Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0018 | 0.333 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.667 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0035 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0027 | 0.667 | 0.6246 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0035 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0014 | 0.1831 | 0.0792 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0035 | 1 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0035 | 1 | 1 |
Schistosoma mansoni | DNA polymerase eta | 0.0012 | 0.1129 | 0.5 |
Toxoplasma gondii | BRCA1 C Terminus (BRCT) domain-containing protein | 0.001 | 0 | 0.5 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0018 | 0.333 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0035 | 1 | 1 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0035 | 1 | 0.5 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0035 | 1 | 0.5 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0012 | 0.1129 | 0.5 |
Echinococcus multilocularis | dna polymerase kappa | 0.0035 | 1 | 1 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0012 | 0.1129 | 0.5 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0035 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0035 | 1 | 1 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0012 | 0.1129 | 0.5 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.003 | 0.7799 | 0.7519 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0035 | 1 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0035 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0035 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0014 | 0.1831 | 0.0792 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0035 | 1 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0035 | 1 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0035 | 1 | 1 |
Trypanosoma brucei | unspecified product | 0.003 | 0.7799 | 0.7519 |
Giardia lamblia | DINP protein human, muc B family | 0.0018 | 0.333 | 0.5 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0035 | 1 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0018 | 0.333 | 0.2481 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0027 | 0.667 | 0.6246 |
Brugia malayi | polk-prov protein | 0.0027 | 0.667 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0014 | 0.1831 | 0.0792 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0035 | 1 | 1 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0035 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0035 | 1 | 1 |
Leishmania major | DNA polymerase kappa, putative | 0.0018 | 0.333 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.