Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0045 | 0.0641 | 0.1071 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0086 | 0.5983 | 0.5983 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0086 | 0.5983 | 1 |
Brugia malayi | nuclear receptor NHR-88 | 0.0086 | 0.5983 | 0.5983 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.5983 | 0.5983 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0086 | 0.5983 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0086 | 0.5983 | 0.5983 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0086 | 0.5983 | 1 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0086 | 0.5983 | 1 |
Brugia malayi | nuclear receptor RXR | 0.0045 | 0.0641 | 0.0641 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0086 | 0.5983 | 0.5983 |
Schistosoma mansoni | thyroid hormone receptor | 0.0086 | 0.5983 | 1 |
Echinococcus granulosus | FTZ F1 alpha | 0.0086 | 0.5983 | 1 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0086 | 0.5983 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0086 | 0.5983 | 0.5983 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0086 | 0.5983 | 1 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0086 | 0.5983 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0086 | 0.5983 | 0.5983 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0086 | 0.5983 | 0.5983 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0045 | 0.0641 | 0.0641 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0086 | 0.5983 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.5983 | 0.5983 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0086 | 0.5983 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0086 | 0.5983 | 0.5983 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0086 | 0.5983 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0086 | 0.5983 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.5983 | 0.5983 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0641 | 0.0641 |
Brugia malayi | ecdysteroid receptor | 0.0086 | 0.5983 | 0.5983 |
Brugia malayi | nuclear hormone receptor | 0.0086 | 0.5983 | 0.5983 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0086 | 0.5983 | 0.5983 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0086 | 0.5983 | 1 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0086 | 0.5983 | 0.5983 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0086 | 0.5983 | 1 |
Brugia malayi | steroid hormone receptor | 0.0086 | 0.5983 | 0.5983 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0116 | 1 | 1 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0086 | 0.5983 | 1 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0086 | 0.5983 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0641 | 0.0641 |
Brugia malayi | hypothetical protein | 0.0045 | 0.0641 | 0.0641 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0086 | 0.5983 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0086 | 0.5983 | 1 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0086 | 0.5983 | 0.5983 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0086 | 0.5983 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0641 | 0.0641 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.5983 | 0.5983 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0086 | 0.5983 | 0.5983 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0086 | 0.5983 | 0.5983 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0086 | 0.5983 | 0.5983 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0086 | 0.5983 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0045 | 0.0641 | 0.0641 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0086 | 0.5983 | 0.5983 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0086 | 0.5983 | 0.5983 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0086 | 0.5983 | 1 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0086 | 0.5983 | 1 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0086 | 0.5983 | 1 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0086 | 0.5983 | 1 |
Schistosoma mansoni | coup transcription factor | 0.0086 | 0.5983 | 1 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0116 | 1 | 1 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0045 | 0.0641 | 0.1071 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0045 | 0.0641 | 0.1071 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0086 | 0.5983 | 0.5983 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0086 | 0.5983 | 0.5983 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0086 | 0.5983 | 0.5983 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.5983 | 0.5983 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0086 | 0.5983 | 1 |
Onchocerca volvulus | 0.0086 | 0.5983 | 1 | |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0086 | 0.5983 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0641 | 0.0641 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0641 | 0.0641 |
Schistosoma mansoni | nuclear hormone receptor | 0.0086 | 0.5983 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0086 | 0.5983 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.5983 | 0.5983 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0086 | 0.5983 | 0.5983 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0086 | 0.5983 | 0.5983 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0086 | 0.5983 | 0.5983 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0086 | 0.5983 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.5983 | 0.5983 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0086 | 0.5983 | 0.5983 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0086 | 0.5983 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0045 | 0.0641 | 0.0641 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0045 | 0.0641 | 0.1071 |
Schistosoma mansoni | thyroid hormone receptor | 0.0086 | 0.5983 | 1 |
Brugia malayi | hypothetical protein | 0.0045 | 0.0641 | 0.0641 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0086 | 0.5983 | 0.5983 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0086 | 0.5983 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.5983 | 0.5983 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0086 | 0.5983 | 0.5983 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.