Detailed information for compound 1937865

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 313.394 | Formula: C18H23N3O2
  • H donors: 0 H acceptors: 2 LogP: 1.33 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: COCCN1CCCCC21CC(=O)N(C2)c1cccc(c1)C#N
  • InChi: 1S/C18H23N3O2/c1-23-10-9-20-8-3-2-7-18(20)12-17(22)21(14-18)16-6-4-5-15(11-16)13-19/h4-6,11H,2-3,7-10,12,14H2,1H3
  • InChiKey: FFDOLUJJLJAUJQ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0048 1 1
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0048 1 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0048 1 1
Brugia malayi steroid hormone receptor 0.0032 0.4773 0.4773
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0048 1 1
Onchocerca volvulus 0.0048 1 1
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0048 1 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0032 0.4773 0.4773
Echinococcus multilocularis neuropeptides capa receptor 0.0048 1 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0048 1 1
Schistosoma mansoni hypothetical protein 0.0048 1 1
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0048 1 1
Schistosoma mansoni nuclear hormone receptor 0.0032 0.4773 0.4773
Echinococcus multilocularis neuropeptide Y receptor 0.0048 1 1
Echinococcus granulosus tm gpcr rhodopsin 0.0048 1 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0048 1 1
Loa Loa (eye worm) hypothetical protein 0.0048 1 1
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0048 1 1
Schistosoma mansoni amine GPCR 0.0048 1 1
Echinococcus multilocularis neuropeptide FF receptor 2 0.0048 1 1
Onchocerca volvulus 0.0048 1 1
Echinococcus granulosus alpha 1A adrenergic receptor 0.0048 1 1
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0048 1 1
Echinococcus granulosus neuropeptide FF receptor 2 0.0048 1 1
Echinococcus granulosus somatostatin receptor 0.0048 1 1
Loa Loa (eye worm) hypothetical protein 0.0048 1 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0032 0.4773 0.4773
Brugia malayi nuclear receptor NHR-88 0.0032 0.4773 0.4773
Brugia malayi Dopamine receptor 0.0048 1 1
Loa Loa (eye worm) hypothetical protein 0.0032 0.4773 0.4773
Loa Loa (eye worm) hypothetical protein 0.0048 1 1
Onchocerca volvulus 0.0048 1 1
Schistosoma mansoni neuropeptide F-like receptor 0.0048 1 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0048 1 1
Loa Loa (eye worm) steroid hormone receptor 0.0032 0.4773 0.4773
Brugia malayi hypothetical protein 0.0048 1 1
Echinococcus multilocularis neuropeptide Y receptor 0.0048 1 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0032 0.4773 0.4773
Brugia malayi hypothetical protein 0.0048 1 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0032 0.4773 0.4773
Echinococcus granulosus neuropeptide receptor 0.0048 1 1
Loa Loa (eye worm) TYRA-2 protein 0.0048 1 1
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0048 1 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0032 0.4773 0.4773
Echinococcus granulosus g protein coupled receptor 0.0048 1 1
Schistosoma mansoni growth hormone secretagogue receptor 0.0048 1 1
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0032 0.4773 0.4773
Brugia malayi photoreceptor-specific nuclear receptor 0.0032 0.4773 0.4773
Echinococcus multilocularis g protein coupled receptor 0.0048 1 1
Brugia malayi G protein-coupled receptor 0.0048 1 1
Loa Loa (eye worm) hypothetical protein 0.0048 1 1
Loa Loa (eye worm) hypothetical protein 0.0032 0.4773 0.4773
Loa Loa (eye worm) neuropeptide F receptor 0.0048 1 1
Loa Loa (eye worm) hypothetical protein 0.0048 1 1
Onchocerca volvulus 0.0048 1 1
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0032 0.4773 0.4773
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0032 0.4773 0.4773
Loa Loa (eye worm) hypothetical protein 0.0048 1 1
Echinococcus granulosus neuropeptide receptor A26 0.0048 1 1
Brugia malayi hypothetical protein 0.0048 1 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0048 1 1
Loa Loa (eye worm) G-protein coupled receptor 0.0048 1 1
Schistosoma mansoni amine GPCR 0.0048 1 1
Loa Loa (eye worm) hypothetical protein 0.0048 1 1
Echinococcus granulosus G protein coupled receptor 139 0.0048 1 1
Echinococcus granulosus allatostatin A receptor 0.0048 1 1
Onchocerca volvulus Neuropeptide F receptor homolog 0.0048 1 1
Echinococcus multilocularis dro:myosuppressin receptor 0.0048 1 1
Brugia malayi hypothetical protein 0.0048 1 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0032 0.4773 0.4773
Echinococcus multilocularis orexin receptor type 2 0.0048 1 1
Echinococcus granulosus tm gpcr rhodopsin 0.0048 1 1
Loa Loa (eye worm) hypothetical protein 0.0048 1 1
Brugia malayi Steroid receptor seven-up type 2 0.0032 0.4773 0.4773
Echinococcus granulosus neuropeptide s receptor 0.0048 1 1
