Detailed information for compound 1894668

Basic information

Technical information
  • TDR Targets ID: 1894668
  • Name: 1-(2-chloroethyl)-3-[(1S,3R)-3-hydroxycyclohe xyl]-1-nitrosourea
  • MW: 249.695 | Formula: C9H16ClN3O3
  • H donors: 2 H acceptors: 3 LogP: 1.05 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: ClCCN(C(=O)N[C@H]1CCC[C@H](C1)O)N=O
  • InChi: 1S/C9H16ClN3O3/c10-4-5-13(12-16)9(15)11-7-2-1-3-8(14)6-7/h7-8,14H,1-6H2,(H,11,15)/t7-,8+/m0/s1
  • InChiKey: RLVBEHFQVMKVOD-JGVFFNPUSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 1-(2-chloroethyl)-3-[(1S,3R)-3-hydroxycyclohexyl]-1-nitroso-urea
  • 56323-45-6
  • NSC 253945
  • NSC253945
  • Urea, N-(2-chloroethyl)-N'-(3-hydroxycyclohexyl)-N-nitroso-, cis-
  • cis-3-Hydroxy CCNU
  • cis-3-OH CCNU

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium ulcerans 3-oxoacyl-(acyl carrier protein) synthase II 0.0013 0.0003 0.0009
Mycobacterium ulcerans polyketide synthase Pks13 0.0075 0.0533 0.1901
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.002 0.0065 0.0126
Brugia malayi Serotonin receptor 0.0036 0.0198 0.0226
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0036 0.0203 0.0408
Toxoplasma gondii Adenosine/AMP deaminase domain-containing protein 0.0344 0.2802 0.5702
Leishmania major aminopeptidase P1, putative,metallo-peptidase, Clan MG, Family M24 0.0074 0.0519 0.1051
Plasmodium falciparum AMP deaminase, putative 0.0112 0.0843 0.1711
Giardia lamblia Cytidine deaminase 0.0052 0.0339 0.0643
Entamoeba histolytica methionine aminopeptidase, putative 0.0594 0.4913 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0065 0.007
Toxoplasma gondii type I fatty acid synthase, putative 0.0036 0.0199 0.04
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0036 0.0198 0.0398
Entamoeba histolytica adenosylhomocysteinase, putative 0.014 0.1075 0.2171
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0074 0.0519 0.0509
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.0072 0.0082
Plasmodium falciparum methionine aminopeptidase 1a, putative 0.0074 0.0519 0.1051
Leishmania major glycosyl hydrolase-like protein 0.0014 0.001 0.0015
Echinococcus granulosus 7TM GPCR rhodopsin 0.0036 0.0198 0.0398
Schistosoma mansoni methionyl aminopeptidase 1 (M24 family) 0.0074 0.0519 0.1051
Echinococcus granulosus g protein coupled receptor 0.0036 0.0198 0.0398
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.0105 0.0373
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.002 0.0065 0.007
Brugia malayi Pre-SET motif family protein 0.0151 0.1174 0.1338
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0043 0.0155
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0003 0.0001
Trichomonas vaginalis cytidine deaminase, putative 0.0052 0.0339 0.0329
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0093 0.0083
Mycobacterium ulcerans fatty acid synthase Fas 0.0016 0.003 0.0105
Brugia malayi jmjC domain containing protein 0.0039 0.0224 0.0255
Loa Loa (eye worm) hypothetical protein 0.0032 0.0165 0.0185
Onchocerca volvulus 0.0036 0.0198 0.0198
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0036 0.0198 0.0398
Brugia malayi chromobox protein homolog 3 0.0041 0.024 0.0273
Giardia lamblia Glyceraldehyde 3-phosphate dehydrogenase 0.0132 0.1015 0.2027
Trichomonas vaginalis chromobox protein, putative 0.0044 0.0266 0.0256
Brugia malayi hypothetical protein 0.0036 0.0198 0.0226
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0036 0.0198 0.0278
Mycobacterium ulcerans dipeptidase PepE 0.0074 0.0519 0.185
Trypanosoma brucei AMP deaminase, putative 0.0112 0.0843 0.1711
Brugia malayi RNA, U transporter 1 0.0082 0.0589 0.0671
Loa Loa (eye worm) neuropeptide F receptor 0.0036 0.0198 0.0223
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0391 0.3203 0.3648
Echinococcus multilocularis tumor protein p63 0.033 0.2684 0.3812
Schistosoma mansoni adenosylhomocysteinase 0.0086 0.0625 0.1268
Echinococcus multilocularis neuropeptide Y receptor 0.0036 0.0198 0.0278
Loa Loa (eye worm) hypothetical protein 0.0036 0.0198 0.0223
Loa Loa (eye worm) hypothetical protein 0.0232 0.1856 0.2112
Loa Loa (eye worm) hypothetical protein 0.0018 0.0052 0.0056
Onchocerca volvulus Alhambra homolog 0.0029 0.0142 0.0142
Leishmania major AMP deaminase, putative,amp deaminase-like protein 0.0112 0.0843 0.1711
Loa Loa (eye worm) hypothetical protein 0.0036 0.0198 0.0223
Onchocerca volvulus AMP deaminase 2 homolog 0.0112 0.0843 0.0843
Brugia malayi G protein-coupled receptor 0.0036 0.0198 0.0226
Brugia malayi metallopeptidase family M24 containing protein 0.0074 0.0519 0.0591
Leishmania major CAAX prenyl protease 2, putative,peptidase with unknown catalytic mechanism (family U48) 0.0187 0.1477 0.3003
Echinococcus granulosus chromobox protein 1 0.0073 0.0509 0.1032
Mycobacterium tuberculosis Conserved protein 0.0015 0.0024 0.0087
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.004 0.0076
Echinococcus granulosus zinc finger protein 0.0021 0.0075 0.0147
Toxoplasma gondii proliferation-associated protein 2G4, putative 0.0074 0.0519 0.1051
Plasmodium falciparum aminopeptidase P 0.0074 0.0519 0.1051
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.002 0.0065 0.007
Plasmodium vivax methionine aminopeptidase 1c, putative 0.0074 0.0519 0.1051
Brugia malayi Melatonin receptor type 1A 0.0036 0.0198 0.0226
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0049 0.0306 0.0348
Schistosoma mansoni adenosylhomocysteinase 0.0086 0.0625 0.1268
Trypanosoma brucei glucosidase, putative 0.0036 0.0203 0.0408
Loa Loa (eye worm) metallopeptidase family M24 containing protein 0.0074 0.0519 0.0588
Schistosoma mansoni opsin-like receptor 0.0036 0.0198 0.0398
Loa Loa (eye worm) hypothetical protein 0.0253 0.2031 0.2312
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.002 0.0065 0.0088
Toxoplasma gondii creatinase domain-containing protein 0.0074 0.0519 0.1051
Trichomonas vaginalis Citrate lyase beta chain, putative 0.005 0.0315 0.0305
Trypanosoma brucei Metallopeptidase family M24, putative 0.0074 0.0519 0.1051
Mycobacterium ulcerans polyketide synthase MbtD 0.0016 0.0027 0.0095
Leishmania major GTP-binding protein, putative 0.0021 0.0075 0.0147
Echinococcus multilocularis peregrin 0.0032 0.0162 0.0227
Brugia malayi AKH receptor 0.0036 0.0198 0.0226
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0138 0.1066 0.1511
Leishmania major glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0132 0.1015 0.2062
Echinococcus granulosus neuropeptide Y receptor 0.0036 0.0198 0.0398
Brugia malayi hypothetical protein 0.0253 0.2031 0.2315
Echinococcus multilocularis g protein coupled receptor 0.0036 0.0198 0.0278
Onchocerca volvulus 0.0054 0.0355 0.0355
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0036 0.0198 0.0278
Loa Loa (eye worm) hypothetical protein 0.0026 0.0114 0.0127
Toxoplasma gondii methionine aminopeptidase 2, putative 0.0594 0.4913 1
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0132 0.1015 0.2062
Echinococcus granulosus mitogen activated protein kinase 3 0.0051 0.0329 0.0664
Loa Loa (eye worm) hypothetical protein 0.0017 0.0036 0.0038
Schistosoma mansoni hypothetical protein 0.0268 0.2156 0.4386
Trypanosoma brucei metallo-peptidase, Clan MG, Family M24 0.0594 0.4913 1
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0036 0.0198 0.0223
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.0132 0.1015 0.1439
Schistosoma mansoni adenosine deaminase-related 0.0344 0.2802 0.5702
Echinococcus granulosus methionyl aminopeptidase 2 0.0594 0.4913 1
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0036 0.0198 0.0398
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0132 0.1015 0.1006
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0061 0.0414 0.0585
Giardia lamblia Hypothetical protein 0.0187 0.1477 0.2972
Schistosoma mansoni intermediate filament proteins 0.0026 0.0118 0.0235
Leishmania major glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0132 0.1015 0.2062
Brugia malayi putative neuropeptide receptor 0.0036 0.0198 0.0226
Trypanosoma cruzi AMP deaminase, putative 0.0112 0.0843 0.1711
Entamoeba histolytica hypothetical protein 0.0073 0.051 0.102
Onchocerca volvulus 0.0036 0.0198 0.0198
Trypanosoma brucei S-adenosylhomocysteine hydrolase, putative 0.014 0.1075 0.2183
Echinococcus granulosus fmrfamide receptor 0.0036 0.0198 0.0398
Mycobacterium tuberculosis Probable adenosine deaminase Add (adenosine aminohydrolase) 0.0344 0.2802 1
Leishmania major transcription factor-like protein 0.0074 0.0519 0.1051
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.0132 0.1015 0.2062
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.002 0.0065 0.007
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0025 0.0105 0.0373
Loa Loa (eye worm) hypothetical protein 0.0014 0.001 0.0009
Echinococcus multilocularis mitogen activated protein kinase 0.0051 0.0329 0.0464
Wolbachia endosymbiont of Brugia malayi glyceraldehyde-3-phosphate dehydrogenase, GapA 0.0132 0.1015 1
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.005 0.0322 0.115
Toxoplasma gondii glyceraldehyde-3-phosphate dehydrogenase GAPDH2 0.0132 0.1015 0.2062
Treponema pallidum glyceraldehyde 3-phosphate dehydrogenase (gap) 0.0132 0.1015 0.3504
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0051 0.0329 0.0664
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0329 0.0319
Echinococcus granulosus neuropeptide s receptor 0.0505 0.4166 0.8479
Schistosoma mansoni zinc finger protein 0.0015 0.0025 0.0045
Schistosoma mansoni Tr4/Tr2 (homologue) 0.002 0.0065 0.0126
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0018 0.0051 0.0098
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0051 0.0329 0.0664
Onchocerca volvulus 0.0452 0.3715 0.3715
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative 0.0041 0.0243 0.0488
Schistosoma mansoni biogenic amine receptor 0.0036 0.0198 0.0398
Mycobacterium leprae Probable polyketide synthase Pks1 0.0054 0.0349 0.1243
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0065 0.0073
