Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1205 | 0.3886 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0027 | 0.0027 |
Entamoeba histolytica | hypothetical protein | 0.0293 | 0.0921 | 0.2231 |
Echinococcus multilocularis | cathepsin L | 0.0293 | 0.0921 | 0.0921 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0663 | 0.2123 | 0.2123 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0027 | 0.0059 | 0.0059 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0018 | 0.0027 | 0.0027 |
Onchocerca volvulus | 0.1205 | 0.3886 | 1 | |
Schistosoma mansoni | cathepsin S (C01 family) | 0.0293 | 0.0921 | 0.0921 |
Brugia malayi | ecdysteroid receptor | 0.0018 | 0.0027 | 0.0027 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0018 | 0.0027 | 0.0027 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0018 | 0.0027 | 0.0027 |
Echinococcus multilocularis | smad | 0.0014 | 0.0016 | 0.0016 |
Entamoeba histolytica | cysteine protease, putative | 0.0293 | 0.0921 | 0.2231 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.1205 | 0.3886 | 0.386 |
Echinococcus multilocularis | cathepsin b | 0.3087 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0293 | 0.0921 | 0.0921 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1205 | 0.3886 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0293 | 0.0921 | 0.2231 |
Entamoeba histolytica | cysteine protease, putative | 0.0663 | 0.2123 | 0.538 |
Loa Loa (eye worm) | cysteine protease | 0.1205 | 0.3886 | 0.3886 |
Loa Loa (eye worm) | hypothetical protein | 0.0835 | 0.2684 | 0.2684 |
Echinococcus multilocularis | GPCR, family 2 | 0.0027 | 0.0059 | 0.0059 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.1157 | 0.3729 | 0.9593 |
Schistosoma mansoni | hypothetical protein | 0.0027 | 0.0059 | 0.0059 |
Schistosoma mansoni | hypothetical protein | 0.0027 | 0.0059 | 0.0059 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.1205 | 0.3886 | 0.3886 |
Onchocerca volvulus | 0.1205 | 0.3886 | 1 | |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0018 | 0.0027 | 0.0027 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0018 | 0.0027 | 0.0027 |
Schistosoma mansoni | subfamily C1A non-peptidase homologue (C01 family) | 0.0293 | 0.0921 | 0.0921 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1205 | 0.3886 | 0.386 |
Brugia malayi | Smad1 | 0.0014 | 0.0016 | 0.0016 |
Echinococcus granulosus | FTZ F1 alpha | 0.0018 | 0.0027 | 0.0027 |
Brugia malayi | hypothetical protein | 0.0014 | 0.0016 | 0.0016 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0293 | 0.0921 | 0.0921 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0042 | 0.0042 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0087 | 0.0252 | 0.0252 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.001 | 0.0004 | 0.0004 |
Echinococcus granulosus | cathepsin L | 0.0663 | 0.2123 | 0.2123 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0293 | 0.0921 | 0.0921 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0293 | 0.0921 | 0.0921 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0018 | 0.0027 | 0.0027 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.001 | 0.0002 | 0.0002 |
Brugia malayi | cathepsin Z-like cysteine proteinase | 0.0293 | 0.0921 | 0.0921 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0027 | 0.0027 |
Loa Loa (eye worm) | fibroinase | 0.1205 | 0.3886 | 0.3886 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0018 | 0.0027 | 0.0027 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.3087 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0663 | 0.2123 | 0.538 |
Entamoeba histolytica | cysteine protease, putative | 0.0663 | 0.2123 | 0.538 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0018 | 0.0027 | 0.0027 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0663 | 0.2123 | 0.538 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0293 | 0.0921 | 0.0883 |
Schistosoma mansoni | cpg binding protein | 0.0036 | 0.0086 | 0.0086 |
