Detailed information for compound 201707

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 567.607 | Formula: C29H29NO9S
  • H donors: 0 H acceptors: 6 LogP: 2.38 Rotable bonds: 11
    Rule of 5 violations (Lipinski): 2
  • SMILES: CC(=O)OCC1=C(C(=O)OC(c2ccccc2)c2ccccc2)N2C(S(=O)(=O)C1)/C(=C\C(=O)OC(C)(C)C)/C2=O
  • InChi: 1S/C29H29NO9S/c1-18(31)37-16-21-17-40(35,36)27-22(15-23(32)39-29(2,3)4)26(33)30(27)24(21)28(34)38-25(19-11-7-5-8-12-19)20-13-9-6-10-14-20/h5-15,25,27H,16-17H2,1-4H3/b22-15-
  • InChiKey: ZVHUMLFCTLQGPY-JCMHNJIXSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0003 0.0003
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0036 0.0016 0.0324
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.002 0.0003 0.0003
Onchocerca volvulus 0.002 0.0003 0.0063
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0019 0.0003 0.0003
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0595 0.0427 1
Echinococcus granulosus Regulator of G protein signaling 20 0.002 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0036 0.0016 0.0016
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0017 0.0376
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Brugia malayi PHD-finger family protein 0.0018 0.0002 0.0002
Echinococcus granulosus kelch ECH associated protein 1 like 0.0093 0.0057 0.0057
Echinococcus multilocularis G protein coupled receptor 139 0.0019 0.0003 0.0003
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.002 0.0003 0.0057
Loa Loa (eye worm) nuclear hormone receptor 0.0075 0.0044 0.0044
Mycobacterium tuberculosis Probable short chain alcohol dehydrogenase/reductase 0.002 0.0003 0.0057
Schistosoma mansoni short chain dehydrogenase 0.002 0.0003 0.0003
Loa Loa (eye worm) G-protein coupled receptor 0.0019 0.0003 0.0003
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0158 0.0105 0.0105
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0084 0.005 0.0067
Onchocerca volvulus 0.0019 0.0003 0.0053
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0002 0.0002
Onchocerca volvulus 0.0055 0.0029 0.0559
Mycobacterium ulcerans oxidoreductase 0.002 0.0003 0.0024
Loa Loa (eye worm) hypothetical protein 0.0075 0.0044 0.0044
Schistosoma mansoni nuclear hormone receptor 0.0075 0.0044 0.0044
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0089 0.0054 0.1259
Onchocerca volvulus Pyruvate kinase homolog 0.0267 0.0186 0.3542
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0095 0.0059 0.0059
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0019 0.0003 0.0003
Brugia malayi Uncoordinated protein 44 0.0015 0.0000000025409 0.0000000025409
Schistosoma mansoni ap endonuclease 0.0019 0.0002 0.0002
Trypanosoma brucei DNA polymerase kappa, putative 0.0099 0.0061 0.0082
Trypanosoma cruzi DNA polymerase kappa, putative 0.0099 0.0061 0.0082
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0002 0.003
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0158 0.0105 0.0105
Schistosoma mansoni short chain dehydrogenase 0.002 0.0003 0.0003
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0003 0.0003
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0019 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0033 0.0013 0.0013
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0011 0.0014
Trichomonas vaginalis short-chain dehydrogenase, putative 0.002 0.0003 0.0064
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0019 0.0003 0.0003
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0305 0.0213 0.5289
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0158 0.0105 0.0105
Brugia malayi regulator of G-protein signaling rgs-7 0.002 0.0004 0.0004
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0003 0.0003
Mycobacterium ulcerans hypothetical protein 0.0025 0.0007 0.0125
Echinococcus granulosus orexin receptor type 2 0.0019 0.0003 0.0003
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0051 0.0026 0.0026
Brugia malayi nuclear hormone receptor family member nhr-6 0.0075 0.0044 0.0044
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0038 0.0051
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0019 0.0003 0.0003
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0267 0.0186 0.461
Trypanosoma brucei DNA polymerase kappa, putative 0.0099 0.0061 0.0082
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0182 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Trypanosoma brucei DNA polymerase kappa, putative 0.0099 0.0061 0.0082
Toxoplasma gondii ABC1 family protein 0.0033 0.0013 0.0012
Brugia malayi hypothetical protein 0.1004 0.0728 0.0728
Echinococcus granulosus g-protein coupled receptor 0.0019 0.0003 0.0003
Entamoeba histolytica tumor susceptibility gene 101 protein, putative 0.0047 0.0023 0.05
Mycobacterium ulcerans monooxygenase 0.0026 0.0008 0.0141
Schistosoma mansoni cathepsin F (C01 family) 0.0018 0.0002 0.0002
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0095 0.0059 0.0057
Brugia malayi Cathepsin L-like precursor 0.0018 0.0002 0.0002
Schistosoma mansoni carbonyl reductase 0.002 0.0003 0.0003
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0003 0.0024
Echinococcus granulosus axis inhibition protein axin 0.002 0.0004 0.0004
Loa Loa (eye worm) oxidoreductase 0.002 0.0003 0.0003
Onchocerca volvulus Segment polarity protein dishevelled homolog 0.0017 0.0002 0.0033
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0015 0.0334
Leishmania major hypothetical protein, conserved 0.002 0.0003 0.0004
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0114 0.0073 0.1664
Echinococcus granulosus dna polymerase eta 0.0123 0.0079 0.0079
Leishmania major DNA topoisomerase 1A 0.0252 0.0175 0.0234
Mycobacterium tuberculosis UDP-galactopyranose mutase Glf (UDP-GALP mutase) (NAD+-flavin adenine dinucleotide-requiring enzyme) 0.0561 0.0402 1
Trichomonas vaginalis glucosylceramidase, putative 0.0272 0.0189 0.4424
Entamoeba histolytica hypothetical protein 0.029 0.0202 0.4708
Onchocerca volvulus 0.0018 0.0002 0.0035
Loa Loa (eye worm) hypothetical protein 0.002 0.0004 0.0004
Echinococcus granulosus importin subunit beta 1 0.003 0.0011 0.0011
Trypanosoma brucei beta-ketoacyl-ACP reductase 2 0.002 0.0003 0.0004
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.002 0.0003 0.0034
Plasmodium vivax hypothetical protein, conserved 0.0028 0.001 0.0008
Loa Loa (eye worm) hypothetical protein 0.0158 0.0105 0.0105
Leishmania major protein kinase, putative 0.0085 0.0051 0.0068
Loa Loa (eye worm) hypothetical protein 0.0028 0.001 0.001
Plasmodium vivax DNA repair protein REV1, putative 0.0022 0.0005 0.0003
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0018 0.0002 0.0044
Leishmania major quinonoid dihydropteridine reductase 0.002 0.0003 0.0004
Echinococcus granulosus inositol monophosphatase 1 0.0114 0.0073 0.0073
Loa Loa (eye worm) hypothetical protein 0.0084 0.005 0.005
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0047 0.0024 0.0024
Toxoplasma gondii histone lysine methyltransferase SET1 0.0126 0.0081 0.008
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.012 0.2808
Brugia malayi Globin family protein 0.0026 0.0008 0.0008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0002 0.003
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Echinococcus multilocularis Ankyrin 0.0015 0.0000094892 0.0000094892
Trypanosoma cruzi cruzipain precursor, putative 0.0067 0.0038 0.0051
Plasmodium falciparum ataxin-2 like protein, putative 0.0128 0.0083 0.0081
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0038 0.005
Entamoeba histolytica serine/threonine protein kinase, putative 0.019 0.0129 0.2986
Brugia malayi beta-lactamase family protein 0.0033 0.0013 0.0013
Schistosoma mansoni opsin-like receptor 0.0019 0.0003 0.0003
Trypanosoma brucei membrane transporter protein, putative 0.0067 0.0038 0.0051
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0006 0.0139
Schistosoma mansoni steroid hormone receptor ad4bp 0.0158 0.0105 0.0105
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0084 0.005 0.005
Echinococcus multilocularis pyruvate kinase 0.0137 0.009 0.009
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0038 0.0038
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0063 0.0035 0.0035
Leishmania major hypothetical protein, conserved 0.002 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0038 0.0017 0.0022
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0072 0.0042 0.0042
Echinococcus multilocularis regulator of G protein signaling 7 0.0038 0.0017 0.0017
Trichomonas vaginalis glucosylceramidase, putative 0.0272 0.0189 0.4424
Trypanosoma brucei ATP-binding cassette protein, putative 0.002 0.0003 0.0004
Loa Loa (eye worm) oxidoreductase 0.002 0.0003 0.0003
Echinococcus multilocularis survival motor neuron protein 1 0.1429 0.1041 0.1041
Brugia malayi hypothetical protein 0.0018 0.0002 0.0002
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0046 0.0023 0.0023
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.002 0.0003 0.0004
Schistosoma mansoni carbonyl reductase 0.002 0.0003 0.0003
Echinococcus granulosus Pleckstrin G protein interacting region 0.0017 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0172 0.0115 0.0115
Leishmania major cathepsin L-like protease 0.0067 0.0038 0.0051
Schistosoma mansoni fyve finger-containing phosphoinositide kinase fyv1 0.0017 0.0002 0.0002
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0003 0.0004
Echinococcus multilocularis dna polymerase eta 0.0123 0.0079 0.0079
Echinococcus multilocularis isocitrate dehydrogenase 0.0095 0.0059 0.0059
Onchocerca volvulus 0.0075 0.0044 0.0835
Brugia malayi GnHR receptor homolog 0.0019 0.0003 0.0003
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0047 0.0024 0.0024
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0158 0.0105 0.0105
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0095 0.0059 0.0078
Schistosoma mansoni inositol monophosphatase 0.0114 0.0073 0.0073
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.002 0.0003 0.0002
Giardia lamblia Histone acetyltransferase GCN5 0.0159 0.0106 0.2433
Echinococcus multilocularis dro:myosuppressin receptor 0.0019 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.002 0.0003 0.0003
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0114 0.0073 0.3444
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0011 0.0014
Echinococcus multilocularis allatostatin A receptor 0.0019 0.0003 0.0003
Trypanosoma brucei DNA topoisomerase type IB small subunit 0.4945 0.363 0.4886
Echinococcus granulosus transcription factor Dp 1 0.0038 0.0017 0.0017
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0036 0.0016 0.0016
Echinococcus multilocularis somatostatin receptor 0.0019 0.0003 0.0003
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.002 0.0003 0.0024
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0003 0.0003
Loa Loa (eye worm) globin family protein 0.0026 0.0008 0.0008
Schistosoma mansoni steroid dehydrogenase 0.002 0.0003 0.0003
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0015 0.0000000025409 0.0000000025409
Onchocerca volvulus 0.002 0.0003 0.0063
Loa Loa (eye worm) PXA domain-containing protein 0.002 0.0004 0.0004
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0177 0.0119 0.0119
Trypanosoma brucei pyruvate kinase 1, putative 0.0267 0.0186 0.0249
Brugia malayi Cathepsin L-like precursor 0.0018 0.0002 0.0002
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0018 0.0002 0.0033
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0009 0.0209
Brugia malayi Pyruvate kinase, M2 isozyme 0.0267 0.0186 0.0186
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0018 0.0002 0.0033
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0089 0.0054 0.0054
Loa Loa (eye worm) beta-lactamase 0.0033 0.0013 0.0013
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0019 0.0003 0.0003
Schistosoma mansoni short chain dehydrogenase 0.002 0.0003 0.0003
Echinococcus granulosus intermediate filament protein 0.0055 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0033 0.0013 0.0013
Mycobacterium tuberculosis Probable oxidoreductase 0.002 0.0003 0.0057
