Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0121 | 0.0154 | 0.0159 |
Loa Loa (eye worm) | hypothetical protein | 0.0324 | 0.0427 | 0.0447 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0013 | 0.0009 | 0.0007 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0298 | 0.0393 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.0051 | 0.0075 |
Loa Loa (eye worm) | hypothetical protein | 0.0324 | 0.0427 | 0.0447 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0324 | 0.0427 | 0.0624 |
Loa Loa (eye worm) | hypothetical protein | 0.0324 | 0.0427 | 0.0447 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0324 | 0.0427 | 0.0582 |
Schistosoma mansoni | hypothetical protein | 0.0013 | 0.0009 | 0.0012 |
Loa Loa (eye worm) | hypothetical protein | 0.0363 | 0.048 | 0.0502 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0324 | 0.0427 | 0.0582 |
Loa Loa (eye worm) | hypothetical protein | 0.0324 | 0.0427 | 0.0447 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0686 | 0.0917 | 0.0962 |
Loa Loa (eye worm) | hypothetical protein | 0.0686 | 0.0917 | 0.0961 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.0075 | 0.0102 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0686 | 0.0917 | 0.089 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0686 | 0.0917 | 0.0961 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 0.0051 | 0.0052 |
Loa Loa (eye worm) | hypothetical protein | 0.0363 | 0.048 | 0.0502 |
Echinococcus multilocularis | cpg binding protein | 0.003 | 0.0031 | 0.0045 |
Brugia malayi | hypothetical protein | 0.0324 | 0.0427 | 0.0447 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0686 | 0.0917 | 0.1338 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.7057 | 0.9511 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.0324 | 0.0427 | 0.0582 |
Schistosoma mansoni | thyroid hormone receptor | 0.0686 | 0.0917 | 0.1249 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0686 | 0.0917 | 0.1249 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0298 | 0.0393 | 1 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0324 | 0.0427 | 0.0447 |
Onchocerca volvulus | 0.0324 | 0.0427 | 0.04 | |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.006 | 0.0072 | 0.0098 |
Schistosoma mansoni | coup transcription factor | 0.0686 | 0.0917 | 0.1249 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0324 | 0.0427 | 0.0624 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0324 | 0.0427 | 0.0447 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0324 | 0.0427 | 0.0624 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0016 | 0.5 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0019 | 0.0016 | 0.0183 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0324 | 0.0427 | 0.04 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0363 | 0.048 | 0.0502 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0686 | 0.0917 | 0.1249 |
Schistosoma mansoni | cytochrome P450 | 0.0013 | 0.0009 | 0.0012 |
Loa Loa (eye worm) | hypothetical protein | 0.0686 | 0.0917 | 0.0961 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0324 | 0.0427 | 0.0582 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0019 | 0.0016 | 0.5 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0031 | 0.0042 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0016 | 0.0021 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0686 | 0.0917 | 0.1249 |
Loa Loa (eye worm) | hypothetical protein | 0.0121 | 0.0154 | 0.0159 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.0016 | 0.0183 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0054 | 0.0063 | 1 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0031 | 0.0042 |
Brugia malayi | cytochrome P450 | 0.0013 | 0.0009 | 0.0007 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0324 | 0.0427 | 0.0447 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0324 | 0.0427 | 0.0447 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.0075 | 0.0102 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0686 | 0.0917 | 0.0961 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.0075 | 0.0102 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0686 | 0.0917 | 0.0962 |
Echinococcus granulosus | tar DNA binding protein | 0.0063 | 0.0075 | 0.0102 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0686 | 0.0917 | 0.1338 |
