Detailed information for compound 1943823

Basic information

Technical information
  • TDR Targets ID: 1943823
  • Name: 11R-0257
  • MW: 373.213 | Formula: C14H5F6N5O
  • H donors: 0 H acceptors: 4 LogP: 3.69 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: FC(c1nc2n3cc(nc3ccc2c(c1)C(F)(F)F)c1nnco1)(F)F
  • InChi: 1S/C14H5F6N5O/c15-13(16,17)7-3-9(14(18,19)20)23-11-6(7)1-2-10-22-8(4-25(10)11)12-24-21-5-26-12/h1-5H
  • InChiKey: GRHYZVJEXKTJOS-UHFFFAOYSA-N  

Network

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Synonyms

  • Bionet1_000075
  • MixCom2_000289
  • ZINC04002526

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Loa Loa (eye worm) carboxylesterase 0.0071 0.1011 0.1588
Plasmodium falciparum tubulin epsilon chain, putative 0.0128 0.1977 0.5025
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0036 0.0433 0.1042
Echinococcus granulosus twik family of potassium channels 0.0019 0.0144 0.0144
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0016 0.0088 0.0088
Plasmodium falciparum ataxin-2 like protein, putative 0.0095 0.142 0.3588
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.002 0.0165 0.0165
Trypanosoma cruzi hypothetical protein, conserved 0.0062 0.0866 0.204
Plasmodium falciparum glutathione reductase 0.0016 0.0088 0.015
Mycobacterium tuberculosis Possible transmembrane cation transporter 0.0019 0.0144 0.0184
Loa Loa (eye worm) norepinephrine transporter 0.0058 0.0791 0.1241
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0177 0.2795 0.7137
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0144 0.0147
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0017 0.0104 0.0122
Leishmania major beta tubulin 0.0243 0.3904 1
Trichomonas vaginalis tubulin beta chain, putative 0.0176 0.277 0.7075
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.004
Loa Loa (eye worm) hypothetical protein 0.0145 0.2249 0.3532
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0036 0.0433 0.1042
Loa Loa (eye worm) RecQ helicase 0.0019 0.0139 0.0219
Trichomonas vaginalis tubulin epsilon chain, putative 0.0243 0.3904 1
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.002 0.0165 0.0165
Loa Loa (eye worm) hypothetical protein 0.0019 0.0144 0.0226
Onchocerca volvulus 0.0025 0.0245 0.0987
Entamoeba histolytica acetyltransferase, GNAT family 0.0061 0.0849 0.2114
Schistosoma mansoni rab6-interacting 0.0025 0.0245 0.0245
Echinococcus multilocularis tubulin alpha 3 chain 0.0176 0.277 0.277
Echinococcus multilocularis geminin 0.0483 0.7924 0.7924
Trypanosoma cruzi tubulin delta chain 0.0056 0.0759 0.1759
Echinococcus multilocularis voltage dependent calcium channel 0.009 0.133 0.133
Echinococcus multilocularis jumonji domain containing protein 0.0028 0.0291 0.0291
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0065 0.0916 0.0916
Loa Loa (eye worm) beta-lactamase 0.0062 0.0866 0.136
Echinococcus granulosus Tubulin alpha 1 chain 0.0176 0.277 0.277
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.002 0.0165 0.0165
Plasmodium falciparum alpha tubulin 1 0.0176 0.277 0.7072
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0062 0.0866 0.136
Schistosoma mansoni ubiquitin conjugating enzyme 13 0.0026 0.0264 0.0264
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0036 0.0433 0.1042
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.004
Schistosoma mansoni lipoxygenase 0.015 0.2337 0.2337
Toxoplasma gondii melibiase subfamily protein 0.0065 0.0916 0.2287
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0019 0.0144 0.0305
Entamoeba histolytica hypothetical protein 0.0034 0.0402 0.0962
Brugia malayi Flap endonuclease-1 0.0018 0.0124 0.0213
Echinococcus granulosus lysosomal alpha glucosidase 0.0106 0.16 0.16
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0026 0.0264 0.0461
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0073 0.105 0.18
Echinococcus granulosus tubulin alpha 3 chain 0.0176 0.277 0.277
Trichomonas vaginalis tubulin alpha chain, putative 0.0073 0.1042 0.2622
Trichomonas vaginalis tubulin beta chain, putative 0.0176 0.277 0.7075
Echinococcus multilocularis Two pore potassium channel protein sup 9 0.0019 0.0144 0.0144
Echinococcus granulosus tubulin gamma 1 chain 0.0128 0.1977 0.1977
Plasmodium falciparum potassium channel 0.0019 0.0144 0.0295
Plasmodium vivax hypothetical protein, conserved 0.0062 0.0866 0.2159
Loa Loa (eye worm) tubulin alpha chain 0.0176 0.277 0.435
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.004
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0036 0.0433 0.0905
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0019 0.0144 0.0305
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0177 0.2795 0.7137
Leishmania major gamma-tubulin 0.0128 0.1977 0.5025
Leishmania major beta tubulin 0.0243 0.3904 1
Trypanosoma brucei beta tubulin 0.0243 0.3904 1
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0065 0.0916 0.0916
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0018 0.0124 0.0245
Leishmania major beta tubulin 0.0243 0.3904 1
Giardia lamblia Fructose-bisphosphate aldolase 0.0177 0.2795 0.7093
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0017 0.0104 0.0043
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.002 0.0165 0.0217
Echinococcus granulosus Polycystic kidney disease protein 0.0025 0.0245 0.0245
Loa Loa (eye worm) hypothetical protein 0.0011 0.0009 0.0015
Trypanosoma cruzi tubulin delta chain 0.0056 0.0759 0.1759
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0017 0.0104 0.063
Loa Loa (eye worm) acetyltransferase 0.0226 0.3623 0.5689
Trichomonas vaginalis mercuric reductase, putative 0.0016 0.0088 0.0161
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0017 0.0104 0.0122
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0012 0.0025 0.0025
Giardia lamblia Delta tubulin 0.0056 0.0759 0.1759
Echinococcus granulosus voltage dependent calcium channel 0.0031 0.0349 0.0349
Trypanosoma brucei beta tubulin 0.0243 0.3904 1
Trypanosoma brucei calcium/potassium channel (CAKC), putative 0.0019 0.0144 0.0295
Mycobacterium tuberculosis Conserved protein 0.0062 0.0866 0.1303
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0013 0.0037 0.0021
Echinococcus multilocularis neutral alpha glucosidase AB 0.0023 0.0219 0.0219
Brugia malayi Calcitonin receptor-like protein seb-1 0.0064 0.0899 0.1542
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.002 0.0165 0.035
Echinococcus granulosus histone acetyltransferase KAT2B 0.0067 0.0942 0.0942
Giardia lamblia Beta tubulin 0.0243 0.3904 1
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0017 0.0104 0.063
Echinococcus granulosus neuroligin 0.0012 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.004
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0016 0.0088 0.0798
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0062 0.0866 0.1303
Echinococcus granulosus voltage dependent calcium channel 0.009 0.133 0.133
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 30. 0.0019 0.0144 0.0247
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0017 0.0104 0.0122
Schistosoma mansoni cytochrome P450 0.0017 0.0104 0.0104
Loa Loa (eye worm) hypothetical protein 0.0062 0.0866 0.136
Trichomonas vaginalis esterase, putative 0.0062 0.0866 0.2168
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.002 0.0165 0.0203
Trichomonas vaginalis set domain proteins, putative 0.0143 0.2232 0.5688
Trypanosoma brucei zeta tubulin 0.0056 0.0759 0.1883
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0047 0.0613 0.0613
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0176 0.277 0.7075
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0043 0.0552 0.0552
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0034 0.0402 0.0402
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.009 0.133 0.133
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0026 0.0264 0.0414
Schistosoma mansoni hypothetical protein 0.002 0.016 0.016
Trypanosoma brucei tubulin gamma chain 0.0128 0.1977 0.5025
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0021 0.0177 0.0235
Giardia lamblia Beta tubulin 0.0243 0.3904 1
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0016 0.0088 0.0798
Trypanosoma brucei glucosidase, putative 0.0023 0.0219 0.0488
Plasmodium vivax tubulin alpha chain, putative 0.0176 0.277 0.7072
Schistosoma mansoni tubulin subunit alpha 0.0176 0.277 0.277
Loa Loa (eye worm) hypothetical protein 0.0019 0.0144 0.0226
