Detailed information for compound 1867944

Basic information

Technical information
  • TDR Targets ID: 1867944
  • Name: 1-CHLOROTETRADECANE
  • MW: 232.833 | Formula: C14H29Cl
  • H donors: 0 H acceptors: 0 LogP: 7.48 Rotable bonds: 12
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCCCCCCCCCCCCl
  • InChi: 1S/C14H29Cl/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15/h2-14H2,1H3
  • InChiKey: RNHWYOLIEJIAMV-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2425-54-9
  • 252239_ALDRICH
  • Tetradecyl chloride
  • Myristyl chloride
  • EINECS 219-368-0
  • Tetradecane, 1-chloro-

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0049 0.1086 0.1086
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0352 0.1075
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0352 0.1748
Loa Loa (eye worm) hypothetical protein 0.0032 0.0594 0.0594
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0191 0.5142 0.5224
Brugia malayi beta-lactamase family protein 0.0037 0.0728 0.0728
Schistosoma mansoni thyroid hormone receptor 0.0024 0.0373 0.0379
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0024 0.0373 0.0379
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0073 0.1772 0.259
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.0594 0.0603
Onchocerca volvulus Protein ultraspiracle homolog 0.0024 0.0373 0.341
Brugia malayi latrophilin 2 splice variant baaae 0.0247 0.6733 0.6733
Loa Loa (eye worm) hypothetical protein 0.0242 0.6595 0.6595
Loa Loa (eye worm) hypothetical protein 0.0032 0.0594 0.0594
Loa Loa (eye worm) hypothetical protein 0.0032 0.0594 0.0594
Schistosoma mansoni hypothetical protein 0.0355 0.9844 1
Loa Loa (eye worm) hypothetical protein 0.008 0.1971 0.1971
Schistosoma mansoni transcription factor LCR-F1 0.0112 0.2877 0.2922
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0019 0.0227 0.0296
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.0594 0.0603
Loa Loa (eye worm) hypothetical protein 0.0032 0.0594 0.0594
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0032 0.0594 0.0594
Echinococcus granulosus g-protein coupled receptor 0.0032 0.0594 0.0603
Schistosoma mansoni nuclear receptor 0.0012 0.0004 0.0004
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.006 0.1398 1
Loa Loa (eye worm) hypothetical protein 0.0032 0.0594 0.0594
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0024 0.0373 0.0373
Schistosoma mansoni RAR-like nuclear receptor 0.0024 0.0373 0.0379
Loa Loa (eye worm) hypothetical protein 0.0032 0.0594 0.0594
Loa Loa (eye worm) hypothetical protein 0.0361 1 1
Brugia malayi hypothetical protein 0.0032 0.0594 0.0594
Loa Loa (eye worm) steroid hormone receptor 0.0024 0.0373 0.0373
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0017 0.0151 0.207
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0464 0.2789
Echinococcus multilocularis g protein coupled receptor 0.0032 0.0594 0.0603
Brugia malayi nuclear receptor NHR-67 0.0012 0.0004 0.0004
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0037 0.0728 0.092
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.1772 1
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0099 0.2508 0.2547
Schistosoma mansoni aldehyde dehydrogenase 0.0073 0.1772 0.18
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0032 0.0594 0.0603
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.079 0.4746
Brugia malayi nuclear receptor RXR 0.0012 0.0004 0.0004
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0024 0.0373 0.0373
Leishmania major hypothetical protein, conserved 0.0037 0.0728 0.3934
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0032 0.0594 0.0603
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.008 0.1971 0.685
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0032 0.0594 0.0594
Loa Loa (eye worm) hypothetical protein 0.0032 0.0594 0.0594
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.0594 0.0603
Loa Loa (eye worm) hypothetical protein 0.0032 0.0594 0.0594
Echinococcus granulosus orexin receptor type 2 0.0032 0.0594 0.0603
Loa Loa (eye worm) hypothetical protein 0.0032 0.0594 0.0594
Echinococcus granulosus neuropeptide receptor 0.0133 0.3479 0.3534
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0352 0.1075
Echinococcus granulosus FTZ F1 alpha 0.0024 0.0373 0.0379
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0728 0.5028
Loa Loa (eye worm) hypothetical protein 0.0018 0.0196 0.0196
Loa Loa (eye worm) hypothetical protein 0.0032 0.0594 0.0594
Loa Loa (eye worm) latrophilin receptor protein 2 0.0114 0.2941 0.2941
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0024 0.0373 0.0373
Loa Loa (eye worm) hypothetical protein 0.0032 0.0594 0.0594
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.0594 0.0603
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0032 0.0594 0.0603
Brugia malayi beta-lactamase 0.0037 0.0728 0.0728
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0032 0.0594 0.0594
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0032 0.0594 0.0594
