Detailed information for compound 1966116

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 417.369 | Formula: C19H19N3O8
  • H donors: 4 H acceptors: 6 LogP: 0.37 Rotable bonds: 12
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(N[C@H](C(=O)O)CC(=O)O)CCc1ccc(o1)C(=O)Oc1ccc(cc1)C(=N)N
  • InChi: 1S/C19H19N3O8/c20-17(21)10-1-3-12(4-2-10)30-19(28)14-7-5-11(29-14)6-8-15(23)22-13(18(26)27)9-16(24)25/h1-5,7,13H,6,8-9H2,(H3,20,21)(H,22,23)(H,24,25)(H,26,27)/t13-/m0/s1
  • InChiKey: OJLOAPPEYJCQFX-ZDUSSCGKSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens protease, serine, 1 (trypsin 1) Starlite/ChEMBL No references
Homo sapiens transmembrane protease, serine 15 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Onchocerca volvulus Get druggable targets OG5_126639 All targets in OG5_126639
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) Get druggable targets OG5_126639 All targets in OG5_126639
Schistosoma japonicum ko:K09639 transmembrane protease, serine 8, putative Get druggable targets OG5_126639 All targets in OG5_126639
Brugia malayi Trypsin family protein Get druggable targets OG5_126639 All targets in OG5_126639
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126639 All targets in OG5_126639
Schistosoma japonicum ko:K09639 transmembrane protease, serine 8, putative Get druggable targets OG5_126639 All targets in OG5_126639
Onchocerca volvulus Get druggable targets OG5_126639 All targets in OG5_126639
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126639 All targets in OG5_126639
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) Get druggable targets OG5_126639 All targets in OG5_126639
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi Trypsin family protein protease, serine, 1 (trypsin 1) 247 aa 287 aa 21.6 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Toxoplasma gondii histone deacetylase HDAC4 0.0156 0.172 0.2998
Schistosoma mansoni cercarial elastase (S01 family) 0.001 0.0049 0.0049
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0012 0.0072 0.0186
Mycobacterium leprae putative cytochrome p450 0.0012 0.0072 0.046
Schistosoma mansoni voltage-gated potassium channel 0.0006 0.0009 0.0009
Brugia malayi hypothetical protein 0.0162 0.1783 0.1778
Brugia malayi intermediate filament protein 0.0048 0.0492 0.0485
Echinococcus granulosus transient receptor potential gamma protein 0.0006 0.0009 0.0009
Loa Loa (eye worm) Smad1 0.0007 0.0015 0.0008
Echinococcus multilocularis hyperpolarization activated cyclic 0.0006 0.0009 0.0009
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0012 0.0072 0.0148
Loa Loa (eye worm) carboxylesterase 0.0882 1 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0008 0.0032 0.0032
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0116 0.1262 0.1262
Echinococcus granulosus nuclear receptor co repressor related ncor 0.0146 0.1608 0.1608
Schistosoma mansoni amine GPCR 0.0008 0.0032 0.0032
Echinococcus granulosus caspase 0.0124 0.1349 0.1349
Echinococcus granulosus transient receptor potential cation channel 0.0006 0.0012 0.0012
Loa Loa (eye worm) CYP4Cod1 0.0021 0.0178 0.0171
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0175 0.1941 0.1935
Echinococcus granulosus histone deacetylase 6 0.0291 0.3261 0.3261
Echinococcus granulosus rhodopsin orphan GPCR 0.0008 0.0032 0.0032
Schistosoma mansoni transient receptor potential channel 0.0006 0.0009 0.0009
Echinococcus multilocularis two pore calcium channel protein 2 0.0006 0.0009 0.0009
Onchocerca volvulus 0.0008 0.0032 0.0148
Schistosoma mansoni histone deacetylase 0.0507 0.5721 0.5721
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0006 0.0009 0.0009
Loa Loa (eye worm) RNA binding protein 0.005 0.051 0.0504
Echinococcus multilocularis rhodopsin orphan GPCR 0.0008 0.0032 0.0032
Echinococcus granulosus neuropeptide s receptor 0.0321 0.3596 0.3596
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0047 0.0473 0.0816
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0048 0.0492 0.0485
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0008 0.0032 0.0025
Toxoplasma gondii transporter, cation channel family protein 0.0006 0.0009 0.0005
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0012 0.0072 0.011
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0008 0.0032 0.0032
Echinococcus granulosus BC026374 protein S09 family 0.0149 0.164 0.164
Onchocerca volvulus 0.0008 0.0032 0.0148
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0012 0.0072 0.0186
Schistosoma mansoni ap endonuclease 0.0014 0.0098 0.0098
Toxoplasma gondii hypothetical protein 0.0006 0.0009 0.0005
Trypanosoma cruzi histone deacetylase, putative 0.0156 0.172 0.2995
Echinococcus granulosus rhodopsin orphan GPCR 0.0008 0.0032 0.0032
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0006 0.0009 0.0009
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0012 0.0072 0.0148
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0025
Echinococcus multilocularis lamin 0.0048 0.0492 0.0492
Toxoplasma gondii cytochrome p450 superfamily protein 0.0012 0.0072 0.0115
Echinococcus granulosus glycoprotein Antigen 5 0.001 0.0049 0.0049
Trypanosoma cruzi histone deacetylase, putative 0.0156 0.172 0.2995
Schistosoma mansoni cercarial elastase (S01 family) 0.001 0.0049 0.0049
Mycobacterium ulcerans hypothetical protein 0.0036 0.0346 0.1868
Brugia malayi TAR-binding protein 0.005 0.051 0.0504
Trichomonas vaginalis glucosylceramidase, putative 0.0175 0.1941 0.3385
Loa Loa (eye worm) hypothetical protein 0.0006 0.0009 0.0003
Schistosoma mansoni hypothetical protein 0.0006 0.0007 0.0007
Echinococcus multilocularis glycoprotein Antigen 5 0.001 0.0049 0.0049
Echinococcus multilocularis two pore calcium channel protein 1 0.0006 0.0009 0.0009
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0006 0.0009 0.0009
Trypanosoma brucei histone deacetylase 3 0.0291 0.3261 0.5693
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0006 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0025
Echinococcus multilocularis g protein coupled receptor 0.0008 0.0032 0.0032
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0008 0.0032 0.0032
Echinococcus multilocularis sodium channel protein 0.0006 0.0009 0.0009
Echinococcus multilocularis neuropeptide receptor 0.0008 0.0032 0.0032
Echinococcus multilocularis transient receptor potential cation channel 0.0006 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0025
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0008 0.0032 0.0032
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.001 0.0059 0.0104
Echinococcus granulosus tm gpcr rhodopsin 0.0008 0.0032 0.0032
Toxoplasma gondii histone deacetylase HDAC2 0.0507 0.5721 1
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.001 0.0049 0.0049
Echinococcus multilocularis dro:myosuppressin receptor 0.0008 0.0032 0.0032
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0008 0.0032 0.0032
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0012 0.0072 0.0186
Loa Loa (eye worm) hypothetical protein 0.0006 0.0012 0.0006
Mycobacterium ulcerans acyl-CoA synthetase 0.001 0.0059 0.0065
Echinococcus multilocularis transient receptor potential cation channel 0.0006 0.0012 0.0012
Echinococcus granulosus acetylcholinesterase 0.0882 1 1
Trypanosoma cruzi cytochrome P450, putative 0.0021 0.0178 0.0295
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0006 0.0009 0.0009
Schistosoma mansoni cercarial elastase (S01 family) 0.001 0.0049 0.0049
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0008 0.0032 0.0032
Trypanosoma brucei histone deacetylase 2 0.0156 0.172 0.2995
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0012 0.0072 0.011
Schistosoma mansoni hypothetical protein 0.0008 0.0032 0.0032
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0006 0.0009 0.0005
Onchocerca volvulus 0.001 0.0059 0.0306
Schistosoma mansoni smad1 5 8 and 0.0007 0.0015 0.0015
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0006 0.0009 0.0009
Echinococcus multilocularis histone deacetylase 0.0291 0.3261 0.3261
Echinococcus multilocularis histone deacetylase 7 0.0291 0.3261 0.3261
Loa Loa (eye worm) hypothetical protein 0.0044 0.0436 0.043
Echinococcus granulosus potassium voltage gated channel protein 0.0006 0.0009 0.0009
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0006 0.0009 0.0003
Brugia malayi hypothetical protein 0.0008 0.0032 0.0025
Brugia malayi Carboxylesterase family protein 0.0149 0.164 0.1634
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0014 0.0098 0.5
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0012 0.0072 0.0186
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0047 0.0473 0.0816
Echinococcus multilocularis caspase 8 0.0047 0.0473 0.0473
Echinococcus multilocularis musashi 0.0048 0.0492 0.0492
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0006 0.0009 0.0009
Onchocerca volvulus 0.0106 0.1153 0.6693
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0008 0.0032 0.0025
