Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | tubulin gamma chain | 0.0371 | 0.6031 | 0.6031 |
Toxoplasma gondii | alpha-tubulin I, putative | 0.0454 | 0.7462 | 0.7462 |
Loa Loa (eye worm) | cysteine protease | 0.002 | 0.0029 | 0.0029 |
Trypanosoma brucei | zeta tubulin, putative | 0.0481 | 0.7911 | 0.7911 |
Plasmodium vivax | vivapain-2 | 0.002 | 0.0029 | 0.0029 |
Schistosoma mansoni | alpha tubulin | 0.0454 | 0.7462 | 0.7462 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0074 | 0.0966 | 0.0966 |
Brugia malayi | beta-tubulin, identical | 0.0603 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0041 | 0.0389 | 0.0361 |
Brugia malayi | Tubulin alpha chain | 0.0454 | 0.7462 | 0.7462 |
Echinococcus multilocularis | Tubulin beta 2C chain | 0.0603 | 1 | 1 |
Echinococcus granulosus | tubulin alpha chain | 0.0454 | 0.7462 | 0.7462 |
Schistosoma mansoni | tubulin subunit epsilon | 0.037 | 0.6023 | 0.6023 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.002 | 0.0029 | 0.0029 |
Trypanosoma brucei | tubulin gamma chain | 0.0371 | 0.6031 | 0.6031 |
Echinococcus multilocularis | tubulin alpha 3 chain | 0.0454 | 0.7462 | 0.7462 |
Echinococcus granulosus | tubulin subunit beta | 0.0603 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.019 | 0.2947 | 0.2947 |
Plasmodium falciparum | tubulin epsilon chain, putative | 0.037 | 0.6023 | 0.6023 |
Echinococcus granulosus | Tubulin beta 2C chain | 0.0603 | 1 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.002 | 0.0029 | 0.0029 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0029 | 0.0029 |
Leishmania major | cathepsin L-like protease | 0.002 | 0.0029 | 0.0029 |
Trypanosoma brucei | beta tubulin | 0.0339 | 0.5493 | 0.5493 |
Trichomonas vaginalis | tubulin gamma chain, putative | 0.0603 | 1 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.002 | 0.0029 | 0.0029 |
Loa Loa (eye worm) | tubulin alpha chain | 0.0454 | 0.7462 | 0.7462 |
Echinococcus multilocularis | tubulin alpha chain | 0.0454 | 0.7462 | 0.7462 |
Loa Loa (eye worm) | alpha-tubulin | 0.0454 | 0.7462 | 0.7462 |
Leishmania major | cathepsin L-like protease | 0.002 | 0.0029 | 0.0029 |
Plasmodium vivax | tubulin beta chain, putative | 0.0603 | 1 | 1 |
Leishmania major | alpha tubulin | 0.0454 | 0.7462 | 0.7462 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0074 | 0.0966 | 0.0966 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.002 | 0.0029 | 0.0029 |
Trypanosoma brucei | alpha tubulin | 0.0454 | 0.7462 | 0.7462 |
Leishmania major | alpha tubulin | 0.0454 | 0.7462 | 0.7462 |
Echinococcus multilocularis | peroxisome assembly protein 26 | 0.0454 | 0.7462 | 0.7462 |
Plasmodium vivax | tubulin alpha chain, putative | 0.0454 | 0.7462 | 0.7462 |
Plasmodium falciparum | tubulin gamma chain | 0.0371 | 0.6031 | 0.6031 |
Trypanosoma brucei | alpha tubulin | 0.0454 | 0.7462 | 0.7462 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0389 | 0.0389 |