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0048 1 1
Brugia malayi AKH receptor 0.0048 1 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0048 1 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0032 0.4773 0.4773
Schistosoma mansoni steroid hormone receptor ad4bp 0.0032 0.4773 0.4773
Echinococcus multilocularis fmrfamide receptor 0.0048 1 1
Echinococcus granulosus 7TM GPCR rhodopsin 0.0048 1 1
Echinococcus granulosus biogenic amine 5HT receptor 0.0048 1 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0048 1 1
Echinococcus granulosus g protein coupled receptor 0.0048 1 1
Loa Loa (eye worm) hypothetical protein 0.0048 1 1
Loa Loa (eye worm) hypothetical protein 0.0048 1 1
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0032 0.4773 0.4773
Schistosoma mansoni hypothetical protein 0.0048 1 1
Onchocerca volvulus 0.0048 1 1
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0032 0.4773 0.4773
Echinococcus multilocularis rhodopsin orphan GPCR 0.0048 1 1
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0048 1 1
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0032 0.4773 0.4773
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0032 0.4773 0.4773
Brugia malayi G protein-coupled receptor F59B2.13 0.0048 1 1
Schistosoma mansoni biogenic amine receptor 0.0048 1 1
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0048 1 1
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0032 0.4773 0.4773
Echinococcus granulosus rhodopsin orphan GPCR 0.0048 1 1
Brugia malayi larval opioid receptor 0.0048 1 1
Loa Loa (eye worm) hypothetical protein 0.0048 1 1
Echinococcus multilocularis G protein coupled receptor 139 0.0048 1 1
Schistosoma mansoni amine GPCR 0.0048 1 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0048 1 1
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0032 0.4773 0.4773
Schistosoma mansoni adenoreceptor 0.0048 1 1
Echinococcus granulosus neuropeptides capa receptor 0.0048 1 1
Brugia malayi sulfakinin receptor protein 0.0048 1 1
Loa Loa (eye worm) hypothetical protein 0.0048 1 1
Brugia malayi Serotonin receptor 0.0048 1 1
Loa Loa (eye worm) hypothetical protein 0.0048 1 1
Loa Loa (eye worm) hypothetical protein 0.0048 1 1
Brugia malayi Tachykinin-like peptides receptor 99D 0.0048 1 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0048 1 1
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0048 1 1
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0032 0.4773 0.4773
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0048 1 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0032 0.4773 0.4773
Echinococcus multilocularis FTZ F1 alpha 0.0032 0.4773 0.4773
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0048 1 1
Loa Loa (eye worm) hypothetical protein 0.0048 1 1
Loa Loa (eye worm) hypothetical protein 0.0048 1 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0048 1 1
Brugia malayi ecdysteroid receptor 0.0032 0.4773 0.4773
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0048 1 1
Echinococcus granulosus neuropeptide Y receptor 0.0048 1 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0048 1 1
Onchocerca volvulus 0.0048 1 1
Schistosoma mansoni opsin-like receptor 0.0048 1 1
Onchocerca volvulus 0.0048 1 1
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0048 1 1
Loa Loa (eye worm) hypothetical protein 0.0048 1 1
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0048 1 1
Schistosoma mansoni neuropeptide receptor 0.0048 1 1
Echinococcus granulosus peptide allatostatin:somatostatin 0.0048 1 1
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0048 1 1
Schistosoma mansoni neuropeptide receptor 0.0048 1 1
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0032 0.4773 0.4773
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0048 1 1
Echinococcus granulosus ecdysone induced protein 78C 0.0032 0.4773 0.4773
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0032 0.4773 0.4773
Echinococcus granulosus neuropeptides capa receptor 0.0048 1 1
Loa Loa (eye worm) neuropeptide F receptor 0.0048 1 1
Brugia malayi G-protein coupled receptor 0.0048 1 1
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0048 1 1
Echinococcus multilocularis somatostatin receptor 0.0048 1 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0048 1 1
Schistosoma mansoni neuropeptide f receptor 76f 0.0048 1 1
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0048 1 1
Schistosoma mansoni neuropeptide F-like receptor 0.0048 1 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0032 0.4773 0.4773
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0048 1 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0032 0.4773 0.4773
Loa Loa (eye worm) hypothetical protein 0.0032 0.4773 0.4773
