Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | neuropeptide F receptor | 0.0045 | 0.0452 | 0.0452 |
Onchocerca volvulus | 0.0045 | 0.0452 | 1 | |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0045 | 0.0452 | 0.0444 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0581 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0452 | 0.0452 |
Echinococcus multilocularis | g protein coupled receptor | 0.0045 | 0.0452 | 0.0444 |
Schistosoma mansoni | opsin-like receptor | 0.0045 | 0.0452 | 0.0452 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0045 | 0.0452 | 0.0444 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0045 | 0.0452 | 0.0452 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0045 | 0.0452 | 0.0444 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.1252 | 0.1252 |
Schistosoma mansoni | amine GPCR | 0.0045 | 0.0452 | 0.0452 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0225 | 0.3644 | 0.3644 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0581 | 1 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0045 | 0.0452 | 0.0452 |
Echinococcus granulosus | sex peptide receptor | 0.0045 | 0.0452 | 0.0444 |
Echinococcus multilocularis | serotonin receptor | 0.0045 | 0.0452 | 0.0444 |
Echinococcus granulosus | somatostatin receptor | 0.0045 | 0.0452 | 0.0444 |
Plasmodium falciparum | carbonic anhydrase | 0.0122 | 0.1809 | 0.1803 |
Onchocerca volvulus | 0.0045 | 0.0452 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0154 | 0.0154 |
Brugia malayi | ORL1-like opioid receptor | 0.0045 | 0.0452 | 0.0452 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0452 | 0.0452 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0045 | 0.0452 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0045 | 0.0452 | 0.0452 |
Schistosoma mansoni | isocitrate dehydrogenase | 0.0071 | 0.0899 | 0.0899 |
Brugia malayi | isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial | 0.0071 | 0.0899 | 0.0899 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0581 | 1 | 1 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0045 | 0.0452 | 0.0444 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0045 | 0.0452 | 0.0444 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0021 | 0.0008 | 0.0008 |
Echinococcus granulosus | allatostatin A receptor | 0.0045 | 0.0452 | 0.0444 |
Trypanosoma brucei | carbonic anhydrase-like protein | 0.0225 | 0.3644 | 0.364 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0045 | 0.0452 | 0.0452 |
Schistosoma mansoni | carbonic anhydrase | 0.0122 | 0.1809 | 0.1809 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0045 | 0.0452 | 0.0452 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0021 | 0.0008 | 0.5 |
Brugia malayi | Dopamine receptor | 0.0045 | 0.0452 | 0.0452 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0452 | 0.0452 |
Echinococcus granulosus | carbonic anhydrase | 0.0122 | 0.1809 | 0.1803 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0452 | 0.0452 |
Loa Loa (eye worm) | carbonic anhydrase 3 | 0.0225 | 0.3644 | 0.3644 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0045 | 0.0452 | 0.0444 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0045 | 0.0452 | 0.0452 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0122 | 0.1809 | 0.1809 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0045 | 0.0452 | 0.0444 |
Brugia malayi | Dopamine receptor protein 1 | 0.0045 | 0.0452 | 0.0452 |
Brugia malayi | GnHR receptor homolog | 0.0045 | 0.0452 | 0.0452 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0452 | 0.0452 |
Loa Loa (eye worm) | hypothetical protein | 0.0122 | 0.1809 | 0.1809 |
Mycobacterium leprae | PROBABLE 3-ISOPROPYLMALATE DEHYDROGENASE LEUB (BETA-IPM DEHYDROGENASE) (IMDH) (3-IPM-DH) | 0.0071 | 0.0899 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0452 | 0.0452 |
Brugia malayi | Dopamine receptor protein 2 | 0.0045 | 0.0452 | 0.0452 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0045 | 0.0452 | 0.0452 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0452 | 0.0452 |
Schistosoma mansoni | amine GPCR | 0.0045 | 0.0452 | 0.0452 |
Schistosoma mansoni | hypothetical protein | 0.0045 | 0.0452 | 0.0452 |
Brugia malayi | Isocitrate dehydrogenase | 0.0581 | 1 | 1 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0122 | 0.1809 | 0.1809 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0045 | 0.0452 | 0.0452 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0045 | 0.0452 | 0.0444 |