Plasmodium vivax | delta tubulin, putative | 0.0155 | 0.2353 | 0.2353 |
Giardia lamblia | Alpha-tubulin | 0.0454 | 0.7462 | 0.6681 |
Brugia malayi | tubulin alpha chain - mouse | 0.0454 | 0.7462 | 0.7462 |
Brugia malayi | Cell division protein ftsZ | 0.0155 | 0.2353 | 0.2353 |
Trichomonas vaginalis | tubulin alpha-1 chain, putative | 0.0184 | 0.2834 | 0.2814 |
Brugia malayi | hypothetical protein | 0.0041 | 0.0389 | 0.0389 |
Trypanosoma brucei | beta tubulin | 0.0603 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0041 | 0.0389 | 0.0361 |
Schistosoma mansoni | hypothetical protein | 0.0191 | 0.2964 | 0.2964 |
Toxoplasma gondii | tubulin, putative | 0.0031 | 0.0226 | 0.0226 |
Loa Loa (eye worm) | tubulin alpha-2 chain | 0.0454 | 0.7462 | 0.7462 |
Echinococcus granulosus | tubulin alpha | 0.0339 | 0.5493 | 0.5493 |
Brugia malayi | Cathepsin L-like precursor | 0.002 | 0.0029 | 0.0029 |
Loa Loa (eye worm) | BEN-1 protein | 0.0603 | 1 | 1 |
Leishmania major | beta tubulin | 0.0603 | 1 | 1 |
Echinococcus multilocularis | tubulin alpha chain | 0.0454 | 0.7462 | 0.7462 |
Echinococcus granulosus | single minded 2 | 0.0042 | 0.0413 | 0.0413 |
Echinococcus multilocularis | beta tubulin | 0.0603 | 1 | 1 |
Trypanosoma cruzi | tubulin gamma chain | 0.0371 | 0.6031 | 0.6031 |
Leishmania major | alpha tubulin | 0.0454 | 0.7462 | 0.7462 |
Plasmodium vivax | tubulin alpha chain, putative | 0.0454 | 0.7462 | 0.7462 |
Echinococcus granulosus | Tubulin alpha 1 chain | 0.0454 | 0.7462 | 0.7462 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.002 | 0.0029 | 0.0029 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.0454 | 0.7462 | 0.7455 |
Echinococcus granulosus | Tubulin alpha 1 chain | 0.0454 | 0.7462 | 0.7462 |
Schistosoma mansoni | alpha tubulin | 0.0454 | 0.7462 | 0.7462 |
Brugia malayi | bHLH-PAS transcription factor | 0.0042 | 0.0413 | 0.0413 |
Leishmania major | cathepsin L-like protease | 0.002 | 0.0029 | 0.0029 |
Schistosoma mansoni | aryl hydrocarbon receptor | 0.0057 | 0.0664 | 0.0664 |
Schistosoma mansoni | tubulin subunit beta | 0.0603 | 1 | 1 |
Trichomonas vaginalis | tubulin gamma chain, putative | 0.0155 | 0.2353 | 0.2331 |
Leishmania major | beta tubulin | 0.0603 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0074 | 0.0966 | 0.0966 |
Giardia lamblia | Gamma tubulin | 0.0371 | 0.6031 | 0.4809 |
Echinococcus granulosus | Tubulin alpha 1 chain | 0.0454 | 0.7462 | 0.7462 |
Leishmania major | cathepsin L-like protease | 0.0074 | 0.0966 | 0.0966 |
Echinococcus multilocularis | beta tubulin | 0.0603 | 1 | 1 |
Echinococcus multilocularis | Tubulin beta 2C chain | 0.0603 | 1 | 1 |
Leishmania major | alpha tubulin | 0.0454 | 0.7462 | 0.7462 |
Leishmania major | beta tubulin | 0.0603 | 1 | 1 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0041 | 0.0389 | 0.0389 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.002 | 0.0029 | 0.0029 |
Schistosoma mansoni | tubulin subunit beta | 0.0603 | 1 | 1 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.0603 | 1 | 1 |
