Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | hypothetical protein | 0.0034 | 1 | 1 |
Trichomonas vaginalis | chaperonin, putative | 0.0024 | 0 | 0.5 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0034 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0034 | 1 | 1 |
Leishmania major | T-complex protein 1, beta subunit, putative | 0.0024 | 0 | 0.5 |
Trichomonas vaginalis | chaperonin-60kD, ch60, putative | 0.0024 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 1 | 1 |
Giardia lamblia | TCP-1 chaperonin subunit beta | 0.0024 | 0 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0034 | 1 | 1 |
Plasmodium falciparum | T-complex protein 1 subunit beta | 0.0024 | 0 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0034 | 1 | 1 |
Loa Loa (eye worm) | T-complex protein 1 | 0.0024 | 0 | 0.5 |
Plasmodium vivax | T-complex protein 1 subunit beta, putative | 0.0024 | 0 | 0.5 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0034 | 1 | 1 |
Toxoplasma gondii | t-complex protein beta subunit | 0.0024 | 0 | 0.5 |
Trypanosoma brucei | T-complex protein 1, beta subunit, putative | 0.0024 | 0 | 0.5 |
Trypanosoma cruzi | T-complex protein 1, beta subunit, putative | 0.0024 | 0 | 0.5 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0034 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.