Brugia malayi Carboxylesterase family protein 0.0149 0.164 0.1634
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0047 0.0473 0.0473
Loa Loa (eye worm) hypothetical protein 0.0036 0.0346 0.0339
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0025
Echinococcus multilocularis caspase 3 0.0077 0.0816 0.0816
Schistosoma mansoni neuroligin 3 (S09 family) 0.0149 0.164 0.164
Trypanosoma cruzi cytochrome P450, putative 0.0021 0.0178 0.0295
Brugia malayi acetyl-Coenzyme A synthetase 2 0.001 0.0059 0.0052
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0008 0.0032 0.0148
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0012 0.0072 0.0148
Giardia lamblia Histone deacetylase 0.0507 0.5721 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0008 0.0032 0.0032
Trypanosoma cruzi metacaspase 5, putative 0.0047 0.0473 0.0812
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0008 0.0032 0.0032
Onchocerca volvulus 0.0008 0.0032 0.0148
Echinococcus granulosus sex peptide receptor 0.0008 0.0032 0.0032
Brugia malayi MH2 domain containing protein 0.0007 0.0015 0.0008
Toxoplasma gondii histone deacetylase HDAC1 0.0291 0.3261 0.5695
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0014 0.0098 0.0098
Echinococcus granulosus neuropeptide receptor A26 0.0321 0.3596 0.3596
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0008 0.0032 0.0032
Onchocerca volvulus 0.0019 0.0162 0.0904
Leishmania major histone deacetylase, putative 0.0507 0.5721 1
Echinococcus granulosus mothers against decapentaplegic 5 0.0007 0.0015 0.0015
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0012 0.0072 0.0148
Echinococcus multilocularis voltage dependent calcium channel 0.0006 0.0009 0.0009
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0012 0.0072 0.0186
Mycobacterium ulcerans acyl-CoA synthetase 0.001 0.0059 0.0065
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0014 0.0098 0.0155
Leishmania major acetyl-CoA synthetase, putative 0.001 0.0059 0.0087
Toxoplasma gondii propionate-CoA ligase 0.001 0.0059 0.0092
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0006 0.0009 0.0009
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0175 0.1941 0.1935
Loa Loa (eye worm) TAR-binding protein 0.005 0.051 0.0504
Echinococcus multilocularis transient receptor potential cation channel 0.0006 0.0009 0.0009
Echinococcus multilocularis orexin receptor type 2 0.0008 0.0032 0.0032
Brugia malayi histone deacetylase 1 (HD1) 0.0507 0.5721 0.5718
Echinococcus granulosus somatostatin receptor 0.0008 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0025
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0006 0.0009 0.0003
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0012 0.0072 0.0186
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0008 0.0032 0.0025
Brugia malayi hypothetical protein 0.0006 0.0009 0.0003
Schistosoma mansoni smad1 5 8 and 0.0007 0.0015 0.0015
Onchocerca volvulus 0.0008 0.0032 0.0148
Brugia malayi hypothetical protein 0.0008 0.0032 0.0025
Echinococcus granulosus biogenic amine 5HT receptor 0.0008 0.0032 0.0032
Mycobacterium ulcerans acyl-CoA synthetase 0.001 0.0059 0.0065
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0025
Onchocerca volvulus 0.0008 0.0032 0.0148
Brugia malayi Cytochrome P450 family protein 0.0012 0.0072 0.0066
Echinococcus multilocularis neuropeptide receptor 0.0008 0.0032 0.0032
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.001 0.0059 0.0104
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0025
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0006 0.0009 0.0003
Schistosoma mansoni 60S ribosomal protein L21 0.0006 0.0009 0.0009
Echinococcus multilocularis 0.0012 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0025
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0013 0.0087 0.0087
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0014 0.0098 0.0348
Plasmodium vivax histone deacetylase 2, putative 0.0291 0.3261 0.5695
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0006 0.0009 0.0009
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0006 0.0009 0.0009
Echinococcus granulosus potassium voltage gated channel protein 0.0006 0.0009 0.0009
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0008 0.0032 0.0032
Loa Loa (eye worm) AMP-binding enzyme family protein 0.001 0.0059 0.0052
Schistosoma mansoni histone deacetylase hda2 0.0294 0.3298 0.3298
Echinococcus granulosus neuropeptides capa receptor 0.0008 0.0032 0.0032
Echinococcus multilocularis SWI:SNF matrix associated 0.0006 0.0007 0.0007
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0006 0.0009 0.0009
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0006 0.0009 0.0005
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0149 0.164 0.164
Echinococcus granulosus biogenic amine 5HT receptor 0.0008 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0025
Brugia malayi hypothetical protein 0.0149 0.164 0.1634
Schistosoma mansoni voltage-gated potassium channel 0.0006 0.0009 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0473 0.0816
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.001 0.0059 0.0065
Loa Loa (eye worm) hypothetical protein 0.0018 0.0146 0.0139
Brugia malayi hypothetical protein 0.0008 0.0032 0.0025
Echinococcus granulosus dro:myosuppressin receptor 0.0008 0.0032 0.0032
Trypanosoma brucei cytochrome P450, putative 0.0021 0.0178 0.0295
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0006 0.0009 0.0009
Trichomonas vaginalis glucosylceramidase, putative 0.0175 0.1941 0.3385
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0025
Echinococcus granulosus rhodopsin orphan GPCR 0.0008 0.0032 0.0032
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0006 0.0009 0.0009
Leishmania major histone deacetylase, putative 0.0507 0.5721 1
Echinococcus granulosus transient receptor potential cation channel 0.0006 0.0009 0.0009
Brugia malayi putative neuropeptide receptor 0.0008 0.0032 0.0025
Schistosoma mansoni ryanodine receptor related 0.0006 0.0009 0.0009
Schistosoma mansoni histone deacetylase 4 5 0.0291 0.3261 0.3261
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0006 0.0009 0.0009
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0047 0.0473 0.0816
Schistosoma mansoni transient receptor potential channel 4 0.0006 0.0009 0.0009
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0008 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0006 0.0009 0.0003
Schistosoma mansoni growth hormone secretagogue receptor 0.0008 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0019 0.0162 0.0155
Loa Loa (eye worm) hypothetical protein 0.0006 0.0009 0.0003
Echinococcus multilocularis acetylcholinesterase 0.0882 1 1
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.001 0.0049 0.0049
Schistosoma mansoni adenoreceptor 0.0008 0.0032 0.0032
Echinococcus granulosus TRP transient receptor potential channel 0.0006 0.0009 0.0009
Onchocerca volvulus 0.0149 0.164 0.9532
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0149 0.164 0.164
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0064 0.0672 0.0672
Loa Loa (eye worm) hypothetical protein 0.001 0.0049 0.0042
Trypanosoma cruzi histone deacetylase, putative 0.0291 0.3261 0.5693
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0006 0.0009 0.0009
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0008 0.0032 0.0032
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.001 0.0059 0.0087
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0047 0.0473 0.0816
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0014 0.0098 0.0069
Trichomonas vaginalis antibiotic synthetase, putative 0.001 0.0059 0.0092
Trichomonas vaginalis glucosylceramidase, putative 0.0175 0.1941 0.3385
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0006 0.0009 0.0009
Brugia malayi Trypsin family protein 0.001 0.0049 0.0042
Brugia malayi SEA domain containing protein 0.0018 0.0146 0.0139
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0025
Loa Loa (eye worm) hypothetical protein 0.0006 0.0009 0.0003
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0012 0.0072 0.0186
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0025
Trichomonas vaginalis histone deacetylase, putative 0.0507 0.5721 1
Onchocerca volvulus 0.0018 0.0146 0.0813
Loa Loa (eye worm) TK/ALK protein kinase 0.0019 0.0162 0.0155
Loa Loa (eye worm) hypothetical protein 0.0027 0.0243 0.0237
Echinococcus granulosus caspase 2 0.009 0.0969 0.0969
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0006 0.0009 0.0009
Brugia malayi Dopamine receptor protein 1 0.0008 0.0032 0.0025
Schistosoma mansoni voltage-gated potassium channel 0.0006 0.0009 0.0009
Schistosoma mansoni alpha-1 adrenergic receptor 0.0008 0.0032 0.0032
Schistosoma mansoni cercarial elastase (S01 family) 0.001 0.0049 0.0049
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0023 0.0206 0.0206
Echinococcus multilocularis neuropeptides capa receptor 0.0008 0.0032 0.0032
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0006 0.0009 0.0009