Brugia malayi | Tubulin alpha-2 chain | 0.0454 | 0.7462 | 0.7462 |
Loa Loa (eye worm) | BEN-1 protein | 0.0603 | 1 | 1 |
Echinococcus multilocularis | tubulin subunit beta | 0.0603 | 1 | 1 |
Schistosoma mansoni | tubulin subunit alpha | 0.0155 | 0.2353 | 0.2353 |
Echinococcus granulosus | tubulin alpha 1C chain | 0.0454 | 0.7462 | 0.7462 |
Schistosoma mansoni | tubulin subunit beta | 0.0603 | 1 | 1 |
Loa Loa (eye worm) | tubulin beta-2A chain | 0.0603 | 1 | 1 |
Echinococcus granulosus | tubulin beta 1 chain | 0.0603 | 1 | 1 |
Echinococcus multilocularis | tubulin alpha 1C chain | 0.0454 | 0.7462 | 0.7462 |
Brugia malayi | hypoxia-induced factor 1 | 0.0175 | 0.2695 | 0.2695 |
Echinococcus multilocularis | tubulin gamma 1 chain | 0.0371 | 0.6031 | 0.6031 |
Loa Loa (eye worm) | tubulin alpha chain | 0.0454 | 0.7462 | 0.7462 |
Toxoplasma gondii | beta-tubulin, putative | 0.0603 | 1 | 1 |
Leishmania major | zeta tubulin, putative | 0.0481 | 0.7911 | 0.7911 |
Leishmania major | beta tubulin | 0.0603 | 1 | 1 |
Toxoplasma gondii | tubulin/FtsZ family, GTPase domain-containing protein | 0.0186 | 0.2884 | 0.2884 |
Echinococcus granulosus | geminin | 0.0191 | 0.2964 | 0.2964 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0155 | 0.2353 | 0.2331 |
Brugia malayi | Cathepsin L-like precursor | 0.002 | 0.0029 | 0.0029 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.003 | 0.0216 | 0.0216 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.002 | 0.0029 | 0.0029 |
Echinococcus multilocularis | geminin | 0.0191 | 0.2964 | 0.2964 |
Leishmania major | alpha tubulin | 0.0454 | 0.7462 | 0.7462 |
Trichomonas vaginalis | tubulin epsilon chain, putative | 0.0603 | 1 | 1 |
Leishmania major | beta tubulin | 0.0603 | 1 | 1 |
Echinococcus granulosus | tubulin alpha 3 chain | 0.0454 | 0.7462 | 0.7462 |
Trypanosoma brucei | beta tubulin | 0.0603 | 1 | 1 |
Plasmodium falciparum | tubulin delta chain, putative | 0.0155 | 0.2353 | 0.2353 |
Leishmania major | cysteine peptidase A (CPA) | 0.002 | 0.0029 | 0.0029 |
Brugia malayi | Cathepsin L-like precursor | 0.002 | 0.0029 | 0.0029 |
Trichomonas vaginalis | tubulin alpha chain, putative | 0.0339 | 0.5493 | 0.548 |
Entamoeba histolytica | hypothetical protein | 0.0041 | 0.0389 | 0.0361 |
Leishmania major | beta tubulin | 0.0603 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.002 | 0.0029 | 0.0029 |
Trichomonas vaginalis | tubulin alpha chain, putative | 0.0603 | 1 | 1 |
Trichomonas vaginalis | tubulin beta-1 chain, putative | 0.0155 | 0.2353 | 0.2331 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0074 | 0.0966 | 0.0966 |
Echinococcus granulosus | tubulin alpha chain | 0.0454 | 0.7462 | 0.7462 |
Echinococcus granulosus | alpha tubulin | 0.0454 | 0.7462 | 0.7462 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0074 | 0.0966 | 0.0966 |
Trypanosoma cruzi | zeta tubulin, putative | 0.0481 | 0.7911 | 0.7911 |