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0037 0.0728 0.0728
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0361 1 1
Echinococcus multilocularis neuropeptides capa receptor 0.0032 0.0594 0.0603
Brugia malayi GnHR receptor homolog 0.0032 0.0594 0.0594
Onchocerca volvulus 0.0032 0.0594 0.5455
Loa Loa (eye worm) hypothetical protein 0.0013 0.0043 0.0043
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0032 0.0594 0.0603
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Schistosoma mansoni myosin xvIII 0.0032 0.0594 0.0603
Onchocerca volvulus Neuropeptide F receptor homolog 0.0032 0.0594 0.5455
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0039 0.079 0.7266
Loa Loa (eye worm) beta-lactamase 0.0037 0.0728 0.0728
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0024 0.0373 0.0373
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0024 0.0373 0.0379
Loa Loa (eye worm) hypothetical protein 0.0124 0.3221 0.3221
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0032 0.0594 0.0603
Onchocerca volvulus 0.0032 0.0594 0.5455
Brugia malayi Melatonin receptor type 1A 0.0032 0.0594 0.0594
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0032 0.0594 0.0603
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0024 0.0373 0.0379
Echinococcus multilocularis survival motor neuron protein 1 0.0242 0.6595 0.6699
Schistosoma mansoni survival motor neuron protein 0.0049 0.1086 0.1103
Brugia malayi steroid hormone receptor 0.0024 0.0373 0.0373
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0037 0.0728 0.344
Echinococcus multilocularis serotonin receptor 0.0032 0.0594 0.0603
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0032 0.0594 0.0603
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0024 0.0373 0.0373
Echinococcus granulosus chromobox protein 1 0.007 0.1665 0.1691
Echinococcus granulosus neuropeptide s receptor 0.0032 0.0594 0.0603
Loa Loa (eye worm) hypothetical protein 0.0032 0.0594 0.0594
Schistosoma mansoni hypothetical protein 0.0355 0.9844 1
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0024 0.0373 0.0379
Echinococcus multilocularis sex peptide receptor 0.0032 0.0594 0.0603
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0728 0.4373
Entamoeba histolytica hypothetical protein 0.0112 0.2877 1
Loa Loa (eye worm) neuropeptide F receptor 0.0032 0.0594 0.0594
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0032 0.0594 0.0594
Schistosoma mansoni aldehyde dehydrogenase 0.0073 0.1772 0.18
Schistosoma mansoni neuropeptide receptor 0.0032 0.0594 0.0603
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0728 0.4373
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0013 0.0043 0.0044
Loa Loa (eye worm) nuclear receptor NHR-67 0.0012 0.0004 0.0004
Brugia malayi neuropeptide F receptor 0.0032 0.0594 0.0594
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0032 0.0594 0.0603
Loa Loa (eye worm) hypothetical protein 0.0032 0.0594 0.0594
Loa Loa (eye worm) hypothetical protein 0.0018 0.018 0.018
Trypanosoma cruzi cytochrome P450, putative 0.0019 0.0227 0.1312
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.1772 1
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0032 0.0594 0.0603
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0191 0.5142 0.5224
Schistosoma mansoni nuclear receptor 0.0012 0.0004 0.0004
Echinococcus multilocularis G-protein coupled receptor, putative 0.0032 0.0594 0.0603
Entamoeba histolytica hypothetical protein 0.0112 0.2877 1
Mycobacterium tuberculosis Probable lipase LipD 0.0037 0.0728 0.092
Loa Loa (eye worm) hypothetical protein 0.0032 0.0594 0.0594
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0024 0.0373 0.0379
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0032 0.0594 0.0603
Brugia malayi Dopamine receptor 0.0032 0.0594 0.0594
Echinococcus granulosus serotonin receptor 0.0032 0.0594 0.0603
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Onchocerca volvulus 0.0037 0.0728 0.6693
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Echinococcus granulosus g protein coupled receptor 0.0032 0.0594 0.0603
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0032 0.0594 0.0594
Loa Loa (eye worm) hypothetical protein 0.0024 0.0373 0.0373
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0012 0.0004 0.0004
Loa Loa (eye worm) G-protein coupled receptor 0.0032 0.0594 0.0594
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0024 0.0373 0.0373
Echinococcus granulosus chromobox protein 1 0.007 0.1665 0.1691
Loa Loa (eye worm) hypothetical protein 0.0032 0.0594 0.0594
Loa Loa (eye worm) hypothetical protein 0.0032 0.0594 0.0594
Loa Loa (eye worm) cytochrome P450 family protein 0.0049 0.1067 0.1067
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0099 0.2508 0.2547
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0114 0.2941 0.2988
Echinococcus granulosus tm gpcr rhodopsin 0.0032 0.0594 0.0603
Echinococcus granulosus bloom syndrome protein 0.0025 0.0379 0.0385
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0464 0.2789
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.0594 0.0603