Echinococcus multilocularis potassium channel subfamily K 8 0.0019 0.0144 0.0144
Loa Loa (eye worm) hypothetical protein 0.009 0.133 0.2089
Echinococcus multilocularis lipoxygenase domain containing protein 0.0025 0.0245 0.0245
Loa Loa (eye worm) hypothetical protein 0.0019 0.0144 0.0226
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0017 0.0104 0.063
Trypanosoma brucei epsilon tubulin 0.0128 0.1977 0.5025
Echinococcus multilocularis lysosomal alpha glucosidase 0.0106 0.16 0.16
Loa Loa (eye worm) hypothetical protein 0.0025 0.0245 0.0384
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0106 0.16 0.2513
Echinococcus granulosus Tubulin beta 2C chain 0.0243 0.3904 0.3904
Mycobacterium tuberculosis Probable esterase LipL 0.0062 0.0866 0.1303
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0043 0.054 0.054
Loa Loa (eye worm) hypothetical protein 0.0016 0.0094 0.0148
Brugia malayi Cytochrome P450 family protein 0.0033 0.0374 0.0641
Echinococcus granulosus Two pore potassium channel protein sup 9 0.0019 0.0144 0.0144
Echinococcus multilocularis thioredoxin glutathione reductase 0.0045 0.0583 0.0583
Schistosoma mansoni twik family of potassium channels-related 0.0019 0.0144 0.0144
Brugia malayi Inositol-1 0.0023 0.0218 0.0374
Plasmodium vivax glutathione reductase, putative 0.0045 0.0583 0.143
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0017 0.0104 0.063
Leishmania major beta tubulin 0.0243 0.3904 1
Echinococcus granulosus tubulin alpha 1C chain 0.0176 0.277 0.277
Schistosoma mansoni polycystin 1-related 0.0025 0.0245 0.0245
Leishmania major alpha tubulin 0.0176 0.277 0.7072
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0226 0.3623 0.3623
Echinococcus granulosus cytochrome P450 2K1 0.0017 0.0104 0.0104
Brugia malayi Tubulin beta chain 0.0073 0.1042 0.1788
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0103 0.1555 0.2371
Echinococcus multilocularis tubulin alpha chain 0.0176 0.277 0.277
Mycobacterium tuberculosis Probable lipase LipD 0.0062 0.0866 0.1303
Echinococcus granulosus transcription factor Dp 1 0.0024 0.0232 0.0232
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0017 0.0104 0.0122
Brugia malayi Thioredoxin reductase 0.0045 0.0583 0.1001
Entamoeba histolytica tubulin family protein 0.0243 0.3904 1
Brugia malayi Intermediate filament tail domain containing protein 0.0024 0.0222 0.0381
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0023 0.0218 0.0342
Loa Loa (eye worm) hypothetical protein 0.0019 0.0144 0.0226
Trypanosoma cruzi calcium/potassium channel (CAKC), putative 0.0019 0.0144 0.0147
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0017 0.0104 0.063
Trichomonas vaginalis D-aminoacylase, putative 0.0062 0.0866 0.2168
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0067 0.0942 0.2363
Loa Loa (eye worm) hypothetical protein 0.0019 0.0144 0.0226
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0012 0.0029 0.0006
Schistosoma mansoni hypothetical protein 0.002 0.0165 0.0165
Schistosoma mansoni tubulin subunit alpha 0.0176 0.277 0.277
Onchocerca volvulus 0.0061 0.0852 0.3716
Schistosoma mansoni tubulin subunit beta 0.0243 0.3904 0.3904
Loa Loa (eye worm) thioredoxin reductase 0.0045 0.0583 0.0916
Echinococcus granulosus potassium channel subfamily K 8 0.0019 0.0144 0.0144
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0017 0.0104 0.0193
Onchocerca volvulus 0.0018 0.0128 0.0462
Echinococcus granulosus tubulin epsilon chain 0.0128 0.1977 0.1977
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0017 0.0104 0.063
Brugia malayi hypothetical protein 0.0145 0.2249 0.3858
Schistosoma mansoni hypothetical protein 0.039 0.6368 0.6368
Schistosoma mansoni hypothetical protein 0.0483 0.7924 0.7924
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0177 0.2795 0.714
Toxoplasma gondii alpha tubulin TUBA1 0.0176 0.277 0.7072
Loa Loa (eye worm) hypothetical protein 0.0019 0.0144 0.0226
Schistosoma mansoni blooms syndrome DNA helicase 0.0015 0.0073 0.0073
Schistosoma mansoni alpha glucosidase 0.0023 0.0219 0.0219
Plasmodium vivax hypothetical protein, conserved 0.002 0.016 0.0337
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0017 0.0104 0.063
Trypanosoma cruzi zeta tubulin, putative 0.0056 0.0759 0.1759
Echinococcus granulosus flap endonuclease 1 0.0018 0.0124 0.0124
Schistosoma mansoni sodium/chloride dependent transporter 0.0058 0.0791 0.0791
Echinococcus granulosus BC026374 protein S09 family 0.0012 0.0025 0.0025
Echinococcus granulosus beta LACTamase domain containing family member 0.0062 0.0866 0.0866
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0056 0.0759 1
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 5 0.0019 0.0144 0.0247
Loa Loa (eye worm) transcription factor SMAD2 0.0153 0.2397 0.3765
Brugia malayi hypothetical protein 0.0019 0.0144 0.0247
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.009 0.133 0.133
Giardia lamblia Alpha-tubulin 0.0176 0.277 0.7028
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0016 0.0088 0.0499
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0026 0.0264 0.0614
Trichomonas vaginalis tubulin beta chain, putative 0.0073 0.1042 0.2622
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0042 0.0528 0.0528
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0042 0.0528 0.0829
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0088 0.015
Loa Loa (eye worm) tubulin beta-2A chain 0.0243 0.3904 0.6131
Toxoplasma gondii beta-1 tubulin, putative 0.0243 0.3904 1
Entamoeba histolytica hypothetical protein 0.0034 0.0402 0.0962
Leishmania major hypothetical protein, conserved 0.0095 0.142 0.3588
Echinococcus multilocularis potassium channel subfamily K 8 0.0019 0.0144 0.0144
Loa Loa (eye worm) hypothetical protein 0.0019 0.0144 0.0226
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0243 0.3904 0.3904
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0023 0.0219 0.0488
Echinococcus granulosus histone acetyltransferase KAT2B 0.022 0.3517 0.3517
Trichomonas vaginalis maltase-glucoamylase, putative 0.0023 0.0219 0.0499
Toxoplasma gondii LsmAD domain-containing protein 0.0095 0.142 0.3588
Brugia malayi hypothetical protein 0.0034 0.0402 0.0689
Brugia malayi MH2 domain containing protein 0.0153 0.2397 0.4112
Loa Loa (eye worm) hypothetical protein 0.0019 0.0144 0.0226
Loa Loa (eye worm) hypothetical protein 0.0019 0.0144 0.0226
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0047 0.0613 0.1505
Trypanosoma cruzi PAB1-binding protein , putative 0.0095 0.142 0.349
Leishmania major potassium channel subunit-like protein 0.0019 0.0144 0.0295
Mycobacterium leprae Conserved hypothetical protein 0.0017 0.0104 0.0434
Plasmodium falciparum thioredoxin reductase 0.0045 0.0583 0.143
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 19. C. elegans unc-58 ortholog 0.0019 0.0144 0.0247
Schistosoma mansoni hypothetical protein 0.0019 0.0144 0.0144
Echinococcus multilocularis transcription factor Dp 1 0.0024 0.0232 0.0232
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0088 0.015
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0023 0.0218 0.0487
Trichomonas vaginalis penicillin-binding protein, putative 0.0062 0.0866 0.2168
Trichomonas vaginalis tubulin, putative 0.0243 0.3904 1
Entamoeba histolytica tubulin gamma chain 0.0128 0.1977 0.5025
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0023 0.0218 0.0487
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0017 0.0104 0.063
Loa Loa (eye worm) hypothetical protein 0.0019 0.0144 0.0226
Onchocerca volvulus 0.0073 0.1042 0.4573
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0017 0.0104 0.0122
Schistosoma mansoni survival motor neuron protein 0.0073 0.105 0.105
Loa Loa (eye worm) hypothetical protein 0.0071 0.1011 0.1588
Trypanosoma cruzi ion transport protein, putative 0.0019 0.0144 0.0147
Schistosoma mansoni tubulin subunit alpha 0.0176 0.277 0.277
Brugia malayi Pre-SET motif family protein 0.0126 0.194 0.3327
Echinococcus multilocularis bloom syndrome protein 0.0019 0.0139 0.0139
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.002 0.0165 0.0282
Echinococcus multilocularis tubulin alpha chain 0.0176 0.277 0.277
Echinococcus granulosus Tubulin beta 2C chain 0.0243 0.3904 0.3904
Schistosoma mansoni twik family of potassium channels-related 0.0019 0.0144 0.0144
Loa Loa (eye worm) PHD-finger family protein 0.002 0.016 0.0251
Schistosoma mansoni tubulin subunit beta 0.0243 0.3904 0.3904