Mycobacterium tuberculosis Probable short-chain type oxidoreductase 0.002 0.0003 0.0057
Onchocerca volvulus 0.0017 0.0002 0.0033
Brugia malayi hypothetical protein 0.0019 0.0003 0.0003
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0016 0.0016
Loa Loa (eye worm) cytochrome P450 family protein 0.0045 0.0022 0.0022
Mycobacterium ulcerans lipase LipD 0.0033 0.0013 0.0277
Onchocerca volvulus Globin homolog 0.0026 0.0008 0.0152
Trypanosoma brucei PAB1-binding protein , putative 0.0128 0.0083 0.0111
Onchocerca volvulus 0.0018 0.0002 0.0035
Plasmodium falciparum metacaspase 1 0.0089 0.0054 0.0052
Trypanosoma brucei DNA polymerase kappa, putative 0.0099 0.0061 0.0082
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0046 0.0023 0.003
Trypanosoma cruzi PAB1-binding protein , putative 0.0128 0.0083 0.0111
Echinococcus granulosus cytochrome P450 2K1 0.0018 0.0002 0.0002
Giardia lamblia Reductase, putative 0.002 0.0003 0.0018
Brugia malayi Pre-SET motif family protein 0.0063 0.0035 0.0035
Echinococcus granulosus neuropeptide receptor 0.0019 0.0003 0.0003
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.006 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0009
Echinococcus multilocularis carbonyl reductase 1 0.002 0.0003 0.0003
Loa Loa (eye worm) oxidoreductase 0.002 0.0003 0.0003
Echinococcus granulosus 7TM GPCR rhodopsin 0.0019 0.0003 0.0003
Onchocerca volvulus Protein cycle homolog 0.0018 0.0002 0.0042
Loa Loa (eye worm) hypothetical protein 0.0158 0.0105 0.0105
Schistosoma mansoni hypothetical protein 0.0315 0.0221 0.0221
Brugia malayi RE15519p 0.0019 0.0003 0.0003
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0095 0.0059 0.0059
Brugia malayi MH1 domain containing protein 0.0023 0.0005 0.0005
Mycobacterium tuberculosis Probable oxidoreductase 0.002 0.0003 0.0057
Schistosoma mansoni carbonyl reductase 0.002 0.0003 0.0003
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0022 0.0005 0.0055
Loa Loa (eye worm) TAR-binding protein 0.0067 0.0038 0.0038
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0061 0.0034 0.0045
Loa Loa (eye worm) histone methyltransferase 0.002 0.0004 0.0004
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0045 0.0022 0.0022
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0158 0.0105 0.0105
Onchocerca volvulus 0.0019 0.0003 0.0053
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0017 0.0001 0.0011
Toxoplasma gondii aldehyde dehydrogenase 0.0185 0.0125 0.0123
Trichomonas vaginalis CAMK family protein kinase 0.019 0.0129 0.3007
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.012 0.2808
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0019 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.002 0.0003 0.0003
Toxoplasma gondii Alpha-galactosidase 0.003 0.0011 0.0009
Entamoeba histolytica hypothetical protein, conserved 0.002 0.0003 0.0034
Trichomonas vaginalis ran, putative 0.0022 0.0005 0.0101
Brugia malayi bHLH-PAS transcription factor 0.0216 0.0148 0.0148
Mycobacterium ulcerans pyruvate kinase 0.0267 0.0186 0.4592
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0025 0.0007 0.0009
Toxoplasma gondii isocitrate dehydrogenase 0.0095 0.0059 0.0057
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Echinococcus granulosus cathepsin l cysteine peptidase 0.0018 0.0002 0.0002
Echinococcus granulosus SAM and MBT domain containing protein 0.0053 0.0028 0.0028
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0011 0.0257
Leishmania major glycosyl hydrolase-like protein 0.0018 0.0002 0.0002
Echinococcus multilocularis sex peptide receptor 0.0019 0.0003 0.0003
Echinococcus multilocularis beta adrenergic receptor kinase 0.0021 0.0005 0.0005
Trypanosoma brucei DNA topoisomerase III, putative 0.0259 0.018 0.0241
Echinococcus granulosus retinol dehydrogenase 11 0.002 0.0003 0.0003
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.012 0.2808
Entamoeba histolytica 3-ketodihydrosphingosine reductase protein, putative 0.002 0.0003 0.0034
Echinococcus multilocularis neutral alpha glucosidase AB 0.0048 0.0024 0.0024
Echinococcus multilocularis PHD finger protein rhinoceros 0.0028 0.001 0.001
Trichomonas vaginalis guanylate cyclase, putative 0.0084 0.005 0.1168
Echinococcus multilocularis sterol regulatory element binding protein 0.0042 0.002 0.002
Trichomonas vaginalis alpha-glucosidase, putative 0.0018 0.0002 0.0032
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0038 0.0017 0.0022
Loa Loa (eye worm) hypothetical protein 0.0158 0.0105 0.0105
Trypanosoma brucei short-chain dehydrogenase, putative 0.002 0.0003 0.0004
Brugia malayi Globin family protein 0.0026 0.0008 0.0008
Toxoplasma gondii exonuclease III APE 0.0019 0.0002 0.0001
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0058 0.0031 0.0031
Entamoeba histolytica hypothetical protein 0.029 0.0202 0.4708
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0016 0.0016
Schistosoma mansoni jumonji/arid domain-containing protein 0.0158 0.0105 0.0105
Mycobacterium tuberculosis Probable oxidoreductase 0.002 0.0003 0.0057
Brugia malayi hypothetical protein 0.0084 0.005 0.005
Echinococcus granulosus neuropeptides capa receptor 0.0019 0.0003 0.0003
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0158 0.0105 0.0105
Trichomonas vaginalis CAMK family protein kinase 0.019 0.0129 0.3007
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0139 0.0091 0.0091
Echinococcus multilocularis ecdysone induced protein 78C 0.0158 0.0105 0.0105
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0054 0.0029 0.0029
Loa Loa (eye worm) TYRA-2 protein 0.0019 0.0003 0.0003
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.002 0.0003 0.0004
Brugia malayi hypothetical protein 0.0019 0.0003 0.0003
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0003 0.0003
Brugia malayi jmjC domain containing protein 0.0158 0.0105 0.0105
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0305 0.0213 0.5304
Plasmodium vivax JmjC domain containing protein 0.0041 0.0019 0.0017
Mycobacterium tuberculosis Conserved hypothetical protein 0.0072 0.0042 0.1017
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0158 0.0105 0.0105
Brugia malayi Intermediate filament tail domain containing protein 0.0055 0.0029 0.0029
Schistosoma mansoni short-chain dehydrogenase/reductase 0.002 0.0003 0.0003
Trypanosoma brucei DNA polymerase kappa, putative 0.0056 0.003 0.004
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0053 0.0028 0.0028
Trypanosoma cruzi Vps23 core domain containing protein, putative 0.0022 0.0005 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0089 0.0054 0.1259
Echinococcus granulosus pyruvate kinase 0.0137 0.009 0.009
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0003 0.0024
Brugia malayi Flap endonuclease-1 0.0027 0.0009 0.0009
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0209 0.0143 0.0143
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0003 0.0024
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Trypanosoma cruzi metacaspase, putative 0.0089 0.0054 0.0072
Giardia lamblia DNA topoisomerase III 0.0252 0.0175 0.4054
Trypanosoma brucei DNA polymerase IV, putative 0.0092 0.0057 0.0075
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0003 0.0024
Echinococcus multilocularis nuclear receptor nhr 48 0.0075 0.0044 0.0044
Schistosoma mansoni ferritin 0.0034 0.0014 0.0014
Trichomonas vaginalis penicillin-binding protein, putative 0.0033 0.0013 0.0301
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.002 0.0003 0.0057
Schistosoma mansoni regulator of G protein signaling 0.002 0.0004 0.0004
Trypanosoma cruzi DNA topoisomerase type IB small subunit, putative 0.4945 0.363 0.4886
Loa Loa (eye worm) jmjC domain-containing protein 0.0041 0.0019 0.0019
Leishmania major DNA polymerase kappa, putative 0.0078 0.0047 0.0062
Echinococcus multilocularis apoptotic protease activating factor 1 0.0083 0.005 0.005
Leishmania major hypothetical protein, conserved 0.002 0.0003 0.0004
Onchocerca volvulus 0.002 0.0003 0.0063
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0002 0.003
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0173 0.0116 0.0115
Schistosoma mansoni adenoreceptor 0.0019 0.0003 0.0003
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0003 0.0003
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0083 0.005 0.005
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0018 0.0002 0.0002
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0002 0.0037
Loa Loa (eye worm) hypothetical protein 0.0033 0.0013 0.0013
Onchocerca volvulus 0.0019 0.0003 0.0053
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0003 0.0003
Trypanosoma brucei short-chain dehydrogenase, putative 0.002 0.0003 0.0004
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0213 0.0145 0.0145
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.0083 0.005 0.005
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0018 0.0002 0.0033
Onchocerca volvulus 0.0018 0.0002 0.0035
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0004 0.0075
Echinococcus multilocularis carbonyl reductase 1 0.002 0.0003 0.0003
Schistosoma mansoni neuropeptide receptor 0.0019 0.0003 0.0003
Mycobacterium ulcerans beta-lactamase 0.0033 0.0013 0.0277
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0019 0.0003 0.0003
Trichomonas vaginalis short-chain dehydrogenase, putative 0.002 0.0003 0.0064
Echinococcus granulosus Niemann Pick C1 protein 0.0139 0.0091 0.0091
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0003 0.0024
Schistosoma mansoni caspase-7 (C14 family) 0.0172 0.0115 0.0115
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0095 0.0059 0.0078
Schistosoma mansoni hypothetical protein 0.0017 0.0001 0.0001
Echinococcus multilocularis FTZ F1 alpha 0.0158 0.0105 0.0105
Echinococcus granulosus lysine specific demethylase 6a 0.0041 0.0019 0.0019
Onchocerca volvulus 0.0019 0.0003 0.0053
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0158 0.0105 0.0105
Trypanosoma brucei hypothetical protein, conserved 0.0022 0.0005 0.0006
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0018 0.0002 0.0033
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0084 0.005 0.0067
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0182 0.0123 0.3014
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0003 0.0024
Brugia malayi TAR-binding protein 0.0067 0.0038 0.0038
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0019 0.0003 0.0003
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0057 0.0031 0.0591
Mycobacterium ulcerans hypothetical protein 0.0022 0.0005 0.0074
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0015 0.0000000025409 0.0000000025409
Echinococcus granulosus muscleblind protein 0.061 0.0438 0.0438
Schistosoma mansoni myelin transcription factor 1 myt1 0.006 0.0033 0.0033
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0018 0.0002 0.0002
Brugia malayi DNA topoisomerase III beta-1 0.0131 0.0086 0.0086
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0339 0.0239 0.5917
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0158 0.0105 0.0105
Trypanosoma cruzi short chain dehydrogenase, putative 0.002 0.0003 0.0004
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.019 0.0129 0.0129
Schistosoma mansoni dishevelled 0.0017 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0168 0.0113 0.0113
Trypanosoma cruzi DNA topoisomerase III, putative 0.0259 0.018 0.0241
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0002 0.003
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Loa Loa (eye worm) DNA topoisomerase III 0.0259 0.018 0.018
Mycobacterium ulcerans DNA polymerase IV 0.0099 0.0061 0.1479
Schistosoma mansoni prokaryotic DNA topoisomerase 0.0131 0.0086 0.0086
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0004 0.0075
Trichomonas vaginalis guanylate cyclase, putative 0.0084 0.005 0.1168
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.029 0.0202 0.0202
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0002 0.0004
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0018 0.0002 0.0002
Brugia malayi Regulator of G protein signaling domain containing protein 0.002 0.0004 0.0004