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0075 0.0147
Mycobacterium ulcerans methionine aminopeptidase MapB 0.0074 0.0519 0.185
Brugia malayi latrophilin 2 splice variant baaae 0.0268 0.2156 0.2458
Schistosoma mansoni hypothetical protein 0.0036 0.0198 0.0398
Plasmodium vivax adenosylhomocysteinase(S-adenosyl-L-homocystein e hydrolase), putative 0.014 0.1075 0.2183
Trypanosoma cruzi Metallopeptidase family M24/FACT complex subunit (SPT16/CDC68)/Histone chaperone Rttp106-like, putative 0.0074 0.0519 0.1051
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0036 0.0198 0.0398
Plasmodium vivax SET domain protein, putative 0.0151 0.1174 0.2385
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0036 0.0198 0.0398
Loa Loa (eye worm) hypothetical protein 0.0168 0.1318 0.1499
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0036 0.0198 0.0278
Schistosoma mansoni aminopeptidase P homologue (M24 family) 0.0074 0.0519 0.1051
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0025 0.0105 0.0373
Entamoeba histolytica acyl-CoA synthetase, putative 0.003 0.0148 0.028
Trichomonas vaginalis adenosylhomocysteinase, putative 0.014 0.1075 0.1065
Trypanosoma cruzi Metallopeptidase family M24, putative 0.0074 0.0519 0.1051
Echinococcus granulosus rhodopsin orphan GPCR 0.0036 0.0198 0.0398
Brugia malayi TAR-binding protein 0.0074 0.0523 0.0596
Echinococcus granulosus neuropeptide receptor 0.0036 0.0198 0.0398
Mycobacterium ulcerans hypothetical protein 0.0039 0.0222 0.0792
Brugia malayi Nuclear hormone receptor family member nhr-49 0.002 0.0065 0.0073
Loa Loa (eye worm) glyceraldehyde-3-phosphate dehydrogenase 0.0091 0.0668 0.0759
Loa Loa (eye worm) hypothetical protein 0.0036 0.0198 0.0223
Toxoplasma gondii methionine aminopeptidase 0.0074 0.0519 0.1051
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0105 0.0373
Loa Loa (eye worm) hypothetical protein 0.0041 0.024 0.0271
Onchocerca volvulus 0.0095 0.0697 0.0697
Echinococcus granulosus GPCR family 2 0.0124 0.0942 0.1913
Trichomonas vaginalis set domain proteins, putative 0.1196 1 1
Onchocerca volvulus 0.0074 0.0519 0.0518
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0073 0.051 0.0721
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0036 0.0198 0.0398
Schistosoma mansoni methyltransferase-related 0.0015 0.0024 0.0044
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0046 0.0282 0.0272
Brugia malayi RE15519p 0.0036 0.0198 0.0226
Brugia malayi Pre-SET motif family protein 0.1051 0.8774 1
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0012 0 0.0001
Chlamydia trachomatis hypothetical protein 0.0039 0.0222 0.2166
Echinococcus multilocularis G-protein coupled receptor, putative 0.0036 0.0198 0.0278
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0018 0.0051 0.0476
Onchocerca volvulus Huntingtin homolog 0.0253 0.2031 0.2031
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0105 0.0119
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0074 0.0519 0.0509
Echinococcus granulosus tar DNA binding protein 0.0074 0.0523 0.106
Echinococcus granulosus rhodopsin orphan GPCR 0.0036 0.0198 0.0398
Trichomonas vaginalis ran, putative 0.0021 0.0075 0.0065
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.0049 0.0309 0.1103
Loa Loa (eye worm) hypothetical protein 0.0036 0.0198 0.0223
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.024 0.023
Brugia malayi Methionine aminopeptidase protein type I 0.0074 0.0519 0.0591
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0051 0.0041
Schistosoma mansoni AMP deaminase 0.0112 0.0843 0.1711
Mycobacterium tuberculosis Methionine aminopeptidase MapA (map) (peptidase M) (MetAP) 0.0074 0.0519 0.1851
Schistosoma mansoni hypothetical protein 0.0124 0.0942 0.1913
Echinococcus multilocularis allatostatin A receptor 0.0036 0.0198 0.0278
Brugia malayi PHD-finger family protein 0.0013 0.0006 0.0007
Echinococcus granulosus 7tm_1 domain containing protein 0.0036 0.0198 0.0398
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0151 0.1174 0.2385
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0075 0.0085
Onchocerca volvulus 0.0048 0.0304 0.0304
Trypanosoma cruzi Metallopeptidase family M24, putative 0.0074 0.0519 0.1051
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0073 0.051 0.1033
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0284 0.2293 0.4664
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0075 0.0147
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.014 0.0278
Loa Loa (eye worm) hypothetical protein 0.0036 0.0198 0.0223
Loa Loa (eye worm) hypothetical protein 0.0036 0.0198 0.0223
Echinococcus multilocularis rhodopsin orphan GPCR 0.0036 0.0198 0.0278
Toxoplasma gondii hypothetical protein 0.0039 0.0222 0.0447
Brugia malayi initiation factor 2-associated protein. 0.0594 0.4913 0.5599
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB 0.0041 0.0239 0.0852
Schistosoma mansoni chromobox protein 0.0073 0.0509 0.1032
Loa Loa (eye worm) hypothetical protein 0.0036 0.0198 0.0223
Loa Loa (eye worm) latrophilin receptor protein 2 0.0124 0.0942 0.1071
Schistosoma mansoni hypothetical protein 0.0036 0.0198 0.0398
Trypanosoma brucei Xaa-Pro aminopeptidase, putative 0.0074 0.0519 0.1051
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0132 0.1015 0.1006
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0036 0.0198 0.0398
Leishmania major hypothetical protein, conserved 0.0074 0.0519 0.1051
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.0051 0.0058
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0203 0.0408
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0118 0.0135
Brugia malayi PHD-finger family protein 0.0029 0.0142 0.0162
Trypanosoma cruzi adenosine monophosphate deaminase, putative 0.0112 0.0843 0.1711
Brugia malayi hypothetical protein 0.0036 0.0198 0.0226
Leishmania major adenosine monophosphate deaminase, putative,AMP deaminase, putative 0.0112 0.0843 0.1711
Schistosoma mansoni jumonji/arid domain-containing protein 0.0039 0.0224 0.0451
Echinococcus granulosus geminin 0.0177 0.1388 0.2821
Schistosoma mansoni bromodomain containing protein 0.0065 0.0445 0.09
Trypanosoma brucei metallo-peptidase, Clan MG, Family M24 0.0074 0.0519 0.1051
Loa Loa (eye worm) hypothetical protein 0.0232 0.1856 0.2112
Trichomonas vaginalis maltase-glucoamylase, putative 0.0036 0.0203 0.0193
Schistosoma mansoni importin beta-1 0.0029 0.014 0.0278
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.004 0.0076
Mycobacterium tuberculosis Probable adenosylhomocysteinase SahH (S-adenosyl-L-homocysteine hydrolase) (adohcyase) 0.014 0.1075 0.3834
Onchocerca volvulus Huntingtin homolog 0.0253 0.2031 0.2031
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.005 0.0315 0.1125
Leishmania major aminopeptidase P, putative,metallo-peptidase, Clan MG, Family M24 0.0074 0.0519 0.1051
Brugia malayi AMP-binding enzyme family protein 0.0054 0.0355 0.0405
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0132 0.1015 0.2062
Onchocerca volvulus 0.0112 0.0843 0.0843
Echinococcus multilocularis neutral alpha glucosidase AB 0.0036 0.0203 0.0285
Onchocerca volvulus 0.0036 0.0198 0.0198
Onchocerca volvulus Dipeptidase C homolog 0.0074 0.0519 0.0518
Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase, putative 0.0087 0.0629 0.1275
Schistosoma mansoni neuropeptide f receptor 76f 0.0036 0.0198 0.0398
Schistosoma mansoni growth hormone secretagogue receptor 0.0036 0.0198 0.0398
Echinococcus multilocularis orexin receptor type 2 0.0036 0.0198 0.0278
Echinococcus granulosus xaa Pro dipeptidase 0.0074 0.0519 0.1051
Wolbachia endosymbiont of Brugia malayi Xaa-Pro aminopeptidase 0.0074 0.0519 0.5095
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0203 0.0193
Loa Loa (eye worm) hypothetical protein 0.0086 0.0621 0.0704
Echinococcus multilocularis jumonji domain containing protein 0.0041 0.0239 0.0335
Echinococcus granulosus tm gpcr rhodopsin 0.0036 0.0198 0.0398
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.002 0.0065 0.0088
Mycobacterium tuberculosis Polyketide synthetase MbtC (polyketide synthase) 0.0017 0.0042 0.0151
Toxoplasma gondii type I fatty acid synthase, putative 0.0055 0.0357 0.0722
Onchocerca volvulus 0.0036 0.0198 0.0198
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0594 0.4913 0.4907
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0124 0.0942 0.1336
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0054 0.0349 0.1243
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0138 0.1066 0.2165
Loa Loa (eye worm) RecQ helicase 0.0021 0.0072 0.0079
Echinococcus multilocularis lamin dm0 0.0026 0.0118 0.0164
Echinococcus granulosus rhodopsin orphan GPCR 0.0036 0.0198 0.0398
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0036 0.0198 0.0398
Echinococcus granulosus rhodopsin orphan GPCR 0.0036 0.0198 0.0398
Brugia malayi photoreceptor-specific nuclear receptor 0.002 0.0065 0.0073
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0132 0.1015 0.2062
Mycobacterium tuberculosis Probable cytoplasmic peptidase PepQ 0.0074 0.0519 0.1851
Echinococcus multilocularis dnaJ subfamily B 0.0409 0.3353 0.4763
Plasmodium falciparum glyceraldehyde-3-phosphate dehydrogenase 0.0132 0.1015 0.2062
Loa Loa (eye worm) steroid hormone receptor 0.002 0.0065 0.007
Loa Loa (eye worm) fatty acid synthase 0.005 0.0316 0.0358
Echinococcus multilocularis g protein coupled receptor 0.0036 0.0198 0.0278
Schistosoma mansoni biogenic amine (5HT) receptor 0.0036 0.0198 0.0398
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.0142 0.0284
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.002 0.0065 0.007
Echinococcus multilocularis geminin 0.0177 0.1388 0.1969
Loa Loa (eye worm) heterochromatin protein 1 0.0073 0.0509 0.0577
Schistosoma mansoni proliferation-associated protein 2G4 38kDa (M24 family) 0.0074 0.0519 0.1051
Loa Loa (eye worm) hypothetical protein 0.002 0.0065 0.007
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0284 0.2293 0.3255
Mycobacterium tuberculosis Polyketide synthase Pks2 0.0049 0.0309 0.1103
