Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.02 | 0.5357 | 0.6548 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0014 | 0.0065 | 0.0079 |
Mycobacterium tuberculosis | Probable thioesterase TesA | 0.0044 | 0.0918 | 0.1199 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0014 | 0.0065 | 0.0079 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.02 | 0.5357 | 1 |
Giardia lamblia | Methyltransferase like 2 | 0.0016 | 0.0121 | 0.0225 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0014 | 0.0065 | 0.0079 |
Mycobacterium tuberculosis | Probable membrane bound polyketide synthase Pks6 | 0.0079 | 0.1909 | 0.2493 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0053 | 0.1187 | 0.9075 |
Schistosoma mansoni | gabp alpha | 0.0067 | 0.1579 | 0.193 |
Schistosoma mansoni | ap endonuclease | 0.0058 | 0.1308 | 0.1599 |
Schistosoma mansoni | hypothetical protein | 0.0072 | 0.1721 | 0.2104 |
Trypanosoma cruzi | beta-ketoacyl synthase family protein, putative | 0.0013 | 0.0045 | 0.0085 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0058 | 0.1308 | 0.1599 |
Schistosoma mansoni | cpg binding protein | 0.0061 | 0.1414 | 0.1729 |
Echinococcus multilocularis | GPCR, family 2 | 0.0033 | 0.0619 | 0.0619 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0053 | 0.1187 | 0.395 |
Brugia malayi | Pre-SET motif family protein | 0.0194 | 0.5196 | 0.6351 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks17 | 0.0013 | 0.0035 | 0.0046 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0033 | 0.062 | 0.1158 |
Brugia malayi | TAR-binding protein | 0.0134 | 0.3483 | 0.4258 |
Toxoplasma gondii | 3-oxoacyl-acyl-carrier protein synthase I/II, putative | 0.0013 | 0.0045 | 0.0151 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB | 0.0042 | 0.0875 | 0.2185 |
Mycobacterium ulcerans | class a beta-lactamase, BlaC | 0.0281 | 0.766 | 0.936 |
Mycobacterium tuberculosis | Probable multifunctional mycocerosic acid synthase membrane-associated Mas | 0.0056 | 0.1261 | 0.1647 |
Brugia malayi | Methyltransferase-like protein 4 | 0.0016 | 0.0121 | 0.0148 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0053 | 0.1187 | 0.9075 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsA | 0.0042 | 0.0875 | 0.102 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0058 | 0.1308 | 0.1599 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0053 | 0.1187 | 0.2216 |
Echinococcus granulosus | 3 oxoacyl acyl carrier protein synthase | 0.0013 | 0.0045 | 0.0045 |
Mycobacterium ulcerans | polyketide synthase | 0.0053 | 0.1168 | 0.138 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0016 | 0.0132 | 0.0132 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0029 | 0.0495 | 0.0604 |
Loa Loa (eye worm) | TAR-binding protein | 0.0134 | 0.3483 | 0.4258 |
Loa Loa (eye worm) | beta-ketoacyl synthase domain-containing protein | 0.0013 | 0.0045 | 0.0055 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0072 | 0.1721 | 0.2104 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0058 | 0.1308 | 0.2442 |
Loa Loa (eye worm) | hypothetical protein | 0.0197 | 0.529 | 0.6467 |
Brugia malayi | Beta-ketoacyl synthase, N-terminal domain containing protein | 0.0053 | 0.1168 | 0.1428 |
Loa Loa (eye worm) | fatty acid synthase | 0.0052 | 0.1148 | 0.1403 |
Mycobacterium tuberculosis | Conserved protein | 0.0016 | 0.0121 | 0.0158 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0033 | 0.062 | 0.0758 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsD | 0.0053 | 0.1168 | 0.138 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.02 | 0.5357 | 0.8997 |
Mycobacterium tuberculosis | Polyketide synthase Pks12 | 0.0056 | 0.1261 | 0.1647 |
Brugia malayi | AMP-binding enzyme family protein | 0.0049 | 0.107 | 0.1308 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0058 | 0.1308 | 0.1708 |
Plasmodium falciparum | 3-oxoacyl-acyl-carrier protein synthase I/II | 0.0013 | 0.0045 | 0.0347 |
Mycobacterium leprae | Polyketide synthase Pks13 | 0.0079 | 0.1909 | 0.5259 |
Schistosoma mansoni | kinase | 0.0102 | 0.256 | 0.3129 |
Mycobacterium ulcerans | polyketide synthase | 0.0056 | 0.1261 | 0.1495 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks9 | 0.003 | 0.0521 | 0.0681 |
Mycobacterium leprae | PROBABLE CONSERVED LIPOPROTEIN LPQF | 0.0135 | 0.3505 | 1 |
