Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.045 | 0.457 | 0.5208 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.045 | 0.457 | 0.457 |
Entamoeba histolytica | SH2-protein kinase domain containing protein | 0.0028 | 0 | 0.5 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0052 | 0.0259 | 0.0295 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0052 | 0.0259 | 0.0259 |
Loa Loa (eye worm) | hypothetical protein | 0.045 | 0.457 | 0.5208 |
Echinococcus multilocularis | g protein coupled receptor | 0.045 | 0.457 | 0.457 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0259 | 0.0295 |
Schistosoma mansoni | nuclear hormone receptor | 0.0052 | 0.0259 | 0.0259 |
Brugia malayi | GnHR receptor homolog | 0.045 | 0.457 | 0.5208 |
Schistosoma mansoni | neuropeptide receptor | 0.045 | 0.457 | 0.457 |
Schistosoma mansoni | biogenic amine receptor | 0.045 | 0.457 | 0.457 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0052 | 0.0259 | 0.0295 |
Echinococcus multilocularis | neuropeptide s receptor | 0.045 | 0.457 | 0.457 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0259 | 0.0295 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.045 | 0.457 | 0.5208 |
Echinococcus multilocularis | allatostatin A receptor | 0.045 | 0.457 | 0.457 |
Onchocerca volvulus | 0.045 | 0.457 | 0.5208 | |
Echinococcus granulosus | hypothetical protein | 0.045 | 0.457 | 0.457 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0052 | 0.0259 | 0.0295 |
Brugia malayi | hypothetical protein | 0.045 | 0.457 | 0.5208 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.045 | 0.457 | 0.457 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0052 | 0.0259 | 0.0259 |
Echinococcus granulosus | neuropeptide Y receptor | 0.045 | 0.457 | 0.457 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0052 | 0.0259 | 0.0295 |
Schistosoma mansoni | thyroid hormone receptor | 0.0052 | 0.0259 | 0.0259 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.045 | 0.457 | 0.457 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.045 | 0.457 | 0.457 |
Echinococcus multilocularis | tyrosine protein kinase shark | 0.0951 | 1 | 1 |
Brugia malayi | Melatonin receptor type 1A | 0.045 | 0.457 | 0.5208 |
Loa Loa (eye worm) | hypothetical protein | 0.045 | 0.457 | 0.5208 |
Echinococcus granulosus | g protein coupled receptor | 0.045 | 0.457 | 0.457 |
Schistosoma mansoni | hypothetical protein | 0.045 | 0.457 | 0.457 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.045 | 0.457 | 0.5208 |
Echinococcus multilocularis | orexin receptor type 2 | 0.045 | 0.457 | 0.457 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0052 | 0.0259 | 0.0295 |
Onchocerca volvulus | 0.045 | 0.457 | 0.5208 | |
Schistosoma mansoni | coup transcription factor | 0.0052 | 0.0259 | 0.0259 |
Onchocerca volvulus | 0.045 | 0.457 | 0.5208 | |
Onchocerca volvulus | 0.045 | 0.457 | 0.5208 | |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0052 | 0.0259 | 0.0295 |
Echinococcus multilocularis | serotonin receptor | 0.045 | 0.457 | 0.457 |
Onchocerca volvulus | 0.045 | 0.457 | 0.5208 | |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.045 | 0.457 | 0.457 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0052 | 0.0259 | 0.0295 |
Schistosoma mansoni | biogenic amine receptor | 0.045 | 0.457 | 0.457 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.045 | 0.457 | 0.457 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0052 | 0.0259 | 0.0295 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.045 | 0.457 | 0.457 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0052 | 0.0259 | 0.0295 |
Loa Loa (eye worm) | hypothetical protein | 0.045 | 0.457 | 0.5208 |
Brugia malayi | steroid hormone receptor | 0.0052 | 0.0259 | 0.0295 |
Schistosoma mansoni | amine GPCR | 0.045 | 0.457 | 0.457 |
Loa Loa (eye worm) | hypothetical protein | 0.045 | 0.457 | 0.5208 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.045 | 0.457 | 0.457 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.045 | 0.457 | 0.5208 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.045 | 0.457 | 0.457 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0052 | 0.0259 | 0.0295 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.045 | 0.457 | 0.457 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.045 | 0.457 | 0.457 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.045 | 0.457 | 0.5208 |
Brugia malayi | RE15519p | 0.045 | 0.457 | 0.5208 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.045 | 0.457 | 0.457 |
Brugia malayi | nuclear hormone receptor | 0.0052 | 0.0259 | 0.0295 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.045 | 0.457 | 0.457 |
Brugia malayi | neuropeptide F receptor | 0.045 | 0.457 | 0.5208 |