Brugia malayi hypothetical protein 0.0032 0.0594 0.0594
Schistosoma mansoni chromobox protein 0.007 0.1665 0.1691
Echinococcus multilocularis neuropeptide FF receptor 2 0.0032 0.0594 0.0603
Brugia malayi orphan nuclear receptor NR2E1 0.0012 0.0004 0.0004
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0012 0.0004 0.0004
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.006 0.1398 1
Schistosoma mansoni biogenic amine receptor 0.0032 0.0594 0.0603
Loa Loa (eye worm) hypothetical protein 0.0024 0.0373 0.0373
Echinococcus multilocularis neuropeptide Y receptor 0.0032 0.0594 0.0603
Brugia malayi ORL1-like opioid receptor 0.0032 0.0594 0.0594
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0024 0.0373 0.0379
Mycobacterium ulcerans beta-lactamase 0.0037 0.0728 0.344
Trichomonas vaginalis chromobox protein, putative 0.007 0.1665 1
Echinococcus granulosus hypothetical protein 0.0032 0.0594 0.0603
Echinococcus granulosus allatostatin A receptor 0.0032 0.0594 0.0603
Loa Loa (eye worm) hypothetical protein 0.0018 0.0196 0.0196
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0073 0.1772 0.18
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0032 0.0594 0.0603
Echinococcus multilocularis voltage dependent calcium channel 0.0099 0.2508 0.2547
Schistosoma mansoni opsin-like receptor 0.0032 0.0594 0.0603
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0024 0.0373 0.0379
Loa Loa (eye worm) hypothetical protein 0.0032 0.0594 0.0594
Trichomonas vaginalis DNA helicase recq, putative 0.0013 0.0051 0.0304
Loa Loa (eye worm) hypothetical protein 0.0032 0.0594 0.0594
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.0594 0.0603
Loa Loa (eye worm) hypothetical protein 0.0013 0.0043 0.0043
Trypanosoma brucei cytochrome P450, putative 0.0019 0.0227 0.1312
Brugia malayi neuropeptide F receptor 0.0032 0.0594 0.0594
Echinococcus multilocularis neuropeptide receptor A26 0.0032 0.0594 0.0603
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0032 0.0594 0.0603
Schistosoma mansoni amine GPCR 0.0032 0.0594 0.0603
Brugia malayi G-protein coupled receptor 0.0032 0.0594 0.0594
Loa Loa (eye worm) hypothetical protein 0.0032 0.0594 0.0594
Brugia malayi Heterochromatin protein 1 0.007 0.1665 0.1665
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Schistosoma mansoni hypothetical protein 0.0032 0.0594 0.0603
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0114 0.2941 0.2988
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.0594 0.0603
Echinococcus granulosus survival motor neuron protein 1 0.0242 0.6595 0.6699
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0352 0.1222
Loa Loa (eye worm) RecQ helicase 0.0025 0.0379 0.0379
Brugia malayi nuclear hormone receptor family member nhr-6 0.0012 0.0004 0.0004
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0875 0.5254
Onchocerca volvulus 0.0032 0.0594 0.5455
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0728 0.4373
Echinococcus multilocularis voltage dependent calcium channel 0.0099 0.2508 0.2547
Loa Loa (eye worm) hypothetical protein 0.0247 0.6733 0.6733
Loa Loa (eye worm) hypothetical protein 0.0018 0.018 0.018
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0191 0.5142 0.5224
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.0594 0.0603
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.0594 0.0603
Brugia malayi nuclear receptor NHR-88 0.0024 0.0373 0.0373
Onchocerca volvulus 0.0024 0.0373 0.341
Brugia malayi beta-lactamase family protein 0.0037 0.0728 0.0728
Loa Loa (eye worm) hypothetical protein 0.0024 0.0352 0.0352
Loa Loa (eye worm) hypothetical protein 0.0032 0.0594 0.0594
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0037 0.0728 0.0728
Mycobacterium ulcerans esterase/lipase LipP 0.0037 0.0728 0.344
Echinococcus granulosus somatostatin receptor 0.0032 0.0594 0.0603
Onchocerca volvulus 0.0032 0.0594 0.5455
Brugia malayi nuclear hormone receptor 0.0024 0.0373 0.0373
Schistosoma mansoni nuclear hormone receptor 0.0012 0.0004 0.0004
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0032 0.0594 0.0603
Loa Loa (eye worm) calcium channel 0.0099 0.2508 0.2508
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0018 0.018 0.5
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.0594 0.0603
Schistosoma mansoni chromobox protein 0.007 0.1665 0.1691
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.008 0.1971 0.685
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0022 0.0293 1
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0024 0.0373 0.0379
Brugia malayi Serotonin receptor 0.0032 0.0594 0.0594
Schistosoma mansoni hypothetical protein 0.0032 0.0594 0.0603
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0024 0.0373 0.0373
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0013 0.0043 0.0044
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0728 0.0739
Brugia malayi G protein-coupled receptor 0.0032 0.0594 0.0594
Echinococcus granulosus biogenic amine 5HT receptor 0.0032 0.0594 0.0603
Brugia malayi sulfakinin receptor protein 0.0032 0.0594 0.0594
