TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 520.92 | Formula: C33H68N4++++
H donors: 0 H acceptors: 0 LogP: 7.44 Rotable bonds: 20
Rule of 5 violations (Lipinski): 2
SMILES: CCCCCCCC[N+]12CC[N+](CC1)(CC2)CCCCC[N+]12CC[N+](CC1)(CC2)CCCCCCCC
InChi: 1S/C33H68N4/c1-3-5-7-9-11-14-18-34-22-28-36(29-23-34,30-24-34)20-16-13-17-21-37-31-25-35(26-32-37,27-33-37)19-15-12-10-8-6-4-2/h3-33H2,1-2H3/q+4
InChiKey: BCZZLBHGBORZCM-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Loa Loa (eye worm)	unidentified vitellogenin-linked transcript protein 6	0.0138	0.9992	0.9992
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0138	0.9992	1
Onchocerca volvulus	Dopamine\/Ecdysteroid receptor homolog	0.0138	0.9992	0.5
Loa Loa (eye worm)	RNA recognition domain-containing protein domain-containing protein	0.0063	0.3893	0.3876
Loa Loa (eye worm)	hypothetical protein	0.0138	0.9992	0.9992
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0138	0.9992	1
Echinococcus multilocularis	growth hormone secretagogue receptor type 1	0.0138	0.9992	1
Brugia malayi	hypothetical protein	0.0138	0.9992	0.9992
Echinococcus multilocularis	peptide (allatostatin:somatostatin)	0.0138	0.9992	1
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0138	0.9992	1
Brugia malayi	gonadotropin-releasing hormone receptor 2	0.0138	0.9992	0.9992
Onchocerca volvulus		0.0138	0.9992	0.5
Echinococcus multilocularis	neuropeptide Y receptor	0.0138	0.9992	1
Schistosoma mansoni	amine GPCR	0.0138	0.9992	1
Brugia malayi	Dopamine receptor	0.0138	0.9992	0.9992
Brugia malayi	neuropeptide F receptor	0.0138	0.9992	0.9992
Loa Loa (eye worm)	hypothetical protein	0.0138	0.9992	0.9992
Brugia malayi	Dopamine receptor protein 1	0.0138	0.9992	0.9992
Loa Loa (eye worm)	hypothetical protein	0.0138	0.9992	0.9992
Echinococcus multilocularis	g-protein coupled receptor	0.0138	0.9992	1
Loa Loa (eye worm)	hypothetical protein	0.0138	0.9992	0.9992
Loa Loa (eye worm)	hypothetical protein	0.0138	0.9992	0.9992
Brugia malayi	TAR-binding protein	0.0063	0.3893	0.3876
Loa Loa (eye worm)	follicle stimulating hormone receptor	0.0138	0.9992	0.9992
Loa Loa (eye worm)	hypothetical protein	0.0138	0.9992	0.9992
Echinococcus granulosus	rhodopsin orphan GPCR	0.0138	0.9992	1
Trypanosoma cruzi	DNA polymerase kappa, putative	0.0022	0.0565	0.5
Onchocerca volvulus		0.0138	0.9992	0.5
Onchocerca volvulus		0.0138	0.9992	0.5
Schistosoma mansoni	neuropeptide F-like receptor	0.0138	0.9992	1
Loa Loa (eye worm)	hypothetical protein	0.0138	0.9992	0.9992
Loa Loa (eye worm)	hypothetical protein	0.0138	0.9992	0.9992
Echinococcus multilocularis	allatostatin A receptor	0.0138	0.9992	1
Echinococcus multilocularis	neuropeptide receptor	0.0138	0.9992	1
Brugia malayi	Serotonin/octopamine receptor family protein 7	0.0138	0.9992	0.9992
Loa Loa (eye worm)	TAR-binding protein	0.0063	0.3893	0.3876
Schistosoma mansoni	peptide (FMRFamide/neurokinin-3)-like receptor	0.0138	0.9992	1
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0138	0.9992	1
Giardia lamblia	DINP protein human, muc B family	0.0022	0.0565	0.5
Echinococcus granulosus	g protein coupled receptor	0.0138	0.9992	1
Schistosoma mansoni	growth hormone secretagogue receptor	0.0138	0.9992	1