Loa Loa (eye worm) | hypothetical protein | 0.045 | 0.457 | 0.5208 |
Loa Loa (eye worm) | hypothetical protein | 0.045 | 0.457 | 0.5208 |
Schistosoma mansoni | amine GPCR | 0.045 | 0.457 | 0.457 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0052 | 0.0259 | 0.0259 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.045 | 0.457 | 0.457 |
Brugia malayi | Serotonin receptor | 0.045 | 0.457 | 0.5208 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0052 | 0.0259 | 0.0259 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0052 | 0.0259 | 0.0259 |
Loa Loa (eye worm) | hypothetical protein | 0.045 | 0.457 | 0.5208 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.045 | 0.457 | 0.457 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0052 | 0.0259 | 0.0295 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.045 | 0.457 | 0.457 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0259 | 0.0295 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0052 | 0.0259 | 0.0259 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0052 | 0.0259 | 0.0295 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.045 | 0.457 | 0.5208 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.045 | 0.457 | 0.457 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.045 | 0.457 | 0.457 |
Loa Loa (eye worm) | hypothetical protein | 0.045 | 0.457 | 0.5208 |
Schistosoma mansoni | myosin xvIII | 0.045 | 0.457 | 0.457 |
Brugia malayi | Serotonin receptor | 0.045 | 0.457 | 0.5208 |
Brugia malayi | ORL1-like opioid receptor | 0.045 | 0.457 | 0.5208 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.045 | 0.457 | 0.457 |
Loa Loa (eye worm) | hypothetical protein | 0.045 | 0.457 | 0.5208 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0052 | 0.0259 | 0.0259 |
Loa Loa (eye worm) | hypothetical protein | 0.045 | 0.457 | 0.5208 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.045 | 0.457 | 0.5208 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0052 | 0.0259 | 0.0259 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0052 | 0.0259 | 0.0259 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.045 | 0.457 | 0.5208 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0052 | 0.0259 | 0.0295 |
Loa Loa (eye worm) | hypothetical protein | 0.045 | 0.457 | 0.5208 |
Loa Loa (eye worm) | hypothetical protein | 0.045 | 0.457 | 0.5208 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.045 | 0.457 | 0.457 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.045 | 0.457 | 0.457 |
Echinococcus granulosus | neuropeptides capa receptor | 0.045 | 0.457 | 0.457 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.045 | 0.457 | 0.5208 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.045 | 0.457 | 0.457 |
Loa Loa (eye worm) | hypothetical protein | 0.045 | 0.457 | 0.5208 |
Echinococcus multilocularis | sex peptide receptor | 0.045 | 0.457 | 0.457 |
Loa Loa (eye worm) | hypothetical protein | 0.045 | 0.457 | 0.5208 |
Schistosoma mansoni | tyrosine kinase | 0.0929 | 0.9764 | 0.9764 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.045 | 0.457 | 0.457 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.045 | 0.457 | 0.457 |
Loa Loa (eye worm) | hypothetical protein | 0.045 | 0.457 | 0.5208 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.045 | 0.457 | 0.5208 |
Loa Loa (eye worm) | hypothetical protein | 0.045 | 0.457 | 0.5208 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0052 | 0.0259 | 0.0259 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.045 | 0.457 | 0.5208 |
Loa Loa (eye worm) | hypothetical protein | 0.045 | 0.457 | 0.5208 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0052 | 0.0259 | 0.0259 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0052 | 0.0259 | 0.0295 |
Echinococcus granulosus | neuropeptide receptor | 0.045 | 0.457 | 0.457 |
Loa Loa (eye worm) | hypothetical protein | 0.0838 | 0.8776 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.045 | 0.457 | 0.457 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.045 | 0.457 | 0.457 |
Loa Loa (eye worm) | hypothetical protein | 0.045 | 0.457 | 0.5208 |
Brugia malayi | hypothetical protein | 0.045 | 0.457 | 0.5208 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.045 | 0.457 | 0.457 |
Schistosoma mansoni | histamine h1 receptor | 0.045 | 0.457 | 0.457 |
Onchocerca volvulus | 0.045 | 0.457 | 0.5208 | |
Schistosoma mansoni | hypothetical protein | 0.045 | 0.457 | 0.457 |
Brugia malayi | hypothetical protein | 0.045 | 0.457 | 0.5208 |
Loa Loa (eye worm) | hypothetical protein | 0.045 | 0.457 | 0.5208 |
Loa Loa (eye worm) | hypothetical protein | 0.045 | 0.457 | 0.5208 |
Loa Loa (eye worm) | hypothetical protein | 0.045 | 0.457 | 0.5208 |
