Detailed information for compound 1936074

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 255.309 | Formula: C9H19O6S+
  • H donors: 6 H acceptors: 6 LogP: -2.56 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 2
  • SMILES: OC[C@@H]([C@@H](C[S@+]1C[C@@H]([C@H]([C@@H]1CO)O)O)O)O
  • InChi: 1S/C9H19O6S/c10-1-5(12)6(13)3-16-4-7(14)9(15)8(16)2-11/h5-15H,1-4H2/q+1/t5-,6+,7-,8-,9+,16-/m0/s1
  • InChiKey: UOUAEIUEKYLOBU-GEOVGMEOSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi MH2 domain containing protein 0.0098 0.0941 0.0969
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0082 0.0755 0.1391
Loa Loa (eye worm) hypothetical protein 0.0025 0.0103 0.0106
Mycobacterium leprae Probable lipase LipE 0.0073 0.0653 0.3583
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0039 0.0262 0.033
Entamoeba histolytica hypothetical protein 0.0025 0.0103 0.0189
Trichomonas vaginalis hypothetical protein 0.0025 0.0103 0.0121
Plasmodium falciparum glutathione reductase 0.0038 0.0251 0.0462
Echinococcus granulosus histone lysine methyltransferase setb 0.0095 0.0908 0.1673
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0026 0.011 0.0203
Trypanosoma brucei hypothetical protein, conserved 0.0704 0.7935 1
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0027 0.0126 0.0126
Onchocerca volvulus 0.0047 0.0355 0.0281
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0053 0.0428 0.0428
Schistosoma mansoni hypothetical protein 0.0061 0.0521 0.0521
Echinococcus multilocularis tumor protein p63 0.0241 0.2594 0.478
Echinococcus granulosus neurogenic locus notch protein 0.0027 0.0126 0.0232
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0101 0.0973 0.0973
Treponema pallidum fructose-bisphosphate aldolase 0.0322 0.3524 1
Loa Loa (eye worm) hypothetical protein 0.0026 0.0107 0.011
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0261 0.0309
Brugia malayi Calcitonin receptor-like protein seb-1 0.0194 0.2051 0.2113
Onchocerca volvulus 0.0073 0.0653 0.0592
Schistosoma mansoni phd/f-box containing protein 0.003 0.0158 0.0158
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0126 0.1268 0.2282
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.003 0.0162 0.0299
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0019 0.0027 0.0049
Echinococcus multilocularis tissue type plasminogen activator 0.0191 0.2014 0.3712
Trypanosoma brucei glucosidase, putative 0.0082 0.0755 0.0951
Brugia malayi hypothetical protein 0.0025 0.0103 0.0106
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0294 0.0348
Echinococcus multilocularis chromobox protein 1 0.0154 0.1584 0.2919
Echinococcus multilocularis Chromobox protein 3 0.0025 0.0103 0.0189
Plasmodium vivax hypothetical protein, conserved 0.0093 0.0882 0.1463
Schistosoma mansoni hypothetical protein 0.0027 0.0126 0.0126
Schistosoma mansoni slit 0.0027 0.0126 0.0126
Toxoplasma gondii Amylo-alpha-1,6-glucosidase 0.0157 0.1618 0.2982
Echinococcus multilocularis peregrin 0.0094 0.0898 0.1656
Brugia malayi GCC2 and GCC3 family protein 0.0027 0.0126 0.013
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0126 0.1268 0.2337
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0191 0.2014 0.3591
Brugia malayi SEA domain containing protein 0.0069 0.0611 0.063
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0117 0.0138
Echinococcus multilocularis GPCR, family 2 0.0061 0.0521 0.096
Brugia malayi Pre-SET motif family protein 0.0659 0.7413 0.7638
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0026 0.011 0.5
Echinococcus granulosus slit 2 protein 0.0027 0.0126 0.0232
Schistosoma mansoni hypothetical protein 0.0061 0.0521 0.0521
Brugia malayi jmjC domain containing protein 0.0303 0.3314 0.3414
Schistosoma mansoni hypothetical protein 0.0335 0.3678 0.3678
Brugia malayi hypothetical protein 0.0035 0.0218 0.0225
Brugia malayi Pre-SET motif family protein 0.0095 0.0908 0.0936
Echinococcus granulosus tissue type plasminogen activator 0.0191 0.2014 0.3712
Loa Loa (eye worm) hypothetical protein 0.0857 0.9706 1
Brugia malayi F/Y-rich N-terminus family protein 0.0041 0.0285 0.0294
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0025 0.0103 0.0189
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0044 0.0322 0.0592
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.003 0.0158 0.0199
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0049 0.0377 0.0694
Brugia malayi EGF-like domain containing protein 0.0027 0.0126 0.013
Schistosoma mansoni hypothetical protein 0.003 0.0162 0.0162
Loa Loa (eye worm) latrophilin receptor protein 2 0.0061 0.0521 0.0537
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0037 0.0236 0.0436
Loa Loa (eye worm) hypothetical protein 0.0073 0.0653 0.0673
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0047 0.036 0.0663
Brugia malayi hypothetical protein 0.023 0.2471 0.2546
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0096 0.0923 0.5365
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.003 0.0158 0.0199
Echinococcus multilocularis Chromo domain 0.0025 0.0103 0.0189
Echinococcus granulosus jumonji domain containing protein 0.0129 0.13 0.2396
Entamoeba histolytica ubiquitin-conjugating enzyme family protein 0.0487 0.5427 1
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0103 0.0121
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.0653 0.0823
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0027 0.0126 0.0043
Trichomonas vaginalis Heterochromatin protein, putative 0.0025 0.0103 0.0121
Toxoplasma gondii histone lysine methyltransferase SET1 0.0049 0.0384 0.0707
Echinococcus granulosus chromobox protein 2 0.0025 0.0103 0.0189
Schistosoma mansoni protein phosphatase 2C 0.003 0.0158 0.0158
Toxoplasma gondii PHD-finger domain-containing protein 0.0093 0.0882 0.1625
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0355 0.0366
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.003 0.0158 0.0291
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0016 0.0002 0.0002
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0049 0.0377 0.0388
Echinococcus granulosus delta-like protein 1 0.0027 0.0126 0.0232
Loa Loa (eye worm) hypothetical protein 0.0069 0.0611 0.063
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0103 0.0189