Echinococcus multilocularis | carbonic anhydrase | 0.0122 | 0.1809 | 0.1803 |
Schistosoma mansoni | neuropeptide receptor | 0.0045 | 0.0452 | 0.0452 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0045 | 0.0452 | 0.0452 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0045 | 0.0452 | 0.0444 |
Echinococcus granulosus | neuropeptide s receptor | 0.0045 | 0.0452 | 0.0444 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0045 | 0.0452 | 0.0452 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0452 | 0.0452 |
Onchocerca volvulus | 0.0045 | 0.0452 | 1 | |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0045 | 0.0452 | 0.0452 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0045 | 0.0452 | 0.0452 |
Echinococcus multilocularis | fmrfamide receptor | 0.0045 | 0.0452 | 0.0444 |
Mycobacterium tuberculosis | Probable 3-isopropylmalate dehydrogenase LeuB (beta-IPM dehydrogenase) (IMDH) (3-IPM-DH) | 0.0071 | 0.0899 | 0.0892 |
Onchocerca volvulus | 0.0045 | 0.0452 | 1 | |
Brugia malayi | AKH receptor | 0.0045 | 0.0452 | 0.0452 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0045 | 0.0452 | 0.0444 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0045 | 0.0452 | 0.0444 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0045 | 0.0452 | 0.0444 |
Echinococcus granulosus | g protein coupled receptor | 0.0045 | 0.0452 | 0.0444 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0899 | 0.0899 |
Echinococcus granulosus | g-protein coupled receptor | 0.0045 | 0.0452 | 0.0444 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0452 | 0.0452 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0452 | 0.0452 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0452 | 0.0452 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0045 | 0.0452 | 0.0444 |
Onchocerca volvulus | 0.0045 | 0.0452 | 1 | |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0045 | 0.0452 | 0.0444 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0045 | 0.0452 | 0.0452 |
Schistosoma mansoni | hypothetical protein | 0.0045 | 0.0452 | 0.0452 |
Brugia malayi | Putative carbonic anhydrase 5 precursor | 0.0225 | 0.3644 | 0.3644 |
Onchocerca volvulus | 0.0045 | 0.0452 | 1 | |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.0225 | 0.3644 | 0.364 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0581 | 1 | 1 |
Onchocerca volvulus | 0.0045 | 0.0452 | 1 | |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0045 | 0.0452 | 0.0444 |
Brugia malayi | isocitrate dehydrogenase [NAD] subunit beta, mitochondrial | 0.0071 | 0.0899 | 0.0899 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0045 | 0.0452 | 0.0444 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0045 | 0.0452 | 0.0452 |
Mycobacterium tuberculosis | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) | 0.0581 | 1 | 1 |
Schistosoma mansoni | amine GPCR | 0.0045 | 0.0452 | 0.0452 |
Echinococcus granulosus | carbonic anhydrase | 0.0122 | 0.1809 | 0.1803 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0045 | 0.0452 | 0.0452 |
Wolbachia endosymbiont of Brugia malayi | isocitrate dehydrogenase | 0.0071 | 0.0899 | 1 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0581 | 1 | 1 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0045 | 0.0452 | 0.0452 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0045 | 0.0452 | 0.0444 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0045 | 0.0452 | 0.0444 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0045 | 0.0452 | 0.0444 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0452 | 0.0452 |
Echinococcus multilocularis | somatostatin receptor | 0.0045 | 0.0452 | 0.0444 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0045 | 0.0452 | 0.0452 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0045 | 0.0452 | 0.0444 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0452 | 0.0452 |
Echinococcus granulosus | neuropeptide receptor | 0.0045 | 0.0452 | 0.0444 |
Echinococcus multilocularis | allatostatin A receptor | 0.0045 | 0.0452 | 0.0444 |
Echinococcus multilocularis | neuropeptide receptor | 0.0045 | 0.0452 | 0.0444 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0581 | 1 | 1 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0045 | 0.0452 | 0.0452 |
Entamoeba histolytica | tartrate dehydrogenase, putative | 0.0071 | 0.0899 | 0.716 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0045 | 0.0452 | 0.0444 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0452 | 0.0452 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0045 | 0.0452 | 0.0452 |
