Detailed information for compound 1913799

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 1703.55 | Formula: C77H96Cl2F3N11O25
  • H donors: 20 H acceptors: 19 LogP: -0.29 Rotable bonds: 23
    Rule of 5 violations (Lipinski): 4
  • SMILES: [O-]C(=O)C(F)(F)F.CCCC[N+](CCCNC(=O)[C@H]1NC(=O)[C@H]2NC(=O)[C@@H](c3cc(c4c1cc(O)cc4O)c(O)cc3)NC(=O)[C@@H]1NC(=O)[C@H](CC(=O)N)NC(=O)[C@H](NC(=O)[C@@H](CC(C)C)NC)[C@H](O)c3ccc(Oc4cc1cc(Oc1ccc([C@H]2O)cc1Cl)c4O[C@@H]1O[C@H](CO)[C@H]([C@@H]([C@H]1O[C@@H]1O[C@@H](C)[C@H]([C@@](C1)(C)N)O)O)O)c(Cl)c3)(C)C
  • InChi: 1S/C75H95Cl2N11O23.C2HF3O2/c1-9-10-19-88(7,8)20-11-18-81-69(101)57-40-27-38(90)28-46(92)54(40)39-22-34(12-15-45(39)91)55-70(102)87-59(73(105)85-57)61(95)36-14-17-48(42(77)24-36)108-50-26-37-25-49(64(50)111-74-65(63(97)62(96)51(31-89)109-74)110-53-30-75(5,79)66(98)33(4)106-53)107-47-16-13-35(23-41(47)76)60(94)58(86-67(99)43(80-6)21-32(2)3)72(104)82-44(29-52(78)93)68(100)83-56(37)71(103)84-55;3-2(4,5)1(6)7/h12-17,22-28,32-33,43-44,51,53,55-63,65-66,74,80,89,94-98H,9-11,18-21,29-31,79H2,1-8H3,(H11-,78,81,82,83,84,85,86,87,90,91,92,93,99,100,101,102,103,104,105);(H,6,7)/t33-,43+,44-,51+,53-,55+,56+,57-,58+,59-,60+,61+,62+,63-,65+,66+,74-,75-;/m0./s1
  • InChiKey: IEFWDNUMGJEWNS-OSORPHAPSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Entamoeba histolytica hypothetical protein 0.0036 0.1381 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0578 0.4297
Echinococcus multilocularis smad 0.0008 0.0103 0.0138
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.0008 0.0106 0.0142
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.1346 1
Schistosoma mansoni smad 0.0008 0.0103 0.0138
Loa Loa (eye worm) MH2 domain-containing protein 0.0008 0.0103 0.0162
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0578 0.4297
Loa Loa (eye worm) MH1 domain-containing protein 0.0008 0.0103 0.0162
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0045 0.1831 0.2452
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0045 0.1831 0.2884
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0016 0.0456 0.3385
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.001 0.0213 0.1582
Loa Loa (eye worm) hypothetical protein 0.0117 0.513 0.8082
Loa Loa (eye worm) hypothetical protein 0.0035 0.1346 0.2121
Leishmania major hypothetical protein, conserved 0.0035 0.1346 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.178 0.2385
Echinococcus multilocularis Smad4 0.0008 0.0103 0.0138
Brugia malayi beta-lactamase 0.0035 0.1346 0.2121
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0018 0.0578 0.4297
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.001 0.0182 0.0244
Brugia malayi latrophilin 2 splice variant baaae 0.0098 0.4257 0.6706
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0578 0.4297
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0578 0.4297
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.1346 0.2121
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0045 0.1831 0.2452
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0578 0.4297
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0018 0.0578 0.0775
Mycobacterium ulcerans hypothetical protein 0.0035 0.1346 0.5
Toxoplasma gondii FATC domain-containing protein 0.0025 0.0892 0.6623
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.001 0.0213 0.1543
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0578 0.4297
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.1346 1
Echinococcus granulosus geminin 0.0168 0.7466 1
Echinococcus granulosus mothers against decapentaplegic 5 0.0008 0.0103 0.0138
Echinococcus multilocularis mothers against decapentaplegic 5 0.0008 0.0103 0.0138
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0143 0.6348 1
Schistosoma mansoni hypothetical protein 0.0045 0.1831 0.2452
Mycobacterium ulcerans lipase LipD 0.0035 0.1346 0.5
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0025 0.0892 0.6623
Trichomonas vaginalis esterase, putative 0.0035 0.1346 1
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0016 0.0464 0.3449
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0045 0.1831 0.2452
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0008 0.0103 0.0138
Schistosoma mansoni DNA helicase recq5 0.001 0.0182 0.0244
Loa Loa (eye worm) hypothetical protein 0.0098 0.4257 0.6706
Echinococcus granulosus bloom syndrome protein 0.0023 0.0811 0.1086
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0018 0.0578 0.4297
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.1346 0.5
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0018 0.0578 0.0775
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.1381 0.1849
Echinococcus granulosus ATP dependent DNA helicase Q1 0.001 0.0182 0.0244
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0578 0.4297
Loa Loa (eye worm) hypothetical protein 0.001 0.0213 0.0336
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.1346 1
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0312 0.232
Echinococcus granulosus serine protein kinase ATM 0.0025 0.0892 0.1194
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0018 0.0578 0.4297
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0578 0.4297
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0578 0.4297
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0578 0.0911
Loa Loa (eye worm) hypothetical protein 0.0021 0.073 0.1151
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0008 0.0103 0.0138
Mycobacterium leprae Probable lipase LipE 0.0035 0.1346 0.5
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0011 0.0267 0.1984
