Detailed information for compound 1913907

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 183.236 | Formula: C9H16N2O2
  • H donors: 2 H acceptors: 2 LogP: 1.31 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCC1(CCC)NC(=O)N[11C]1=O
  • InChi: 1S/C9H16N2O2/c1-3-5-9(6-4-2)7(12)10-8(13)11-9/h3-6H2,1-2H3,(H2,10,11,12,13)/i7-1
  • InChiKey: TVKULRRHIFBSPZ-JZRMKITLSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Pao retrotransposon peptidase family protein 0.0024 0.0013 0.0042
Loa Loa (eye worm) thymidylate kinase 0.0087 0.0631 0.1998
Loa Loa (eye worm) DNA polymerase epsilon catalytic subunit 0.0079 0.0551 0.1744
Trypanosoma cruzi DNA polymerase delta catalytic subunit, putative 0.0257 0.2286 0.3533
Loa Loa (eye worm) hypothetical protein 0.0115 0.0899 0.2847
Treponema pallidum ribonuclease H (rnhA) 0.0101 0.0761 1
Trypanosoma brucei Endonuclease-reverse transcriptase/Reverse transcriptase (RNA-dependent DNA polymerase), putative 0.0024 0.0013 0.0013
Trichomonas vaginalis thymidine kinase, putative 0.0282 0.253 0.828
Leishmania major cathepsin L-like protease 0.0074 0.05 0.0774
Schistosoma mansoni phosphoglucomutase 0.0101 0.0761 0.0761
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0097 0.0722 0.1116
Schistosoma mansoni DNA polymerase zeta catalytic subunit 0.0142 0.1167 0.1167
Echinococcus multilocularis RNA directed DNA polymerase 0.0024 0.0013 0.0042
Loa Loa (eye worm) hypothetical protein 0.0063 0.0398 0.126
Onchocerca volvulus DNA polymerase homolog 0.0142 0.1167 0.367
Schistosoma mansoni hypothetical protein 0.0087 0.0631 0.0631
Trypanosoma cruzi major cysteine proteinase, putative 0.0058 0.0347 0.0536
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0097 0.0722 0.0722
Brugia malayi Pao retrotransposon peptidase family protein 0.0024 0.0013 0.0042
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0084 0.0595 0.1802
Loa Loa (eye worm) hypothetical protein 0.0079 0.0551 0.1744
Echinococcus granulosus RNA directed DNA polymerase reverse transcriptase 0.0024 0.0013 0.0042
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0097 0.0722 0.1116
Echinococcus granulosus DNA polymerase subunit gamma 0.0115 0.0899 0.2943
Trichomonas vaginalis thymidylate kinase, putative 0.0087 0.0631 0.2065
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.05 0.05
Trypanosoma cruzi hypothetical protein, conserved 0.0024 0.0013 0.002
Echinococcus multilocularis DNA polymerase zeta catalytic subunit 0.0142 0.1167 0.382
Entamoeba histolytica DNA polymerase zeta catalytic subunit, putative 0.0063 0.0398 0.1302
Schistosoma mansoni phosphoglucomutase 0.0101 0.0761 0.0761
Onchocerca volvulus DNA polymerase alpha catalytic subunit homolog 0.0347 0.3158 1
Leishmania major ribonuclease H1, putative 0.0101 0.0761 0.1176
Trypanosoma cruzi thymidine kinase, putative 0.0282 0.253 0.391
Trypanosoma cruzi cysteine peptidase, putative 0.0074 0.05 0.0774
Leishmania major thymidylate kinase-like protein 0.0087 0.0631 0.0975
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.05 0.05
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0024 0.0013 0.0042
Plasmodium vivax DNA polymerase epsilon, catalytic subunit a, putative 0.0142 0.1167 0.3528
Brugia malayi Thioredoxin reductase 0.0037 0.0138 0.0452
Loa Loa (eye worm) cytochrome P450 family protein 0.003 0.0076 0.0241
Trichomonas vaginalis DNA polymerase alpha catalytic subunit, putative 0.0079 0.0551 0.1802
Brugia malayi RNase H family protein 0.0101 0.0761 0.2491
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0118 0.0927 0.1434
Brugia malayi RNase H family protein 0.0101 0.0761 0.2491
Brugia malayi Pao retrotransposon peptidase family protein 0.0024 0.0013 0.0042