Echinococcus granulosus | tubulin alpha chain | 0.0454 | 0.7462 | 0.7462 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.0454 | 0.7462 | 0.7455 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.002 | 0.0029 | 0.0029 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0074 | 0.0966 | 0.0966 |
Leishmania major | epsilon tubulin, putative | 0.037 | 0.6023 | 0.6023 |
Leishmania major | beta tubulin | 0.0603 | 1 | 1 |
Schistosoma mansoni | tubulin subunit delta | 0.0155 | 0.2353 | 0.2353 |
Leishmania major | beta tubulin | 0.0603 | 1 | 1 |
Schistosoma mansoni | tubulin subunit alpha | 0.0454 | 0.7462 | 0.7462 |
Leishmania major | beta tubulin | 0.0603 | 1 | 1 |
Trypanosoma cruzi | epsilon tubulin, putative | 0.037 | 0.6023 | 0.6023 |
Trypanosoma brucei | alpha tubulin | 0.0454 | 0.7462 | 0.7462 |
Loa Loa (eye worm) | tubulin beta-1 chain | 0.0603 | 1 | 1 |
Leishmania major | beta tubulin | 0.0603 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0074 | 0.0966 | 0.0966 |
Loa Loa (eye worm) | hypothetical protein | 0.0299 | 0.4804 | 0.4804 |
Toxoplasma gondii | tubulin/FtsZ family, GTPase domain-containing protein | 0.0339 | 0.5493 | 0.5493 |
Plasmodium falciparum | tubulin beta chain | 0.0603 | 1 | 1 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.0184 | 0.2834 | 0.2814 |
Echinococcus multilocularis | tubulin alpha chain | 0.0454 | 0.7462 | 0.7462 |
Trichomonas vaginalis | tubulin epsilon chain, putative | 0.0454 | 0.7462 | 0.7455 |
Entamoeba histolytica | tubulin family protein | 0.0603 | 1 | 1 |
Trichomonas vaginalis | tubulin, putative | 0.0603 | 1 | 1 |
Trichomonas vaginalis | tubulin alpha-1 chain, putative | 0.0454 | 0.7462 | 0.7455 |
Trichomonas vaginalis | tubulin alpha-1 chain, putative | 0.0271 | 0.4323 | 0.4307 |
Trichomonas vaginalis | tubulin epsilon chain, putative | 0.0454 | 0.7462 | 0.7455 |
Leishmania major | cathepsin L-like protease | 0.0074 | 0.0966 | 0.0966 |
Echinococcus granulosus | tubulin subunit TubB | 0.0454 | 0.7462 | 0.7462 |
Echinococcus granulosus | tubulin delta chain | 0.0155 | 0.2353 | 0.2353 |
Brugia malayi | Tubulin beta chain | 0.0155 | 0.2353 | 0.2353 |
Brugia malayi | Papain family cysteine protease containing protein | 0.002 | 0.0029 | 0.0029 |
Trypanosoma cruzi | beta tubulin, putative | 0.0603 | 1 | 1 |
Leishmania major | beta tubulin | 0.0603 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0068 | 0.0856 | 0.0856 |
Brugia malayi | Tubulin beta chain | 0.0184 | 0.2834 | 0.2834 |
Echinococcus granulosus | cathepsin l1 | 0.002 | 0.0029 | 0.0029 |
Echinococcus multilocularis | Tubulin alpha 1 chain | 0.0454 | 0.7462 | 0.7462 |
Toxoplasma gondii | beta-1 tubulin, putative | 0.0603 | 1 | 1 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0041 | 0.0389 | 0.0389 |
Leishmania major | cathepsin L-like protease | 0.0074 | 0.0966 | 0.0966 |
Leishmania major | beta tubulin | 0.0603 | 1 | 1 |
Schistosoma mansoni | alpha tubulin | 0.0454 | 0.7462 | 0.7462 |