Brugia malayi | hypothetical protein | 0.0045 | 0.0452 | 0.0452 |
Schistosoma mansoni | hypothetical protein | 0.0122 | 0.1809 | 0.1809 |
Echinococcus multilocularis | carbonic anhydrase | 0.0122 | 0.1809 | 0.1803 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0452 | 0.0452 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0045 | 0.0452 | 0.0444 |
Schistosoma mansoni | ap endonuclease | 0.0021 | 0.0008 | 0.0008 |
Onchocerca volvulus | 0.0029 | 0.0154 | 0.3413 | |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0045 | 0.0452 | 0.0452 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0452 | 0.0452 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0452 | 0.0452 |
Echinococcus granulosus | isocitrate dehydrogenase NAD subunit | 0.0071 | 0.0899 | 0.0892 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0452 | 0.0452 |
Echinococcus granulosus | orexin receptor type 2 | 0.0045 | 0.0452 | 0.0444 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0452 | 0.0452 |
Onchocerca volvulus | 0.0045 | 0.0452 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0452 | 0.0452 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0021 | 0.0008 | 0.0008 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.0225 | 0.3644 | 0.364 |
Echinococcus granulosus | neuropeptide receptor | 0.0045 | 0.0452 | 0.0444 |
Brugia malayi | hypothetical protein | 0.0045 | 0.0452 | 0.0452 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0452 | 0.0452 |
Echinococcus multilocularis | serotonin receptor | 0.0045 | 0.0452 | 0.0444 |
Echinococcus granulosus | fmrfamide receptor | 0.0045 | 0.0452 | 0.0444 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0045 | 0.0452 | 0.0444 |
Brugia malayi | Isocitrate dehydrogenase subunit gamma, mitochondrial precursor | 0.0071 | 0.0899 | 0.0899 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0045 | 0.0452 | 0.0444 |
Schistosoma mansoni | Isocitrate dehydrogenase [NAD] subunit gamma mitochondrial | 0.0071 | 0.0899 | 0.0899 |
Schistosoma mansoni | neuropeptide receptor | 0.0045 | 0.0452 | 0.0452 |
Brugia malayi | larval opioid receptor | 0.0045 | 0.0452 | 0.0452 |
Schistosoma mansoni | opsin-like receptor | 0.0045 | 0.0452 | 0.0452 |
Leishmania major | carbonic anhydrase-like protein | 0.0225 | 0.3644 | 0.364 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0045 | 0.0452 | 0.0444 |
Brugia malayi | G protein-coupled receptor | 0.0045 | 0.0452 | 0.0452 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0045 | 0.0452 | 0.0444 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0452 | 0.0452 |
Toxoplasma gondii | hypothetical protein | 0.0122 | 0.1809 | 0.1803 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0045 | 0.0452 | 0.0444 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0045 | 0.0452 | 0.0444 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0045 | 0.0452 | 0.0444 |
Schistosoma mansoni | adenoreceptor | 0.0045 | 0.0452 | 0.0452 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0452 | 0.0452 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0045 | 0.0452 | 0.0444 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0045 | 0.0452 | 0.0444 |
Brugia malayi | G-protein coupled receptor | 0.0045 | 0.0452 | 0.0452 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0045 | 0.0452 | 0.0444 |
Brugia malayi | hypothetical protein | 0.0045 | 0.0452 | 0.0452 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0045 | 0.0452 | 0.0444 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0045 | 0.0452 | 0.0452 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0045 | 0.0452 | 0.0452 |
Brugia malayi | sulfakinin receptor protein | 0.0045 | 0.0452 | 0.0452 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0581 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0045 | 0.0452 | 0.0452 |
Brugia malayi | hypothetical protein | 0.0045 | 0.0452 | 0.0452 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0581 | 1 | 1 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.0225 | 0.3644 | 0.3644 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0045 | 0.0452 | 0.0444 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0452 | 0.0452 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0452 | 0.0452 |
Echinococcus multilocularis | g protein coupled receptor | 0.0045 | 0.0452 | 0.0444 |
