TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 476.013 | Formula: C27H30ClN5O
H donors: 2 H acceptors: 2 LogP: 4.2 Rotable bonds: 5
Rule of 5 violations (Lipinski): 1
SMILES: Clc1cccc(c1)c1cc(C(=O)N)c2c(n1)c1ccc(cc1[nH]2)CN1CCN(CC1)C(C)(C)C
InChi: 1S/C27H30ClN5O/c1-27(2,3)33-11-9-32(10-12-33)16-17-7-8-20-23(13-17)31-25-21(26(29)34)15-22(30-24(20)25)18-5-4-6-19(28)14-18/h4-8,13-15,31H,9-12,16H2,1-3H3,(H2,29,34)
InChiKey: AZFUIAUYFDLNCL-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species	Target name	Source	Bibliographic reference
Homo sapiens	Janus kinase 2	Starlite/ChEMBL	No references

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Loa Loa (eye worm)	hypothetical protein	0.0038	1	1
Loa Loa (eye worm)	hypothetical protein	0.0038	1	1
Onchocerca volvulus		0.0013	0.2022	0.2022
Brugia malayi	Protein kinase domain containing protein	0.0008	0.0149	0.0149
Brugia malayi	Nuclear hormone receptor family member nhr-41	0.0009	0.0591	0.0591
Echinococcus multilocularis	tyrosine protein kinase Src42A	0.0008	0.0149	0.0149
Onchocerca volvulus	Steroid hormone receptor family member cnr14 homolog	0.0009	0.0591	0.0591
Loa Loa (eye worm)	hypothetical protein	0.0013	0.2022	0.2022
Echinococcus multilocularis	c src tyrosine kinase	0.0008	0.0149	0.0149
Loa Loa (eye worm)	SRC-1	0.0008	0.0149	0.0149
Brugia malayi	Peroxidasin	0.0038	1	1
Brugia malayi	hypothetical protein	0.0013	0.2022	0.2022
Brugia malayi	Ligand-binding domain of nuclear hormone receptor family protein	0.0009	0.0591	0.0591
Echinococcus multilocularis	thyroid hormone receptor alpha	0.0009	0.0591	0.0591
Loa Loa (eye worm)	TK protein kinase	0.0008	0.0149	0.0149
Loa Loa (eye worm)	hypothetical protein	0.0038	1	1
Brugia malayi	photoreceptor-specific nuclear receptor	0.0009	0.0591	0.0591
Loa Loa (eye worm)	TK/FER protein kinase	0.0008	0.0149	0.0149
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0008	0.0149	0.0149
Echinococcus granulosus	ecdysone induced protein 78C	0.0009	0.0591	0.0591
Onchocerca volvulus		0.0013	0.2022	0.2022
Echinococcus granulosus	c4b binding protein beta chain	0.0013	0.2022	0.2022
Loa Loa (eye worm)	hypothetical protein	0.0009	0.0591	0.0591
Loa Loa (eye worm)	hypothetical protein	0.0009	0.0591	0.0591
Loa Loa (eye worm)	TK/FER protein kinase	0.0008	0.0149	0.0149
Loa Loa (eye worm)	hypothetical protein	0.0038	1	1
Echinococcus multilocularis	tyrosine protein kinase Fgr	0.0008	0.0149	0.0149
Loa Loa (eye worm)	hypothetical protein	0.0038	1	1
Loa Loa (eye worm)	animal heme peroxidase	0.0038	1	1
Brugia malayi	Protein kinase domain containing protein	0.0008	0.0149	0.0149
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0008	0.0149	0.0149
Loa Loa (eye worm)	hypothetical protein	0.0013	0.2022	0.2022
Echinococcus granulosus	COUP TF:Svp nuclear hormone receptor	0.0009	0.0591	0.0591
Schistosoma mansoni	tyrosine kinase	0.0008	0.0149	0.0149
Loa Loa (eye worm)	TK/FER protein kinase	0.0008	0.0149	0.0149
Loa Loa (eye worm)	hypothetical protein	0.0013	0.2022	0.2022
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0008	0.0149	0.0149
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0008	0.0149	0.0149
Brugia malayi	Nuclear hormone receptor family member nhr-19	0.0009	0.0591	0.0591
Echinococcus granulosus	tyrosine protein kinase ABL1	0.0008	0.0149	0.0149
Loa Loa (eye worm)	hypothetical protein	0.0038	1	1