Trichomonas vaginalis | glutaminase, putative | 0.0299 | 0.8181 | 1 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0033 | 0.062 | 0.2065 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0033 | 0.062 | 0.062 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsE | 0.0035 | 0.066 | 0.0756 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0098 | 0.2449 | 0.2993 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE | 0.0035 | 0.066 | 0.1547 |
Onchocerca volvulus | Fatty acid synthase homolog | 0.0095 | 0.2371 | 0.3983 |
Mycobacterium ulcerans | lipoprotein LpqF | 0.0135 | 0.3505 | 0.4252 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0014 | 0.0065 | 0.0079 |
Brugia malayi | CXXC zinc finger family protein | 0.0061 | 0.1414 | 0.1729 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.002 | 0.0238 | 0.0238 |
Echinococcus multilocularis | geminin | 0.0157 | 0.4138 | 0.4138 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.02 | 0.5357 | 0.6548 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0014 | 0.0065 | 0.0079 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0016 | 0.0132 | 0.0132 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0053 | 0.1187 | 0.2216 |
Giardia lamblia | Kinase, PLK | 0.02 | 0.5357 | 1 |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.0049 | 0.107 | 0.1396 |
Trichomonas vaginalis | CAMK family protein kinase | 0.02 | 0.5357 | 0.6548 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0099 | 0.2485 | 0.3037 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0495 | 0.0604 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0053 | 0.1187 | 0.2216 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0014 | 0.0065 | 0.0079 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0058 | 0.1308 | 0.2442 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0033 | 0.0619 | 0.0619 |
Loa Loa (eye worm) | hypothetical protein | 0.0088 | 0.2187 | 0.2674 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.02 | 0.5357 | 1 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0033 | 0.062 | 0.1158 |
Mycobacterium leprae | Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas | 0.0056 | 0.1261 | 0.3332 |
Loa Loa (eye worm) | histone methyltransferase | 0.002 | 0.0238 | 0.0291 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0098 | 0.2449 | 0.2449 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0058 | 0.1308 | 0.1308 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0619 | 0.0757 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0033 | 0.062 | 0.062 |
Mycobacterium tuberculosis | Class a beta-lactamase BlaC | 0.0281 | 0.766 | 1 |
Brugia malayi | glutaminase DH11.1 | 0.0299 | 0.8181 | 1 |
Mycobacterium ulcerans | polyketide synthase MbtD | 0.0016 | 0.013 | 0.0104 |
Onchocerca volvulus | 0.0092 | 0.2278 | 0.3826 | |
Brugia malayi | Ets-domain containing protein | 0.0067 | 0.1579 | 0.193 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0014 | 0.0065 | 0.0079 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0014 | 0.0065 | 0.0079 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.1187 | 0.1451 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0033 | 0.0619 | 0.0619 |
Trichomonas vaginalis | set domain proteins, putative | 0.0221 | 0.5954 | 0.7278 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0016 | 0.0132 | 0.0132 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0098 | 0.2449 | 0.2449 |
Onchocerca volvulus | 0.0061 | 0.1414 | 0.2375 | |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0098 | 0.2449 | 0.2993 |
Mycobacterium tuberculosis | Polyketide synthase Pks13 | 0.0079 | 0.1909 | 0.2493 |
Schistosoma mansoni | tar DNA-binding protein | 0.0134 | 0.3483 | 0.4258 |
Mycobacterium tuberculosis | Probable fatty acid synthase Fas (fatty acid synthetase) | 0.0017 | 0.014 | 0.0183 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0058 | 0.1308 | 0.1599 |
Trichomonas vaginalis | CAMK family protein kinase | 0.02 | 0.5357 | 0.6548 |
Echinococcus granulosus | geminin | 0.0157 | 0.4138 | 0.4138 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.002 | 0.0231 | 0.0283 |
Echinococcus multilocularis | 3 oxoacyl (acyl carrier protein) synthase | 0.0013 | 0.0045 | 0.0045 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0033 | 0.062 | 0.2065 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0105 | 0.2671 | 0.3265 |
Schistosoma mansoni | ets-related | 0.0204 | 0.5467 | 0.6683 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0033 | 0.0619 | 0.0757 |
Brugia malayi | Pre-SET motif family protein | 0.0029 | 0.0495 | 0.0604 |
Leishmania major | hypothetical protein, conserved | 0.0016 | 0.0121 | 0.0225 |