Schistosoma mansoni hypothetical protein 0.0027 0.0126 0.0126
Leishmania major phosphatidylinositol 3-kinase, putative 0.0016 0.0002 0.0003
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0322 0.3524 0.6494
Schistosoma mansoni hypothetical protein 0.0027 0.0126 0.0126
Brugia malayi M-phase phosphoprotein, mpp8 0.0025 0.0103 0.0106
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0095 0.0908 0.0908
Schistosoma mansoni hypothetical protein 0.0027 0.0126 0.0126
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0037 0.0236 0.0236
Schistosoma mansoni hypothetical protein 0.0061 0.0521 0.0521
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0087 0.0812 0.4629
Echinococcus granulosus glycoprotein Antigen 5 0.0101 0.0973 0.1794
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0002 0.0002
Echinococcus multilocularis chromobox protein 1 0.0154 0.1584 0.2919
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0096 0.0923 0.1603
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0164 0.0194
Onchocerca volvulus 0.0069 0.0611 0.0548
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0037 0.0236 0.0244
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0025 0.0103 0.0103
Mycobacterium tuberculosis Conserved protein 0.0073 0.0653 0.107
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.003 0.0164 0.0194
Brugia malayi Protein kinase domain containing protein 0.0191 0.2014 0.2075
Echinococcus granulosus survival motor neuron protein 1 0.023 0.2471 0.4553
Echinococcus granulosus phd:f box containing protein 0.003 0.0158 0.0291
Toxoplasma gondii calcium binding egf domain-containing protein 0.0071 0.0633 0.1167
Echinococcus granulosus neuropeptide receptor A26 0.0381 0.4205 0.7748
Onchocerca volvulus 0.0069 0.0611 0.0548
Loa Loa (eye worm) jmjC domain-containing protein 0.003 0.0158 0.0163
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0064 0.0551 0.1015
Toxoplasma gondii ABC1 family protein 0.0073 0.0653 0.1204
Echinococcus granulosus CREB binding protein 0.0051 0.0404 0.0744
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0073 0.0653 0.0673
Schistosoma mansoni hypothetical protein 0.0133 0.1343 0.1343
Loa Loa (eye worm) hypothetical protein 0.0027 0.0126 0.013
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0025 0.0103 0.0103
Loa Loa (eye worm) jmjC domain-containing protein 0.003 0.0158 0.0163
Brugia malayi EGF-like domain containing protein 0.0027 0.0126 0.013
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0232 0.0274
Mycobacterium tuberculosis Probable hydrolase 0.0073 0.0653 0.107
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0101 0.0973 0.1794
Echinococcus multilocularis neuropeptide receptor A26 0.0381 0.4205 0.7748
Schistosoma mansoni notch 0.0027 0.0126 0.0126
Loa Loa (eye worm) PHD-finger family protein 0.0093 0.0882 0.0908
Plasmodium falciparum JmjC domain-containing protein, putative 0.003 0.0158 0.0291
Loa Loa (eye worm) hypothetical protein 0.0067 0.0591 0.0609
Echinococcus multilocularis notch 0.0027 0.0126 0.0232
Echinococcus granulosus protein jagged 1 0.0027 0.0126 0.0232
Trichomonas vaginalis alpha-glucosidase, putative 0.0082 0.0755 0.0892
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0025 0.0103 0.0103
Loa Loa (eye worm) hypothetical protein 0.0084 0.0782 0.0806
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0027 0.0126 0.013
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0026 0.0118 0.0118
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0049 0.0377 0.0694
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0084 0.0782 0.0806
Loa Loa (eye worm) TK/ROR protein kinase 0.0191 0.2014 0.2075
Echinococcus multilocularis voltage gated potassium channel 0.0019 0.0027 0.0049
Mycobacterium leprae conserved hypothetical protein 0.0073 0.0653 0.3583
Loa Loa (eye worm) hypothetical protein 0.0019 0.0027 0.0027
Loa Loa (eye worm) DOMON domain-containing protein 0.0069 0.0611 0.063
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0025 0.0103 0.0106
Echinococcus multilocularis cpg binding protein 0.0025 0.01 0.0184
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0073 0.0653 0.3583
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0091 0.0862 0.1588
Schistosoma mansoni jumonji domain containing protein 0.0241 0.2594 0.2594
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0087 0.0812 0.1383
Loa Loa (eye worm) hypothetical protein 0.0027 0.0126 0.013
Schistosoma mansoni cercarial elastase (S01 family) 0.0101 0.0973 0.0973
Brugia malayi Cadherin domain containing protein 0.0027 0.0126 0.013
Loa Loa (eye worm) hypothetical protein 0.0047 0.036 0.0371
Loa Loa (eye worm) hypothetical protein 0.0157 0.1618 0.1668
Entamoeba histolytica hypothetical protein 0.0026 0.011 0.0203
Schistosoma mansoni phosphatidylserine receptor 0.003 0.0158 0.0158
Loa Loa (eye worm) CXXC zinc finger family protein 0.0024 0.0084 0.0087
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0101 0.0973 0.0973
Trypanosoma cruzi Enriched in surface-labeled proteome protein 12 0.0704 0.7935 1
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0026 0.011 0.0014
Echinococcus granulosus lysosomal alpha glucosidase 0.0366 0.4037 0.7439
Schistosoma mansoni notch 0.0027 0.0126 0.0126
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0377 0.0445
Schistosoma mansoni hypothetical protein 0.0101 0.0973 0.0973
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0026 0.011 0.0203
Toxoplasma gondii thioredoxin reductase 0.0038 0.0251 0.0462
Echinococcus granulosus Chromobox protein 3 0.0025 0.0103 0.0189
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0261 0.0309
Schistosoma mansoni voltage-gated potassium channel 0.007 0.0619 0.0619
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0095 0.0908 0.1673
Trypanosoma brucei Enriched in surface-labeled proteome protein 12 0.0704 0.7935 1
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0136 0.016
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0659 0.7413 0.7638
Echinococcus granulosus protein jagged 2 0.0027 0.0126 0.0232
Echinococcus granulosus CREB binding protein 0.0083 0.0771 0.142
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0039 0.0262 0.0483
Echinococcus granulosus JmjC domain containing protein 4 0.003 0.0158 0.0291