Trichomonas vaginalis tubulin alpha chain, putative 0.0128 0.1977 0.503
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0126 0.194 0.3046
Plasmodium falciparum alpha tubulin 2 0.0176 0.277 0.7072
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0177 0.2795 0.714
Echinococcus multilocularis inositol monophosphatase 1 0.0023 0.0218 0.0218
Onchocerca volvulus 0.0073 0.105 0.4606
Trichomonas vaginalis tubulin alpha chain, putative 0.0073 0.1042 0.2622
Schistosoma mansoni calcium-activated potassium channel 0.0371 0.6049 0.6049
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0036 0.0433 0.0905
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0062 0.0866 0.0866
Schistosoma mansoni BC026374 protein (S09 family) 0.0012 0.0025 0.0025
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0011 0.0017 0.0017
Onchocerca volvulus 0.0145 0.2249 1
Echinococcus multilocularis peroxisome assembly protein 26 0.0176 0.277 0.277
Loa Loa (eye worm) tubulin alpha 2 0.012 0.1836 0.2882
Echinococcus granulosus inositol monophosphatase 1 0.0023 0.0218 0.0218
Echinococcus multilocularis Tubulin beta 2C chain 0.0243 0.3904 0.3904
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0018 0.0128 0.0128
Echinococcus multilocularis Tubulin beta 2C chain 0.0243 0.3904 0.3904
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0017 0.0104 0.0122
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 38. C. elegans sup-9 ortholog 0.0019 0.0144 0.0247
Echinococcus granulosus TWiK family of potassium channels protein 7 0.0019 0.0144 0.0144
Echinococcus granulosus para nitrobenzyl esterase 0.0012 0.0025 0.0025
Echinococcus granulosus tubulin alpha 3 chain 0.0176 0.277 0.277
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0012 0.0025 0.0025
Loa Loa (eye worm) carboxylesterase 0.0012 0.0025 0.004
Leishmania major cytochrome p450-like protein 0.0033 0.0374 0.0889
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0073 0.1042 0.2622
Schistosoma mansoni hypothetical protein 0.002 0.0165 0.0165
Trypanosoma brucei zeta tubulin, putative 0.0056 0.0759 0.1883
Schistosoma mansoni transcription factor LCR-F1 0.0034 0.0402 0.0402
Brugia malayi acetyltransferase, GNAT family protein 0.0226 0.3623 0.6214
Loa Loa (eye worm) hypothetical protein 0.0019 0.0144 0.0226
Loa Loa (eye worm) PDE1B protein 0.0106 0.1607 0.2524
Echinococcus granulosus acetylcholinesterase 0.0071 0.1011 0.1011
Schistosoma mansoni lipoxygenase 0.0105 0.1581 0.1581
Trypanosoma brucei alpha tubulin 0.0176 0.277 0.7072
Echinococcus granulosus tubulin alpha chain 0.0176 0.277 0.277
Echinococcus multilocularis survival motor neuron protein 1 0.0358 0.583 0.583
Schistosoma mansoni inositol monophosphatase 0.0023 0.0218 0.0218
Entamoeba histolytica ubiquitin-conjugating enzyme family protein 0.0026 0.0264 0.0604
Leishmania major calcium/potassium channel (CAKC), putative 0.0019 0.0144 0.0295
Mycobacterium ulcerans beta-lactamase 0.0062 0.0866 0.6725
Brugia malayi Carboxylesterase family protein 0.0071 0.1011 0.1735
Echinococcus multilocularis tubulin alpha 1C chain 0.0176 0.277 0.277
Trichomonas vaginalis DNA helicase recq, putative 0.0019 0.0139 0.0294
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0047 0.0613 0.0613
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.002 0.0165 0.0165
Schistosoma mansoni hypothetical protein 0.0043 0.054 0.054
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0012 0.0025 0.0025
Loa Loa (eye worm) calcium channel 0.009 0.133 0.2089
Loa Loa (eye worm) hypothetical protein 0.0019 0.0144 0.0226
Schistosoma mansoni acetylcholinesterase 0.0012 0.0025 0.0025
Echinococcus granulosus potassium channel subfamily K 8 0.0019 0.0144 0.0144
Mycobacterium tuberculosis Conserved protein 0.0062 0.0866 0.1303
Trichomonas vaginalis alpha-glucosidase, putative 0.0023 0.0219 0.0499
Echinococcus granulosus calcium activated potassium channel variant 0.0019 0.0144 0.0144
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0036 0.0433 0.0433
Onchocerca volvulus 0.0019 0.0144 0.0533
Loa Loa (eye worm) hypothetical protein 0.0019 0.0144 0.0226
Echinococcus multilocularis neuroligin 0.0012 0.0025 0.0025
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0043 0.0552 0.0552
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0017 0.0104 0.0122
Onchocerca volvulus 0.0019 0.0144 0.0533
Mycobacterium leprae Probable lipase LipE 0.0062 0.0866 0.4867
Loa Loa (eye worm) hypothetical protein 0.012 0.1836 0.2882
Loa Loa (eye worm) CYP4Cod1 0.0033 0.0374 0.0587
Trypanosoma brucei alpha tubulin 0.0176 0.277 0.7072
Trypanosoma brucei alpha tubulin 0.0176 0.277 0.7072
Echinococcus multilocularis Tubulin beta 2C chain 0.0243 0.3904 0.3904
Brugia malayi Bromodomain containing protein 0.0026 0.0253 0.0434
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0043 0.0552 0.0948
Loa Loa (eye worm) hypothetical protein 0.0019 0.0144 0.0226
Schistosoma mansoni tubulin subunit gamma 0.0128 0.1977 0.1977
Leishmania major delta tubulin, putative 0.0056 0.0759 0.1883
Echinococcus multilocularis 0.0017 0.0104 0.0104
Trichomonas vaginalis tubulin alpha chain, putative 0.0243 0.3904 1
Trypanosoma cruzi epsilon tubulin, putative 0.0128 0.1977 0.4949
Leishmania major beta tubulin 0.0243 0.3904 1
Loa Loa (eye worm) isocitrate dehydrogenase 0.002 0.0165 0.0259
Leishmania major alpha tubulin 0.0176 0.277 0.7072
Trypanosoma cruzi trypanothione reductase, putative 0.0045 0.0583 0.1299
Giardia lamblia Hypothetical protein 0.0019 0.0144 0.0147
Trypanosoma brucei beta tubulin 0.0128 0.1977 0.5025
Leishmania major alpha tubulin 0.0176 0.277 0.7072
Echinococcus multilocularis twik family of potassium channels 0.0019 0.0144 0.0144
Trypanosoma cruzi alpha tubulin, putative 0.0176 0.277 0.7028
Trichomonas vaginalis tubulin beta chain, putative 0.0176 0.277 0.7075
Schistosoma mansoni tubulin subunit beta 0.0243 0.3904 0.3904
Mycobacterium tuberculosis Probable dehydrogenase 0.0103 0.1555 0.2371
Schistosoma mansoni gliotactin 0.0012 0.0025 0.0025
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0219 0.0343
Trichomonas vaginalis tubulin epsilon chain, putative 0.0176 0.277 0.7075
Trichomonas vaginalis tubulin gamma chain, putative 0.0056 0.0759 0.1892
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0018 0.0128 0.0128
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0042 0.0528 0.0905
Schistosoma mansoni loxhd1 0.0025 0.0245 0.0245
Loa Loa (eye worm) hypothetical protein 0.0064 0.0899 0.1412
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0043 0.0552 0.0552
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0047 0.0613 0.1375
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0018 0.0124 0.0245
Brugia malayi cytoplasmic intermediate filament protein 0.0013 0.0038 0.0065
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.002 0.0165 0.0165
Leishmania major beta tubulin 0.0243 0.3904 1
Brugia malayi Melibiase family protein 0.0043 0.0552 0.0947
Plasmodium vivax ubiquitin-conjugating enzyme E2 N, putative 0.0026 0.0264 0.0604
Echinococcus multilocularis Tubulin beta 2C chain 0.0243 0.3904 0.3904
Toxoplasma gondii alpha-tubulin I, putative 0.0176 0.277 0.7072
Brugia malayi glutathione reductase 0.0045 0.0583 0.1001
Schistosoma mansoni twik family of potassium channels-related 0.0019 0.0144 0.0144
Loa Loa (eye worm) hypothetical protein 0.0058 0.0791 0.1241
Leishmania major beta tubulin 0.0243 0.3904 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0144 0.0226
Loa Loa (eye worm) hypothetical protein 0.0019 0.0144 0.0226
Brugia malayi hypothetical protein 0.0025 0.0245 0.042
Loa Loa (eye worm) hypothetical protein 0.0019 0.0144 0.0226
Leishmania major ion transport protein-like protein 0.0019 0.0144 0.0295
Echinococcus granulosus tubulin subunit TubB 0.0176 0.277 0.277
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0177 0.2795 0.714
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0018 0.0128 0.0128
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0023 0.0218 0.0487
Mycobacterium ulcerans ion transport protein 0.0019 0.0144 0.0948
Loa Loa (eye worm) hypothetical protein 0.0011 0.0017 0.0026
Echinococcus multilocularis Tubulin alpha 1 chain 0.0176 0.277 0.277
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0016 0.0088 0.015
Trichomonas vaginalis tubulin, putative 0.0073 0.1042 0.2622
Echinococcus multilocularis para nitrobenzyl esterase 0.0012 0.0025 0.0025