Onchocerca volvulus		0.0138	0.9992	0.5
Loa Loa (eye worm)	hypothetical protein	0.0138	0.9992	0.9992
Schistosoma mansoni	biogenic amine receptor	0.0138	0.9992	1
Brugia malayi	G protein-coupled receptor	0.0138	0.9992	0.9992
Loa Loa (eye worm)	hypothetical protein	0.0034	0.1515	0.1492
Loa Loa (eye worm)	hypothetical protein	0.0138	0.9992	0.9992
Schistosoma mansoni	biogenic amine receptor	0.0138	0.9992	1
Brugia malayi	hypothetical protein	0.0138	0.9992	0.9992
Echinococcus multilocularis	pyroglutamylated rfamide peptide receptor	0.0138	0.9992	1
Schistosoma mansoni	hypothetical protein	0.0138	0.9992	1
Echinococcus granulosus	pyroglutamylated rfamide peptide receptor	0.0138	0.9992	1
Echinococcus multilocularis	tachykinin peptides receptor 99D	0.0138	0.9992	1
Leishmania major	DNA polymerase kappa, putative,DNA polymerase IV, putative	0.0022	0.0565	0.5
Echinococcus granulosus	dna polymerase kappa	0.0022	0.0565	0.0539
Echinococcus granulosus	tachykinin peptides receptor 99D	0.0138	0.9992	1
Echinococcus granulosus	terminal deoxycytidyl transferase rev1	0.0022	0.0565	0.0539
Loa Loa (eye worm)	pigment dispersing factor receptor c	0.005	0.2796	0.2777
Echinococcus granulosus	allatostatin A receptor	0.0138	0.9992	1
Onchocerca volvulus		0.0138	0.9992	0.5
Loa Loa (eye worm)	hypothetical protein	0.0138	0.9992	0.9992
Brugia malayi	hypothetical protein	0.0138	0.9992	0.9992
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0138	0.9992	1
Schistosoma mansoni	neuropeptide receptor	0.0138	0.9992	1
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0138	0.9992	1
Echinococcus granulosus	neuropeptides capa receptor	0.0138	0.9992	1
Mycobacterium ulcerans	DNA polymerase IV	0.0022	0.0565	0.5
Loa Loa (eye worm)	hypothetical protein	0.0138	0.9992	0.9992
Loa Loa (eye worm)	hypothetical protein	0.0138	0.9992	0.9992
Brugia malayi	neuropeptide F receptor	0.0138	0.9992	0.9992
Echinococcus granulosus	rhodopsin orphan GPCR	0.0138	0.9992	1
Brugia malayi	larval opioid receptor	0.0138	0.9992	0.9992
Loa Loa (eye worm)	transcription factor SMAD2	0.0138	1	1
Brugia malayi	GTP-binding regulatory protein Gs alpha-S chain, putative	0.0046	0.2462	0.2442
Entamoeba histolytica	deoxycytidyl transferase, putative	0.0022	0.0565	0.5
Loa Loa (eye worm)	hypothetical protein	0.0138	0.9992	0.9992
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0138	0.9992	1
Echinococcus granulosus	neuropeptide receptor	0.0138	0.9992	1
Schistosoma mansoni	DNA polymerase eta	0.0022	0.0565	0.0539
Onchocerca volvulus		0.0138	0.9992	0.5
Echinococcus multilocularis	G-protein coupled receptor, putative	0.0138	0.9992	1
Schistosoma mansoni	biogenic amine (octopamine/dopamine) receptor	0.0138	0.9992	1
Echinococcus granulosus	neuropeptide Y receptor	0.0138	0.9992	1
Echinococcus multilocularis	fmrfamide receptor	0.0138	0.9992	1
Loa Loa (eye worm)	hypothetical protein	0.0138	0.9992	0.9992
Echinococcus granulosus	orexin receptor type 2	0.0138	0.9992	1
Echinococcus granulosus	tm gpcr rhodopsin	0.0138	0.9992	1
Loa Loa (eye worm)	hypothetical protein	0.0138	0.9992	0.9992
Schistosoma mansoni	neuropeptide receptor	0.0138	0.9992	1