Loa Loa (eye worm) neuropeptide F receptor 0.0008 0.0032 0.0025
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0008 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.009 0.0969 0.0963
Brugia malayi MH1 domain containing protein 0.0007 0.0015 0.0008
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0047 0.0473 0.0466
Schistosoma mansoni ap endonuclease 0.0014 0.0098 0.0098
Schistosoma mansoni voltage-gated potassium channel 0.0006 0.0009 0.0009
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.001 0.0059 0.0065
Schistosoma mansoni voltage-gated potassium channel 0.0006 0.0009 0.0009
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0012 0.0072 0.0186
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0006 0.0009 0.0009
Echinococcus granulosus potassium large conductance calcium activated 0.0006 0.0009 0.0009
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0006 0.0009 0.0003
Echinococcus granulosus enteropeptidase 0.001 0.0049 0.0049
Brugia malayi G-protein coupled receptor 0.0008 0.0032 0.0025
Echinococcus multilocularis histone deacetylase 6 0.0294 0.3298 0.3298
Echinococcus granulosus SWI:SNF matrix associated 0.0006 0.0007 0.0007
Schistosoma mansoni cercarial elastase (S01 family) 0.001 0.0049 0.0049
Leishmania major cytochrome p450-like protein 0.0012 0.0072 0.011
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0025
Schistosoma mansoni vesicular amine transporter 0.0006 0.0009 0.0009
Echinococcus granulosus potassium voltage gated channel protein 0.0006 0.0009 0.0009
Onchocerca volvulus 0.0044 0.0436 0.2507
Onchocerca volvulus 0.0116 0.1262 0.7328
Mycobacterium ulcerans acyl-CoA synthetase 0.001 0.0059 0.0065
Echinococcus granulosus MAM 0.0019 0.0162 0.0162
Loa Loa (eye worm) hypothetical protein 0.0006 0.0009 0.0003
Brugia malayi putative neuropeptide receptor NPR1 0.0008 0.0032 0.0025
Schistosoma mansoni hypothetical protein 0.0302 0.338 0.338
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0025
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.001 0.0059 0.0065
Schistosoma mansoni transient receptor potential channel 0.0006 0.0009 0.0009
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0006 0.0009 0.0009
Echinococcus granulosus voltage gated potassium channel 0.0006 0.0009 0.0009
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0008 0.0032 0.0032
Echinococcus granulosus short transient receptor potential channel 6 0.0006 0.0009 0.0009
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0006 0.0009 0.0009
Treponema pallidum exodeoxyribonuclease (exoA) 0.0014 0.0098 0.5
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.001 0.0059 0.0065
Echinococcus granulosus carboxylesterase 5A 0.0882 1 1
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0025
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0047 0.0473 0.0816
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0507 0.5721 1
Echinococcus multilocularis neuroligin 0.0149 0.164 0.164
Brugia malayi ion channel NompC 0.0006 0.0009 0.0003
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0012 0.0072 0.0148
Echinococcus granulosus transmembrane protease serine 3 0.001 0.0049 0.0049
Echinococcus granulosus rhodopsin orphan GPCR 0.0008 0.0032 0.0032
Schistosoma mansoni two-pore calcium channel 0.0006 0.0009 0.0009
Loa Loa (eye worm) cytochrome P450 family protein 0.0012 0.0072 0.0066
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.001 0.0049 0.0049
Onchocerca volvulus 0.0149 0.164 0.9532
Brugia malayi MH2 domain containing protein 0.0096 0.104 0.1034
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.001 0.0059 0.0104
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0014 0.0098 0.0098
Echinococcus granulosus tm gpcr rhodopsin 0.0008 0.0032 0.0032
Echinococcus granulosus serotonin receptor 0.0008 0.0032 0.0032
Entamoeba histolytica acyl-CoA synthetase, putative 0.0036 0.0346 0.0507
Echinococcus granulosus cpg binding protein 0.0022 0.0195 0.0195
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0008 0.0032 0.0032
Brugia malayi sulfakinin receptor protein 0.0162 0.1783 0.1778
Brugia malayi Carboxylesterase family protein 0.0149 0.164 0.1634
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0006 0.0009 0.0009
Schistosoma mansoni voltage-gated potassium channel 0.0006 0.0009 0.0009
Echinococcus multilocularis rhodopsin orphan GPCR 0.0008 0.0032 0.0032
Echinococcus multilocularis SWI:SNF matrix associated 0.0006 0.0007 0.0007
Echinococcus multilocularis nuclear receptor co repressor related (ncor) 0.0146 0.1608 0.1608
Schistosoma mansoni biogenic amine receptor 0.0008 0.0032 0.0032
Echinococcus granulosus histone deacetylase 1 0.0507 0.5721 0.5721
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0006 0.0009 0.0009
Schistosoma mansoni tar DNA-binding protein 0.005 0.051 0.051
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0149 0.164 0.164
Brugia malayi MH2 domain containing protein 0.0007 0.0015 0.0008
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0025 0.0227 0.1153
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0006 0.0009 0.0003
Loa Loa (eye worm) transcription factor SMAD2 0.0096 0.104 0.1034
Loa Loa (eye worm) hypothetical protein 0.0116 0.1262 0.1256
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0064 0.0672 0.1159
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0006 0.0009 0.0015
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0025
Echinococcus granulosus two pore calcium channel protein 2 0.0006 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0025
Echinococcus granulosus hyperpolarization activated cyclic 0.0006 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0019 0.0162 0.0155
Loa Loa (eye worm) cytochrome P450 family protein 0.0021 0.0178 0.0171
Echinococcus multilocularis histone deacetylase 6 0.0291 0.3261 0.3261
Trichomonas vaginalis histone deacetylase, putative 0.0507 0.5721 1
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0149 0.164 0.164
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0027 0.0243 0.1257
Echinococcus multilocularis sodium leak channel non selective protein 0.0006 0.0009 0.0009
Trichomonas vaginalis glucosylceramidase, putative 0.0115 0.1253 0.2181
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0008 0.0032 0.0032
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.001 0.0059 0.0104
Echinococcus granulosus voltage gated potassium channel 0.0006 0.0009 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0473 0.0816
Echinococcus granulosus neuropeptide Y receptor 0.0008 0.0032 0.0032
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0008 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0006 0.0009 0.0003
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0036 0.0346 0.1868
Mycobacterium ulcerans acetyl-CoA synthetase 0.001 0.0059 0.0065
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.001 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0006 0.0009 0.0003
Echinococcus granulosus caspase 3 0.0077 0.0816 0.0816
Loa Loa (eye worm) hypothetical protein 0.0006 0.0009 0.0003
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0008 0.0032 0.0032
Loa Loa (eye worm) MH2 domain-containing protein 0.0007 0.0015 0.0008
Leishmania major acetyl-CoA synthetase, putative 0.001 0.0059 0.0087
Loa Loa (eye worm) hypothetical protein 0.0149 0.164 0.1634
Onchocerca volvulus Histone deacetylase 10 homolog 0.0156 0.172 1
Schistosoma mansoni neuropeptide receptor 0.0008 0.0032 0.0032
Echinococcus granulosus rhodopsin orphan GPCR 0.0008 0.0032 0.0032
Loa Loa (eye worm) calcium channel 0.0006 0.0009 0.0003
Toxoplasma gondii exonuclease III APE 0.0014 0.0098 0.016
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0473 0.0816
Brugia malayi ORL1-like opioid receptor 0.0008 0.0032 0.0025
Echinococcus multilocularis neuropeptide Y receptor 0.0008 0.0032 0.0032
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0672 0.3914
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.001 0.0059 0.0104
Brugia malayi Trypsin-like protease protein 5 0.001 0.0049 0.0042
Mycobacterium leprae Conserved hypothetical protein 0.0012 0.0072 0.046
Brugia malayi Serotonin receptor 0.0008 0.0032 0.0025
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0006 0.0009 0.0009
Schistosoma mansoni cercarial elastase (S01 family) 0.001 0.0049 0.0049
Echinococcus multilocularis Mastin 0.001 0.0049 0.0049
Echinococcus multilocularis transient receptor potential cation channel 0.0006 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0025
Schistosoma mansoni lamin 0.0048 0.0492 0.0492
Schistosoma mansoni voltage-gated potassium channel 0.0006 0.0009 0.0009
Echinococcus granulosus Smad4 0.0007 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0006 0.0009 0.0003
Echinococcus granulosus calcium activated potassium channel 0.0006 0.0009 0.0009
Schistosoma mansoni tar DNA-binding protein 0.005 0.051 0.051
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.001 0.0049 0.0049