Trichomonas vaginalis esterase, putative 0.0073 0.0653 0.0772
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0047 0.036 0.0454
Loa Loa (eye worm) hypothetical protein 0.0027 0.0126 0.013
Echinococcus granulosus neural cadherin 0.0027 0.0126 0.0232
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0126 0.1268 0.2337
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0073 0.0653 0.107
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0061 0.0521 0.096
Onchocerca volvulus 0.0073 0.0653 0.0592
Loa Loa (eye worm) jmjC domain-containing protein 0.0191 0.202 0.2081
Echinococcus multilocularis neurogenic locus protein delta 0.0027 0.0126 0.0232
Onchocerca volvulus 0.0092 0.0871 0.0818
Echinococcus multilocularis PHD finger protein rhinoceros 0.0093 0.0882 0.1625
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0047 0.036 0.0287
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0047 0.036 0.0454
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0303 0.3314 0.6107
Echinococcus multilocularis lysosomal alpha glucosidase 0.0366 0.4037 0.7439
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0061 0.0521 0.096
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0082 0.0755 0.0892
Trichomonas vaginalis glycogen debranching enzyme, putative 0.0157 0.1618 0.1912
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0025 0.0103 0.0189
Loa Loa (eye worm) hypothetical protein 0.0191 0.2014 0.2075
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0016 0.0002 0.0002
Brugia malayi TAZ zinc finger family protein 0.0083 0.0771 0.0794
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0096 0.0923 0.1603
Leishmania major hypothetical protein, conserved 0.0191 0.2014 0.3712
Loa Loa (eye worm) hypothetical protein 0.0101 0.0973 0.1003
Trichomonas vaginalis alpha-glucosidase, putative 0.0047 0.036 0.0425
Giardia lamblia PHD finger protein 15 0.0093 0.0882 0.2502
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0002 0.0002
Plasmodium vivax JmjC domain containing protein 0.003 0.0158 0.0104
Trichomonas vaginalis penicillin-binding protein, putative 0.0073 0.0653 0.0772
Giardia lamblia 4-alpha-glucanotransferase, amylo-alpha-1,6-glucosidase 0.0157 0.1618 0.4593
Loa Loa (eye worm) jmjC domain-containing protein 0.003 0.0158 0.0163
Brugia malayi EGF-like domain containing protein 0.0027 0.0126 0.013
Leishmania major hypothetical protein, conserved 0.003 0.0158 0.0291
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0322 0.3524 0.4164
Mycobacterium tuberculosis Probable esterase LipL 0.0073 0.0653 0.107
Trichomonas vaginalis alpha-glucosidase, putative 0.0082 0.0755 0.0892
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0194 0.2051 0.2113
Loa Loa (eye worm) hypothetical protein 0.0025 0.0103 0.0106
Loa Loa (eye worm) CBP-B 0.0058 0.0478 0.0492
Echinococcus granulosus neurogenic locus protein delta 0.0027 0.0126 0.0232
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0261 0.0309
Trichomonas vaginalis maltase-glucoamylase, putative 0.0082 0.0755 0.0892
Onchocerca volvulus 0.0191 0.2014 0.2006
Brugia malayi Glycosyl hydrolases family 31 protein 0.0047 0.036 0.0371
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0095 0.0908 0.0908
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0113 0.1122 0.1122
Echinococcus multilocularis neurogenic locus notch protein 4 0.0027 0.0126 0.0232
Toxoplasma gondii EGF family domain-containing protein 0.0027 0.0126 0.0232
Trypanosoma cruzi Enriched in surface-labeled proteome protein 12 0.0704 0.7935 1
Echinococcus granulosus glycogen debranching enzyme 0.0157 0.1618 0.2982
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0037 0.0236 0.0436
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0179 0.0211
Schistosoma mansoni hypothetical protein 0.0061 0.0521 0.0521
Brugia malayi beta-lactamase family protein 0.0073 0.0653 0.0673
Schistosoma mansoni cercarial elastase (S01 family) 0.0101 0.0973 0.0973
Brugia malayi Trypsin-like protease protein 5 0.0101 0.0973 0.1003
Onchocerca volvulus 0.0332 0.3642 0.3698
Brugia malayi CHD4 protein 0.0026 0.0118 0.0122
Plasmodium vivax SET domain protein, putative 0.0095 0.0908 0.1513
Trichomonas vaginalis set domain proteins, putative 0.075 0.8463 1
Trypanosoma cruzi target of rapamycin kinase 3 0.0039 0.0262 0.033
Loa Loa (eye worm) hypothetical protein 0.0027 0.0126 0.013
Loa Loa (eye worm) hypothetical protein 0.0027 0.0126 0.013
Trypanosoma cruzi hypothetical protein, conserved 0.0082 0.0755 0.0951
Echinococcus granulosus lysine specific demethylase 6a 0.003 0.0158 0.0291
Schistosoma mansoni hypothetical protein 0.0201 0.2134 0.2134
Brugia malayi Trypsin family protein 0.0101 0.0973 0.1003
Echinococcus granulosus notch 0.0027 0.0126 0.0232
Echinococcus granulosus peregrin 0.0094 0.0898 0.1656
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0049 0.0377 0.0475
Brugia malayi Calcium binding EGF domain containing protein 0.0027 0.0126 0.013
Schistosoma mansoni cercarial elastase (S01 family) 0.0101 0.0973 0.0973
Schistosoma mansoni notch 0.0027 0.0126 0.0126
Loa Loa (eye worm) hypothetical protein 0.0071 0.0633 0.0653
Plasmodium falciparum cysteine repeat modular protein 1 0.0191 0.2014 0.3712
Brugia malayi EGF-like domain containing protein 0.0027 0.0126 0.013
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0037 0.0236 0.0436
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0095 0.0908 0.1673
Loa Loa (eye worm) hypothetical protein 0.0133 0.1343 0.1383
Echinococcus granulosus dnaJ subfamily B 0.0335 0.3678 0.6778
Schistosoma mansoni CREB-binding protein 1 (SmCBP1) 0.0083 0.0771 0.0771
Schistosoma mansoni notch 0.0027 0.0126 0.0126
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0093 0.0882 0.0882
Onchocerca volvulus 0.0025 0.0103 0.0019
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0117 0.0138
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0487 0.5427 0.5591
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0103 0.0121
Echinococcus granulosus laminin 0.0071 0.0633 0.1167
Loa Loa (eye worm) hypothetical protein 0.023 0.2471 0.2546
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0049 0.0377 0.0694
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0061 0.0521 0.096
Echinococcus granulosus lysine specific demethylase 5A 0.0113 0.1122 0.2068
