Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | cathepsin F (C01 family) | 0.0523 | 0.4176 | 0.4176 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0523 | 0.4176 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0523 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0523 | 0.4176 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0523 | 0.4176 | 0.4176 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0523 | 0.4176 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0523 | 0.4176 | 0.4176 |
Echinococcus granulosus | cathepsin l1 | 0.0523 | 0.4176 | 0.4176 |
Brugia malayi | Cathepsin L-like precursor | 0.0523 | 0.4176 | 0.4176 |
Brugia malayi | Cathepsin L-like precursor | 0.0357 | 0.1329 | 0.1329 |
Leishmania major | cathepsin L-like protease | 0.0523 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0523 | 0.4176 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0523 | 0.4176 | 1 |
Leishmania major | cathepsin L-like protease | 0.0523 | 0.4176 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.086 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0523 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0523 | 0.4176 | 1 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0523 | 0.4176 | 0.3437 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0523 | 0.4176 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0523 | 0.4176 | 0.4176 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.086 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0357 | 0.1329 | 0.3182 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0523 | 0.4176 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.086 | 1 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0523 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0523 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0523 | 0.4176 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0523 | 0.4176 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0523 | 0.4176 | 0.3437 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0523 | 0.4176 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0523 | 0.4176 | 0.4176 |
Leishmania major | cathepsin L-like protease | 0.0523 | 0.4176 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0523 | 0.4176 | 0.4176 |
Echinococcus granulosus | cathepsin b | 0.086 | 1 | 1 |
Echinococcus multilocularis | cathepsin b | 0.086 | 1 | 1 |
Onchocerca volvulus | 0.0523 | 0.4176 | 1 | |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0523 | 0.4176 | 0.4176 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0357 | 0.1329 | 0.1329 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0523 | 0.4176 | 0.4176 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0523 | 0.4176 | 0.4176 |
Loa Loa (eye worm) | fibroinase | 0.0523 | 0.4176 | 0.3437 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0523 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0523 | 0.4176 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0523 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0346 | 0.1126 | 0.2697 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0523 | 0.4176 | 1 |
Onchocerca volvulus | 0.0523 | 0.4176 | 1 | |
Echinococcus granulosus | cathepsin l1 | 0.0357 | 0.1329 | 0.1329 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0523 | 0.4176 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0523 | 0.4176 | 0.4176 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0346 | 0.1126 | 0.1126 |
Giardia lamblia | Cathepsin B precursor | 0.0346 | 0.1126 | 0.5 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0523 | 0.4176 | 0.3437 |
Onchocerca volvulus | 0.0523 | 0.4176 | 1 | |
Leishmania major | cathepsin L-like protease | 0.0523 | 0.4176 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0523 | 0.4176 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0523 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0523 | 0.4176 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0523 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0523 | 0.4176 | 1 |
Onchocerca volvulus | 0.0523 | 0.4176 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0523 | 0.4176 | 1 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.086 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0523 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0523 | 0.4176 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0523 | 0.4176 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0357 | 0.1329 | 0.0228 |
Leishmania major | cathepsin L-like protease | 0.0523 | 0.4176 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0523 | 0.4176 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0523 | 0.4176 | 0.4176 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0357 | 0.1329 | 0.3182 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0523 | 0.4176 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0523 | 0.4176 | 0.4176 |
Brugia malayi | cathepsin L-like precursor | 0.0357 | 0.1329 | 0.1329 |
Echinococcus granulosus | cathepsin b | 0.086 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0523 | 0.4176 | 1 |
Echinococcus multilocularis | cathepsin b | 0.086 | 1 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0523 | 0.4176 | 0.4176 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.086 | 1 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0523 | 0.4176 | 0.4176 |
Plasmodium vivax | vivapain-2 | 0.0523 | 0.4176 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0357 | 0.1329 | 0.0228 |
Plasmodium vivax | vivapain-2 | 0.0523 | 0.4176 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0523 | 0.4176 | 0.4176 |
Onchocerca volvulus | 0.0523 | 0.4176 | 1 | |
Leishmania major | cathepsin L-like protease | 0.0523 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0523 | 0.4176 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0523 | 0.4176 | 0.4176 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0523 | 0.4176 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0523 | 0.4176 | 1 |
Onchocerca volvulus | Cathepsin F homolog | 0.0523 | 0.4176 | 1 |
Leishmania major | cathepsin L-like protease | 0.0523 | 0.4176 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0523 | 0.4176 | 0.4176 |
Toxoplasma gondii | cathepsin CPL | 0.0523 | 0.4176 | 1 |
Loa Loa (eye worm) | cysteine protease | 0.0523 | 0.4176 | 0.3437 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0523 | 0.4176 | 1 |
Loa Loa (eye worm) | ctsf protein | 0.0523 | 0.4176 | 0.3437 |
Onchocerca volvulus | 0.0523 | 0.4176 | 1 | |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0346 | 0.1126 | 0.2697 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.086 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0357 | 0.1329 | 0.1329 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0523 | 0.4176 | 1 |
Leishmania major | cathepsin L-like protease | 0.0523 | 0.4176 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0523 | 0.4176 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0523 | 0.4176 | 0.4176 |
Loa Loa (eye worm) | hypothetical protein | 0.0357 | 0.1329 | 0.0228 |
Onchocerca volvulus | Cathepsin L homolog | 0.0523 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0523 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0357 | 0.1329 | 0.3182 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0523 | 0.4176 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0346 | 0.1126 | 0.5 |
Leishmania major | cysteine peptidase A (CPA) | 0.0523 | 0.4176 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0523 | 0.4176 | 0.4176 |
Brugia malayi | Cathepsin L-like precursor | 0.0357 | 0.1329 | 0.1329 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0523 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0523 | 0.4176 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0523 | 0.4176 | 0.4176 |
Giardia lamblia | Cathepsin B precursor | 0.0346 | 0.1126 | 0.5 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0346 | 0.1126 | 0.1126 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0357 | 0.1329 | 0.1329 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0523 | 0.4176 | 1 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0523 | 0.4176 | 0.4176 |
Onchocerca volvulus | 0.0523 | 0.4176 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.