Schistosoma mansoni | hypothetical protein | 0.045 | 0.457 | 0.457 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.045 | 0.457 | 0.457 |
Brugia malayi | putative neuropeptide receptor | 0.045 | 0.457 | 0.5208 |
Loa Loa (eye worm) | hypothetical protein | 0.045 | 0.457 | 0.5208 |
Loa Loa (eye worm) | hypothetical protein | 0.045 | 0.457 | 0.5208 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0052 | 0.0259 | 0.0295 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0052 | 0.0259 | 0.0259 |
Echinococcus granulosus | fmrfamide receptor | 0.045 | 0.457 | 0.457 |
Onchocerca volvulus | 0.045 | 0.457 | 0.5208 | |
Schistosoma mansoni | adenoreceptor | 0.045 | 0.457 | 0.457 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.045 | 0.457 | 0.457 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.045 | 0.457 | 0.5208 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.045 | 0.457 | 0.457 |
Echinococcus granulosus | FTZ F1 alpha | 0.0052 | 0.0259 | 0.0259 |
Echinococcus granulosus | sex peptide receptor | 0.045 | 0.457 | 0.457 |
Brugia malayi | hypothetical protein | 0.045 | 0.457 | 0.5208 |
Brugia malayi | hypothetical protein | 0.045 | 0.457 | 0.5208 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.045 | 0.457 | 0.457 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.045 | 0.457 | 0.457 |
Loa Loa (eye worm) | hypothetical protein | 0.045 | 0.457 | 0.5208 |
Schistosoma mansoni | amine GPCR | 0.045 | 0.457 | 0.457 |
Loa Loa (eye worm) | hypothetical protein | 0.045 | 0.457 | 0.5208 |
Brugia malayi | Dopamine receptor | 0.045 | 0.457 | 0.5208 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.045 | 0.457 | 0.457 |
Echinococcus granulosus | g protein coupled receptor | 0.045 | 0.457 | 0.457 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.045 | 0.457 | 0.457 |
Onchocerca volvulus | 0.045 | 0.457 | 0.5208 | |
Loa Loa (eye worm) | hypothetical protein | 0.045 | 0.457 | 0.5208 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.045 | 0.457 | 0.5208 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.045 | 0.457 | 0.457 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.045 | 0.457 | 0.457 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0052 | 0.0259 | 0.0259 |
Echinococcus multilocularis | g protein coupled receptor | 0.045 | 0.457 | 0.457 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0052 | 0.0259 | 0.0295 |
Loa Loa (eye worm) | hypothetical protein | 0.045 | 0.457 | 0.5208 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.045 | 0.457 | 0.457 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.045 | 0.457 | 0.457 |
Schistosoma mansoni | opsin-like receptor | 0.045 | 0.457 | 0.457 |
Echinococcus granulosus | neuropeptides capa receptor | 0.045 | 0.457 | 0.457 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.045 | 0.457 | 0.457 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.045 | 0.457 | 0.457 |
Loa Loa (eye worm) | hypothetical protein | 0.045 | 0.457 | 0.5208 |
Loa Loa (eye worm) | hypothetical protein | 0.045 | 0.457 | 0.5208 |
Brugia malayi | hypothetical protein | 0.045 | 0.457 | 0.5208 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.045 | 0.457 | 0.457 |
Schistosoma mansoni | hypothetical protein | 0.045 | 0.457 | 0.457 |
Schistosoma mansoni | thyroid hormone receptor | 0.0052 | 0.0259 | 0.0259 |
Brugia malayi | hypothetical protein | 0.045 | 0.457 | 0.5208 |
Echinococcus multilocularis | g-protein coupled receptor | 0.045 | 0.457 | 0.457 |
Loa Loa (eye worm) | hypothetical protein | 0.045 | 0.457 | 0.5208 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.045 | 0.457 | 0.457 |
Echinococcus multilocularis | serotonin receptor | 0.045 | 0.457 | 0.457 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.045 | 0.457 | 0.457 |
Echinococcus granulosus | orexin receptor type 2 | 0.045 | 0.457 | 0.457 |
Echinococcus granulosus | somatostatin receptor | 0.045 | 0.457 | 0.457 |
Brugia malayi | G-protein coupled receptor | 0.045 | 0.457 | 0.5208 |
Onchocerca volvulus | 0.045 | 0.457 | 0.5208 | |
Loa Loa (eye worm) | hypothetical protein | 0.045 | 0.457 | 0.5208 |
Schistosoma mansoni | neuropeptide receptor | 0.045 | 0.457 | 0.457 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0052 | 0.0259 | 0.0295 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.045 | 0.457 | 0.457 |
Onchocerca volvulus | 0.045 | 0.457 | 0.5208 | |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.045 | 0.457 | 0.457 |
Onchocerca volvulus | 0.0052 | 0.0259 | 0.0295 | |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0259 | 0.0295 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0052 | 0.0259 | 0.0259 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.045 | 0.457 | 0.457 |
Loa Loa (eye worm) | hypothetical protein | 0.045 | 0.457 | 0.5208 |