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0117 0.0138
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0038 0.0251 0.0277
Schistosoma mansoni hypothetical protein 0.0027 0.0126 0.0126
Brugia malayi Heterochromatin protein 1 0.0154 0.1584 0.1632
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0101 0.0973 0.0973
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0232 0.0274
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0487 0.5427 0.6839
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0002 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0117 0.0139
Echinococcus multilocularis slit 2 protein 0.0027 0.0126 0.0232
Loa Loa (eye worm) heterochromatin protein 1 0.0154 0.1584 0.1632
Giardia lamblia GTOR 0.0049 0.0377 0.1069
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.0084 0.0779 0.0802
Echinococcus multilocularis ubiquitin conjugating enzyme E2 N 0.0487 0.5427 1
Onchocerca volvulus 0.0035 0.022 0.0141
Brugia malayi PHD-finger family protein 0.0032 0.0178 0.0183
Echinococcus multilocularis enteropeptidase 0.0101 0.0973 0.1794
Trichomonas vaginalis alpha-glucosidase, putative 0.0082 0.0755 0.0892
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0093 0.0881 0.0828
Brugia malayi beta-lactamase family protein 0.0073 0.0653 0.0673
Brugia malayi chromobox protein homolog 3 0.0086 0.0806 0.083
Echinococcus multilocularis neural cadherin 0.0027 0.0126 0.0232
Trichomonas vaginalis alpha-glucosidase, putative 0.0047 0.036 0.0425
Loa Loa (eye worm) hypothetical protein 0.0857 0.9706 1
Brugia malayi latrophilin 2 splice variant baaae 0.0133 0.1343 0.1383
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0095 0.0908 0.1673
Mycobacterium tuberculosis Probable lipase LipE 0.0073 0.0653 0.107
Schistosoma mansoni cell polarity protein 0.0027 0.0126 0.0126
Mycobacterium tuberculosis Probable reductase 0.0087 0.0812 0.1383
Trichomonas vaginalis conserved hypothetical protein 0.0086 0.0806 0.0952
Schistosoma mansoni hypothetical protein 0.0025 0.0103 0.0103
Leishmania major hypothetical protein, conserved 0.0073 0.0653 0.1204
Brugia malayi jmjC domain containing protein 0.0113 0.1122 0.1156
Onchocerca volvulus 0.0073 0.0653 0.0592
Entamoeba histolytica hypothetical protein 0.0025 0.0103 0.0189
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0002 0.0002
Echinococcus multilocularis glycoprotein Antigen 5 0.0101 0.0973 0.1794
Mycobacterium ulcerans lipase LipD 0.0073 0.0653 0.3583
Schistosoma mansoni egf-like domain protein 0.0071 0.0633 0.0633
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0087 0.0812 0.1383
Giardia lamblia High cysteine protein 0.0027 0.0126 0.0357
Trypanosoma brucei hypothetical protein, conserved 0.0026 0.011 0.0139
Echinococcus granulosus beta LACTamase domain containing family member 0.0073 0.0653 0.1204
Toxoplasma gondii target of rapamycin (TOR), putative 0.0036 0.0232 0.0428
Loa Loa (eye worm) hypothetical protein 0.0039 0.0262 0.027
Brugia malayi Ubiquitin conjugating enzyme protein 13 0.0487 0.5427 0.5591
Trichomonas vaginalis chromobox protein, putative 0.0154 0.1584 0.1872
Brugia malayi Calcium binding EGF domain containing protein 0.0027 0.0126 0.013
Echinococcus multilocularis jumonji domain containing protein 0.0129 0.13 0.2396
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0019 0.0027 0.0049
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0026 0.011 0.5
Brugia malayi Thioredoxin reductase 0.0038 0.0251 0.0258
Schistosoma mansoni cercarial elastase (S01 family) 0.0101 0.0973 0.0973
Loa Loa (eye worm) hypothetical protein 0.0025 0.0103 0.0106
Loa Loa (eye worm) hypothetical protein 0.004 0.0275 0.0283
Echinococcus multilocularis neurogenic locus notch protein 0.0027 0.0126 0.0232
Echinococcus multilocularis glycogen debranching enzyme 0.0157 0.1618 0.2982
Schistosoma mansoni alpha-glucosidase 0.0332 0.3642 0.3642
Loa Loa (eye worm) hypothetical protein 0.0097 0.0928 0.0956
Onchocerca volvulus 0.0757 0.8545 0.8794
Echinococcus multilocularis survival motor neuron protein 1 0.023 0.2471 0.4553
Echinococcus multilocularis Mastin 0.0101 0.0973 0.1794
Trypanosoma brucei hypothetical protein, conserved 0.0704 0.7935 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.0103 0.0106
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0103 0.0121
Trypanosoma cruzi Enriched in surface-labeled proteome protein 12 0.0704 0.7935 1
Plasmodium vivax glutathione reductase, putative 0.0038 0.0251 0.0278
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0194 0.2051 0.2113
Schistosoma mansoni cercarial elastase (S01 family) 0.0101 0.0973 0.0973
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0025 0.0103 0.0189
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0191 0.0226
Schistosoma mansoni hypothetical protein 0.0101 0.0973 0.0973
Toxoplasma gondii ubiquitin-conjugating enzyme subfamily protein 0.0487 0.5427 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0158 0.0163
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0857 0.9706 0.9706
Echinococcus granulosus transmembrane protease serine 3 0.0101 0.0973 0.1794
Mycobacterium ulcerans beta-lactamase 0.0073 0.0653 0.3583
Echinococcus multilocularis JmjC domain containing protein 4 0.003 0.0158 0.0291
Schistosoma mansoni cercarial elastase (S01 family) 0.0101 0.0973 0.0973
Echinococcus multilocularis lysine specific demethylase 6a 0.003 0.0158 0.0291
Plasmodium vivax hypothetical protein, conserved 0.0032 0.0179 0.0143
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0157 0.1626 1
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0049 0.0377 0.0694
Onchocerca volvulus Neurogenic locus notch homolog 0.0027 0.0126 0.0043
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0049 0.0377 0.0475
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.003 0.0158 0.0199
Trichomonas vaginalis penicillin-binding protein, putative 0.0073 0.0653 0.0772
Brugia malayi Trypsin family protein 0.0101 0.0973 0.1003
Schistosoma mansoni hypothetical protein 0.0191 0.2014 0.2014
Giardia lamblia Fructose-bisphosphate aldolase 0.0322 0.3524 1
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0082 0.0755 0.0892
Brugia malayi Kringle domain containing protein 0.0191 0.2014 0.2075