Loa Loa (eye worm) | hypothetical protein | 0.037 | 0.1172 | 0.1172 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0018 | 0.0027 | 0.0027 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0031 | 0.007 | 0.007 |
Plasmodium vivax | dipeptidyl aminopeptidase 1, putative | 0.0293 | 0.0921 | 0.2288 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0293 | 0.0921 | 0.0921 |
Echinococcus granulosus | Smad4 | 0.0014 | 0.0016 | 0.0016 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.1205 | 0.3886 | 0.3886 |
Onchocerca volvulus | Cathepsin L homolog | 0.1205 | 0.3886 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.1205 | 0.3886 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0293 | 0.0921 | 0.0921 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1205 | 0.3886 | 1 |
Brugia malayi | nuclear receptor NHR-88 | 0.0018 | 0.0027 | 0.0027 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0018 | 0.0027 | 0.0027 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.3087 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1205 | 0.3886 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0146 | 0.0443 | 0.0443 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0072 | 0.0202 | 0.0202 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0835 | 0.2684 | 0.2653 |
Onchocerca volvulus | Cathepsin L homolog | 0.1205 | 0.3886 | 1 |
Brugia malayi | hypothetical protein | 0.0031 | 0.007 | 0.007 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.1205 | 0.3886 | 1 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.037 | 0.1172 | 0.1172 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0663 | 0.2123 | 0.5414 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0018 | 0.0027 | 0.0027 |
Entamoeba histolytica | cysteine protease, putative | 0.0293 | 0.0921 | 0.2231 |
Leishmania major | cathepsin L-like protease | 0.1205 | 0.3886 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0835 | 0.2684 | 0.685 |
Entamoeba histolytica | cysteine protease, putative | 0.0293 | 0.0921 | 0.2231 |
Leishmania major | cathepsin L-like protease | 0.1205 | 0.3886 | 1 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0014 | 0.0016 | 0.0016 |
Echinococcus multilocularis | cpg binding protein | 0.0036 | 0.0086 | 0.0086 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.1205 | 0.3886 | 0.3886 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0018 | 0.0027 | 0.0027 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.1157 | 0.3729 | 0.9593 |
Brugia malayi | cathepsin Z-like cysteine proteinase | 0.0293 | 0.0921 | 0.0921 |
Entamoeba histolytica | cysteine protease, putative | 0.0663 | 0.2123 | 0.538 |
Brugia malayi | MH2 domain containing protein | 0.0208 | 0.0645 | 0.0645 |
Echinococcus multilocularis | geminin | 0.0146 | 0.0443 | 0.0443 |
Plasmodium vivax | serine-repeat antigen (SERA) | 0.0293 | 0.0921 | 0.2288 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0018 | 0.0027 | 0.0027 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Plasmodium falciparum | serine repeat antigen 9 | 0.0293 | 0.0921 | 0.2288 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0027 | 0.0027 |
Entamoeba histolytica | cysteine protease, putative | 0.0293 | 0.0921 | 0.2231 |
Schistosoma mansoni | dipeptidyl-peptidase I (C01 family) | 0.0293 | 0.0921 | 0.0921 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.1157 | 0.3729 | 0.3703 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0018 | 0.0027 | 0.0027 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0027 | 0.0027 |
Loa Loa (eye worm) | ctsf protein | 0.1205 | 0.3886 | 0.3886 |
Plasmodium falciparum | serine repeat antigen 4 | 0.0293 | 0.0921 | 0.2288 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0018 | 0.0027 | 0.0027 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.001 | 0.0002 | 0.0002 |
Plasmodium vivax | serine-repeat antigen 4 (SERA), putative | 0.0293 | 0.0921 | 0.2288 |
Echinococcus multilocularis | cysteine protease | 0.1205 | 0.3886 | 0.3886 |