Brugia malayi | Cytochrome P450 family protein | 0.0013 | 0.0009 | 0.0007 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0686 | 0.0917 | 0.1249 |
Schistosoma mansoni | zinc finger protein | 0.0324 | 0.0427 | 0.0582 |
Echinococcus granulosus | FTZ F1 alpha | 0.0686 | 0.0917 | 0.1249 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0028 | 0.0029 | 0.0028 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0298 | 0.0393 | 1 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0063 | 0.0075 | 0.0076 |
Brugia malayi | nuclear receptor RXR | 0.0324 | 0.0427 | 0.0447 |
Echinococcus granulosus | cytochrome P450 2K1 | 0.0013 | 0.0009 | 0.0012 |
Leishmania major | mitochondrial DNA polymerase beta | 0.0298 | 0.0393 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0686 | 0.0917 | 0.0962 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0686 | 0.0917 | 0.0962 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0686 | 0.0917 | 0.1249 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0686 | 0.0917 | 0.1338 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0002 | 0.0003 |
Loa Loa (eye worm) | hypothetical protein | 0.0686 | 0.0917 | 0.0961 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0019 | 0.0016 | 0.0183 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0324 | 0.0427 | 0.0582 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0324 | 0.0427 | 0.04 |
Brugia malayi | CXXC zinc finger family protein | 0.0028 | 0.0029 | 0.0028 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0686 | 0.0917 | 0.0961 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.0016 | 0.5 |
Schistosoma mansoni | nuclear hormone receptor | 0.0324 | 0.0427 | 0.0582 |
Brugia malayi | hypothetical protein | 0.0121 | 0.0154 | 0.0159 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0324 | 0.0427 | 0.0582 |
Brugia malayi | nuclear receptor RXR | 0.0363 | 0.048 | 0.0502 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0324 | 0.0427 | 0.0582 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.0016 | 0.0183 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0686 | 0.0917 | 0.0962 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0324 | 0.0427 | 0.0447 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0363 | 0.048 | 0.07 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.0051 | 0.007 |
Brugia malayi | Cytochrome P450 family protein | 0.0013 | 0.0009 | 0.0007 |
Loa Loa (eye worm) | hypothetical protein | 0.0686 | 0.0917 | 0.0961 |
Brugia malayi | nuclear receptor NHR-67 | 0.0324 | 0.0427 | 0.0447 |
Loa Loa (eye worm) | hypothetical protein | 0.0363 | 0.048 | 0.0502 |
Onchocerca volvulus | 0.0324 | 0.0427 | 0.04 | |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0686 | 0.0917 | 0.1249 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0324 | 0.0427 | 0.0582 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0686 | 0.0917 | 0.1249 |
Loa Loa (eye worm) | hypothetical protein | 0.0363 | 0.048 | 0.0502 |
Onchocerca volvulus | 0.0686 | 0.0917 | 0.089 | |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0042 | 0.0047 | 0.1003 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.0016 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0324 | 0.0427 | 0.0447 |
Toxoplasma gondii | hypothetical protein | 0.0048 | 0.0055 | 0.8606 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.0051 | 0.007 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0013 | 0.0009 | 0.0007 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.0051 | 0.0075 |
Loa Loa (eye worm) | hypothetical protein | 0.0324 | 0.0427 | 0.0447 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0042 | 0.0047 | 0.1003 |
Brugia malayi | nuclear hormone receptor | 0.7057 | 0.9511 | 1 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0686 | 0.0917 | 0.1249 |
Brugia malayi | nuclear receptor NHR-88 | 0.0686 | 0.0917 | 0.0962 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0019 | 0.0016 | 0.0014 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0324 | 0.0427 | 0.0447 |
Loa Loa (eye worm) | hypothetical protein | 0.0324 | 0.0427 | 0.0447 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.0075 | 0.0102 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0013 | 0.0009 | 0.0007 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0686 | 0.0917 | 0.1338 |
Toxoplasma gondii | exonuclease III APE | 0.0019 | 0.0016 | 0.129 |