Schistosoma mansoni aldehyde dehydrogenase 0.0126 0.1268 0.1268
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0103 0.0121
Loa Loa (eye worm) hypothetical protein 0.0027 0.0126 0.013
Leishmania major glycosyl hydrolase-like protein 0.0047 0.036 0.0663
Loa Loa (eye worm) hypothetical protein 0.0093 0.0882 0.0908
Schistosoma mansoni septate junction protein 0.0027 0.0126 0.0126
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0101 0.0973 0.1794
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0047 0.036 0.0425
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0101 0.0973 0.1003
Loa Loa (eye worm) hypothetical protein 0.0073 0.0653 0.0673
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0232 0.0274
Trypanosoma brucei hypothetical protein, conserved 0.0073 0.0653 0.0823
Brugia malayi AF-10 protein 0.003 0.0162 0.0167
Loa Loa (eye worm) hypothetical protein 0.0073 0.0653 0.0673
Schistosoma mansoni cercarial elastase (S01 family) 0.0101 0.0973 0.0973
Schistosoma mansoni cercarial elastase (S01 family) 0.0101 0.0973 0.0973
Onchocerca volvulus 0.075 0.8463 0.8708
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.015 0.0177
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.0071 0.0633 0.0653
Loa Loa (eye worm) hypothetical protein 0.0159 0.1645 0.1695
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0026 0.0118 0.0218
Brugia malayi Glycosyl hydrolases family 31 protein 0.0366 0.4037 0.4159
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0026 0.0118 0.0218
Trichomonas vaginalis sucrase-isomaltase, putative 0.0082 0.0755 0.0892
Schistosoma mansoni alpha glucosidase 0.0082 0.0755 0.0755
Onchocerca volvulus Alhambra homolog 0.0093 0.0882 0.0829
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0086 0.0806 0.075
Echinococcus granulosus GPCR family 2 0.0061 0.0521 0.096
Trichomonas vaginalis chromobox protein, putative 0.0093 0.0881 0.1041
Echinococcus multilocularis lysosomal alpha glucosidase 0.0366 0.4037 0.7439
Loa Loa (eye worm) hypothetical protein 0.0194 0.2051 0.2113
Entamoeba histolytica glycogen debranching enzyme, putative 0.0157 0.1618 0.2982
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0044 0.0322 0.0592
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0322 0.3524 0.4164
Loa Loa (eye worm) hypothetical protein 0.0035 0.022 0.0226
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0164 0.0194
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0146 0.0173
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0103 0.0121
Schistosoma mansoni hypothetical protein 0.0047 0.0355 0.0355
Loa Loa (eye worm) hypothetical protein 0.0027 0.0126 0.013
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0064 0.0551 0.1015
Schistosoma mansoni lipoxygenase 0.0044 0.0322 0.0322
Onchocerca volvulus Arrow homolog 0.0084 0.0779 0.0722
Trichomonas vaginalis glycogen debranching enzyme, putative 0.0157 0.1618 0.1912
Plasmodium vivax hypothetical protein, conserved 0.0073 0.0653 0.1034
Loa Loa (eye worm) jmjC domain-containing protein 0.0113 0.1122 0.1156
Echinococcus multilocularis neurogenic locus notch protein 0.0027 0.0126 0.0232
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.006 0.0502 0.0594
Echinococcus multilocularis protein jagged 1 0.0027 0.0126 0.0232
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0073 0.0653 0.0673
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0016 0.0002 0.0003
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0087 0.0812 0.1383
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0016 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0101 0.0973 0.1003
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0095 0.0908 0.0908
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0164 0.0194
Onchocerca volvulus 0.0101 0.0973 0.0924
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0103 0.0121
Loa Loa (eye worm) hypothetical protein 0.0027 0.0126 0.013
Schistosoma mansoni survival motor neuron protein 0.0047 0.0355 0.0355
Loa Loa (eye worm) hypothetical protein 0.0027 0.0126 0.013
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0322 0.3524 0.4164
Trichomonas vaginalis chromobox protein, putative 0.0093 0.0881 0.1041
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0061 0.0521 0.0537
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0037 0.0236 0.0436
Loa Loa (eye worm) hypothetical protein 0.0073 0.0653 0.0673
Loa Loa (eye worm) hypothetical protein 0.0027 0.0126 0.013
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0016 0.0002 0.0003
Mycobacterium tuberculosis Conserved protein 0.0073 0.0653 0.107
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0103 0.0121
Echinococcus granulosus neuropeptide s receptor 0.0381 0.4205 0.7748
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0037 0.0236 0.0244
Plasmodium falciparum heterochromatin protein 1 0.0025 0.0103 0.0189
Loa Loa (eye worm) hypothetical protein 0.0025 0.0103 0.0106
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0047 0.036 0.0425
Schistosoma mansoni hypothetical protein 0.0113 0.1117 0.1117
Trypanosoma cruzi Enriched in surface-labeled proteome protein 12 0.0704 0.7935 1
Echinococcus granulosus chromobox protein 1 0.0154 0.1584 0.2919
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0073 0.0653 0.107
Schistosoma mansoni hypothetical protein 0.0027 0.0126 0.0126
Onchocerca volvulus 0.0027 0.0126 0.0043
Schistosoma mansoni cellular tumor antigen P53 0.0035 0.022 0.022
Plasmodium vivax thioredoxin reductase, putative 0.0038 0.0251 0.0278
Brugia malayi Bromodomain containing protein 0.0094 0.0898 0.0926
Loa Loa (eye worm) hypothetical protein 0.0073 0.0653 0.0673
Echinococcus multilocularis transmembrane protease serine 3 0.0101 0.0973 0.1794
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.0084 0.0779 0.0802
Echinococcus granulosus neutral alpha glucosidase AB 0.0082 0.0755 0.1391
Loa Loa (eye worm) hypothetical protein 0.003 0.0158 0.0163
Trypanosoma brucei ubiquitin-protein ligase, putative 0.0487 0.5427 0.6839
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0092 0.0871 0.0897
Echinococcus multilocularis CREB binding protein 0.0057 0.047 0.0865
Loa Loa (eye worm) hypothetical protein 0.0071 0.0633 0.0653
Brugia malayi Delta serrate ligand family protein 0.0027 0.0126 0.013