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0064 0.0672 0.3938
Echinococcus granulosus transient receptor potential cation channel 0.0006 0.0009 0.0009
Brugia malayi cytochrome P450 0.0012 0.0072 0.0066
Loa Loa (eye worm) hypothetical protein 0.0027 0.0243 0.0237
Echinococcus multilocularis allatostatin A receptor 0.0008 0.0032 0.0032
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0006 0.0009 0.0003
Trypanosoma cruzi metacaspase, putative 0.0047 0.0473 0.0812
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0006 0.0009 0.0009
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0014 0.0098 0.0155
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.001 0.0049 0.0042
Brugia malayi hypothetical protein 0.0008 0.0032 0.0025
Onchocerca volvulus 0.0008 0.0032 0.0148
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0006 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0007 0.0016 0.0009
Leishmania major histone deacetylase, putative 0.0291 0.3261 0.5693
Echinococcus multilocularis lamin dm0 0.0048 0.0492 0.0492
Loa Loa (eye worm) hypothetical protein 0.0006 0.0009 0.0003
Echinococcus multilocularis transfer RNA-Gly 0.0006 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0149 0.164 0.1634
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0012 0.0072 0.0148
Loa Loa (eye worm) hypothetical protein 0.0006 0.0009 0.0003
Echinococcus multilocularis histone deacetylase 8 0.0156 0.172 0.172
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0008 0.0032 0.0032
Brugia malayi neuropeptide F receptor 0.0008 0.0032 0.0025
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0006 0.0009 0.0015
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.001 0.0059 0.0092
Plasmodium falciparum acyl-CoA synthetase 0.0027 0.0243 0.0414
Brugia malayi G protein-coupled receptor 0.0008 0.0032 0.0025
Echinococcus multilocularis fmrfamide receptor 0.0008 0.0032 0.0032
Echinococcus granulosus neuropeptide FF receptor 2 0.0008 0.0032 0.0032
Brugia malayi AMP-binding enzyme family protein 0.001 0.0059 0.0052
Trypanosoma brucei metacaspase MCA3 0.0047 0.0473 0.0812
Onchocerca volvulus 0.0021 0.0182 0.102
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0006 0.0009 0.0003
Echinococcus multilocularis neuropeptide FF receptor 2 0.0008 0.0032 0.0032
Brugia malayi Cytochrome P450 family protein 0.0021 0.0178 0.0171
Brugia malayi Trypsin family protein 0.001 0.0049 0.0042
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0025 0.0227 0.1153
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0124 0.1349 0.1349
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.001 0.0059 0.0065
Loa Loa (eye worm) acetylcholinesterase 1 0.0882 1 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0008 0.0032 0.0032
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0006 0.0009 0.0009
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0012 0.0072 0.0148
Loa Loa (eye worm) hypothetical protein 0.0027 0.0243 0.0237
Echinococcus multilocularis caspase 2 0.009 0.0969 0.0969
Schistosoma mansoni voltage-gated potassium channel 0.0006 0.0009 0.0009
Schistosoma mansoni voltage-gated potassium channel 0.0006 0.0009 0.0009
Onchocerca volvulus 0.0048 0.0492 0.283
Echinococcus multilocularis histone deacetylase 1 0.0507 0.5721 0.5721
Brugia malayi Smad1 0.0007 0.0015 0.0008
Trypanosoma brucei histone deacetylase, putative 0.0291 0.3261 0.5693
Loa Loa (eye worm) hypothetical protein 0.0007 0.0016 0.0009
Loa Loa (eye worm) hypothetical protein 0.0006 0.0009 0.0003
Echinococcus multilocularis histone deacetylase 3 0.0507 0.5721 0.5721
Brugia malayi voltage-dependent calcium channel 0.0006 0.0009 0.0003
Toxoplasma gondii histone lysine methyltransferase SET1 0.004 0.0398 0.0684
Loa Loa (eye worm) hypothetical protein 0.0006 0.0009 0.0003
Loa Loa (eye worm) hypothetical protein 0.0006 0.0009 0.0003
Schistosoma mansoni voltage-gated potassium channel 0.0006 0.0009 0.0009
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0006 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.001 0.0049 0.0042
Echinococcus multilocularis potassium voltage gated channel protein 0.0006 0.0009 0.0009
Echinococcus multilocularis transient receptor potential gamma protein 0.0006 0.0009 0.0009
Schistosoma mansoni histone deacetylase hda2 0.0156 0.172 0.172
Echinococcus multilocularis para nitrobenzyl esterase 0.0149 0.164 0.164
Echinococcus granulosus ryanodine receptor 44f 0.0006 0.0009 0.0009
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0006 0.0009 0.0009
Echinococcus multilocularis potassium large conductance calcium activated 0.0006 0.0009 0.0009
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0006 0.0009 0.0005
Loa Loa (eye worm) hypothetical protein 0.0006 0.0009 0.0003
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0012 0.0072 0.0148
Echinococcus granulosus transient receptor potential cation channel 0.0006 0.0009 0.0009
Echinococcus multilocularis voltage gated potassium channel 0.0006 0.0009 0.0009
Schistosoma mansoni hypothetical protein 0.0019 0.0162 0.0162
Onchocerca volvulus Neuropeptide F receptor homolog 0.0008 0.0032 0.0148
Echinococcus multilocularis g-protein coupled receptor 0.0008 0.0032 0.0032
Brugia malayi MH1 domain containing protein 0.0007 0.0015 0.0008
Onchocerca volvulus 0.001 0.0059 0.0306
Schistosoma mansoni hypothetical protein 0.0018 0.0146 0.0146
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0012 0.0072 0.0148
Brugia malayi RNA binding protein 0.005 0.051 0.0504
Plasmodium vivax histone deacetylase 1, putative 0.0507 0.5721 1
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0006 0.0009 0.0003
Echinococcus granulosus neuropeptide receptor 0.0008 0.0032 0.0032
Echinococcus multilocularis transmembrane protease serine 3 0.001 0.0049 0.0049
Schistosoma mansoni voltage-gated potassium channel 0.0006 0.0009 0.0009
Echinococcus granulosus lamin dm0 0.0048 0.0492 0.0492
Echinococcus granulosus g-protein coupled receptor 0.0008 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0138 0.1518 0.1512
Loa Loa (eye worm) ion channel NompC 0.0006 0.0009 0.0003
Leishmania major 4-coumarate:coa ligase-like protein 0.0036 0.0346 0.0589
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0008 0.0032 0.0032
Mycobacterium ulcerans acyl-CoA synthetase 0.001 0.0059 0.0065
Echinococcus granulosus g protein coupled receptor 0.0008 0.0032 0.0032
Brugia malayi RE15519p 0.0008 0.0032 0.0025
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0008 0.0032 0.0032
Plasmodium falciparum histone deacetylase 2 0.0291 0.3261 0.5695
Onchocerca volvulus 0.0018 0.0146 0.0813
Echinococcus granulosus intermediate filament protein 0.0048 0.0492 0.0492
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0012 0.0072 0.0186
Brugia malayi cation channel family protein 0.0006 0.0009 0.0003
Onchocerca volvulus 0.001 0.0059 0.0306
Echinococcus multilocularis potassium voltage gated channel protein 0.0006 0.0009 0.0009
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0027 0.0243 1
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0008 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0507 0.5721 0.5718
Echinococcus granulosus acetylcholinesterase 0.0882 1 1
Onchocerca volvulus 0.0008 0.0032 0.0148
Schistosoma mansoni cercarial elastase (S01 family) 0.001 0.0049 0.0049
Brugia malayi AKH receptor 0.0008 0.0032 0.0025
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0025
Loa Loa (eye worm) hypothetical protein 0.0047 0.0482 0.0475
Loa Loa (eye worm) hypothetical protein 0.0006 0.0009 0.0003
Brugia malayi Dopamine receptor protein 2 0.0008 0.0032 0.0025
Echinococcus multilocularis serotonin receptor 0.0008 0.0032 0.0032
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0007 0.0015 0.0015
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0006 0.0009 0.0003
Schistosoma mansoni voltage-gated potassium channel 0.0006 0.0009 0.0009
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0006 0.0009 0.0009
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0012 0.0072 0.0148
Loa Loa (eye worm) carboxylesterase 0.0149 0.164 0.1634
Schistosoma mansoni biogenic amine (5HT) receptor 0.0008 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0036 0.0346 0.0339
Brugia malayi F/Y-rich N-terminus family protein 0.0006 0.0014 0.0007
Trypanosoma cruzi metacaspase, putative 0.0047 0.0473 0.0812
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0006 0.0009 0.0003
Schistosoma mansoni cytochrome P450 0.0012 0.0072 0.0072
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0008 0.0032 0.0032
Trypanosoma brucei metacaspase 0.0047 0.0473 0.0812
Echinococcus multilocularis rhodopsin orphan GPCR 0.0008 0.0032 0.0032
Echinococcus multilocularis G protein coupled receptor 139 0.0008 0.0032 0.0032
Trypanosoma brucei metacaspase MCA2 0.0047 0.0473 0.0812
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0025
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0006 0.0009 0.0009
Schistosoma mansoni hypothetical protein 0.0044 0.0436 0.0436