Onchocerca volvulus | Cathepsin L homolog | 0.0293 | 0.0921 | 0.2318 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Plasmodium vivax | vivapain-1 | 0.0663 | 0.2123 | 0.5414 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0018 | 0.0027 | 0.0027 |
Echinococcus granulosus | GPCR family 2 | 0.0027 | 0.0059 | 0.0059 |
Schistosoma mansoni | cpg binding protein | 0.0036 | 0.0086 | 0.0086 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0059 | 0.0163 | 0.0163 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0663 | 0.2123 | 0.2123 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.001 | 0.0004 | 0.0004 |
Toxoplasma gondii | cathepsin CPL | 0.1205 | 0.3886 | 1 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.0663 | 0.2123 | 0.2123 |
Toxoplasma gondii | cathepsin CPC2 | 0.0293 | 0.0921 | 0.2288 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0027 | 0.0059 | 0.0059 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1205 | 0.3886 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.1157 | 0.3729 | 1 |
Plasmodium vivax | vivapain-2 | 0.1205 | 0.3886 | 1 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0018 | 0.0027 | 0.0027 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0027 | 0.0059 | 0.0059 |
Brugia malayi | nuclear hormone receptor | 0.0018 | 0.0027 | 0.0027 |
Schistosoma mansoni | smad1 5 8 and | 0.0014 | 0.0016 | 0.0016 |
Plasmodium falciparum | serine repeat antigen 8 | 0.0293 | 0.0921 | 0.2288 |
Echinococcus granulosus | cathepsin b | 0.3087 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0663 | 0.2123 | 0.2123 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Entamoeba histolytica | papain family cysteine protease domain containing protein | 0.0293 | 0.0921 | 0.2231 |
Plasmodium vivax | vivapain-2 | 0.1205 | 0.3886 | 1 |
Onchocerca volvulus | 0.0293 | 0.0921 | 0.2318 | |
Entamoeba histolytica | cysteine proteinase 1, putative | 0.0663 | 0.2123 | 0.538 |
Entamoeba histolytica | cysteine protease, putative | 0.0663 | 0.2123 | 0.538 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1205 | 0.3886 | 1 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0208 | 0.0645 | 0.0645 |
Plasmodium falciparum | serine repeat antigen 5 | 0.0293 | 0.0921 | 0.2288 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0835 | 0.2684 | 0.5946 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0663 | 0.2123 | 0.209 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0018 | 0.0027 | 0.0027 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0018 | 0.0027 | 0.0027 |
Toxoplasma gondii | preprocathepsin c precursor, putative | 0.0293 | 0.0921 | 0.2288 |
Echinococcus granulosus | smad | 0.0014 | 0.0016 | 0.0016 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0293 | 0.0921 | 0.0921 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1205 | 0.3886 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0663 | 0.2123 | 0.538 |
Trypanosoma cruzi | cysteine protease, putative | 0.0663 | 0.2123 | 0.209 |
Schistosoma mansoni | smad1 5 8 and | 0.0014 | 0.0016 | 0.0016 |
Schistosoma mansoni | cathepsin C | 0.0293 | 0.0921 | 0.0921 |
Leishmania major | cathepsin L-like protease | 0.1205 | 0.3886 | 1 |
Plasmodium vivax | unspecified product | 0.0293 | 0.0921 | 0.2288 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.007 | 0.007 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0018 | 0.0027 | 0.0027 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0018 | 0.0027 | 0.0027 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.1205 | 0.3886 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.1205 | 0.3886 | 0.3886 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0059 | 0.0059 |
Schistosoma mansoni | nuclear hormone receptor | 0.0018 | 0.0027 | 0.0027 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0018 | 0.0027 | 0.0027 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0018 | 0.0027 | 0.0027 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0014 | 0.0016 | 0.0016 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.1157 | 0.3729 | 0.9472 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0293 | 0.0921 | 0.0921 |