Trichomonas vaginalis DNA polymerase delta catalytic subunit, putative 0.0142 0.1167 0.382
Giardia lamblia DNA polymerase alpha subunit A 0.0198 0.171 0.5596
Giardia lamblia Reverse transcriptase/endonuclease 0.0024 0.0013 0.0042
Onchocerca volvulus Ribonuclease H1 homolog 0.0101 0.0761 0.2379
Trypanosoma brucei DNA polymerase zeta catalytic subunit, putative 0.0142 0.1167 0.1167
Plasmodium vivax DNA polymerase alpha, putative 0.0242 0.2137 0.6851
Brugia malayi reverse transcriptase 0.0024 0.0013 0.0042
Trypanosoma cruzi DNA polymerase I alpha catalytic subunit, putative 0.0172 0.1458 0.2253
Leishmania major mitochondrial DNA polymerase beta 0.0686 0.647 1
Onchocerca volvulus DNA polymerase delta catalytic subunit homolog 0.0336 0.3055 0.9673
Giardia lamblia Reverse transcriptase/endonuclease, putative 0.0024 0.0013 0.0042
Echinococcus granulosus ribonuclease H1 0.0101 0.0761 0.2491
Brugia malayi reverse transcriptase 0.0024 0.0013 0.0042
Schistosoma mansoni phosphoglucomutase 0.0101 0.0761 0.0761
Trichomonas vaginalis thymidylate kinase, putative 0.0087 0.0631 0.2065
Entamoeba histolytica DNA polymerase delta catalytic subunit, putative 0.0336 0.3055 1
Plasmodium falciparum DNA polymerase alpha catalytic subunit A 0.0093 0.0688 0.1886
Trichomonas vaginalis reverse transcriptase [C. elegans], putative 0.0024 0.0013 0.0042
Mycobacterium tuberculosis Probable dehydrogenase 0.0084 0.0595 0.1802
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0024 0.0013 0.0042
Loa Loa (eye worm) DNA-directed DNA polymerase III 0.0336 0.3055 0.9675
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.05 0.05
Echinococcus multilocularis dna polymerase epsilon catalytic subunit a 0.0142 0.1167 0.382
Echinococcus multilocularis DNA polymerase alpha catalytic subunit 0.0277 0.2479 0.8114
Brugia malayi Pao retrotransposon peptidase family protein 0.0024 0.0013 0.0042
Trypanosoma cruzi DNA polymerase epsilon catalytic subunit, putative 0.0142 0.1167 0.1804
Leishmania major trypanothione reductase 0.0037 0.0138 0.0214
Loa Loa (eye worm) hypothetical protein 0.0347 0.3158 1
Trypanosoma brucei ingi protein (ORF1) 0.0124 0.0992 0.0992
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0067 0.0438 0.0677
Trichomonas vaginalis reverse transcriptases, putative 0.0024 0.0013 0.0042
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0325 0.2947 0.4555
Trichomonas vaginalis DNA polymerase zeta catalytic subunit, putative 0.0336 0.3055 1
Trypanosoma cruzi DNA polymerase epsilon catalytic subunit, putative 0.0142 0.1167 0.1804
Echinococcus granulosus RNA directed DNA polymerase reverse transcriptase 0.0024 0.0013 0.0042
Brugia malayi hypothetical protein 0.0024 0.0013 0.0042
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.05 0.05
Trichomonas vaginalis DNA polymerase alpha catalytic subunit, putative 0.0172 0.1458 0.4771
Mycobacterium tuberculosis Thymidylate kinase Tmk (dTMP kinase) (thymidylic acid kinase) (TMPK) 0.0087 0.0631 0.1909
Brugia malayi Pao retrotransposon peptidase family protein 0.0024 0.0013 0.0042
Schistosoma mansoni protein kinase 0.0024 0.0013 0.0013
Trypanosoma cruzi cysteine peptidase, putative 0.0074 0.05 0.0774
Trypanosoma brucei DNA polymerase epsilon catalytic subunit, putative 0.0142 0.1167 0.1167
Leishmania major DNA polymerase I alpha catalytic subunit, putative 0.0172 0.1458 0.2253
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0024 0.0013 0.0042
Plasmodium falciparum DNA polymerase epsilon catalytic subunit A, putative 0.0079 0.0551 0.1414
Brugia malayi Pao retrotransposon peptidase family protein 0.0024 0.0013 0.0042
Trypanosoma cruzi UMP-CMP kinase, mitochondrial, putative 0.0034 0.0115 0.0177
Echinococcus granulosus thioredoxin glutathione reductase 0.0037 0.0143 0.0468