Mycobacterium ulcerans carboxylesterase, LipT 0.0149 0.164 1
Schistosoma mansoni opsin-like receptor 0.0008 0.0032 0.0032
Schistosoma mansoni biogenic amine (5HT) receptor 0.0008 0.0032 0.0032
Trypanosoma brucei histone deacetylase 1 0.0507 0.5721 1
Echinococcus multilocularis transient receptor potential cation channel 0.0006 0.0009 0.0009
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.001 0.0059 0.0087
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0014 0.0098 0.016
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0036 0.0346 0.1899
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0006 0.0009 0.0009
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0008 0.0032 0.0032
Echinococcus multilocularis shaker cognate 0.0006 0.0009 0.0009
Schistosoma mansoni biogenic amine receptor 0.0008 0.0032 0.0032
Echinococcus granulosus apoptotic protease activating factor 1 0.0044 0.0436 0.0436
Entamoeba histolytica acyl-CoA synthetase, putative 0.0036 0.0346 0.0507
Echinococcus multilocularis neuropeptide receptor A26 0.0321 0.3596 0.3596
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.005 0.051 0.0504
Schistosoma mansoni voltage-gated potassium channel 0.0006 0.0009 0.0009
Brugia malayi G-protein coupled receptor 0.0008 0.0032 0.0025
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0008 0.0032 0.0032
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0006 0.0009 0.0003
Mycobacterium ulcerans acyl-CoA synthetase 0.001 0.0059 0.0065
Onchocerca volvulus Cell death protein 3 homolog 0.009 0.0969 0.5618
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.001 0.0059 0.0104
Brugia malayi Intermediate filament tail domain containing protein 0.0048 0.0492 0.0485
Onchocerca volvulus 0.0008 0.0032 0.0148
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0012 0.0072 0.0186
Schistosoma mansoni amine GPCR 0.0008 0.0032 0.0032
Echinococcus granulosus neuropeptide Y receptor 0.0008 0.0032 0.0032
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0008 0.0032 0.0032
Brugia malayi Protein kinase domain containing protein 0.0019 0.0162 0.0155
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.001 0.0059 0.0087
Schistosoma mansoni gliotactin 0.0149 0.164 0.164
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0006 0.0009 0.0009
Echinococcus granulosus hyperpolarization activated cyclic 0.0006 0.0009 0.0009
Echinococcus granulosus transient receptor potential cation channel 0.0006 0.0009 0.0009
Schistosoma mansoni cpg binding protein 0.0022 0.0195 0.0195
Loa Loa (eye worm) voltage-gated potassium channel 0.0006 0.0009 0.0003
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0008 0.0032 0.0032
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0006 0.0009 0.0009
Leishmania major cytochrome p450-like protein 0.0021 0.0178 0.0295
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0014 0.0098 0.016
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0047 0.0473 0.0816
Brugia malayi hypothetical protein 0.0008 0.0032 0.0025
Loa Loa (eye worm) AMP-binding enzyme family protein 0.001 0.0059 0.0052
Brugia malayi Histone deacetylase family protein 0.0291 0.3261 0.3256
Loa Loa (eye worm) histone deacetylase 1 0.0507 0.5721 0.5718
Onchocerca volvulus 0.0008 0.0032 0.0148
Loa Loa (eye worm) hypothetical protein 0.0047 0.0473 0.0466
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0006 0.0009 0.0009
Trichomonas vaginalis glucosylceramidase, putative 0.0175 0.1941 0.3385
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0008 0.0032 0.0025
Echinococcus multilocularis mothers against decapentaplegic 5 0.0007 0.0015 0.0015
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0047 0.0473 0.0816
Trichomonas vaginalis glucosylceramidase, putative 0.0175 0.1941 0.3385
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0027 0.0243 0.1223
Schistosoma mansoni neuropeptide F-like receptor 0.0008 0.0032 0.0032
Trypanosoma cruzi metacaspase, putative 0.0047 0.0473 0.0812
Echinococcus granulosus lamin 0.0048 0.0492 0.0492
Echinococcus multilocularis rhodopsin orphan GPCR 0.0008 0.0032 0.0032
Echinococcus granulosus cytochrome P450 2K1 0.0012 0.0072 0.0072
Schistosoma mansoni hypothetical protein 0.0008 0.0032 0.0032
Schistosoma mansoni hypothetical protein 0.0006 0.0009 0.0009
Echinococcus granulosus hypothetical protein 0.0006 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0135 0.1481 0.1475
Loa Loa (eye worm) histone deacetylase 0.0291 0.3261 0.3256
Echinococcus granulosus peptide allatostatin:somatostatin 0.0008 0.0032 0.0032
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0014 0.0098 0.0091
Echinococcus multilocularis potassium voltage gated channel protein 0.0006 0.0009 0.0009
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.001 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0022 0.0196 0.019
Brugia malayi AMP-binding enzyme family protein 0.0036 0.0346 0.0339
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0012 0.0072 0.0148
Schistosoma mansoni voltage-gated potassium channel 0.0006 0.0009 0.0009
Brugia malayi histone deacetylase 11 0.0156 0.172 0.1714
Brugia malayi Trypsin family protein 0.0116 0.1262 0.1256
Onchocerca volvulus 0.0008 0.0032 0.0148
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0006 0.0009 0.0009
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.001 0.0059 0.0104
Echinococcus multilocularis carboxylesterase 5A 0.0882 1 1
Schistosoma mansoni Smad4 0.0007 0.0015 0.0015
Plasmodium falciparum histone deacetylase, putative 0.0291 0.3261 0.5695
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0025
Trichomonas vaginalis glucosylceramidase, putative 0.0121 0.1323 0.2304
Plasmodium vivax acetyl-CoA synthetase, putative 0.001 0.0059 0.0092
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0123 0.1338 0.1338
Echinococcus granulosus dnaJ subfamily B 0.0302 0.338 0.338
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0672 0.3914
Echinococcus granulosus histone deacetylase 7 0.0291 0.3261 0.3261
Loa Loa (eye worm) hypothetical protein 0.0882 1 1
Onchocerca volvulus 0.0008 0.0032 0.0148
Toxoplasma gondii aldehyde dehydrogenase 0.0064 0.0672 0.1163
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0025
Plasmodium falciparum histone deacetylase 1 0.0507 0.5721 1
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0006 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0036 0.0346 0.0339
Brugia malayi Cell death protein 3 precursor 0.009 0.0969 0.0963
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0006 0.0009 0.0009
Trichomonas vaginalis glucosylceramidase, putative 0.0115 0.1253 0.2181
Schistosoma mansoni acetyl-CoA synthetase 0.001 0.0059 0.0059
Trichomonas vaginalis glucosylceramidase, putative 0.0115 0.1253 0.2181
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.001 0.0049 0.0049
Schistosoma mansoni opsin-like receptor 0.0008 0.0032 0.0032
Loa Loa (eye worm) cytochrome P450 0.0012 0.0072 0.0066
Loa Loa (eye worm) hypothetical protein 0.0048 0.0492 0.0485
Brugia malayi olfactory channel protein osm-9 0.0006 0.0012 0.0006
Trypanosoma cruzi histone deacetylase, putative 0.0291 0.3261 0.5693
Trichomonas vaginalis spcc417.12 protein, putative 0.0149 0.164 0.2858
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0008 0.0032 0.0025
Loa Loa (eye worm) hypothetical protein 0.0006 0.0009 0.0003
Loa Loa (eye worm) hypothetical protein 0.0006 0.0009 0.0003
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0012 0.0072 0.0186
Echinococcus granulosus histone deacetylase 6 0.0291 0.3261 0.3261
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0012 0.0072 0.0186
Echinococcus granulosus 7tm_1 domain containing protein 0.0008 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0149 0.164 0.1634
Schistosoma mansoni histone deacetylase 0.0507 0.5721 0.5721
Schistosoma mansoni hypothetical protein 0.001 0.0049 0.0049
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.001 0.0059 0.0092
Schistosoma mansoni caspase-7 (C14 family) 0.009 0.0969 0.0969
Brugia malayi Trypsin family protein 0.001 0.0049 0.0042
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0507 0.5721 1
Echinococcus multilocularis voltage dependent calcium channel 0.0006 0.0009 0.0009
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0008 0.0032 0.0032
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.001 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0025
Mycobacterium ulcerans acyl-CoA synthetase 0.0036 0.0346 0.1868
Echinococcus multilocularis BC026374 protein (S09 family) 0.0149 0.164 0.164
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0025
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0025 0.0227 0.1153
Schistosoma mansoni cpg binding protein 0.0022 0.0195 0.0195
Echinococcus multilocularis fmrfamide receptor 0.0008 0.0032 0.0032
Echinococcus multilocularis SWI:SNF matrix associated 0.0006 0.0007 0.0007
Echinococcus granulosus potassium voltage gated channel protein 0.0006 0.0009 0.0009
Plasmodium vivax metacaspase 1, putative 0.0047 0.0473 0.0816