Onchocerca volvulus 0.0048 1 1
Schistosoma mansoni opsin-like receptor 0.0048 1 1
Loa Loa (eye worm) hypothetical protein 0.0048 1 1
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0048 1 1
Echinococcus multilocularis neuropeptide receptor 0.0048 1 1
Echinococcus granulosus tm gpcr rhodopsin 0.0048 1 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0048 1 1
Brugia malayi hypothetical protein 0.0048 1 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0048 1 1
Onchocerca volvulus 0.0048 1 1
Echinococcus multilocularis g-protein coupled receptor 0.0048 1 1
Echinococcus granulosus FTZ F1 alpha 0.0032 0.4773 0.4773
Onchocerca volvulus 0.0048 1 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0048 1 1
Echinococcus granulosus neuropeptide receptor 0.0048 1 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0048 1 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0032 0.4773 0.4773
Loa Loa (eye worm) hypothetical protein 0.0048 1 1
Schistosoma mansoni histamine h1 receptor 0.0048 1 1
Echinococcus multilocularis serotonin receptor 0.0048 1 1
Schistosoma mansoni coup transcription factor 0.0032 0.4773 0.4773
Echinococcus granulosus fmrfamide receptor 0.0048 1 1
Loa Loa (eye worm) hypothetical protein 0.0032 0.4773 0.4773
Schistosoma mansoni thyroid hormone receptor 0.0032 0.4773 0.4773
Echinococcus granulosus dro:myosuppressin receptor 0.0048 1 1
Loa Loa (eye worm) hypothetical protein 0.0048 1 1
Loa Loa (eye worm) hypothetical protein 0.0048 1 1
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0032 0.4773 0.4773
Loa Loa (eye worm) hypothetical protein 0.0048 1 1
Brugia malayi nuclear hormone receptor 0.0032 0.4773 0.4773
Schistosoma mansoni neuropeptide receptor 0.0048 1 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0048 1 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0048 1 1
Brugia malayi Nuclear hormone receptor-like 1 0.0032 0.4773 0.4773
Brugia malayi neuropeptide F receptor 0.0048 1 1
Schistosoma mansoni biogenic amine (5HT) receptor 0.0048 1 1
Echinococcus granulosus orexin receptor type 2 0.0048 1 1
Schistosoma mansoni opsin-like receptor 0.0048 1 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0048 1 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0048 1 1
Brugia malayi RE15519p 0.0048 1 1
Loa Loa (eye worm) hypothetical protein 0.0048 1 1
Onchocerca volvulus 0.0048 1 1
Loa Loa (eye worm) hypothetical protein 0.0048 1 1
Brugia malayi hypothetical protein 0.0048 1 1
Loa Loa (eye worm) hypothetical protein 0.0048 1 1
Loa Loa (eye worm) hypothetical protein 0.0048 1 1
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0032 0.4773 0.4773
Echinococcus granulosus g protein coupled receptor 0.0048 1 1
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0048 1 1
Echinococcus granulosus neuropeptide Y receptor 0.0048 1 1
Loa Loa (eye worm) hypothetical protein 0.0032 0.4773 0.4773
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0048 1 1
Brugia malayi Dopamine receptor protein 2 0.0048 1 1
Loa Loa (eye worm) hypothetical protein 0.0048 1 1
Brugia malayi follicle stimulating hormone receptor 0.0048 1 1
Onchocerca volvulus 0.0048 1 1
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0048 1 1
Loa Loa (eye worm) G-protein coupled receptor 0.0048 1 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0048 1 1
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0032 0.4773 0.4773
Echinococcus multilocularis neuropeptide receptor 0.0048 1 1
Schistosoma mansoni neuropeptide receptor 0.0048 1 1
Brugia malayi hypothetical protein 0.0048 1 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0032 0.4773 0.4773
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0048 1 1
Loa Loa (eye worm) hypothetical protein 0.0048 1 1
Onchocerca volvulus 0.0048 1 1
Echinococcus multilocularis fmrfamide receptor 0.0048 1 1
Loa Loa (eye worm) hypothetical protein 0.0048 1 1
Echinococcus multilocularis neuropeptide s receptor 0.0048 1 1
Schistosoma mansoni thyroid hormone receptor 0.0032 0.4773 0.4773
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0048 1 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0048 1 1
Echinococcus multilocularis g protein coupled receptor 0.0048 1 1
Schistosoma mansoni biogenic amine (5HT) receptor 0.0048 1 1
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0032 0.4773 0.4773
Brugia malayi neuropeptide F receptor 0.0048 1 1
Echinococcus multilocularis ecdysone induced protein 78C 0.0032 0.4773 0.4773
Onchocerca volvulus 0.0048 1 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0032 0.4773 0.4773
Echinococcus multilocularis rhodopsin orphan GPCR 0.0048 1 1
Loa Loa (eye worm) hypothetical protein 0.0048 1 1
Echinococcus granulosus serotonin receptor 0.0048 1 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0032 0.4773 0.4773