Trypanosoma brucei DNA polymerase delta catalytic subunit, putative 0.0336 0.3055 0.3055
Trypanosoma cruzi ribonuclease H1, putative 0.0101 0.0761 0.1176
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0084 0.0595 0.1802
Trypanosoma brucei SLACS retrotransposable element (part), putative 0.0024 0.0013 0.0013
Echinococcus granulosus RNA directed DNA polymerase 0.0024 0.0013 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0063 0.0398 0.1302
Plasmodium vivax DNA polymerase delta catalytic subunit, putative 0.0336 0.3055 1
Trichomonas vaginalis ribonuclease H1, putative 0.0101 0.0761 0.2491
Schistosoma mansoni DNA polymerase gamma 0.0115 0.0899 0.0899
Onchocerca volvulus DNA polymerase epsilon catalytic subunit A homolog 0.0142 0.1167 0.367
Mycobacterium ulcerans hypothetical protein 0.0362 0.3304 1
Echinococcus granulosus DNA polymerase delta catalytic subunit 0.0336 0.3055 1
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0686 0.647 1
Schistosoma mansoni DNA polymerase epsilon catalytic subunit 0.0142 0.1167 0.1167
Schistosoma mansoni serine/threonine protein kinase 0.0024 0.0013 0.0013
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0024 0.0013 0.0042
Trypanosoma cruzi cysteine peptidase, putative 0.0074 0.05 0.0774
Trichomonas vaginalis DNA polymerase II, putative 0.0172 0.1458 0.4771
Brugia malayi RNase H family protein 0.0101 0.0761 0.2491
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0024 0.0013 0.0042
Leishmania major cathepsin L-like protease 0.0074 0.05 0.0774
Mycobacterium tuberculosis Possible maturase 0.0024 0.0013 0.0039
Echinococcus multilocularis thioredoxin glutathione reductase 0.0037 0.0143 0.0468
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0093 0.0686 0.2077
Trypanosoma brucei DNA polymerase alpha catalytic subunit 0.0172 0.1458 0.1458
Mycobacterium ulcerans thymidylate kinase 0.0087 0.0631 0.1909
Toxoplasma gondii thymidylate kinase 0.0087 0.0631 0.1689
Mycobacterium tuberculosis Probable reductase 0.0084 0.0595 0.1802
Brugia malayi Pao retrotransposon peptidase family protein 0.0024 0.0013 0.0042
Trypanosoma brucei thymidylate kinase, putative 0.0087 0.0631 0.0631
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0024 0.0013 0.0042
Mycobacterium leprae probable thymidylate kinase Tmk (dTMP KINASE) (THYMIDYLIC ACID KINASE) (TMPK) 0.0087 0.0631 0.3897
Trypanosoma brucei RNA helicase, putative 0.1049 1 1
Trypanosoma brucei thymidylate kinase, putative 0.0087 0.0631 0.0631
Trichomonas vaginalis reverse transcriptases, putative 0.0024 0.0013 0.0042
Plasmodium falciparum DNA polymerase delta catalytic subunit 0.0336 0.3055 1
Brugia malayi Pao retrotransposon peptidase family protein 0.0024 0.0013 0.0042
Giardia lamblia Reverse transcriptase/endonuclease, putative 0.0024 0.0013 0.0042
Schistosoma mansoni DNA polymerase alpha catalytic subunit 0.0277 0.2479 0.2479
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0093 0.0686 0.2077
Onchocerca volvulus Putative thymidylate kinase 0.0087 0.0631 0.1965
Echinococcus granulosus RNA directed DNA polymerase reverse transcriptase 0.0024 0.0013 0.0042
Brugia malayi glutathione reductase 0.0037 0.0138 0.0452
Echinococcus granulosus DNA polymerase alpha catalytic subunit 0.0277 0.2479 0.8114
Brugia malayi thymidylate kinase 0.0087 0.0631 0.2065
Entamoeba histolytica thymidine kinase, putative 0.0282 0.253 0.828
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.05 0.05
Schistosoma mansoni DNA polymerase delta catalytic subunit 0.0336 0.3055 0.3055
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0024 0.0013 0.0042
Brugia malayi hypothetical protein 0.0024 0.0013 0.0042
Brugia malayi reverse transcriptase 0.0024 0.0013 0.0042