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0105 0.0207
Trypanosoma cruzi metallo- peptidase, Clan MG, Family M24 0.0074 0.0519 0.1051
Loa Loa (eye worm) hypothetical protein 0.0036 0.0198 0.0223
Trypanosoma brucei AMP deaminase, putative 0.0112 0.0843 0.1711
Entamoeba histolytica CAAX amino terminal protease family 0.0039 0.0222 0.0432
Schistosoma mansoni amine GPCR 0.0036 0.0198 0.0398
Echinococcus multilocularis neuropeptides capa receptor 0.0036 0.0198 0.0278
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative 0.0041 0.0243 0.0488
Entamoeba histolytica acyl-coA synthetase, putative 0.0025 0.0105 0.0192
Plasmodium vivax adenosine/AMP deaminase, putative 0.0112 0.0843 0.1711
Schistosoma mansoni hypothetical protein 0.0409 0.3353 0.6823
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0051 0.0329 0.0664
Loa Loa (eye worm) hypothetical protein 0.0036 0.0198 0.0223
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0018 0.0051 0.0182
Mycobacterium tuberculosis Probable polyketide synthase Pks15 0.002 0.0068 0.0243
Entamoeba histolytica hypothetical protein 0.0023 0.0093 0.017
Schistosoma mansoni proliferation-associated protein 2G4 38kDa (M24 family) 0.0074 0.0519 0.1051
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0036 0.0198 0.0223
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.024 0.024
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0151 0.1174 0.2385
Echinococcus multilocularis lysine specific demethylase 5A 0.0035 0.0194 0.0272
Echinococcus multilocularis FTZ F1 alpha 0.002 0.0065 0.0088
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.005 0.0322 0.0367
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0014 0.001 0.0015
Trypanosoma brucei methionine aminopeptidase 2, putative 0.0594 0.4913 1
Giardia lamblia Kinase, CMGC MAPK 0.0051 0.0329 0.0623
Mycobacterium ulcerans cytoplasmic peptidase PepQ 0.0074 0.0519 0.185
Mycobacterium tuberculosis Probable thioesterase TesA 0.0042 0.0251 0.0896
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0051 0.0329 0.0372
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0051 0.0329 0.0664
Brugia malayi nuclear hormone receptor 0.002 0.0065 0.0073
Schistosoma mansoni peptidase 0.0074 0.0519 0.1051
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0036 0.0198 0.0398
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0036 0.0198 0.0398
Echinococcus multilocularis rhodopsin orphan GPCR 0.0036 0.0198 0.0278
Brugia malayi Dopamine receptor 0.0036 0.0198 0.0226
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.0033 0.0178 0.0634
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0138 0.1066 0.2165
Mycobacterium ulcerans Type I modular polyketide synthase 0.005 0.0322 0.1149
Entamoeba histolytica CAAX amino terminal protease family 0.0039 0.0222 0.0432
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0132 0.1015 0.2062
Echinococcus granulosus methionine aminopeptidase type I 0.0074 0.0519 0.1051
Schistosoma mansoni opsin-like receptor 0.0036 0.0198 0.0398
Loa Loa (eye worm) hypothetical protein 0.0048 0.0304 0.0343
Brugia malayi Bromodomain containing protein 0.0038 0.022 0.025
Onchocerca volvulus 0.0036 0.0198 0.0198
Plasmodium falciparum importin beta, putative 0.0029 0.014 0.0278
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0036 0.0198 0.0398
Schistosoma mansoni adenosine deaminase 0.0344 0.2802 0.5702
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0203 0.0393
Entamoeba histolytica aminopeptidase, putative 0.0074 0.0519 0.1037
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0203 0.0193
Loa Loa (eye worm) hypothetical protein 0.0018 0.0052 0.0056
Leishmania major glyceraldehyde-3-phosphate dehydrogenase-like protein 0.0087 0.0629 0.1275
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0036 0.0198 0.0398
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0051 0.0098
Trypanosoma cruzi metallo-peptidase, Clan MG, Family M24 0.0594 0.4913 1
Mycobacterium ulcerans adenosine deaminase 0.0344 0.2802 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0051 0.0041
Entamoeba histolytica hypothetical protein 0.0073 0.051 0.102
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.005 0.0315 0.1125
Brugia malayi hypothetical protein 0.0036 0.0198 0.0226
Brugia malayi GnHR receptor homolog 0.0036 0.0198 0.0226
Echinococcus granulosus somatostatin receptor 0.0036 0.0198 0.0398
Trypanosoma brucei methionine aminopeptidase, putative 0.0074 0.0519 0.1051
Trichomonas vaginalis cytidine deaminase, putative 0.0052 0.0339 0.0329
Echinococcus granulosus rhodopsin orphan GPCR 0.0036 0.0198 0.0398
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0105 0.0207
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0014 0.0018 0.003
Echinococcus multilocularis xaa pro aminopeptidase 0.0074 0.0519 0.0733
Echinococcus multilocularis neuropeptide receptor A26 0.0505 0.4166 0.5919
Schistosoma mansoni thyroid hormone receptor 0.002 0.0065 0.0126
Schistosoma mansoni amine GPCR 0.0036 0.0198 0.0398
Brugia malayi CHD4 protein 0.0015 0.0026 0.003
Echinococcus granulosus G protein coupled receptor 139 0.0036 0.0198 0.0398
Schistosoma mansoni myosin xvIII 0.0036 0.0198 0.0398
Schistosoma mansoni cpg binding protein 0.0029 0.0139 0.0276
Echinococcus granulosus tm gpcr rhodopsin 0.0036 0.0198 0.0398
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0051 0.0329 0.0664
Toxoplasma gondii glyceraldehyde-3-phosphate dehydrogenase GAPDH1 0.0132 0.1015 0.2062
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.0329 0.0664
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0132 0.1015 0.2062
Loa Loa (eye worm) hypothetical protein 0.0087 0.0629 0.0714
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0036 0.0198 0.0278
Trypanosoma brucei hypothetical protein, conserved 0.0431 0.3539 0.7202
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0013 0.0005 0.0004
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0074 0.0519 0.0509
Loa Loa (eye worm) hypothetical protein 0.0036 0.0198 0.0223
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0087 0.0629 0.062
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0329 0.0319
Schistosoma mansoni Xaa-Pro dipeptidase (M24 family) 0.0074 0.0519 0.1051
Schistosoma mansoni hypothetical protein 0.0177 0.1388 0.2821
Brugia malayi Latrophilin receptor protein 2 0.0124 0.0942 0.1074
Brugia malayi hypothetical protein 0.0036 0.0198 0.0226
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0015 0.0017
Toxoplasma gondii AMP deaminase 0.0112 0.0843 0.1711
Onchocerca volvulus 0.0029 0.0139 0.0138
Loa Loa (eye worm) hypothetical protein 0.0036 0.0198 0.0223
Echinococcus multilocularis chromobox protein 1 0.0073 0.0509 0.072
Echinococcus granulosus hypothetical protein 0.0036 0.0198 0.0398
Echinococcus multilocularis methionyl aminopeptidase 1 (M24 family) 0.0074 0.0519 0.0733
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.0051 0.0055
Trypanosoma cruzi AMP deaminase, putative 0.0112 0.0843 0.1711
Onchocerca volvulus 0.0025 0.0105 0.0104
Loa Loa (eye worm) hypothetical protein 0.0036 0.0198 0.0223
Onchocerca volvulus Protein ultraspiracle homolog 0.002 0.0065 0.0064
Mycobacterium leprae PROBABLE METHIONINE AMINOPEPTIDASE MAPB (MAP) (PEPTIDASE M) 0.0074 0.0519 0.185
Brugia malayi ORL1-like opioid receptor 0.0036 0.0198 0.0226
Echinococcus granulosus FTZ F1 alpha 0.002 0.0065 0.0126
Echinococcus multilocularis methionyl aminopeptidase 1 (M24 family) 0.0074 0.0519 0.0733
Brugia malayi larval opioid receptor 0.0036 0.0198 0.0226
Brugia malayi cytidine deaminase, identical 0.0052 0.0339 0.0386
Onchocerca volvulus 0.0026 0.0118 0.0118
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.002 0.0065 0.007
Schistosoma mansoni lozenge 0.0057 0.0375 0.0758
Schistosoma mansoni adenosylhomocysteinase 0.0086 0.0625 0.1268
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0036 0.0198 0.0223
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.002 0.0065 0.0126
Mycobacterium tuberculosis Methionine aminopeptidase MapB (map) (peptidase M) 0.0074 0.0519 0.1851
Loa Loa (eye worm) hypothetical protein 0.0452 0.3715 0.4233
Plasmodium falciparum adenosylhomocysteinase 0.014 0.1075 0.2183
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0168 0.1318 0.187
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0096 0.0704 0.0802
Schistosoma mansoni tar DNA-binding protein 0.0074 0.0523 0.106
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.007 0.0077
Schistosoma mansoni lamin 0.0026 0.0118 0.0235
Echinococcus multilocularis neuropeptide s receptor 0.0505 0.4166 0.5919
Loa Loa (eye worm) hypothetical protein 0.0036 0.0198 0.0223
Trypanosoma cruzi S-adenosylhomocysteine hydrolase, putative 0.014 0.1075 0.2183
Schistosoma mansoni neuropeptide receptor 0.0036 0.0198 0.0398
Loa Loa (eye worm) jmjC domain-containing protein 0.0039 0.0224 0.0252
Mycobacterium tuberculosis Dipeptidase PepE 0.0074 0.0519 0.1851
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.004 0.0053
Loa Loa (eye worm) hypothetical protein 0.0028 0.0135 0.015
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0132 0.1015 0.2062
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0308 0.2497 0.2844
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0074 0.0519 0.0509
Trypanosoma cruzi S-adenosylhomocysteine hydrolase, putative 0.014 0.1075 0.2183
Mycobacterium leprae PROBABLE CYTIDINE DEAMINASE CDD (CYTIDINE AMINOHYDROLASE) (CYTIDINE NUCLEOSIDE DEAMINASE) 0.0052 0.0339 0.1208
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.0054 0.0349 0.1243
Trypanosoma cruzi cytidine deaminase-like protein, putative 0.0052 0.0339 0.0684
Loa Loa (eye worm) hypothetical protein 0.005 0.0318 0.036
Brugia malayi RNA recognition motif domain containing protein 0.0074 0.0523 0.0596
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0105 0.0192
Brugia malayi Methyltransferase-like protein 4 0.0015 0.0024 0.0027
Schistosoma mansoni hypothetical protein 0.0049 0.0306 0.0617
Trypanosoma cruzi metallo-peptidase, Clan MG, Family M24, putative 0.0074 0.0519 0.1051