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0024 0.0373 0.0373
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.0594 0.0603
Brugia malayi Serotonin receptor 0.0032 0.0594 0.0594
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0114 0.2941 0.2941
Echinococcus granulosus thyroid hormone receptor alpha 0.0012 0.0004 0.0004
Onchocerca volvulus 0.0032 0.0594 0.5455
Loa Loa (eye worm) hypothetical protein 0.0032 0.0594 0.0594
Loa Loa (eye worm) hypothetical protein 0.0114 0.2941 0.2941
Brugia malayi RE15519p 0.0032 0.0594 0.0594
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0024 0.0373 0.0379
Loa Loa (eye worm) nuclear hormone receptor 0.0012 0.0004 0.0004
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0024 0.0373 0.0373
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0099 0.2508 0.2547
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0032 0.0594 0.0603
Entamoeba histolytica hypothetical protein 0.0112 0.2877 1
Echinococcus multilocularis nuclear receptor nhr 48 0.0012 0.0004 0.0004
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0235 0.6406 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.0594 0.0603
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0073 0.1772 1
Schistosoma mansoni neuropeptide F-like receptor 0.0032 0.0594 0.0603
Loa Loa (eye worm) cytochrome P450 family protein 0.0019 0.0227 0.0227
Brugia malayi Nuclear hormone receptor-like 1 0.0024 0.0373 0.0373
Brugia malayi hypothetical protein 0.0032 0.0594 0.0594
Schistosoma mansoni zinc finger protein 0.0012 0.0004 0.0004
Trypanosoma cruzi cytochrome P450, putative 0.0019 0.0227 0.1312
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0032 0.0594 0.0603
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0352 0.1075
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0352 0.0352
Brugia malayi Calcitonin receptor-like protein seb-1 0.0361 1 1
Schistosoma mansoni thyroid hormone receptor 0.0024 0.0373 0.0379
Echinococcus multilocularis chromobox protein 1 0.007 0.1665 0.1691
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.0594 0.0603
Loa Loa (eye worm) hypothetical protein 0.0037 0.0728 0.0728
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0191 0.5142 0.5142
Leishmania major cytochrome p450-like protein 0.0019 0.0227 0.1026
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0032 0.0594 0.0603
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0099 0.2508 0.2547
Onchocerca volvulus 0.0031 0.0549 0.5039
Loa Loa (eye worm) hypothetical protein 0.0032 0.0594 0.0594
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0013 0.0043 0.0044
Brugia malayi Tachykinin-like peptides receptor 99D 0.0032 0.0594 0.0594
Toxoplasma gondii transporter, cation channel family protein 0.0021 0.0267 0.1509
Loa Loa (eye worm) hypothetical protein 0.0013 0.0043 0.0043
Schistosoma mansoni opsin-like receptor 0.0032 0.0594 0.0603
Onchocerca volvulus 0.0032 0.0594 0.5455
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0032 0.0594 0.0603
Echinococcus granulosus neuropeptides capa receptor 0.0032 0.0594 0.0603
Schistosoma mansoni blooms syndrome DNA helicase 0.0019 0.0231 0.0234
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0032 0.0594 0.0603
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0032 0.0594 0.0603
Onchocerca volvulus Bile acid receptor homolog 0.0024 0.0373 0.341
Brugia malayi photoreceptor-specific nuclear receptor 0.0024 0.0373 0.0373
Echinococcus multilocularis g protein coupled receptor 0.0032 0.0594 0.0603
Loa Loa (eye worm) hypothetical protein 0.0032 0.0594 0.0594
Loa Loa (eye worm) hypothetical protein 0.0032 0.0594 0.0594
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0013 0.0043 0.0043
Echinococcus granulosus tm gpcr rhodopsin 0.0032 0.0594 0.0603
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0099 0.2508 0.2547
Echinococcus granulosus dro:myosuppressin receptor 0.0032 0.0594 0.0603
Echinococcus granulosus 7TM GPCR rhodopsin 0.0032 0.0594 0.0603
Schistosoma mansoni hypothetical protein 0.0247 0.6733 0.6839
Loa Loa (eye worm) hypothetical protein 0.0018 0.018 0.018
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0024 0.0373 0.0379
Mycobacterium tuberculosis Conserved protein 0.0037 0.0728 0.092
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0024 0.0373 0.0373
Schistosoma mansoni nuclear hormone receptor 0.0024 0.0373 0.0379
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0073 0.1772 0.18
Echinococcus multilocularis fmrfamide receptor 0.0032 0.0594 0.0603
Schistosoma mansoni hypothetical protein 0.0112 0.2877 0.2922
Loa Loa (eye worm) hypothetical protein 0.0032 0.0594 0.0594
Brugia malayi nuclear receptor NHR-88 0.0012 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0037 0.0728 0.0728
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0042 0.0876 0.089
Brugia malayi Nuclear hormone receptor-like 1 0.0013 0.0043 0.0043
Echinococcus multilocularis g protein coupled receptor 0.0032 0.0594 0.0603
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0012 0.0004 0.0004
