Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Wolbachia endosymbiont of Brugia malayi | enoyl-ACP reductase | 0.0565 | 1 | 1 |
Plasmodium vivax | multidomain scavenger receptor, putative | 0.002 | 0.0113 | 0.0113 |
Loa Loa (eye worm) | hypothetical protein | 0.0103 | 0.1628 | 0.2435 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0064 | 0.091 | 0.1358 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.009 | 0.1377 | 0.1377 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.002 | 0.0113 | 0.019 |
Wolbachia endosymbiont of Brugia malayi | Short-chain alcohol dehydrogenase family enzyme | 0.0038 | 0.0447 | 0.0447 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0021 | 0.0136 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0342 | 0.5964 | 1 |
Mycobacterium leprae | conserved hypothetical protein | 0.0078 | 0.1177 | 0.0764 |
Brugia malayi | RNA binding protein | 0.0064 | 0.091 | 0.1363 |
Echinococcus granulosus | geminin | 0.0342 | 0.5964 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0297 | 0.0441 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0382 | 0.6677 | 1 |
Schistosoma mansoni | Smad4 | 0.0026 | 0.0225 | 0.0377 |
Mycobacterium leprae | NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE) | 0.0565 | 1 | 1 |
Echinococcus multilocularis | muscleblind protein | 0.0155 | 0.2565 | 0.43 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.1177 | 0.1759 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0382 | 0.6677 | 1 |
Plasmodium vivax | 3-oxoacyl-[acyl-carrier-protein] reductase, putative | 0.0038 | 0.0447 | 0.0447 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0078 | 0.1177 | 0.1974 |
Loa Loa (eye worm) | RNA binding protein | 0.0064 | 0.091 | 0.1358 |
Loa Loa (eye worm) | hypothetical protein | 0.0155 | 0.2565 | 0.3838 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0078 | 0.1177 | 0.1177 |
Mycobacterium ulcerans | lipase LipD | 0.0078 | 0.1177 | 0.1177 |
Onchocerca volvulus | 0.0096 | 0.1502 | 0.3767 | |
Toxoplasma gondii | 2,4-dienoyl CoA reductase 2, peroxisomal family protein | 0.0038 | 0.0447 | 0.0447 |
Echinococcus multilocularis | Smad4 | 0.0026 | 0.0225 | 0.0377 |
Mycobacterium tuberculosis | Possible 20-beta-hydroxysteroid dehydrogenase FabG3 (cortisone reductase) ((R)-20-hydroxysteroid dehydrogenase) | 0.0038 | 0.0447 | 0.0447 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.003 | 0.0297 | 0.0499 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0078 | 0.1177 | 0.1177 |
Schistosoma mansoni | smad1 5 8 and | 0.0026 | 0.0225 | 0.0377 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0119 | 0.1907 | 0.3197 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0021 | 0.0136 | 0.1154 |
Leishmania major | 3-oxoacyl-ACP reductase, putative | 0.0038 | 0.0447 | 0.3799 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0048 | 0.0621 | 0.1042 |
Schistosoma mansoni | hypothetical protein | 0.0103 | 0.1628 | 0.2731 |
Leishmania major | trypanothione reductase | 0.0039 | 0.0465 | 0.3951 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0078 | 0.1177 | 0.1177 |
Schistosoma mansoni | hypothetical protein | 0.0342 | 0.5964 | 1 |
Trypanosoma brucei | pteridine reductase 1 | 0.0038 | 0.0447 | 0.3799 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.0038 | 0.0447 | 0.0447 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0038 | 0.0447 | 0.0447 |
Brugia malayi | hypothetical protein | 0.002 | 0.0113 | 0.017 |
Brugia malayi | MH2 domain containing protein | 0.0026 | 0.0225 | 0.0337 |
Trypanosoma brucei | glycosyl hydrolase-like protein | 0.0014 | 0.0003 | 0.0028 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0038 | 0.0447 | 0.0447 |
Schistosoma mansoni | hypothetical protein | 0.0023 | 0.0168 | 0.0282 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0028 | 0.0265 | 0.0445 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0075 | 0.1116 | 0.1871 |
Toxoplasma gondii | 3-ketoacyl-(acyl-carrier-protein) reductase | 0.0038 | 0.0447 | 0.0447 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0078 | 0.1177 | 0.1177 |
Leishmania major | hypothetical protein, conserved | 0.0051 | 0.0678 | 0.5761 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0021 | 0.0136 | 0.0136 |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0038 | 0.0447 | 0.0665 |
Brugia malayi | Pre-SET motif family protein | 0.0205 | 0.3471 | 0.5198 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0501 | 0.8851 | 0.8851 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0021 | 0.0136 | 0.0204 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0037 | 0.0424 | 0.0636 |
Plasmodium vivax | enoyl-acyl carrier protein reductase | 0.0565 | 1 | 1 |
