Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | carboxylesterase | 0.0246 | 0.3559 | 1 |
Onchocerca volvulus | 0.0238 | 0.3382 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0246 | 0.3559 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0246 | 0.3559 | 0.3559 |
Echinococcus granulosus | carboxylesterase 5A | 0.0246 | 0.3559 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0093 | 0 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.0246 | 0.3559 | 1 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0238 | 0.3382 | 0.3382 |
Echinococcus multilocularis | acetylcholinesterase | 0.0246 | 0.3559 | 1 |
Toxoplasma gondii | kringle domain-containing protein | 0.0093 | 0 | 0.5 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0246 | 0.3559 | 1 |
Onchocerca volvulus | 0.0208 | 0.2671 | 0.7897 | |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0093 | 0 | 0.5 |
Echinococcus granulosus | acetylcholinesterase | 0.0246 | 0.3559 | 1 |
Plasmodium falciparum | cysteine repeat modular protein 1 | 0.0093 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0238 | 0.3382 | 0.9503 |
Echinococcus granulosus | acetylcholinesterase | 0.0246 | 0.3559 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0246 | 0.3559 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0246 | 0.3559 | 1 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0238 | 0.3382 | 0.3382 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0246 | 0.3559 | 1 |
Plasmodium vivax | cysteine repeat modular protein 1, putative | 0.0093 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0238 | 0.3382 | 0.9503 |
Brugia malayi | Trypsin family protein | 0.0238 | 0.3382 | 0.9503 |
Brugia malayi | Carboxylesterase family protein | 0.0246 | 0.3559 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.