Loa Loa (eye worm)	hypothetical protein	0.0138	0.9992	0.9992
Schistosoma mansoni	amine GPCR	0.0138	0.9992	1
Onchocerca volvulus		0.0138	0.9992	0.5
Loa Loa (eye worm)	hypothetical protein	0.0138	0.9992	0.9992
Echinococcus multilocularis	neuropeptide FF receptor 2	0.0138	0.9992	1
Echinococcus multilocularis	G protein coupled receptor 139	0.0138	0.9992	1
Brugia malayi	hypothetical protein	0.0138	0.9992	0.9992
Brugia malayi	putative neuropeptide receptor NPR1	0.0138	0.9992	0.9992
Schistosoma mansoni	tar DNA-binding protein	0.0063	0.3893	0.3879
Echinococcus multilocularis	neuropeptides capa receptor	0.0138	0.9992	1
Echinococcus multilocularis	serotonin receptor	0.0138	0.9992	1
Onchocerca volvulus		0.0138	0.9992	0.5
Brugia malayi	ImpB/MucB/SamB family protein	0.0022	0.0565	0.0539
Onchocerca volvulus		0.0138	0.9992	0.5
Echinococcus multilocularis	fmrfamide receptor	0.0138	0.9992	1
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0138	0.9992	1
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0138	0.9992	1
Echinococcus granulosus	somatostatin receptor	0.0138	0.9992	1
Brugia malayi	AKH receptor	0.0138	0.9992	0.9992
Brugia malayi	hypothetical protein	0.0138	0.9992	0.9992
Echinococcus granulosus	tm gpcr rhodopsin	0.0138	0.9992	1
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0138	0.9992	1
Schistosoma mansoni	hypothetical protein	0.0138	0.9992	1
Schistosoma mansoni	histamine h1 receptor	0.0138	0.9992	1
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0138	0.9992	1
Trypanosoma brucei	DNA polymerase kappa, putative	0.0022	0.0565	1
Echinococcus multilocularis	g protein coupled receptor	0.0138	0.9992	1
Brugia malayi	follicle stimulating hormone receptor	0.0138	0.9992	0.9992
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0046	0.2462	0.2444
Brugia malayi	RNA recognition motif domain containing protein	0.0063	0.3893	0.3876
Loa Loa (eye worm)	hypothetical protein	0.005	0.2796	0.2777
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0138	0.9992	1
Trichomonas vaginalis	DNA polymerase eta, putative	0.0022	0.0565	0.5
Echinococcus multilocularis	G protein coupled 5 hydroxytryptamine receptor	0.0138	0.9992	1
Loa Loa (eye worm)	neuropeptide F receptor	0.0138	0.9992	0.9992
Echinococcus granulosus	neuropeptide Y receptor	0.0138	0.9992	1
Echinococcus granulosus	neuropeptides capa receptor	0.0138	0.9992	1
Loa Loa (eye worm)	hypothetical protein	0.0138	0.9992	0.9992
Onchocerca volvulus		0.0138	0.9992	0.5
Loa Loa (eye worm)	TYRA-2 protein	0.0138	0.9992	0.9992
Echinococcus granulosus	peptide allatostatin:somatostatin	0.0138	0.9992	1
Echinococcus multilocularis	dna polymerase kappa	0.0022	0.0565	0.0539
Loa Loa (eye worm)	hypothetical protein	0.0138	0.9992	0.9992
Loa Loa (eye worm)	hypothetical protein	0.0138	0.9992	0.9992
Echinococcus multilocularis	somatostatin receptor	0.0138	0.9992	1
Brugia malayi	G-protein coupled receptor	0.0138	0.9992	0.9992
Loa Loa (eye worm)	G-protein coupled receptor	0.0138	0.9992	0.9992
Trichomonas vaginalis	DNA polymerase IV / kappa, putative	0.0022	0.0565	0.5
Loa Loa (eye worm)	5-hydroxytryptamine 2C receptor	0.0138	0.9992	0.9992
Echinococcus multilocularis	dro:myosuppressin receptor	0.0138	0.9992	1