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0261 0.0309
Schistosoma mansoni jumonji/arid domain-containing protein 0.0113 0.1122 0.1122
Schistosoma mansoni jumonji/arid domain-containing protein 0.0113 0.1122 0.1122
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0117 0.0139
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0092 0.0871 0.0871
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.006 0.0502 0.0594
Onchocerca volvulus 0.0067 0.0591 0.0527
Echinococcus multilocularis beta LACTamase domain containing family member 0.0073 0.0653 0.1204
Echinococcus multilocularis protein jagged 2 0.0027 0.0126 0.0232
Echinococcus multilocularis fibrillin 1 0.0071 0.0633 0.1167
Leishmania major phosphopantetheinyl transferase-like protein 0.0026 0.011 0.0203
Echinococcus granulosus Chromo domain 0.0025 0.0103 0.0189
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.0653 0.0772
Echinococcus granulosus L aminoadipate semialdehyde 0.0092 0.0871 0.1605
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0157 0.1626 0.2987
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.0653 0.0823
Loa Loa (eye worm) hypothetical protein 0.0092 0.0871 0.0897
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0126 0.1268 0.2337
Echinococcus granulosus chromobox protein 1 0.0154 0.1584 0.2919
Trypanosoma brucei glycosyl hydrolase-like protein 0.0047 0.036 0.0454
Loa Loa (eye worm) hypothetical protein 0.0027 0.0126 0.013
Echinococcus multilocularis L aminoadipate semialdehyde 0.0092 0.0871 0.1605
Echinococcus multilocularis dnaJ subfamily B 0.0335 0.3678 0.6778
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0028 0.0136 0.016
Trypanosoma cruzi hypothetical protein, conserved 0.0082 0.0755 0.0951
Schistosoma mansoni laminin gamma-3 chain 0.0027 0.0126 0.0126
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0027 0.0027
Echinococcus multilocularis fibropellin Ia 0.0027 0.0126 0.0232
Schistosoma mansoni chromobox protein 0.0025 0.0103 0.0103
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0025 0.0103 0.0189
Brugia malayi EGF-like domain containing protein 0.0027 0.0126 0.013
Schistosoma mansoni cercarial elastase (S01 family) 0.0101 0.0973 0.0973
Mycobacterium tuberculosis Probable lipase LipD 0.0073 0.0653 0.107
Echinococcus granulosus ubiquitin conjugating enzyme E2 N 0.0487 0.5427 1
Onchocerca volvulus Slit protein homolog 0.0027 0.0126 0.0043
Loa Loa (eye worm) transcription factor SMAD2 0.0098 0.0941 0.0969
Loa Loa (eye worm) Notch2 0.0027 0.0126 0.013
Loa Loa (eye worm) MH2 domain-containing protein 0.0098 0.0941 0.0969
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0082 0.0755 0.1391
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0037 0.0236 0.0236
Schistosoma mansoni cercarial elastase (S01 family) 0.0101 0.0973 0.0973
Brugia malayi Calcium binding EGF domain containing protein 0.0071 0.0633 0.0653
Trichomonas vaginalis chromobox protein, putative 0.0025 0.0103 0.0121
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0322 0.3524 0.4164
Loa Loa (eye worm) hypothetical protein 0.0027 0.0126 0.013
Brugia malayi SET domain containing protein 0.0029 0.0149 0.0153
Echinococcus granulosus PHD finger protein rhinoceros 0.0093 0.0882 0.1625
Schistosoma mansoni hypothetical protein 0.0069 0.0611 0.0611
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0117 0.0139
Echinococcus granulosus enteropeptidase 0.0101 0.0973 0.1794
Loa Loa (eye worm) hypothetical protein 0.0027 0.0126 0.013
Onchocerca volvulus 0.0069 0.0611 0.0548
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0157 0.1626 1
Onchocerca volvulus Putative cubilin 0.004 0.0275 0.0198
Mycobacterium tuberculosis Probable oxidoreductase 0.0096 0.0923 0.1603
Brugia malayi ubiquitin conjugating enzyme protein 13 0.0487 0.5427 0.5591
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0002 0.0002
Brugia malayi CUB domain containing protein 0.0026 0.0107 0.011
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.0653 0.0772
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0064 0.0551 0.0568
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0322 0.3524 0.4164
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0025 0.0103 0.0189
Schistosoma mansoni cpg binding protein 0.0025 0.01 0.01
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0082 0.0755 0.1391
Loa Loa (eye worm) hypothetical protein 0.0027 0.0126 0.013
Loa Loa (eye worm) hypothetical protein 0.0027 0.0126 0.013
Trichomonas vaginalis alpha-glucosidase, putative 0.0082 0.0755 0.0892
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0146 0.0173
Echinococcus granulosus protein jagged 1 0.0027 0.0126 0.0232
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0103 0.0121
Schistosoma mansoni hypothetical protein 0.0027 0.0126 0.0126
Mycobacterium ulcerans aldehyde dehydrogenase 0.0126 0.1268 0.7641
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0164 0.0194
Loa Loa (eye worm) hypothetical protein 0.0027 0.0126 0.013
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0025 0.0103 0.0189
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0322 0.3524 0.4164
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0082 0.0755 0.0778
Schistosoma mansoni hypothetical protein 0.0093 0.0882 0.0882
Loa Loa (eye worm) phosphatidylinositol 3 0.0049 0.0377 0.0388
Echinococcus granulosus neurogenic locus notch protein 0.0027 0.0126 0.0232
Loa Loa (eye worm) beta-lactamase 0.0073 0.0653 0.0673
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.003 0.0164 0.0194
Loa Loa (eye worm) hypothetical protein 0.0096 0.0924 0.0952
Echinococcus granulosus Mastin 0.0101 0.0973 0.1794
Echinococcus granulosus protein jagged 2 0.0027 0.0126 0.0232
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0366 0.4037 0.4159
Brugia malayi Trypsin family protein 0.0857 0.9706 1
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.003 0.0162 0.0204
Echinococcus granulosus neurogenic locus notch protein 4 0.0027 0.0126 0.0232
Brugia malayi Associated with TFs and helicases family protein 0.0025 0.0103 0.0106
Schistosoma mansoni alpha-glucosidase 0.0332 0.3642 0.3642
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0037 0.0236 0.0236
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0103 0.0121