Entamoeba histolytica DNA polymerase alpha catalytic subunit, putative 0.0093 0.0688 0.2253
Brugia malayi Zinc knuckle family protein 0.0024 0.0013 0.0042
Brugia malayi Pao retrotransposon peptidase family protein 0.0024 0.0013 0.0042
Trypanosoma cruzi cruzipain precursor, putative 0.0074 0.05 0.0774
Loa Loa (eye worm) DNA polymerase epsilon catalytic subunit 0.0063 0.0398 0.126
Schistosoma mansoni thymidylate kinase 0.0087 0.0631 0.0631
Echinococcus granulosus thymidylate kinase 0.0087 0.0631 0.2065
Brugia malayi Pao retrotransposon peptidase family protein 0.0024 0.0013 0.0042
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0084 0.0595 0.1802
Giardia lamblia CDC8 0.0087 0.0631 0.2065
Plasmodium vivax DNA polymerase zeta catalytic subunit, putative 0.0142 0.1167 0.3528
Brugia malayi Pao retrotransposon peptidase family protein 0.0024 0.0013 0.0042
Trypanosoma brucei hypothetical protein, conserved 0.0124 0.0992 0.0992
Echinococcus granulosus dna polymerase epsilon catalytic subunit a 0.0142 0.1167 0.382
Toxoplasma gondii ribonuclease HI protein 0.0101 0.0761 0.2135
Trypanosoma brucei unspecified product 0.0124 0.0992 0.0992
Schistosoma mansoni scy1(yeast) protein kinase-like 0.0024 0.0013 0.0013
Brugia malayi hypothetical protein 0.0024 0.0013 0.0042
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0037 0.0138 0.0418
Echinococcus multilocularis ribonuclease H1 0.0101 0.0761 0.2491
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0325 0.2947 0.4555
Trypanosoma cruzi trypanothione reductase, putative 0.0037 0.0138 0.0214
Plasmodium vivax thymidylate kinase, putative 0.0087 0.0631 0.1689
Plasmodium falciparum DNA polymerase zeta catalytic subunit, putative 0.0063 0.0398 0.089
Trichomonas vaginalis thymidine kinase, putative 0.0282 0.253 0.828
Leishmania major hypothetical protein, conserved 0.0034 0.0115 0.0177
Brugia malayi DNA polymerase alpha catalytic subunit 0.0242 0.2137 0.6993
Trypanosoma brucei trypanothione reductase 0.0037 0.0138 0.0138
Schistosoma mansoni DNA polymerase alpha catalytic subunit 0.007 0.046 0.046
Loa Loa (eye worm) thioredoxin reductase 0.0037 0.0138 0.0438
Trypanosoma cruzi DNA polymerase zeta catalytic subunit, putative 0.0063 0.0398 0.0615
Brugia malayi DNA polymerase delta catalytic subunit 0.0336 0.3055 1
Trichomonas vaginalis DNA polymerase alpha catalytic subunit, putative 0.0142 0.1167 0.382
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0097 0.0722 0.1116
Wolbachia endosymbiont of Brugia malayi ribonuclease HI 0.0101 0.0761 1
Leishmania major DNA polymerase zeta catalytic subunit, putative 0.0063 0.0398 0.0615
Giardia lamblia Reverse transcriptase/endonuclease, putative 0.0024 0.0013 0.0042
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.05 0.05
Leishmania major DNA polymerase epsilon catalytic subunit, putative 0.0142 0.1167 0.1804
Loa Loa (eye worm) glutathione reductase 0.0037 0.0138 0.0438
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0686 0.647 0.647
Toxoplasma gondii DNA polymerase family B protein 0.0063 0.0398 0.089
Chlamydia trachomatis thymidylate kinase 0.0087 0.0631 0.5
Echinococcus granulosus DNA polymerase zeta catalytic subunit 0.0142 0.1167 0.382
Leishmania major DNA polymerase delta catalytic subunit, putative 0.0336 0.3055 0.4722
Giardia lamblia Thymidine kinase 0.0282 0.253 0.828
Toxoplasma gondii DNA polymerase (pol2) superfamily protein 0.0242 0.2137 0.6851
Trypanosoma cruzi thymidylate kinase, putative 0.0087 0.0631 0.0975
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0024 0.0013 0.0042
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.05 0.05
Trypanosoma brucei thymidine kinase 0.0282 0.253 0.253
Toxoplasma gondii DNA polymerase 0.0336 0.3055 1
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0686 0.647 1