Trypanosoma brucei	unspecified product	0.0022	0.0565	1
Echinococcus granulosus	dro:myosuppressin receptor	0.0138	0.9992	1
Brugia malayi	G protein-coupled receptor F59B2.13	0.0138	0.9992	0.9992
Brugia malayi	Serotonin receptor	0.0138	0.9992	0.9992
Loa Loa (eye worm)	GTP-binding regulatory protein Gs alpha-S chain	0.0046	0.2462	0.2442
Echinococcus granulosus	G protein coupled receptor 139	0.0138	0.9992	1
Echinococcus granulosus	hypothetical protein	0.0138	0.9992	1
Schistosoma mansoni	opsin-like receptor	0.0138	0.9992	1
Loa Loa (eye worm)	hypothetical protein	0.0138	0.9992	0.9992
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0138	0.9992	1
Echinococcus granulosus	7tm_1 domain containing protein	0.0138	0.9992	1
Brugia malayi	Dopamine receptor protein 1, putative (partial)	0.0138	0.9992	0.9992
Brugia malayi	Melatonin receptor type 1A	0.0138	0.9992	0.9992
Trypanosoma brucei	DNA polymerase kappa, putative	0.0022	0.0565	1
Loa Loa (eye worm)	melatonin receptor type 1A	0.0138	0.9992	0.9992
Leishmania major	DNA polymerase eta, putative	0.0022	0.0565	0.5
Loa Loa (eye worm)	G-protein-linked acetylcholine receptor protein 2	0.0138	0.9992	0.9992
Loa Loa (eye worm)	gonadotropin-releasing hormone receptor 2	0.0138	0.9992	0.9992
Brugia malayi	ORL1-like opioid receptor	0.0138	0.9992	0.9992
Schistosoma mansoni	peptide (allatostatin)-like receptor	0.0138	0.9992	1
Echinococcus multilocularis	sex peptide receptor	0.0138	0.9992	1
Echinococcus multilocularis	g protein coupled receptor	0.0138	0.9992	1
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0046	0.2462	0.2444
Loa Loa (eye worm)	hypothetical protein	0.0138	0.9992	0.9992
Schistosoma mansoni	rab geranylgeranyl transferase alpha subunit	0.0022	0.0565	0.0539
Onchocerca volvulus		0.0138	0.9992	0.5
Schistosoma mansoni	neuropeptide f receptor 76f	0.0138	0.9992	1
Echinococcus granulosus	rhodopsin orphan GPCR	0.0138	0.9992	1
Brugia malayi	Serotonin receptor	0.0138	0.9992	0.9992
Echinococcus granulosus	sex peptide receptor	0.0138	0.9992	1
Schistosoma mansoni	thyrotropin-releasing hormone receptor	0.0138	0.9992	1
Echinococcus granulosus	growth hormone secretagogue receptor type 1	0.0138	0.9992	1
Echinococcus granulosus	g-protein coupled receptor	0.0138	0.9992	1
Trypanosoma brucei	DNA polymerase IV, putative	0.0022	0.0565	1
Echinococcus granulosus	neuropeptide receptor	0.0138	0.9992	1
Echinococcus multilocularis	alpha 1A adrenergic receptor	0.0138	0.9992	1
Brugia malayi	putative neuropeptide receptor	0.0138	0.9992	0.9992
Brugia malayi	GnHR receptor homolog	0.0138	0.9992	0.9992
Onchocerca volvulus		0.0138	0.9992	0.5
Schistosoma mansoni	terminal deoxycytidyl transferase	0.0022	0.0565	0.0539
Loa Loa (eye worm)	hypothetical protein	0.0138	0.9992	0.9992
Trypanosoma cruzi	DNA polymerase kappa, putative	0.0022	0.0565	0.5
Loa Loa (eye worm)	hypothetical protein	0.0138	0.9992	0.9992
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0046	0.2462	0.2444
Schistosoma mansoni	hypothetical protein	0.0034	0.1515	0.1493
Brugia malayi	Unidentified vitellogenin-linked transcript protein 6, putative	0.0138	0.9992	0.9992
Schistosoma mansoni	adenoreceptor	0.0138	0.9992	1
