Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0115 | 0.4049 | 0.4049 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0115 | 0.4049 | 0.4049 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0244 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0115 | 0.4049 | 0.4049 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0115 | 0.4049 | 0.4049 |
Brugia malayi | hypothetical protein | 0.0129 | 0.4687 | 0.4687 |
Brugia malayi | nuclear receptor RXR | 0.0129 | 0.4687 | 0.4687 |
Loa Loa (eye worm) | hypothetical protein | 0.0129 | 0.4687 | 0.4687 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0115 | 0.4049 | 0.4049 |
Loa Loa (eye worm) | hypothetical protein | 0.0115 | 0.4049 | 0.4049 |
Brugia malayi | ecdysone receptor | 0.0115 | 0.4049 | 0.4049 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0244 | 1 | 1 |
Onchocerca volvulus | 0.0244 | 1 | 1 | |
Brugia malayi | nuclear hormone receptor | 0.0244 | 1 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0244 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0129 | 0.4687 | 0.4687 |
Loa Loa (eye worm) | hypothetical protein | 0.0115 | 0.4049 | 0.4049 |
Loa Loa (eye worm) | hypothetical protein | 0.0115 | 0.4049 | 0.4049 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0244 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0115 | 0.4049 | 0.4049 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0244 | 1 | 1 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0244 | 1 | 1 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0244 | 1 | 1 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0244 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0115 | 0.4049 | 0.4049 |
Schistosoma mansoni | thyroid hormone receptor | 0.0244 | 1 | 1 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0244 | 1 | 1 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0244 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0244 | 1 | 1 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0115 | 0.4049 | 0.4049 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0244 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0244 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0129 | 0.4687 | 0.4687 |
Brugia malayi | nuclear receptor NHR-88 | 0.0115 | 0.4049 | 0.4049 |
Brugia malayi | nuclear receptor RXR | 0.0115 | 0.4049 | 0.4049 |
Loa Loa (eye worm) | hypothetical protein | 0.0115 | 0.4049 | 0.4049 |
Loa Loa (eye worm) | DR-78 | 0.0115 | 0.4049 | 0.4049 |
Loa Loa (eye worm) | hypothetical protein | 0.0115 | 0.4049 | 0.4049 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0115 | 0.4049 | 0.4049 |
Loa Loa (eye worm) | hypothetical protein | 0.0115 | 0.4049 | 0.4049 |
Loa Loa (eye worm) | hypothetical protein | 0.0115 | 0.4049 | 0.4049 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0244 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0244 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0244 | 1 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.0244 | 1 | 1 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0115 | 0.4049 | 0.4049 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0244 | 1 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0244 | 1 | 1 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0244 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0129 | 0.4687 | 0.4687 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0129 | 0.4687 | 0.1071 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0244 | 1 | 1 |
Leishmania major | cytochrome p450-like protein | 0.0027 | 0 | 0.5 |
Echinococcus granulosus | FTZ F1 alpha | 0.0244 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0244 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0244 | 1 | 1 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0027 | 0 | 0.5 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0244 | 1 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0244 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0129 | 0.4687 | 0.4687 |
Loa Loa (eye worm) | hypothetical protein | 0.0129 | 0.4687 | 0.4687 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0115 | 0.4049 | 0.4049 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0244 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0244 | 1 | 1 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0244 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0244 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0115 | 0.4049 | 0.4049 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0244 | 1 | 1 |
Brugia malayi | conserved hypotetical protein | 0.0115 | 0.4049 | 0.4049 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0244 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0244 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0244 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0244 | 1 | 1 |
Brugia malayi | nuclear receptor NHR-67 | 0.0115 | 0.4049 | 0.4049 |
Loa Loa (eye worm) | hypothetical protein | 0.0129 | 0.4687 | 0.4687 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0244 | 1 | 1 |
Brugia malayi | steroid hormone receptor | 0.0244 | 1 | 1 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0129 | 0.4687 | 0.1071 |
Schistosoma mansoni | coup transcription factor | 0.0244 | 1 | 1 |
Brugia malayi | tailless protein | 0.0115 | 0.4049 | 0.4049 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0244 | 1 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0244 | 1 | 1 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0027 | 0 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0244 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0244 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0115 | 0.4049 | 0.4049 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0244 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0244 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0244 | 1 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0244 | 1 | 1 |
Brugia malayi | nuclear hormone receptor | 0.0115 | 0.4049 | 0.4049 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0244 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0115 | 0.4049 | 0.4049 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0244 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0129 | 0.4687 | 0.4687 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0244 | 1 | 1 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0244 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0244 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0244 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0244 | 1 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0244 | 1 | 1 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0129 | 0.4687 | 0.1071 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0244 | 1 | 1 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0244 | 1 | 1 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0244 | 1 | 1 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0115 | 0.4049 | 0.4049 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0244 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0244 | 1 | 1 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0244 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0244 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0115 | 0.4049 | 0.4049 |
Trypanosoma brucei | cytochrome P450, putative | 0.0027 | 0 | 0.5 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0129 | 0.4687 | 0.4687 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0244 | 1 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0129 | 0.4687 | 0.1071 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0244 | 1 | 1 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0244 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0244 | 1 | 1 |
Brugia malayi | nuclear receptor NHR-88 | 0.0244 | 1 | 1 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0244 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0115 | 0.4049 | 0.4049 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0027 | 0 | 0.5 |
Species name | Source | Reference | Is orphan |
---|---|---|---|
Homo sapiens | ChEMBL23 | 1324320 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.