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0203 0.0193
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0054 0.0355 0.0402
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0036 0.0198 0.0278
Echinococcus granulosus tumor protein p63 0.033 0.2684 0.546
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0036 0.0198 0.0198
Echinococcus granulosus neutral alpha glucosidase AB 0.0036 0.0203 0.0408
Echinococcus multilocularis FACT complex subunit SPT16 0.0074 0.0519 0.0733
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0075 0.0147
Schistosoma mansoni amine GPCR 0.0036 0.0198 0.0398
Brugia malayi putative neuropeptide receptor NPR1 0.0036 0.0198 0.0226
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0594 0.4913 0.4907
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0203 0.0193
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0051 0.0041
Echinococcus granulosus peptide allatostatin:somatostatin 0.0036 0.0198 0.0398
Mycobacterium tuberculosis Probable integral membrane protein 0.0039 0.0222 0.0793
Brugia malayi Adenosylhomocysteinase 0.014 0.1075 0.1225
Trypanosoma brucei metallo-peptidase, Clan MG, Family M24 0.0074 0.0519 0.1051
Loa Loa (eye worm) hypothetical protein 0.0036 0.0198 0.0223
Echinococcus multilocularis mitogen activated protein kinase 3 0.0051 0.0329 0.0464
Echinococcus multilocularis rhodopsin orphan GPCR 0.0036 0.0198 0.0278
Leishmania major cytidine deaminase-like protein 0.0052 0.0339 0.0684
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0594 0.4913 0.4907
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0051 0.0098
Loa Loa (eye worm) hypothetical protein 0.0036 0.0198 0.0223
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0018 0.0052 0.0184
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.002 0.0065 0.007
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0075 0.0082
Onchocerca volvulus 0.0036 0.0198 0.0198
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0012 0 0.0001
Echinococcus granulosus g-protein coupled receptor 0.0036 0.0198 0.0398
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0041 0.0239 0.0852
Mycobacterium ulcerans polyketide synthase MbtC 0.0013 0.0003 0.0009
Mycobacterium ulcerans S-adenosyl-L-homocysteine hydrolase 0.014 0.1075 0.3834
Loa Loa (eye worm) hypothetical protein 0.0036 0.0198 0.0223
Brugia malayi AMP-binding enzyme family protein 0.0017 0.0035 0.004
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.002 0.0065 0.0126
Onchocerca volvulus Methionine aminopeptidase 2 homolog 0.0594 0.4913 0.4913
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.005 0.0322 0.1149
Loa Loa (eye worm) methionine aminopeptidase type I 0.0074 0.0519 0.0588
Leishmania major AMP deaminase, putative,adenosine monophosphate deaminase-like protein 0.0112 0.0843 0.1711
Brugia malayi MH2 domain containing protein 0.0134 0.1029 0.1173
Loa Loa (eye worm) glyceraldehyde 3-phosphate dehydrogenase 0.0087 0.0629 0.0714
Plasmodium falciparum methionine aminopeptidase 1b, putative 0.0074 0.0519 0.1051
Schistosoma mansoni methionyl aminopeptidase 2 (M24 family) 0.0594 0.4913 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0018 0.0051 0.0098
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0036 0.0198 0.0398
Mycobacterium tuberculosis Probable cytidine deaminase Cdd (cytidine aminohydrolase) (cytidine nucleoside deaminase) 0.0052 0.0339 0.1208
Leishmania major aminopeptidase P1, putative,metallo-peptidase, Clan MG, Family M24 0.0074 0.0519 0.1051
Onchocerca volvulus 0.0036 0.0198 0.0198
Trypanosoma cruzi hypothetical protein, conserved 0.0431 0.3539 0.7202
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0051 0.0041
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0036 0.0198 0.0398
Plasmodium vivax proliferation-associated protein 2g4, putative 0.0074 0.0519 0.1051
Schistosoma mansoni hypothetical protein 0.0015 0.0025 0.0045
Onchocerca volvulus Fatty acid synthase homolog 0.0091 0.0664 0.0664
Echinococcus granulosus AMP deaminase 2 0.0112 0.0843 0.1711
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0065 0.0088
Trichomonas vaginalis Clan U, family U48, CaaX prenyl peptidase 2-like 0.0187 0.1477 0.1468
Echinococcus multilocularis zinc finger protein 0.0021 0.0075 0.0103
Brugia malayi Nuclear hormone receptor family member nhr-41 0.002 0.0065 0.0073
Giardia lamblia Xaa-Pro dipeptidase 0.0074 0.0519 0.1011
Loa Loa (eye worm) hypothetical protein 0.0025 0.0105 0.0116
Schistosoma mansoni neuropeptide receptor 0.0036 0.0198 0.0398
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.0075 0.0533 0.1902
Onchocerca volvulus Bile acid receptor homolog 0.002 0.0065 0.0064
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.005 0.0322 0.1149
Loa Loa (eye worm) hypothetical protein 0.0036 0.0198 0.0223
Schistosoma mansoni family U48 unassigned peptidase (U48 family) 0.0187 0.1477 0.3003
Trypanosoma brucei methionine aminopeptidase, type I, putative 0.0074 0.0519 0.1051
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0138 0.1066 0.1511
Plasmodium vivax peptidase, putative 0.0074 0.0519 0.1051
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0036 0.0198 0.0223
Echinococcus multilocularis adenosylhomocysteinase 0.014 0.1075 0.1524
Loa Loa (eye worm) hypothetical protein 0.0036 0.0198 0.0223
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0036 0.0198 0.0398
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0036 0.0198 0.0278
Toxoplasma gondii methionine aminopeptidase, type i, putative 0.0074 0.0519 0.1051
Schistosoma mansoni jumonji/arid domain-containing protein 0.0039 0.0224 0.0451
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0074 0.0523 0.0593
Loa Loa (eye worm) hypothetical protein 0.0036 0.0198 0.0223
Brugia malayi neuropeptide F receptor 0.0036 0.0198 0.0226
Entamoeba histolytica Xaa-Pro dipeptidase, putative 0.0074 0.0519 0.1037
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.0087 0.0629 0.1276
Echinococcus multilocularis importin subunit beta 1 0.0029 0.014 0.0194
Schistosoma mansoni cpg binding protein 0.0032 0.0169 0.0337
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0036 0.0198 0.0398
Echinococcus multilocularis chromobox protein 1 0.0073 0.0509 0.072
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0093 0.0083
Trichomonas vaginalis adenosine deaminase, putative 0.0344 0.2802 0.2795
Loa Loa (eye worm) hypothetical protein 0.0071 0.0494 0.0559
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0044 0.0266 0.0266
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0036 0.0198 0.0278
Brugia malayi MAP kinase sur-1 0.0051 0.0329 0.0375
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0168 0.1318 0.2679
Brugia malayi Nuclear hormone receptor family member nhr-14 0.002 0.0065 0.0073
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0018 0.0051 0.0097
Treponema pallidum methionine aminopeptidase (map) 0.0074 0.0519 0.17
Plasmodium falciparum protease, putative 0.0039 0.0222 0.0447
Treponema pallidum adenosine deaminase 0.0344 0.2802 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0051 0.0041
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0132 0.1015 0.2062
Mycobacterium ulcerans cytidine deaminase 0.0052 0.0339 0.1208
Mycobacterium tuberculosis Polyketide synthase Pks13 0.0075 0.0533 0.1902
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0036 0.0198 0.0226
Echinococcus multilocularis serotonin receptor 0.0036 0.0198 0.0278
Loa Loa (eye worm) hypothetical protein 0.0452 0.3715 0.4233
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0051 0.0041
Mycobacterium ulcerans glyceraldehyde 3-phosphate dehydrogenase Gap 0.0132 0.1015 0.3622
Schistosoma mansoni opsin-like receptor 0.0036 0.0198 0.0398
Echinococcus granulosus intermediate filament protein 0.0026 0.0118 0.0235
Chlamydia trachomatis glyceraldehyde-3-phosphate dehydrogenase 0.0132 0.1015 1
Schistosoma mansoni hypothetical protein 0.0124 0.0942 0.1913
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, cytosolic 0.0132 0.1015 0.2062
Mycobacterium ulcerans polyketide synthase 0.005 0.0322 0.1149
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0043 0.0155
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.014 0.0278
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.0051 0.0098
Leishmania major S-adenosylhomocysteine hydrolase 0.014 0.1075 0.2183
Loa Loa (eye worm) acyl carrier protein 0.0023 0.0092 0.0102
Loa Loa (eye worm) hypothetical protein 0.0344 0.2802 0.3192
Onchocerca volvulus 0.0032 0.0165 0.0165
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0026 0.0015
Mycobacterium tuberculosis Probable conserved integral membrane protein 0.0039 0.0222 0.0793
Trypanosoma brucei Facilitates chromatin transcription complex subunit spt16 0.0074 0.0519 0.1051
Loa Loa (eye worm) hypothetical protein 0.0041 0.024 0.027
Trypanosoma cruzi metallo-peptidase, Clan MG, Family M24 0.0074 0.0519 0.1051
Loa Loa (eye worm) hypothetical protein 0.0036 0.0198 0.0223
Echinococcus granulosus tachykinin peptides receptor 99D 0.0036 0.0198 0.0398
Echinococcus granulosus neuropeptides capa receptor 0.0036 0.0198 0.0398
Echinococcus multilocularis CAAX prenyl protease 2 0.0187 0.1477 0.2096
Echinococcus granulosus neuropeptide Y receptor 0.0036 0.0198 0.0398
Echinococcus granulosus retinoic acid receptor rxr beta a 0.002 0.0065 0.0126
Brugia malayi metallopeptidase family M24 containing protein 0.0074 0.0519 0.0591
Schistosoma mansoni hypothetical protein 0.0021 0.007 0.0137
Onchocerca volvulus 0.0036 0.0198 0.0198
Schistosoma mansoni tar DNA-binding protein 0.0074 0.0523 0.106
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0036 0.0198 0.0398
Brugia malayi Bromodomain containing protein 0.0032 0.0162 0.0185
Toxoplasma gondii peptidase D, putative 0.0074 0.0519 0.1051
Entamoeba histolytica hypothetical protein, conserved 0.0074 0.0519 0.1037
Loa Loa (eye worm) hypothetical protein 0.0112 0.0843 0.0958
Loa Loa (eye worm) hypothetical protein 0.0074 0.0519 0.0588
Echinococcus granulosus adenosylhomocysteinase 0.014 0.1075 0.2183