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0103 0.0189
Trichomonas vaginalis conserved hypothetical protein 0.008 0.0739 0.0874
Schistosoma mansoni ubiquitin conjugating enzyme 13 0.0487 0.5427 0.5427
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0049 0.0377 0.0475
Echinococcus granulosus voltage gated potassium channel 0.0019 0.0027 0.0049
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0061 0.0521 0.096
Echinococcus granulosus jumonji domain containing 1A 0.003 0.0158 0.0291
Onchocerca volvulus 0.0857 0.9706 1
Plasmodium vivax hypothetical protein, conserved 0.0025 0.0103 0.00000000014506
Loa Loa (eye worm) hypothetical protein 0.0027 0.0126 0.013
Brugia malayi EGF-like domain containing protein 0.0027 0.0126 0.013
Brugia malayi jmjC domain containing protein 0.003 0.0158 0.0163
Loa Loa (eye worm) hypothetical protein 0.0032 0.0178 0.0183
Echinococcus granulosus Tolloid protein 1 0.0084 0.0782 0.1441
Schistosoma mansoni mixed-lineage leukemia protein mll 0.004 0.027 0.027
Brugia malayi Amylo-alpha-1,6-glucosidase family protein 0.0157 0.1618 0.1668
Loa Loa (eye worm) hypothetical protein 0.0025 0.0103 0.0106
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0164 0.0194
Mycobacterium ulcerans hypothetical protein 0.0073 0.0653 0.3583
Trichomonas vaginalis maltase-glucoamylase, putative 0.0047 0.036 0.0425
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0487 0.5427 0.6839
Brugia malayi Latrophilin receptor protein 2 0.0061 0.0521 0.0537
Loa Loa (eye worm) hypothetical protein 0.0101 0.0973 0.1003
Trichomonas vaginalis conserved hypothetical protein 0.0086 0.0806 0.0952
Echinococcus multilocularis neuropeptide s receptor 0.0381 0.4205 0.7748
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0101 0.0973 0.1794
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0232 0.0274
Loa Loa (eye worm) thioredoxin reductase 0.0038 0.0251 0.0258
Schistosoma mansoni cpg binding protein 0.0025 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0084 0.0779 0.0802
Loa Loa (eye worm) hypothetical protein 0.0025 0.0103 0.0106
Loa Loa (eye worm) hypothetical protein 0.0056 0.0453 0.0467
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0232 0.0274
Brugia malayi Protein cec-1. 0.0025 0.0103 0.0106
Mycobacterium ulcerans hypothetical protein 0.0101 0.0973 0.5695
Schistosoma mansoni cpg binding protein 0.0024 0.0084 0.0084
Echinococcus multilocularis jumonji domain containing 1A 0.003 0.0158 0.0291
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0026 0.011 0.0203
Loa Loa (eye worm) hypothetical protein 0.0101 0.0973 0.1003
Onchocerca volvulus 0.0101 0.0973 0.0924
Brugia malayi jmjC domain containing protein 0.003 0.0158 0.0163
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.015 0.0177
Loa Loa (eye worm) trypsin family protein 0.0101 0.0973 0.1003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0377 0.0445
Echinococcus multilocularis neurogenic locus protein delta 0.0027 0.0126 0.0232
Loa Loa (eye worm) hypothetical protein 0.0027 0.0126 0.013
Loa Loa (eye worm) helicase 0.0025 0.0103 0.0106
Loa Loa (eye worm) CHromoDomain protein family member 0.0026 0.0118 0.0122
Onchocerca volvulus 0.0027 0.0126 0.0043
Onchocerca volvulus 0.0101 0.0973 0.0924
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0016 0.0002 0.0002
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0087 0.0812 0.1383
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.0516 0.0609
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0101 0.0973 0.1794
Brugia malayi beta-lactamase 0.0073 0.0653 0.0673
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0049 0.0377 0.0694
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.015 0.0177
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0032 0.0179 0.0329
Plasmodium vivax ubiquitin-conjugating enzyme E2 N, putative 0.0487 0.5427 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0232 0.0274
Schistosoma mansoni jumonji domain containing protein 0.003 0.0158 0.0158
Echinococcus multilocularis fat cadherin tumor suppressor 0.0027 0.0126 0.0232
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0031 0.0173 0.0319
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0322 0.3524 0.4164
Trypanosoma cruzi Enriched in surface-labeled proteome protein 12 0.0704 0.7935 1
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0103 0.0121
Trichomonas vaginalis alpha-glucosidase, putative 0.0047 0.036 0.0425
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0322 0.3524 0.6494
Echinococcus multilocularis phd:f box containing protein 0.003 0.0158 0.0291
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0049 0.0377 0.0694
Loa Loa (eye worm) hypothetical protein 0.0086 0.0806 0.083
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0027 0.0027
Schistosoma mansoni chromobox protein 0.0025 0.0103 0.0103
Echinococcus multilocularis chromobox protein 2 0.0025 0.0103 0.0189
Brugia malayi Fibulin-1 precursor 0.0071 0.0633 0.0653
Loa Loa (eye worm) hypothetical protein 0.0027 0.0126 0.013
Brugia malayi notch-like transmembrane receptor 0.0027 0.0126 0.013
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0064 0.0551 0.0568
Brugia malayi CXXC zinc finger family protein 0.0024 0.0084 0.0087
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0322 0.3524 0.4164
Trichomonas vaginalis chromobox protein, putative 0.0025 0.0103 0.0121
Onchocerca volvulus 0.0069 0.0611 0.0548
Echinococcus multilocularis neutral alpha glucosidase AB 0.0082 0.0755 0.1391
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0101 0.0973 0.0973
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0162 0.0299
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.003 0.0158 0.0158
Trichomonas vaginalis chromobox protein, putative 0.0025 0.0103 0.0121
Loa Loa (eye worm) phosphatidylinositol 3 0.0016 0.0002 0.0002
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0303 0.3314 0.6107
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0073 0.0653 0.107
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0025 0.0103 0.0189
Brugia malayi jmjC domain containing protein 0.003 0.0158 0.0163
Toxoplasma gondii histone lysine demethylase JMJD6a 0.003 0.0158 0.0291
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.0653 0.0772
