.001 0.0028 0.0097
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.001 0.0028 0.0097
Schistosoma mansoni tyrosine kinase 0.055 0.2549 0.9998
Echinococcus multilocularis geminin 0.0168 0.0766 0.2997
Entamoeba histolytica tyrosine kinase, putative 0.055 0.2549 0.9998
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.055 0.2549 0.9998
Trichomonas vaginalis TKL family protein kinase 0.055 0.2549 0.254
Loa Loa (eye worm) hypothetical protein 0.0005 0.0006 0.0015
Brugia malayi F/Y-rich N-terminus family protein 0.0009 0.0021 0.0077
Trichomonas vaginalis conserved hypothetical protein 0.0136 0.0618 0.0607
Echinococcus granulosus FTZ F1 alpha 0.001 0.0028 0.0097
Brugia malayi Tyrosine-protein kinase abl-1 0.055 0.2549 1
Onchocerca volvulus Bile acid receptor homolog 0.001 0.0028 0.0097
Onchocerca volvulus 0.0005 0.0003 0.0000042611
Onchocerca volvulus Arrow homolog 0.0005 0.0003 0.0000042611
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.055 0.2549 1
Brugia malayi Guanylyl cyclase protein 23 0.055 0.2549 1
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0117 0.0106
Loa Loa (eye worm) latrophilin receptor protein 2 0.0036 0.0149 0.0578
Trichomonas vaginalis protein kinase atn1, putative 0.055 0.2549 0.254
Echinococcus multilocularis tyrosine protein kinase csk 0.055 0.2549 0.9998
Schistosoma mansoni netrin receptor unc5 0.0028 0.0114 0.0447
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0007 0.0014 0.0055
Echinococcus multilocularis tar DNA binding protein 0.0063 0.0275 0.1066
Schistosoma mansoni tyrosine kinase 0.055 0.2549 0.9998
Echinococcus multilocularis natriuretic peptide receptor 1 0.055 0.2549 0.9998
Toxoplasma gondii protein kinase 0.055 0.2549 1
Schistosoma mansoni hypothetical protein 0.0036 0.0149 0.0585
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0117 0.0106
Echinococcus granulosus tyrosine protein kinase csk 0.055 0.2549 0.9998
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0028 0.0102
Onchocerca volvulus 0.055 0.2549 1
Schistosoma mansoni tyrosine kinase 0.055 0.2549 0.9998
Schistosoma mansoni steroid hormone receptor ad4bp 0.001 0.0028 0.0109
Loa Loa (eye worm) hypothetical protein 0.001 0.0028 0.0102
Loa Loa (eye worm) histone methyltransferase 0.0009 0.0022 0.0079
Trichomonas vaginalis STE family protein kinase 0.055 0.2549 0.254
Giardia lamblia NADPH oxidoreductase, putative 0.0136 0.0618 0.2215
Loa Loa (eye worm) hypothetical protein 0.015 0.0681 0.2667
Brugia malayi Nuclear hormone receptor family member nhr-31 0.001 0.0028 0.0102
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.055 0.2549 1
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.055 0.2549 1
Trichomonas vaginalis conserved hypothetical protein 0.0136 0.0618 0.0607
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0068 0.026
Loa Loa (eye worm) hypothetical protein 0.0005 0.0003 0.0005
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0113 0.0438
Brugia malayi MH1 domain containing protein 0.0008 0.0019 0.0066
Onchocerca volvulus 0.055 0.2549 1
Brugia malayi ecdysone receptor 0.0005 0.0003 0.0005
Trichomonas vaginalis TKL family protein kinase 0.055 0.2549 0.254
Brugia malayi Protein kinase domain containing protein 0.055 0.2549 1
Trichomonas vaginalis TKL family protein kinase 0.055 0.2549 0.254
Brugia malayi protein-tyrosine kinase 0.055 0.2549 1
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0036 0.0149 0.0574
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.055 0.2549 0.9998
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0036 0.0149 0.0574
Entamoeba histolytica hypothetical protein 0.055 0.2549 0.9998
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.001 0.0028 0.0102
Echinococcus multilocularis receptor type guanylyl cyclase 0.055 0.2549 0.9998
Schistosoma mansoni coup transcription factor 0.001 0.0028 0.0109
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.055 0.2549 0.9998
Loa Loa (eye worm) hypothetical protein 0.0005 0.0003 0.0005
Brugia malayi hypothetical protein 0.055 0.2549 1
Entamoeba histolytica protein kinase domain containing protein 0.055 0.2549 0.9998
Loa Loa (eye worm) hypothetical protein 0.055 0.2549 1
Trichomonas vaginalis NAD(P)H dehydrogenase, putative 0.0136 0.0618 0.0607
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.055 0.2549 0.9998
Schistosoma mansoni tyrosine kinase 0.055 0.2549 0.9998
Echinococcus granulosus insulin receptor 0.055 0.2549 0.9998
Brugia malayi SH2 domain containing protein 0.055 0.2549 1