Brugia malayi hypothetical protein 0.0008 0.0032 0.0025
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0012 0.0072 0.011
Brugia malayi Carboxylesterase family protein 0.0882 1 1
Schistosoma mansoni tar DNA-binding protein 0.005 0.051 0.051
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0047 0.0473 0.0816
Onchocerca volvulus 0.001 0.0059 0.0306
Schistosoma mansoni amine GPCR 0.0008 0.0032 0.0032
Mycobacterium ulcerans acyl-CoA synthetase 0.0036 0.0346 0.1868
Schistosoma mansoni amine GPCR 0.0008 0.0032 0.0032
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0149 0.164 1
Schistosoma mansoni acetylcholinesterase 0.0149 0.164 0.164
Brugia malayi hypothetical protein 0.0019 0.0162 0.0155
Echinococcus multilocularis Smad4 0.0007 0.0015 0.0015
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0006 0.0009 0.0009
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0006 0.0009 0.0009
Brugia malayi G protein-coupled receptor F59B2.13 0.0008 0.0032 0.0025
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0007 0.0015 0.0015
Echinococcus multilocularis histone deacetylase 6 0.0291 0.3261 0.3261
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0014 0.0098 0.0155
Echinococcus granulosus shaker cognate 0.0006 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0025
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0012 0.0072 0.0148
Schistosoma mansoni neuropeptide F-like receptor 0.0008 0.0032 0.0032
Mycobacterium ulcerans acyl-CoA synthetase 0.001 0.0059 0.0065
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0882 1 1
Onchocerca volvulus 0.0008 0.0032 0.0148
Schistosoma mansoni tar DNA-binding protein 0.005 0.051 0.051
Echinococcus granulosus Upstream activation factor subunit UAF30 0.0006 0.0007 0.0007
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.001 0.0059 0.0065
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0149 0.164 0.164
Echinococcus granulosus hypothetical protein 0.0008 0.0032 0.0032
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0036 0.0346 0.1868
Schistosoma mansoni hypothetical protein 0.0012 0.0072 0.0072
Echinococcus granulosus voltage gated hydrogen channel 1 0.0006 0.0009 0.0009
Schistosoma mansoni histone deacetylase 4 5 0.0291 0.3261 0.3261
Loa Loa (eye worm) hypothetical protein 0.001 0.0049 0.0042
Loa Loa (eye worm) voltage-gated calcium channel 0.0006 0.0009 0.0003
Onchocerca volvulus 0.0019 0.0162 0.0904
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0008 0.0032 0.0025
Onchocerca volvulus 0.001 0.0049 0.0245
Echinococcus multilocularis serotonin receptor 0.0008 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0027 0.0243 0.0237
Leishmania major cytochrome p450-like protein 0.0012 0.0072 0.011
Trypanosoma brucei metacaspase 5, putative 0.0047 0.0473 0.0812
Schistosoma mansoni tar DNA-binding protein 0.005 0.051 0.051
Schistosoma mansoni opsin-like receptor 0.0008 0.0032 0.0032
Schistosoma mansoni aldehyde dehydrogenase 0.0064 0.0672 0.0672
Brugia malayi AMP-binding enzyme family protein 0.0036 0.0346 0.0339
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0036 0.0346 0.1868
Echinococcus granulosus tm gpcr rhodopsin 0.0008 0.0032 0.0032
Echinococcus multilocularis somatostatin receptor 0.0008 0.0032 0.0032
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0008 0.0032 0.0032
Schistosoma mansoni voltage-dependent calcium channel 0.0006 0.0009 0.0009
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0008 0.0032 0.0025
Schistosoma mansoni smad1 5 8 and 0.0007 0.0015 0.0015
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.001 0.0059 0.0104
Echinococcus multilocularis acetylcholinesterase 0.0882 1 1
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0008 0.0032 0.0032
Brugia malayi Cytochrome P450 family protein 0.0012 0.0072 0.0066
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0012 0.0072 0.0186
Loa Loa (eye worm) oxidoreductase 0.001 0.0059 0.0052
Entamoeba histolytica acyl-coA synthetase, putative 0.0036 0.0346 0.0507
Loa Loa (eye worm) histone deacetylase 7A 0.0291 0.3261 0.3256
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0149 0.164 0.2858
Onchocerca volvulus Glucosylceramidase homolog 0.0115 0.1253 0.7273
Loa Loa (eye worm) intermediate filament protein 0.0048 0.0492 0.0485
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0006 0.0009 0.0009
Schistosoma mansoni hypothetical protein 0.0006 0.0007 0.0007
Brugia malayi GnHR receptor homolog 0.0008 0.0032 0.0025
Brugia malayi hypothetical protein 0.0008 0.0032 0.0025
Echinococcus granulosus histone deacetylase 8 0.0156 0.172 0.172
Schistosoma mansoni lamin 0.0048 0.0492 0.0492
Schistosoma mansoni neuropeptide f receptor 76f 0.0008 0.0032 0.0032
Loa Loa (eye worm) TYRA-2 protein 0.0008 0.0032 0.0025
Trichomonas vaginalis glucosylceramidase, putative 0.0175 0.1941 0.3385
Leishmania major 4-coumarate:coa ligase-like protein 0.0036 0.0346 0.0589
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0012 0.0072 0.0148
Schistosoma mansoni voltage-gated cation channel 0.0006 0.0009 0.0009
Onchocerca volvulus 0.001 0.0049 0.0245
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0047 0.0473 0.0816
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0025
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0006 0.0009 0.0009
Onchocerca volvulus 0.0008 0.0032 0.0148
Trypanosoma cruzi metacaspase, putative 0.0047 0.0473 0.0812
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0006 0.0009 0.0003
Echinococcus multilocularis smad 0.0007 0.0015 0.0015
Schistosoma mansoni hypothetical protein 0.0008 0.0032 0.0032
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0012 0.0072 0.011
Schistosoma mansoni histamine h1 receptor 0.0008 0.0032 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0473 0.0816
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0025
Loa Loa (eye worm) hypothetical protein 0.0027 0.0243 0.0237
Echinococcus multilocularis MAM 0.0019 0.0162 0.0162
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0006 0.0009 0.0003
Loa Loa (eye worm) neuropeptide F receptor 0.0008 0.0032 0.0025
Trichomonas vaginalis glucosylceramidase, putative 0.0115 0.1253 0.2181
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0008 0.0032 0.0032
Loa Loa (eye worm) histone deacetylase 3 0.0507 0.5721 0.5718
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0012 0.0072 0.011
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0124 0.1349 0.1349
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0006 0.0009 0.0009
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0012 0.0072 0.0148
Echinococcus multilocularis potassium voltage gated channel protein 0.0006 0.0009 0.0009
Loa Loa (eye worm) histone deacetylase 11 0.0156 0.172 0.1714
Schistosoma mansoni voltage-gated potassium channel 0.0006 0.0009 0.0009
Echinococcus granulosus g protein coupled receptor 0.0008 0.0032 0.0032
Brugia malayi CUB domain containing protein 0.0007 0.0016 0.0009
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.001 0.0049 0.0049
Brugia malayi Transient-receptor-potential like protein 0.0006 0.0009 0.0003
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0012 0.0072 0.0148
Echinococcus granulosus tar DNA binding protein 0.005 0.051 0.051
Trypanosoma cruzi histone deacetylase 1, putative 0.0507 0.5721 1
Onchocerca volvulus 0.0149 0.164 0.9532
Plasmodium falciparum acetyl-CoA synthetase, putative 0.001 0.0059 0.0092
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0025
Echinococcus granulosus short transient receptor potential channel 6 0.0006 0.0012 0.0012
Loa Loa (eye worm) voltage-dependent calcium channel 0.0006 0.0009 0.0003
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0025
Echinococcus granulosus two pore calcium channel protein 1 0.0006 0.0009 0.0009
Echinococcus multilocularis enteropeptidase 0.001 0.0049 0.0049
Loa Loa (eye worm) MH1 domain-containing protein 0.0007 0.0015 0.0008
Echinococcus granulosus tachykinin peptides receptor 99D 0.0008 0.0032 0.0032
Echinococcus multilocularis tar DNA binding protein 0.005 0.051 0.051
Brugia malayi follicle stimulating hormone receptor 0.0008 0.0032 0.0025
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0006 0.0009 0.0009
Loa Loa (eye worm) trypsin family protein 0.001 0.0049 0.0042
Echinococcus granulosus histone deacetylase 0.0291 0.3261 0.3261
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0021 0.0178 0.0812
Echinococcus granulosus voltage dependent calcium channel 0.0006 0.0009 0.0009
Onchocerca volvulus 0.0036 0.0346 0.198
Echinococcus multilocularis g protein coupled receptor 0.0008 0.0032 0.0032
Schistosoma mansoni cpg binding protein 0.0021 0.0182 0.0182
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0006 0.0009 0.0009
Brugia malayi cation channel family protein 0.0006 0.0009 0.0003
Schistosoma mansoni BC026374 protein (S09 family) 0.0149 0.164 0.164
Onchocerca volvulus 0.001 0.0049 0.0245
Schistosoma mansoni hypothetical protein 0.001 0.0049 0.0049
Echinococcus multilocularis ryanodine receptor 44f 0.0006 0.0009 0.0009