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0164 0.0194
Loa Loa (eye worm) hypothetical protein 0.0101 0.0973 0.1003
Plasmodium falciparum thioredoxin reductase 0.0038 0.0251 0.0462
Echinococcus multilocularis thioredoxin glutathione reductase 0.0038 0.0251 0.0462
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0084 0.0782 0.0782
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0019 0.0027 0.0027
Onchocerca volvulus 0.0101 0.0973 0.0924
Leishmania major trypanothione reductase 0.0038 0.0251 0.0462
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0073 0.0653 0.0653
Brugia malayi jmjC domain containing protein 0.003 0.0158 0.0163
Loa Loa (eye worm) hypothetical protein 0.0027 0.0126 0.013
Onchocerca volvulus 0.0025 0.0103 0.0019
Leishmania major ubiquitin-conjugating enzyme e2, putative 0.0487 0.5427 1
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.0516 0.0609
Echinococcus multilocularis Tolloid protein 1 0.0084 0.0782 0.1441
Schistosoma mansoni notch 0.0027 0.0126 0.0126
Loa Loa (eye worm) glutathione reductase 0.0038 0.0251 0.0258
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0031 0.0173 0.0319
Brugia malayi glutathione reductase 0.0038 0.0251 0.0258
Onchocerca volvulus 0.012 0.1198 0.1158
Schistosoma mansoni chromobox protein 0.0154 0.1584 0.1584
Trichomonas vaginalis alpha-glucosidase, putative 0.0082 0.0755 0.0892
Toxoplasma gondii PHD-finger domain-containing protein 0.0093 0.0882 0.1625
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0023 0.0079 0.01
Onchocerca volvulus 0.0096 0.0924 0.0873
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0487 0.5427 0.6413
Loa Loa (eye worm) notch protein 0.0027 0.0126 0.013
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0103 0.0121
Brugia malayi EGF-like domain containing protein 0.0027 0.0126 0.013
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0232 0.0274
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0049 0.0377 0.0475
Trichomonas vaginalis alpha-glucosidase, putative 0.0047 0.036 0.0425
Trypanosoma cruzi trypanothione reductase, putative 0.0038 0.0251 0.0316
Echinococcus multilocularis protein jagged 1 0.0027 0.0126 0.0232
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.012 0.1198 0.1198
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.003 0.0162 0.0204
Echinococcus granulosus cpg binding protein 0.0025 0.01 0.0184
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.002 0.0047 0.0059
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0028 0.0131 0.0155
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0016 0.0002 0.0002
Schistosoma mansoni CREB-binding protein 2 0.0083 0.0771 0.0771
Schistosoma mansoni cercarial elastase (S01 family) 0.0101 0.0973 0.0973
Loa Loa (eye worm) amylo-alpha-1,6-glucosidase 0.0076 0.0692 0.0713
Brugia malayi Calcium binding EGF domain containing protein 0.004 0.0275 0.0283
Trypanosoma brucei trypanothione reductase 0.0038 0.0251 0.0316
Onchocerca volvulus 0.0027 0.0126 0.0043
Mycobacterium ulcerans esterase/lipase LipP 0.0073 0.0653 0.3583
Trypanosoma cruzi hypothetical protein, conserved 0.0191 0.2014 0.2539
Schistosoma mansoni chromobox protein 0.0154 0.1584 0.1584
Loa Loa (eye worm) hypothetical protein 0.0095 0.0908 0.0936
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0016 0.0002 0.0003
Echinococcus multilocularis lysine specific demethylase 5A 0.0112 0.1107 0.2039
Brugia malayi PHD-finger family protein 0.0093 0.0882 0.0908
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0073 0.0653 0.0653
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0377 0.0445
Onchocerca volvulus 0.0027 0.0126 0.0043
Mycobacterium tuberculosis Conserved protein 0.0073 0.0653 0.107
Brugia malayi Cadherin domain containing protein 0.0027 0.0126 0.013
Echinococcus granulosus fibropellin Ia 0.0027 0.0126 0.0232
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0487 0.5427 0.6413
Brugia malayi Muscle positioning protein 4 0.0096 0.0924 0.0952
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0103 0.0189
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0049 0.0377 0.0377
Trichomonas vaginalis alpha-glucosidase, putative 0.0047 0.036 0.0425
Plasmodium falciparum phd finger protein, putative 0.0093 0.0882 0.1625
Mycobacterium ulcerans aldehyde dehydrogenase 0.0126 0.1268 0.7641
Loa Loa (eye worm) hypothetical protein 0.0061 0.0521 0.0537
Entamoeba histolytica hypothetical protein 0.0025 0.0103 0.0189
Echinococcus granulosus tumor protein p63 0.0241 0.2594 0.478
Brugia malayi Trypsin family protein 0.0101 0.0973 0.1003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0261 0.0309
Brugia malayi Valyl-tRNA synthetase 0.0025 0.0103 0.0106
Echinococcus granulosus thioredoxin glutathione reductase 0.0038 0.0251 0.0462
Brugia malayi hypothetical protein 0.0101 0.0973 0.1003
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0101 0.0973 0.0973
Onchocerca volvulus 0.0101 0.0973 0.0924
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0117 0.0139
Schistosoma mansoni notch 0.0027 0.0126 0.0126
Toxoplasma gondii aldehyde dehydrogenase 0.0126 0.1268 0.2337
Mycobacterium ulcerans aldehyde dehydrogenase 0.0126 0.1268 0.7641
Plasmodium falciparum ubiquitin-conjugating enzyme E2 N, putative 0.0487 0.5427 1
Loa Loa (eye worm) hypothetical protein 0.0073 0.0653 0.0673
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0016 0.0002 0.0002
Echinococcus multilocularis laminin 0.0071 0.0633 0.1167
Brugia malayi Glycosyl hydrolases family 31 protein 0.0082 0.0755 0.0778
Schistosoma mansoni voltage-gated potassium channel 0.007 0.0619 0.0619
Leishmania major alpha glucosidase II subunit, putative 0.0082 0.0755 0.1391
Toxoplasma gondii calcium binding egf domain-containing protein 0.0071 0.0633 0.1167
Toxoplasma gondii kringle domain-containing protein 0.0191 0.2014 0.3712
Mycobacterium tuberculosis Probable dehydrogenase 0.0087 0.0812 0.1383
Trichomonas vaginalis chromobox protein, putative 0.0154 0.1584 0.1872
Schistosoma mansoni aldehyde dehydrogenase 0.0126 0.1268 0.1268
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0487 0.5427 0.5591
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0465 0.5183 1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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