Onchocerca volvulus | 0.0835 | 0.2684 | 0.6886 | |
Schistosoma mansoni | cathepsin B (C01 family) | 0.0293 | 0.0921 | 0.0921 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0018 | 0.0027 | 0.0027 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0018 | 0.0027 | 0.0027 |
Echinococcus granulosus | cathepsin l1 | 0.1205 | 0.3886 | 0.3886 |
Brugia malayi | Cathepsin L-like precursor | 0.0835 | 0.2684 | 0.2684 |
Brugia malayi | hypothetical protein | 0.0022 | 0.0042 | 0.0042 |
Loa Loa (eye worm) | hypothetical protein | 0.0293 | 0.0921 | 0.0921 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0018 | 0.0027 | 0.0027 |
Plasmodium vivax | vivapain-3 | 0.0663 | 0.2123 | 0.5414 |
Brugia malayi | cathepsin L-like cysteine proteinase, identical | 0.037 | 0.1172 | 0.1172 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.1205 | 0.3886 | 0.3886 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0018 | 0.0027 | 0.0027 |
Schistosoma mansoni | hypothetical protein | 0.0146 | 0.0443 | 0.0443 |
Leishmania major | cathepsin L-like protease | 0.1205 | 0.3886 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.037 | 0.1172 | 0.1172 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0663 | 0.2123 | 0.2123 |
Entamoeba histolytica | cysteine protease, putative | 0.0663 | 0.2123 | 0.538 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0018 | 0.0027 | 0.0027 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0018 | 0.0027 | 0.0027 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0293 | 0.0921 | 0.0921 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1205 | 0.3886 | 0.386 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0064 | 0.0178 | 0.0353 |
Schistosoma mansoni | Smad4 | 0.0014 | 0.0016 | 0.0016 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0663 | 0.2123 | 0.538 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.0293 | 0.0921 | 0.0921 |
Brugia malayi | Cathepsin L-like precursor | 0.1205 | 0.3886 | 0.3886 |
Echinococcus multilocularis | cathepsin b | 0.3087 | 1 | 1 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0014 | 0.0016 | 0.0016 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0087 | 0.0252 | 0.0252 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.0663 | 0.2123 | 0.209 |
Echinococcus multilocularis | cathepsin L | 0.0663 | 0.2123 | 0.2123 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0034 | 0.008 | 0.008 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0018 | 0.0027 | 0.0027 |
Brugia malayi | cathepsin L-like cysteine proteinase | 0.0293 | 0.0921 | 0.0921 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.001 | 0.0003 | 0.0003 |
Plasmodium falciparum | cysteine proteinase falcipain 1 | 0.0663 | 0.2123 | 0.5414 |
Leishmania major | cathepsin L-like protease | 0.1205 | 0.3886 | 1 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0018 | 0.0027 | 0.0027 |
Plasmodium vivax | dipeptidyl aminopeptidase 2, putative | 0.0293 | 0.0921 | 0.2288 |
Entamoeba histolytica | papain family cysteine protease domain containing protein | 0.0293 | 0.0921 | 0.2231 |
Onchocerca volvulus | Cathepsin F homolog | 0.1205 | 0.3886 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.3087 | 1 | 1 |
Loa Loa (eye worm) | Smad1 | 0.0014 | 0.0016 | 0.0016 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1205 | 0.3886 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0293 | 0.0921 | 0.0921 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0087 | 0.0252 | 0.0252 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0018 | 0.0027 | 0.0027 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0018 | 0.0027 | 0.0027 |
Entamoeba histolytica | cysteine protease, putative | 0.0663 | 0.2123 | 0.538 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0018 | 0.0027 | 0.0027 |
Schistosoma mansoni | neuropeptide receptor | 0.0216 | 0.0673 | 0.0673 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0835 | 0.2684 | 0.2684 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Brugia malayi | cahepsin L-like non-peptiedase homolog | 0.0293 | 0.0921 | 0.0921 |