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0578 0.4297
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.002 0.0681 1
Brugia malayi Smad1 0.0008 0.0103 0.0162
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.1346 1
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.001 0.0213 0.0285
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0011 0.0267 0.1984
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.1346 1
Giardia lamblia GTOR 0.0018 0.0578 1
Loa Loa (eye worm) beta-lactamase 0.0035 0.1346 0.2121
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0021 0.073 0.5425
Trichomonas vaginalis DNA helicase recq, putative 0.0023 0.0811 0.6025
Echinococcus granulosus TGF beta signal transducer SmadC 0.0008 0.0103 0.0138
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.178 0.2385
Schistosoma mansoni hypothetical protein 0.0036 0.1381 0.1849
Trypanosoma cruzi target of rapamycin kinase 3 0.0018 0.0578 0.4297
Toxoplasma gondii target of rapamycin (TOR), putative 0.0018 0.0578 0.4297
Toxoplasma gondii ABC1 family protein 0.0035 0.1346 1
Brugia malayi hypothetical protein 0.0036 0.1381 0.2175
Echinococcus multilocularis geminin 0.0168 0.7466 1
Schistosoma mansoni smad1 5 8 and 0.0008 0.0103 0.0138
Brugia malayi MH2 domain containing protein 0.0116 0.5065 0.798
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0892 0.6623
Trichomonas vaginalis PIKK family atypical protein kinase 0.0007 0.0052 0.0385
Echinococcus multilocularis bloom syndrome protein 0.0023 0.0811 0.1086
Plasmodium vivax hypothetical protein, conserved 0.0035 0.1346 1
Loa Loa (eye worm) Smad1 0.0008 0.0103 0.0162
Entamoeba histolytica hypothetical protein 0.0036 0.1381 1
Mycobacterium leprae conserved hypothetical protein 0.0035 0.1346 0.5
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.1346 1
Brugia malayi Bloom's syndrome protein homolog 0.0023 0.0811 0.1278
Brugia malayi MH1 domain containing protein 0.0008 0.0103 0.0162
Loa Loa (eye worm) hypothetical protein 0.0035 0.1346 0.2121
Entamoeba histolytica hypothetical protein 0.0036 0.1381 1
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.001 0.0182 0.0287
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0018 0.0578 0.0775
Echinococcus granulosus serine:threonine protein kinase SMG1 0.001 0.0213 0.0285
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.001 0.0182 0.1354
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.1346 0.1803
Loa Loa (eye worm) hypothetical protein 0.0143 0.6348 1
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0025 0.0892 0.1405
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0044 0.178 0.2805
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0018 0.0578 0.4297
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0018 0.0578 0.0775
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0578 0.4297
Loa Loa (eye worm) hypothetical protein 0.0045 0.1831 0.2884
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0018 0.0578 0.0775
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0018 0.0578 0.4297
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0018 0.0578 0.4297
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0578 0.4297
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.1346 0.1803
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0018 0.058 0.4309
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.1346 0.1803
Onchocerca volvulus 0.0035 0.1346 1
Mycobacterium ulcerans beta-lactamase 0.0035 0.1346 0.5
Onchocerca volvulus 0.0035 0.1346 1
Schistosoma mansoni smad1 5 8 and 0.0008 0.0103 0.0138
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.178 0.2385
Loa Loa (eye worm) MH2 domain-containing protein 0.0116 0.5065 0.798
Entamoeba histolytica hypothetical protein 0.0036 0.1381 1
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0018 0.0578 0.4297
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0578 0.4297
Schistosoma mansoni fkbp-rapamycin associated protein 0.001 0.0213 0.0285
Brugia malayi Calcitonin receptor-like protein seb-1 0.0143 0.6348 1
Schistosoma mansoni hypothetical protein 0.0045 0.1831 0.2452
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0044 0.178 0.2805
Entamoeba histolytica protein kinase rad3, putative 0.001 0.0213 0.1543
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0578 0.4297
Echinococcus granulosus smad 0.0008 0.0103 0.0138
Entamoeba histolytica recQ family helicase, putative 0.0012 0.0312 0.2262
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.1346 0.2121
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0018 0.0578 0.4297
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0267 0.1984
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0018 0.0578 0.4297
Schistosoma mansoni hypothetical protein 0.0168 0.7466 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0267 0.1984
Loa Loa (eye worm) hypothetical protein 0.0035 0.1346 0.2121
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.1346 1
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0018 0.0578 0.4297
Entamoeba histolytica hypothetical protein 0.0025 0.0892 0.6458
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.001 0.0182 0.0244
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0578 0.4297
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0312 0.232
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.001 0.0213 0.0336
Echinococcus granulosus GPCR family 2 0.0045 0.1831 0.2452
Loa Loa (eye worm) hypothetical protein 0.001 0.0182 0.0287
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.1381 0.1849
Trichomonas vaginalis PIKK family atypical protein kinase 0.001 0.0213 0.1582