Trichomonas vaginalis histone deacetylase, putative 0.0507 0.5721 1
Plasmodium falciparum metacaspase-like protein 0.0047 0.0473 0.0816
Echinococcus multilocularis G-protein coupled receptor, putative 0.0008 0.0032 0.0032
Brugia malayi AMP-binding enzyme family protein 0.001 0.0059 0.0052
Onchocerca volvulus 0.0006 0.0009 0.0015
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0008 0.0032 0.0032
Onchocerca volvulus 0.0008 0.0032 0.0148
Echinococcus granulosus 7TM GPCR rhodopsin 0.0008 0.0032 0.0032
Echinococcus granulosus allatostatin A receptor 0.0008 0.0032 0.0032
Onchocerca volvulus 0.0149 0.164 0.9532
Toxoplasma gondii transporter, cation channel family protein 0.0006 0.0009 0.0005
Loa Loa (eye worm) hypothetical protein 0.001 0.0049 0.0042
Trichomonas vaginalis glucosylceramidase, putative 0.0115 0.1253 0.2181
Brugia malayi hypothetical protein 0.0008 0.0032 0.0025
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.001 0.0059 0.0065
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0012 0.0072 0.0186
Schistosoma mansoni cercarial elastase (S01 family) 0.001 0.0049 0.0049
Brugia malayi Histone deacetylase 1 0.0507 0.5721 0.5718
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.001 0.0059 0.0052
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.001 0.0049 0.0049
Loa Loa (eye worm) ryanodine receptor 0.0006 0.0009 0.0003
Loa Loa (eye worm) cytochrome P450 family protein 0.0021 0.0178 0.0171
Echinococcus granulosus caspase 8 0.0047 0.0473 0.0473
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0025
Loa Loa (eye worm) hypothetical protein 0.0882 1 1
Echinococcus granulosus G protein coupled receptor 139 0.0008 0.0032 0.0032
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0012 0.0072 0.0148
Trypanosoma cruzi histone deacetylase, putative 0.0291 0.3261 0.5693
Echinococcus granulosus rhodopsin orphan GPCR 0.0008 0.0032 0.0032
Brugia malayi Muscle positioning protein 4 0.0018 0.0146 0.0139
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.001 0.0059 0.0065
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0025
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0006 0.0009 0.0003
Schistosoma mansoni voltage-gated potassium channel 0.0006 0.0009 0.0009
Brugia malayi neuropeptide F receptor 0.0008 0.0032 0.0025
Onchocerca volvulus 0.0018 0.0146 0.0813
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0025
Echinococcus multilocularis dnaJ subfamily B 0.0302 0.338 0.338
Echinococcus granulosus voltage dependent calcium channel 0.0006 0.0009 0.0009
Echinococcus granulosus alpha 1A adrenergic receptor 0.0008 0.0032 0.0032
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.001 0.0059 0.0087
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0036 0.0346 1
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0025
Entamoeba histolytica histone deacetylase, putative 0.0507 0.5721 1
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0012 0.0072 0.0186
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0008 0.0032 0.0032
Echinococcus multilocularis Upstream activation factor subunit UAF30 0.0006 0.0007 0.0007
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0008 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.001 0.0059 0.0052
Schistosoma mansoni biogenic amine receptor 0.0008 0.0032 0.0032
Trichomonas vaginalis histone deacetylase, putative 0.0507 0.5721 1
Brugia malayi exodeoxyribonuclease III family protein 0.0014 0.0098 0.0091
Schistosoma mansoni cercarial elastase (S01 family) 0.001 0.0049 0.0049
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0047 0.0473 0.0816
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0008 0.0032 0.0032
Schistosoma mansoni histone deacetylase 1 2 3 0.0156 0.172 0.172
Brugia malayi Cytochrome P450 family protein 0.0021 0.0178 0.0171
Schistosoma mansoni hypothetical protein 0.0008 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0025
Schistosoma mansoni brg-1 associated factor 0.0006 0.0007 0.0007
Trichomonas vaginalis glucosylceramidase, putative 0.0115 0.1253 0.2181
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0025
Brugia malayi AMP-binding enzyme family protein 0.001 0.0059 0.0052
Echinococcus granulosus TGF beta signal transducer SmadC 0.0007 0.0015 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0473 0.0816
Brugia malayi hypothetical protein 0.001 0.0049 0.0042
Loa Loa (eye worm) hypothetical protein 0.0116 0.1262 0.1256
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0012 0.0072 0.0148
Echinococcus multilocularis transient receptor potential cation channel 0.0006 0.0009 0.0009
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0006 0.0009 0.0009
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.001 0.0059 0.0087
Schistosoma mansoni amine GPCR 0.0008 0.0032 0.0032
Echinococcus multilocularis calcium activated potassium channel 0.0006 0.0009 0.0009
Loa Loa (eye worm) G-protein coupled receptor 0.0008 0.0032 0.0025
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0047 0.0473 0.0816
Brugia malayi Serotonin receptor 0.0008 0.0032 0.0025
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0672 0.3914
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0012 0.0072 0.0186
Loa Loa (eye worm) G-protein coupled receptor 0.0008 0.0032 0.0025
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0012 0.0072 0.0148
Echinococcus multilocularis neuropeptides capa receptor 0.0008 0.0032 0.0032
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0006 0.0009 0.0009
Plasmodium falciparum metacaspase 1 0.0047 0.0473 0.0816
Echinococcus granulosus transient receptor potential cation channel 0.0006 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0025
Onchocerca volvulus 0.0048 0.0492 0.283
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0012 0.0072 0.0186
Echinococcus multilocularis hyperpolarization activated cyclic 0.0006 0.0009 0.0009
Brugia malayi Melatonin receptor type 1A 0.0008 0.0032 0.0025
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0025 0.0227 0.1153
Schistosoma mansoni voltage-gated potassium channel 0.0006 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0149 0.164 0.1634
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0014 0.0098 0.0155
Loa Loa (eye worm) MH2 domain-containing protein 0.0096 0.104 0.1034
Plasmodium vivax histone deacetylase, putative 0.0291 0.3261 0.5695
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0012 0.0072 0.0186
Trypanosoma brucei acetyl-CoA synthetase, putative 0.001 0.0059 0.0087
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0036 0.0346 0.1899
Trypanosoma cruzi metacaspase 5, putative 0.0047 0.0473 0.0812
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0149 0.164 1
Trichomonas vaginalis histone deacetylase, putative 0.0507 0.5721 1
Echinococcus granulosus para nitrobenzyl esterase 0.0149 0.164 0.164
Echinococcus granulosus rhodopsin orphan GPCR 0.0008 0.0032 0.0032
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0008 0.0032 0.0025
Loa Loa (eye worm) hypothetical protein 0.0149 0.164 0.1634
Schistosoma mansoni hypothetical protein 0.0006 0.0007 0.0007
Echinococcus multilocularis rhodopsin orphan GPCR 0.0008 0.0032 0.0032
Echinococcus granulosus histone deacetylase 3 0.0507 0.5721 0.5721
Schistosoma mansoni hypothetical protein 0.0019 0.0162 0.0162
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0006 0.0009 0.0003
Leishmania major 4-coumarate:coa ligase-like protein 0.0036 0.0346 0.0589
Plasmodium vivax acyl-CoA synthetase, putative 0.0027 0.0243 0.0414
Loa Loa (eye worm) hypothetical protein 0.001 0.0059 0.0052
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0012 0.0072 0.0186
Schistosoma mansoni smad 0.0007 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0025
Brugia malayi Histone deacetylase family protein 0.0291 0.3261 0.3256
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0025
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0006 0.0009 0.0003
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.001 0.0059 0.0104
Echinococcus granulosus potassium voltage gated channel protein 0.0006 0.0009 0.0009
Echinococcus granulosus Mastin 0.001 0.0049 0.0049
Brugia malayi cytoplasmic intermediate filament protein 0.0026 0.0236 0.0229
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.001 0.0059 0.0104
Schistosoma mansoni cercarial elastase (S01 family) 0.001 0.0049 0.0049
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0007 0.0015 0.0015
Trypanosoma cruzi histone deacetylase 1, putative 0.0507 0.5721 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0008 0.0032 0.0032
Brugia malayi histone deacetylase 3 (HD3) 0.0507 0.5721 0.5718
Echinococcus granulosus orexin receptor type 2 0.0008 0.0032 0.0032
Schistosoma mansoni neuropeptide receptor 0.0008 0.0032 0.0032
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0006 0.0009 0.0009
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0012 0.0072 0.0186
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0008 0.0032 0.0025
