Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | acetyl-CoA carboxylase beta | Starlite/ChEMBL | No references |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | peroxidasin | 0.0354 | 1 | 1 |
Schistosoma mansoni | peroxidasin | 0.0354 | 1 | 1 |
Toxoplasma gondii | acetyl-CoA carboxylase ACC1 | 0.0101 | 0.2311 | 1 |
Mycobacterium ulcerans | acetyl-/propionyl-coenzyme a carboxylase alpha chain, AccA2 | 0.0039 | 0.0402 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0354 | 1 | 1 |
Toxoplasma gondii | acetyl-coA carboxylase ACC2 | 0.0101 | 0.2311 | 1 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0354 | 1 | 1 |
Onchocerca volvulus | 0.0354 | 1 | 0.5 | |
Onchocerca volvulus | Peroxidase homolog | 0.0354 | 1 | 0.5 |
Plasmodium falciparum | biotin carboxylase subunit of acetyl CoA carboxylase, putative | 0.0073 | 0.1459 | 0.5 |
Onchocerca volvulus | Peroxidasin homolog | 0.0354 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0354 | 1 | 1 |
Trypanosoma brucei | 3-methylcrotonyl-CoA carboxylase alpha subunit, putative | 0.0039 | 0.0402 | 0.1741 |
Onchocerca volvulus | 0.0354 | 1 | 0.5 | |
Onchocerca volvulus | Peroxidasin homolog | 0.0354 | 1 | 0.5 |
Onchocerca volvulus | Peroxidase homolog | 0.0354 | 1 | 0.5 |
Mycobacterium tuberculosis | Probable acetyl-/propionyl-coenzyme A carboxylase alpha chain (alpha subunit) AccA2: biotin carboxylase + biotin carboxyl carrie | 0.0039 | 0.0402 | 0.5 |
Mycobacterium leprae | Probable bifunctional protein acetyl-/propionyl-coenzyme A carboxylase, alpha chain AccA3 (BccP) | 0.0039 | 0.0402 | 0.5 |
Brugia malayi | Peroxidasin | 0.0354 | 1 | 1 |
Onchocerca volvulus | Chorion peroxidase homolog | 0.0354 | 1 | 0.5 |
Trypanosoma cruzi | acetyl-CoA carboxylase | 0.0063 | 0.1137 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0354 | 1 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.0354 | 1 | 1 |
Brugia malayi | Blistered cuticle protein 3 | 0.0354 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0354 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0354 | 1 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.0354 | 1 | 1 |
Trypanosoma brucei | 3-methylcrotonyl-CoA carboxylase alpha subunit, putative | 0.0039 | 0.0402 | 0.1741 |
Leishmania major | acetyl-CoA carboxylase, putative | 0.0101 | 0.2311 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0354 | 1 | 1 |
Mycobacterium tuberculosis | Probable pyruvate carboxylase Pca (pyruvic carboxylase) | 0.0039 | 0.0402 | 0.5 |
Mycobacterium ulcerans | acetyl-/propionyl-coenzyme a carboxylase alpha chain AccA1 | 0.0039 | 0.0402 | 0.5 |
Trypanosoma brucei | acetyl-CoA carboxylase | 0.0101 | 0.2311 | 1 |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.0354 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0354 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0354 | 1 | 1 |
Schistosoma mansoni | peroxidasin | 0.0354 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0354 | 1 | 1 |
Mycobacterium ulcerans | pyruvate carboxylase | 0.0039 | 0.0402 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0354 | 1 | 1 |
Onchocerca volvulus | Dual oxidase homolog | 0.0354 | 1 | 0.5 |
Wolbachia endosymbiont of Brugia malayi | Acetyl/propionyl-CoA carboxylase, alpha subunit | 0.0039 | 0.0402 | 0.5 |
Echinococcus granulosus | peroxidasin | 0.0354 | 1 | 1 |
Echinococcus multilocularis | acetyl coenzyme A carboxylase 1 | 0.0101 | 0.2311 | 0.1989 |
Loa Loa (eye worm) | hypothetical protein | 0.0354 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0354 | 1 | 1 |
Plasmodium vivax | biotin carboxylase subunit of acetyl CoA carboxylase, putative | 0.0073 | 0.1459 | 0.5 |
Echinococcus granulosus | acetyl coenzyme A carboxylase 1 | 0.0101 | 0.2311 | 0.1989 |
Schistosoma mansoni | acetyl-CoA carboxylase | 0.0101 | 0.2311 | 0.1989 |
Chlamydia trachomatis | biotin carboxylase | 0.0035 | 0.0294 | 0.5 |
Brugia malayi | Animal haem peroxidase family protein | 0.0354 | 1 | 1 |
Mycobacterium ulcerans | bifunctional protein acetyl-/propionyl-coenzyme a carboxylase (alpha chain) AccA3 | 0.0039 | 0.0402 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0354 | 1 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.0354 | 1 | 1 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0354 | 1 | 1 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0354 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0354 | 1 | 1 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0354 | 1 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.0354 | 1 | 1 |
Onchocerca volvulus | 0.0354 | 1 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.