Echinococcus multilocularis | carbonic anhydrase II | 0.0225 | 0.3644 | 0.364 |
Echinococcus granulosus | hypothetical protein | 0.0045 | 0.0452 | 0.0444 |
Brugia malayi | putative neuropeptide receptor | 0.0045 | 0.0452 | 0.0452 |
Brugia malayi | Serotonin receptor | 0.0045 | 0.0452 | 0.0452 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0045 | 0.0452 | 0.0444 |
Brugia malayi | hypothetical protein | 0.0029 | 0.0154 | 0.0154 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0045 | 0.0452 | 0.0444 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0045 | 0.0452 | 0.0444 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0045 | 0.0452 | 0.0452 |
Loa Loa (eye worm) | hypothetical protein | 0.0122 | 0.1809 | 0.1809 |
Echinococcus multilocularis | isocitrate dehydrogenase (NAD) subunit | 0.0071 | 0.0899 | 0.0892 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0581 | 1 | 1 |
Brugia malayi | RE15519p | 0.0045 | 0.0452 | 0.0452 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0452 | 0.0452 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0045 | 0.0452 | 0.0452 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0581 | 1 | 1 |
Schistosoma mansoni | biogenic amine receptor | 0.0045 | 0.0452 | 0.0452 |
Mycobacterium ulcerans | 3-isopropylmalate dehydrogenase | 0.0071 | 0.0899 | 1 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0045 | 0.0452 | 0.0452 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0452 | 0.0452 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0045 | 0.0452 | 0.0452 |
Echinococcus granulosus | carbonic anhydrase II | 0.0225 | 0.3644 | 0.364 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0045 | 0.0452 | 0.0444 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0452 | 0.0452 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0581 | 1 | 1 |
Schistosoma mansoni | amine GPCR | 0.0045 | 0.0452 | 0.0452 |
Echinococcus multilocularis | orexin receptor type 2 | 0.0045 | 0.0452 | 0.0444 |
Trichomonas vaginalis | isocitrate dehydrogenase, putative | 0.0071 | 0.0899 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0045 | 0.0452 | 0.0444 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0122 | 0.1809 | 0.1809 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0045 | 0.0452 | 0.0444 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0045 | 0.0452 | 0.0444 |
Echinococcus multilocularis | aryl hydrocarbon receptor | 0.0029 | 0.0154 | 0.0147 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.0225 | 0.3644 | 0.3644 |
Schistosoma mansoni | myosin xvIII | 0.0045 | 0.0452 | 0.0452 |
Onchocerca volvulus | 0.0045 | 0.0452 | 1 | |
Brugia malayi | hypothetical protein | 0.0045 | 0.0452 | 0.0452 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0045 | 0.0452 | 0.0444 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0045 | 0.0452 | 0.0452 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0045 | 0.0452 | 0.0452 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0045 | 0.0452 | 0.0452 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0045 | 0.0452 | 0.0452 |
Onchocerca volvulus | 0.0045 | 0.0452 | 1 | |
Onchocerca volvulus | 0.0045 | 0.0452 | 1 | |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0045 | 0.0452 | 0.0444 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0452 | 0.0452 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0021 | 0.0008 | 0.5 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0581 | 1 | 1 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0045 | 0.0452 | 0.0452 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0045 | 0.0452 | 0.0452 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0045 | 0.0452 | 0.0444 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0045 | 0.0452 | 0.0444 |
Schistosoma mansoni | histamine h1 receptor | 0.0045 | 0.0452 | 0.0452 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0045 | 0.0452 | 0.0444 |
Echinococcus multilocularis | g protein coupled receptor | 0.0045 | 0.0452 | 0.0444 |
Echinococcus granulosus | serotonin receptor | 0.0045 | 0.0452 | 0.0444 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.0122 | 0.1809 | 0.1809 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0045 | 0.0452 | 0.0452 |
Brugia malayi | Probable isocitrate dehydrogenase | 0.0071 | 0.0899 | 0.0899 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0452 | 0.0452 |