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0032 0.0594 0.0603
Mycobacterium ulcerans lipase LipD 0.0037 0.0728 0.344
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0352 0.1075
Echinococcus multilocularis neuropeptides capa receptor 0.0032 0.0594 0.0603
Trichomonas vaginalis chromobox protein, putative 0.007 0.1665 1
Loa Loa (eye worm) hypothetical protein 0.0039 0.079 0.079
Echinococcus multilocularis chromobox protein 1 0.007 0.1665 0.1691
Schistosoma mansoni amine GPCR 0.0032 0.0594 0.0603
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0024 0.0373 0.0373
Brugia malayi nuclear hormone receptor family member odr-7 0.0012 0.0004 0.0004
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0352 0.0352
Loa Loa (eye worm) hypothetical protein 0.0032 0.0594 0.0594
Loa Loa (eye worm) hypothetical protein 0.0032 0.0594 0.0594
Onchocerca volvulus 0.0037 0.0728 0.6693
Loa Loa (eye worm) hypothetical protein 0.0024 0.0373 0.0373
Onchocerca volvulus 0.0032 0.0594 0.5455
Brugia malayi hypothetical protein 0.0032 0.0594 0.0594
Echinococcus granulosus g protein coupled receptor 0.0032 0.0594 0.0603
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0012 0.0004 0.0004
Brugia malayi tailless protein 0.0012 0.0004 0.0004
Echinococcus multilocularis G protein coupled receptor 139 0.0133 0.3479 0.3534
Schistosoma mansoni histamine h1 receptor 0.0032 0.0594 0.0603
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Schistosoma mansoni hypothetical protein 0.0032 0.0594 0.0603
Echinococcus granulosus sex peptide receptor 0.0032 0.0594 0.0603
Echinococcus multilocularis beta LACTamase domain containing family member 0.0037 0.0728 0.0739
Onchocerca volvulus 0.0032 0.0594 0.5455
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.0594 0.0603
Echinococcus granulosus G protein coupled receptor 139 0.0032 0.0594 0.0603
Loa Loa (eye worm) hypothetical protein 0.0032 0.0594 0.0594
Loa Loa (eye worm) hypothetical protein 0.0032 0.0594 0.0594
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0024 0.0373 0.0373
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0352 0.1748
Echinococcus granulosus tachykinin peptides receptor 99D 0.0032 0.0594 0.0603
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0032 0.0594 0.0603
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0099 0.2508 0.2547
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0728 0.0739
Schistosoma mansoni hypothetical protein 0.0114 0.2941 0.2988
Loa Loa (eye worm) hypothetical protein 0.0037 0.0728 0.0728
Echinococcus multilocularis GPCR, family 2 0.0114 0.2941 0.2988
Echinococcus multilocularis neuropeptide receptor 0.0032 0.0594 0.0603
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.079 0.4746
Brugia malayi hypothetical protein 0.0032 0.0594 0.0594
Toxoplasma gondii aldehyde dehydrogenase 0.0073 0.1772 1
Brugia malayi Dopamine receptor protein 2 0.0032 0.0594 0.0594
Echinococcus multilocularis somatostatin receptor 0.0032 0.0594 0.0603
Echinococcus multilocularis neuropeptide Y receptor 0.0032 0.0594 0.0603
Brugia malayi hypothetical protein 0.0032 0.0594 0.0594
Echinococcus multilocularis neuropeptide receptor 0.0133 0.3479 0.3534
Schistosoma mansoni neuropeptide receptor 0.0032 0.0594 0.0603
Loa Loa (eye worm) hypothetical protein 0.0037 0.0728 0.0728
Brugia malayi hypothetical protein 0.0012 0.0004 0.0004
Trypanosoma brucei hypothetical protein, conserved 0.0037 0.0728 0.5028
Loa Loa (eye worm) hypothetical protein 0.0032 0.0594 0.0594
Brugia malayi ecdysteroid receptor 0.0024 0.0373 0.0373
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0024 0.0373 0.341
Schistosoma mansoni biogenic amine (5HT) receptor 0.0032 0.0594 0.0603
Schistosoma mansoni steroid hormone receptor ad4bp 0.0024 0.0373 0.0379
Echinococcus granulosus tm gpcr rhodopsin 0.0032 0.0594 0.0603
Loa Loa (eye worm) cytochrome P450 family protein 0.0019 0.0227 0.0227
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0024 0.0373 0.0373
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0099 0.2508 0.2547
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.0594 0.0603
Loa Loa (eye worm) hypothetical protein 0.0024 0.0373 0.0373
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0032 0.0594 0.0603
Echinococcus multilocularis FTZ F1 alpha 0.0024 0.0373 0.0379
Loa Loa (eye worm) hypothetical protein 0.0032 0.0594 0.0594
Brugia malayi chromobox protein homolog 3 0.0039 0.079 0.079
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0037 0.0728 0.092
Echinococcus multilocularis ecdysone induced protein 78C 0.0024 0.0373 0.0379
Echinococcus granulosus ecdysone induced protein 78C 0.0024 0.0373 0.0379
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0352 0.0318
Loa Loa (eye worm) hypothetical protein 0.0013 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0032 0.0594 0.0594
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0032 0.0594 0.0594
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0191 0.5142 0.5224
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0024 0.0373 0.0379