Onchocerca volvulus		0.0009	0.0591	0.0591
Loa Loa (eye worm)	hypothetical protein	0.0009	0.0591	0.0591
Brugia malayi	Nuclear hormone receptor family member nhr-25	0.0009	0.0591	0.0591
Onchocerca volvulus	Peroxidase homolog	0.0038	1	1
Onchocerca volvulus	Chorion peroxidase homolog	0.0038	1	1
Onchocerca volvulus		0.0013	0.2022	0.2022
Echinococcus granulosus	3'partial\|tyrosine protein kinase Fgr	0.0008	0.0149	0.0149
Echinococcus multilocularis	tyrosine protein kinase Srms	0.0008	0.0149	0.0149
Brugia malayi	pregnancy-associated plasma protein-A	0.0013	0.2022	0.2022
Brugia malayi	hypothetical protein	0.0013	0.2022	0.2022
Loa Loa (eye worm)	hypothetical protein	0.0038	1	1
Onchocerca volvulus		0.0013	0.2022	0.2022
Loa Loa (eye worm)	hypothetical protein	0.0013	0.2022	0.2022
Echinococcus multilocularis	FTZ F1 alpha	0.0009	0.0591	0.0591
Schistosoma mansoni	c4b-binding protein beta chain	0.0013	0.2022	0.2022
Loa Loa (eye worm)	TK/ABL protein kinase	0.0008	0.0149	0.0149
Onchocerca volvulus		0.0013	0.2022	0.2022
Brugia malayi	Sushi domain	0.0013	0.2022	0.2022
Onchocerca volvulus	Bile acid receptor homolog	0.0009	0.0591	0.0591
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0009	0.0591	0.0591
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-14	0.0009	0.0591	0.0591
Loa Loa (eye worm)	hypothetical protein	0.0013	0.2022	0.2022
Onchocerca volvulus	Dual oxidase homolog	0.0038	1	1
Loa Loa (eye worm)	hypothetical protein	0.0038	1	1
Loa Loa (eye worm)	TK/FER protein kinase	0.0008	0.0149	0.0149
Loa Loa (eye worm)	hypothetical protein	0.0013	0.2022	0.2022
Loa Loa (eye worm)	TK/FER protein kinase	0.0008	0.0149	0.0149
Onchocerca volvulus	Peroxidasin homolog	0.0038	1	1
Echinococcus multilocularis	tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase	0.0008	0.0149	0.0149
Schistosoma mansoni	retinoid-x-receptor (RXR)	0.0009	0.0591	0.0591
Brugia malayi	Protein kinase domain containing protein	0.0008	0.0149	0.0149
Loa Loa (eye worm)	blistered cuticle protein 3	0.0038	1	1
Loa Loa (eye worm)	hypothetical protein	0.0009	0.0591	0.0591
Echinococcus granulosus	tyrosine kinase	0.0008	0.0149	0.0149
Echinococcus granulosus	FTZ F1 alpha	0.0009	0.0591	0.0591
Loa Loa (eye worm)	TK/FER protein kinase	0.0008	0.0149	0.0149
Loa Loa (eye worm)	hypothetical protein	0.0009	0.0591	0.0591
Loa Loa (eye worm)	TK/FER protein kinase	0.0008	0.0149	0.0149
Brugia malayi	hypothetical protein	0.0013	0.2022	0.2022
Echinococcus granulosus	retinoic acid receptor rxr beta a	0.0009	0.0591	0.0591
Echinococcus granulosus	Nuclear hormone receptor family member nhr 41	0.0009	0.0591	0.0591
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-1	0.0009	0.0591	0.0591
Brugia malayi	Protein kinase domain containing protein	0.0008	0.0149	0.0149
Schistosoma mansoni	retinoic acid receptor RXR	0.0009	0.0591	0.0591
Echinococcus multilocularis	tyrosine protein kinase Blk	0.0008	0.0149	0.0149
Echinococcus multilocularis	tyrosine protein kinase Abl	0.0008	0.0149	0.0149
Echinococcus multilocularis	hepatocyte nuclear factor 4 alpha	0.0009	0.0591	0.0591
Brugia malayi	hypothetical protein	0.0013	0.2022	0.2022
Brugia malayi	protein-tyrosine kinase	0.0008	0.0149	0.0149
Brugia malayi	steroid hormone receptor	0.0009	0.0591	0.0591
Schistosoma mansoni	proto-oncogene tyrosine-protein kinase src	0.0008	0.0149	0.0149
Brugia malayi	Animal haem peroxidase family protein	0.0038	1	1