Brugia malayi SH2 domain containing protein 0.055 0.2549 1
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0117 0.0197
Schistosoma mansoni protein kinase 0.055 0.2549 1
Schistosoma mansoni protein kinase 0.055 0.2549 0.9998
Schistosoma mansoni tyrosine kinase 0.055 0.2549 0.9998
Giardia lamblia Protein 21.1 0.055 0.2549 0.9998
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0005 0.0003 0.0005
Echinococcus multilocularis smad 0.0008 0.0019 0.0061
Trichomonas vaginalis TKL family protein kinase 0.055 0.2549 0.254
Echinococcus granulosus tar DNA binding protein 0.0063 0.0275 0.1066
Loa Loa (eye worm) TK/EGFR protein kinase 0.055 0.2549 1
Echinococcus granulosus smad 0.0008 0.0019 0.0061
Brugia malayi Nuclear hormone receptor family member nhr-40 0.001 0.0028 0.0102
Trichomonas vaginalis TKL family protein kinase 0.055 0.2549 0.254
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.055 0.2549 1
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.055 0.2549 0.254
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0275 0.1077
Trichomonas vaginalis modulator of drug activity B, putative 0.0136 0.0618 0.0607
Trichomonas vaginalis TKL family protein kinase 0.055 0.2549 0.254
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.001 0.0028 0.0097
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.001 0.0028 0.0109
Toxoplasma gondii STE kinase 0.055 0.2549 1
Trypanosoma brucei protein kinase, putative 0.055 0.2549 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0114 0.0512 0.2005
Entamoeba histolytica protein kinase domain containing protein 0.055 0.2549 0.9998
Trichomonas vaginalis TKL family protein kinase 0.055 0.2549 0.254
Echinococcus granulosus Low density lipoprotein receptor class A cysteine rich 0.0005 0.0003 0.0000042602
Trichomonas vaginalis modulator of drug activity B, putative 0.0136 0.0618 0.0607
Onchocerca volvulus 0.055 0.2549 1
Brugia malayi Calcium binding EGF domain containing protein 0.0005 0.0003 0.0005
Trichomonas vaginalis TKL family protein kinase 0.055 0.2549 0.254
Entamoeba histolytica protein kinase, putative 0.055 0.2549 0.9998
Loa Loa (eye worm) hypothetical protein 0.055 0.2549 1
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.055 0.2549 1
Loa Loa (eye worm) hypothetical protein 0.055 0.2549 1
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0005 0.0006 0.001
Echinococcus granulosus integrin linked protein kinase 0.055 0.2549 0.9998
Trichomonas vaginalis NAD(P)H dehydrogenase, putative 0.0136 0.0618 0.0607
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0029 0.0117 0.0106
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0028 0.0102
Schistosoma mansoni tyrosine kinase 0.055 0.2549 1
Loa Loa (eye worm) TK/KIN16 protein kinase 0.055 0.2549 1
Loa Loa (eye worm) hypothetical protein 0.0005 0.0003 0.0005
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.055 0.2549 1
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0117 0.0106
Loa Loa (eye worm) TK/FER protein kinase 0.055 0.2549 1
Trichomonas vaginalis TKL family protein kinase 0.055 0.2549 0.254
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0005 0.0003 0.0000042602
Trichomonas vaginalis TKL family protein kinase 0.055 0.2549 0.254
Trichomonas vaginalis TKL family protein kinase 0.055 0.2549 0.254
Brugia malayi Protein kinase domain containing protein 0.055 0.2549 1
Loa Loa (eye worm) TK protein kinase 0.055 0.2549 1
Brugia malayi hypothetical protein 0.055 0.2549 1
Schistosoma mansoni thyroid hormone receptor 0.001 0.0028 0.0109
Leishmania major protein kinase, putative 0.055 0.2549 1
Brugia malayi integrin-linked kinase 0.055 0.2549 1
Onchocerca volvulus 0.055 0.2549 1
Schistosoma mansoni nuclear receptor nhr-48 0.0005 0.0003 0.0012
Trichomonas vaginalis TKL family protein kinase 0.055 0.2549 0.254
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0278 0.128 0.5015
Echinococcus granulosus GPCR family 2 0.0036 0.0149 0.0574
Brugia malayi MH2 domain containing protein 0.0008 0.0019 0.0066
Brugia malayi nuclear receptor NHR-67 0.0005 0.0003 0.0005
Loa Loa (eye worm) serine/threonine protein kinase 0.055 0.2549 1
Trichomonas vaginalis modulator of drug activity B, putative 0.0136 0.0618 0.0607
Brugia malayi Probable tyrosine-protein kinase kin-31 0.055 0.2549 1
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0068 0.026
Entamoeba histolytica protein kinase domain containing protein 0.055 0.2549 0.9998
Echinococcus granulosus retinal guanylyl cyclase 2 0.055 0.2549 0.9998