Plasmodium vivax | vivapain-2 | 0.002 | 0.0029 | 0.0029 |
Plasmodium vivax | tubulin epsilon chain, putative | 0.037 | 0.6023 | 0.6023 |
Leishmania major | cathepsin L-like protease | 0.002 | 0.0029 | 0.0029 |
Schistosoma mansoni | single-minded | 0.0057 | 0.0664 | 0.0664 |
Brugia malayi | follicle stimulating hormone receptor | 0.027 | 0.4309 | 0.4309 |
Trichomonas vaginalis | tubulin epsilon chain, putative | 0.0155 | 0.2353 | 0.2331 |
Echinococcus multilocularis | tubulin epsilon chain | 0.037 | 0.6023 | 0.6023 |
Echinococcus granulosus | tubulin alpha 3 chain | 0.0454 | 0.7462 | 0.7462 |
Echinococcus granulosus | beta tubulin | 0.0603 | 1 | 1 |
Echinococcus granulosus | tubulin alpha chain | 0.0454 | 0.7462 | 0.7462 |
Echinococcus granulosus | Tubulin beta 2C chain | 0.0603 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0074 | 0.0966 | 0.0966 |
Leishmania major | gamma-tubulin | 0.0371 | 0.6031 | 0.6031 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.0454 | 0.7462 | 0.7455 |
Brugia malayi | Tubulin alpha chain | 0.0155 | 0.2353 | 0.2353 |
Giardia lamblia | Beta tubulin | 0.0603 | 1 | 1 |
Trypanosoma brucei | alpha tubulin, putative | 0.0184 | 0.2834 | 0.2834 |
Trichomonas vaginalis | tubulin alpha chain, putative | 0.0184 | 0.2834 | 0.2814 |
Entamoeba histolytica | tubulin family protein | 0.0603 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.002 | 0.0029 | 0.0029 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.002 | 0.0029 | 0.0029 |
Brugia malayi | Tubulin alpha-2 chain | 0.0454 | 0.7462 | 0.7462 |
Leishmania major | beta tubulin | 0.0603 | 1 | 1 |
Echinococcus granulosus | beta tubulin | 0.0603 | 1 | 1 |
Trichomonas vaginalis | tubulin epsilon chain, putative | 0.0603 | 1 | 1 |
Echinococcus granulosus | tubulin alpha 1C chain | 0.0454 | 0.7462 | 0.7462 |
Loa Loa (eye worm) | tubulin alpha 2 | 0.0299 | 0.4804 | 0.4804 |
Treponema pallidum | cell division protein FtsZ | 0.0155 | 0.2353 | 0.5 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0041 | 0.0389 | 0.0389 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.027 | 0.4309 | 0.4309 |
Loa Loa (eye worm) | tubulin beta chain | 0.0155 | 0.2353 | 0.2353 |
Leishmania major | beta tubulin | 0.0603 | 1 | 1 |
Trypanosoma cruzi | tubulin delta chain | 0.035 | 0.5678 | 0.5678 |
Echinococcus multilocularis | Tubulin beta 2C chain | 0.0603 | 1 | 1 |
Echinococcus multilocularis | Tubulin alpha 1 chain | 0.0454 | 0.7462 | 0.7462 |
Toxoplasma gondii | alpha tubulin TUBA1 | 0.0454 | 0.7462 | 0.7462 |
Echinococcus multilocularis | tubulin alpha | 0.0339 | 0.5493 | 0.5493 |
Echinococcus multilocularis | tubulin alpha chain | 0.0454 | 0.7462 | 0.7462 |
Echinococcus multilocularis | tubulin alpha chain | 0.0454 | 0.7462 | 0.7462 |
Echinococcus multilocularis | tubulin alpha 3 chain | 0.0454 | 0.7462 | 0.7462 |
Giardia lamblia | Alpha-tubulin | 0.0454 | 0.7462 | 0.6681 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.002 | 0.0029 | 0.0029 |