Echinococcus multilocularis	FTZ F1 nuclear receptor protein	0.0009	0.0591	0.0591
Toxoplasma gondii	rhoptry neck protein RON1	0.0013	0.2022	1
Brugia malayi	Nuclear hormone receptor family member nhr-49	0.0009	0.0591	0.0591
Brugia malayi	GCC2 and GCC3 family protein	0.0021	0.441	0.441
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0009	0.0591	0.0591
Onchocerca volvulus		0.0008	0.0149	0.0149
Onchocerca volvulus		0.0013	0.2022	0.2022
Loa Loa (eye worm)	pregnancy-associated plasma protein-E	0.0013	0.2022	0.2022
Echinococcus granulosus	tyrosine kinase	0.0008	0.0149	0.0149
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-41	0.0009	0.0591	0.0591
Echinococcus multilocularis	Nuclear hormone receptor family member nhr 41	0.0009	0.0591	0.0591
Echinococcus multilocularis	tyrosine protein kinase Btk29A	0.0008	0.0149	0.0149
Loa Loa (eye worm)	animal heme peroxidase	0.0038	1	1
Onchocerca volvulus		0.0038	1	1
Echinococcus granulosus	tyrosine protein kinase Lyn	0.0008	0.0149	0.0149
Echinococcus multilocularis	c4b binding protein beta chain	0.0013	0.2022	0.2022
Echinococcus multilocularis	tyrosine kinase	0.0008	0.0149	0.0149
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-49	0.0009	0.0591	0.0591
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0008	0.0149	0.0149
Loa Loa (eye worm)	animal heme peroxidase	0.0038	1	1
Onchocerca volvulus		0.0008	0.0149	0.0149
Schistosoma mansoni	tyrosine kinase	0.0008	0.0149	0.0149
Onchocerca volvulus	Peroxidasin homolog	0.0038	1	1
Echinococcus granulosus	tyrosine protein kinase Blk	0.0008	0.0149	0.0149
Loa Loa (eye worm)	hypothetical protein	0.0013	0.2022	0.2022
Schistosoma mansoni	tyrosine kinase	0.0008	0.0149	0.0149
Toxoplasma gondii	rhoptry neck protein RON9	0.0013	0.2022	1
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0008	0.0149	0.0149
Brugia malayi	ecdysteroid receptor	0.0009	0.0591	0.0591
Schistosoma mansoni	tyrosine kinase	0.0008	0.0149	0.0149
Loa Loa (eye worm)	hypothetical protein	0.0009	0.0591	0.0591
Onchocerca volvulus		0.0038	1	1
Echinococcus multilocularis	C type lectin domian containing protein	0.0013	0.2022	0.2022
Loa Loa (eye worm)	TK/FER protein kinase	0.0008	0.0149	0.0149
Brugia malayi	SRC-1	0.0008	0.0149	0.0149
Loa Loa (eye worm)	hypothetical protein	0.0038	1	1
Brugia malayi	hypothetical protein	0.0008	0.0149	0.0149
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0009	0.0591	0.0591
Schistosoma mansoni	photoreceptor-specific nuclear receptor related	0.0009	0.0591	0.0591
Loa Loa (eye worm)	hypothetical protein	0.0009	0.0591	0.0591
Brugia malayi	Animal haem peroxidase family protein	0.0038	1	1
Echinococcus granulosus	proto oncogene tyrosine protein kinase LCK	0.0008	0.0149	0.0149
Echinococcus granulosus	tyrosine protein kinase Btk29A	0.0008	0.0149	0.0149
Brugia malayi	nuclear hormone receptor	0.0009	0.0591	0.0591
Echinococcus multilocularis	proto oncogene tyrosine protein kinase LCK	0.0008	0.0149	0.0149
Echinococcus granulosus	tyrosine protein kinase Srms	0.0008	0.0149	0.0149
Onchocerca volvulus	Protein ultraspiracle homolog	0.0009	0.0591	0.0591
Schistosoma mansoni	tyrosine kinase	0.0008	0.0149	0.0149
Loa Loa (eye worm)	TK/FER protein kinase	0.0008	0.0149	0.0149
Schistosoma mansoni	nuclear receptor 2DBD-gamma	0.0009	0.0591	0.0591
Echinococcus multilocularis	tyrosine protein kinase Fps85D	0.0008	0.0149	0.0149