Brugia malayi Glycosyl hydrolases family 31 protein 0.0023 0.0219 0.0375
Mycobacterium tuberculosis Probable oxidoreductase 0.0115 0.1749 0.2671
Trypanosoma brucei beta tubulin 0.0243 0.3904 1
Loa Loa (eye worm) acetylcholinesterase 1 0.0071 0.1011 0.1588
Toxoplasma gondii beta tubulin 0.0243 0.3904 1
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0016 0.0088 0.015
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.002 0.0165 0.0203
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0065 0.0923 0.0923
Loa Loa (eye worm) hypothetical protein 0.0196 0.3105 0.4876
Plasmodium falciparum LCCL domain-containing protein 0.0025 0.0245 0.0556
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0062 0.0866 0.0866
Echinococcus multilocularis calcium activated potassium channel variant 0.0019 0.0144 0.0144
Brugia malayi ubiquitin conjugating enzyme protein 13 0.0026 0.0264 0.0452
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0086 0.1276 0.7249
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0017 0.0104 0.0122
Schistosoma mansoni alpha tubulin 0.0176 0.277 0.277
Giardia lamblia Histone acetyltransferase GCN5 0.0061 0.0849 0.1994
Trypanosoma cruzi calcium-activated potassium channel, putative 0.0019 0.0144 0.0147
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0086 0.1276 0.1938
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0086 0.1276 1
Loa Loa (eye worm) cytochrome P450 family protein 0.0033 0.0374 0.0587
Treponema pallidum fructose-bisphosphate aldolase 0.0177 0.2795 1
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0047 0.0613 0.0613
Echinococcus multilocularis isocitrate dehydrogenase 0.002 0.0165 0.0165
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0017 0.0104 0.063
Loa Loa (eye worm) hypothetical protein 0.0019 0.0144 0.0226
Plasmodium falciparum flap endonuclease 1 0.0018 0.0124 0.0245
Brugia malayi Tubulin alpha-2 chain 0.0176 0.277 0.4751
Brugia malayi beta-lactamase family protein 0.0062 0.0866 0.1485
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0047 0.0613 0.1375
Loa Loa (eye worm) hypothetical protein 0.0019 0.0144 0.0226
Brugia malayi Glycosyl hydrolases family 31 protein 0.0106 0.16 0.2745
Loa Loa (eye worm) hypothetical protein 0.0095 0.142 0.2229
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0115 0.1749 0.2671
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0064 0.0899 0.1412
Plasmodium falciparum thioredoxin reductase 0.0016 0.0088 0.015
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0023 0.0219 0.0343
Echinococcus granulosus twik family of potassium channels 0.0019 0.0144 0.0144
Loa Loa (eye worm) hypothetical protein 0.0019 0.0144 0.0226
Brugia malayi Twik (KCNK-like) family of potasium channels, alpha subunit 40 0.0019 0.0144 0.0247
Brugia malayi hypothetical protein 0.0061 0.0854 0.1465
Onchocerca volvulus 0.0143 0.2232 0.9921
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0103 0.1552 0.3937
Leishmania major beta tubulin 0.0243 0.3904 1
Schistosoma mansoni lamin 0.0024 0.0222 0.0222
Trichomonas vaginalis bromodomain-containing protein, putative 0.0067 0.0942 0.2363
Echinococcus multilocularis beta tubulin 0.0243 0.3904 0.3904
Loa Loa (eye worm) potassium voltage-gated channel subfamily Q member 5 0.0019 0.0144 0.0226
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0036 0.0433 0.1042
Plasmodium falciparum histone acetyltransferase GCN5 0.0061 0.0849 0.2114
Onchocerca volvulus 0.0019 0.0144 0.0533
Loa Loa (eye worm) carboxylesterase 0.0012 0.0025 0.004
Schistosoma mansoni calcium-activated potassium channel 0.039 0.6368 0.6368
Echinococcus multilocularis tubulin subunit beta 0.0243 0.3904 0.3904
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0043 0.0552 0.1359
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0018 0.0128 0.0128
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.002 0.0165 0.0165
Brugia malayi Bloom's syndrome protein homolog 0.0019 0.0139 0.0239
Onchocerca volvulus 0.0024 0.0222 0.0886
Onchocerca volvulus 0.0019 0.0144 0.0533
Toxoplasma gondii PHD-finger domain-containing protein 0.002 0.016 0.0337
Leishmania major alpha tubulin 0.0176 0.277 0.7072
Echinococcus multilocularis tubulin alpha 3 chain 0.0176 0.277 0.277
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0017 0.0117 0.0117
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0065 0.0916 0.0916
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0062 0.0866 0.1303
Schistosoma mansoni jumonji domain containing protein 0.0052 0.0697 0.0697
Echinococcus multilocularis serotonin transporter 0.0058 0.0791 0.0791
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0023 0.0219 0.0499
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 12 0.0019 0.0144 0.0247
Loa Loa (eye worm) hypothetical protein 0.0023 0.0215 0.0338
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0115 0.1749 1
Echinococcus granulosus tubulin alpha 0.0128 0.1977 0.1977
Leishmania major epsilon tubulin, putative 0.0128 0.1977 0.5025
Echinococcus multilocularis lysosomal alpha glucosidase 0.0106 0.16 0.16
Trichomonas vaginalis tubulin beta chain, putative 0.0176 0.277 0.7075
Echinococcus granulosus lysine specific demethylase 5A 0.0024 0.0231 0.0231
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0219 0.0343
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0106 0.1607 0.2757
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0043 0.054 0.054
Onchocerca volvulus Alhambra homolog 0.002 0.016 0.0606
Schistosoma mansoni jumonji/arid domain-containing protein 0.0024 0.0231 0.0231
Schistosoma mansoni alpha tubulin 0.0176 0.277 0.277
Echinococcus granulosus Tubulin alpha 1 chain 0.0176 0.277 0.277
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0016 0.0088 0.015
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0023 0.0218 0.0497
Brugia malayi jmjC domain containing protein 0.0024 0.0231 0.0396
Loa Loa (eye worm) cytochrome P450 family protein 0.0033 0.0374 0.0587
Echinococcus granulosus arachidonate 5 lipoxygenase 0.015 0.2337 0.2337
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 28 0.0019 0.0144 0.0247
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0115 0.1749 0.2671
Leishmania major cytochrome p450-like protein 0.0017 0.0104 0.0193
Brugia malayi jmjC domain containing protein 0.0065 0.0923 0.1583
Echinococcus multilocularis tubulin alpha chain 0.0176 0.277 0.277
Loa Loa (eye worm) beta-tubulin 0.0243 0.3904 0.6131
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0128 0.1977 0.5025
Leishmania major alpha tubulin 0.0176 0.277 0.7072
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0024 0.0222 0.0349
Echinococcus multilocularis tubulin alpha 0.0128 0.1977 0.1977
Entamoeba histolytica calcium-gated potassium channel protein, putative 0.0019 0.0144 0.0295
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0023 0.0218 0.0342
Loa Loa (eye worm) hypothetical protein 0.0358 0.583 0.9156
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0019 0.0144 0.0305
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0031 0.0349 0.0825
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0759 0.1892
Mycobacterium leprae conserved hypothetical protein 0.0062 0.0866 0.4867
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0177 0.2795 0.714
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.009 0.133 0.133
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0042 0.0528 0.1286
Echinococcus multilocularis tubulin alpha chain 0.0176 0.277 0.277
Mycobacterium leprae cell division protein FtsZ 0.0056 0.0759 0.4244
Plasmodium vivax multidomain scavenger receptor, putative 0.0025 0.0245 0.0556
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0017 0.0104 0.0122
Trypanosoma brucei epsilon tubulin 0.0128 0.1977 0.5025
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0011 0.0017 0.0017
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0177 0.2795 0.714
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0017 0.0104 0.0122
Echinococcus multilocularis lysine specific demethylase 5A 0.0024 0.0231 0.0231
Echinococcus granulosus neutral alpha glucosidase AB 0.0023 0.0219 0.0219
Loa Loa (eye worm) hypothetical protein 0.0062 0.0866 0.136
Trypanosoma brucei calcium-activated potassium channel, putative 0.0019 0.0144 0.0295
Toxoplasma gondii ion channel protein 0.0019 0.0144 0.0295
Loa Loa (eye worm) hypothetical protein 0.0058 0.0791 0.1241
Leishmania major alpha tubulin 0.0176 0.277 0.7072