Toxoplasma gondii | beta tubulin | 0.0603 | 1 | 1 |
Trichomonas vaginalis | tubulin, putative | 0.0187 | 0.2892 | 0.2871 |
Echinococcus multilocularis | cysteine protease | 0.002 | 0.0029 | 0.0029 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.002 | 0.0029 | 0.0029 |
Echinococcus granulosus | peroxisome assembly protein 26 | 0.0454 | 0.7462 | 0.7462 |
Loa Loa (eye worm) | fibroinase | 0.002 | 0.0029 | 0.0029 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0155 | 0.2353 | 0.2331 |
Loa Loa (eye worm) | tubulin alpha 2 | 0.0299 | 0.4804 | 0.4804 |
Echinococcus granulosus | Tubulin beta 2C chain | 0.0603 | 1 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.002 | 0.0029 | 0.0029 |
Trypanosoma cruzi | tubulin delta chain | 0.035 | 0.5678 | 0.5678 |
Brugia malayi | Cytochrome P450 family protein | 0.003 | 0.0216 | 0.0216 |
Toxoplasma gondii | tubulin/FtsZ family, GTPase domain-containing protein | 0.035 | 0.5678 | 0.5678 |
Plasmodium vivax | tubulin gamma chain, putative | 0.0371 | 0.6031 | 0.6031 |
Loa Loa (eye worm) | tubulin alpha-3 chain | 0.0271 | 0.4323 | 0.4323 |
Brugia malayi | Tubulin gamma chain | 0.0371 | 0.6031 | 0.6031 |
Echinococcus multilocularis | Tubulin alpha 1 chain | 0.0454 | 0.7462 | 0.7462 |
Onchocerca volvulus | 0.0184 | 0.2834 | 1 | |
Trichomonas vaginalis | tubulin alpha chain, putative | 0.0184 | 0.2834 | 0.2814 |
Loa Loa (eye worm) | alpha-tubulin | 0.0454 | 0.7462 | 0.7462 |
Entamoeba histolytica | tubulin alpha chain, putative | 0.0454 | 0.7462 | 0.7455 |
Trichomonas vaginalis | tubulin gamma chain, putative | 0.037 | 0.6023 | 0.6011 |
Trichomonas vaginalis | tubulin, putative | 0.0184 | 0.2834 | 0.2814 |
Echinococcus granulosus | tubulin alpha chain | 0.0454 | 0.7462 | 0.7462 |
Echinococcus multilocularis | tubulin delta chain | 0.0155 | 0.2353 | 0.2353 |
Echinococcus multilocularis | tubulin subunit TubB | 0.0454 | 0.7462 | 0.7462 |
Brugia malayi | Cathepsin L-like precursor | 0.002 | 0.0029 | 0.0029 |
Leishmania major | beta tubulin | 0.0603 | 1 | 1 |
Echinococcus granulosus | tubulin epsilon chain | 0.037 | 0.6023 | 0.6023 |
Trypanosoma brucei | beta tubulin | 0.0603 | 1 | 1 |
Leishmania major | beta tubulin | 0.0603 | 1 | 1 |
Trypanosoma cruzi | zeta tubulin, putative | 0.0481 | 0.7911 | 0.7911 |
Leishmania major | delta tubulin, putative | 0.035 | 0.5678 | 0.5678 |
Plasmodium falciparum | alpha tubulin 2 | 0.0454 | 0.7462 | 0.7462 |
Brugia malayi | tubulin alpha-2 chain | 0.0454 | 0.7462 | 0.7462 |
Loa Loa (eye worm) | tubulin beta-4 chain | 0.0603 | 1 | 1 |
Echinococcus multilocularis | tubulin beta 1 chain | 0.0603 | 1 | 1 |
Mycobacterium ulcerans | cell division protein FtsZ | 0.0155 | 0.2353 | 1 |
Trypanosoma brucei | alpha tubulin | 0.0454 | 0.7462 | 0.7462 |
Mycobacterium leprae | cell division protein FtsZ | 0.0155 | 0.2353 | 0.5 |
Trypanosoma cruzi | alpha tubulin, putative | 0.0454 | 0.7462 | 0.7462 |