Schistosoma mansoni | neuropeptide receptor | 0.045 | 0.457 | 0.457 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.045 | 0.457 | 0.457 |
Onchocerca volvulus | 0.045 | 0.457 | 0.5208 | |
Onchocerca volvulus | 0.045 | 0.457 | 0.5208 | |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.045 | 0.457 | 0.5208 |
Brugia malayi | neuropeptide F receptor | 0.045 | 0.457 | 0.5208 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0052 | 0.0259 | 0.0295 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0052 | 0.0259 | 0.0295 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.045 | 0.457 | 0.457 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0052 | 0.0259 | 0.0295 |
Schistosoma mansoni | biogenic amine receptor | 0.045 | 0.457 | 0.457 |
Echinococcus multilocularis | g protein coupled receptor | 0.045 | 0.457 | 0.457 |
Schistosoma mansoni | amine GPCR | 0.045 | 0.457 | 0.457 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0052 | 0.0259 | 0.0259 |
Echinococcus granulosus | g-protein coupled receptor | 0.045 | 0.457 | 0.457 |
Echinococcus multilocularis | neuropeptide receptor | 0.045 | 0.457 | 0.457 |
Brugia malayi | G-protein coupled receptor | 0.045 | 0.457 | 0.5208 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.045 | 0.457 | 0.457 |
Onchocerca volvulus | 0.045 | 0.457 | 0.5208 | |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.045 | 0.457 | 0.457 |
Brugia malayi | Dopamine receptor protein 1 | 0.045 | 0.457 | 0.5208 |
Loa Loa (eye worm) | hypothetical protein | 0.045 | 0.457 | 0.5208 |
Schistosoma mansoni | tyrosine kinase | 0.0951 | 1 | 1 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.045 | 0.457 | 0.457 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.045 | 0.457 | 0.457 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.045 | 0.457 | 0.457 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.045 | 0.457 | 0.457 |
Loa Loa (eye worm) | hypothetical protein | 0.045 | 0.457 | 0.5208 |
Loa Loa (eye worm) | hypothetical protein | 0.045 | 0.457 | 0.5208 |
Loa Loa (eye worm) | hypothetical protein | 0.045 | 0.457 | 0.5208 |
Brugia malayi | follicle stimulating hormone receptor | 0.045 | 0.457 | 0.5208 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.045 | 0.457 | 0.5208 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.045 | 0.457 | 0.457 |
Onchocerca volvulus | 0.045 | 0.457 | 0.5208 | |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0259 | 0.0295 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0052 | 0.0259 | 0.0259 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.045 | 0.457 | 0.457 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.045 | 0.457 | 0.457 |
Onchocerca volvulus | 0.045 | 0.457 | 0.5208 | |
Loa Loa (eye worm) | hypothetical protein | 0.045 | 0.457 | 0.5208 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0052 | 0.0259 | 0.0259 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0052 | 0.0259 | 0.0259 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0052 | 0.0259 | 0.0259 |
Echinococcus granulosus | neuropeptide s receptor | 0.045 | 0.457 | 0.457 |
Echinococcus multilocularis | fmrfamide receptor | 0.045 | 0.457 | 0.457 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.045 | 0.457 | 0.457 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.045 | 0.457 | 0.457 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0259 | 0.0295 |
Brugia malayi | G protein-coupled receptor | 0.045 | 0.457 | 0.5208 |
Schistosoma mansoni | opsin-like receptor | 0.045 | 0.457 | 0.457 |
Brugia malayi | hypothetical protein | 0.045 | 0.457 | 0.5208 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.045 | 0.457 | 0.457 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.045 | 0.457 | 0.5208 |
Echinococcus granulosus | serotonin receptor | 0.045 | 0.457 | 0.457 |
Brugia malayi | Dopamine receptor protein 2 | 0.045 | 0.457 | 0.5208 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.045 | 0.457 | 0.457 |
Echinococcus granulosus | neuropeptide receptor | 0.045 | 0.457 | 0.457 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.045 | 0.457 | 0.5208 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.045 | 0.457 | 0.457 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.045 | 0.457 | 0.457 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.045 | 0.457 | 0.457 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.045 | 0.457 | 0.457 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.045 | 0.457 | 0.457 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.045 | 0.457 | 0.457 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.045 | 0.457 | 0.457 |
Loa Loa (eye worm) | TYRA-2 protein | 0.045 | 0.457 | 0.5208 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.045 | 0.457 | 0.457 |