Plasmodium vivax acyl-CoA synthetase, putative 0.0018 0.018 0.2477
Loa Loa (eye worm) hypothetical protein 0.0037 0.0728 0.0728
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0013 0.0043 0.0044
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0024 0.0373 0.0373
Echinococcus granulosus g protein coupled receptor 0.0032 0.0594 0.0603
Onchocerca volvulus 0.0024 0.0352 0.3215
Brugia malayi Nuclear hormone receptor E75 0.0012 0.0004 0.0004
Echinococcus granulosus 7tm_1 domain containing protein 0.0032 0.0594 0.0603
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0191 0.5142 0.5224
Loa Loa (eye worm) hypothetical protein 0.0032 0.0594 0.0594
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.0594 0.0603
Onchocerca volvulus 0.0032 0.0594 0.5455
Trichomonas vaginalis esterase, putative 0.0037 0.0728 0.4373
Onchocerca volvulus 0.0032 0.0594 0.5455
Echinococcus granulosus peptide allatostatin:somatostatin 0.0032 0.0594 0.0603
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Loa Loa (eye worm) melatonin receptor type 1A 0.0032 0.0594 0.0594
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0012 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0032 0.0594 0.0603
Schistosoma mansoni amine GPCR 0.0032 0.0594 0.0603
Loa Loa (eye worm) hypothetical protein 0.0024 0.0373 0.0373
Loa Loa (eye worm) hypothetical protein 0.0018 0.018 0.018
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.0352 0.0318
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0352 0.1222
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0352 0.1222
Brugia malayi nuclear receptor RXR 0.0013 0.0043 0.0043
Echinococcus granulosus voltage dependent calcium channel 0.0099 0.2508 0.2547
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0024 0.0373 0.0379
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0191 0.5142 0.5224
Echinococcus granulosus fmrfamide receptor 0.0032 0.0594 0.0603
Brugia malayi Cytochrome P450 family protein 0.0019 0.0227 0.0227
Schistosoma mansoni biogenic amine receptor 0.0032 0.0594 0.0603
Loa Loa (eye worm) hypothetical protein 0.0032 0.0594 0.0594
Brugia malayi hypothetical protein 0.0032 0.0594 0.0594
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0024 0.0373 0.0379
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0099 0.2508 0.2508
Trichomonas vaginalis DNA helicase recq1, putative 0.0025 0.0379 0.2276
Loa Loa (eye worm) follicle stimulating hormone receptor 0.031 0.8543 0.8543
Loa Loa (eye worm) hypothetical protein 0.0032 0.0594 0.0594
Loa Loa (eye worm) voltage-dependent calcium channel 0.0021 0.0267 0.0267
Loa Loa (eye worm) hypothetical protein 0.0021 0.0267 0.0267
Schistosoma mansoni biogenic amine receptor 0.0032 0.0594 0.0603
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0032 0.0594 0.0603
Brugia malayi hypothetical protein 0.0112 0.2877 0.2877
Schistosoma mansoni alpha-1 adrenergic receptor 0.0032 0.0594 0.0603
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0032 0.0594 0.0603
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Schistosoma mansoni neuropeptide receptor 0.0133 0.3479 0.3534
Brugia malayi hypothetical protein 0.0032 0.0594 0.0594
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0032 0.0594 0.0594
Entamoeba histolytica hypothetical protein 0.0112 0.2877 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0024 0.0373 0.0379
Echinococcus granulosus voltage dependent calcium channel 0.0021 0.0267 0.0272
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0024 0.0373 0.0379
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0012 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Echinococcus granulosus geminin 0.0355 0.9844 1
Echinococcus granulosus neuropeptide FF receptor 2 0.0032 0.0594 0.0603
Brugia malayi Cytochrome P450 family protein 0.0019 0.0227 0.0227
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0114 0.2941 0.2988
Mycobacterium tuberculosis Probable hydrolase 0.0037 0.0728 0.092
Loa Loa (eye worm) hypothetical protein 0.0032 0.0594 0.0594
Brugia malayi G-protein coupled receptor 0.0032 0.0594 0.0594
Echinococcus granulosus GPCR family 2 0.0114 0.2941 0.2988
Trichomonas vaginalis DNA helicase recq, putative 0.0025 0.0379 0.2276
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0024 0.0373 0.0373
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.0875 0.8049
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0032 0.0594 0.0603
Loa Loa (eye worm) hypothetical protein 0.0032 0.0594 0.0594
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0352 0.1075
Loa Loa (eye worm) hypothetical protein 0.0024 0.0352 0.0352
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0032 0.0594 0.0594
Echinococcus granulosus beta LACTamase domain containing family member 0.0037 0.0728 0.0739
Schistosoma mansoni coup transcription factor 0.0024 0.0373 0.0379
Echinococcus granulosus neuropeptide Y receptor 0.0032 0.0594 0.0603
Schistosoma mansoni retinoic acid receptor RXR 0.0024 0.0373 0.0379
Loa Loa (eye worm) hypothetical protein 0.0032 0.0594 0.0594