Onchocerca volvulus		0.0038	1	1
Schistosoma mansoni	FTZ-F1 nuclear receptor-like protein	0.0009	0.0591	0.0591
Schistosoma mansoni	peroxidasin	0.0038	1	1
Loa Loa (eye worm)	hypothetical protein	0.0015	0.2517	0.2517
Loa Loa (eye worm)	TK/FER protein kinase	0.0008	0.0149	0.0149
Brugia malayi	Animal haem peroxidase family protein	0.0038	1	1
Loa Loa (eye worm)	animal heme peroxidase	0.0038	1	1
Brugia malayi	Animal haem peroxidase family protein	0.0038	1	1
Schistosoma mansoni	steroid hormone receptor ad4bp	0.0009	0.0591	0.0591
Brugia malayi	Nuclear hormone receptor family member nhr-3	0.0009	0.0591	0.0591
Brugia malayi	Nuclear hormone receptor family member nhr-31	0.0009	0.0591	0.0591
Schistosoma mansoni	RAR-like nuclear receptor	0.0009	0.0591	0.0591
Onchocerca volvulus	Peroxidase homolog	0.0038	1	1
Loa Loa (eye worm)	nuclear Hormone Receptor family member	0.0009	0.0591	0.0591
Loa Loa (eye worm)	steroid hormone receptor	0.0009	0.0591	0.0591
Onchocerca volvulus		0.0013	0.2022	0.2022
Brugia malayi	Nuclear hormone receptor family member nhr-40	0.0009	0.0591	0.0591
Plasmodium falciparum	apical sushi protein	0.0013	0.2022	0.5
Onchocerca volvulus		0.0008	0.0149	0.0149
Onchocerca volvulus		0.0008	0.0149	0.0149
Loa Loa (eye worm)	hypothetical protein	0.0038	1	1
Brugia malayi	Tyrosine-protein kinase abl-1	0.0008	0.0149	0.0149
Brugia malayi	SH2 domain containing protein	0.0008	0.0149	0.0149
Loa Loa (eye worm)	hypothetical protein	0.0021	0.441	0.441
Echinococcus granulosus	tyrosine kinase\|tyrosine protein kinase Fyn	0.0008	0.0149	0.0149
Schistosoma mansoni	nuclear hormone receptor nor-1/nor-2	0.0009	0.0591	0.0591
Brugia malayi	Animal haem peroxidase family protein	0.0038	1	1
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0008	0.0149	0.0149
Onchocerca volvulus		0.0013	0.2022	0.2022
Onchocerca volvulus		0.0008	0.0149	0.0149
Brugia malayi	SH2 domain containing protein	0.0008	0.0149	0.0149
Brugia malayi	hypothetical protein	0.0013	0.2022	0.2022
Onchocerca volvulus		0.0008	0.0149	0.0149
Onchocerca volvulus		0.0013	0.2022	0.2022
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-40	0.0009	0.0591	0.0591
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-31	0.0009	0.0591	0.0591
Echinococcus granulosus	peroxidasin	0.0038	1	1
Echinococcus granulosus	tyrosine protein kinase Src42A	0.0008	0.0149	0.0149
Entamoeba histolytica	SH2-protein kinase domain containing protein	0.0008	0.0149	0.5
Echinococcus multilocularis	COUP TF:Svp nuclear hormone receptor	0.0009	0.0591	0.0591
Loa Loa (eye worm)	hypothetical protein	0.0009	0.0591	0.0591
Brugia malayi	hypothetical protein	0.0013	0.2022	0.2022
Schistosoma mansoni	tyrosine kinase	0.0008	0.0149	0.0149
Echinococcus multilocularis	tyrosine protein kinase lyn tyrosine protein kinase blk	0.0008	0.0149	0.0149
Brugia malayi	Blistered cuticle protein 3	0.0038	1	1
Brugia malayi	Nuclear hormone receptor family member nhr-1	0.0009	0.0591	0.0591
Brugia malayi	nuclear receptor NHR-88	0.0009	0.0591	0.0591
Brugia malayi	Ligand-binding domain of nuclear hormone receptor family protein	0.0009	0.0591	0.0591
Echinococcus multilocularis	tyrosine protein kinase shark	0.0008	0.0149	0.0149
Echinococcus granulosus	c src tyrosine kinase	0.0008	0.0149	0.0149
Schistosoma mansoni	thyroid hormone receptor	0.0009	0.0591	0.0591
Plasmodium vivax	apical sushi protein, putative	0.0013	0.2022	0.5