Loa Loa (eye worm) hypothetical protein 0.0149 0.164 0.1634
Loa Loa (eye worm) melatonin receptor type 1A 0.0008 0.0032 0.0025
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0025
Echinococcus multilocularis sex peptide receptor 0.0008 0.0032 0.0032
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0036 0.0346 1
Brugia malayi Cyclic-nucleotide gated cation channel 0.0006 0.0009 0.0003
Mycobacterium tuberculosis Carboxylesterase LipT 0.0149 0.164 1
Onchocerca volvulus 0.001 0.0049 0.0245
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0008 0.0032 0.0032
Echinococcus multilocularis voltage gated potassium channel 0.0006 0.0009 0.0009
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0008 0.0032 0.0032
Echinococcus multilocularis short transient receptor potential channel 6 0.0006 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0006 0.0009 0.0003
Echinococcus granulosus fmrfamide receptor 0.0008 0.0032 0.0032
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.062 0.7007 0.7007
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0036 0.0346 0.1868
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.001 0.0059 0.0104
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0006 0.0009 0.0003
Echinococcus multilocularis cpg binding protein 0.0022 0.0195 0.0195
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0008 0.0032 0.0032
Trichomonas vaginalis histone deacetylase, putative 0.0507 0.5721 1
Schistosoma mansoni cercarial elastase (S01 family) 0.001 0.0049 0.0049
Toxoplasma gondii histone deacetylase HDAC3 0.0507 0.5721 1
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0014 0.0098 0.031
Schistosoma mansoni intermediate filament proteins 0.0048 0.0492 0.0492
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0473 0.0816
Echinococcus multilocularis apoptotic protease activating factor 1 0.0044 0.0436 0.0436
Schistosoma mansoni caspase-3 (C14 family) 0.0124 0.1349 0.1349
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0008 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.001 0.0049 0.0042
Brugia malayi CXXC zinc finger family protein 0.0021 0.0182 0.0175
Schistosoma mansoni caspase-7 (C14 family) 0.0124 0.1349 0.1349
Loa Loa (eye worm) hypothetical protein 0.0019 0.0162 0.0155
Loa Loa (eye worm) hypothetical protein 0.0162 0.1783 0.1778
Onchocerca volvulus 0.0149 0.164 0.9532
Echinococcus multilocularis neuropeptide Y receptor 0.0008 0.0032 0.0032
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0008 0.0032 0.0032
Echinococcus multilocularis conserved hypothetical protein 0.0006 0.0009 0.0009
Trypanosoma brucei Metacaspase-4 0.0047 0.0473 0.0812
Plasmodium vivax hypothetical protein, conserved 0.0047 0.0473 0.0816
Onchocerca volvulus 0.0018 0.0146 0.0813
Loa Loa (eye worm) hypothetical protein 0.0006 0.0009 0.0003
Toxoplasma gondii histone deacetylase HDAC5 0.0156 0.1723 0.3004
Loa Loa (eye worm) hypothetical protein 0.0006 0.0009 0.0003
Echinococcus granulosus neuropeptide receptor 0.0008 0.0032 0.0032
Echinococcus granulosus sodium leak channel non selective protein 0.0006 0.0009 0.0009
Brugia malayi hypothetical protein 0.0044 0.0436 0.043
Echinococcus granulosus neuropeptides capa receptor 0.0008 0.0032 0.0032
Toxoplasma gondii hypothetical protein 0.0006 0.0009 0.0005
Schistosoma mansoni voltage-gated potassium channel 0.0006 0.0009 0.0009
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0012 0.0072 0.0148
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0012 0.0072 0.0148
Trypanosoma brucei histone deacetylase 4 0.0291 0.3261 0.5693
Echinococcus granulosus sodium channel protein 0.0006 0.0009 0.0009
Brugia malayi AMP-binding enzyme family protein 0.001 0.0059 0.0052
Onchocerca volvulus 0.0008 0.0032 0.0148
Mycobacterium ulcerans acyl-CoA synthetase 0.001 0.0059 0.0065
Loa Loa (eye worm) hypothetical protein 0.0022 0.0196 0.019
Onchocerca volvulus 0.0008 0.0032 0.0148
Schistosoma mansoni neuropeptide receptor 0.0008 0.0032 0.0032
Trichomonas vaginalis ap endonuclease, putative 0.0014 0.0098 0.016
Echinococcus multilocularis g protein coupled receptor 0.0008 0.0032 0.0032
Brugia malayi hypothetical protein 0.0008 0.0032 0.0025
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0008 0.0032 0.0032
Onchocerca volvulus 0.0018 0.0146 0.0813
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0047 0.0473 0.0816
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0045 0.0452 0.0452
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.001 0.0059 0.0087
Trichomonas vaginalis glucosylceramidase, putative 0.0115 0.1253 0.2181
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0507 0.5721 1
Echinococcus granulosus smad 0.0007 0.0015 0.0015
Schistosoma mansoni neuropeptide receptor 0.0008 0.0032 0.0032
Schistosoma mansoni transient receptor potential channel 0.0006 0.0012 0.0012
Schistosoma mansoni aldehyde dehydrogenase 0.0064 0.0672 0.0672
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0064 0.0672 0.0672
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0008 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0156 0.172 0.1714
Loa Loa (eye worm) voltage-gated potassium channel 0.0006 0.0009 0.0003
Echinococcus granulosus histone deacetylase 6 0.0294 0.3298 0.3298
Loa Loa (eye worm) hypothetical protein 0.0009 0.0046 0.0039
Loa Loa (eye worm) hypothetical protein 0.0018 0.0146 0.0139
Onchocerca volvulus 0.001 0.0049 0.0245
Brugia malayi AMP-binding enzyme family protein 0.0036 0.0346 0.0339
Brugia malayi larval opioid receptor 0.0008 0.0032 0.0025
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0025
Mycobacterium ulcerans acyl-CoA synthetase 0.0036 0.0346 0.1868
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0025
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0008 0.0032 0.0025
Trichomonas vaginalis antibiotic synthetase, putative 0.001 0.0059 0.0092
Trichomonas vaginalis glucosylceramidase, putative 0.0121 0.1323 0.2304
Brugia malayi RNA recognition motif domain containing protein 0.005 0.051 0.0504
Loa Loa (eye worm) carboxylesterase 0.0149 0.164 0.1634
Schistosoma mansoni calcium-activated potassium channel 0.0006 0.0009 0.0009
Schistosoma mansoni voltage-gated ion channel 0.0006 0.0009 0.0009
Leishmania major histone deacetylase, putative 0.0291 0.3261 0.5693
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0006 0.0009 0.0009
Toxoplasma gondii transporter, cation channel family protein 0.0006 0.0009 0.0005
Echinococcus granulosus g protein coupled receptor 0.0008 0.0032 0.0032
Leishmania major metacaspase, putative 0.0047 0.0473 0.0812
Trichomonas vaginalis ap endonuclease, putative 0.0014 0.0098 0.016
Loa Loa (eye worm) DOMON domain-containing protein 0.0018 0.0146 0.0139
Loa Loa (eye worm) hypothetical protein 0.0023 0.0206 0.02
Schistosoma mansoni myosin xvIII 0.0008 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0149 0.164 0.1634
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0006 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0025
Plasmodium vivax histone deacetylase, putative 0.0156 0.172 0.2998
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0026 0.0236 0.0229
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0006 0.0009 0.0003
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0006 0.0009 0.0005
Loa Loa (eye worm) CXXC zinc finger family protein 0.0021 0.0182 0.0175
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0006 0.0009 0.0009
Brugia malayi Carboxylesterase family protein 0.0149 0.164 0.1634
Echinococcus multilocularis neuropeptide s receptor 0.0321 0.3596 0.3596
Loa Loa (eye worm) histone methyltransferase 0.0007 0.0015 0.0008
Onchocerca volvulus 0.0008 0.0032 0.0148
Echinococcus granulosus neuroligin 0.0149 0.164 0.164
Brugia malayi Dopamine receptor 0.0008 0.0032 0.0025
Brugia malayi Tachykinin-like peptides receptor 99D 0.0008 0.0032 0.0025
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0025
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0025
Echinococcus multilocularis caspase 0.0124 0.1349 0.1349
Echinococcus multilocularis short transient receptor potential channel 6 0.0006 0.0012 0.0012
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0008 0.0032 0.0032
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0023 0.0206 0.0206
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0007 0.0015 0.0015
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.001 0.0059 0.0059

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 0.57 nM BindingDB_Patents: Inhibition Assay. Inhibition assay using human enteropeptidase. ChEMBL. No reference
Ki (binding) = 0.57 nM BindingDB_Patents: Inhibition Assay. Inhibition assay using human enteropeptidase. ChEMBL. No reference
Ki (binding) = 0.86 nM BindingDB_Patents: Inhibition Assay. Inhibition assay using human trysin. ChEMBL. No reference
Ki (binding) = 0.86 nM BindingDB_Patents: Inhibition Assay. Inhibition assay using human trysin. ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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