Loa Loa (eye worm) hypothetical protein 0.0032 0.0594 0.0594
Echinococcus granulosus neuropeptides capa receptor 0.0032 0.0594 0.0603
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0024 0.0373 0.0373
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0024 0.0373 0.0373
Brugia malayi putative neuropeptide receptor NPR1 0.0032 0.0594 0.0594
Loa Loa (eye worm) hypothetical protein 0.0032 0.0594 0.0594
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0024 0.0373 0.0373
Loa Loa (eye worm) hypothetical protein 0.0032 0.0594 0.0594
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.0594 0.0603
Echinococcus granulosus alpha 1A adrenergic receptor 0.0032 0.0594 0.0603
Brugia malayi ecdysone receptor 0.0012 0.0004 0.0004
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0114 0.2941 0.2988
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0352 0.1075
Echinococcus granulosus neuropeptide Y receptor 0.0032 0.0594 0.0603
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0191 0.5142 0.5224
Echinococcus multilocularis sodium channel protein 0.0042 0.0876 0.089
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0016 0.0145 0.0818
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.0594 0.0603
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0728 0.4373
Schistosoma mansoni amine GPCR 0.0032 0.0594 0.0603
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0112 0.2877 0.2922
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.018 0.0044
Brugia malayi Nuclear hormone receptor-like 1 0.0013 0.0043 0.0043
Echinococcus multilocularis neuropeptide s receptor 0.0032 0.0594 0.0603
Brugia malayi Nuclear hormone receptor E75 0.0012 0.0004 0.0004
Toxoplasma gondii hypothetical protein 0.0018 0.0196 0.1105
Echinococcus multilocularis serotonin receptor 0.0032 0.0594 0.0603
Echinococcus granulosus Nuclear hormone receptor HR96 0.0012 0.0004 0.0004
Echinococcus multilocularis dro:myosuppressin receptor 0.0032 0.0594 0.0603
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0012 0.0004 0.0004
Brugia malayi hypothetical protein 0.0013 0.0043 0.0043
Schistosoma mansoni neuropeptide F-like receptor 0.0032 0.0594 0.0603
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0099 0.2508 0.2547
Schistosoma mansoni amine GPCR 0.0032 0.0594 0.0603
Echinococcus granulosus neuropeptide receptor A26 0.0032 0.0594 0.0603
Schistosoma mansoni hypothetical protein 0.0114 0.2941 0.2988
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0012 0.0004 0.0004
Mycobacterium leprae conserved hypothetical protein 0.0037 0.0728 1
Echinococcus multilocularis geminin 0.0355 0.9844 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.0352 0.0352
Entamoeba histolytica recQ family helicase, putative 0.0013 0.0051 0.0176
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0032 0.0594 0.0603
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0032 0.0594 0.0603
Schistosoma mansoni growth hormone secretagogue receptor 0.0032 0.0594 0.0603
Loa Loa (eye worm) neuropeptide F receptor 0.0032 0.0594 0.0594
Loa Loa (eye worm) hypothetical protein 0.0099 0.2508 0.2508
Echinococcus granulosus Nuclear hormone receptor HR96 0.0012 0.0004 0.0004
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0024 0.0373 0.0373
Mycobacterium tuberculosis Conserved protein 0.0037 0.0728 0.092
Brugia malayi hypothetical protein 0.0032 0.0594 0.0594
Schistosoma mansoni nuclear hormone receptor 0.0012 0.0004 0.0004
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0032 0.0594 0.0603
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0032 0.0594 0.5455
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0032 0.0594 0.0603
Loa Loa (eye worm) hypothetical protein 0.0037 0.0728 0.0728
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0024 0.0373 0.0379
Mycobacterium tuberculosis Probable lipase LipE 0.0037 0.0728 0.092
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0012 0.0004 0.0004
Schistosoma mansoni neuropeptide f receptor 76f 0.0032 0.0594 0.0603
Onchocerca volvulus 0.0032 0.0594 0.5455
Onchocerca volvulus 0.0049 0.1086 1
Echinococcus multilocularis allatostatin A receptor 0.0032 0.0594 0.0603
Schistosoma mansoni neuropeptide receptor 0.0032 0.0594 0.0603
Onchocerca volvulus 0.0032 0.0594 0.5455
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0112 0.2877 0.2922
Brugia malayi hypothetical protein 0.0012 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0031 0.0549 0.0549
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0728 0.5028
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0037 0.0728 0.092
Onchocerca volvulus 0.0032 0.0594 0.5455
Brugia malayi G protein-coupled receptor F59B2.13 0.0032 0.0594 0.0594
Mycobacterium leprae Probable lipase LipE 0.0037 0.0728 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Loa Loa (eye worm) DR-78 0.0012 0.0004 0.0004
Echinococcus granulosus nuclear receptor nhr 48 0.0012 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0032 0.0594 0.0594
Plasmodium falciparum acyl-CoA synthetase 0.0018 0.018 0.6148
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.0594 0.0603