Echinococcus multilocularis regulator of G protein signaling 3 0.002 0.0004 0.0004
Echinococcus granulosus mothers against decapentaplegic 2 0.0018 0.0002 0.0002
Loa Loa (eye worm) pyruvate kinase 0.0056 0.003 0.003
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.002 0.0004 0.0004
Onchocerca volvulus 0.002 0.0003 0.0063
Brugia malayi Retinol dehydrogenase 12 0.002 0.0003 0.0003
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0019 0.0003 0.0003
Loa Loa (eye worm) neuropeptide F receptor 0.0019 0.0003 0.0003
Echinococcus multilocularis transient receptor potential cation channel 0.002 0.0003 0.0003
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.002 0.0003 0.0026
Mycobacterium ulcerans ketoacyl reductase 0.002 0.0003 0.0024
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0019 0.0003 0.0003
Loa Loa (eye worm) pyruvate kinase 0.0267 0.0186 0.0186
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0015 0.0334
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0003 0.0003
Loa Loa (eye worm) DNA topoisomerase I 1.3596 1 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Treponema pallidum fructose-bisphosphate aldolase 0.0595 0.0427 1
Echinococcus granulosus biogenic amine 5HT receptor 0.0019 0.0003 0.0003
Brugia malayi Serotonin receptor 0.0019 0.0003 0.0003
Brugia malayi ecdysteroid receptor 0.0158 0.0105 0.0105
Onchocerca volvulus 0.0216 0.0148 0.2817
Plasmodium falciparum topoisomerase I 1.3596 1 1
Loa Loa (eye worm) hypothetical protein 0.0186 0.0126 0.0126
Schistosoma mansoni short chain dehydrogenase 0.002 0.0003 0.0003
Toxoplasma gondii thioredoxin reductase 0.0134 0.0087 0.0086
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0085 0.0051 0.0068
Schistosoma mansoni RAR-like nuclear receptor 0.0158 0.0105 0.0105
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0046 0.0023 0.003
Echinococcus granulosus multidrug and toxin extrusion protein 2 0.0067 0.0038 0.0038
Brugia malayi jmjC domain containing protein 0.0041 0.0019 0.0019
Echinococcus multilocularis neuropeptide receptor 0.0019 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0081 0.0048 0.0048
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0003 0.0003
Loa Loa (eye worm) cysteine protease 0.0018 0.0002 0.0002
Giardia lamblia DINP protein human, muc B family 0.0078 0.0047 0.1039
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0018 0.0002 0.0033
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0017 0.0001 0.0001
Onchocerca volvulus 0.002 0.0003 0.0063
Echinococcus multilocularis segment polarity protein dishevelled 0.0017 0.0002 0.0002
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0046 0.0023 0.0023
Trichomonas vaginalis glucosylceramidase, putative 0.0272 0.0189 0.4424
Brugia malayi tailless protein 0.0075 0.0044 0.0044
Leishmania major DNA damage repair protein, putative 0.0022 0.0005 0.0006
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0002 0.003
Echinococcus granulosus pyruvate kinase 0.0137 0.009 0.009
Echinococcus multilocularis expressed protein 0.0034 0.0014 0.0014
Mycobacterium leprae Probable DNA topoisomerase I TopA (omega-protein) (relaxing enzyme) (untwisting enzyme) (swivelase) (type I DNA topoisomerase) ( 0.0252 0.0175 0.4316
Echinococcus multilocularis geminin 0.1201 0.0873 0.0873
Echinococcus multilocularis retinol dehydrogenase 11 0.002 0.0003 0.0003
Trypanosoma brucei DNA polymerase kappa, putative 0.0099 0.0061 0.0082
Trypanosoma cruzi metacaspase, putative 0.0089 0.0054 0.0072
Schistosoma mansoni nuclear receptor 0.0075 0.0044 0.0044
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0018 0.0002 0.0032
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0102 0.0064 0.1569
Brugia malayi mothers against decapentaplegic homolog 3 0.0018 0.0002 0.0002
Brugia malayi hypothetical protein 0.0019 0.0003 0.0003
Mycobacterium ulcerans putative regulatory protein 0.0216 0.0148 0.364
Trichomonas vaginalis hypothetical protein 0.0033 0.0013 0.0301
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0004 0.0075
Brugia malayi nuclear hormone receptor 0.0158 0.0105 0.0105
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0008 0.0167
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0022 0.0005 0.0003
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0038 0.0051
Brugia malayi Cytochrome P450 family protein 0.0045 0.0022 0.0022
Trichomonas vaginalis CAMK family protein kinase 0.019 0.0129 0.3007
Echinococcus multilocularis axis inhibition protein axin 0.002 0.0004 0.0004
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0025 0.0007 0.0159
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0017 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.002 0.0003 0.0057
Brugia malayi larval opioid receptor 0.0019 0.0003 0.0003
Echinococcus multilocularis kelch ECH associated protein 1 0.0093 0.0057 0.0057
Echinococcus multilocularis ferritin 0.0034 0.0014 0.0014
Trichomonas vaginalis adenylate cyclase, putative 0.0084 0.005 0.1168
Schistosoma mansoni short chain dehydrogenase 0.002 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0038 0.0051
Leishmania major hypothetical protein, conserved 0.0128 0.0083 0.0111
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0003 0.0003
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0016 0.0001 0.0001
Toxoplasma gondii DNA topoisomerase I, putative 1.3596 1 1
Echinococcus granulosus tm gpcr rhodopsin 0.0019 0.0003 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0015 0.0334
Leishmania major cathepsin L-like protease 0.0018 0.0002 0.0002
Plasmodium falciparum ABC transporter G family member 2 0.002 0.0003 0.0002
Brugia malayi ImpB/MucB/SamB family protein 0.0123 0.0079 0.0079
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0168 0.0113 0.2604
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0095 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.002 0.0003 0.0003
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0003 0.0024
Brugia malayi hypothetical protein 0.0019 0.0003 0.0003
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0025 0.0007 0.0125
Mycobacterium tuberculosis Probable dehydrogenase 0.0305 0.0213 0.5304
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0089 0.0054 0.1259
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0003 0.0003
Trypanosoma brucei polo-like protein kinase 0.019 0.0129 0.0173
Echinococcus multilocularis neuropeptide Y receptor 0.0019 0.0003 0.0003
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0173 0.0116 0.2717
Brugia malayi hypothetical protein 0.0128 0.0083 0.0083
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.002 0.0003 0.0003
Brugia malayi ecdysone receptor 0.0075 0.0044 0.0044
Leishmania major cathepsin L-like protease 0.0018 0.0002 0.0002
Leishmania major hypothetical protein, conserved 0.0022 0.0005 0.0006
Brugia malayi hypothetical protein 0.0019 0.0003 0.0003
Echinococcus granulosus nuclear receptor nhr 48 0.0075 0.0044 0.0044
Onchocerca volvulus 0.002 0.0003 0.0063
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0017 0.0376
Entamoeba histolytica acetyltransferase, GNAT family 0.0159 0.0106 0.2445
Echinococcus granulosus caspase 2 0.0172 0.0115 0.0115
Plasmodium vivax DNA topoisomerase II, putative 0.0057 0.0031 0.0029
Echinococcus multilocularis tar DNA binding protein 0.0067 0.0038 0.0038
Schistosoma mansoni regulator of G protein signaling 0.002 0.0004 0.0004
Loa Loa (eye worm) glutathione reductase 0.0134 0.0087 0.0087
Echinococcus multilocularis mothers against decapentaplegic 2 0.0018 0.0002 0.0002
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0003 0.0003
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0066 0.0038 0.0038
Toxoplasma gondii oxidoreductase, putative 0.002 0.0003 0.0002
Trypanosoma cruzi trypanothione reductase, putative 0.0134 0.0087 0.0117
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0078 0.0046 0.0046
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0095 0.0059 0.0078
Onchocerca volvulus 0.0131 0.0086 0.1634
Loa Loa (eye worm) hypothetical protein 0.0051 0.0026 0.0026
Leishmania major pteridine reductase 1 0.002 0.0003 0.0004
Echinococcus granulosus smad 0.0041 0.0019 0.0019
Echinococcus granulosus survival motor neuron protein 1 0.1429 0.1041 0.1041
Onchocerca volvulus Alhambra homolog 0.0028 0.001 0.0186
Echinococcus multilocularis g protein coupled receptor 0.0019 0.0003 0.0003
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0124 0.008 0.008
Trypanosoma brucei beta-D-hydroxybutyrate dehydrogenase 0.002 0.0003 0.0004
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0045 0.0022 0.0022
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0038 0.0051
Schistosoma mansoni pyruvate kinase 0.0267 0.0186 0.0186
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0003 0.0004
Trypanosoma cruzi DNA polymerase eta, putative 0.0073 0.0043 0.0057
Schistosoma mansoni neuropeptide receptor 0.0019 0.0003 0.0003
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.012 0.2808
Echinococcus multilocularis Regulator of G protein signaling 20 0.002 0.0004 0.0004
Echinococcus multilocularis mothers against decapentaplegic 5 0.0041 0.0019 0.0019
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0015 0.0334
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.002 0.0003 0.0003
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0158 0.0105 0.0105
Trypanosoma cruzi hypothetical protein, conserved 0.0067 0.0038 0.0051
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0158 0.0105 0.0105
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0057 0.0031 0.0031
Echinococcus granulosus carbonyl reductase 1 0.002 0.0003 0.0003
Mycobacterium ulcerans aldehyde dehydrogenase 0.0185 0.0125 0.3076
Echinococcus multilocularis lamin 0.0055 0.0029 0.0029
Onchocerca volvulus 0.0291 0.0203 0.3881
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0038 0.005
Brugia malayi beta-lactamase 0.0033 0.0013 0.0013
Echinococcus multilocularis Niemann Pick C1 protein 0.0097 0.006 0.006
Brugia malayi Dehydrogenases, short chain protein 30 0.002 0.0003 0.0003
Giardia lamblia Kinase, PLK 0.019 0.0129 0.2975
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0018 0.0002 0.0033
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0018 0.0002 0.0032
Mycobacterium tuberculosis Probable esterase LipL 0.0033 0.0013 0.0309
Onchocerca volvulus 0.0065 0.0037 0.0703
Brugia malayi regulator of G-protein signaling egl-10 0.0038 0.0017 0.0017
Trypanosoma brucei DNA polymerase kappa, putative 0.0099 0.0061 0.0082
Mycobacterium tuberculosis Probable shortchain dehydrogenase 0.002 0.0003 0.0057
Entamoeba histolytica DNA topoisomerase II, putative 0.0057 0.0031 0.0685
Echinococcus granulosus Nuclear hormone receptor HR96 0.0075 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 0.0089 0.0054 0.0054
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0158 0.0105 0.0105
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.0058 0.1355
Trichomonas vaginalis set domain proteins, putative 0.0489 0.0349 0.8157
Onchocerca volvulus Sepiapterin reductase homolog 0.002 0.0003 0.0063
Mycobacterium tuberculosis Possible oxidoreductase 0.002 0.0003 0.0057
Leishmania major trypanothione reductase 0.0134 0.0087 0.0117
Brugia malayi Niemann-Pick C1 protein precursor 0.0097 0.006 0.006
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0051 0.0026 0.0026
Schistosoma mansoni hypothetical protein 0.0093 0.0057 0.0057
Echinococcus multilocularis neuropeptide s receptor 0.0019 0.0003 0.0003
Toxoplasma gondii DNA topoisomerase domain-containing protein 0.0174 0.0117 0.0115
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0046 0.0023 0.003
Leishmania major short chain dehydrogenase-like protein 0.002 0.0003 0.0004
Entamoeba histolytica pyruvate kinase, putative 0.0186 0.0126 0.2922
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0057 0.0031 0.0041
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0002 0.003
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.005 0.1168
Entamoeba histolytica hypothetical protein 0.0024 0.0006 0.0109
Mycobacterium tuberculosis Decaprenylphosphoryl-D-2-keto erythro pentose reductase 0.002 0.0003 0.0057
