Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | MDM2 proto-oncogene, E3 ubiquitin protein ligase | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.038 | 1 | 1 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.038 | 1 | 1 |
Brugia malayi | nuclear receptor NHR-88 | 0.038 | 1 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0201 | 0.1071 | 0.1071 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.038 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0201 | 0.1071 | 0.1071 |
Schistosoma mansoni | nuclear hormone receptor | 0.038 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0201 | 0.1071 | 0.1071 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.038 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.038 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.038 | 1 | 1 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.038 | 1 | 1 |
Onchocerca volvulus | 0.038 | 1 | 1 | |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.038 | 1 | 1 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0201 | 0.1071 | 0.1071 |
Loa Loa (eye worm) | hypothetical protein | 0.0201 | 0.1071 | 0.1071 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.038 | 1 | 1 |
Brugia malayi | nuclear hormone receptor | 0.038 | 1 | 1 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.038 | 1 | 1 |
Onchocerca volvulus | Bile acid receptor homolog | 0.038 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.038 | 1 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.038 | 1 | 1 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.038 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.038 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0201 | 0.1071 | 0.1071 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.038 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.038 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.038 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.038 | 1 | 1 |
Echinococcus granulosus | FTZ F1 alpha | 0.038 | 1 | 1 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0201 | 0.1071 | 0.1071 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.038 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.038 | 1 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.038 | 1 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.038 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.038 | 1 | 1 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.038 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.038 | 1 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.038 | 1 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.038 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.038 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0201 | 0.1071 | 0.1071 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.038 | 1 | 1 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.038 | 1 | 1 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.038 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0201 | 0.1071 | 0.1071 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.038 | 1 | 1 |
Echinococcus multilocularis | FTZ F1 alpha | 0.038 | 1 | 1 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.038 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0201 | 0.1071 | 0.1071 |
Loa Loa (eye worm) | hypothetical protein | 0.038 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0201 | 0.1071 | 0.1071 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.038 | 1 | 1 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.038 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0201 | 0.1071 | 0.1071 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.038 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.038 | 1 | 1 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.038 | 1 | 1 |
Brugia malayi | nuclear receptor RXR | 0.0201 | 0.1071 | 0.1071 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.038 | 1 | 1 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.038 | 1 | 1 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.038 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.038 | 1 | 1 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.038 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0201 | 0.1071 | 0.1071 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.038 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.038 | 1 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.038 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.038 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.038 | 1 | 1 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.038 | 1 | 1 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0201 | 0.1071 | 0.1071 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.038 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.038 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.038 | 1 | 1 |
Schistosoma mansoni | coup transcription factor | 0.038 | 1 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.038 | 1 | 1 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.038 | 1 | 1 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.038 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.038 | 1 | 1 |
Loa Loa (eye worm) | steroid hormone receptor | 0.038 | 1 | 1 |
Brugia malayi | steroid hormone receptor | 0.038 | 1 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.038 | 1 | 1 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.038 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.038 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.