Entamoeba histolytica | cysteine protease, putative | 0.0293 | 0.0921 | 0.2231 |
Brugia malayi | Cathepsin L-like precursor | 0.1205 | 0.3886 | 0.3886 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0018 | 0.0027 | 0.0027 |
Brugia malayi | CXXC zinc finger family protein | 0.0034 | 0.008 | 0.008 |
Schistosoma mansoni | hypothetical protein | 0.001 | 0.0002 | 0.0002 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0027 | 0.0027 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0018 | 0.0027 | 0.0027 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0018 | 0.0027 | 0.0027 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0835 | 0.2684 | 0.2684 |
Schistosoma mansoni | smad1 5 8 and | 0.0014 | 0.0016 | 0.0016 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0216 | 0.0673 | 0.0673 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.1205 | 0.3886 | 0.3886 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0208 | 0.0645 | 0.0645 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1205 | 0.3886 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0018 | 0.0027 | 0.0027 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1205 | 0.3886 | 1 |
Echinococcus multilocularis | neuropeptide receptor | 0.0216 | 0.0673 | 0.0673 |
Leishmania major | cysteine peptidase A (CPA) | 0.1205 | 0.3886 | 1 |
Loa Loa (eye worm) | cysteine proteinase cathepsin Z | 0.0293 | 0.0921 | 0.0921 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.3087 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0293 | 0.0921 | 0.0921 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0018 | 0.0027 | 0.0027 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0014 | 0.0016 | 0.0016 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1205 | 0.3886 | 0.386 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0027 | 0.0059 | 0.0059 |
Brugia malayi | Cathepsin L-like precursor | 0.1205 | 0.3886 | 0.3886 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.1205 | 0.3886 | 0.3886 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0293 | 0.0921 | 0.0921 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0663 | 0.2123 | 0.4054 |
Plasmodium vivax | serine-repeat antigen (SERA) | 0.0293 | 0.0921 | 0.2288 |
Brugia malayi | Cathepsin L-like precursor | 0.1205 | 0.3886 | 0.3886 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0027 | 0.0027 |
Plasmodium falciparum | serine repeat antigen 3 | 0.0293 | 0.0921 | 0.2288 |
Plasmodium vivax | serine-repeat antigen (SERA), putative | 0.0293 | 0.0921 | 0.2288 |
Entamoeba histolytica | cysteine proteinase 2 | 0.0663 | 0.2123 | 0.538 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0018 | 0.0027 | 0.0027 |
Leishmania major | cathepsin L-like protease | 0.1205 | 0.3886 | 1 |
Echinococcus multilocularis | cysteine protease | 0.1205 | 0.3886 | 0.3886 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0014 | 0.0016 | 0.0016 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0663 | 0.2123 | 0.2123 |
Onchocerca volvulus | 0.1205 | 0.3886 | 1 | |
Brugia malayi | Cathepsin L-like precursor | 0.037 | 0.1172 | 0.1172 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0018 | 0.0027 | 0.0027 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1205 | 0.3886 | 1 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0481 | 0.1532 | 0.1532 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0663 | 0.2123 | 0.209 |
Echinococcus granulosus | cpg binding protein | 0.0036 | 0.0086 | 0.0086 |
Schistosoma mansoni | smad | 0.0014 | 0.0016 | 0.0016 |
Plasmodium vivax | serine-repeat antigen 4 (SERA) | 0.0293 | 0.0921 | 0.2288 |
Onchocerca volvulus | 0.0034 | 0.008 | 0.0136 | |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.1205 | 0.3886 | 0.3886 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1205 | 0.3886 | 0.386 |
Giardia lamblia | Cathepsin B precursor | 0.1157 | 0.3729 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0027 | 0.0027 |