Onchocerca volvulus | 0.002 | 0.0113 | 0.0277 | |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0038 | 0.0447 | 0.0447 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0038 | 0.0447 | 0.0447 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0037 | 0.0424 | 0.3785 |
Onchocerca volvulus | 0.0078 | 0.1177 | 0.295 | |
Loa Loa (eye worm) | beta-lactamase | 0.0078 | 0.1177 | 0.1759 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0078 | 0.1177 | 0.1177 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0037 | 0.0424 | 0.0424 |
Onchocerca volvulus | 0.0078 | 0.1177 | 0.295 | |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0038 | 0.0447 | 0.0447 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0037 | 0.0424 | 0.0424 |
Brugia malayi | Smad1 | 0.0026 | 0.0225 | 0.0337 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0048 | 0.063 | 0.1057 |
Brugia malayi | MH2 domain containing protein | 0.0382 | 0.6677 | 1 |
Brugia malayi | Doublecortin family protein | 0.002 | 0.0113 | 0.017 |
Trypanosoma cruzi | oxidoreductase-like protein, putative | 0.0038 | 0.0447 | 0.3799 |
Leishmania major | glycosyl hydrolase-like protein | 0.0014 | 0.0003 | 0.0028 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0037 | 0.0424 | 0.0712 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.002 | 0.0113 | 0.019 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0021 | 0.0136 | 0.0199 |
Echinococcus granulosus | cpg binding protein | 0.0034 | 0.0371 | 0.0622 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0167 | 0.2777 | 0.416 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0119 | 0.1907 | 0.3197 |
Mycobacterium leprae | Probable lipase LipE | 0.0078 | 0.1177 | 0.0764 |
Trypanosoma cruzi | beta-ketoacyl-ACP reductase | 0.0038 | 0.0447 | 0.3799 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0051 | 0.0678 | 0.0678 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0167 | 0.2777 | 0.4657 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.004 | 0.0475 | 0.0796 |
Echinococcus granulosus | muscleblind protein | 0.0155 | 0.2565 | 0.43 |
Loa Loa (eye worm) | oxidoreductase | 0.0038 | 0.0447 | 0.0665 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0078 | 0.1177 | 0.1177 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0048 | 0.0621 | 0.093 |
Entamoeba histolytica | hypothetical protein | 0.0075 | 0.1116 | 1 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0037 | 0.0424 | 0.0424 |
Echinococcus granulosus | RUN | 0.002 | 0.0113 | 0.019 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0297 | 0.0499 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.1177 | 0.1759 |
Brugia malayi | beta-lactamase family protein | 0.0078 | 0.1177 | 0.1763 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0014 | 0.0003 | 0.0003 |
Brugia malayi | hypothetical protein | 0.0075 | 0.1116 | 0.1671 |
Brugia malayi | MH1 domain containing protein | 0.0014 | 0.0014 | 0.0021 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0038 | 0.0447 | 0.0447 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0039 | 0.0465 | 0.0465 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0021 | 0.0136 | 1 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.0038 | 0.0447 | 0.0447 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0099 | 0.1558 | 0.1558 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.091 | 0.1526 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0038 | 0.0447 | 0.0447 |
Trichomonas vaginalis | hypothetical protein | 0.0565 | 1 | 1 |
Loa Loa (eye worm) | doublecortin family protein | 0.002 | 0.0113 | 0.0165 |
Mycobacterium tuberculosis | Conserved protein | 0.0078 | 0.1177 | 0.1177 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0023 | 0.0168 | 0.0282 |
Plasmodium falciparum | thioredoxin reductase | 0.0039 | 0.0465 | 0.0465 |
Echinococcus granulosus | smad | 0.0026 | 0.0225 | 0.0377 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0078 | 0.1177 | 0.1177 |
Brugia malayi | beta-lactamase family protein | 0.0078 | 0.1177 | 0.1763 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0103 | 0.1628 | 0.2439 |
Schistosoma mansoni | cpg binding protein | 0.0034 | 0.0371 | 0.0622 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0151 | 0.2496 | 0.3739 |
Schistosoma mansoni | ap endonuclease | 0.0021 | 0.0136 | 0.0228 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0021 | 0.0136 | 0.1154 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0113 | 0.0165 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.091 | 0.1526 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.002 | 0.0113 | 0.019 |