Schistosoma mansoni | neuropeptide receptor | 0.045 | 0.457 | 0.457 |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.045 | 0.457 | 0.5208 |
Loa Loa (eye worm) | hypothetical protein | 0.045 | 0.457 | 0.5208 |
Loa Loa (eye worm) | hypothetical protein | 0.045 | 0.457 | 0.5208 |
Brugia malayi | hypothetical protein | 0.045 | 0.457 | 0.5208 |
Echinococcus multilocularis | somatostatin receptor | 0.045 | 0.457 | 0.457 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.045 | 0.457 | 0.457 |
Loa Loa (eye worm) | hypothetical protein | 0.045 | 0.457 | 0.5208 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.045 | 0.457 | 0.457 |
Schistosoma mansoni | opsin-like receptor | 0.045 | 0.457 | 0.457 |
Echinococcus multilocularis | neuropeptide receptor | 0.045 | 0.457 | 0.457 |
Echinococcus multilocularis | fmrfamide receptor | 0.045 | 0.457 | 0.457 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.045 | 0.457 | 0.457 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0052 | 0.0259 | 0.0295 |
Loa Loa (eye worm) | hypothetical protein | 0.045 | 0.457 | 0.5208 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0052 | 0.0259 | 0.0295 |
Brugia malayi | hypothetical protein | 0.045 | 0.457 | 0.5208 |
Echinococcus granulosus | neuropeptide Y receptor | 0.045 | 0.457 | 0.457 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0259 | 0.0295 |
Echinococcus granulosus | allatostatin A receptor | 0.045 | 0.457 | 0.457 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.045 | 0.457 | 0.5208 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0052 | 0.0259 | 0.0259 |
Brugia malayi | AKH receptor | 0.045 | 0.457 | 0.5208 |
Schistosoma mansoni | amine GPCR | 0.045 | 0.457 | 0.457 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0052 | 0.0259 | 0.0259 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.045 | 0.457 | 0.457 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0052 | 0.0259 | 0.0259 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.045 | 0.457 | 0.457 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0052 | 0.0259 | 0.0259 |
Echinococcus granulosus | g protein coupled receptor | 0.045 | 0.457 | 0.457 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.045 | 0.457 | 0.457 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.045 | 0.457 | 0.457 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.045 | 0.457 | 0.457 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0052 | 0.0259 | 0.0259 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.045 | 0.457 | 0.457 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.045 | 0.457 | 0.457 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0052 | 0.0259 | 0.0259 |
Loa Loa (eye worm) | hypothetical protein | 0.045 | 0.457 | 0.5208 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.045 | 0.457 | 0.5208 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.045 | 0.457 | 0.457 |
Brugia malayi | nuclear receptor NHR-88 | 0.0052 | 0.0259 | 0.0295 |
Onchocerca volvulus | 0.045 | 0.457 | 0.5208 | |
Loa Loa (eye worm) | hypothetical protein | 0.045 | 0.457 | 0.5208 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.045 | 0.457 | 0.457 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0052 | 0.0259 | 0.0295 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.045 | 0.457 | 0.457 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0052 | 0.0259 | 0.0295 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.045 | 0.457 | 0.457 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.045 | 0.457 | 0.457 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0052 | 0.0259 | 0.0259 |
Loa Loa (eye worm) | hypothetical protein | 0.045 | 0.457 | 0.5208 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.045 | 0.457 | 0.457 |
Brugia malayi | sulfakinin receptor protein | 0.045 | 0.457 | 0.5208 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0838 | 0.8776 | 1 |
Brugia malayi | ecdysteroid receptor | 0.0838 | 0.8776 | 1 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.045 | 0.457 | 0.457 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0052 | 0.0259 | 0.0295 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.045 | 0.457 | 0.457 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0052 | 0.0259 | 0.0295 |
Onchocerca volvulus | 0.045 | 0.457 | 0.5208 | |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.045 | 0.457 | 0.5208 |
Brugia malayi | larval opioid receptor | 0.045 | 0.457 | 0.5208 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
FC (functional) | = 2.5 | Vasoconstrictive activity in human at 0.02 to 0.18 ug applied topically by paper-patch test relative to betamethasone 17-valerate | ChEMBL. | 874962 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.