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0515 0.8462 0.8462
Entamoeba histolytica tubulin alpha-1 chain 0.0176 0.277 0.7072
Loa Loa (eye worm) hypothetical protein 0.0019 0.0144 0.0226
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.004
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0065 0.0923 0.0923
Toxoplasma gondii PHD-finger domain-containing protein 0.002 0.016 0.0337
Brugia malayi Carboxylesterase family protein 0.0012 0.0025 0.0043
Echinococcus granulosus GPCR family 2 0.002 0.0165 0.0165
Onchocerca volvulus 0.0062 0.0866 0.378
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 32 0.0019 0.0144 0.0247
Plasmodium vivax tubulin epsilon chain, putative 0.0128 0.1977 0.5025
Echinococcus granulosus tubulin alpha chain 0.0176 0.277 0.277
Echinococcus multilocularis beta LACTamase domain containing family member 0.0062 0.0866 0.0866
Echinococcus multilocularis lamin dm0 0.0024 0.0222 0.0222
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.002 0.0165 0.0165
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0047 0.0613 0.0613
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0042 0.0528 0.1286
Onchocerca volvulus 0.0019 0.0144 0.0533
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0016 0.0088 0.0088
Plasmodium vivax flap endonuclease 1, putative 0.0018 0.0124 0.0245
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0056 0.0759 0.1883
Leishmania major hypothetical protein, conserved 0.0019 0.0144 0.0295
Mycobacterium ulcerans transmembrane cation transporter 0.0019 0.0144 0.0948
Plasmodium falciparum glutathione reductase 0.0045 0.0583 0.143
Plasmodium falciparum ubiquitin-conjugating enzyme E2 N, putative 0.0026 0.0264 0.0604
Echinococcus granulosus PHD finger protein rhinoceros 0.002 0.016 0.016
Brugia malayi Cell division protein ftsZ 0.0056 0.0759 0.1302
Leishmania major beta tubulin 0.0243 0.3904 1
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0017 0.0104 0.0043
Echinococcus multilocularis acetylcholinesterase 0.0071 0.1011 0.1011
Leishmania major alpha tubulin 0.0176 0.277 0.7072
Mycobacterium ulcerans cell division protein FtsZ 0.0056 0.0759 0.5869
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0016 0.0088 0.0499
Schistosoma mansoni hypothetical protein 0.0017 0.0104 0.0104
Loa Loa (eye worm) tubulin alpha chain 0.0176 0.277 0.435
Loa Loa (eye worm) voltage-dependent calcium channel 0.0031 0.0349 0.0548
Brugia malayi isocitrate dehydrogenase 0.002 0.0165 0.0283
Trypanosoma brucei cytochrome P450, putative 0.0033 0.0374 0.0889
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 39A 0.0019 0.0144 0.0247
Echinococcus granulosus geminin 0.0483 0.7924 0.7924
Mycobacterium tuberculosis Cell division protein FtsZ 0.0056 0.0759 0.1137
Toxoplasma gondii thioredoxin reductase 0.0045 0.0583 0.143
Echinococcus granulosus Tubulin beta 2C chain 0.0243 0.3904 0.3904
Echinococcus granulosus tubulin beta 4A class IVa 0.0243 0.3904 0.3904
Trypanosoma brucei beta tubulin 0.0243 0.3904 1
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0067 0.0942 0.2354
Schistosoma mansoni flap endonuclease-1 0.0016 0.0095 0.0095
Treponema pallidum cell division protein FtsZ 0.0056 0.0759 0.2638
Loa Loa (eye worm) inositol-1 0.0023 0.0218 0.0343
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0023 0.0219 0.0488
Loa Loa (eye worm) hypothetical protein 0.0019 0.0144 0.0226
Echinococcus multilocularis voltage dependent calcium channel 0.009 0.133 0.133
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0018 0.0128 0.0128
Loa Loa (eye worm) hypothetical protein 0.0019 0.0144 0.0226
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0047 0.0613 0.0613
Mycobacterium leprae putative cytochrome p450 0.0017 0.0104 0.0434
Leishmania major hypothetical protein, conserved 0.0019 0.0144 0.0295
Loa Loa (eye worm) solute carrier family 6 member 4 0.0058 0.0791 0.1241
Loa Loa (eye worm) cytochrome P450 family protein 0.0053 0.0716 0.1125
Brugia malayi tubulin alpha chain - mouse 0.0176 0.277 0.4751
Trichomonas vaginalis tubulin gamma chain, putative 0.0243 0.3904 1
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0017 0.0104 0.0122
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0017 0.0104 0.0122
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0033 0.0374 0.2788
Echinococcus granulosus carboxylesterase 5A 0.0071 0.1011 0.1011
Brugia malayi tubulin alpha-2 chain 0.0176 0.277 0.4751
Loa Loa (eye worm) hypothetical protein 0.0019 0.0144 0.0226
Echinococcus multilocularis tubulin epsilon chain 0.0128 0.1977 0.1977
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0017 0.0104 0.0193
Echinococcus granulosus small conductance calcium activated potassium 0.039 0.6368 0.6368
Brugia malayi beta-tubulin, identical 0.0243 0.3904 0.6696
Plasmodium falciparum phd finger protein, putative 0.002 0.016 0.0337
Brugia malayi Tubulin gamma chain 0.0128 0.1977 0.339
Brugia malayi PHD-finger family protein 0.002 0.016 0.0275
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.012 0.1836 0.4667
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0017 0.0104 0.063
Trichomonas vaginalis DNA helicase recq1, putative 0.0019 0.0139 0.0294
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.002 0.0165 0.0165
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 21 0.0019 0.0144 0.0247
Loa Loa (eye worm) cytochrome P450 0.0017 0.0104 0.0163
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0067 0.0942 0.2354
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0017 0.0104 0.063
Leishmania major hypothetical protein, conserved 0.0062 0.0866 0.2159
Echinococcus granulosus peroxisome assembly protein 26 0.0176 0.277 0.277
Loa Loa (eye worm) tubulin alpha-2 chain 0.0176 0.277 0.435
Echinococcus granulosus tubulin alpha 1C chain 0.0176 0.277 0.277
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0062 0.0866 0.1485
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0103 0.1555 0.2371
Plasmodium falciparum potassium channel 0.0019 0.0144 0.0295
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.015 0.2337 0.2337
Treponema pallidum NADH oxidase 0.0016 0.0088 0.0211
Brugia malayi latrophilin 2 splice variant baaae 0.0044 0.0559 0.0959
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0759 0.1892
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0017 0.0104 0.063
Loa Loa (eye worm) hypothetical protein 0.0019 0.0144 0.0226
Loa Loa (eye worm) hypothetical protein 0.0043 0.0552 0.0867
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0016 0.0088 0.015
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0065 0.0916 0.0916
Loa Loa (eye worm) serotonin transporter b 0.0058 0.0791 0.1241
Echinococcus granulosus tubulin alpha chain 0.0176 0.277 0.277
Trichomonas vaginalis tubulin epsilon chain, putative 0.0056 0.0759 0.1892
Loa Loa (eye worm) hypothetical protein 0.0047 0.0613 0.0962
Loa Loa (eye worm) hypothetical protein 0.0103 0.1552 0.2438
Schistosoma mansoni hypothetical protein 0.0034 0.0402 0.0402
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0016 0.0088 1
Echinococcus granulosus tubulin subunit beta 0.0243 0.3904 0.3904
Schistosoma mansoni calcium-activated potassium channel 0.0019 0.0144 0.0144
Trypanosoma brucei epsilon tubulin 0.0128 0.1977 0.5025
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0017 0.0104 0.063
Loa Loa (eye worm) hypothetical protein 0.0044 0.0559 0.0878
Mycobacterium tuberculosis Probable reductase 0.0103 0.1555 0.2371
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0016 0.0088 0.0499
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0062 0.0866 0.6725
Echinococcus multilocularis beta tubulin 0.0243 0.3904 0.3904
Giardia lamblia PHD finger protein 15 0.002 0.016 0.019
Schistosoma mansoni hypothetical protein 0.0073 0.105 0.105
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0397 0.6478 1
Schistosoma mansoni twik family of potassium channels-related 0.0019 0.0144 0.0144
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0013 0.0038 0.0059
Schistosoma mansoni twik family of potassium channels-related 0.0019 0.0144 0.0144
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.009 0.133 0.133
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.009 0.133 0.2281
Echinococcus multilocularis Tubulin alpha 1 chain 0.0176 0.277 0.277
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0017 0.0104 0.063
Trypanosoma cruzi tubulin gamma chain 0.0128 0.1977 0.4949