Brugia malayi GnHR receptor homolog 0.0048 1 1
Loa Loa (eye worm) hypothetical protein 0.0048 1 1
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0048 1 1
Echinococcus multilocularis allatostatin A receptor 0.0048 1 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0048 1 1
Brugia malayi Melatonin receptor type 1A 0.0048 1 1
Brugia malayi putative neuropeptide receptor 0.0048 1 1
Echinococcus multilocularis thyroid hormone receptor alpha 0.0032 0.4773 0.4773
Loa Loa (eye worm) hypothetical protein 0.0048 1 1
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0032 0.4773 0.4773
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0032 0.4773 0.4773
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0048 1 1
Schistosoma mansoni myosin xvIII 0.0048 1 1
Loa Loa (eye worm) hypothetical protein 0.0048 1 1
Echinococcus multilocularis serotonin receptor 0.0048 1 1
Schistosoma mansoni retinoic acid receptor RXR 0.0032 0.4773 0.4773
Schistosoma mansoni biogenic amine receptor 0.0048 1 1
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0048 1 1
Echinococcus granulosus tachykinin peptides receptor 99D 0.0048 1 1
Loa Loa (eye worm) hypothetical protein 0.0048 1 1
Schistosoma mansoni RAR-like nuclear receptor 0.0032 0.4773 0.4773
Echinococcus granulosus hypothetical protein 0.0048 1 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0048 1 1
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0048 1 1
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0032 0.4773 0.4773
Loa Loa (eye worm) hypothetical protein 0.0048 1 1
Loa Loa (eye worm) hypothetical protein 0.0048 1 1
Loa Loa (eye worm) melatonin receptor type 1A 0.0048 1 1
Echinococcus granulosus sex peptide receptor 0.0048 1 1
Echinococcus multilocularis g protein coupled receptor 0.0048 1 1
Echinococcus granulosus 7tm_1 domain containing protein 0.0048 1 1
Loa Loa (eye worm) hypothetical protein 0.0048 1 1
Loa Loa (eye worm) hypothetical protein 0.0032 0.4773 0.4773
Loa Loa (eye worm) hypothetical protein 0.0048 1 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0048 1 1
Loa Loa (eye worm) hypothetical protein 0.0048 1 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0032 0.4773 0.4773
Echinococcus multilocularis sex peptide receptor 0.0048 1 1
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0032 0.4773 0.4773
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0048 1 1
Loa Loa (eye worm) hypothetical protein 0.0048 1 1
Schistosoma mansoni amine GPCR 0.0048 1 1
Schistosoma mansoni hypothetical protein 0.0048 1 1
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0032 0.4773 0.4773
Schistosoma mansoni alpha-1 adrenergic receptor 0.0048 1 1
Brugia malayi hypothetical protein 0.0048 1 1
Schistosoma mansoni hypothetical protein 0.0048 1 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0048 1 1
Schistosoma mansoni amine GPCR 0.0048 1 1
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0048 1 1
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0048 1 1
Schistosoma mansoni biogenic amine receptor 0.0048 1 1
Onchocerca volvulus 0.0048 1 1
Brugia malayi G-protein coupled receptor 0.0048 1 1
Echinococcus multilocularis neuropeptide receptor A26 0.0048 1 1
Brugia malayi putative neuropeptide receptor NPR1 0.0048 1 1
Loa Loa (eye worm) hypothetical protein 0.0048 1 1
Loa Loa (eye worm) hypothetical protein 0.0048 1 1
Echinococcus granulosus g-protein coupled receptor 0.0048 1 1
Loa Loa (eye worm) hypothetical protein 0.0048 1 1
Brugia malayi Serotonin receptor 0.0048 1 1
Brugia malayi ORL1-like opioid receptor 0.0048 1 1
Echinococcus multilocularis neuropeptides capa receptor 0.0048 1 1
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0048 1 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0048 1 1
Loa Loa (eye worm) hypothetical protein 0.0048 1 1
Brugia malayi Dopamine receptor protein 1 0.0048 1 1
Echinococcus granulosus biogenic amine 5HT receptor 0.0048 1 1
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0032 0.4773 0.4773
Loa Loa (eye worm) hypothetical protein 0.0048 1 1
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0032 0.4773 0.4773
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0048 1 1
Loa Loa (eye worm) hypothetical protein 0.0032 0.4773 0.4773
Onchocerca volvulus 0.0048 1 1
Echinococcus multilocularis G-protein coupled receptor, putative 0.0048 1 1
Onchocerca volvulus 0.0048 1 1
Loa Loa (eye worm) hypothetical protein 0.0032 0.4773 0.4773
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0032 0.4773 0.4773
Brugia malayi hypothetical protein 0.0048 1 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0048 1 1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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