Mycobacterium ulcerans | thioesterase | 0.0044 | 0.0918 | 0.1073 |
Schistosoma mansoni | hypothetical protein | 0.0157 | 0.4138 | 0.5058 |
Mycobacterium tuberculosis | Polyketide synthase Pks2 | 0.0051 | 0.1122 | 0.1465 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0098 | 0.2449 | 0.2449 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0619 | 0.0757 |
Schistosoma mansoni | hypothetical protein | 0.0157 | 0.4138 | 0.5058 |
Loa Loa (eye worm) | RNA binding protein | 0.0134 | 0.3483 | 0.4258 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0058 | 0.1308 | 0.2442 |
Loa Loa (eye worm) | glutaminase | 0.0299 | 0.8181 | 1 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0027 | 0.0427 | 0.0427 |
Schistosoma mansoni | 3-oxoacyl-[ACP] synthase | 0.0013 | 0.0045 | 0.0055 |
Brugia malayi | Fli-1 protein | 0.0204 | 0.5467 | 0.6683 |
Loa Loa (eye worm) | fli-1 protein | 0.0204 | 0.5467 | 0.6683 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.02 | 0.5357 | 0.5357 |
Brugia malayi | oxidoreductase, zinc-binding dehydrogenase family protein | 0.01 | 0.251 | 0.3069 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1302 | 0.1591 |
Mycobacterium ulcerans | polyketide synthase Pks13 | 0.0079 | 0.1909 | 0.2291 |
Mycobacterium ulcerans | fatty acid synthase Fas | 0.0017 | 0.014 | 0.0116 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.1721 | 0.2104 |
Trichomonas vaginalis | CAMK family protein kinase | 0.02 | 0.5357 | 0.6548 |
Loa Loa (eye worm) | glutaminase 2 | 0.0299 | 0.8181 | 1 |
Onchocerca volvulus | 0.0221 | 0.5954 | 1 | |
Toxoplasma gondii | beta-ketoacyl synthase, N-terminal domain-containing protein | 0.0034 | 0.0642 | 0.2135 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0099 | 0.2485 | 0.3037 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0105 | 0.2671 | 0.3265 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsD | 0.0053 | 0.1168 | 0.1525 |
Onchocerca volvulus | Rap guanine nucleotide exchange factor 1 homolog | 0.0197 | 0.529 | 0.8885 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0016 | 0.0132 | 0.0161 |
Trypanosoma brucei | beta lactamase | 0.0135 | 0.3505 | 0.6542 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC | 0.0056 | 0.1261 | 0.3332 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0363 | 1 | 1 |
Mycobacterium ulcerans | multifunctional mycocerosic acid synthase membrane-associated Mas | 0.0056 | 0.1261 | 0.1495 |
Brugia malayi | Isocitrate dehydrogenase | 0.0033 | 0.062 | 0.0758 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0098 | 0.2449 | 0.2993 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0029 | 0.0495 | 0.0604 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0053 | 0.1168 | 0.138 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0058 | 0.1308 | 1 |
Plasmodium vivax | SET domain protein, putative | 0.0029 | 0.0495 | 0.3781 |
Schistosoma mansoni | cpg binding protein | 0.0065 | 0.1514 | 0.185 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0058 | 0.1308 | 0.2442 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0016 | 0.0132 | 0.0132 |
Brugia malayi | hypothetical protein | 0.0034 | 0.0649 | 0.0793 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0033 | 0.0619 | 0.0757 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks1 | 0.0038 | 0.0746 | 0.0974 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0619 | 0.0757 |
Brugia malayi | isocitrate dehydrogenase | 0.0033 | 0.062 | 0.0758 |
Mycobacterium leprae | PROBABLE THIOESTERASE TESA | 0.0044 | 0.0918 | 0.2313 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0058 | 0.1308 | 0.2442 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0029 | 0.0495 | 0.0604 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0509 | 0.0622 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0058 | 0.1308 | 0.2442 |
Echinococcus granulosus | GA binding protein alpha chain | 0.0067 | 0.1579 | 0.1579 |
Trichomonas vaginalis | CAMK family protein kinase | 0.02 | 0.5357 | 0.6548 |
Echinococcus multilocularis | tar DNA binding protein | 0.0134 | 0.3483 | 0.3483 |
Echinococcus multilocularis | cpg binding protein | 0.0065 | 0.1514 | 0.1514 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0033 | 0.062 | 0.1158 |
Mycobacterium tuberculosis | Hypothetical protein | 0.0016 | 0.0121 | 0.0158 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0033 | 0.0619 | 0.0619 |
Trypanosoma brucei | polo-like protein kinase | 0.02 | 0.5357 | 1 |