Echinococcus multilocularis tyrosine kinase 0.055 0.2549 0.9998
Brugia malayi Protein kinase domain containing protein 0.0028 0.0114 0.044
Loa Loa (eye worm) nuclear hormone receptor 0.0005 0.0003 0.0005
Entamoeba histolytica hypothetical protein 0.055 0.2549 1
Brugia malayi latrophilin 2 splice variant baaae 0.0078 0.0344 0.1344
Schistosoma mansoni tyrosine kinase 0.055 0.2549 0.9998
Loa Loa (eye worm) hypothetical protein 0.055 0.2549 1
Entamoeba histolytica tyrosine kinase, putative 0.055 0.2549 0.9998
Giardia lamblia Kinase, NEK 0.055 0.2549 1
Echinococcus multilocularis dnaJ subfamily B 0.0404 0.1867 0.7322
Brugia malayi Protein kinase domain containing protein 0.055 0.2549 1
Loa Loa (eye worm) hypothetical protein 0.0005 0.0003 0.0005
Loa Loa (eye worm) TK/FER protein kinase 0.055 0.2549 1
Schistosoma mansoni tyrosine kinase 0.055 0.2549 0.9998
Trichomonas vaginalis modulator of drug activity B, putative 0.0136 0.0618 0.0607
Schistosoma mansoni nuclear receptor 0.0005 0.0003 0.0012
Entamoeba histolytica ankyrin repeat protein 0.055 0.2549 0.9998
Schistosoma mansoni inositol monophosphatase 0.0036 0.0151 0.0594
Echinococcus granulosus tyrosine protein kinase Srms 0.055 0.2549 0.9998
Schistosoma mansoni RAR-like nuclear receptor 0.001 0.0028 0.0109
Trichomonas vaginalis TKL family protein kinase 0.055 0.2549 0.254
Brugia malayi Low-density lipoprotein receptor domain class A containing protein 0.0005 0.0003 0.0005
Onchocerca volvulus 0.055 0.2549 1
Echinococcus granulosus basement membrane specific heparan sulfate 0.0005 0.0003 0.0000042602
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0108 0.0485 1
Entamoeba histolytica protein kinase domain containing protein 0.055 0.2549 0.9998
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.055 0.2549 0.9998
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.055 0.2549 1
Trichomonas vaginalis conserved hypothetical protein 0.0136 0.0618 0.0607
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0005 0.0003 0.0012
Entamoeba histolytica tyrosine kinase, putative 0.055 0.2549 0.9998
Schistosoma mansoni cpg binding protein 0.0028 0.0113 0.0445
Giardia lamblia Kinase 0.055 0.2549 0.9998
Trypanosoma brucei RNA helicase, putative 0.0085 0.0377 0.1245
Brugia malayi enteropeptidase precursor 0.0005 0.0003 0.0005
Brugia malayi Immunoglobulin I-set domain containing protein 0.0028 0.0114 0.044
Trichomonas vaginalis TKL family protein kinase 0.055 0.2549 0.254
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0028 0.0114 0.0435
Loa Loa (eye worm) TK protein kinase 0.055 0.2549 1
Echinococcus granulosus cpg binding protein 0.003 0.0121 0.0463
Echinococcus granulosus mothers against decapentaplegic 5 0.0008 0.0019 0.0061
Loa Loa (eye worm) phosphofructokinase 0.0108 0.0485 0.1896
Brugia malayi RNA recognition motif domain containing protein 0.0063 0.0275 0.1071
Brugia malayi Protein kinase domain containing protein 0.055 0.2549 1
Trichomonas vaginalis TKL family protein kinase 0.055 0.2549 0.254
Echinococcus multilocularis tyrosine protein kinase HCK 0.055 0.2549 0.9998
Echinococcus multilocularis low density lipoprotein receptor (ldl) 0.0005 0.0003 0.0000042602
Schistosoma mansoni hypothetical protein 0.0036 0.0149 0.0585
Schistosoma mansoni nuclear hormone receptor 0.001 0.0028 0.0109
Loa Loa (eye worm) TK protein kinase 0.055 0.2549 1
Echinococcus multilocularis protein KINase family member (kin 25) 0.055 0.2549 0.9998
Trypanosoma brucei Pseudokinase, putative 0.055 0.2549 1
Loa Loa (eye worm) TK/FER protein kinase 0.055 0.2549 1
Trichomonas vaginalis modulator of drug activity B, putative 0.0136 0.0618 0.0607
Echinococcus multilocularis Ankyrin 0.0029 0.0114 0.0437
Echinococcus multilocularis retinal guanylyl cyclase 2 0.055 0.2549 0.9998
Trichomonas vaginalis FMN-dependent NADH-azoreductase, putative 0.0136 0.0618 0.0607
Brugia malayi nuclear receptor NHR-88 0.0005 0.0003 0.0005
Echinococcus multilocularis tyrosine protein kinase Blk 0.055 0.2549 0.9998

Activities

Activity type Activity value Assay description Source Reference
Inhibition (binding) < 35 % Inhibition of human cathepsin B at 20 uM relative to control ChEMBL. No reference
Inhibition (binding) < 35 % Inhibition of human cathepsin L at 20 uM relative to control ChEMBL. No reference
Ki (binding) Inhibition of human cathepsin B LITERATURE. No reference
Ki (binding) Inhibition of human cathepsin L ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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