Schistosoma mansoni	amine GPCR	0.0138	0.9992	1
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0138	0.9992	1
Brugia malayi	G-protein coupled receptor	0.0138	0.9992	0.9992
Echinococcus multilocularis	terminal deoxycytidyl transferase rev1	0.0022	0.0565	0.0539
Loa Loa (eye worm)	hypothetical protein	0.0138	0.9992	0.9992
Brugia malayi	Tachykinin-like peptides receptor 99D	0.0138	0.9992	0.9992
Echinococcus multilocularis	biogenic amine (5HT) receptor	0.0138	0.9992	1
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0138	0.9992	1
Trypanosoma brucei	DNA polymerase kappa, putative	0.0022	0.0565	1
Mycobacterium tuberculosis	Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed))	0.0022	0.0565	0.5
Loa Loa (eye worm)	hypothetical protein	0.0138	0.9992	0.9992
Leishmania major	DNA polymerase kappa, putative	0.0022	0.0565	0.5
Schistosoma mansoni	hypothetical protein	0.0138	0.9992	1
Echinococcus multilocularis	thyrotropin releasing hormone receptor	0.0138	0.9992	1
Echinococcus granulosus	rhodopsin orphan GPCR	0.0138	0.9992	1
Brugia malayi	Corticotropin releasing factor receptor 2 precursor, putative	0.005	0.2796	0.2777
Loa Loa (eye worm)	hypothetical protein	0.0138	0.9992	0.9992
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0138	0.9992	1
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0138	0.9992	1
Trypanosoma cruzi	DNA polymerase kappa, putative	0.0022	0.0565	0.5
Echinococcus granulosus	rhodopsin orphan GPCR	0.0138	0.9992	1
Trypanosoma brucei	DNA polymerase kappa, putative	0.0022	0.0565	1
Trypanosoma brucei	DNA polymerase kappa, putative	0.0022	0.0565	1
Echinococcus multilocularis	neuropeptide s receptor	0.0138	0.9992	1
Schistosoma mansoni	ancient conserved domain protein 2 (cyclin m2)	0.0138	0.9992	1
Echinococcus multilocularis	neuropeptide receptor A26	0.0138	0.9992	1
Trypanosoma brucei	DNA polymerase IV, putative	0.0022	0.0565	1
Loa Loa (eye worm)	hypothetical protein	0.0138	0.9992	0.9992
Loa Loa (eye worm)	hypothetical protein	0.0138	0.9992	0.9992
Schistosoma mansoni	alpha-1 adrenergic receptor	0.0138	0.9992	1
Trypanosoma brucei	DNA polymerase IV, putative	0.0022	0.0565	1
Echinococcus granulosus	fmrfamide receptor	0.0138	0.9992	1
Trypanosoma brucei	DNA polymerase kappa, putative	0.0022	0.0565	1
Trypanosoma brucei	DNA polymerase kappa, putative	0.0022	0.0565	1
Echinococcus granulosus	neuropeptide s receptor	0.0138	0.9992	1
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0138	0.9992	1
Echinococcus granulosus	g protein coupled receptor	0.0138	0.9992	1
Loa Loa (eye worm)	hypothetical protein	0.0138	0.9992	0.9992
Echinococcus granulosus	tm gpcr rhodopsin	0.0138	0.9992	1
Schistosoma mansoni	opsin-like receptor	0.0138	0.9992	1
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0138	0.9992	1
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0138	0.9992	1
Onchocerca volvulus		0.0138	0.9992	0.5
Echinococcus granulosus	alpha 1A adrenergic receptor	0.0138	0.9992	1
Loa Loa (eye worm)	neuropeptide F receptor	0.0138	0.9992	0.9992
Echinococcus granulosus	rhodopsin orphan GPCR	0.0138	0.9992	1
Echinococcus granulosus	biogenic amine 5HT receptor	0.0138	0.9992	1
Echinococcus granulosus	dna polymerase eta	0.0022	0.0565	0.0539