Echinococcus multilocularis g-protein coupled receptor 0.0032 0.0594 0.0603
Loa Loa (eye worm) hypothetical protein 0.0024 0.0373 0.0373
Mycobacterium tuberculosis Conserved protein 0.0037 0.0728 0.092
Brugia malayi hypothetical protein 0.0013 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0032 0.0594 0.0594
Onchocerca volvulus 0.0032 0.0594 0.5455
Brugia malayi hypothetical protein 0.0032 0.0594 0.0594
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0024 0.0373 0.0379
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0032 0.0594 0.0603
Echinococcus multilocularis orexin receptor type 2 0.0032 0.0594 0.0603
Schistosoma mansoni voltage-gated cation channel 0.0099 0.2508 0.2547
Schistosoma mansoni nuclear receptor nhr-48 0.0012 0.0004 0.0004
Brugia malayi putative neuropeptide receptor 0.0032 0.0594 0.0594
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0012 0.0004 0.0004
Brugia malayi conserved hypotetical protein 0.0012 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0024 0.0373 0.0373
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0352 0.1748
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0875 0.5254
Onchocerca volvulus 0.0037 0.0728 0.6693
Brugia malayi Bloom's syndrome protein homolog 0.0025 0.0379 0.0379
Brugia malayi hypothetical protein 0.0242 0.6595 0.6595
Brugia malayi Latrophilin receptor protein 2 0.0114 0.2941 0.2941
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0352 0.0352
Brugia malayi larval opioid receptor 0.0032 0.0594 0.0594
Schistosoma mansoni adenoreceptor 0.0032 0.0594 0.0603
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0012 0.0004 0.0004
Echinococcus granulosus biogenic amine 5HT receptor 0.0032 0.0594 0.0603
Brugia malayi AKH receptor 0.0032 0.0594 0.0594
Onchocerca volvulus 0.0032 0.0594 0.5455
Loa Loa (eye worm) hypothetical protein 0.0024 0.0373 0.0373
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0191 0.5142 0.5142
Brugia malayi Dopamine receptor protein 1 0.0032 0.0594 0.0594
Echinococcus multilocularis fmrfamide receptor 0.0032 0.0594 0.0603
Plasmodium vivax hypothetical protein, conserved 0.0037 0.0728 1
Loa Loa (eye worm) hypothetical protein 0.0032 0.0594 0.0594
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.0594 0.0603
Schistosoma mansoni hypothetical protein 0.0032 0.0594 0.0603
Loa Loa (eye worm) hypothetical protein 0.0018 0.018 0.018
Brugia malayi follicle stimulating hormone receptor 0.031 0.8543 0.8543
Loa Loa (eye worm) heterochromatin protein 1 0.007 0.1665 0.1665
Schistosoma mansoni biogenic amine (5HT) receptor 0.0032 0.0594 0.0603
Toxoplasma gondii ABC1 family protein 0.0037 0.0728 0.4107
Mycobacterium ulcerans hypothetical protein 0.0037 0.0728 0.344
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0024 0.0373 0.0379
Echinococcus multilocularis thyroid hormone receptor alpha 0.0024 0.0373 0.0379
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.0594 0.0603
Echinococcus multilocularis bloom syndrome protein 0.0025 0.0379 0.0385
Loa Loa (eye worm) hypothetical protein 0.0032 0.0594 0.0594
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.0594 0.0603
Mycobacterium tuberculosis Probable esterase LipL 0.0037 0.0728 0.092
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.1772 1
Brugia malayi Cytochrome P450 family protein 0.0049 0.1067 0.1067
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.0594 0.0603
Onchocerca volvulus 0.0032 0.0594 0.5455
Schistosoma mansoni hypothetical protein 0.0114 0.2941 0.2988
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0032 0.0594 0.0603
Onchocerca volvulus 0.0032 0.0594 0.5455
Loa Loa (eye worm) G-protein coupled receptor 0.0032 0.0594 0.0594
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0032 0.0594 0.0603
Schistosoma mansoni hypothetical protein 0.0114 0.2941 0.2988
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0352 0.1075
Loa Loa (eye worm) CYP4Cod1 0.0019 0.0227 0.0227
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0024 0.0373 0.0379
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0024 0.0373 0.0373
Mycobacterium ulcerans hypothetical protein 0.0024 0.0352 0.1075
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0099 0.2508 0.2547
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.0594 0.0603
Loa Loa (eye worm) hypothetical protein 0.0013 0.0043 0.0043
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0728 0.4373
Schistosoma mansoni hypothetical protein 0.0049 0.1086 0.1103
Schistosoma mansoni opsin-like receptor 0.0032 0.0594 0.0603
Brugia malayi Steroid receptor seven-up type 2 0.0024 0.0373 0.0373
Loa Loa (eye worm) TYRA-2 protein 0.0032 0.0594 0.0594
Brugia malayi nuclear hormone receptor 0.0012 0.0004 0.0004
Echinococcus granulosus neuropeptide receptor 0.0032 0.0594 0.0603

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 21.9661 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule agonists of the NFkB signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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