Trichomonas vaginalis | tubulin alpha chain, putative | 0.0184 | 0.2834 | 0.2814 |
Leishmania major | alpha tubulin | 0.0454 | 0.7462 | 0.7462 |
Leishmania major | alpha tubulin | 0.0454 | 0.7462 | 0.7462 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.0454 | 0.7462 | 0.7455 |
Echinococcus granulosus | tubulin beta 4A class IVa | 0.0603 | 1 | 1 |
Giardia lamblia | Beta tubulin | 0.0603 | 1 | 1 |
Brugia malayi | PAS domain containing protein | 0.0057 | 0.0664 | 0.0664 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0074 | 0.0966 | 0.0966 |
Echinococcus multilocularis | Tubulin beta 2C chain | 0.0603 | 1 | 1 |
Loa Loa (eye worm) | tubulin beta chain | 0.0603 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0041 | 0.0389 | 0.0361 |
Onchocerca volvulus | 0.0042 | 0.0413 | 0.1368 | |
Brugia malayi | alpha-tubulin | 0.0454 | 0.7462 | 0.7462 |
Echinococcus multilocularis | Tubulin beta 2C chain | 0.0603 | 1 | 1 |
Toxoplasma gondii | cathepsin CPL | 0.002 | 0.0029 | 0.0029 |
Schistosoma mansoni | tubulin subunit alpha | 0.0454 | 0.7462 | 0.7462 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.0454 | 0.7462 | 0.7455 |
Plasmodium falciparum | alpha tubulin 1 | 0.0454 | 0.7462 | 0.7462 |
Loa Loa (eye worm) | hypoxia-induced factor 1 | 0.0175 | 0.2695 | 0.2695 |
Leishmania major | alpha tubulin | 0.0454 | 0.7462 | 0.7462 |
Mycobacterium tuberculosis | Cell division protein FtsZ | 0.0155 | 0.2353 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0074 | 0.0966 | 0.0966 |
Echinococcus multilocularis | tubulin, beta 4A class IVa | 0.0603 | 1 | 1 |
Trypanosoma brucei | tubulin delta chain | 0.035 | 0.5678 | 0.5678 |
Echinococcus granulosus | tubulin gamma 1 chain | 0.0371 | 0.6031 | 0.6031 |
Trypanosoma brucei | zeta tubulin | 0.0481 | 0.7911 | 0.7911 |
Schistosoma mansoni | tubulin subunit beta | 0.0603 | 1 | 1 |
Trypanosoma cruzi | epsilon tubulin, putative | 0.037 | 0.6023 | 0.6023 |
Echinococcus granulosus | Tubulin beta 2C chain | 0.0603 | 1 | 1 |
Trypanosoma brucei | epsilon tubulin | 0.037 | 0.6023 | 0.6023 |
Schistosoma mansoni | tubulin subunit beta | 0.0603 | 1 | 1 |
Schistosoma mansoni | tubulin subunit gamma | 0.0371 | 0.6031 | 0.6031 |
Leishmania major | alpha tubulin | 0.0454 | 0.7462 | 0.7462 |
Schistosoma mansoni | tubulin subunit beta | 0.0155 | 0.2353 | 0.2353 |
Giardia lamblia | Beta tubulin | 0.0603 | 1 | 1 |
Entamoeba histolytica | tubulin gamma chain | 0.0371 | 0.6031 | 0.6019 |
Loa Loa (eye worm) | hypothetical protein | 0.0454 | 0.7462 | 0.7462 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.002 | 0.0029 | 0.0029 |
Wolbachia endosymbiont of Brugia malayi | cell division protein FtsZ | 0.0155 | 0.2353 | 0.5 |
Trypanosoma brucei | beta tubulin | 0.0603 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0074 | 0.0966 | 0.0966 |
Loa Loa (eye worm) | ctsf protein | 0.002 | 0.0029 | 0.0029 |
Echinococcus granulosus | Tubulin beta 2C chain | 0.0603 | 1 | 1 |