Schistosoma mansoni	opsin-like receptor	0.0138	0.9992	1
Schistosoma mansoni	tar DNA-binding protein	0.0063	0.3893	0.3879
Trypanosoma brucei	DNA polymerase eta, putative	0.0022	0.0565	1
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0138	0.9992	1
Loa Loa (eye worm)	hypothetical protein	0.0138	0.9992	0.9992
Loa Loa (eye worm)	G-protein coupled receptor	0.0138	0.9992	0.9992
Schistosoma mansoni	hypothetical protein	0.0138	0.9992	1
Brugia malayi	G-protein-linked acetylcholine receptor protein 2, putative	0.0138	0.9992	0.9992
Trypanosoma brucei	DNA polymerase kappa, putative	0.0022	0.0565	1
Echinococcus granulosus	tar DNA binding protein	0.0063	0.3893	0.3879
Onchocerca volvulus	Neuropeptide F receptor homolog	0.0138	0.9992	0.5
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0138	0.9992	1
Brugia malayi	sulfakinin receptor protein	0.0138	0.9992	0.9992
Loa Loa (eye worm)	hypothetical protein	0.0138	0.9992	0.9992
Echinococcus multilocularis	dna polymerase eta	0.0022	0.0565	0.0539
Echinococcus granulosus	7TM GPCR rhodopsin	0.0138	0.9992	1
Echinococcus multilocularis	7TM GPCR, rhodopsin	0.0138	0.9992	1
Loa Loa (eye worm)	hypothetical protein	0.0138	0.9992	0.9992
Loa Loa (eye worm)	hypothetical protein	0.0138	0.9992	0.9992
Onchocerca volvulus		0.0138	0.9992	0.5
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0138	0.9992	1
Echinococcus granulosus	G protein coupled 5 hydroxytryptamine receptor	0.0138	0.9992	1
Brugia malayi	Calcitonin receptor-like protein seb-1	0.005	0.2796	0.2777
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0138	0.9992	1
Trypanosoma cruzi	DNA polymerase eta, putative	0.0022	0.0565	0.5
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0138	0.9992	1
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0046	0.2462	0.2444
Brugia malayi	hypothetical protein	0.0138	0.9992	0.9992
Echinococcus multilocularis	orexin receptor type 2	0.0138	0.9992	1
Brugia malayi	ImpB/MucB/SamB family protein	0.0022	0.0565	0.0539
Loa Loa (eye worm)	hypothetical protein	0.0138	0.9992	0.9992
Loa Loa (eye worm)	hypothetical protein	0.0138	0.9992	0.9992
Trypanosoma brucei	DNA polymerase kappa, putative	0.0022	0.0565	1
Echinococcus granulosus	neuropeptide FF receptor 2	0.0138	0.9992	1
Echinococcus multilocularis	serotonin receptor	0.0138	0.9992	1
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0138	0.9992	1
Loa Loa (eye worm)	hypothetical protein	0.0138	0.9992	0.9992
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0138	0.9992	1
Loa Loa (eye worm)	ImpB/MucB/SamB family protein	0.0022	0.0565	0.0539
Brugia malayi	Dopamine receptor protein 2	0.0138	0.9992	0.9992
Loa Loa (eye worm)	hypothetical protein	0.0138	0.9992	0.9992
Schistosoma mansoni	amine GPCR	0.0138	0.9992	1
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0138	0.9992	1
Brugia malayi	hypothetical protein	0.0138	0.9992	0.9992
Loa Loa (eye worm)	RNA binding protein	0.0063	0.3893	0.3876
Schistosoma mansoni	peptide (allatostatin/somatostatin)-like receptor	0.0138	0.9992	1
Schistosoma mansoni	neuropeptide receptor	0.0138	0.9992	1
Trypanosoma brucei	DNA polymerase kappa, putative	0.0022	0.0565	1