Schistosoma mansoni | cpg binding protein | 0.0065 | 0.1514 | 0.185 |
Schistosoma mansoni | hypothetical protein | 0.0024 | 0.035 | 0.0428 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0134 | 0.3483 | 0.4258 |
Schistosoma mansoni | tar DNA-binding protein | 0.0134 | 0.3483 | 0.4258 |
Schistosoma mansoni | tar DNA-binding protein | 0.0134 | 0.3483 | 0.4258 |
Toxoplasma gondii | type I fatty acid synthase, putative | 0.0056 | 0.1261 | 0.4198 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0033 | 0.0619 | 0.0619 |
Echinococcus multilocularis | GA binding protein alpha chain | 0.0067 | 0.1579 | 0.1579 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0058 | 0.1308 | 0.1308 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsC | 0.0053 | 0.1168 | 0.1525 |
Trypanosoma brucei | beta-ketoacyl-ACP synthase | 0.0013 | 0.0045 | 0.0085 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0033 | 0.062 | 0.0758 |
Brugia malayi | AMP-binding enzyme family protein | 0.0016 | 0.013 | 0.0159 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.02 | 0.5357 | 1 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0033 | 0.062 | 0.062 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsA | 0.0053 | 0.1168 | 0.1525 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.002 | 0.0238 | 0.0238 |
Brugia malayi | N-terminal motif family protein | 0.0197 | 0.529 | 0.6467 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0029 | 0.0495 | 0.0495 |
Schistosoma mansoni | tar DNA-binding protein | 0.0134 | 0.3483 | 0.4258 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0014 | 0.0065 | 0.0079 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsB | 0.0042 | 0.0875 | 0.102 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.02 | 0.5357 | 1 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0053 | 0.1187 | 0.9075 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0029 | 0.0495 | 0.0495 |
Chlamydia trachomatis | 3-oxoacyl-ACP synthase | 0.0013 | 0.0045 | 0.5 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0033 | 0.062 | 0.1158 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0033 | 0.062 | 0.062 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0058 | 0.1308 | 0.1552 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0117 | 0.3004 | 1 |
Echinococcus granulosus | cpg binding protein | 0.0065 | 0.1514 | 0.1514 |
Mycobacterium tuberculosis | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) | 0.0033 | 0.062 | 0.081 |
Loa Loa (eye worm) | acyl carrier protein | 0.0024 | 0.0358 | 0.0438 |
Mycobacterium leprae | Probable polyketide synthase Pks1 | 0.0056 | 0.1261 | 0.3332 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.02 | 0.5357 | 0.5357 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0014 | 0.0065 | 0.0079 |
Brugia malayi | Beta-ketoacyl synthase, N-terminal domain containing protein | 0.0013 | 0.0045 | 0.0055 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0029 | 0.0495 | 0.1646 |
Mycobacterium tuberculosis | Probable conserved lipoprotein LpqF | 0.0135 | 0.3505 | 0.4575 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0061 | 0.1414 | 0.1729 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0058 | 0.1308 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0105 | 0.2671 | 0.3265 |
Leishmania major | hypothetical protein, conserved | 0.0053 | 0.1187 | 0.2216 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0053 | 0.1168 | 0.138 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0014 | 0.0065 | 0.0079 |
Trichomonas vaginalis | helicase, putative | 0.0014 | 0.0065 | 0.0079 |
Trichomonas vaginalis | CAMK family protein kinase | 0.02 | 0.5357 | 0.6548 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0619 | 0.0757 |
Plasmodium vivax | 3-oxoacyl-[acyl-carrier-protein] synthase i/ii, putative | 0.0013 | 0.0045 | 0.0347 |
Toxoplasma gondii | exonuclease III APE | 0.0058 | 0.1308 | 0.4353 |
Schistosoma mansoni | ap endonuclease | 0.0058 | 0.1308 | 0.1599 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0016 | 0.0121 | 0.0148 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0033 | 0.062 | 0.1158 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0029 | 0.0495 | 0.0495 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0033 | 0.062 | 0.062 |
Mycobacterium ulcerans | thioesterase TesA | 0.0044 | 0.0918 | 0.1073 |