Trichomonas vaginalis NeSL-1_NeSL reverse transcriptases, putative 0.0024 0.0013 0.0042
Trypanosoma brucei SLACS reverse transcriptase, putative 0.0024 0.0013 0.0013
Schistosoma mansoni hypothetical protein 0.0024 0.0013 0.0013
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0093 0.0686 1
Brugia malayi DNA polymerase I family protein 0.0115 0.0899 0.2943
Brugia malayi Pao retrotransposon peptidase family protein 0.0024 0.0013 0.0042
Entamoeba histolytica Thymidylate kinase, putative 0.0087 0.0631 0.2065
Giardia lamblia DNA polymerase epsilon, catalytic subunit 0.0142 0.1167 0.382
Toxoplasma gondii hypothetical protein 0.0111 0.086 0.2475
Echinococcus multilocularis hypothetical protein 0.0115 0.0899 0.2943
Toxoplasma gondii DNA polymerase family B protein 0.0142 0.1167 0.3528
Trypanosoma cruzi thymidine kinase, putative 0.0282 0.253 0.391
Trypanosoma cruzi thymidylate kinase, putative 0.0087 0.0631 0.0975
Loa Loa (eye worm) hypothetical protein 0.0079 0.0551 0.1744
Schistosoma mansoni thymidylate kinase 0.0087 0.0631 0.0631
Echinococcus multilocularis thymidylate kinase 0.0087 0.0631 0.2065
Trypanosoma cruzi ribonuclease H1, putative 0.0101 0.0761 0.1176
Plasmodium falciparum thymidylate kinase 0.0087 0.0631 0.1689
Trypanosoma brucei ribonuclease H1 0.0101 0.0761 0.0761
Loa Loa (eye worm) hypothetical protein 0.0063 0.0398 0.126
Schistosoma mansoni hypothetical protein 0.0024 0.0013 0.0013
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.05 0.05
Leishmania major cathepsin L-like protease 0.0074 0.05 0.0774
Brugia malayi Cytochrome P450 family protein 0.003 0.0076 0.0249
Trichomonas vaginalis thymidine kinase, putative 0.0282 0.253 0.828
Giardia lamblia DNA polymerase delta, catalytic subunit 0.0336 0.3055 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.05 0.05
Echinococcus granulosus KRAB A domain containing protein 0.0024 0.0013 0.0042
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0024 0.0013 0.0042
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0325 0.2947 0.2947
Brugia malayi Pao retrotransposon peptidase family protein 0.0024 0.0013 0.0042
Trypanosoma brucei retrotransposon hot spot protein 4 (RHS4), interrupted 0.0124 0.0992 0.0992
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.05 0.05
Mycobacterium tuberculosis Probable oxidoreductase 0.0093 0.0686 0.2077
Brugia malayi Pao retrotransposon peptidase family protein 0.0024 0.0013 0.0042
Echinococcus multilocularis DNA polymerase delta catalytic subunit 0.0336 0.3055 1
Leishmania major thymidine kinase, putative 0.0282 0.253 0.391
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.05 0.05
Trypanosoma cruzi DNA polymerase delta catalytic subunit, putative 0.0336 0.3055 0.4722
Trypanosoma cruzi UMP-CMP kinase, mitochondrial, putative 0.0034 0.0115 0.0177
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0024 0.0013 0.0042
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0084 0.0595 0.1802
Brugia malayi hypothetical protein 0.0024 0.0013 0.0042
Trypanosoma brucei ingi protein (ORF1) 0.0124 0.0992 0.0992
Mycobacterium tuberculosis Conserved hypothetical protein 0.0362 0.3304 1
Giardia lamblia Ribonuclease H 0.0101 0.0761 0.2491
Echinococcus granulosus RNA directed DNA polymerase reverse transcriptase 0.0024 0.0013 0.0042
Brugia malayi Zinc knuckle family protein 0.0024 0.0013 0.0042
Brugia malayi DNA polymerase family B, exonuclease domain containing protein 0.0142 0.1167 0.382
Giardia lamblia Reverse transcriptase/endonuclease, putative 0.0024 0.0013 0.0042
Brugia malayi DNA polymerase family B containing protein 0.0142 0.1167 0.382

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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