Echinococcus granulosus lipoxygenase domain containing protein 0.0025 0.0245 0.0245
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0017 0.0104 0.0122
Trypanosoma cruzi ion transport protein, putative 0.0019 0.0144 0.0147
Loa Loa (eye worm) hypothetical protein 0.0062 0.0866 0.136
Loa Loa (eye worm) hypothetical protein 0.002 0.016 0.0251
Loa Loa (eye worm) hypothetical protein 0.0011 0.0009 0.0015
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.002 0.016 0.016
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0106 0.1607 0.1607
Toxoplasma gondii ABC1 family protein 0.0062 0.0866 0.2159
Onchocerca volvulus 0.0019 0.0144 0.0533
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0042 0.0528 0.1286
Trichomonas vaginalis alpha-glucosidase, putative 0.0023 0.0219 0.0499
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0018 0.0128 0.0255
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0026 0.0264 0.0614
Onchocerca volvulus 0.0019 0.0144 0.0533
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0012 0.0029 0.0033
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0065 0.0916 0.0916
Mycobacterium tuberculosis Probable hydrolase 0.0062 0.0866 0.1303
Trichomonas vaginalis tubulin epsilon chain, putative 0.0243 0.3904 1
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.009 0.133 0.133
Leishmania major ubiquitin-conjugating enzyme e2, putative 0.0026 0.0264 0.0604
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0088 0.015
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0103 0.1555 0.2371
Trypanosoma cruzi cytochrome P450, putative 0.0033 0.0374 0.075
Loa Loa (eye worm) hypothetical protein 0.0019 0.0144 0.0226
Echinococcus granulosus tubulin alpha chain 0.0176 0.277 0.277
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0012 0.0025 0.0025
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0012 0.0018 0.0031
Onchocerca volvulus 0.0024 0.0222 0.0886
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0023 0.0219 0.0488
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0017 0.0104 0.063
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0031 0.0349 0.0685
Trichomonas vaginalis tubulin epsilon chain, putative 0.0176 0.277 0.7075
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0018 0.0128 0.0128
Leishmania major beta tubulin 0.0243 0.3904 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.002 0.0165 0.0165
Echinococcus multilocularis RUN 0.0025 0.0245 0.0245
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.004
Treponema pallidum sodium- and chloride- dependent transporter 0.0058 0.0791 0.2752
Schistosoma mansoni neuroligin 3 (S09 family) 0.0012 0.0025 0.0025
Echinococcus granulosus acetylcholinesterase 0.0071 0.1011 0.1011
Trypanosoma cruzi epsilon tubulin, putative 0.0128 0.1977 0.4949
Loa Loa (eye worm) tubulin alpha 2 0.012 0.1836 0.2882
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0177 0.2795 0.714
Toxoplasma gondii transporter, cation channel family protein 0.0031 0.0349 0.0825
Loa Loa (eye worm) alpha-tubulin isotype 2 0.012 0.1836 0.2882
Trypanosoma brucei ubiquitin-protein ligase, putative 0.0026 0.0264 0.0604
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0042 0.0528 0.0528
Mycobacterium ulcerans esterase/lipase LipP 0.0062 0.0866 0.6725
Echinococcus multilocularis hypothetical protein 0.0176 0.277 0.277
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0017 0.0104 0.0122
Echinococcus multilocularis potassium channel subfamily K 0.0019 0.0144 0.0144
Mycobacterium tuberculosis Conserved protein 0.0062 0.0866 0.1303
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0016 0.0088 0.015
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0016 0.0088 0.015
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 7 0.0019 0.0144 0.0247
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.002 0.0165 0.035
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.009 0.133 0.133
Giardia lamblia Flap structure-specific endonuclease 0.0018 0.0124 0.0096
Loa Loa (eye worm) BEN-1 protein 0.0243 0.3904 0.6131
Brugia malayi Tubulin alpha-2 chain 0.0176 0.277 0.4751
Echinococcus granulosus Tubulin beta 2C chain 0.0243 0.3904 0.3904
Plasmodium falciparum tubulin beta chain 0.0243 0.3904 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0076 0.0119
Brugia malayi Tubulin alpha chain 0.0176 0.277 0.4751
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 24 0.0019 0.0144 0.0247
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0042 0.0528 0.1153
Schistosoma mansoni calcium-activated potassium channel 0.0019 0.0144 0.0144
Echinococcus granulosus intermediate filament protein 0.0024 0.0222 0.0222
Loa Loa (eye worm) uncoordinated protein 58 0.0019 0.0144 0.0226
Echinococcus granulosus tubulin alpha chain 0.0176 0.277 0.277
Leishmania major beta tubulin 0.0243 0.3904 1
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0012 0.0029 0.0033
Brugia malayi Carboxylesterase family protein 0.0012 0.0025 0.0043
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0058 0.0791 0.1356
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 35 0.0019 0.0144 0.0247
Echinococcus multilocularis tubulin beta 1 chain 0.0243 0.3904 0.3904
Plasmodium vivax tubulin gamma chain, putative 0.0128 0.1977 0.5025
Leishmania major beta tubulin 0.0243 0.3904 1
Brugia malayi Latrophilin receptor protein 2 0.002 0.0165 0.0282
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0613 0.1514
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0065 0.0916 0.0916
Brugia malayi hypothetical protein 0.0025 0.0245 0.042
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0017 0.0104 0.0122
Schistosoma mansoni tubulin subunit delta 0.0056 0.0759 0.0759
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0017 0.0104 0.063
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0016 0.0088 0.015
Loa Loa (eye worm) tubulin alpha 2 0.0047 0.0618 0.097
Schistosoma mansoni hypothetical protein 0.0044 0.0559 0.0559
Loa Loa (eye worm) TWK-28 protein 0.0019 0.0144 0.0226
Toxoplasma gondii hypothetical protein 0.0027 0.0286 0.0662
Plasmodium falciparum tubulin gamma chain 0.0128 0.1977 0.5025
Loa Loa (eye worm) TWK-7 protein 0.0019 0.0144 0.0226
Giardia lamblia Gamma tubulin 0.0128 0.1977 0.4949
Trichomonas vaginalis D-aminoacylase, putative 0.0062 0.0866 0.2168
Plasmodium vivax potassium channel, putative 0.0019 0.0144 0.0295
Trichomonas vaginalis tubulin, putative 0.0056 0.0759 0.1892
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0045 0.0583 0.0865
Echinococcus granulosus Tubulin beta 2C chain 0.0243 0.3904 0.3904
Schistosoma mansoni alpha-glucosidase 0.0091 0.1353 0.1353
Trypanosoma brucei tubulin delta chain 0.0056 0.0759 0.1883
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0019 0.0144 0.0305
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0018 0.0124 0.0245
Brugia malayi Cytochrome P450 family protein 0.0053 0.0716 0.1229
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0012 0.0025 0.0025
Trypanosoma brucei alpha tubulin 0.0176 0.277 0.7072
Brugia malayi beta-lactamase family protein 0.0062 0.0866 0.1485
Entamoeba histolytica hypothetical protein 0.0034 0.0402 0.0962
Trichomonas vaginalis tubulin gamma chain, putative 0.0128 0.1977 0.503
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0023 0.0218 0.1543
Trichomonas vaginalis glutathione reductase, putative 0.0016 0.0088 0.0161
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.002 0.0165 0.035
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0017 0.0104 0.063
Brugia malayi Isocitrate dehydrogenase 0.002 0.0165 0.0283
Toxoplasma gondii NADPH-glutathione reductase 0.0016 0.0088 0.015
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0065 0.0916 0.0916
Loa Loa (eye worm) hypothetical protein 0.0027 0.0286 0.0449
Echinococcus granulosus tubulin beta 1 chain 0.0243 0.3904 0.3904
Brugia malayi Ubiquitin conjugating enzyme protein 13 0.0026 0.0264 0.0452
Schistosoma mansoni tubulin subunit epsilon 0.0128 0.1977 0.1977
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0013 0.0035 0.0014
Loa Loa (eye worm) tubulin beta-4 chain 0.0243 0.3904 0.6131
Loa Loa (eye worm) tubulin gamma chain 0.0128 0.1977 0.3104
Echinococcus multilocularis small conductance calcium activated potassium 0.039 0.6368 0.6368
Loa Loa (eye worm) doublecortin family protein 0.0025 0.0245 0.0384
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0106 0.1607 0.1607
Brugia malayi Doublecortin family protein 0.0025 0.0245 0.042