Trypanosoma brucei | glucosidase, putative | 0.0037 | 0.0424 | 0.3604 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0051 | 0.0678 | 0.0678 |
Echinococcus multilocularis | smad | 0.0026 | 0.0225 | 0.0377 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.0621 | 0.1042 |
Brugia malayi | MH1 domain containing protein | 0.0026 | 0.0225 | 0.0337 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0026 | 0.0225 | 0.0377 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0038 | 0.0447 | 0.0447 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0026 | 0.0225 | 0.0332 |
Loa Loa (eye worm) | hypothetical protein | 0.0155 | 0.2565 | 0.3838 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0048 | 0.0621 | 0.1042 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0021 | 0.0136 | 0.0228 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0048 | 0.0621 | 0.1042 |
Brugia malayi | TAR-binding protein | 0.0064 | 0.091 | 0.1363 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0021 | 0.0136 | 0.0136 |
Plasmodium vivax | SET domain protein, putative | 0.003 | 0.0297 | 0.0297 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.003 | 0.0297 | 0.0297 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.0038 | 0.0447 | 0.0447 |
Schistosoma mansoni | smad | 0.0026 | 0.0225 | 0.0377 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0048 | 0.063 | 0.1057 |
Mycobacterium ulcerans | oxidoreductase | 0.0038 | 0.0447 | 0.0447 |
Schistosoma mansoni | alpha-glucosidase | 0.0143 | 0.2356 | 0.3951 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0062 | 0.088 | 0.088 |
Mycobacterium tuberculosis | NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase) | 0.0565 | 1 | 1 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.003 | 0.0297 | 0.0499 |
Schistosoma mansoni | lipoxygenase | 0.0083 | 0.1259 | 0.211 |
Brugia malayi | Thioredoxin reductase | 0.0039 | 0.0465 | 0.0697 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0048 | 0.063 | 0.0939 |
Schistosoma mansoni | polycystin 1-related | 0.002 | 0.0113 | 0.019 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0051 | 0.0678 | 0.5761 |
Onchocerca volvulus | 0.003 | 0.0297 | 0.0739 | |
Entamoeba histolytica | hypothetical protein | 0.0075 | 0.1116 | 1 |
Plasmodium falciparum | glutathione reductase | 0.0039 | 0.0465 | 0.0465 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0021 | 0.0136 | 0.1154 |
Leishmania major | oxidoreductase-like protein | 0.0038 | 0.0447 | 0.3799 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.1177 | 0.1759 |
Entamoeba histolytica | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.0038 | 0.0447 | 0.3991 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.0621 | 0.1042 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0099 | 0.1558 | 0.1558 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.003 | 0.0297 | 0.0499 |
Onchocerca volvulus | 0.0038 | 0.0447 | 0.1116 | |
Onchocerca volvulus | 0.0233 | 0.3983 | 1 | |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.002 | 0.0113 | 0.019 |
Brugia malayi | hypothetical protein | 0.0033 | 0.035 | 0.0525 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0037 | 0.0424 | 0.0424 |
Trichomonas vaginalis | set domain proteins, putative | 0.0233 | 0.3983 | 0.3983 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.004 | 0.0475 | 0.0796 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0037 | 0.0424 | 0.0424 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.1177 | 0.1759 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0037 | 0.0424 | 0.0424 |
Echinococcus granulosus | Polycystic kidney disease protein | 0.002 | 0.0113 | 0.019 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0048 | 0.0621 | 0.1042 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0078 | 0.1177 | 0.1177 |
Trypanosoma cruzi | glycosyl hydrolase-like protein, putative | 0.0014 | 0.0003 | 0.0028 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.1177 | 0.1759 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0026 | 0.0225 | 0.0332 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0032 | 0.0338 | 0.0501 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0078 | 0.1177 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.1177 | 0.1759 |
Schistosoma mansoni | hypothetical protein | 0.0075 | 0.1116 | 0.1871 |
Brugia malayi | MH2 domain containing protein | 0.0026 | 0.0225 | 0.0337 |
Echinococcus multilocularis | cpg binding protein | 0.0034 | 0.0371 | 0.0622 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0014 | 0.0016 |
Mycobacterium tuberculosis | Probable reductase | 0.009 | 0.1377 | 0.1377 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.0424 | 0.3604 |
