Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | cathepsin L-like protease | 0.015 | 1 | 1 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0039 | 0.1924 | 0.2968 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.015 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.002 | 0.053 | 0.053 |
Onchocerca volvulus | 0.0039 | 0.1924 | 1 | |
Brugia malayi | Cathepsin L-like precursor | 0.0039 | 0.1924 | 0.207 |
Plasmodium vivax | unspecified product | 0.002 | 0.053 | 0.2757 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.015 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0039 | 0.1924 | 0.2968 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0974 | 0.1048 |
Brugia malayi | Cathepsin L-like precursor | 0.0039 | 0.1924 | 0.207 |
Echinococcus multilocularis | cysteine protease | 0.0039 | 0.1924 | 0.2968 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0039 | 0.1924 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0039 | 0.1924 | 0.1924 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0039 | 0.1924 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0026 | 0.0974 | 0.0944 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0039 | 0.1924 | 0.2968 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.015 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.015 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0974 | 0.1048 |
Entamoeba histolytica | cysteine protease, putative | 0.0039 | 0.1924 | 0.2968 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.014 | 0.9296 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0039 | 0.1924 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.002 | 0.053 | 0.1015 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0039 | 0.1924 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0039 | 0.1924 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0039 | 0.1924 | 1 |
Onchocerca volvulus | 0.0039 | 0.1924 | 1 | |
Brugia malayi | Papain family cysteine protease containing protein | 0.0039 | 0.1924 | 0.207 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.014 | 0.9296 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0039 | 0.1924 | 1 |
Brugia malayi | cathepsin L-like precursor | 0.0026 | 0.0974 | 0.1048 |
Entamoeba histolytica | hypothetical protein | 0.0084 | 0.5225 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0084 | 0.5225 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0039 | 0.1924 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.002 | 0.053 | 0.1015 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.015 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0039 | 0.1924 | 1 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0026 | 0.0974 | 0.1048 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.015 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0039 | 0.1924 | 0.207 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.015 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0039 | 0.1924 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0039 | 0.1924 | 1 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0118 | 0.7656 | 0.7656 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0039 | 0.1924 | 0.2968 |
Brugia malayi | hypothetical protein | 0.0084 | 0.5225 | 0.5621 |
Echinococcus granulosus | cathepsin l1 | 0.0039 | 0.1924 | 0.2968 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0974 | 0.1048 |
Loa Loa (eye worm) | ctsf protein | 0.0039 | 0.1924 | 0.207 |
Brugia malayi | Papain family cysteine protease containing protein | 0.002 | 0.053 | 0.0571 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.015 | 1 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0039 | 0.1924 | 0.2968 |
Entamoeba histolytica | hypothetical protein | 0.0084 | 0.5225 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0026 | 0.0974 | 0.1864 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0039 | 0.1924 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0039 | 0.1924 | 0.2968 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0137 | 0.905 | 0.905 |
Schistosoma mansoni | hypothetical protein | 0.0084 | 0.5225 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0026 | 0.0974 | 0.1048 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.015 | 1 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0039 | 0.1924 | 1 |
Onchocerca volvulus | 0.0039 | 0.1924 | 1 | |
Brugia malayi | MH2 domain containing protein | 0.014 | 0.9296 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.015 | 1 | 1 |
Onchocerca volvulus | 0.0039 | 0.1924 | 1 | |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0039 | 0.1924 | 0.3682 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.002 | 0.053 | 0.053 |
Toxoplasma gondii | cathepsin CPL | 0.0039 | 0.1924 | 0.5 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.002 | 0.053 | 0.1015 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0084 | 0.5225 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0039 | 0.1924 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0039 | 0.1924 | 0.2968 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0039 | 0.1924 | 0.2968 |
Brugia malayi | Cathepsin L-like precursor | 0.0026 | 0.0974 | 0.1048 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0039 | 0.1924 | 1 |
Plasmodium vivax | vivapain-2 | 0.0039 | 0.1924 | 1 |
Onchocerca volvulus | 0.0039 | 0.1924 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0039 | 0.1924 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0039 | 0.1924 | 1 |
Loa Loa (eye worm) | cysteine protease | 0.0039 | 0.1924 | 0.207 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.015 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.1924 | 0.207 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0026 | 0.0974 | 0.0944 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0039 | 0.1924 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0039 | 0.1924 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0039 | 0.1924 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0039 | 0.1924 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.015 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0039 | 0.1924 | 1 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0039 | 0.1924 | 0.207 |
Loa Loa (eye worm) | fibroinase | 0.0039 | 0.1924 | 0.207 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0039 | 0.1924 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.015 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0039 | 0.1924 | 0.207 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0039 | 0.1924 | 0.207 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0084 | 0.5225 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.0974 | 0.3182 |
Plasmodium vivax | vivapain-1 | 0.002 | 0.053 | 0.2757 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.002 | 0.053 | 0.053 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0039 | 0.1924 | 0.3682 |
Leishmania major | cathepsin L-like protease | 0.015 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0039 | 0.1924 | 0.207 |
Plasmodium vivax | vivapain-3 | 0.002 | 0.053 | 0.2757 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0039 | 0.1924 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0039 | 0.1924 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0039 | 0.1924 | 0.2968 |
Brugia malayi | Papain family cysteine protease containing protein | 0.002 | 0.053 | 0.0571 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0039 | 0.1924 | 1 |
Onchocerca volvulus | 0.0039 | 0.1924 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0039 | 0.1924 | 1 |
Trypanosoma cruzi | cysteine protease, putative | 0.002 | 0.053 | 0.053 |
Onchocerca volvulus | 0.0039 | 0.1924 | 1 | |
Brugia malayi | Cathepsin L-like precursor | 0.0039 | 0.1924 | 0.207 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.015 | 1 | 1 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0084 | 0.5225 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.0974 | 0.3182 |
Plasmodium vivax | vivapain-2 | 0.0039 | 0.1924 | 1 |
Onchocerca volvulus | Cathepsin F homolog | 0.0039 | 0.1924 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0039 | 0.1924 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0039 | 0.1924 | 1 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.002 | 0.053 | 0.053 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.015 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0084 | 0.5225 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0039 | 0.1924 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.