Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0029 | 0.1887 | 0.223 |
Trypanosoma cruzi | ISWI complex protein | 0.0017 | 0 | 0.5 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0022 | 0.0894 | 0.0667 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0018 | 0.0294 | 0.0366 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0018 | 0.0294 | 0.0366 |
Schistosoma mansoni | hypothetical protein | 0.0022 | 0.0894 | 0.1112 |
Echinococcus multilocularis | zinc finger protein | 0.0021 | 0.0717 | 0.0592 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0029 | 0.1887 | 0.033 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0024 | 0.1214 | 0.1287 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0029 | 0.1887 | 0.223 |
Leishmania major | hypothetical protein, conserved | 0.0017 | 0 | 0.5 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0029 | 0.1887 | 0.2348 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0018 | 0.0294 | 0.0366 |
Trypanosoma brucei | ISWI complex protein | 0.0017 | 0 | 0.5 |
Schistosoma mansoni | zinc finger protein | 0.0021 | 0.0717 | 0.0891 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0024 | 0.1214 | 0.1287 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.9283 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0029 | 0.1887 | 0.2348 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0029 | 0.1887 | 0.1772 |
Echinococcus granulosus | zinc finger protein | 0.0021 | 0.0717 | 0.0592 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0029 | 0.1887 | 0.223 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0018 | 0.0294 | 0.0366 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0029 | 0.1887 | 0.223 |
Trypanosoma cruzi | ISWI complex protein | 0.0017 | 0 | 0.5 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0029 | 0.1887 | 0.2348 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0019 | 0.0397 | 0.0114 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0065 | 0.7437 | 1 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0039 | 0.3456 | 0.4427 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0024 | 0.1214 | 0.151 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.4581 | 0.4769 |
Schistosoma mansoni | bromodomain containing protein | 0.0068 | 0.8037 | 1 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0039 | 0.3456 | 0.4427 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.3864 | 0.3972 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.4261 | 0.4413 |
Brugia malayi | Bromodomain containing protein | 0.0041 | 0.3853 | 0.2673 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0065 | 0.7437 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.