Brugia malayi | CXXC zinc finger family protein | 0.0032 | 0.0338 | 0.0506 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0297 | 0.0499 |
Schistosoma mansoni | lipoxygenase | 0.0119 | 0.1907 | 0.3197 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.063 | 0.1057 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.009 | 0.1377 | 0.1377 |
Schistosoma mansoni | ap endonuclease | 0.0021 | 0.0136 | 0.0228 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0048 | 0.0621 | 0.093 |
Echinococcus granulosus | 3 oxoacyl acyl carrier protein reductase | 0.0038 | 0.0447 | 0.075 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0038 | 0.0447 | 0.0447 |
Loa Loa (eye worm) | TAR-binding protein | 0.0064 | 0.091 | 0.1358 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.091 | 0.1526 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0621 | 0.0926 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0151 | 0.2496 | 0.3739 |
Plasmodium vivax | hypothetical protein, conserved | 0.0078 | 0.1177 | 0.1177 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0205 | 0.3471 | 0.5196 |
Trichomonas vaginalis | esterase, putative | 0.0078 | 0.1177 | 0.1177 |
Chlamydia trachomatis | oxoacy-ACP reductase | 0.0038 | 0.0447 | 0.0447 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0078 | 0.1177 | 0.1177 |
Loa Loa (eye worm) | retinol dehydrogenase 12 | 0.0038 | 0.0447 | 0.0665 |
Toxoplasma gondii | ABC1 family protein | 0.0078 | 0.1177 | 0.1177 |
Toxoplasma gondii | thioredoxin reductase | 0.0039 | 0.0465 | 0.0465 |
Schistosoma mansoni | loxhd1 | 0.002 | 0.0113 | 0.019 |
Mycobacterium tuberculosis | Possible oxidoreductase | 0.0038 | 0.0447 | 0.0447 |
Echinococcus granulosus | GPCR family 2 | 0.0048 | 0.0621 | 0.1042 |
Brugia malayi | Muscleblind-like protein | 0.0155 | 0.2565 | 0.3841 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0048 | 0.0621 | 0.0926 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0078 | 0.1177 | 1 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0051 | 0.0678 | 0.5761 |
Leishmania major | pteridine reductase 1 | 0.0038 | 0.0447 | 0.3799 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0048 | 0.063 | 0.1057 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0038 | 0.0447 | 0.0447 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0037 | 0.0424 | 0.0424 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.009 | 0.1377 | 0.0973 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0014 | 0.0003 | 0.0003 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0039 | 0.0465 | 0.0465 |
Mycobacterium tuberculosis | Probable 3-oxoacyl-[acyl-carrier protein] reductase FabG2 (3-ketoacyl-acyl carrier protein reductase) | 0.0038 | 0.0447 | 0.0447 |
Schistosoma mansoni | rab6-interacting | 0.002 | 0.0113 | 0.019 |
Schistosoma mansoni | cpg binding protein | 0.0034 | 0.0371 | 0.0622 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0078 | 0.1177 | 0.1177 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0037 | 0.0424 | 0.3604 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0038 | 0.0447 | 0.0447 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0064 | 0.091 | 0.1363 |
Entamoeba histolytica | hypothetical protein | 0.0075 | 0.1116 | 1 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0014 | 0.0003 | 0.0005 |
Plasmodium falciparum | enoyl-acyl carrier reductase | 0.0565 | 1 | 1 |
Toxoplasma gondii | enoyl-acyl carrier reductase ENR | 0.0565 | 1 | 1 |
Plasmodium falciparum | LCCL domain-containing protein | 0.002 | 0.0113 | 0.0113 |
Schistosoma mansoni | dihydropteridine reductase | 0.0038 | 0.0447 | 0.075 |
Brugia malayi | hypothetical protein | 0.002 | 0.0113 | 0.017 |
Schistosoma mansoni | rab6-interacting | 0.002 | 0.0113 | 0.019 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.0621 | 0.1042 |
Plasmodium vivax | glutathione reductase, putative | 0.0039 | 0.0465 | 0.0465 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0037 | 0.0424 | 0.0424 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0014 | 0.0003 | 0.0003 |
Toxoplasma gondii | short chain dehydrogenase family protein, putative | 0.0038 | 0.0447 | 0.0447 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0078 | 0.1177 | 0.1177 |
Brugia malayi | MH1 domain containing protein | 0.0026 | 0.0225 | 0.0337 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0078 | 0.1177 | 0.1177 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0023 | 0.0168 | 0.0282 |
Mycobacterium ulcerans | 3-oxoacyl-ACP reductase | 0.0038 | 0.0447 | 0.0447 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0037 | 0.0424 | 0.0631 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0167 | 0.2777 | 0.4657 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0037 | 0.0424 | 0.0424 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0021 | 0.0136 | 0.0136 |