Schistosoma mansoni jumonji domain containing protein 0.0041 0.0019 0.0019
Loa Loa (eye worm) oxidoreductase 0.002 0.0003 0.0003
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0003 0.0003
Loa Loa (eye worm) neuropeptide F receptor 0.0019 0.0003 0.0003
Trypanosoma cruzi hypothetical protein, conserved 0.0048 0.0024 0.0031
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0025 0.0007 0.0125
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0034 0.0014 0.0297
Echinococcus granulosus carbonyl reductase 1 0.002 0.0003 0.0003
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0595 0.0427 1
Loa Loa (eye worm) hypothetical protein 0.0055 0.0029 0.0029
Brugia malayi Importin beta-1 subunit 0.003 0.0011 0.0011
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0046 0.0023 0.003
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0047 0.0024 0.0031
Echinococcus granulosus cathepsin l1 0.0018 0.0002 0.0002
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0025 0.0007 0.0125
Brugia malayi Cathepsin L-like precursor 0.0018 0.0002 0.0002
Echinococcus granulosus DNA topoisomerase 3 beta 1 0.0131 0.0086 0.0086
Trichomonas vaginalis alpha-glucosidase, putative 0.0048 0.0024 0.0548
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0095 0.0059 0.0078
Schistosoma mansoni apoferritin-2 0.0034 0.0014 0.0014
Plasmodium vivax ataxin-2 like protein, putative 0.0128 0.0083 0.0081
Onchocerca volvulus 0.0057 0.0031 0.0595
Leishmania major cathepsin L-like protease 0.0018 0.0002 0.0002
Plasmodium vivax pyruvate kinase, putative 0.0267 0.0186 0.0184
Loa Loa (eye worm) hypothetical protein 0.0139 0.0091 0.0091
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0075 0.0044 0.0044
Loa Loa (eye worm) transcription factor SMAD2 0.06 0.043 0.043
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0018 0.0002 0.0033
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Echinococcus granulosus kelch ECH associated protein 1 0.0093 0.0057 0.0057
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0053 0.0028 0.0531
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0029 0.001 0.0008
Mycobacterium tuberculosis Probable lipase LipE 0.0033 0.0013 0.0309
Brugia malayi MH2 domain containing protein 0.0041 0.0019 0.0019
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0003 0.0003
Leishmania major cysteine peptidase A (CPA) 0.0018 0.0002 0.0002
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0072 0.0042 0.0042
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0005 0.0005
Echinococcus multilocularis serotonin receptor 0.0019 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0003 0.0003
Schistosoma mansoni DNA topoisomerase type I 1.3596 1 1
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.002 0.0003 0.0004
Leishmania major DNA polymerase kappa, putative 0.0022 0.0005 0.0006
Brugia malayi Dopamine receptor protein 1 0.0019 0.0003 0.0003
Onchocerca volvulus Pyruvate kinase homolog 0.0267 0.0186 0.3542
Trypanosoma cruzi DNA topoisomerase IA, putative 0.0252 0.0175 0.0234
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0047 0.0024 0.0024
Leishmania major quinonoid dihydropteridine reductase 0.002 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.002 0.0004 0.0004
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0038 0.0051
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0019 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0375 0.0265 0.0265
Echinococcus granulosus ecdysone induced protein 78C 0.0158 0.0105 0.0105
Onchocerca volvulus 0.0019 0.0003 0.0053
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0158 0.0105 0.0105
Loa Loa (eye worm) hypothetical protein 0.0026 0.0008 0.0008
Schistosoma mansoni hypothetical protein 0.029 0.0202 0.0202
Schistosoma mansoni hypothetical protein 0.0326 0.0229 0.0229
Chlamydia trachomatis DNA topoisomerase I 0.0295 0.0206 1
Schistosoma mansoni thyroid hormone receptor 0.0158 0.0105 0.0105
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0019 0.0003 0.0003
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0067 0.0038 0.0038
Echinococcus granulosus pyruvate kinase 0.0267 0.0186 0.0186
Echinococcus granulosus histone lysine methyltransferase setb 0.0063 0.0035 0.0035
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0051 0.0026 0.0026
Trypanosoma brucei DNA polymerase kappa, putative 0.0049 0.0025 0.0033
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0048 0.0024 0.0548
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.002 0.0003 0.0004
Echinococcus multilocularis transcription factor Dp 1 0.0038 0.0017 0.0017
Brugia malayi hypothetical protein 0.0083 0.005 0.005
Brugia malayi photoreceptor-specific nuclear receptor 0.1112 0.0807 0.0807
Echinococcus multilocularis musashi 0.0055 0.0029 0.0029
Trypanosoma brucei oxidoreductase-like protein 0.002 0.0003 0.0004
Brugia malayi CXXC zinc finger family protein 0.0057 0.0031 0.0031
Echinococcus multilocularis transfer RNA-Lys 0.0216 0.0148 0.0148
Onchocerca volvulus 0.002 0.0003 0.0063
Trichomonas vaginalis inositol monophosphatase, putative 0.0114 0.0073 0.169
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0002 0.003
Trichomonas vaginalis glucosylceramidase, putative 0.0272 0.0189 0.4424
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.002 0.0003 0.0024
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.002 0.0003 0.0024
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0019 0.0003 0.0003
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0089 0.0054 0.1259
Mycobacterium ulcerans aldehyde dehydrogenase 0.0185 0.0125 0.3076
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0075 0.0044 0.0044
Echinococcus granulosus hypothetical protein 0.002 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0083 0.005 0.005
Echinococcus multilocularis citrate lyase subunit beta protein 0.0025 0.0007 0.0007
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0114 0.0073 0.0097
Echinococcus multilocularis thioredoxin glutathione reductase 0.0134 0.0088 0.0088
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0017 0.0376
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0084 0.005 0.1168
Trypanosoma brucei hypothetical protein, conserved 0.0218 0.0149 0.02
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0019 0.0003 0.0003
Echinococcus granulosus polycomb protein SCMH1 0.0053 0.0028 0.0028
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.002 0.0003 0.0057
Entamoeba histolytica Flap nuclease, putative 0.0027 0.0009 0.0168
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0182 0.0123 0.3038
Trypanosoma cruzi DNA damage repair protein, putative 0.0022 0.0005 0.0006
Echinococcus multilocularis regulator of G protein signaling 7 0.0038 0.0017 0.0017
Brugia malayi DNA topoisomerase III 0.0259 0.018 0.018
Echinococcus multilocularis expressed conserved protein 0.0091 0.0056 0.0056
Brugia malayi isocitrate dehydrogenase 0.0095 0.0059 0.0059
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0003 0.0003
Trypanosoma brucei 3-ketoacyl-CoA reductase, putative 0.002 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0075 0.0044 0.0044
Trypanosoma brucei short-chain dehydrogenase, putative 0.002 0.0003 0.0004
Mycobacterium ulcerans dehydrogenase 0.002 0.0003 0.0024
Schistosoma mansoni hypothetical protein 0.0067 0.0038 0.0038
Mycobacterium leprae Probable oxidoreductase 0.002 0.0003 0.0024
Loa Loa (eye worm) RNA binding protein 0.0067 0.0038 0.0038
Schistosoma mansoni flap endonuclease-1 0.0025 0.0007 0.0007
Schistosoma mansoni aryl hydrocarbon receptor nuclear translocator homolog (darnt) 0.0018 0.0002 0.0002
Trypanosoma brucei DNA polymerase kappa, putative 0.0099 0.0061 0.0082
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0019 0.0003 0.0003
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0272 0.0189 0.0189
Loa Loa (eye worm) CYP4Cod1 0.0045 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0075 0.0044 0.0044
Brugia malayi hypothetical protein 0.0026 0.0008 0.0008
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0003 0.0003
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0158 0.0105 0.0105
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0158 0.0105 0.0105
Onchocerca volvulus 0.0019 0.0003 0.0053
Echinococcus granulosus regulator of G protein signaling 3 0.002 0.0004 0.0004
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0158 0.0105 0.0105
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0033 0.0013 0.0277
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.002 0.0003 0.0024
Schistosoma mansoni cpg binding protein 0.0061 0.0034 0.0034
Echinococcus granulosus dro:myosuppressin receptor 0.0019 0.0003 0.0003
Brugia malayi pyruvate kinase 0.0056 0.003 0.003
Schistosoma mansoni tsg101-related 0.0057 0.0031 0.0031
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0046 0.0023 0.003
Wolbachia endosymbiont of Brugia malayi Short-chain alcohol dehydrogenase family enzyme 0.002 0.0003 0.0038
Plasmodium falciparum oxidoreductase, short-chain dehydrogenase family, putative 0.002 0.0003 0.0001
Trichomonas vaginalis glucosylceramidase, putative 0.0188 0.0127 0.2974
Echinococcus granulosus zinc finger protein 0.0018 0.0002 0.0002
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0158 0.0105 0.0105
Onchocerca volvulus Protein ultraspiracle homolog 0.0158 0.0105 0.2008
Echinococcus granulosus g protein coupled receptor 0.0019 0.0003 0.0003
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0595 0.0427 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0002 0.003
Mycobacterium ulcerans hypothetical protein 0.0033 0.0013 0.0277
Mycobacterium tuberculosis Conserved protein 0.0033 0.0013 0.0309
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0051 0.0026 0.0026
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.002 0.0003 0.0024
Schistosoma mansoni cytochrome P450 0.0018 0.0002 0.0002
Trichomonas vaginalis alpha-glucosidase, putative 0.0048 0.0024 0.0548
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.002 0.0004 0.0004
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0046 0.0023 0.003
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0047 0.0024 0.0024
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0041 0.0019 0.0019
Mycobacterium tuberculosis Probable reductase 0.0305 0.0213 0.5304
Echinococcus granulosus sex peptide receptor 0.0019 0.0003 0.0003
Plasmodium falciparum JmjC domain-containing protein, putative 0.0041 0.0019 0.0017
Trypanosoma cruzi PAB1-binding protein , putative 0.0128 0.0083 0.0111
Brugia malayi G-protein coupled receptor 0.0019 0.0003 0.0003
Schistosoma mansoni sex comb on midleg homolog 0.0053 0.0028 0.0028
Leishmania major dehydrogenase-like protein 0.002 0.0003 0.0004
Trypanosoma brucei DNA topoisomerase IB, large subunit 1.0106 0.743 1
Brugia malayi nuclear hormone receptor 0.0075 0.0044 0.0044
Echinococcus granulosus ATP binding cassette sub family G 0.002 0.0003 0.0003
Echinococcus granulosus beta LACTamase domain containing family member 0.0033 0.0013 0.0013
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.002 0.0003 0.0034
Schistosoma mansoni ran 0.0022 0.0005 0.0005
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0018 0.0002 0.0002
Entamoeba histolytica DNA topoisomerase III, putative 0.0252 0.0175 0.4063
Brugia malayi Cytochrome P450 family protein 0.0038 0.0017 0.0017
Schistosoma mansoni neuropeptide F-like receptor 0.0019 0.0003 0.0003
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0018 0.0002 0.0002
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0057 0.0031 0.0041
Loa Loa (eye worm) hypothetical protein 0.061 0.0438 0.0438
Echinococcus granulosus serine:threonine protein kinase PLK1 0.019 0.0129 0.0129
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.002 0.0003 0.0004
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.001 0.0008
Onchocerca volvulus Cathepsin F homolog 0.0018 0.0002 0.0035
Echinococcus granulosus peregrin 0.0043 0.002 0.002
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0173 0.0116 0.0115
Trypanosoma brucei DNA polymerase kappa, putative 0.0056 0.003 0.004
Loa Loa (eye worm) hypothetical protein 0.061 0.0438 0.0438