Brugia malayi Tachykinin-like peptides receptor 99D 0.0036 0.0198 0.0226
Leishmania major alpha glucosidase II subunit, putative 0.0036 0.0203 0.0408
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0203 0.0408
Toxoplasma gondii methionine aminopeptidase 0.0074 0.0519 0.1051
Brugia malayi G protein-coupled receptor F59B2.13 0.0036 0.0198 0.0226
Schistosoma mansoni thyroid hormone receptor 0.002 0.0065 0.0126
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0132 0.1015 0.2062
Echinococcus granulosus rhodopsin orphan GPCR 0.0036 0.0198 0.0398
Echinococcus granulosus allatostatin A receptor 0.0036 0.0198 0.0398
Echinococcus multilocularis rhodopsin orphan GPCR 0.0036 0.0198 0.0278
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0041 0.0243 0.0488
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0164 0.1281 0.1457
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.0142 0.0198
Toxoplasma gondii Adenosine/AMP deaminase domain-containing protein 0.0344 0.2802 0.5702
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0036 0.0198 0.0278
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0051 0.0041
Schistosoma mansoni alpha-glucosidase 0.0141 0.1088 0.221
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0036 0.0198 0.0278
Leishmania major hypothetical protein, conserved 0.0015 0.0024 0.0044
Loa Loa (eye worm) runx1 0.0057 0.0375 0.0424
Leishmania major methionine aminopeptidase 2, putative 0.0594 0.4913 1
Schistosoma mansoni steroid hormone receptor ad4bp 0.002 0.0065 0.0126
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0013 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0036 0.0198 0.0223
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0138 0.1066 0.2165
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0132 0.1015 0.2062
Brugia malayi Glycosyl hydrolases family 31 protein 0.0014 0.001 0.0012
Schistosoma mansoni alpha-1 adrenergic receptor 0.0036 0.0198 0.0398
Loa Loa (eye worm) hypothetical protein 0.0187 0.1477 0.1681
Loa Loa (eye worm) histone methyltransferase 0.0014 0.0018 0.0017
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0329 0.0319
Schistosoma mansoni transcription factor LCR-F1 0.0073 0.051 0.1033
Echinococcus granulosus lamin dm0 0.0026 0.0118 0.0235
Trypanosoma cruzi peptidase with unknown catalytic mechanism (family U48) 0.0187 0.1477 0.3003
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.0054 0.0349 0.1243
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0093 0.0083
Echinococcus multilocularis g-protein coupled receptor 0.0036 0.0198 0.0278
Trypanosoma brucei adenosine monophosphate deaminase, putative 0.0112 0.0843 0.1711
Loa Loa (eye worm) hypothetical protein 0.0551 0.4553 0.5188
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0036 0.0198 0.0278
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.002 0.0065 0.0088
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0036 0.0198 0.0398
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0139 0.0129
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0024 0.01 0.0138
Schistosoma mansoni adenosylhomocysteinase 0.0086 0.0625 0.1268
Brugia malayi Adenosine/AMP deaminase family protein 0.0344 0.2802 0.3194
Loa Loa (eye worm) hypothetical protein 0.0036 0.0198 0.0223
Trypanosoma brucei AMP deaminase, putative 0.0112 0.0843 0.1711
Mycobacterium ulcerans hypothetical protein 0.0039 0.0222 0.0792
Trypanosoma cruzi AMP deaminase, putative 0.0112 0.0843 0.1711
Loa Loa (eye worm) hypothetical protein 0.0026 0.0118 0.0132
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0075 0.0147
Loa Loa (eye worm) transcription factor SMAD2 0.0134 0.1029 0.117
Trypanosoma brucei glycosyl hydrolase-like protein 0.0014 0.001 0.0015
Echinococcus multilocularis survival motor neuron protein 1 0.0238 0.1906 0.2706
Schistosoma mansoni tar DNA-binding protein 0.0074 0.0523 0.106
Loa Loa (eye worm) hypothetical protein 0.0268 0.2156 0.2455
Entamoeba histolytica CAAX prenyl protease family 0.0187 0.1477 0.2992
Schistosoma mansoni cpg binding protein 0.0032 0.0169 0.0337
Chlamydia trachomatis aminopeptidase P 0.0074 0.0519 0.5095
Trypanosoma brucei ISWI complex protein 0.0015 0.0025 0.0045
Echinococcus granulosus sex peptide receptor 0.0036 0.0198 0.0398
Echinococcus multilocularis musashi 0.0026 0.0118 0.0164
Loa Loa (eye worm) hypothetical protein 0.0018 0.0052 0.0056
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0014 0.0015 0.0025
Trichomonas vaginalis chromobox protein, putative 0.0073 0.0509 0.05
Onchocerca volvulus FACT complex subunit SPT16 homolog 0.0074 0.0519 0.0518
Schistosoma mansoni alpha-glucosidase 0.0141 0.1088 0.221
Brugia malayi hypothetical protein 0.0036 0.0198 0.0226
Mycobacterium tuberculosis Hypothetical protein 0.0015 0.0024 0.0087
Echinococcus multilocularis fmrfamide receptor 0.0036 0.0198 0.0278
Mycobacterium ulcerans 3-oxoacyl-(acyl carrier protein) synthase II 0.0013 0.0003 0.0009
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.0054 0.0349 0.1244
Toxoplasma gondii exonuclease III APE 0.0018 0.0051 0.0098
Brugia malayi glyceraldehyde 3-phosphate dehydrogenase 0.0041 0.0243 0.0276
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.014 0.0278
Brugia malayi ecdysteroid receptor 0.002 0.0065 0.0073
Brugia malayi SET domain containing protein 0.0018 0.0048 0.0055
Onchocerca volvulus Adenosine deaminase homolog 0.0344 0.2802 0.2802
Brugia malayi CXXC zinc finger family protein 0.0029 0.0139 0.0158
Loa Loa (eye worm) hypothetical protein 0.002 0.0065 0.007
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0105 0.0119
Echinococcus granulosus CAAX prenyl protease 2 0.0187 0.1477 0.3003
Trypanosoma cruzi metallo- peptidase, Clan MG, Family M24 0.0074 0.0519 0.1051
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.005 0.0315 0.0637
Mycobacterium ulcerans Type I modular polyketide synthase 0.005 0.0322 0.1149
Loa Loa (eye worm) hypothetical protein 0.0036 0.0198 0.0223
Trypanosoma cruzi AMP deaminase, putative 0.0112 0.0843 0.1711
Schistosoma mansoni chromobox protein 0.0073 0.0509 0.1032
Schistosoma mansoni hypothetical protein 0.0124 0.0942 0.1913
Loa Loa (eye worm) hypothetical protein 0.0232 0.1856 0.2112
Echinococcus granulosus neuropeptides capa receptor 0.0036 0.0198 0.0398
Echinococcus multilocularis methionyl aminopeptidase 2 0.0594 0.4913 0.6981
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.005 0.0315 0.0637
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0014 0.001 0.0015
Loa Loa (eye worm) hypothetical protein 0.0036 0.0198 0.0223
Loa Loa (eye worm) hypothetical protein 0.0036 0.0198 0.0223
Echinococcus granulosus dro:myosuppressin receptor 0.0036 0.0198 0.0398
Loa Loa (eye worm) hypothetical protein 0.0036 0.0198 0.0223
Loa Loa (eye worm) hypothetical protein 0.0036 0.0198 0.0223
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0003 0.0001
Schistosoma mansoni neuropeptide receptor 0.0036 0.0198 0.0398
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.002 0.0065 0.0126
Trichomonas vaginalis sucrase-isomaltase, putative 0.0036 0.0203 0.0193
Loa Loa (eye worm) hypothetical protein 0.002 0.0065 0.007
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.0054 0.0349 0.1243
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0036 0.0198 0.0398
Toxoplasma gondii beta-ketoacyl synthase, N-terminal domain-containing protein 0.0033 0.0172 0.0345
Echinococcus granulosus jumonji domain containing protein 0.0041 0.0239 0.048
Echinococcus multilocularis G protein coupled receptor 139 0.0036 0.0198 0.0278
Onchocerca volvulus 0.0036 0.0198 0.0198
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0105 0.0207
Echinococcus granulosus survival motor neuron protein 1 0.0238 0.1906 0.3877
Plasmodium falciparum methionine aminopeptidase 1c, putative 0.0074 0.0519 0.1051
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0118 0.0132
Loa Loa (eye worm) hypothetical protein 0.0238 0.1906 0.217
Trichomonas vaginalis chromobox protein, putative 0.0044 0.0266 0.0256
Schistosoma mansoni ran 0.0021 0.0075 0.0147
Echinococcus multilocularis xaa Pro dipeptidase 0.0074 0.0519 0.0733
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.002 0.0065 0.0126
Loa Loa (eye worm) neuropeptide F receptor 0.0036 0.0198 0.0223
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0329 0.0319
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0025 0.0105 0.0373
Plasmodium vivax methionine aminopeptidase 1b, putative 0.0074 0.0519 0.1051
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1051 0.8774 1
Brugia malayi neuropeptide F receptor 0.0036 0.0198 0.0226
Echinococcus multilocularis Xaa Pro aminopeptidase 3 0.0074 0.0519 0.0733
Schistosoma mansoni family U48 unassigned peptidase (U48 family) 0.0187 0.1477 0.3003
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.0087 0.0629 0.0891
Mycobacterium ulcerans dipeptidase 0.0074 0.0519 0.185
Giardia lamblia PHD finger protein 15 0.0029 0.0142 0.0241
Trypanosoma cruzi AMP deaminase 2, putative 0.0112 0.0843 0.1711
Schistosoma mansoni jumonji domain containing protein 0.0076 0.0537 0.1088
Trypanosoma cruzi ISWI complex protein 0.0015 0.0025 0.0045
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0132 0.1015 0.2062
Echinococcus multilocularis lysosomal alpha glucosidase 0.0164 0.1281 0.1817
Loa Loa (eye worm) hypothetical protein 0.0036 0.0198 0.0223
Brugia malayi Glycosyl hydrolases family 31 protein 0.0164 0.1281 0.146
Brugia malayi G-protein coupled receptor 0.0036 0.0198 0.0226
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0074 0.0519 0.0509
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.0022 0.0011
Loa Loa (eye worm) hypothetical protein 0.0036 0.0198 0.0223
Brugia malayi hypothetical protein 0.0452 0.3715 0.4234
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.0329 0.0664
Echinococcus multilocularis Protein lozenge 0.0057 0.0375 0.0529
Echinococcus multilocularis serotonin receptor 0.0036 0.0198 0.0278
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0036 0.02 0.028
Schistosoma mansoni neuropeptide F-like receptor 0.0036 0.0198 0.0398