Brugia malayi | Cytochrome P450 family protein | 0.0013 | 0.0009 | 0.0007 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0686 | 0.0917 | 0.1249 |
Brugia malayi | nuclear receptor NHR-88 | 0.0324 | 0.0427 | 0.0447 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0016 | 0.0021 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0686 | 0.0917 | 0.0962 |
Loa Loa (eye worm) | RNA binding protein | 0.0063 | 0.0075 | 0.0076 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0042 | 0.0047 | 0.1003 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0016 | 0.5 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0363 | 0.048 | 0.0502 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0324 | 0.0427 | 0.0447 |
Onchocerca volvulus | Huntingtin homolog | 0.0121 | 0.0154 | 0.0125 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0019 | 0.0016 | 0.5 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0686 | 0.0917 | 0.0962 |
Brugia malayi | conserved hypotetical protein | 0.0324 | 0.0427 | 0.0447 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0141 | 0.0181 | 0.4486 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0686 | 0.0917 | 0.0962 |
Loa Loa (eye worm) | hypothetical protein | 0.0324 | 0.0427 | 0.0447 |
Brugia malayi | ecdysone receptor | 0.0324 | 0.0427 | 0.0447 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0324 | 0.0427 | 0.0582 |
Brugia malayi | steroid hormone receptor | 0.0686 | 0.0917 | 0.0962 |
Loa Loa (eye worm) | hypothetical protein | 0.0686 | 0.0917 | 0.0961 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0019 | 0.0016 | 0.0362 |
Loa Loa (eye worm) | hypothetical protein | 0.0324 | 0.0427 | 0.0447 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0063 | 0.0075 | 0.0076 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0051 | 0.007 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0363 | 0.048 | 0.0654 |
Loa Loa (eye worm) | hypothetical protein | 0.0324 | 0.0427 | 0.0447 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0363 | 0.048 | 0.0654 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0686 | 0.0917 | 0.1338 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0686 | 0.0917 | 0.0961 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0019 | 0.0016 | 0.0014 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0686 | 0.0917 | 0.0962 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0042 | 0.0047 | 0.1003 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0141 | 0.0181 | 0.4486 |
Loa Loa (eye worm) | hypothetical protein | 0.0324 | 0.0427 | 0.0447 |
Loa Loa (eye worm) | hypothetical protein | 0.0324 | 0.0427 | 0.0447 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0686 | 0.0917 | 0.1338 |
Brugia malayi | hypothetical protein | 0.0324 | 0.0427 | 0.0447 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0324 | 0.0427 | 0.0447 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0051 | 0.007 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0686 | 0.0917 | 0.0962 |
Loa Loa (eye worm) | DR-78 | 0.0324 | 0.0427 | 0.0447 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0019 | 0.0016 | 0.0023 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.5446 | 0.7338 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0686 | 0.0917 | 0.0961 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.5083 | 0.6849 | 1 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0686 | 0.0917 | 0.1249 |
Echinococcus multilocularis | 0.0013 | 0.0009 | 0.0012 | |
Schistosoma mansoni | cpg binding protein | 0.0028 | 0.0029 | 0.0039 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0019 | 0.0016 | 0.5 |
Brugia malayi | hypothetical protein | 0.0363 | 0.048 | 0.0502 |
Brugia malayi | tailless protein | 0.0324 | 0.0427 | 0.0447 |
Mycobacterium ulcerans | hypothetical protein | 0.0157 | 0.0202 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0686 | 0.0917 | 0.0961 |
Brugia malayi | RNA binding protein | 0.0063 | 0.0075 | 0.0076 |
Loa Loa (eye worm) | hypothetical protein | 0.0324 | 0.0427 | 0.0447 |
Loa Loa (eye worm) | TAR-binding protein | 0.0063 | 0.0075 | 0.0076 |
Brugia malayi | TAR-binding protein | 0.0063 | 0.0075 | 0.0076 |
Mycobacterium leprae | putative cytochrome p450 | 0.0013 | 0.0009 | 0.5 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0019 | 0.0016 | 0.5 |
Loa Loa (eye worm) | cytochrome P450 | 0.0013 | 0.0009 | 0.0007 |
Schistosoma mansoni | nuclear hormone receptor | 0.0686 | 0.0917 | 0.1249 |