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0022 0.0005 0.0003
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0075 0.0044 0.0044
Brugia malayi Cytochrome P450 family protein 0.0018 0.0002 0.0002
Trichomonas vaginalis bromodomain-containing protein, putative 0.0173 0.0116 0.2717
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0034 0.0014 0.0574
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0595 0.0427 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Schistosoma mansoni neuropeptide f receptor 76f 0.0019 0.0003 0.0003
Onchocerca volvulus 0.0019 0.0003 0.0053
Brugia malayi Muscleblind-like protein 0.061 0.0438 0.0438
Echinococcus granulosus DNA topoisomerase 1 1.3596 1 1
Plasmodium vivax hypothetical protein, conserved 0.0089 0.0054 0.0052
Mycobacterium tuberculosis Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1 0.002 0.0003 0.0057
Brugia malayi pyruvate kinase, muscle isozyme 0.0056 0.003 0.003
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0006 0.0008
Onchocerca volvulus 0.0019 0.0003 0.0053
Loa Loa (eye worm) cytochrome P450 0.0018 0.0002 0.0002
Echinococcus multilocularis flap endonuclease 1 0.0027 0.0009 0.0009
Schistosoma mansoni cathepsin F (C01 family) 0.0018 0.0002 0.0002
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0158 0.0105 0.0105
Mycobacterium tuberculosis Possible fatty acyl-CoA reductase 0.002 0.0003 0.0057
Schistosoma mansoni phosphatidylserine receptor 0.0041 0.0019 0.0019
Toxoplasma gondii ATP-binding cassette G family transporter ABCG84 0.002 0.0003 0.0002
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0057 0.0031 0.0031
Echinococcus granulosus lamin 0.0055 0.0029 0.0029
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.002 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0128 0.0083 0.0083
Trypanosoma cruzi hypothetical protein, conserved 0.0218 0.0149 0.02
Schistosoma mansoni hypothetical protein 0.1201 0.0873 0.0873
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0003 0.0002
Echinococcus multilocularis beta LACTamase domain containing family member 0.0033 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0075 0.0044 0.0044
Trypanosoma brucei unspecified product 0.005 0.0025 0.0033
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0209 0.0143 0.0143
Trypanosoma brucei metacaspase MCA2 0.0089 0.0054 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.005 0.1168
Plasmodium falciparum importin beta, putative 0.003 0.0011 0.0009
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0018 0.0002 0.0033
Onchocerca volvulus 0.0026 0.0008 0.0152
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0003 0.0003
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0066 0.0038 0.0038
Echinococcus granulosus Smad4 0.0041 0.0019 0.0019
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0005 0.0006
Leishmania major hypothetical protein, conserved 0.0067 0.0038 0.0051
Onchocerca volvulus Glucosylceramidase homolog 0.0179 0.012 0.2296
Echinococcus granulosus PHD finger protein rhinoceros 0.0028 0.001 0.001
Plasmodium vivax SET domain protein, putative 0.0063 0.0035 0.0033
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.002 0.0003 0.0024
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0019 0.0003 0.0003
Mycobacterium ulcerans DNA gyrase subunit B 0.0057 0.0031 0.0718
Loa Loa (eye worm) phosphatidylinositol 3 0.0016 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0027 0.0008 0.0008
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0041 0.0019 0.0025
Loa Loa (eye worm) hypothetical protein 0.002 0.0003 0.0003
Trichomonas vaginalis CAMK family protein kinase 0.019 0.0129 0.3007
Brugia malayi Nuclear hormone receptor E75 0.0075 0.0044 0.0044
Onchocerca volvulus Huntingtin homolog 0.0375 0.0265 0.5051
Leishmania major cathepsin L-like protease 0.0018 0.0002 0.0002
Echinococcus multilocularis neuropeptides capa receptor 0.0019 0.0003 0.0003
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0046 0.0023 0.0021
Trichomonas vaginalis short-chain dehydrogenase, putative 0.002 0.0003 0.0064
Brugia malayi cytoplasmic intermediate filament protein 0.0029 0.0011 0.0011
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0046 0.0023 0.003
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0059 0.0032 0.0032
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0085 0.0051 0.0068
Schistosoma mansoni jumonji domain containing protein 0.0194 0.0132 0.0132
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0047 0.0024 0.0031
Echinococcus granulosus tachykinin peptides receptor 99D 0.0019 0.0003 0.0003
Schistosoma mansoni cpg binding protein 0.0061 0.0034 0.0034
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0182 0.0123 0.0123
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0019 0.0003 0.0003
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0213 0.0146 0.3611
Trypanosoma cruzi quinonoid dihydropteridine reductase, putative 0.002 0.0003 0.0004
Mycobacterium tuberculosis Probable oxidoreductase 0.002 0.0003 0.0057
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0305 0.0213 0.5304
Echinococcus multilocularis fmrfamide receptor 0.0019 0.0003 0.0003
Schistosoma mansoni DNA polymerase eta 0.0123 0.0079 0.0079
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0339 0.0239 0.593
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0048 0.0024 0.0024
Loa Loa (eye worm) thioredoxin reductase 0.0134 0.0087 0.0087
Echinococcus granulosus fmrfamide receptor 0.0019 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0063 0.0035 0.0035
Trichomonas vaginalis D-aminoacylase, putative 0.0033 0.0013 0.0301
Schistosoma mansoni alpha-glucosidase 0.0126 0.0081 0.0081
Echinococcus multilocularis DNA topoisomerase 1 1.3596 1 1
Schistosoma mansoni ferritin light chain 0.0034 0.0014 0.0014
Mycobacterium ulcerans oxidoreductase 0.002 0.0003 0.0024
Brugia malayi MH1 domain containing protein 0.0041 0.0019 0.0019
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0025 0.0007 0.0009
Echinococcus granulosus pyruvate kinase 0.0267 0.0186 0.0186
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0033 0.0013 0.0013
Mycobacterium leprae Probable pyruvate kinase PykA 0.0267 0.0186 0.4592
Brugia malayi dehydrogenases, short chain protein 2 0.002 0.0003 0.0003
Onchocerca volvulus 0.002 0.0003 0.0063
Echinococcus multilocularis Pleckstrin G protein, interacting region 0.0017 0.0002 0.0002
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0315 0.0221 0.0221
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0097 0.006 0.1375
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.001 0.0214
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0027 0.0009 0.0011
Brugia malayi N-terminal motif family protein 0.0355 0.025 0.025
Schistosoma mansoni bromodomain containing protein 0.0018 0.0002 0.0002
Echinococcus granulosus single minded 2 0.0216 0.0148 0.0148
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0003 0.0024
Loa Loa (eye worm) oxidoreductase 0.002 0.0003 0.0003
Trypanosoma cruzi metacaspase 5, putative 0.0089 0.0054 0.0072
Brugia malayi Bromodomain containing protein 0.0043 0.002 0.002
Onchocerca volvulus 0.002 0.0003 0.0063
Loa Loa (eye worm) hypothetical protein 0.002 0.0003 0.0003
Schistosoma mansoni short chain dehydrogenase 0.002 0.0003 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0024 0.0543
Schistosoma mansoni hypothetical protein 0.0019 0.0003 0.0003
Echinococcus multilocularis JmjC domain containing protein 4 0.0041 0.0019 0.0019
Echinococcus granulosus segment polarity protein dishevelled 0.0017 0.0002 0.0002
Entamoeba histolytica hypothetical protein 0.029 0.0202 0.4708
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0018 0.0002 0.0002
Trichomonas vaginalis esterase, putative 0.0033 0.0013 0.0301
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0017 0.0376
Trypanosoma cruzi DNA polymerase eta, putative 0.0123 0.0079 0.0106
Leishmania major hypothetical protein, conserved 0.0033 0.0013 0.0017
Schistosoma mansoni steroid dehydrogenase 0.002 0.0003 0.0003
Brugia malayi Regulator of G protein signaling domain containing protein 0.002 0.0004 0.0004
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0018 0.0002 0.0033
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0017 0.0002 0.0002
Brugia malayi mbt repeat family protein 0.0053 0.0028 0.0028
Schistosoma mansoni axis inhibition protein axin 0.002 0.0004 0.0004
Schistosoma mansoni ferritin 0.0034 0.0014 0.0014
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0008 0.0167
Echinococcus multilocularis lysine specific demethylase 5A 0.0155 0.0103 0.0103
Echinococcus multilocularis DNA topoisomerase 3 beta 1 0.0131 0.0086 0.0086
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0036 0.0016 0.031
Loa Loa (eye worm) MH2 domain-containing protein 0.0018 0.0002 0.0002
Mycobacterium leprae Probable lipase LipE 0.0033 0.0013 0.0277
Echinococcus multilocularis carbonyl reductase 1 0.002 0.0003 0.0003
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0002 0.003
Schistosoma mansoni smad1 5 8 and 0.0041 0.0019 0.0019
Schistosoma mansoni hypothetical protein 0.0019 0.0003 0.0003
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0046 0.0023 0.003
Plasmodium vivax topoisomerase I, putative 1.3596 1 1
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0089 0.0054 0.0054
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0003 0.0003
Onchocerca volvulus 0.0055 0.0029 0.0559
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Brugia malayi intermediate filament protein 0.0055 0.0029 0.0029
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0047 0.0024 0.0031
Loa Loa (eye worm) hypothetical protein 0.0375 0.0265 0.0265
Mycobacterium leprae Possible short-chain dehydrogenase EphD 0.002 0.0003 0.0024
Schistosoma mansoni serine/threonine protein kinase 0.0177 0.0119 0.0119
Brugia malayi hypothetical protein 0.0026 0.0008 0.0008
Schistosoma mansoni amine GPCR 0.0019 0.0003 0.0003
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0038 0.005
Loa Loa (eye worm) hypothetical protein 0.0033 0.0013 0.0013
Schistosoma mansoni steroid dehydrogenase 0.002 0.0003 0.0003
Brugia malayi nuclear receptor NHR-88 0.0075 0.0044 0.0044
Loa Loa (eye worm) RGS-3 protein 0.002 0.0004 0.0004
Loa Loa (eye worm) oxidoreductase 0.002 0.0003 0.0003
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0002 0.003
Echinococcus granulosus phd:f box containing protein 0.0041 0.0019 0.0019
Schistosoma mansoni myoglobin 1 0.0026 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Brugia malayi sulfakinin receptor protein 0.0019 0.0003 0.0003
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0063 0.0035 0.0033
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.002 0.0003 0.0003
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.002 0.0003 0.0024
Schistosoma mansoni alpha-1 adrenergic receptor 0.0019 0.0003 0.0003
Brugia malayi RNA binding protein 0.0067 0.0038 0.0038
Trichomonas vaginalis prokaryotic DNA topoisomerase, putative 0.0252 0.0175 0.4081
Echinococcus granulosus neuropeptide receptor 0.0019 0.0003 0.0003
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0019 0.0003 0.0003
Schistosoma mansoni aldehyde dehydrogenase 0.0185 0.0125 0.0125
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0066 0.0038 0.0038
Onchocerca volvulus 0.0026 0.0008 0.0152
Echinococcus multilocularis histone acetyltransferase MYST2 0.006 0.0033 0.0033
Schistosoma mansoni alpha-glucosidase 0.0126 0.0081 0.0081
Loa Loa (eye worm) hypothetical protein 0.1004 0.0728 0.0728
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0016 0.0001 0.0001
Trichomonas vaginalis glucosylceramidase, putative 0.0188 0.0127 0.2974
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.002 0.0004 0.0075
Treponema pallidum DNA topoisomerase I (topA) 0.0295 0.0206 0.4795
Brugia malayi Nuclear hormone receptor-like 1 0.0084 0.005 0.005
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.002 0.0003 0.0003
Mycobacterium ulcerans short-chain membrane-associated dehydrogenase 0.002 0.0003 0.0024
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0003 0.0024