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0096 0.0703 0.1426
Trypanosoma brucei glyceraldehyde-3-phosphate dehydrogenase, putative 0.0087 0.0629 0.1275
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0132 0.1015 0.1006
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0036 0.0198 0.0223
Leishmania major methionine aminopeptidase, putative,metallo-peptidase, Clan MG, Family M24 0.0074 0.0519 0.1051
Plasmodium vivax methionine aminopeptidase 1a, putative 0.0074 0.0519 0.1051
Onchocerca volvulus 0.0163 0.1274 0.1274
Echinococcus multilocularis thyroid hormone receptor alpha 0.002 0.0065 0.0088
Toxoplasma gondii histone lysine methyltransferase SET1 0.0062 0.0423 0.0855
Echinococcus granulosus cytidine deaminase 0.0052 0.0339 0.0684
Mycobacterium tuberculosis Probable fatty acid synthase Fas (fatty acid synthetase) 0.0016 0.003 0.0106
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0074 0.0519 0.0509
Echinococcus multilocularis tar DNA binding protein 0.0074 0.0523 0.074
Trichomonas vaginalis adenosylhomocysteinase, putative 0.0044 0.0266 0.0256
Echinococcus multilocularis GPCR, family 2 0.0124 0.0942 0.1336
Trypanosoma cruzi CAAX prenyl protease 2, putative 0.0187 0.1477 0.3003
Brugia malayi PHD-finger family protein 0.0027 0.012 0.0137
Echinococcus granulosus mitogen activated protein kinase 0.0051 0.0329 0.0664
Loa Loa (eye worm) hypothetical protein 0.002 0.0065 0.007
Schistosoma mansoni biogenic amine receptor 0.0036 0.0198 0.0398
Mycobacterium leprae Probable adenosine deaminase Add (ADENOSINE AMINOHYDROLASE) 0.0344 0.2802 1
Schistosoma mansoni hypothetical protein 0.0308 0.2497 0.5081
Loa Loa (eye worm) TAR-binding protein 0.0074 0.0523 0.0593
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0024 0.0014
Echinococcus multilocularis rhodopsin orphan GPCR 0.0036 0.0198 0.0278
Echinococcus granulosus xaa Pro dipeptidase 0.0074 0.0519 0.1051
Schistosoma mansoni neuropeptide F-like receptor 0.0036 0.0198 0.0398
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0036 0.0198 0.0278
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0594 0.4913 0.4907
Echinococcus multilocularis neuropeptide receptor 0.0036 0.0198 0.0278
Onchocerca volvulus 0.0036 0.0198 0.0198
Echinococcus multilocularis Proliferation associated protein 2G4 0.0074 0.0519 0.0733
Toxoplasma gondii hypothetical protein 0.0039 0.0222 0.0447
Loa Loa (eye worm) hypothetical protein 0.0036 0.0198 0.0223
Brugia malayi G-protein coupled receptor 0.0036 0.0198 0.0226
Echinococcus multilocularis rhodopsin orphan GPCR 0.0036 0.0198 0.0278
Echinococcus multilocularis fmrfamide receptor 0.0036 0.0198 0.0278
Brugia malayi hypothetical protein 0.0073 0.051 0.0581
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0015 0.0014
Loa Loa (eye worm) hypothetical protein 0.0036 0.0198 0.0223
Echinococcus multilocularis somatostatin receptor 0.0036 0.0198 0.0278
Mycobacterium leprae Probable glyceraldehyde 3-phosphate dehydrogenase Gap (GAPDH) 0.0046 0.0282 0.1007
Echinococcus granulosus tm gpcr rhodopsin 0.0036 0.0198 0.0398
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0036 0.0198 0.0398
Loa Loa (eye worm) hypothetical protein 0.0036 0.0198 0.0223
Schistosoma mansoni amine GPCR 0.0036 0.0198 0.0398
Loa Loa (eye worm) initiation factor 2-associated protein 0.0594 0.4913 0.5598
Loa Loa (eye worm) hypothetical protein 0.0018 0.0052 0.0056
Schistosoma mansoni ap endonuclease 0.0018 0.0051 0.0098
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0015 0.0026 0.0048
Loa Loa (eye worm) hypothetical protein 0.0074 0.0519 0.0588
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0015 0.0026 0.0015
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0093 0.0185
Echinococcus granulosus snurportin 1 0.0308 0.2497 0.5081
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0074 0.0519 0.0509
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0075 0.0147
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.0051 0.0098
Trypanosoma brucei cytidine deaminase 0.0052 0.0339 0.0684
Onchocerca volvulus 0.0036 0.0198 0.0198
Echinococcus granulosus alpha 1A adrenergic receptor 0.0036 0.0198 0.0398
Mycobacterium leprae PROBABLE FATTY ACID SYNTHASE FAS (FATTY ACID SYNTHETASE) 0.0016 0.003 0.0105
Echinococcus granulosus neuropeptide FF receptor 2 0.0036 0.0198 0.0398
Mycobacterium tuberculosis Polyketide synthase Pks12 0.0054 0.0349 0.1244
Loa Loa (eye worm) hypothetical protein 0.0029 0.0142 0.0159
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0145 0.1122 0.2279
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0036 0.0198 0.0398
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0036 0.02 0.0401
Echinococcus multilocularis lysosomal alpha glucosidase 0.0164 0.1281 0.1817
Loa Loa (eye worm) TYRA-2 protein 0.0036 0.0198 0.0223
Leishmania major importin beta-1 subunit, putative 0.0023 0.0093 0.0185
Schistosoma mansoni survival motor neuron protein 0.0049 0.0306 0.0617
Schistosoma mansoni biogenic amine receptor 0.0036 0.0198 0.0398
Echinococcus granulosus adenosine deaminase 0.0344 0.2802 0.5702
Schistosoma mansoni ran 0.0021 0.0075 0.0147
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.002 0.0065 0.0126
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0065 0.0088
Plasmodium vivax FACT complex subunit SPT16, putative 0.0074 0.0519 0.1051
Schistosoma mansoni biogenic amine (5HT) receptor 0.0036 0.0198 0.0398
Brugia malayi Steroid receptor seven-up type 2 0.002 0.0065 0.0073
Loa Loa (eye worm) hypothetical protein 0.0232 0.1856 0.2112
Echinococcus granulosus rhodopsin orphan GPCR 0.0036 0.0198 0.0398
Schistosoma mansoni RAR-like nuclear receptor 0.002 0.0065 0.0126
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0203 0.0193
Brugia malayi intermediate filament protein 0.0026 0.0118 0.0135
Loa Loa (eye worm) glyceraldehyde 3-phosphate dehydrogenase 0.0087 0.0629 0.0714
Toxoplasma gondii CAAX amino terminal protease family protein 0.0039 0.0222 0.0447
Treponema pallidum aminopeptidase P 0.0074 0.0519 0.17
Brugia malayi Glyceraldehyde 3-phosphate dehydrogenase 0.0046 0.0282 0.0321
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0075 0.0103
Echinococcus granulosus xaa pro aminopeptidase 0.0074 0.0519 0.1051
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0041 0.0243 0.0488
Plasmodium vivax methionine aminopeptidase 2, putative 0.0594 0.4913 1
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0075 0.0147
Schistosoma mansoni alpha glucosidase 0.0036 0.0203 0.0408
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0105 0.0119
Giardia lamblia Methionine aminopeptidase 0.0594 0.4913 1
Loa Loa (eye worm) hypothetical protein 0.0029 0.014 0.0156
Echinococcus granulosus lysine specific demethylase 5A 0.0039 0.0224 0.0451
Echinococcus granulosus lamin 0.0026 0.0118 0.0235
Brugia malayi Dopamine receptor protein 1 0.0036 0.0198 0.0226
Mycobacterium tuberculosis Probable polyketide synthase Pks9 0.0029 0.0138 0.0493
Loa Loa (eye worm) glyceraldehyde-3-phosphate dehydrogenase 0.0091 0.0668 0.0759
Loa Loa (eye worm) hypothetical protein 0.0018 0.0052 0.0056
Echinococcus multilocularis snurportin 1 0.0308 0.2497 0.3547
Brugia malayi hypothetical protein 0.0036 0.0198 0.0226
Brugia malayi Nuclear hormone receptor family member nhr-3 0.002 0.0065 0.0073
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.005 0.0315 0.1125
Trypanosoma brucei CAAX amino terminal protease, putative 0.0187 0.1477 0.3003
Brugia malayi Nuclear hormone receptor family member nhr-40 0.002 0.0065 0.0073
Entamoeba histolytica Ran family GTPase 0.0021 0.0075 0.0132
Onchocerca volvulus 0.0052 0.0339 0.0338
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0036 0.0198 0.0398
Echinococcus granulosus Xaa Pro aminopeptidase 3 0.0074 0.0519 0.1051
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0124 0.0942 0.1074
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.004 0.0076
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0163 0.1274 0.2589
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0138 0.1066 0.2165
Echinococcus multilocularis citrate lyase subunit beta protein 0.005 0.0315 0.0444
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0142 0.0159
Echinococcus multilocularis adenosine deaminase 0.0344 0.2802 0.398
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0014 0.001 0.001
Onchocerca volvulus 0.0095 0.0699 0.0699
Loa Loa (eye worm) hypothetical protein 0.0074 0.0519 0.0588
Entamoeba histolytica cytidine deaminase, putative 0.0052 0.0339 0.067
Loa Loa (eye worm) G-protein coupled receptor 0.0036 0.0198 0.0223
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0012 0 0.0001
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0142 0.0284
Brugia malayi hypothetical protein 0.0036 0.0198 0.0226
Plasmodium falciparum phd finger protein, putative 0.0029 0.0142 0.0284
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.0132 0.1015 0.205
Brugia malayi Dopamine receptor protein 2 0.0036 0.0198 0.0226
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.005 0.0315 0.0637
Loa Loa (eye worm) hypothetical protein 0.0036 0.0198 0.0223
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.0004
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0051 0.0041
Mycobacterium leprae Probable cytoplasmic peptidase PepQ 0.0074 0.0519 0.185
Mycobacterium ulcerans aminopeptidase 0.0074 0.0519 0.185
Echinococcus granulosus orexin receptor type 2 0.0036 0.0198 0.0398
Giardia lamblia Xaa-Pro dipeptidase 0.0074 0.0519 0.1011
Echinococcus granulosus FACT complex subunit SPT16 0.0074 0.0519 0.1051
Trypanosoma cruzi hypothetical protein, conserved 0.0431 0.3539 0.7202
Brugia malayi RNA binding protein 0.0074 0.0523 0.0596
Onchocerca volvulus 0.0036 0.0198 0.0198
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0105 0.0373
Entamoeba histolytica adenosine deaminase, putative 0.0344 0.2802 0.5696
Mycobacterium tuberculosis Conserved hypothetical protein 0.0039 0.0222 0.0793
Mycobacterium ulcerans hypothetical protein 0.005 0.0315 0.1125
Echinococcus multilocularis lamin 0.0026 0.0118 0.0164