Mycobacterium ulcerans | beta-lactamase | 0.0078 | 0.1177 | 0.1177 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0075 | 0.1116 | 0.1871 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.0424 | 0.3604 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.0621 | 0.1042 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.063 | 0.1057 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0037 | 0.0424 | 0.0712 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0038 | 0.0447 | 0.0447 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0014 | 0.0003 | 0.0003 |
Echinococcus granulosus | tar DNA binding protein | 0.0064 | 0.091 | 0.1526 |
Echinococcus multilocularis | tar DNA binding protein | 0.0064 | 0.091 | 0.1526 |
Schistosoma mansoni | cpg binding protein | 0.0032 | 0.0338 | 0.0566 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0447 | 0.0665 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0021 | 0.0136 | 0.1192 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0021 | 0.0136 | 0.1154 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0039 | 0.0465 | 0.0692 |
Plasmodium falciparum | 3-oxoacyl-[acyl-carrier-protein] reductase | 0.0038 | 0.0447 | 0.0447 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0038 | 0.0447 | 0.0447 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0026 | 0.0225 | 0.0377 |
Mycobacterium ulcerans | 3-oxoacyl-ACP reductase | 0.0038 | 0.0447 | 0.0447 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0014 | 0.0003 | 0.0003 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0038 | 0.0447 | 0.0447 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0014 | 0.0003 | 0.0003 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0021 | 0.0136 | 0.0228 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0021 | 0.0136 | 0.0136 |
Schistosoma mansoni | hypothetical protein | 0.002 | 0.0113 | 0.019 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0038 | 0.0447 | 0.0447 |
Onchocerca volvulus | 0.0032 | 0.0338 | 0.084 | |
Echinococcus multilocularis | 3 oxoacyl acyl carrier protein reductase | 0.0038 | 0.0447 | 0.075 |
Mycobacterium tuberculosis | Probable dehydrogenase/reductase | 0.0038 | 0.0447 | 0.0447 |
Trypanosoma brucei | oxidoreductase-like protein | 0.0038 | 0.0447 | 0.3799 |
Mycobacterium ulcerans | hypothetical protein | 0.0078 | 0.1177 | 0.1177 |
Entamoeba histolytica | hypothetical protein | 0.0075 | 0.1116 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0078 | 0.1177 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0113 | 0.0165 |
Trypanosoma cruzi | beta-ketoacyl-ACP reductase | 0.0038 | 0.0447 | 0.3799 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0155 | 0.2565 | 0.43 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0021 | 0.0136 | 0.0136 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0678 | 0.1012 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0037 | 0.0424 | 0.0424 |
Brugia malayi | Pre-SET motif family protein | 0.003 | 0.0297 | 0.0446 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0078 | 0.1177 | 0.1177 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0099 | 0.1558 | 0.1163 |
Schistosoma mansoni | smad1 5 8 and | 0.0026 | 0.0225 | 0.0377 |
Toxoplasma gondii | exonuclease III APE | 0.0021 | 0.0136 | 0.0136 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.009 | 0.1377 | 0.1377 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0078 | 0.1177 | 0.1759 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0014 | 0.0003 | 0.0003 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0167 | 0.2777 | 0.4657 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0038 | 0.0447 | 0.0447 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0078 | 0.1177 | 0.1974 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0038 | 0.0447 | 0.067 |
Mycobacterium ulcerans | 3-alpha-hydroxysteroid dehydrogenase | 0.0038 | 0.0447 | 0.0447 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.003 | 0.0297 | 0.0499 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0038 | 0.0447 | 0.067 |
Echinococcus multilocularis | Polycystic kidney disease protein | 0.002 | 0.0113 | 0.019 |
Leishmania major | dehydrogenase/oxidoreductase-like protein | 0.0038 | 0.0447 | 0.3799 |
Echinococcus multilocularis | geminin | 0.0342 | 0.5964 | 1 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0078 | 0.1177 | 0.1974 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.091 | 0.1526 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0051 | 0.0678 | 0.0678 |