Echinococcus granulosus | cysteine protease | 0.0663 | 0.2123 | 0.2123 |
Entamoeba histolytica | cysteine protease, putative | 0.0663 | 0.2123 | 0.538 |
Echinococcus granulosus | neuropeptide receptor | 0.0216 | 0.0673 | 0.0673 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0663 | 0.2123 | 0.209 |
Onchocerca volvulus | 0.1205 | 0.3886 | 1 | |
Plasmodium falciparum | serine repeat antigen 6 | 0.0293 | 0.0921 | 0.2288 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0663 | 0.2123 | 0.538 |
Plasmodium falciparum | dipeptidyl aminopeptidase 3 | 0.0293 | 0.0921 | 0.2288 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.1205 | 0.3886 | 0.3886 |
Brugia malayi | MH2 domain containing protein | 0.0014 | 0.0016 | 0.0016 |
Loa Loa (eye worm) | hypothetical protein | 0.0293 | 0.0921 | 0.0921 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.3087 | 1 | 1 |
Onchocerca volvulus | 0.1205 | 0.3886 | 1 | |
Plasmodium falciparum | dipeptidyl aminopeptidase 1 | 0.0293 | 0.0921 | 0.2288 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0663 | 0.2123 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Plasmodium falciparum | serine repeat antigen 2 | 0.0293 | 0.0921 | 0.2288 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0018 | 0.0027 | 0.0027 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0293 | 0.0921 | 0.0883 |
Echinococcus multilocularis | Smad4 | 0.0014 | 0.0016 | 0.0016 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0018 | 0.0027 | 0.0027 |
Entamoeba histolytica | cysteine protease, putative | 0.0663 | 0.2123 | 0.538 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0031 | 0.007 | 0.007 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.037 | 0.1172 | 0.1134 |
Brugia malayi | MH1 domain containing protein | 0.0014 | 0.0016 | 0.0016 |
Schistosoma mansoni | cathepsin s | 0.037 | 0.1172 | 0.1172 |
Plasmodium falciparum | dipeptidyl aminopeptidase 2 | 0.0293 | 0.0921 | 0.2288 |
Leishmania major | cathepsin L-like protease | 0.1205 | 0.3886 | 1 |
Plasmodium vivax | unspecified product | 0.037 | 0.1172 | 0.2939 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0018 | 0.0027 | 0.0027 |
Schistosoma mansoni | hypothetical protein | 0.0481 | 0.1532 | 0.1532 |
Brugia malayi | steroid hormone receptor | 0.0018 | 0.0027 | 0.0027 |
Entamoeba histolytica | cysteine protease, putative | 0.0663 | 0.2123 | 0.538 |
Loa Loa (eye worm) | hypothetical protein | 0.037 | 0.1172 | 0.1172 |
Echinococcus granulosus | cathepsin b | 0.3087 | 1 | 1 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0014 | 0.0016 | 0.0016 |
Loa Loa (eye worm) | hypothetical protein | 0.1205 | 0.3886 | 0.3886 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0018 | 0.0027 | 0.0027 |
Onchocerca volvulus | 0.1205 | 0.3886 | 1 | |
Schistosoma mansoni | hypothetical protein | 0.0059 | 0.0163 | 0.0163 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0027 | 0.0027 |
Brugia malayi | Papain family cysteine protease containing protein | 0.1205 | 0.3886 | 0.3886 |
Brugia malayi | Cathepsin L-like precursor | 0.1205 | 0.3886 | 0.3886 |
Brugia malayi | Cathepsin L-like precursor | 0.0835 | 0.2684 | 0.2684 |
Giardia lamblia | Cathepsin B precursor | 0.1157 | 0.3729 | 1 |
Schistosoma mansoni | subfamily C1A unassigned peptidase (C01 family) | 0.0293 | 0.0921 | 0.0921 |
Schistosoma mansoni | subfamily C1A unassigned peptidase (C01 family) | 0.0293 | 0.0921 | 0.0921 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0018 | 0.0027 | 0.0027 |
Schistosoma mansoni | hypothetical protein | 0.0027 | 0.0059 | 0.0059 |
Brugia malayi | Cathepsin L-like precursor | 0.1205 | 0.3886 | 0.3886 |
Plasmodium vivax | unspecified product | 0.0663 | 0.2123 | 0.5414 |
Loa Loa (eye worm) | hypothetical protein | 0.0835 | 0.2684 | 0.2684 |
Brugia malayi | cathepsin L-like precursor | 0.0835 | 0.2684 | 0.2684 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.0163 | 0.0163 |
Onchocerca volvulus | 0.1205 | 0.3886 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1205 | 0.3886 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.0252 | 0.0252 |