Leishmania major | isocitrate dehydrogenase, putative | 0.0071 | 0.0899 | 0.0892 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0045 | 0.0452 | 0.0452 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0045 | 0.0452 | 0.0452 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0045 | 0.0452 | 0.0444 |
Brugia malayi | hypothetical protein | 0.0045 | 0.0452 | 0.0452 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0581 | 1 | 1 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.0122 | 0.1809 | 0.1809 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0452 | 0.0452 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0045 | 0.0452 | 0.0444 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0452 | 0.0452 |
Echinococcus multilocularis | isocitrate dehydrogenase (NAD+) | 0.0071 | 0.0899 | 0.0892 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0045 | 0.0452 | 0.0444 |
Loa Loa (eye worm) | hypothetical protein | 0.0122 | 0.1809 | 0.1809 |
Schistosoma mansoni | amine GPCR | 0.0045 | 0.0452 | 0.0452 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0452 | 0.0452 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0045 | 0.0452 | 0.0452 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0045 | 0.0452 | 0.0444 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0045 | 0.0452 | 0.0452 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0452 | 0.0452 |
Echinococcus multilocularis | sex peptide receptor | 0.0045 | 0.0452 | 0.0444 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0045 | 0.0452 | 0.0452 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0452 | 0.0452 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0452 | 0.0452 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0045 | 0.0452 | 0.0444 |
Brugia malayi | Melatonin receptor type 1A | 0.0045 | 0.0452 | 0.0452 |
Schistosoma mansoni | ap endonuclease | 0.0021 | 0.0008 | 0.0008 |
Brugia malayi | hypothetical protein | 0.0045 | 0.0452 | 0.0452 |
Brugia malayi | hypothetical protein | 0.0045 | 0.0452 | 0.0452 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0045 | 0.0452 | 0.0444 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0045 | 0.0452 | 0.0444 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0045 | 0.0452 | 0.0444 |
Echinococcus granulosus | carbonic anhydrase | 0.0122 | 0.1809 | 0.1803 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.0225 | 0.3644 | 0.3644 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0452 | 0.0452 |
Brugia malayi | follicle stimulating hormone receptor | 0.0045 | 0.0452 | 0.0452 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0452 | 0.0452 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0045 | 0.0452 | 0.0444 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0045 | 0.0452 | 0.0444 |
Onchocerca volvulus | 0.0045 | 0.0452 | 1 | |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0045 | 0.0452 | 0.0452 |
Entamoeba histolytica | Acid sphingomyelinase-like phosphodiesterase, putative | 0.009 | 0.1252 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0452 | 0.0452 |
Brugia malayi | G-protein coupled receptor | 0.0045 | 0.0452 | 0.0452 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0122 | 0.1809 | 0.1809 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0581 | 1 | 1 |
Echinococcus multilocularis | fmrfamide receptor | 0.0045 | 0.0452 | 0.0444 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0045 | 0.0452 | 0.0444 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0045 | 0.0452 | 0.0444 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0045 | 0.0452 | 0.0452 |
Entamoeba histolytica | Acid sphingomyelinase-like phosphodiesterase, putative | 0.009 | 0.1252 | 1 |
Brugia malayi | Probable isocitrate dehydrogenase | 0.0071 | 0.0899 | 0.0899 |
Onchocerca volvulus | 0.0045 | 0.0452 | 1 | |
Echinococcus granulosus | g protein coupled receptor | 0.0045 | 0.0452 | 0.0444 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0045 | 0.0452 | 0.0452 |
Schistosoma mansoni | neuropeptide receptor | 0.0045 | 0.0452 | 0.0452 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0581 | 1 | 1 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0581 | 1 | 1 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0045 | 0.0452 | 0.0452 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0122 | 0.1809 | 0.1809 |
Onchocerca volvulus | 0.0045 | 0.0452 | 1 | |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0581 | 1 | 1 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0045 | 0.0452 | 0.0452 |