Mycobacterium tuberculosis | Conserved protein | 0.0078 | 0.1177 | 0.1177 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0051 | 0.0678 | 0.0678 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0038 | 0.0447 | 0.0447 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0037 | 0.0424 | 0.3785 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.009 | 0.1377 | 0.1377 |
Brugia malayi | MH1 domain containing protein | 0.0014 | 0.0014 | 0.0021 |
Loa Loa (eye worm) | glutathione reductase | 0.0039 | 0.0465 | 0.0692 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0151 | 0.2496 | 0.3736 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0048 | 0.063 | 0.1057 |
Mycobacterium tuberculosis | Possible oxidoreductase | 0.0038 | 0.0447 | 0.0447 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0038 | 0.0447 | 0.0447 |
Echinococcus multilocularis | RUN | 0.002 | 0.0113 | 0.019 |
Loa Loa (eye worm) | nuclear factor I | 0.0014 | 0.0014 | 0.0016 |
Trypanosoma brucei | beta-ketoacyl-ACP reductase | 0.0038 | 0.0447 | 0.3799 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0167 | 0.2777 | 0.4157 |
Schistosoma mansoni | smad1 5 8 and | 0.0026 | 0.0225 | 0.0377 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0048 | 0.063 | 0.0944 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0026 | 0.0225 | 0.0377 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0014 | 0.0003 | 0.0003 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.0038 | 0.0447 | 0.0447 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0297 | 0.0499 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0039 | 0.0465 | 0.3951 |
Mycobacterium ulcerans | 20-beta-hydroxysteroid dehydrogenase FabG3 | 0.0038 | 0.0447 | 0.0447 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0038 | 0.0447 | 0.0447 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0038 | 0.0447 | 0.0447 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.091 | 0.1526 |
Brugia malayi | glutathione reductase | 0.0039 | 0.0465 | 0.0697 |
Onchocerca volvulus | 0.002 | 0.0113 | 0.0277 | |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.2496 | 0.3736 |
Loa Loa (eye worm) | Smad1 | 0.0026 | 0.0225 | 0.0332 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0075 | 0.1116 | 0.1871 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0078 | 0.1177 | 0.1177 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0038 | 0.0447 | 0.0447 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0026 | 0.0225 | 0.0377 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0021 | 0.0136 | 0.0136 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0026 | 0.0225 | 0.0377 |
Brugia malayi | beta-lactamase | 0.0078 | 0.1177 | 0.1763 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0038 | 0.0447 | 0.0447 |
Schistosoma mansoni | alpha glucosidase | 0.0037 | 0.0424 | 0.0712 |
Trypanosoma cruzi | glycosyl hydrolase-like protein, putative | 0.0014 | 0.0003 | 0.0028 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.009 | 0.1377 | 0.1377 |
Echinococcus granulosus | Smad4 | 0.0026 | 0.0225 | 0.0377 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0078 | 0.1177 | 0.1763 |
Onchocerca volvulus | 0.0038 | 0.0447 | 0.1116 | |
Trypanosoma brucei | hypothetical protein, conserved | 0.0078 | 0.1177 | 1 |
Mycobacterium ulcerans | enoyl-(acyl carrier protein) reductase | 0.0565 | 1 | 1 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.0038 | 0.0447 | 0.0447 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0078 | 0.1177 | 0.1974 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0051 | 0.0678 | 0.5761 |
Schistosoma mansoni | alpha-glucosidase | 0.0143 | 0.2356 | 0.3951 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.063 | 0.1057 |
Brugia malayi | hypothetical protein | 0.0051 | 0.0678 | 0.1016 |
Leishmania major | dehydrogenase/oxidoreductase-like protein | 0.0038 | 0.0447 | 0.3799 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0099 | 0.1558 | 0.1558 |
Mycobacterium tuberculosis | Conserved protein | 0.0078 | 0.1177 | 0.1177 |
Echinococcus multilocularis | GPCR, family 2 | 0.0048 | 0.0621 | 0.1042 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0038 | 0.0447 | 0.0447 |
Trypanosoma brucei | trypanothione reductase | 0.0039 | 0.0465 | 0.3951 |
Onchocerca volvulus | 0.0078 | 0.1177 | 0.295 | |
Schistosoma mansoni | 3-oxoacyl-[ACP] reductase | 0.0038 | 0.0447 | 0.075 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0021 | 0.0136 | 0.0136 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0038 | 0.0447 | 0.0447 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0069 | 0.1012 | 0.1697 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.