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.002 0.0003 0.0002
Brugia malayi Glycosyl hydrolases family 31 protein 0.0156 0.0103 0.0103
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.012 0.2808
Brugia malayi serine/threonine-protein kinase plk-2 0.019 0.0129 0.0129
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0019 0.0003 0.0003
Plasmodium vivax pyruvate kinase 2, putative 0.0137 0.009 0.0088
Brugia malayi Glycosyl hydrolases family 31 protein 0.0018 0.0002 0.0002
Plasmodium falciparum DNA topoisomerase 3, putative 0.0252 0.0175 0.0173
Loa Loa (eye worm) hypothetical protein 0.0075 0.0044 0.0044
Echinococcus multilocularis Multi antimicrobial extrusion protein MatE 0.0062 0.0034 0.0034
Mycobacterium ulcerans hypothetical protein 0.0025 0.0007 0.0125
Trypanosoma cruzi ATP-binding cassette protein, putative 0.002 0.0003 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0089 0.0054 0.1259
Plasmodium vivax thioredoxin reductase, putative 0.0134 0.0087 0.0086
Echinococcus granulosus cpg binding protein 0.0061 0.0034 0.0034
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0072 0.0042 0.0042
Echinococcus multilocularis Kelch repeat type 1 0.0093 0.0057 0.0057
Toxoplasma gondii DNA topoisomerase 2, putative 0.0057 0.0031 0.0029
Schistosoma mansoni hypothetical protein 0.0058 0.0031 0.0031
Trichomonas vaginalis flap endonuclease-1, putative 0.0027 0.0009 0.0198
Echinococcus granulosus caspase 3 0.0146 0.0096 0.0096
Echinococcus granulosus G protein coupled receptor 139 0.0019 0.0003 0.0003
Plasmodium falciparum steroid dehydrogenase, putative 0.002 0.0003 0.0001
Brugia malayi hypothetical protein 0.0075 0.0044 0.0044
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0003 0.0003
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0003 0.0002
Mycobacterium ulcerans ketoacyl reductase 0.002 0.0003 0.0024
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0158 0.0105 0.0105
Brugia malayi orphan nuclear receptor NR2E1 0.0075 0.0044 0.0044
Schistosoma mansoni ferritin 0.0034 0.0014 0.0014
Onchocerca volvulus 0.0158 0.0105 0.2008
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0114 0.0073 0.169
Giardia lamblia Short-chain dehydrogenase, putative 0.002 0.0003 0.0018
Toxoplasma gondii LsmAD domain-containing protein 0.0128 0.0083 0.0082
Echinococcus multilocularis steroid dehydrogenase 0.002 0.0003 0.0003
Trichomonas vaginalis maltase-glucoamylase, putative 0.0018 0.0002 0.0032
Trypanosoma brucei DNA polymerase kappa, putative 0.0099 0.0061 0.0082
Trichomonas vaginalis alpha-glucosidase, putative 0.0048 0.0024 0.0548
Echinococcus multilocularis importin subunit beta 1 0.003 0.0011 0.0011
Trypanosoma cruzi trypanothione reductase, putative 0.0046 0.0023 0.003
Schistosoma mansoni steroid dehydrogenase 0.002 0.0003 0.0003
Brugia malayi hypothetical protein 0.002 0.0004 0.0004
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0595 0.0427 1
Echinococcus multilocularis neuropeptide Y receptor 0.0019 0.0003 0.0003
Onchocerca volvulus 0.0026 0.0008 0.0152
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.029 0.0202 0.0202
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0003 0.0024
Trypanosoma cruzi short-chain dehydrogenase, putative 0.002 0.0003 0.0004
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0018 0.0002 0.0033
Onchocerca volvulus 0.0075 0.0044 0.0835
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0006 0.0139
Brugia malayi hypothetical protein 0.0017 0.0002 0.0002
Loa Loa (eye worm) melatonin receptor type 1A 0.0019 0.0003 0.0003
Echinococcus multilocularis 0.0018 0.0002 0.0002
Brugia malayi Inositol-1 0.0114 0.0073 0.0073
Leishmania major DNA polymerase eta, putative 0.0123 0.0079 0.0106
Echinococcus multilocularis neuropeptide receptor 0.0019 0.0003 0.0003
Leishmania major alpha glucosidase II subunit, putative 0.0048 0.0024 0.0031
Trypanosoma brucei DNA polymerase kappa, putative 0.0056 0.003 0.004
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0019 0.0003 0.0003
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0046 0.0023 0.003
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0022 0.0005 0.0006
Loa Loa (eye worm) oxidoreductase 0.002 0.0003 0.0003
Echinococcus granulosus regulator of G protein signaling 7 0.0038 0.0017 0.0017
Brugia malayi Cathepsin L-like precursor 0.0018 0.0002 0.0002
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0089 0.0054 0.1259
Echinococcus multilocularis cathepsin L cysteine protease 0.0018 0.0002 0.0002
Trypanosoma cruzi hypothetical protein, conserved 0.0048 0.0024 0.0031
Mycobacterium ulcerans short-chain type oxidoreductase 0.002 0.0003 0.0024
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.331 0.2426 0.2426
Loa Loa (eye worm) hypothetical protein 0.002 0.0003 0.0003
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 1 homolog 0.002 0.0003 0.0063
Brugia malayi CHE-14 protein 0.0042 0.002 0.002
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0004 0.0075
Brugia malayi hypothetical protein 0.0083 0.005 0.005
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0185 0.0125 0.3098
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0016 0.0016
Brugia malayi hypothetical protein 0.0026 0.0008 0.0008
Loa Loa (eye worm) steroid hormone receptor 0.0158 0.0105 0.0105
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0046 0.0023 0.0023
Brugia malayi Cathepsin L-like precursor 0.0018 0.0002 0.0002
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0002 0.003
Brugia malayi nuclear hormone receptor family member odr-7 0.0075 0.0044 0.0044
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0182 0.0123 0.0164
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0018 0.0002 0.0033
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0002 0.003
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0002 0.0003
Trichomonas vaginalis sucrase-isomaltase, putative 0.0048 0.0024 0.0548
Schistosoma mansoni ap endonuclease 0.0019 0.0002 0.0002
Echinococcus multilocularis kelch ECH associated protein 1 0.0093 0.0057 0.0057
Brugia malayi Serotonin receptor 0.0019 0.0003 0.0003
Brugia malayi jmjC domain containing protein 0.0041 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0075 0.0044 0.0044
Trichomonas vaginalis steroid dehydrogenase, putative 0.002 0.0003 0.0064
Mycobacterium ulcerans short-chain dehydrogenase 0.002 0.0003 0.0024
Brugia malayi MH1 domain containing protein 0.0041 0.0019 0.0019
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0075 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 0.0355 0.025 0.025
Brugia malayi hypothetical protein 0.0017 0.0002 0.0002
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0018 0.0002 0.0033
Schistosoma mansoni biogenic amine (5HT) receptor 0.0019 0.0003 0.0003
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0017 0.0002 0.0002
Plasmodium falciparum pyruvate kinase 2 0.0137 0.009 0.0088
Brugia malayi Nuclear hormone receptor-like 1 0.0158 0.0105 0.0105
Onchocerca volvulus 0.0033 0.0013 0.0255
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0158 0.0105 0.0105
Schistosoma mansoni ankyrin 23/unc44 0.0015 0.0000000025409 0.0000000025409
Loa Loa (eye worm) hypothetical protein 0.0033 0.0013 0.0013
Onchocerca volvulus 0.0019 0.0003 0.0053
Brugia malayi hypothetical protein 0.0026 0.0008 0.0008
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0035 0.0035
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0003 0.0024
Trichomonas vaginalis D-aminoacylase, putative 0.0033 0.0013 0.0301
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0158 0.0105 0.0105
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0097 0.006 0.006
Trypanosoma cruzi hypothetical protein, conserved 0.0218 0.0149 0.02
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0003 0.0024
Trypanosoma brucei pyruvate kinase 1 0.0267 0.0186 0.0249
Loa Loa (eye worm) pyruvate kinase-PB 0.0186 0.0126 0.0126
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Mycobacterium tuberculosis Probable oxidoreductase 0.0339 0.0239 0.593
Schistosoma mansoni short chain dehydrogenase 0.002 0.0003 0.0003
Toxoplasma gondii isocitrate dehydrogenase 0.0095 0.0059 0.0057
Schistosoma mansoni short chain dehydrogenase 0.002 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0158 0.0105 0.0105
Echinococcus multilocularis aryl hydrocarbon receptor 0.0102 0.0064 0.0064
Loa Loa (eye worm) DIX domain-containing protein 0.0017 0.0002 0.0002
Schistosoma mansoni aldehyde dehydrogenase 0.0185 0.0125 0.0125
Trypanosoma cruzi hypothetical protein, conserved 0.0067 0.0038 0.0051
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0018 0.0002 0.0002
Entamoeba histolytica DNA topoisomerase III, putative 0.0131 0.0086 0.197
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0075 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Leishmania major DNA topoisomerase IB, large subunit 1.0106 0.743 1
Schistosoma mansoni retinal dehydrogenase 0.002 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0158 0.0105 0.0105
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0595 0.0427 1
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0003 0.0024
Trypanosoma brucei MATE efflux family protein, putative 0.0067 0.0038 0.0051
Loa Loa (eye worm) mbt repeat family protein 0.0053 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0055 0.0029 0.0029
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.002 0.0003 0.0063
Schistosoma mansoni terminal deoxycytidyl transferase 0.0072 0.0042 0.0042
Schistosoma mansoni pyruvate kinase 0.0267 0.0186 0.0186
Mycobacterium tuberculosis Conserved protein 0.0025 0.0007 0.0157
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.002 0.0003 0.0057
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0084 0.005 0.005
Echinococcus granulosus histone acetyltransferase MYST2 0.006 0.0033 0.0033
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0003 0.0024
Plasmodium vivax hypothetical protein, conserved 0.002 0.0003 0.0001
Schistosoma mansoni steroid dehydrogenase 0.002 0.0003 0.0003
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0019 0.0003 0.0003
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0099 0.0061 0.1426
Schistosoma mansoni bromodomain containing protein 0.0018 0.0002 0.0002
Schistosoma mansoni microtubule-associated protein tau 0.1406 0.1024 0.1024
Schistosoma mansoni pyruvate kinase 0.0137 0.009 0.009
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0003 0.0003
Plasmodium falciparum metacaspase-like protein 0.0089 0.0054 0.0052
Echinococcus granulosus somatostatin receptor 0.0019 0.0003 0.0003
Echinococcus granulosus sterol regulatory element binding protein 0.0042 0.002 0.002
Brugia malayi AKH receptor 0.0019 0.0003 0.0003
Echinococcus granulosus lysosomal alpha glucosidase 0.0156 0.0103 0.0103
Brugia malayi hypothetical protein 0.0019 0.0003 0.0003
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.002 0.0003 0.0057
Echinococcus granulosus dnaJ subfamily B 0.0819 0.0592 0.0592
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.002 0.0003 0.0024
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0019 0.0003 0.0003
Echinococcus granulosus neuropeptide Y receptor 0.0019 0.0003 0.0003
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0185 0.0125 0.0125
Echinococcus granulosus tar DNA binding protein 0.0067 0.0038 0.0038
Echinococcus granulosus dna polymerase kappa 0.0099 0.0061 0.0061
Brugia malayi putative neuropeptide receptor NPR1 0.0019 0.0003 0.0003
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.002 0.0003 0.0004
Leishmania major GTP-binding protein, putative 0.0022 0.0005 0.0006
Onchocerca volvulus 0.002 0.0003 0.0063
Echinococcus multilocularis neuropeptides capa receptor 0.0019 0.0003 0.0003
Schistosoma mansoni cpg binding protein 0.0057 0.0031 0.0031
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0028 0.001 0.001
Echinococcus granulosus DNA topoisomerase 3 alpha 0.0259 0.018 0.018
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0038 0.0051
Echinococcus granulosus pyruvate kinase 0.0137 0.009 0.009
Echinococcus multilocularis tumor susceptibility gene 101 protein 0.0068 0.0039 0.0039