Onchocerca volvulus		0.0013	0.2022	0.2022
Brugia malayi	hypothetical protein	0.0013	0.2022	0.2022
Echinococcus multilocularis	tyrosine protein kinase ABL1	0.0008	0.0149	0.0149
Schistosoma mansoni	Tr4/Tr2 (homologue)	0.0009	0.0591	0.0591
Brugia malayi	Nuclear hormone receptor-like 1	0.0009	0.0591	0.0591
Echinococcus granulosus	FTZ F1 nuclear receptor protein	0.0009	0.0591	0.0591
Echinococcus granulosus	tyrosine protein kinase Fps85D	0.0008	0.0149	0.0149
Echinococcus multilocularis	peroxidasin	0.0038	1	1
Echinococcus granulosus	tyrosine protein kinase Src64B	0.0008	0.0149	0.0149
Loa Loa (eye worm)	hypothetical protein	0.0038	1	1
Brugia malayi	Protein kinase domain containing protein	0.0008	0.0149	0.0149
Schistosoma mansoni	thyroid hormone receptor	0.0009	0.0591	0.0591
Loa Loa (eye worm)	hypothetical protein	0.0038	1	1
Brugia malayi	Steroid receptor seven-up type 2	0.0009	0.0591	0.0591
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0009	0.0591	0.0591
Giardia lamblia	High cysteine protein	0.0007	0	0.5
Echinococcus multilocularis	tyrosine protein kinase Src64B	0.0008	0.0149	0.0149
Schistosoma mansoni	coup transcription factor	0.0009	0.0591	0.0591
Brugia malayi	Nuclear hormone receptor family member nhr-25	0.0009	0.0591	0.0591
Brugia malayi	Nuclear hormone receptor family member nhr-19	0.0009	0.0591	0.0591
Echinococcus granulosus	hepatocyte nuclear factor 4 alpha	0.0009	0.0591	0.0591
Echinococcus granulosus	tyrosine protein kinase shark	0.0008	0.0149	0.0149
Echinococcus granulosus	C type lectin domian containing protein	0.0013	0.2022	0.2022
Echinococcus multilocularis	ecdysone induced protein 78C	0.0009	0.0591	0.0591
Loa Loa (eye worm)	hypothetical protein	0.0038	1	1
Loa Loa (eye worm)	hypothetical protein	0.0038	1	1
Schistosoma mansoni	nuclear hormone receptor	0.0009	0.0591	0.0591
Schistosoma mansoni	peroxidasin	0.0038	1	1
Loa Loa (eye worm)	hypothetical protein	0.0008	0.0149	0.0149
Brugia malayi	Nuclear hormone receptor family member nhr-14	0.0009	0.0591	0.0591

Activities

Activity type	Activity value	Assay description	Source	Reference
IC50 (binding)	= 1 nM	BindingDB_Patents: Tyrosine Kinase Assay. The assays were performed in V-bottom 384-well plates. The final assay volume was 30 ul prepared from 15 ul additions of enzyme and substrates (fluoresceinated peptide and ATP) and test compounds in assay buffer (100 mM HEPES pH 7.4, 10 mM MgCl2, 25 mM Beta-Glycerolphosphate, 0.015% Brij35 and 4 mM DTT). The reaction was initiated by the combination of JAK2 with substrates and test compounds. The reaction was incubated at room temperature for 60 min. and terminated by adding 45 ul of 35 mM EDTA to each sample. The reaction mixture was analyzed on the Caliper LABCHIP 3000 by electrophoretic separation of the fluorescent substrate and phosphorylated product. Inhibition data were calculated by comparison to no enzyme control reactions for 100% inhibition and vehicle-only reactions for 0% inhibition. The final concentration of reagents in the assays is ATP, 30 uM; JAK2 fluorescent peptide, 1.5 uM; JAK2, 1 nM; and DMSO, 1.6%.	ChEMBL.	No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL3649606

Bibliographic References

No literature references available for this target.

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Detailed information for compound 1999895