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0018 0.0578 0.0775
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0143 0.6348 1
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0025 0.0892 0.1194
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.0008 0.0106 0.0142
Loa Loa (eye worm) hypothetical protein 0.0035 0.1346 0.2121
Trichomonas vaginalis PIKK family atypical protein kinase 0.001 0.0213 0.1582
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.1346 0.5
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.1346 1
Echinococcus granulosus Smad4 0.0008 0.0103 0.0138
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0018 0.0578 0.419
Schistosoma mansoni hypothetical protein 0.0098 0.4257 0.5702
Schistosoma mansoni DNA helicase recq1 0.001 0.0182 0.0244
Brugia malayi beta-lactamase family protein 0.0035 0.1346 0.2121
Trichomonas vaginalis PIKK family atypical protein kinase 0.001 0.0213 0.1582
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0578 0.4297
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0578 0.4297
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0052 0.0385
Loa Loa (eye worm) transcription factor SMAD2 0.0116 0.5065 0.798
Schistosoma mansoni hypothetical protein 0.0045 0.1831 0.2452
Echinococcus multilocularis GPCR, family 2 0.0045 0.1831 0.2452
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0018 0.0578 0.419
Brugia malayi MH2 domain containing protein 0.0008 0.0103 0.0162
Brugia malayi Latrophilin receptor protein 2 0.0045 0.1831 0.2884
Trichomonas vaginalis PIKK family atypical protein kinase 0.001 0.0213 0.1582
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.178 0.2385
Trichomonas vaginalis PIKK family atypical protein kinase 0.001 0.0213 0.1582
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0578 0.4297
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0578 0.4297
Giardia lamblia Sgs1 DNA helicase, putative 0.001 0.0182 0.3151
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0312 0.232
Schistosoma mansoni blooms syndrome DNA helicase 0.0018 0.0586 0.0785
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0025 0.0892 0.6623
Loa Loa (eye worm) RecQ helicase 0.0023 0.0811 0.1278
Schistosoma mansoni smad1 5 8 and 0.0008 0.0103 0.0138
Loa Loa (eye worm) latrophilin receptor protein 2 0.0045 0.1831 0.2884
Trichomonas vaginalis PIKK family atypical protein kinase 0.001 0.0213 0.1582
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0578 0.4297
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0578 0.4297
Brugia malayi MH1 domain containing protein 0.0008 0.0103 0.0162
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.001 0.0182 0.2677
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.1381 0.1849
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0018 0.0578 0.4297
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.178 0.2385
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0018 0.0578 0.4297
Schistosoma mansoni hypothetical protein 0.0045 0.1831 0.2452
Brugia malayi FAT domain containing protein 0.0008 0.0106 0.0167
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.178 0.2385
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0578 0.4297
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.001 0.0182 0.1354
Schistosoma mansoni hypothetical protein 0.0168 0.7466 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0578 0.4297
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0578 0.0911
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0578 0.4297
Brugia malayi MH2 domain containing protein 0.0008 0.0103 0.0162
Echinococcus granulosus ATP dependent DNA helicase Q5 0.001 0.0182 0.0244
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0578 0.4297
Loa Loa (eye worm) hypothetical protein 0.0035 0.1346 0.2121
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0018 0.0578 0.4297
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0578 0.0911
Loa Loa (eye worm) hypothetical protein 0.0011 0.0267 0.0421
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.178 0.2385
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0578 0.4297
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0106 0.0786
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.001 0.0182 0.0287
Trichomonas vaginalis DNA helicase recq1, putative 0.0023 0.0811 0.6025
Loa Loa (eye worm) ATP-dependent DNA helicase 0.001 0.0182 0.0287
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0045 0.1831 0.2452
Echinococcus multilocularis serine protein kinase ATM 0.0025 0.0892 0.1194
Loa Loa (eye worm) hypothetical protein 0.0035 0.1346 0.2121
Schistosoma mansoni Smad4 0.0008 0.0103 0.0138
Onchocerca volvulus 0.0035 0.1346 1
Schistosoma mansoni hypothetical protein 0.0008 0.0106 0.0142
Brugia malayi beta-lactamase family protein 0.0035 0.1346 0.2121
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.1346 0.1803
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0578 0.0911
Leishmania major phosphatidylinositol 3-kinase, putative 0.0018 0.0578 0.4297
Leishmania major phosphatidylinositol kinase related protein, putative 0.0018 0.058 0.4309
Trichomonas vaginalis PIKK family atypical protein kinase 0.001 0.0213 0.1582
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0578 0.4297
Trichomonas vaginalis DNA helicase recq, putative 0.0012 0.0312 0.232
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0578 0.4297
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0578 0.4297
Loa Loa (eye worm) hypothetical protein 0.0008 0.0106 0.0167

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.