Leishmania major zeta tubulin, putative 0.0056 0.0759 0.1883
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0036 0.0433 0.0433
Toxoplasma gondii isocitrate dehydrogenase 0.002 0.0165 0.035
Echinococcus granulosus ubiquitin specific protease 41 0.0047 0.0613 0.0613
Onchocerca volvulus 0.0058 0.0791 0.3441
Trichomonas vaginalis tubulin, putative 0.0073 0.1042 0.2622
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0056 0.0759 0.1883
Brugia malayi Cytochrome P450 family protein 0.0033 0.0374 0.0641
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0036 0.0433 0.1042
Mycobacterium ulcerans lipase LipD 0.0062 0.0866 0.6725
Loa Loa (eye worm) flap endonuclease-1 0.0018 0.0124 0.0195
Echinococcus multilocularis ubiquitin specific protease 41 0.0047 0.0613 0.0613
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 13 0.0019 0.0144 0.0247
Schistosoma mansoni inositol monophosphatase 0.0023 0.0218 0.0218
Trypanosoma brucei isocitrate dehydrogenase, putative 0.002 0.0165 0.035
Brugia malayi Tubulin beta chain 0.0056 0.0759 0.1302
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0058 0.0791 0.0791
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0177 0.2795 0.714
Echinococcus multilocularis flap endonuclease 1 0.0018 0.0124 0.0124
Loa Loa (eye worm) tubulin alpha-3 chain 0.0103 0.1552 0.2438
Trypanosoma cruzi hypothetical protein, conserved 0.0062 0.0866 0.204
Plasmodium vivax thioredoxin reductase, putative 0.0045 0.0583 0.143
Echinococcus multilocularis Tubulin alpha 1 chain 0.0176 0.277 0.277
Loa Loa (eye worm) hypothetical protein 0.0176 0.277 0.435
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0042 0.0528 0.1153
Trichomonas vaginalis flap endonuclease-1, putative 0.0018 0.0124 0.0255
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.009 0.133 0.133
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0017 0.0104 0.0122
Leishmania major alpha tubulin 0.0176 0.277 0.7072
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0012 0.0018 0.0031
Entamoeba histolytica tubulin family protein 0.0243 0.3904 1
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0017 0.0104 0.0122
Echinococcus multilocularis ubiquitin conjugating enzyme E2 N 0.0026 0.0264 0.0264
Echinococcus multilocularis GPCR, family 2 0.002 0.0165 0.0165
Onchocerca volvulus 0.0062 0.0866 0.378
Loa Loa (eye worm) hypothetical protein 0.0018 0.0128 0.0201
Loa Loa (eye worm) BEN-1 protein 0.0243 0.3904 0.6131
Plasmodium vivax tubulin beta chain, putative 0.0243 0.3904 1
Trypanosoma brucei PAB1-binding protein , putative 0.0095 0.142 0.3588
Echinococcus multilocularis acetylcholinesterase 0.0071 0.1011 0.1011
Onchocerca volvulus 0.0062 0.0866 0.378
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0047 0.0613 0.1514
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0026 0.0264 0.0461
Schistosoma mansoni lamin 0.0024 0.0222 0.0222
Schistosoma mansoni hypothetical protein 0.0025 0.0245 0.0245
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 17 0.0019 0.0144 0.0247
Giardia lamblia Epsilon tubulin 0.0056 0.0759 0.1759
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0017 0.0104 0.063
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0017 0.0104 0.063
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0016 0.0088 0.0097
Trypanosoma brucei trypanothione reductase 0.0045 0.0583 0.143
Leishmania major alpha tubulin 0.0176 0.277 0.7072
Leishmania major beta tubulin 0.0243 0.3904 1
Brugia malayi hypothetical protein 0.0095 0.142 0.2435
Echinococcus granulosus thioredoxin glutathione reductase 0.0045 0.0583 0.0583
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0016 0.0088 0.015
Schistosoma mansoni alpha tubulin 0.0176 0.277 0.277
Trichomonas vaginalis tubulin beta chain, putative 0.0176 0.277 0.7075
Loa Loa (eye worm) latrophilin receptor protein 2 0.002 0.0165 0.0259
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0017 0.0104 0.063
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0103 0.1555 0.2371
Trichomonas vaginalis alpha-glucosidase, putative 0.0023 0.0219 0.0499
Toxoplasma gondii isocitrate dehydrogenase 0.002 0.0165 0.035
Echinococcus multilocularis musashi 0.0024 0.0222 0.0222
Echinococcus granulosus potassium channel subfamily K 0.0019 0.0144 0.0144
Trichomonas vaginalis sucrase-isomaltase, putative 0.0023 0.0219 0.0499
Schistosoma mansoni hypothetical protein 0.002 0.0165 0.0165
Loa Loa (eye worm) hypothetical protein 0.0019 0.0144 0.0226
Loa Loa (eye worm) hypothetical protein 0.0043 0.0552 0.0868
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0023 0.0218 0.0487
Loa Loa (eye worm) intermediate filament protein 0.0024 0.0222 0.0349
Brugia malayi Cytochrome P450 family protein 0.0017 0.0104 0.0178
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0062 0.0866 0.1303
Echinococcus multilocularis twik family of potassium channels 0.0019 0.0144 0.0144
Schistosoma mansoni jumonji/arid domain-containing protein 0.0024 0.0231 0.0231
Echinococcus granulosus tubulin delta chain 0.0056 0.0759 0.0759
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0019 0.0144 0.0305
Echinococcus multilocularis TWiK family of potassium channels protein 7 0.0019 0.0144 0.0144
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0088 0.015
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0017 0.0104 0.0122
Echinococcus multilocularis BC026374 protein (S09 family) 0.0012 0.0025 0.0025
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0021 0.0177 0.0858
Loa Loa (eye worm) hypothetical protein 0.0031 0.0349 0.0548
Brugia malayi cytochrome P450 0.0017 0.0104 0.0178
Loa Loa (eye worm) hypothetical protein 0.0019 0.0144 0.0226
Echinococcus granulosus alpha tubulin 0.0176 0.277 0.277
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0017 0.0104 0.0043
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0144 0.0147
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0018 0.0124 0.0096
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0071 0.1011 0.1011
Onchocerca volvulus 0.0043 0.0552 0.2371
Loa Loa (eye worm) MH2 domain-containing protein 0.0153 0.2397 0.3765
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.004
Schistosoma mansoni tubulin subunit beta 0.0243 0.3904 0.3904
Echinococcus multilocularis tubulin delta chain 0.0056 0.0759 0.0759
Loa Loa (eye worm) hypothetical protein 0.0062 0.0866 0.136
Echinococcus multilocularis tubulin subunit TubB 0.0176 0.277 0.277
Giardia lamblia Alpha-tubulin 0.0176 0.277 0.7028
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.009 0.133 0.133
Mycobacterium tuberculosis Probable lipase LipE 0.0062 0.0866 0.1303
Leishmania major alpha tubulin 0.0176 0.277 0.7072
Brugia malayi Carboxylesterase family protein 0.0071 0.1011 0.1735
Echinococcus granulosus lipoxygenase domain containing protein 0.0025 0.0245 0.0245
Trypanosoma cruzi calcium-activated potassium channel, putative 0.0019 0.0144 0.0147
Loa Loa (eye worm) hypothetical protein 0.0062 0.0866 0.136
Echinococcus granulosus RUN 0.0025 0.0245 0.0245
Toxoplasma gondii ubiquitin-conjugating enzyme subfamily protein 0.0026 0.0264 0.0604
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0042 0.0528 0.0528
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0023 0.0218 0.0497
Leishmania major beta tubulin 0.0243 0.3904 1
Schistosoma mansoni rab6-interacting 0.0025 0.0245 0.0245
Schistosoma mansoni tubulin subunit beta 0.0056 0.0759 0.0759
Loa Loa (eye worm) hypothetical protein 0.0019 0.0144 0.0226
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0017 0.0104 0.0122
Echinococcus granulosus peregrin 0.0026 0.0253 0.0253
Loa Loa (eye worm) hypothetical protein 0.0175 0.2769 0.4348
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0023 0.0219 0.0499
Toxoplasma gondii cytochrome p450 superfamily protein 0.0017 0.0104 0.0193
Loa Loa (eye worm) jmjC domain-containing protein 0.0041 0.0517 0.0812
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 45 0.0019 0.0144 0.0247
Schistosoma mansoni tubulin subunit alpha 0.0056 0.0759 0.0759
Brugia malayi Tubulin alpha chain 0.0056 0.0759 0.1302
Schistosoma mansoni intermediate filament proteins 0.0024 0.0222 0.0222
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0226 0.3623 0.3623
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0064 0.0899 0.1542
Brugia malayi Pre-SET motif family protein 0.0018 0.0128 0.022
Trichomonas vaginalis tubulin beta chain, putative 0.0176 0.277 0.7075