Brugia malayi sulfakinin receptor protein 0.0036 0.0198 0.0226
Loa Loa (eye worm) hypothetical protein 0.0036 0.0198 0.0223
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.0132 0.1015 0.205
Echinococcus granulosus ecdysone induced protein 78C 0.002 0.0065 0.0126
Plasmodium vivax importin-beta 2, putative 0.0029 0.014 0.0278
Chlamydia trachomatis methionine aminopeptidase 0.0074 0.0519 0.5095
Echinococcus multilocularis neuropeptides capa receptor 0.0036 0.0198 0.0278
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0096 0.0703 0.0995
Mycobacterium ulcerans thioesterase TesA 0.0042 0.0251 0.0895
Schistosoma mansoni blooms syndrome DNA helicase 0.0016 0.0035 0.0065
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0025 0.0105 0.0373
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0139 0.0155
Echinococcus multilocularis xaa Pro dipeptidase 0.0074 0.0519 0.0733
Plasmodium falciparum proliferation-associated protein 2g4, putative 0.0074 0.0519 0.1051
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0105 0.0373
Onchocerca volvulus 0.0049 0.0306 0.0306
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0132 0.1015 0.2062
Schistosoma mansoni aminopeptidase P1 (M24 family) 0.0074 0.0519 0.1051
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0036 0.0198 0.0226
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0065 0.0073
Echinococcus multilocularis methionine aminopeptidase, type I 0.0074 0.0519 0.0733
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.005 0.0322 0.115
Echinococcus granulosus serotonin receptor 0.0036 0.0198 0.0398
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0142 0.0284
Schistosoma mansoni zinc finger protein 0.0021 0.0075 0.0147
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0065 0.0126
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0015 0.0026 0.0048
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0845 0.7036 1
Mycobacterium tuberculosis Probable glyceraldehyde 3-phosphate dehydrogenase Gap (GAPDH) 0.0046 0.0282 0.1008
Loa Loa (eye worm) DNA-binding protein 0.0074 0.0519 0.0588
Echinococcus granulosus biogenic amine 5HT receptor 0.0036 0.0198 0.0398
Loa Loa (eye worm) bromodomain containing protein 0.0018 0.0045 0.0048
Plasmodium vivax adenosine deaminase, putative 0.0344 0.2802 0.5702
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0203 0.0193
Brugia malayi Importin beta-1 subunit 0.0029 0.014 0.0159
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0304 0.0613
Schistosoma mansoni neuropeptide receptor 0.0036 0.0198 0.0398
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0075 0.0147
Schistosoma mansoni retinoic acid receptor RXR 0.002 0.0065 0.0126
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0138 0.1066 0.1214
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.005 0.0322 0.1149
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0132 0.1015 0.2062
Trypanosoma cruzi cytidine deaminase-like protein 0.0052 0.0339 0.0684
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0036 0.0198 0.0398
Loa Loa (eye worm) RNA binding protein 0.0074 0.0523 0.0593
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0036 0.0198 0.0398
Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase, putative 0.0087 0.0629 0.1275
Echinococcus granulosus dnaJ subfamily B 0.0409 0.3353 0.6823
Loa Loa (eye worm) adenosylhomocysteinase 0.014 0.1075 0.1222
Echinococcus multilocularis neuropeptide FF receptor 2 0.0036 0.0198 0.0278
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0061 0.0414 0.0838
Brugia malayi F/Y-rich N-terminus family protein 0.0026 0.0113 0.0129
Mycobacterium tuberculosis Polyketide synthetase MbtD (polyketide synthase) 0.0016 0.0027 0.0096
Entamoeba histolytica hypothetical protein 0.0073 0.051 0.102
Leishmania major hypothetical protein, conserved 0.0015 0.0025 0.0045
Schistosoma mansoni hypothetical protein 0.0036 0.0198 0.0398
Echinococcus granulosus citrate lyase subunit beta protein 0.005 0.0315 0.0637
Echinococcus granulosus neuropeptide receptor A26 0.0505 0.4166 0.8479
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0018 0.0051 0.0055
Brugia malayi hypothetical protein 0.0036 0.0198 0.0226
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0027 0.012 0.0238
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0036 0.0198 0.0278
Trichomonas vaginalis adenosylhomocysteinase, putative 0.014 0.1075 0.1065
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0124 0.0942 0.1913
Trypanosoma cruzi ISWI complex protein 0.0015 0.0025 0.0045
Brugia malayi metallopeptidase family M24 containing protein 0.0074 0.0519 0.0591
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE 0.0033 0.0178 0.0634
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0018 0.0051 0.0098
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0015 0.0026 0.0033
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MG, Family M24 0.0074 0.0519 0.1051
Echinococcus granulosus lysosomal alpha glucosidase 0.0164 0.1281 0.2603
Brugia malayi CAAX amino terminal protease family protein 0.0187 0.1477 0.1683
Loa Loa (eye worm) hypothetical protein 0.0036 0.0198 0.0223
Toxoplasma gondii transcriptional elongation factor FACT140 0.0074 0.0519 0.1051
Loa Loa (eye worm) hypothetical protein 0.0036 0.0198 0.0223
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0139 0.0129
Schistosoma mansoni hypothetical protein 0.0029 0.0142 0.0284
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0138 0.1066 0.2165
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0065 0.0126
Brugia malayi hypothetical protein 0.0238 0.1906 0.2172
Schistosoma mansoni tar DNA-binding protein 0.0074 0.0523 0.106
Echinococcus granulosus Proliferation associated protein 2G4 0.0074 0.0519 0.1051
Leishmania major hypothetical protein, conserved 0.0431 0.3539 0.7202
Trypanosoma cruzi metallo-peptidase, Clan MG, Family M24, putative 0.0074 0.0519 0.1051
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0151 0.1174 0.1665
Loa Loa (eye worm) hypothetical protein 0.002 0.0065 0.007
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0132 0.1015 0.2062
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.0132 0.1015 0.2062
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0132 0.1015 0.1006
Echinococcus granulosus g protein coupled receptor 0.0036 0.0198 0.0398
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.0051 0.0068
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.002 0.0065 0.0064
Echinococcus granulosus g protein coupled receptor 0.0036 0.0198 0.0398
Onchocerca volvulus 0.0026 0.0118 0.0118
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0024 0.01 0.0198
Plasmodium vivax glyceraldehyde-3-phosphate dehydrogenase, putative 0.0132 0.1015 0.2062
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0065 0.0073
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0065 0.0073
Loa Loa (eye worm) hypothetical protein 0.0036 0.0198 0.0223
Mycobacterium ulcerans polyketide synthase 0.0054 0.0349 0.1243
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0018 0.0051 0.0181
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0018 0.0051 0.0083
Loa Loa (eye worm) G-protein coupled receptor 0.0036 0.0198 0.0223
Brugia malayi Glyceraldehyde 3-phosphate dehydrogenase 0.0132 0.1015 0.1157
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0087 0.0629 0.062
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0022 0.0083 0.0164
Trypanosoma cruzi aminopeptidase P, putative 0.0074 0.0519 0.1051
Loa Loa (eye worm) hypothetical protein 0.0036 0.0198 0.0223
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.0072 0.0062
Schistosoma mansoni adenoreceptor 0.0036 0.0198 0.0398
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0013 0.0005 0.0005
Mycobacterium ulcerans hypothetical protein 0.005 0.0315 0.1125
Loa Loa (eye worm) hypothetical protein 0.0044 0.027 0.0305
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0051 0.0329 0.0664
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0036 0.0198 0.0226
Schistosoma mansoni hypothetical protein 0.0073 0.051 0.1033
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0054 0.0355 0.1268
Plasmodium vivax acyl-CoA synthetase, putative 0.0018 0.0052 0.01
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.0132 0.1015 0.1439
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0041 0.0243 0.0488
Mycobacterium tuberculosis Conserved protein 0.005 0.0315 0.1125
Schistosoma mansoni nuclear hormone receptor 0.002 0.0065 0.0126
Echinococcus multilocularis ecdysone induced protein 78C 0.002 0.0065 0.0088
Echinococcus multilocularis cpg binding protein 0.0032 0.0169 0.0236
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0203 0.0393
Leishmania major AMP deaminase, putative 0.0112 0.0843 0.1711
Echinococcus multilocularis rhodopsin orphan GPCR 0.0036 0.0198 0.0278
Echinococcus granulosus histone lysine methyltransferase setb 0.0168 0.1318 0.2679
Mycobacterium leprae putative S-adenosyl-L-homocysteine hydrolase SahH 0.014 0.1075 0.3834
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0014 0.0013 0.0022
Toxoplasma gondii cytidine and deoxycytidylate deaminase zinc-binding region domain-containing protein 0.0052 0.0339 0.0684
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0075 0.0104
Echinococcus granulosus neuropeptide receptor 0.0036 0.0198 0.0398
Brugia malayi Serotonin receptor 0.0036 0.0198 0.0226
Loa Loa (eye worm) hypothetical protein 0.0036 0.0198 0.0223
Giardia lamblia Glyceraldehyde 3-phosphate dehydrogenase 0.0087 0.0629 0.1236
Mycobacterium tuberculosis Probable conserved integral membrane protein 0.0039 0.0222 0.0793
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0074 0.0519 0.0509
Loa Loa (eye worm) hypothetical protein 0.0025 0.0105 0.0116
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0018 0.0052 0.0484
Onchocerca volvulus 0.0052 0.0339 0.0338
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0074 0.0519 0.0509
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0142 0.0284
Echinococcus multilocularis neuropeptide Y receptor 0.0036 0.0198 0.0278
