Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | cysteine protease, putative | 0.0081 | 0.1472 | 1 |
Leishmania major | cathepsin L-like protease | 0.0294 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0081 | 0.1472 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0081 | 0.1472 | 0.2895 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0081 | 0.1472 | 1 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0081 | 0.1472 | 0.2895 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0294 | 1 | 1 |
Plasmodium vivax | vivapain-2 | 0.0081 | 0.1472 | 1 |
Leishmania major | cathepsin L-like protease | 0.0081 | 0.1472 | 0.0649 |
Brugia malayi | Cathepsin L-like precursor | 0.0081 | 0.1472 | 0.2895 |
Echinococcus multilocularis | cysteine protease | 0.0081 | 0.1472 | 0.2895 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.1472 | 0.2174 |
Echinococcus multilocularis | cysteine protease | 0.0081 | 0.1472 | 0.2895 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0081 | 0.1472 | 0.2895 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0081 | 0.1472 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0056 | 0.0468 | 0.0921 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0081 | 0.1472 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0081 | 0.1472 | 0.2895 |
Leishmania major | cathepsin L-like protease | 0.0081 | 0.1472 | 0.0649 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0081 | 0.1472 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0081 | 0.1472 | 1 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0066 | 0.0879 | 0.0879 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0294 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0294 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0081 | 0.1472 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0081 | 0.1472 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0081 | 0.1472 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0081 | 0.1472 | 0.1472 |
Onchocerca volvulus | Cathepsin F homolog | 0.0081 | 0.1472 | 1 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0081 | 0.1472 | 0.2174 |
Loa Loa (eye worm) | hypothetical protein | 0.0171 | 0.5084 | 1 |
Onchocerca volvulus | 0.0081 | 0.1472 | 1 | |
Leishmania major | cysteine peptidase A (CPA) | 0.0081 | 0.1472 | 0.0649 |
Onchocerca volvulus | 0.0081 | 0.1472 | 1 | |
Onchocerca volvulus | 0.0081 | 0.1472 | 1 | |
Entamoeba histolytica | cysteine proteinase, putative | 0.0081 | 0.1472 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0081 | 0.1472 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0171 | 0.5084 | 1 |
Plasmodium vivax | vivapain-2 | 0.0081 | 0.1472 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0056 | 0.0468 | 0.3182 |
Echinococcus granulosus | cathepsin b | 0.0171 | 0.5084 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0081 | 0.1472 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0066 | 0.0879 | 0.5975 |
Onchocerca volvulus | 0.0081 | 0.1472 | 1 | |
Loa Loa (eye worm) | fibroinase | 0.0081 | 0.1472 | 0.2174 |
Giardia lamblia | Cathepsin B precursor | 0.0066 | 0.0879 | 0.5 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0171 | 0.5084 | 1 |
Leishmania major | cathepsin L-like protease | 0.0081 | 0.1472 | 0.0649 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0081 | 0.1472 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0081 | 0.1472 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0081 | 0.1472 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0081 | 0.1472 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0081 | 0.1472 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0056 | 0.0468 | 0.0921 |
Toxoplasma gondii | cathepsin CPL | 0.0081 | 0.1472 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0081 | 0.1472 | 0.2895 |
Leishmania major | cathepsin L-like protease | 0.0081 | 0.1472 | 0.0649 |
Brugia malayi | cathepsin L-like precursor | 0.0056 | 0.0468 | 0.0921 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0056 | 0.0468 | 0.3182 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0081 | 0.1472 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0081 | 0.1472 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0294 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0294 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0294 | 1 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0081 | 0.1472 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0081 | 0.1472 | 1 |
Loa Loa (eye worm) | cathepsin B | 0.0066 | 0.0879 | 0.0891 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0081 | 0.1472 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0081 | 0.1472 | 0.2895 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0171 | 0.5084 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0294 | 1 | 1 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0056 | 0.0468 | 0.0921 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0294 | 1 | 1 |
Echinococcus granulosus | cathepsin b | 0.0171 | 0.5084 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0081 | 0.1472 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0294 | 1 | 1 |
Echinococcus multilocularis | cathepsin b | 0.0171 | 0.5084 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0081 | 0.1472 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0081 | 0.1472 | 0.2895 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0081 | 0.1472 | 0.2895 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0171 | 0.5084 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0081 | 0.1472 | 0.2895 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0294 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0294 | 1 | 1 |
Loa Loa (eye worm) | cysteine protease | 0.0081 | 0.1472 | 0.2174 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0081 | 0.1472 | 1 |
Brugia malayi | cathepsin B-like cysteine proteinase | 0.0171 | 0.5084 | 1 |
Onchocerca volvulus | 0.0081 | 0.1472 | 1 | |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0081 | 0.1472 | 0.2895 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0081 | 0.1472 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0056 | 0.0468 | 0.0921 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0171 | 0.5084 | 0.5084 |
Brugia malayi | Cathepsin L-like precursor | 0.0081 | 0.1472 | 0.2895 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0081 | 0.1472 | 0.2174 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0294 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0081 | 0.1472 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0056 | 0.0468 | 0.3182 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0066 | 0.0879 | 0.0879 |
Brugia malayi | Cathepsin L-like precursor | 0.0081 | 0.1472 | 0.2895 |
Giardia lamblia | Cathepsin B precursor | 0.0066 | 0.0879 | 0.5 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0269 | 0.8997 | 0.8997 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0294 | 1 | 1 |
Echinococcus multilocularis | cathepsin b | 0.0171 | 0.5084 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0081 | 0.1472 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0081 | 0.1472 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0294 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0294 | 1 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0081 | 0.1472 | 0.2895 |
Onchocerca volvulus | Cathepsin L homolog | 0.0081 | 0.1472 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0056 | 0.0468 | 0.0921 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0294 | 1 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0066 | 0.0879 | 0.5 |
Loa Loa (eye worm) | ctsf protein | 0.0081 | 0.1472 | 0.2174 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0081 | 0.1472 | 1 |
Onchocerca volvulus | 0.0081 | 0.1472 | 1 | |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0232 | 0.7525 | 0.7525 |
Echinococcus granulosus | cathepsin l1 | 0.0081 | 0.1472 | 0.2895 |
Brugia malayi | Cathepsin L-like precursor | 0.0081 | 0.1472 | 0.2895 |
Leishmania major | cathepsin L-like protease | 0.0081 | 0.1472 | 0.0649 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0081 | 0.1472 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0066 | 0.0879 | 0.173 |
Onchocerca volvulus | 0.0081 | 0.1472 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.