Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0152 | 0.488 | 0.6563 |
Onchocerca volvulus | Putative transporter | 0.003 | 0 | 0.5 |
Trypanosoma cruzi | hexose transporter | 0.0067 | 0.1467 | 1 |
Giardia lamblia | Sugar-proton symporter | 0.003 | 0 | 0.5 |
Echinococcus multilocularis | solute carrier family 2 facilitated glucose | 0.0216 | 0.7436 | 1 |
Mycobacterium tuberculosis | Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) | 0.003 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0067 | 0.1467 | 0.1973 |
Leishmania major | glucose transporter, lmgt1 | 0.0067 | 0.1467 | 1 |
Onchocerca volvulus | 0.003 | 0 | 0.5 | |
Trichomonas vaginalis | sugar transporter, putative | 0.0067 | 0.1467 | 0.1973 |
Onchocerca volvulus | 0.003 | 0 | 0.5 | |
Onchocerca volvulus | 0.003 | 0 | 0.5 | |
Trypanosoma cruzi | hexose transporter, putative | 0.0067 | 0.1467 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0152 | 0.488 | 0.6563 |
Echinococcus multilocularis | solute carrier family 2 facilitated glucose | 0.0216 | 0.7436 | 1 |
Onchocerca volvulus | 0.003 | 0 | 0.5 | |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.0216 | 0.7436 | 1 |
Trichomonas vaginalis | sugar transporter, putative | 0.0067 | 0.1467 | 0.1973 |
Trichomonas vaginalis | glucose transporter, putative | 0.0067 | 0.1467 | 0.1973 |
Trypanosoma brucei | glucose transporter, putative | 0.0067 | 0.1467 | 1 |
Leishmania major | glucose transporter, lmgt2 | 0.0067 | 0.1467 | 1 |
Mycobacterium ulcerans | sugar transporter | 0.003 | 0 | 0.5 |
Trypanosoma brucei | glucose transporter, putative | 0.0067 | 0.1467 | 1 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0164 | 0.537 | 0.7221 |
Leishmania major | glucose transporter, lmgt3 | 0.0067 | 0.1467 | 1 |
Trypanosoma brucei | THT1 - hexose transporter, putative | 0.0067 | 0.1467 | 1 |
Onchocerca volvulus | 0.003 | 0 | 0.5 | |
Plasmodium vivax | hexose transporter | 0.0216 | 0.7436 | 1 |
Trypanosoma brucei | glucose transporter, putative | 0.0067 | 0.1467 | 1 |
Onchocerca volvulus | 0.003 | 0 | 0.5 | |
Trypanosoma brucei | glucose transporter, putative | 0.0067 | 0.1467 | 1 |
Plasmodium falciparum | hexose transporter | 0.0216 | 0.7436 | 1 |
Trypanosoma brucei | glucose transporter 1E | 0.0067 | 0.1467 | 1 |
Trypanosoma cruzi | hexose transporter, putative | 0.0067 | 0.1467 | 1 |
Mycobacterium ulcerans | integral membrane transport protein | 0.003 | 0 | 0.5 |
Echinococcus multilocularis | solute carrier family 2 facilitated glucose | 0.0216 | 0.7436 | 1 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0152 | 0.488 | 0.6563 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0216 | 0.7436 | 1 |
Loa Loa (eye worm) | sugar transporter | 0.0216 | 0.7436 | 0.7436 |
Onchocerca volvulus | 0.003 | 0 | 0.5 | |
Onchocerca volvulus | 0.003 | 0 | 0.5 | |
Leishmania major | glucose transporter/membrane transporter D2, putative | 0.0067 | 0.1467 | 1 |
Onchocerca volvulus | 0.003 | 0 | 0.5 | |
Trypanosoma brucei | glucose transporter, putative | 0.0067 | 0.1467 | 1 |
Trypanosoma brucei | THT1 - hexose transporter, putative | 0.0067 | 0.1467 | 1 |
Trichomonas vaginalis | sugar transporter, putative | 0.0067 | 0.1467 | 0.1973 |
Brugia malayi | Sugar transporter family protein | 0.0216 | 0.7436 | 0.7436 |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.0216 | 0.7436 | 1 |
Schistosoma mansoni | glucose transport protein | 0.0216 | 0.7436 | 1 |
Onchocerca volvulus | 0.003 | 0 | 0.5 | |
Onchocerca volvulus | 0.003 | 0 | 0.5 | |
Echinococcus multilocularis | solute carrier family 2, facilitated glucose | 0.0216 | 0.7436 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0164 | 0.537 | 0.7221 |
Onchocerca volvulus | 0.003 | 0 | 0.5 | |
Trypanosoma brucei | glucose transporter 2A | 0.0067 | 0.1467 | 1 |
Echinococcus multilocularis | General substrate transporter | 0.0185 | 0.6219 | 0.8364 |
Trypanosoma brucei | glucose transporter, putative | 0.0067 | 0.1467 | 1 |
Trypanosoma cruzi | hexose transporter, putative | 0.0067 | 0.1467 | 1 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.028 | 1 | 1 |
Mycobacterium ulcerans | sugar-transport integral membrane protein SugI | 0.003 | 0 | 0.5 |
Giardia lamblia | Hexose transporter | 0.003 | 0 | 0.5 |
Schistosoma mansoni | thyroid hormone receptor | 0.0164 | 0.537 | 0.7221 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0067 | 0.1467 | 0.1973 |
Onchocerca volvulus | 0.003 | 0 | 0.5 | |
Onchocerca volvulus | 0.003 | 0 | 0.5 | |
Echinococcus granulosus | General substrate transporter | 0.0185 | 0.6219 | 0.8364 |
Trypanosoma brucei | glucose transporter, putative | 0.0067 | 0.1467 | 1 |
Mycobacterium ulcerans | fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT | 0.003 | 0 | 0.5 |
Trypanosoma cruzi | hexose transporter, putative | 0.0037 | 0.025 | 0.1706 |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.0216 | 0.7436 | 1 |
Schistosoma mansoni | glucose transport protein | 0.0216 | 0.7436 | 1 |
Schistosoma mansoni | glucose transport protein | 0.0216 | 0.7436 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0216 | 0.7436 | 1 |
Toxoplasma gondii | facilitative glucose transporter GT1 | 0.0216 | 0.7436 | 1 |
Onchocerca volvulus | 0.003 | 0 | 0.5 | |
Trichomonas vaginalis | glucose transporter, putative | 0.0067 | 0.1467 | 0.1973 |
Trypanosoma brucei | glucose transporter, putative | 0.0067 | 0.1467 | 1 |
Onchocerca volvulus | 0.003 | 0 | 0.5 | |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.0216 | 0.7436 | 1 |
Trypanosoma brucei | THT1 - hexose transporter, putative | 0.0067 | 0.1467 | 1 |
Wolbachia endosymbiont of Brugia malayi | major facilitator superfamily permease | 0.003 | 0 | 0.5 |
Mycobacterium tuberculosis | Probable conserved integral membrane transport protein | 0.003 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.