Leishmania major | cathepsin L-like protease | 0.1205 | 0.3886 | 1 |
Echinococcus granulosus | dnaJ subfamily B | 0.0481 | 0.1532 | 0.1532 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0027 | 0.0059 | 0.0059 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1157 | 0.3729 | 0.3729 |
Plasmodium vivax | serine-repeat antigen (SERA), putative | 0.0293 | 0.0921 | 0.2288 |
Schistosoma mansoni | hypothetical protein | 0.0027 | 0.0059 | 0.0059 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1205 | 0.3886 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0018 | 0.0027 | 0.0027 |
Brugia malayi | MH2 domain containing protein | 0.0014 | 0.0016 | 0.0016 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.1205 | 0.3886 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0663 | 0.2123 | 0.538 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.037 | 0.1172 | 0.1134 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0014 | 0.0016 | 0.0016 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Echinococcus granulosus | cathepsin L | 0.0293 | 0.0921 | 0.0921 |
Plasmodium vivax | serine-repeat antigen 5 (SERA) | 0.0293 | 0.0921 | 0.2288 |
Schistosoma mansoni | coup transcription factor | 0.0018 | 0.0027 | 0.0027 |
Loa Loa (eye worm) | hypothetical protein | 0.0293 | 0.0921 | 0.0921 |
Echinococcus granulosus | geminin | 0.0146 | 0.0443 | 0.0443 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.1205 | 0.3886 | 0.3886 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.037 | 0.1172 | 0.1172 |
Loa Loa (eye worm) | hypothetical protein | 0.0835 | 0.2684 | 0.2684 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0663 | 0.2123 | 0.5414 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0027 | 0.0059 | 0.0059 |
Plasmodium vivax | dipeptidyl aminopeptidase 3, putative | 0.0293 | 0.0921 | 0.2288 |
Toxoplasma gondii | cathepsin B | 0.1157 | 0.3729 | 0.9593 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0018 | 0.0027 | 0.0027 |
Brugia malayi | fibroinase precursor | 0.0293 | 0.0921 | 0.0921 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0663 | 0.2123 | 0.538 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0031 | 0.007 | 0.007 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Plasmodium vivax | serine-repeat antigen 3 (SERA) | 0.0293 | 0.0921 | 0.2288 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0018 | 0.0027 | 0.0027 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0018 | 0.0027 | 0.0027 |
Toxoplasma gondii | cathepsin CPC1 | 0.0293 | 0.0921 | 0.2288 |
Loa Loa (eye worm) | hypothetical protein | 0.3087 | 1 | 1 |
Plasmodium falciparum | serine repeat antigen 1 | 0.0293 | 0.0921 | 0.2288 |
Plasmodium vivax | serine-repeat antigen 2 (SERA) | 0.0293 | 0.0921 | 0.2288 |
Echinococcus granulosus | cathepsin l1 | 0.0835 | 0.2684 | 0.2684 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0018 | 0.0027 | 0.0027 |
Loa Loa (eye worm) | histone methyltransferase | 0.001 | 0.0004 | 0.0004 |
Brugia malayi | MH1 domain containing protein | 0.0014 | 0.0016 | 0.0016 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0027 | 0.0059 | 0.0059 |
Plasmodium falciparum | serine repeat antigen 7 | 0.0293 | 0.0921 | 0.2288 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0835 | 0.2684 | 0.5946 |
Loa Loa (eye worm) | cathepsin B | 0.1157 | 0.3729 | 0.3729 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0663 | 0.2123 | 0.538 |
Schistosoma mansoni | cpg binding protein | 0.0034 | 0.008 | 0.008 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0018 | 0.0027 | 0.0027 |
Brugia malayi | cathepsin L precursor | 0.0293 | 0.0921 | 0.0921 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0293 | 0.0921 | 0.0921 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
ED50 (functional) | = 12 mg kg-1 | Antiwrithing activity in sc dosed mouse assessed as prevention of acetylcholine-induced abdominal constriction response | ChEMBL. | 31481 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.