Schistosoma mansoni	tar DNA-binding protein	0.0063	0.3893	0.3879
Schistosoma mansoni	neuropeptide F-like receptor	0.0138	0.9992	1
Echinococcus multilocularis	neuropeptide receptor	0.0138	0.9992	1
Echinococcus multilocularis	g protein coupled receptor	0.0138	0.9992	1
Echinococcus multilocularis	tar DNA binding protein	0.0063	0.3893	0.3879
Echinococcus granulosus	biogenic amine 5HT receptor	0.0138	0.9992	1
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0138	0.9992	1
Brugia malayi	RNA binding protein	0.0063	0.3893	0.3876
Trypanosoma cruzi	DNA polymerase kappa, putative	0.0022	0.0565	0.5
Loa Loa (eye worm)	hypothetical protein	0.0138	0.9992	0.9992
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0138	0.9992	1
Schistosoma mansoni	amine GPCR	0.0138	0.9992	1
Loa Loa (eye worm)	MH2 domain-containing protein	0.0138	1	1
Schistosoma mansoni	tar DNA-binding protein	0.0063	0.3893	0.3879
Echinococcus multilocularis	neuropeptide Y receptor	0.0138	0.9992	1
Loa Loa (eye worm)	hypothetical protein	0.0138	0.9992	0.9992
Schistosoma mansoni	neuropeptide receptor	0.0138	0.9992	1
Brugia malayi	latrophilin 2 splice variant baaae	0.0034	0.1515	0.1492
Echinococcus multilocularis	neuropeptides capa receptor	0.0138	0.9992	1
Brugia malayi	hypothetical protein	0.0138	0.9992	0.9992
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0046	0.2462	0.2444
Onchocerca volvulus		0.0138	0.9992	0.5
Schistosoma mansoni	tar DNA-binding protein	0.0063	0.3893	0.3879
Loa Loa (eye worm)	hypothetical protein	0.0138	0.9992	0.9992
Schistosoma mansoni	myosin xvIII	0.0138	0.9992	1
Onchocerca volvulus		0.0138	0.9992	0.5
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0046	0.2462	0.2444
Onchocerca volvulus		0.0138	0.9992	0.5
Brugia malayi	hypothetical protein	0.0138	0.9992	0.9992
Echinococcus granulosus	g protein coupled receptor	0.0138	0.9992	1
Schistosoma mansoni	muscarinic acetylcholine (GAR) receptor	0.0138	0.9992	1
Echinococcus granulosus	rhodopsin orphan GPCR	0.0138	0.9992	1
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0046	0.2462	0.2444
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0138	0.9992	1
Mycobacterium tuberculosis	Conserved hypothetical protein	0.0022	0.0565	0.5
Echinococcus granulosus	serotonin receptor	0.0138	0.9992	1
Schistosoma mansoni	histamine-responsive GPCR (AAF21638)	0.0138	0.9992	1
Brugia malayi	hypothetical protein	0.0138	0.9992	0.9992
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0565	0.0539
Loa Loa (eye worm)	hypothetical protein	0.0138	0.9992	0.9992
Echinococcus granulosus	neuropeptide receptor A26	0.0138	0.9992	1
Brugia malayi	RE15519p	0.0138	0.9992	0.9992
Mycobacterium ulcerans	DNA polymerase IV	0.0022	0.0565	0.5
Loa Loa (eye worm)	hypothetical protein	0.0138	0.9992	0.9992
Echinococcus granulosus	thyrotropin releasing hormone receptor	0.0138	0.9992	1
Schistosoma mansoni	biogenic amine receptor	0.0138	0.9992	1
Loa Loa (eye worm)	hypothetical protein	0.0138	0.9992	0.9992

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL3558992

Bibliographic References

No literature references available for this target.

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Detailed information for compound 1937070