Mycobacterium leprae | Conserved hypothetical protein | 0.0013 | 0.0009 | 0.5 |
Echinococcus granulosus | cpg binding protein | 0.003 | 0.0031 | 0.0042 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.0075 | 0.0102 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0019 | 0.0016 | 0.0021 |
Brugia malayi | nuclear hormone receptor | 0.0686 | 0.0917 | 0.0962 |
Schistosoma mansoni | thyroid hormone receptor | 0.0686 | 0.0917 | 0.1249 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0324 | 0.0427 | 0.0624 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0686 | 0.0917 | 0.1338 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0045 | 0.0051 | 0.0052 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0363 | 0.048 | 0.0654 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0686 | 0.0917 | 0.0962 |
Loa Loa (eye worm) | hypothetical protein | 0.0686 | 0.0917 | 0.0961 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0686 | 0.0917 | 0.0962 |
Loa Loa (eye worm) | hypothetical protein | 0.0363 | 0.048 | 0.0502 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0051 | 0.007 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0686 | 0.0917 | 0.0962 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0019 | 0.0016 | 0.0362 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0002 | 0.0003 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0686 | 0.0917 | 0.089 |
Onchocerca volvulus | Huntingtin homolog | 0.0121 | 0.0154 | 0.0125 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0051 | 0.0059 | 0.1325 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0686 | 0.0917 | 0.1249 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0686 | 0.0917 | 0.1249 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0013 | 0.0009 | 0.0007 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0686 | 0.0917 | 0.0962 |
Schistosoma mansoni | nuclear receptor | 0.0324 | 0.0427 | 0.0582 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0157 | 0.0202 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0686 | 0.0917 | 0.0962 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0686 | 0.0917 | 0.0961 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0686 | 0.0917 | 0.0961 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0324 | 0.0427 | 0.0624 |
Schistosoma mansoni | nuclear receptor | 0.0324 | 0.0427 | 0.0582 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0686 | 0.0917 | 0.0962 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0141 | 0.0181 | 0.4486 |
Loa Loa (eye worm) | hypothetical protein | 0.6733 | 0.9074 | 0.9541 |
Brugia malayi | hypothetical protein | 0.0363 | 0.048 | 0.0502 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0686 | 0.0917 | 0.1249 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0363 | 0.048 | 0.0502 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0686 | 0.0917 | 0.1249 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0686 | 0.0917 | 0.0961 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.5446 | 0.7338 | 1 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0324 | 0.0427 | 0.0582 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0686 | 0.0917 | 0.1338 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0686 | 0.0917 | 0.0961 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0686 | 0.0917 | 0.1249 |
Brugia malayi | ecdysteroid receptor | 0.0686 | 0.0917 | 0.0962 |
Brugia malayi | Cytochrome P450 family protein | 0.0013 | 0.0009 | 0.0007 |
Echinococcus multilocularis | tar DNA binding protein | 0.0063 | 0.0075 | 0.0109 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0686 | 0.0917 | 0.1338 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | uM | Compound was tested for its ability to inhibit binding of arginine vasopressin to Vasopressin receptor (V1 subtype); ND is no data | ChEMBL. | No reference |
IC50 (binding) | 0 uM | Compound was tested for its ability to inhibit binding of arginine vasopressin to Vasopressin receptor (V1 subtype); ND is no data | ChEMBL. | No reference |
IC50 (binding) | > 100 uM | Compound was tested for its ability to inhibit binding of Oxytocin to its Oxytocin receptor in rat uterine tissue | ChEMBL. | No reference |
IC50 (binding) | > 100 uM | Compound was tested for its ability to inhibit binding of Oxytocin to its Oxytocin receptor in rat uterine tissue | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.