Echinococcus multilocularis caspase 2 0.0172 0.0115 0.0115
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0114 0.0073 0.1761
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0075 0.0044 0.0044
Brugia malayi jmjC domain containing protein 0.0041 0.0019 0.0019
Trichomonas vaginalis alpha-glucosidase, putative 0.0018 0.0002 0.0032
Trichomonas vaginalis ferritin, putative 0.0034 0.0014 0.032
Onchocerca volvulus 0.0083 0.005 0.0949
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0002 0.0002
Entamoeba histolytica Ran family GTPase 0.0022 0.0005 0.0071
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.002 0.0003 0.0004
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0084 0.005 0.1168
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0019 0.0003 0.0053
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.002 0.0004 0.0004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0002 0.003
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0084 0.005 0.005
Schistosoma mansoni regulator of G protein signaling 0.002 0.0004 0.0004
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0048 0.0024 0.0519
Echinococcus granulosus mothers against decapentaplegic 6 0.0018 0.0002 0.0002
Echinococcus multilocularis mothers against decapentaplegic 6 0.0018 0.0002 0.0002
Schistosoma mansoni Smad4 0.0018 0.0002 0.0002
Leishmania major quinonoid dihydropteridine reductase 0.002 0.0003 0.0004
Onchocerca volvulus Bile acid receptor homolog 0.0158 0.0105 0.2008
Onchocerca volvulus 0.0019 0.0003 0.0053
Loa Loa (eye worm) flap endonuclease-1 0.0027 0.0009 0.0009
Loa Loa (eye worm) hypoxia-induced factor 1 0.0902 0.0653 0.0653
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0003 0.0003
Onchocerca volvulus Serine\/threonine kinase homolog 0.019 0.0129 0.2458
Wolbachia endosymbiont of Brugia malayi topoisomerase IA, TopA 0.0295 0.0206 1
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0173 0.0116 0.0115
Echinococcus granulosus histone acetyltransferase KAT2B 0.0173 0.0116 0.0116
Giardia lamblia PHD finger protein 15 0.0028 0.001 0.0171
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0038 0.0038
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0048 0.0024 0.0548
Loa Loa (eye worm) hypothetical protein 0.1112 0.0807 0.0807
Loa Loa (eye worm) cytochrome P450 family protein 0.0045 0.0022 0.0022
Schistosoma mansoni nuclear receptor 0.0075 0.0044 0.0044
Trichomonas vaginalis glucosylceramidase, putative 0.0272 0.0189 0.4424
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0003 0.0003
Echinococcus multilocularis neuropeptide FF receptor 2 0.0019 0.0003 0.0003
Trichomonas vaginalis short-chain dehydrogenases/reductase, putative 0.002 0.0003 0.0064
Echinococcus granulosus Ankyrin 0.0015 0.0000094892 0.0000094892
Loa Loa (eye worm) jmjC domain-containing protein 0.0041 0.0019 0.0019
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.002 0.0003 0.0003
Schistosoma mansoni smad1 5 8 and 0.0041 0.0019 0.0019
Brugia malayi PXA domain containing protein 0.002 0.0004 0.0004
Loa Loa (eye worm) oxidoreductase 0.002 0.0003 0.0003
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0048 0.0024 0.0519
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0016 0.0354
Plasmodium falciparum thioredoxin reductase 0.0134 0.0087 0.0086
Leishmania major hypothetical protein, conserved 0.0218 0.0149 0.02
Brugia malayi hypothetical protein 0.0019 0.0003 0.0003
Trypanosoma cruzi short chain dehydrogenase, putative 0.002 0.0003 0.0004
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0084 0.005 0.005
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.002 0.0004 0.0004
Echinococcus multilocularis g-protein coupled receptor 0.0019 0.0003 0.0003
Schistosoma mansoni smad 0.0041 0.0019 0.0019
Schistosoma mansoni serine/threonine protein kinase 0.019 0.0129 0.0129
Echinococcus granulosus jumonji domain containing protein 0.0039 0.0018 0.0018
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0046 0.0023 0.003
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0057 0.0031 0.0591
Trichomonas vaginalis DNA polymerase eta, putative 0.0099 0.0061 0.1426
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0114 0.0073 0.0071
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.002 0.0003 0.0003
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0002 0.003
Loa Loa (eye worm) hypothetical protein 0.1429 0.1041 0.1041
Schistosoma mansoni short chain dehydrogenase 0.002 0.0003 0.0003
Mycobacterium ulcerans short-chain dehydrogenase 0.002 0.0003 0.0024
Leishmania major hypothetical protein, conserved 0.0067 0.0038 0.0051
Trichomonas vaginalis conserved hypothetical protein 0.0089 0.0054 0.1259
Echinococcus granulosus regulator of G protein signaling 3 0.002 0.0004 0.0004
Echinococcus multilocularis pyruvate kinase 0.0137 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0075 0.0044 0.0044
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0083 0.005 0.005
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.002 0.0004 0.0004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0008 0.0167
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0063 0.0035 0.0035
Onchocerca volvulus 0.0018 0.0002 0.0035
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.002 0.0003 0.0001
Schistosoma mansoni ABC transporter 0.0017 0.0001 0.0001
Plasmodium vivax DNA gyrase subunit B, putative 0.0057 0.0031 0.0029
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0158 0.0105 0.0105
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0019 0.0003 0.0003
Schistosoma mansoni lamin 0.0055 0.0029 0.0029
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0589 0.0423 0.0423
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0018 0.0002 0.0033
Brugia malayi Death domain containing protein 0.0015 0.0000000025409 0.0000000025409
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0003 0.0003
Brugia malayi Dopamine receptor protein 2 0.0019 0.0003 0.0003
Treponema pallidum bacterioferrin (TpF1) 0.0034 0.0014 0.0275
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.002 0.0003 0.0003
Brugia malayi Dopamine receptor 0.0019 0.0003 0.0003
Onchocerca volvulus Neuropeptide F receptor homolog 0.0019 0.0003 0.0053
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0075 0.0044 0.0044
Brugia malayi Pax transcription factor protein 2 0.0727 0.0524 0.0524
Schistosoma mansoni retinoic acid receptor RXR 0.0158 0.0105 0.0105
Schistosoma mansoni zinc finger protein 0.0075 0.0044 0.0044
Loa Loa (eye worm) intermediate filament protein 0.0055 0.0029 0.0029
Echinococcus granulosus retinol dehydrogenase 11 0.002 0.0003 0.0003
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0139 0.0091 0.2131
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0095 0.0059 0.0057
Schistosoma mansoni hypothetical protein 0.1201 0.0873 0.0873
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0182 0.0123 0.0123
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0209 0.0143 0.0143
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.002 0.0003 0.0024
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0003 0.0003
Onchocerca volvulus 0.002 0.0003 0.0063
Loa Loa (eye worm) hypothetical protein 0.0075 0.0044 0.0044
Brugia malayi dehydrogenases, short chain protein 9 0.002 0.0003 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0015 0.0334
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0038 0.0038
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0002 0.003
Brugia malayi MH2 domain containing protein 0.0041 0.0019 0.0019
Echinococcus granulosus oxidoreductase 0.002 0.0003 0.0003
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0027 0.0009 0.0011
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0018 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0026 0.0008 0.0008
Brugia malayi hypothetical protein 0.0019 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0015 0.0000094892 0.0000094892
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0018 0.0002 0.0033
Brugia malayi G-protein coupled receptor 0.0019 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0041 0.0019 0.0019
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0018 0.0002 0.003
Echinococcus granulosus peptide allatostatin:somatostatin 0.0019 0.0003 0.0003
Schistosoma mansoni short chain dehydrogenase 0.002 0.0003 0.0003
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0048 0.0024 0.0022
Loa Loa (eye worm) hypothetical protein 0.0075 0.0044 0.0044
Trypanosoma cruzi major cysteine proteinase, putative 0.0053 0.0028 0.0037
Echinococcus granulosus carbonyl reductase 1 0.002 0.0003 0.0003
Plasmodium falciparum DNA topoisomerase 2 0.0057 0.0031 0.0029
Echinococcus granulosus g protein coupled receptor 0.0019 0.0003 0.0003
Onchocerca volvulus 0.0026 0.0008 0.0152
Mycobacterium ulcerans short-chain dehydrogenase 0.002 0.0003 0.0024
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0595 0.0427 1
Onchocerca volvulus 0.0019 0.0003 0.0053
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0139 0.0091 0.0091
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0089 0.0054 0.1259
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0078 0.0047 0.0062
Onchocerca volvulus 0.002 0.0003 0.0063
Entamoeba histolytica hypothetical protein, conserved 0.002 0.0003 0.0034
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Schistosoma mansoni jumonji/arid domain-containing protein 0.0158 0.0105 0.0105
Onchocerca volvulus 0.0019 0.0003 0.0053
Trypanosoma cruzi ABC transporter, putative 0.002 0.0003 0.0004
Mycobacterium ulcerans aldehyde dehydrogenase 0.0185 0.0125 0.3076
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0084 0.005 0.1168
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0158 0.0105 0.0105
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.002 0.0003 0.0004
Leishmania major cytochrome p450-like protein 0.0018 0.0002 0.0002
Echinococcus granulosus neuropeptide receptor A26 0.0019 0.0003 0.0003
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0158 0.0105 0.0105
Trichomonas vaginalis pyruvate kinase, putative 0.0267 0.0186 0.4339
Brugia malayi GRF zinc finger family protein 0.0064 0.0036 0.0036
Toxoplasma gondii pyruvate kinase PyK1 0.0267 0.0186 0.0184
Toxoplasma gondii SWI2/SNF2-containing protein 0.0043 0.002 0.0019
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0305 0.0213 0.5304
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0003 0.0003
Mycobacterium ulcerans bacterioferritin BfrB 0.0034 0.0014 0.0297
Echinococcus multilocularis phd:f box containing protein 0.0041 0.0019 0.0019
Leishmania major cytochrome p450-like protein 0.0018 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.0019 0.0003 0.0003
Echinococcus multilocularis jumonji domain containing protein 0.0039 0.0018 0.0018
Schistosoma mansoni nuclear receptor nhr-48 0.0075 0.0044 0.0044
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0046 0.0023 0.0021
Echinococcus multilocularis serotonin receptor 0.0019 0.0003 0.0003
Brugia malayi Cell death protein 3 precursor 0.0172 0.0115 0.0115
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0085 0.0051 0.0068
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0012 0.0274
Plasmodium vivax metacaspase 1, putative 0.0089 0.0054 0.0052
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0038 0.0051
Echinococcus granulosus WW domain containing oxidoreductase 0.002 0.0003 0.0003
Leishmania major DNA polymerase eta, putative 0.0073 0.0043 0.0057
Loa Loa (eye worm) fibroinase 0.0018 0.0002 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0158 0.0105 0.0105
Trypanosoma cruzi membrane transporter protein, putative 0.0067 0.0038 0.0051
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0008 0.0167
Brugia malayi cytochrome P450 0.0018 0.0002 0.0002
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0595 0.0427 1
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0046 0.0023 0.0023
Mycobacterium tuberculosis Conserved protein 0.0033 0.0013 0.0309
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0034 0.0014 0.0014
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0022 0.0005 0.0004