Loa Loa (eye worm) | tubulin alpha 2 | 0.0115 | 0.1665 | 0.1665 |
Loa Loa (eye worm) | hypothetical protein | 0.019 | 0.2947 | 0.2947 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0058 | 0.0694 | 0.0694 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0074 | 0.0966 | 0.0966 |
Schistosoma mansoni | tubulin subunit alpha | 0.0454 | 0.7462 | 0.7462 |
Trypanosoma brucei | epsilon tubulin | 0.0339 | 0.5493 | 0.5493 |
Entamoeba histolytica | tubulin alpha-1 chain | 0.0454 | 0.7462 | 0.7455 |
Echinococcus multilocularis | hypothetical protein | 0.0454 | 0.7462 | 0.7462 |
Leishmania major | beta tubulin | 0.0603 | 1 | 1 |
Loa Loa (eye worm) | beta-tubulin | 0.0603 | 1 | 1 |
Trichomonas vaginalis | tubulin, putative | 0.0184 | 0.2834 | 0.2814 |
Trichomonas vaginalis | tubulin alpha-1 chain, putative | 0.0299 | 0.4804 | 0.4789 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.002 | 0.0029 | 0.0029 |
Trichomonas vaginalis | tubulin gamma chain, putative | 0.0371 | 0.6031 | 0.6019 |
Brugia malayi | Cathepsin L-like precursor | 0.002 | 0.0029 | 0.0029 |
Loa Loa (eye worm) | hypothetical protein | 0.0271 | 0.4323 | 0.4323 |
Echinococcus multilocularis | cysteine protease | 0.002 | 0.0029 | 0.0029 |
Giardia lamblia | Epsilon tubulin | 0.0186 | 0.2884 | 0.0694 |
Trypanosoma brucei | epsilon tubulin | 0.037 | 0.6023 | 0.6023 |
Schistosoma mansoni | hypothetical protein | 0.0191 | 0.2964 | 0.2964 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0074 | 0.0966 | 0.0966 |
Leishmania major | beta tubulin | 0.0603 | 1 | 1 |
Echinococcus multilocularis | tubulin alpha 1C chain | 0.0454 | 0.7462 | 0.7462 |
Schistosoma mansoni | tubulin subunit beta | 0.0603 | 1 | 1 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.0454 | 0.7462 | 0.7455 |
Leishmania major | alpha tubulin | 0.0454 | 0.7462 | 0.7462 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0074 | 0.0966 | 0.0966 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0074 | 0.0966 | 0.0966 |
Loa Loa (eye worm) | alpha-tubulin isotype 2 | 0.0299 | 0.4804 | 0.4804 |
Echinococcus multilocularis | transfer RNA-Lys | 0.0042 | 0.0413 | 0.0413 |
Leishmania major | alpha tubulin | 0.0454 | 0.7462 | 0.7462 |
Leishmania major | alpha tubulin | 0.0454 | 0.7462 | 0.7462 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Diuretic activity (functional) | = 1.2 ml kg-1 | Diuretic activity in the rats, determined by a modified Lipschitz test | ChEMBL. | 6876086 |
Saluretic activity (functional) | = 0.3 m equiv 5hr-1 kg-1 | Saluretic activity in the rat measured as concentration of Na+ in urine | ChEMBL. | 6876086 |
Saluretic activity (functional) | = 0.7 m equiv 5hr-1 kg-1 | Saluretic activity in the rat measured as concentration of chloride in urine | ChEMBL. | 6876086 |
Saluretic activity (functional) | = 1.1 m equiv 5hr-1 kg-1 | Saluretic activity in the rat measured as concentration of K+ in urine | ChEMBL. | 6876086 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.