Echinococcus granulosus L aminoadipate semialdehyde 0.0043 0.0552 0.0552
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0103 0.1555 0.8877
Loa Loa (eye worm) large conductance calcium-activated potassium channel alpha subunit ai 0.0019 0.0144 0.0226
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0026 0.0264 0.0414
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0016 0.0101 0.0185
Loa Loa (eye worm) hypothetical protein 0.0019 0.0144 0.0226
Trypanosoma cruzi zeta tubulin, putative 0.0056 0.0759 0.1759
Loa Loa (eye worm) jmjC domain-containing protein 0.0024 0.0231 0.0362
Echinococcus granulosus histone lysine methyltransferase setb 0.0018 0.0128 0.0128
Loa Loa (eye worm) hypothetical protein 0.0019 0.0144 0.0226
Onchocerca volvulus 0.0025 0.0245 0.0987
Echinococcus multilocularis lipoxygenase domain containing protein 0.0025 0.0245 0.0245
Trichomonas vaginalis alpha-glucosidase, putative 0.0023 0.0219 0.0499
Plasmodium vivax ataxin-2 like protein, putative 0.0095 0.142 0.3588
Echinococcus granulosus Tubulin alpha 1 chain 0.0176 0.277 0.277
Entamoeba histolytica Flap nuclease, putative 0.0018 0.0124 0.0245
Loa Loa (eye worm) glutathione reductase 0.0045 0.0583 0.0916
Trichomonas vaginalis tubulin alpha chain, putative 0.0073 0.1042 0.2622
Entamoeba histolytica tubulin alpha chain, putative 0.0176 0.277 0.7072
Loa Loa (eye worm) S-phase kinase-associated protein 1A 0.0019 0.0144 0.0226
Toxoplasma gondii ion channel protein 0.0019 0.0144 0.0295
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0047 0.0613 0.1514
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0023 0.0218 0.2587
Toxoplasma gondii beta-tubulin, putative 0.0243 0.3904 1
Brugia malayi hypothetical protein 0.0012 0.0025 0.0043
Schistosoma mansoni voltage-gated cation channel 0.009 0.133 0.133
Giardia lamblia Beta tubulin 0.0243 0.3904 1
Loa Loa (eye worm) tubulin beta chain 0.0056 0.0759 0.1192
Schistosoma mansoni twik family of potassium channels-related 0.0019 0.0144 0.0144
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0067 0.0942 0.2354
Brugia malayi Tubulin beta-1 chain 0.0243 0.3904 0.6696
Brugia malayi beta-lactamase 0.0062 0.0866 0.1485
Echinococcus multilocularis peregrin 0.0026 0.0253 0.0253
Echinococcus granulosus survival motor neuron protein 1 0.0358 0.583 0.583
Leishmania major beta tubulin 0.0243 0.3904 1
Brugia malayi hypothetical protein 0.0358 0.583 1
Echinococcus granulosus beta tubulin 0.0243 0.3904 0.3904
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0016 0.0088 0.015
Echinococcus granulosus lamin dm0 0.0024 0.0222 0.0222
Trichomonas vaginalis penicillin-binding protein, putative 0.0062 0.0866 0.2168
Plasmodium vivax delta tubulin, putative 0.0056 0.0759 0.1883
Loa Loa (eye worm) tubulin beta-1 chain 0.0243 0.3904 0.6131
Schistosoma mansoni twik family of potassium channels-related 0.0019 0.0144 0.0144
Leishmania major alpha tubulin 0.0176 0.277 0.7072
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.002 0.0165 0.035
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0056 0.0759 0.1892
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0047 0.0613 0.1375
Loa Loa (eye worm) hypothetical protein 0.0062 0.0866 0.136
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0177 0.2795 0.714
Echinococcus granulosus lamin 0.0024 0.0222 0.0222
Leishmania major cytochrome p450-like protein 0.0017 0.0104 0.0193
Echinococcus multilocularis PHD finger protein rhinoceros 0.002 0.016 0.016
Brugia malayi Carboxylesterase family protein 0.0012 0.0025 0.0043
Plasmodium vivax tubulin alpha chain, putative 0.0176 0.277 0.7072
Schistosoma mansoni tubulin subunit beta 0.0243 0.3904 0.3904
Loa Loa (eye worm) alpha-tubulin 0.0176 0.277 0.435
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0047 0.0613 0.1505
Leishmania major beta tubulin 0.0243 0.3904 1
Trypanosoma brucei hypothetical protein, conserved 0.0062 0.0866 0.2159
Leishmania major alpha glucosidase II subunit, putative 0.0023 0.0219 0.0488
Echinococcus multilocularis tubulin alpha 1C chain 0.0176 0.277 0.277
Echinococcus multilocularis L aminoadipate semialdehyde 0.0043 0.0552 0.0552
Trypanosoma cruzi calcium/potassium channel (CAKC), putative 0.0019 0.0144 0.0147
Echinococcus multilocularis Tubulin beta 2C chain 0.0243 0.3904 0.3904
Loa Loa (eye worm) hypothetical protein 0.039 0.6368 1
Trypanosoma cruzi PAB1-binding protein , putative 0.0095 0.142 0.349
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 39B 0.0019 0.0144 0.0247
Trichomonas vaginalis tubulin beta chain, putative 0.0243 0.3904 1
Schistosoma mansoni tubulin subunit beta 0.0243 0.3904 0.3904
Plasmodium vivax potassium channel, putative 0.0019 0.0144 0.0295
Plasmodium falciparum ataxin-2 like protein, putative 0.0095 0.142 0.3588
Loa Loa (eye worm) hypothetical protein 0.0071 0.1011 0.1588
Echinococcus granulosus beta tubulin 0.0243 0.3904 0.3904
Echinococcus multilocularis tubulin alpha chain 0.0176 0.277 0.277
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.002 0.0165 0.0165
Leishmania major alpha tubulin 0.0176 0.277 0.7072
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0047 0.0613 0.0613
Echinococcus granulosus serotonin transporter 0.0058 0.0791 0.0791
Onchocerca volvulus 0.0019 0.0144 0.0533
Brugia malayi intermediate filament protein 0.0024 0.0222 0.0381
Loa Loa (eye worm) hypothetical protein 0.0025 0.0245 0.0384
Loa Loa (eye worm) alpha-tubulin 0.0176 0.277 0.435
Brugia malayi alpha-tubulin 0.0176 0.277 0.4751
Loa Loa (eye worm) hypothetical protein 0.0034 0.04 0.0628
Trichomonas vaginalis alpha-glucosidase, putative 0.0023 0.0219 0.0499
Echinococcus multilocularis lamin 0.0024 0.0222 0.0222
Echinococcus multilocularis Polycystic kidney disease protein 0.0025 0.0245 0.0245
Loa Loa (eye worm) hypothetical protein 0.0058 0.0791 0.1241
Loa Loa (eye worm) hypothetical protein 0.0019 0.0144 0.0226
Leishmania major trypanothione reductase 0.0045 0.0583 0.143
Mycobacterium ulcerans hypothetical protein 0.0062 0.0866 0.6725
Loa Loa (eye worm) hypothetical protein 0.0024 0.0222 0.0349
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0034 0.0402 0.0402
Schistosoma mansoni hypothetical protein 0.0483 0.7924 0.7924
Schistosoma mansoni alpha-glucosidase 0.0091 0.1353 0.1353
Leishmania major beta tubulin 0.0243 0.3904 1
Trichomonas vaginalis D-aminoacylase, putative 0.0062 0.0866 0.2168
Echinococcus granulosus jumonji domain containing protein 0.0028 0.0291 0.0291
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0047 0.0613 0.1505
Brugia malayi hypothetical protein 0.0019 0.0144 0.0247
Schistosoma mansoni hypothetical protein 0.002 0.0165 0.0165
Plasmodium vivax SET domain protein, putative 0.0018 0.0128 0.0255
Echinococcus multilocularis tubulin gamma 1 chain 0.0128 0.1977 0.1977
Plasmodium falciparum tubulin delta chain, putative 0.0056 0.0759 0.1883
Brugia malayi Carboxylesterase family protein 0.0012 0.0025 0.0043
Loa Loa (eye worm) hypothetical protein 0.0027 0.0286 0.0449
Schistosoma mansoni twik family of potassium channels-related 0.0019 0.0144 0.0144
Echinococcus granulosus ubiquitin conjugating enzyme E2 N 0.0026 0.0264 0.0264
Entamoeba histolytica hypothetical protein 0.0034 0.0402 0.0962
Trichomonas vaginalis tubulin gamma chain, putative 0.0128 0.1977 0.503
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0047 0.0613 0.1051
Loa Loa (eye worm) hypothetical protein 0.0019 0.0144 0.0226
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0106 0.1607 0.1607
Trypanosoma cruzi beta tubulin, putative 0.0243 0.3904 1
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.009 0.133 0.133
Loa Loa (eye worm) hypothetical protein 0.002 0.0165 0.0259
Leishmania major beta tubulin 0.0243 0.3904 1
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0016 0.0088 0.0088
Loa Loa (eye worm) tubulin beta chain 0.0243 0.3904 0.6131
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0.0088 0.015
Trypanosoma brucei alpha tubulin, putative 0.0073 0.1042 0.2614
Trichomonas vaginalis inositol monophosphatase, putative 0.0023 0.0218 0.0497
Echinococcus multilocularis carboxylesterase 5A 0.0071 0.1011 0.1011
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0017 0.0104 0.0122
Echinococcus granulosus bloom syndrome protein 0.0019 0.0139 0.0139
Trypanosoma cruzi cytochrome P450, putative 0.0033 0.0374 0.075

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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