Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | cathepsin L-like protease | 0.0318 | 0.4176 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0218 | 0.1329 | 0.0228 |
Onchocerca volvulus | Cathepsin L homolog | 0.0318 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0318 | 0.4176 | 1 |
Echinococcus multilocularis | cathepsin b | 0.0524 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0318 | 0.4176 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0318 | 0.4176 | 0.4176 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0318 | 0.4176 | 0.4176 |
Leishmania major | cathepsin L-like protease | 0.0318 | 0.4176 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0318 | 0.4176 | 0.4176 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0211 | 0.1126 | 0.1126 |
Onchocerca volvulus | Cathepsin F homolog | 0.0318 | 0.4176 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0318 | 0.4176 | 0.4176 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0318 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0318 | 0.4176 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0318 | 0.4176 | 0.4176 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0318 | 0.4176 | 0.4176 |
Onchocerca volvulus | 0.0318 | 0.4176 | 1 | |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0318 | 0.4176 | 1 |
Leishmania major | cysteine peptidase A (CPA) | 0.0318 | 0.4176 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0318 | 0.4176 | 0.4176 |
Onchocerca volvulus | 0.0318 | 0.4176 | 1 | |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0318 | 0.4176 | 0.4176 |
Loa Loa (eye worm) | hypothetical protein | 0.0524 | 1 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0218 | 0.1329 | 0.1329 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0318 | 0.4176 | 1 |
Plasmodium vivax | vivapain-2 | 0.0318 | 0.4176 | 1 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0524 | 1 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0318 | 0.4176 | 0.4176 |
Leishmania major | cathepsin L-like protease | 0.0318 | 0.4176 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0218 | 0.1329 | 0.1329 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0318 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0318 | 0.4176 | 1 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0211 | 0.1126 | 0.2697 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0318 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0318 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0318 | 0.4176 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0211 | 0.1126 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0318 | 0.4176 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0318 | 0.4176 | 1 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0218 | 0.1329 | 0.1329 |
Loa Loa (eye worm) | cysteine protease | 0.0318 | 0.4176 | 0.3437 |
Toxoplasma gondii | cathepsin CPL | 0.0318 | 0.4176 | 1 |
Onchocerca volvulus | 0.0318 | 0.4176 | 1 | |
Leishmania major | cathepsin L-like protease | 0.0318 | 0.4176 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0318 | 0.4176 | 0.4176 |
Onchocerca volvulus | 0.0318 | 0.4176 | 1 | |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0318 | 0.4176 | 0.4176 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0318 | 0.4176 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0524 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0318 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0318 | 0.4176 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0318 | 0.4176 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0318 | 0.4176 | 0.4176 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0318 | 0.4176 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0318 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0318 | 0.4176 | 1 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0318 | 0.4176 | 0.4176 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0318 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0318 | 0.4176 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0524 | 1 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0211 | 0.1126 | 0.5 |
Echinococcus multilocularis | cathepsin b | 0.0524 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0524 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0318 | 0.4176 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0318 | 0.4176 | 0.3437 |
Echinococcus granulosus | cathepsin l1 | 0.0318 | 0.4176 | 0.4176 |
Brugia malayi | Cathepsin L-like precursor | 0.0218 | 0.1329 | 0.1329 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0318 | 0.4176 | 1 |
Leishmania major | cathepsin L-like protease | 0.0318 | 0.4176 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0318 | 0.4176 | 0.4176 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0318 | 0.4176 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0211 | 0.1126 | 0.1126 |
Onchocerca volvulus | 0.0318 | 0.4176 | 1 | |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0318 | 0.4176 | 0.4176 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0318 | 0.4176 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0318 | 0.4176 | 1 |
Plasmodium vivax | vivapain-2 | 0.0318 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0218 | 0.1329 | 0.3182 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0211 | 0.1126 | 0.2697 |
Onchocerca volvulus | 0.0318 | 0.4176 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0318 | 0.4176 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0318 | 0.4176 | 0.4176 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0318 | 0.4176 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0218 | 0.1329 | 0.1329 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0218 | 0.1329 | 0.3182 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0318 | 0.4176 | 0.3437 |
Loa Loa (eye worm) | hypothetical protein | 0.0318 | 0.4176 | 0.3437 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0318 | 0.4176 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0318 | 0.4176 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0318 | 0.4176 | 0.4176 |
Brugia malayi | Cathepsin L-like precursor | 0.0318 | 0.4176 | 0.4176 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0318 | 0.4176 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0218 | 0.1329 | 0.0228 |
Loa Loa (eye worm) | fibroinase | 0.0318 | 0.4176 | 0.3437 |
Leishmania major | cathepsin L-like protease | 0.0318 | 0.4176 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0318 | 0.4176 | 0.4176 |
Echinococcus granulosus | cathepsin b | 0.0524 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0318 | 0.4176 | 1 |
Leishmania major | cathepsin L-like protease | 0.0318 | 0.4176 | 1 |
Loa Loa (eye worm) | ctsf protein | 0.0318 | 0.4176 | 0.3437 |
Giardia lamblia | Cathepsin B precursor | 0.0211 | 0.1126 | 0.5 |
Leishmania major | cathepsin L-like protease | 0.0318 | 0.4176 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0318 | 0.4176 | 0.4176 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0218 | 0.1329 | 0.1329 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0318 | 0.4176 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0318 | 0.4176 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0318 | 0.4176 | 0.4176 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0318 | 0.4176 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0318 | 0.4176 | 1 |
Onchocerca volvulus | 0.0318 | 0.4176 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0218 | 0.1329 | 0.0228 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0318 | 0.4176 | 1 |
Brugia malayi | cathepsin L-like precursor | 0.0218 | 0.1329 | 0.1329 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0318 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0218 | 0.1329 | 0.3182 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0318 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0318 | 0.4176 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0524 | 1 | 1 |
Echinococcus granulosus | cathepsin b | 0.0524 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0318 | 0.4176 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0318 | 0.4176 | 0.4176 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0318 | 0.4176 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.