Mycobacterium ulcerans integral membrane protein 0.0039 0.0222 0.0792
Loa Loa (eye worm) CHromoDomain protein family member 0.0015 0.0026 0.0027
Trypanosoma cruzi AMP deaminase, putative 0.0112 0.0843 0.1711
Trichomonas vaginalis adenosine deaminase, putative 0.0344 0.2802 0.2795
Echinococcus multilocularis sex peptide receptor 0.0036 0.0198 0.0278
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0072 0.0062
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0051 0.0041
Loa Loa (eye worm) hypothetical protein 0.0025 0.0105 0.0116
Echinococcus multilocularis g protein coupled receptor 0.0036 0.0198 0.0278
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.0105 0.0373
Brugia malayi Heterochromatin protein 1 0.0073 0.0509 0.058
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0132 0.1015 0.1006
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.005 0.0315 0.1125
Loa Loa (eye worm) hypothetical protein 0.0124 0.0942 0.1071
Wolbachia endosymbiont of Brugia malayi methionine aminopeptidase 0.0074 0.0519 0.5095
Brugia malayi jmjC domain containing protein 0.0096 0.0703 0.0801
Onchocerca volvulus 0.0036 0.0198 0.0198
Loa Loa (eye worm) hypothetical protein 0.0036 0.0198 0.0223
Loa Loa (eye worm) AMP deaminase 0.0112 0.0843 0.0958
Schistosoma mansoni methionyl aminopeptidase 1 (M24 family) 0.0074 0.0519 0.1051
Loa Loa (eye worm) hypothetical protein 0.0036 0.0198 0.0223
Mycobacterium tuberculosis Probable polyketide synthase Pks1 0.0036 0.0202 0.0721
Schistosoma mansoni tar DNA-binding protein 0.0074 0.0523 0.106
Brugia malayi Nuclear hormone receptor family member nhr-31 0.002 0.0065 0.0073
Loa Loa (eye worm) hypothetical protein 0.002 0.0065 0.007
Entamoeba histolytica hypothetical protein 0.0073 0.051 0.102
Schistosoma mansoni adenosylhomocysteinase 0.014 0.1075 0.2183
Echinococcus multilocularis bloom syndrome protein 0.0021 0.0072 0.0098
Onchocerca volvulus 0.002 0.0065 0.0064
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.0329 0.0664
Plasmodium vivax protease, putative 0.0039 0.0222 0.0447
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0036 0.0198 0.0226
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0168 0.1318 0.2679
Loa Loa (eye worm) melatonin receptor type 1A 0.0036 0.0198 0.0223
Brugia malayi Glycosyl hydrolases family 31 protein 0.0036 0.0203 0.0231
Trypanosoma cruzi metallo-peptidase, Clan MG, Family M24 0.0074 0.0519 0.1051
Schistosoma mansoni histamine h1 receptor 0.0036 0.0198 0.0398
Echinococcus multilocularis cytidine deaminase 0.0052 0.0339 0.0477
Echinococcus granulosus importin subunit beta 1 0.0029 0.014 0.0278
Echinococcus granulosus peregrin 0.0032 0.0162 0.0325
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0012 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0253 0.2031 0.2312
Brugia malayi adenosine monophosphate deaminase 0.0112 0.0843 0.096
Echinococcus multilocularis neuropeptide receptor 0.0036 0.0198 0.0278
Plasmodium falciparum adenosine deaminase 0.0344 0.2802 0.5702
Leishmania major adenine aminohydrolase 0.0344 0.2802 0.5702
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0065 0.0073
Echinococcus multilocularis rhodopsin orphan GPCR 0.0036 0.0198 0.0278
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0065 0.0073
Onchocerca volvulus 0.0036 0.0198 0.0198
Plasmodium falciparum FACT complex subunit SPT16, putative 0.0074 0.0519 0.1051
Mycobacterium leprae PROBABLE METHIONINE AMINOPEPTIDASE MAPA (MAP) (PEPTIDASE M) (MetAP) 0.0074 0.0519 0.185
Trypanosoma brucei protein kinase, putative 0.0051 0.0329 0.0664
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0036 0.0198 0.0398
Trypanosoma cruzi metallo-peptidase, Clan MG, Family M24 0.0594 0.4913 1
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.0042 0.0251 0.0895
Loa Loa (eye worm) MH2 domain-containing protein 0.0134 0.1029 0.117
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0014 0.0018 0.0021
Mycobacterium ulcerans hypothetical protein 0.0025 0.0105 0.0373
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0052 0.0185
Brugia malayi DNA-binding protein, 42 kDa containing protein 0.0074 0.0519 0.0591
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.0132 0.1015 0.205
Trichomonas vaginalis chromobox protein, putative 0.0073 0.0509 0.05
Toxoplasma gondii S-Adenosyl homocysteine hydrolase 0.014 0.1075 0.2183
Schistosoma mansoni hypothetical protein 0.0177 0.1388 0.2821
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.002 0.0065 0.0088
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0025 0.0105 0.0373
Mycobacterium ulcerans polyketide synthase Pks9 0.0033 0.0178 0.0634
Echinococcus granulosus cpg binding protein 0.0032 0.0169 0.0337
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0065 0.0126
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0025 0.0105 0.0373
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0066 0.0458 0.0926
Brugia malayi Nuclear hormone receptor family member nhr-1 0.002 0.0065 0.0073
Brugia malayi nuclear receptor NHR-88 0.002 0.0065 0.0073
Echinococcus granulosus fetal alzheimer antigen falz 0.0024 0.01 0.0198
Schistosoma mansoni lamin 0.0026 0.0118 0.0235
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.002 0.0065 0.0126
Plasmodium falciparum acyl-CoA synthetase 0.0018 0.0052 0.01
Mycobacterium ulcerans Type I modular polyketide synthase 0.005 0.0322 0.1149
Echinococcus granulosus methionyl aminopeptidase 1 M24 family 0.0074 0.0519 0.1051
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.024 0.023
Onchocerca volvulus 0.0036 0.0198 0.0198
Schistosoma mansoni hypothetical protein 0.0124 0.0942 0.1913
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0551 0.4553 0.5189
Loa Loa (eye worm) jmjC domain-containing protein 0.006 0.0405 0.0458
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.0041 0.0244 0.0872
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.0142 0.0284
Leishmania major hypothetical protein, conserved 0.0112 0.0843 0.1711
Schistosoma mansoni hypothetical protein 0.0036 0.0198 0.0398
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0138 0.1066 0.1212
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0036 0.0198 0.0398
Schistosoma mansoni coup transcription factor 0.002 0.0065 0.0126
Schistosoma mansoni chromatin-specific transcription elongation factor 140 kDa subunit (M24 family) 0.0074 0.0519 0.1051
Echinococcus multilocularis dro:myosuppressin receptor 0.0036 0.0198 0.0278
Loa Loa (eye worm) hypothetical protein 0.0036 0.0198 0.0223
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0036 0.0198 0.0278
Trypanosoma cruzi aminopeptidase P1, putative 0.0074 0.0519 0.1051
Loa Loa (eye worm) hypothetical protein 0.002 0.0065 0.007
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0041 0.0239 0.0852
Onchocerca volvulus 0.0036 0.0198 0.0198
Mycobacterium ulcerans methionine aminopeptidase 0.0074 0.0519 0.185
Trypanosoma cruzi adenosine monophosphate deaminase-like protein, putative 0.0112 0.0843 0.1711
Plasmodium falciparum methionine aminopeptidase 2 0.0594 0.4913 1
Brugia malayi hypothetical protein 0.0036 0.0198 0.0226
Brugia malayi Calcitonin receptor-like protein seb-1 0.0391 0.3203 0.365
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0036 0.0198 0.0226
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.005 0.0322 0.115
Schistosoma mansoni ap endonuclease 0.0018 0.0051 0.0098
Loa Loa (eye worm) hypothetical protein 0.0036 0.0198 0.0223
Brugia malayi Bromodomain containing protein 0.0077 0.0544 0.0619
Echinococcus granulosus biogenic amine 5HT receptor 0.0036 0.0198 0.0398
Mycobacterium ulcerans thioesterase 0.0042 0.0251 0.0895
Trypanosoma brucei metallo- peptidase, Clan MG, Family M24 0.0074 0.0519 0.1051
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0065 0.0073
Brugia malayi hypothetical protein 0.0036 0.0198 0.0226
Treponema pallidum hypothetical protein 0.0039 0.0222 0.0622
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0036 0.0198 0.0398
Schistosoma mansoni amine GPCR 0.0036 0.0198 0.0398
Entamoeba histolytica peptidase, putative 0.0074 0.0519 0.1037
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0043 0.0155
Entamoeba histolytica adenosine deaminase, putative 0.0344 0.2802 0.5696
Echinococcus multilocularis AMP deaminase 2 0.0112 0.0843 0.1194
Onchocerca volvulus 0.0036 0.0198 0.0198
Leishmania major aminopeptidase P1, putative,metallo-peptidase, Clan MG, Family M24 0.0074 0.0519 0.1051
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0036 0.0198 0.0398
Onchocerca volvulus Neuropeptide F receptor homolog 0.0036 0.0198 0.0198
Echinococcus granulosus bloom syndrome protein 0.0021 0.0072 0.0141
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0036 0.0198 0.0278
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0051 0.0041
Loa Loa (eye worm) hypothetical protein 0.0038 0.022 0.0248
Loa Loa (eye worm) hypothetical protein 0.0036 0.0198 0.0223
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0043 0.0155
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.002 0.0065 0.0126
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0118 0.0132
Brugia malayi steroid hormone receptor 0.002 0.0065 0.0073
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.0054 0.0349 0.1244
Toxoplasma gondii adenosylhomocysteinase, putative 0.014 0.1075 0.2183
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0203 0.0193
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.002 0.0065 0.007
Mycobacterium leprae Polyketide synthase Pks13 0.0075 0.0533 0.1901
Echinococcus granulosus chromobox protein 1 0.0073 0.0509 0.1032
Entamoeba histolytica AMP deaminase, putative 0.0112 0.0843 0.1698
Brugia malayi follicle stimulating hormone receptor 0.0036 0.0198 0.0226
Entamoeba histolytica AMP deaminase, putative 0.0112 0.0843 0.1698
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0036 0.0203 0.0228
Loa Loa (eye worm) hypothetical protein 0.0036 0.0198 0.0223

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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