Echinococcus granulosus | g protein coupled receptor | 0.0045 | 0.0452 | 0.0444 |
Brugia malayi | neuropeptide F receptor | 0.0045 | 0.0452 | 0.0452 |
Echinococcus granulosus | isocitrate dehydrogenase NAD | 0.0071 | 0.0899 | 0.0892 |
Onchocerca volvulus | 0.0045 | 0.0452 | 1 | |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0045 | 0.0452 | 1 |
Brugia malayi | Serotonin receptor | 0.0045 | 0.0452 | 0.0452 |
Schistosoma mansoni | opsin-like receptor | 0.0045 | 0.0452 | 0.0452 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0452 | 0.0452 |
Onchocerca volvulus | 0.0045 | 0.0452 | 1 | |
Echinococcus multilocularis | neuropeptide receptor | 0.0045 | 0.0452 | 0.0444 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0045 | 0.0452 | 0.0444 |
Brugia malayi | hypothetical protein | 0.0045 | 0.0452 | 0.0452 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0045 | 0.0452 | 0.0444 |
Schistosoma mansoni | unc-13 (munc13) | 0.0071 | 0.0899 | 0.0899 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0045 | 0.0452 | 0.0452 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0045 | 0.0452 | 0.0452 |
Loa Loa (eye worm) | isocitrate dehydrogenase gamma subunit | 0.0071 | 0.0899 | 0.0899 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0452 | 0.0452 |
Loa Loa (eye worm) | aryl Hydrocarbon receptor Associated protein family member | 0.0029 | 0.0154 | 0.0154 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0045 | 0.0452 | 0.0444 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0452 | 0.0452 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0045 | 0.0452 | 0.0452 |
Echinococcus granulosus | aryl hydrocarbon receptor | 0.0029 | 0.0154 | 0.0147 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0045 | 0.0452 | 0.0444 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0452 | 0.0452 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0122 | 0.1809 | 0.1809 |
Schistosoma mansoni | biogenic amine receptor | 0.0045 | 0.0452 | 0.0452 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0452 | 0.0452 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0045 | 0.0452 | 0.0444 |
Schistosoma mansoni | hypothetical protein | 0.0045 | 0.0452 | 0.0452 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0452 | 0.0452 |
Echinococcus multilocularis | carbonic anhydrase | 0.0122 | 0.1809 | 0.1803 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0045 | 0.0452 | 0.0452 |
Onchocerca volvulus | 0.0045 | 0.0452 | 1 | |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0045 | 0.0452 | 0.0444 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.0122 | 0.1809 | 0.1809 |
Schistosoma mansoni | biogenic amine receptor | 0.0045 | 0.0452 | 0.0452 |
Schistosoma mansoni | neuropeptide receptor | 0.0045 | 0.0452 | 0.0452 |
Brugia malayi | hypothetical protein | 0.0045 | 0.0452 | 0.0452 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0045 | 0.0452 | 0.0452 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
ED50 (functional) | > 100 mg kg-1 | In vivo inhibition of conditional avoidance response in rats(CAR), after | ChEMBL. | 1683407 |
IC50 (binding) | nM | Binding affinity against rat 5-hydroxytryptamine 2 receptor in rat cerebral cortex tissue using [3H]-spiperone as radioligand; IA-Inactive | ChEMBL. | 1683407 |
IC50 (binding) | nM | Displacement of [3H]-8-OH-DPAT from rat hippocampal 5-hydroxytryptamine 1A receptor; IA-Inactive | ChEMBL. | 1683407 |
IC50 (binding) | nM | Binding affinity against dopamine receptor D2 in rat corpus striatal tissue using [3H]-spiperone as radioligand;IA-Inactive | ChEMBL. | 1683407 |
IC50 (binding) | nM | Binding affinity against alpha-1 adrenergic receptor in rat cerebral cortex tissue using [3H]-WB-4101 as radioligand;IA-Inactive | ChEMBL. | 1683407 |
IC50 (binding) | 0 nM | Binding affinity against dopamine receptor D2 in rat corpus striatal tissue using [3H]-spiperone as radioligand;IA-Inactive | ChEMBL. | 1683407 |
IC50 (binding) | 0 nM | Displacement of [3H]-8-OH-DPAT from rat hippocampal 5-hydroxytryptamine 1A receptor; IA-Inactive | ChEMBL. | 1683407 |
IC50 (binding) | 0 nM | Binding affinity against rat 5-hydroxytryptamine 2 receptor in rat cerebral cortex tissue using [3H]-spiperone as radioligand; IA-Inactive | ChEMBL. | 1683407 |
IC50 (binding) | 0 nM | Binding affinity against alpha-1 adrenergic receptor in rat cerebral cortex tissue using [3H]-WB-4101 as radioligand;IA-Inactive | ChEMBL. | 1683407 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.