Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | PAB1-binding protein , putative | 0.0027 | 0.0866 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0068 | 0.4565 | 1 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0128 | 1 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0068 | 0.4565 | 0.405 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0027 | 0.0866 | 0.5 |
Loa Loa (eye worm) | TAR-binding protein | 0.0068 | 0.4565 | 0.405 |
Brugia malayi | RNA binding protein | 0.0068 | 0.4565 | 0.4565 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.1911 | 0.5 |
Brugia malayi | hypothetical protein | 0.0039 | 0.1911 | 0.1911 |
Leishmania major | hypothetical protein, conserved | 0.0027 | 0.0866 | 0.5 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0068 | 0.4565 | 0.405 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0068 | 0.4565 | 0.4565 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0027 | 0.0866 | 0.5 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0027 | 0.0866 | 0.5 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0128 | 1 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.0068 | 0.4565 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0068 | 0.4565 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0068 | 0.4565 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.1911 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0068 | 0.4565 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.1911 | 0.5 |
Echinococcus multilocularis | tar DNA binding protein | 0.0068 | 0.4565 | 1 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0027 | 0.0866 | 0.5 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0027 | 0.0866 | 0.5 |
Brugia malayi | hypothetical protein | 0.0027 | 0.0866 | 0.0866 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.1911 | 0.5 |
Brugia malayi | TAR-binding protein | 0.0068 | 0.4565 | 0.4565 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0027 | 0.0866 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0068 | 0.4565 | 1 |
Species name | Source | Reference | Is orphan |
---|---|---|---|
Homo sapiens | ChEMBL23 | 24826815 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.