Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | hypothetical protein | 0.0041 | 0.19 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0142 | 0.9182 | 0.9073 |
Echinococcus multilocularis | musashi | 0.003 | 0.117 | 0.1135 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0142 | 0.9182 | 0.9178 |
Echinococcus granulosus | lamin dm0 | 0.003 | 0.117 | 0.1236 |
Schistosoma mansoni | thyroid hormone receptor | 0.0154 | 1 | 1 |
Onchocerca volvulus | 0.003 | 0.117 | 0.5 | |
Entamoeba histolytica | hypothetical protein | 0.0041 | 0.19 | 0.5 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0041 | 0.19 | 0.2034 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.003 | 0.117 | 1 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0041 | 0.19 | 0.0826 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0016 | 0.0156 | 0.1333 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.113 | 0.9658 |
Loa Loa (eye worm) | intermediate filament protein | 0.003 | 0.117 | 1 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0142 | 0.9182 | 1 |
Echinococcus multilocularis | lamin dm0 | 0.003 | 0.117 | 0.1135 |
Echinococcus granulosus | intermediate filament protein | 0.003 | 0.117 | 0.1236 |
Brugia malayi | hypothetical protein | 0.0041 | 0.19 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0154 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.004 | 0.0342 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.003 | 0.117 | 0.5815 |
Entamoeba histolytica | hypothetical protein | 0.0041 | 0.19 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0041 | 0.19 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.117 | 1 |
Onchocerca volvulus | 0.003 | 0.117 | 0.5 | |
Echinococcus granulosus | lamin | 0.003 | 0.117 | 0.1236 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.19 | 0.0826 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0041 | 0.19 | 0.1867 |
Echinococcus multilocularis | lamin | 0.003 | 0.117 | 0.1135 |
Brugia malayi | intermediate filament protein | 0.003 | 0.117 | 0.5815 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.