Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | latrophilin 2 splice variant baaae | 0.0028 | 0.1704 | 0.1704 |
Schistosoma mansoni | hypothetical protein | 0.0013 | 0.0511 | 0.1827 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0013 | 0.0511 | 0.1827 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0013 | 0.0511 | 0.0511 |
Schistosoma mansoni | hypothetical protein | 0.0013 | 0.0511 | 0.1827 |
Brugia malayi | RNA binding protein | 0.0042 | 0.2796 | 0.2796 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0041 | 0.2733 | 0.2733 |
Schistosoma mansoni | hypothetical protein | 0.0013 | 0.0511 | 0.1827 |
Schistosoma mansoni | tar DNA-binding protein | 0.0042 | 0.2796 | 1 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0013 | 0.0511 | 0.0511 |
Echinococcus granulosus | GPCR family 2 | 0.0013 | 0.0511 | 0.1827 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.2733 | 0.2733 |
Schistosoma mansoni | tar DNA-binding protein | 0.0042 | 0.2796 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0028 | 0.1704 | 0.6097 |
Schistosoma mansoni | tar DNA-binding protein | 0.0042 | 0.2796 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0042 | 0.2796 | 0.2796 |
Toxoplasma gondii | hypothetical protein | 0.0006 | 0 | 0.5 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0041 | 0.2733 | 0.2733 |
Onchocerca volvulus | Rap guanine nucleotide exchange factor 1 homolog | 0.0132 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0042 | 0.2796 | 1 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0013 | 0.0511 | 0.1827 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0511 | 0.0511 |
Loa Loa (eye worm) | TAR-binding protein | 0.0042 | 0.2796 | 0.2796 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.1704 | 0.1704 |
Echinococcus multilocularis | GPCR, family 2 | 0.0013 | 0.0511 | 0.1827 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0013 | 0.0511 | 0.1827 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0013 | 0.0511 | 0.1827 |
Schistosoma mansoni | tar DNA-binding protein | 0.0042 | 0.2796 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.0042 | 0.2796 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.0042 | 0.2796 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0132 | 1 | 1 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0042 | 0.2796 | 0.2796 |
Brugia malayi | TAR-binding protein | 0.0042 | 0.2796 | 0.2796 |
Schistosoma mansoni | hypothetical protein | 0.0013 | 0.0511 | 0.1827 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0042 | 0.2796 | 0.2796 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0013 | 0.0511 | 0.0511 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0041 | 0.2733 | 0.2733 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.