Echinococcus granulosus | GPCR family 2 | 0.0033 | 0.0619 | 0.0619 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0033 | 0.062 | 0.4744 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0033 | 0.062 | 0.4744 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0058 | 0.1308 | 1 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsC | 0.0056 | 0.1261 | 0.1495 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0014 | 0.0065 | 0.0079 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0014 | 0.0065 | 0.0079 |
Loa Loa (eye worm) | D-ets-4 DNA binding domain-containing protein | 0.0067 | 0.1579 | 0.193 |
Toxoplasma gondii | AMP-binding enzyme domain-containing protein | 0.0027 | 0.0427 | 0.142 |
Mycobacterium ulcerans | glutaminase | 0.0299 | 0.8181 | 1 |
Schistosoma mansoni | glutaminase | 0.0299 | 0.8181 | 1 |
Mycobacterium ulcerans | polyketide synthase Pks9 | 0.0035 | 0.066 | 0.0756 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0049 | 0.107 | 0.1308 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0105 | 0.2671 | 0.3265 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0029 | 0.0495 | 0.0604 |
Mycobacterium tuberculosis | Polyketide synthetase MbtD (polyketide synthase) | 0.0016 | 0.013 | 0.017 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0098 | 0.2449 | 0.2993 |
Mycobacterium tuberculosis | Polyketide synthetase MbtC (polyketide synthase) | 0.0018 | 0.0184 | 0.0241 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0014 | 0.0065 | 0.0079 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0619 | 0.0757 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0098 | 0.2449 | 0.2993 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0098 | 0.2449 | 0.2449 |
Schistosoma mansoni | tar DNA-binding protein | 0.0134 | 0.3483 | 0.4258 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0033 | 0.0619 | 0.0757 |
Schistosoma mansoni | serine/threonine protein kinase | 0.02 | 0.5357 | 0.6548 |
Trichomonas vaginalis | CAMK family protein kinase | 0.02 | 0.5357 | 0.6548 |
Toxoplasma gondii | type I fatty acid synthase, putative | 0.0037 | 0.0736 | 0.245 |
Brugia malayi | hypothetical protein | 0.0053 | 0.1187 | 0.1451 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks15 | 0.0021 | 0.0275 | 0.0359 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0024 | 0.035 | 0.035 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks5 | 0.0051 | 0.1122 | 0.1465 |
Brugia malayi | Ets-domain containing protein | 0.0067 | 0.1579 | 0.193 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD | 0.0053 | 0.1168 | 0.3056 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks7 | 0.0056 | 0.1261 | 0.1647 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0134 | 0.3483 | 0.4258 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0033 | 0.062 | 0.062 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks8 | 0.0043 | 0.0895 | 0.1168 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0024 | 0.035 | 0.035 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0014 | 0.0065 | 0.0079 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0014 | 0.0065 | 0.0079 |
Echinococcus granulosus | tar DNA binding protein | 0.0134 | 0.3483 | 0.3483 |
Onchocerca volvulus | 0.0049 | 0.107 | 0.1796 | |
Brugia malayi | RNA binding protein | 0.0134 | 0.3483 | 0.4258 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0014 | 0.0065 | 0.0079 |
Trypanosoma cruzi | beta-ketoacyl synthase family protein, putative | 0.0013 | 0.0045 | 0.0085 |
Leishmania major | beta-ketoacyl synthase family protein, putative,3-oxoacyl-acyl carrier protein synthase ii, putative | 0.0013 | 0.0045 | 0.0085 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0194 | 0.5196 | 0.6351 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0058 | 0.1308 | 0.1599 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0058 | 0.1308 | 1 |
Schistosoma mansoni | methyltransferase-related | 0.0016 | 0.0121 | 0.0148 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA | 0.0053 | 0.1168 | 0.3056 |
Onchocerca volvulus | 0.0029 | 0.0495 | 0.0831 | |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0131 | 0.34 | 0.4156 |
Trichomonas vaginalis | CAMK family protein kinase | 0.02 | 0.5357 | 0.6548 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0053 | 0.1168 | 0.138 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MST (functional) | Antimalarial activity against Plasmodium berghei infected in mouse assessed as host survival time at 640 mg/kg, sc treated after 3 days of infection (Rvb = 6.2 +/- 0.5 days) | ChEMBL. | 353282 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.