Leishmania major 3-keto-dihydrosphingosine reductase 0.002 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0038 0.0017 0.0017
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0272 0.0189 0.0189
Echinococcus multilocularis polycomb protein SCMH1 0.0053 0.0028 0.0028
Schistosoma mansoni dishevelled 0.0017 0.0002 0.0002
Echinococcus granulosus aryl hydrocarbon receptor 0.0102 0.0064 0.0064
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0235 0.0162 0.0162
Loa Loa (eye worm) hypothetical protein 0.008 0.0048 0.0048
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.002 0.0003 0.0024
Echinococcus granulosus caspase 0.0235 0.0162 0.0162
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0057 0.0031 0.0031
Schistosoma mansoni amine GPCR 0.0019 0.0003 0.0003
Brugia malayi hypoxia-induced factor 1 0.0902 0.0653 0.0653
Echinococcus granulosus ubiquitin specific protease 41 0.0036 0.0016 0.0016
Schistosoma mansoni prokaryotic DNA topoisomerase 0.0302 0.0211 0.0211
Echinococcus multilocularis neuropeptide receptor A26 0.0019 0.0003 0.0003
Brugia malayi hypothetical protein 0.002 0.0003 0.0003
Onchocerca volvulus 0.0019 0.0003 0.0053
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0016 0.002
Giardia lamblia Fructose-bisphosphate aldolase 0.0595 0.0427 1
Trichomonas vaginalis conserved hypothetical protein 0.0089 0.0054 0.1259
Brugia malayi MH2 domain containing protein 0.06 0.043 0.043
Brugia malayi Glycosyl hydrolases family 31 protein 0.0048 0.0024 0.0024
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0291 0.0203 0.5042
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Giardia lamblia DNA topoisomerase II 0.0057 0.0031 0.0671
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Echinococcus granulosus tumor susceptibility gene 101 protein 0.0068 0.0039 0.0039
Brugia malayi ImpB/MucB/SamB family protein 0.0072 0.0042 0.0042
Schistosoma mansoni Smad4 0.0041 0.0019 0.0019
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0084 0.005 0.1168
Loa Loa (eye worm) pyruvate kinase 0.0267 0.0186 0.0186
Brugia malayi Nuclear hormone receptor-like 1 0.0084 0.005 0.005
Entamoeba histolytica short chain dehydrogenase family protein 0.002 0.0003 0.0034
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0057 0.0031 0.0671
Trypanosoma brucei metacaspase MCA3 0.0089 0.0054 0.0072
Brugia malayi Melatonin receptor type 1A 0.0019 0.0003 0.0003
Brugia malayi hypothetical protein 0.0075 0.0044 0.0044
Plasmodium falciparum pyruvate kinase 0.0267 0.0186 0.0184
Onchocerca volvulus 0.0033 0.0013 0.0255
Trypanosoma brucei DNA damage repair protein, putative 0.0022 0.0005 0.0006
Toxoplasma gondii carbonyl reductase 1, putative 0.002 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0084 0.005 0.005
Mycobacterium tuberculosis Possible iron-regulated short-chain dehydrogenase/reductase 0.002 0.0003 0.0057
Echinococcus multilocularis g protein coupled receptor 0.0019 0.0003 0.0003
Leishmania major short chain dehydrogenase/reductase, putative 0.002 0.0003 0.0004
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0003 0.0004
Trichomonas vaginalis mercuric reductase, putative 0.0046 0.0023 0.0526
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0019 0.0003 0.0003
Brugia malayi Pyruvate kinase, alpha/beta domain containing protein 0.0081 0.0048 0.0048
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0058 0.0031 0.0031
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.005 0.1168
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0021 0.0005 0.0005
Mycobacterium tuberculosis Probable dehydrogenase 0.002 0.0003 0.0057
Loa Loa (eye worm) hypothetical protein 0.0158 0.0105 0.0105
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0075 0.0044 0.0044
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0046 0.0023 0.1005
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0002
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0034 0.0014 0.0329
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0291 0.0203 0.5025
Leishmania major short chain dehydrogenase/reductase, putative 0.002 0.0003 0.0004
Loa Loa (eye worm) jmjC domain-containing protein 0.0041 0.0019 0.0019
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0024 0.0543
Echinococcus multilocularis regulator of G protein signaling 0.002 0.0004 0.0004
Echinococcus multilocularis inositol monophosphatase 1 0.0114 0.0073 0.0073
Echinococcus granulosus cathepsin L cysteine proteinase 0.0018 0.0002 0.0002
Echinococcus multilocularis lysosomal alpha glucosidase 0.0156 0.0103 0.0103
Trypanosoma cruzi cysteine peptidase, putative 0.0018 0.0002 0.0002
Loa Loa (eye worm) inositol-1 0.0114 0.0073 0.0073
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Leishmania major pyruvate kinase 0.0267 0.0186 0.0249
Trypanosoma cruzi hypothetical protein, conserved 0.0033 0.0013 0.0017
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Leishmania major quinonoid dihydropteridine reductase 0.002 0.0003 0.0004
Schistosoma mansoni steroid dehydrogenase 0.002 0.0003 0.0003
Giardia lamblia NADH oxidase lateral transfer candidate 0.0046 0.0023 0.0482
Brugia malayi Protein kinase domain containing protein 0.0177 0.0119 0.0119
Schistosoma mansoni steroid dehydrogenase 0.002 0.0003 0.0003
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.002 0.0003 0.0003
Echinococcus granulosus flap endonuclease 1 0.0027 0.0009 0.0009
Schistosoma mansoni phd/f-box containing protein 0.0041 0.0019 0.0019
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0018 0.0002 0.0033
Echinococcus multilocularis jun protein 0.0083 0.005 0.005
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0002 0.0001
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.002 0.0003 0.0024
Leishmania major hypothetical protein, conserved 0.002 0.0003 0.0004
Trypanosoma brucei hypothetical protein, conserved 0.0022 0.0005 0.0006
Brugia malayi F/Y-rich N-terminus family protein 0.0029 0.001 0.001
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.002 0.0003 0.0057
Loa Loa (eye worm) MH2 domain-containing protein 0.06 0.043 0.043
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0168 0.0113 0.2604
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0046 0.0023 0.0021
Schistosoma mansoni ferritin 0.0034 0.0014 0.0014
Schistosoma mansoni sex comb on midleg homolog 0.0053 0.0028 0.0028
Leishmania major ATP-binding cassette protein subfamily G, member 6, putative 0.002 0.0003 0.0004
Trichomonas vaginalis pyruvate kinase, putative 0.0267 0.0186 0.4339
Mycobacterium tuberculosis Probable hydrolase 0.0033 0.0013 0.0309
Echinococcus multilocularis Smad4 0.0041 0.0019 0.0019
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0019 0.0003 0.0003
Echinococcus granulosus Nuclear hormone receptor HR96 0.0075 0.0044 0.0044
Mycobacterium ulcerans esterase/lipase LipP 0.0033 0.0013 0.0277
Echinococcus multilocularis expressed protein 0.0393 0.0279 0.0279
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Echinococcus granulosus alpha 1A adrenergic receptor 0.0019 0.0003 0.0003
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0021 0.0005 0.0005
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0158 0.0105 0.0105
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.002 0.0003 0.0003
Schistosoma mansoni thyroid hormone receptor 0.0158 0.0105 0.0105
Onchocerca volvulus 0.0019 0.0003 0.0053
Echinococcus granulosus jun protein 0.0083 0.005 0.005
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0005 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0015 0.0334
Schistosoma mansoni ferritin light chain 0.0034 0.0014 0.0014
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0046 0.0023 0.0517
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0095 0.0059 0.0059
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0019 0.0003 0.0003
Echinococcus granulosus neuropeptide s receptor 0.0019 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.002 0.0004 0.0004
Onchocerca volvulus Huntingtin homolog 0.0375 0.0265 0.5051
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0182 0.0123 0.3014
Echinococcus granulosus neutral alpha glucosidase AB 0.0048 0.0024 0.0024
Echinococcus granulosus segment polarity protein dishevelled 0.0017 0.0002 0.0002
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0016 0.0354
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.012 0.2808
Loa Loa (eye worm) acetyltransferase 0.0589 0.0423 0.0423
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0003 0.0003
Brugia malayi hypothetical protein 0.0065 0.0037 0.0037
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0209 0.0143 0.0143
Brugia malayi bZIP transcription factor family protein 0.0083 0.005 0.005
Schistosoma mansoni globin X 0.0026 0.0008 0.0008
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0033 0.0013 0.0013
Trypanosoma cruzi oxidoreductase-like protein, putative 0.002 0.0003 0.0004
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0046 0.0023 0.003
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Trypanosoma cruzi DNA topoisomerase IA, putative 0.0252 0.0175 0.0234
Loa Loa (eye worm) hypothetical protein 0.0041 0.0019 0.0019
Onchocerca volvulus 0.0018 0.0002 0.0035
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0027 0.0009 0.0011
Trypanosoma brucei DNA polymerase kappa, putative 0.0099 0.0061 0.0082
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0017 0.0001 0.0001
Giardia lamblia ABC transporter 0.002 0.0003 0.0017
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0003 0.0024
Mycobacterium leprae PROBABLE SHORT CHAIN ALCOHOL DEHYDROGENASE/REDUCTASE 0.002 0.0003 0.0024
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.019 0.0129 0.0173
Trypanosoma brucei short-chain dehydrogenase, putative 0.002 0.0003 0.0004
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0075 0.0044 0.0835
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0595 0.0427 1
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0002 0.0002
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0305 0.0213 0.5304
Trichomonas vaginalis maltase-glucoamylase, putative 0.0048 0.0024 0.0548
Mycobacterium tuberculosis Probable oxidoreductase 0.002 0.0003 0.0057
Plasmodium falciparum ataxin-2 like protein, putative 0.0128 0.0083 0.0081
Schistosoma mansoni neuropeptide receptor 0.0019 0.0003 0.0003
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.002 0.0003 0.0024
Echinococcus multilocularis pyruvate kinase 0.0267 0.0186 0.0186
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0002 0.0046
Trypanosoma cruzi DNA polymerase kappa, putative 0.0099 0.0061 0.0082
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.002 0.0003 0.0057
Schistosoma mansoni short chain dehydrogenase 0.002 0.0003 0.0003
Echinococcus multilocularis 0.0405 0.0287 0.0287
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0019 0.0003 0.0003
Echinococcus multilocularis pyruvate kinase 0.0267 0.0186 0.0186
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0038 0.0051
Echinococcus multilocularis protein dispatched 1 0.0048 0.0024 0.0024
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0114 0.0073 0.0097
Schistosoma mansoni DNA topoisomerase type I 1.0106 0.743 0.743
Loa Loa (eye worm) hypothetical protein 0.006 0.0033 0.0033
Brugia malayi Probable DNA topoisomerase II 0.0057 0.0031 0.0031
Leishmania major DNA topoisomerase type IB small subunit 0.4945 0.363 0.4886
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0038 0.0051
Toxoplasma gondii cytochrome p450 superfamily protein 0.0018 0.0002 0.0001
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0005 0.0005
Schistosoma mansoni caspase-3 (C14 family) 0.0235 0.0162 0.0162
Echinococcus multilocularis caspase 0.0235 0.0162 0.0162
Loa Loa (eye worm) globin family protein 0.0026 0.0008 0.0008
Brugia malayi Pre-SET motif family protein 0.0429 0.0305 0.0305
Echinococcus multilocularis cpg binding protein 0.0061 0.0034 0.0034
Schistosoma mansoni biogenic amine receptor 0.0019 0.0003 0.0003
Brugia malayi Steroid receptor seven-up type 2 0.0158 0.0105 0.0105
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0019 0.0003 0.0003
Trypanosoma brucei membrane transporter protein, putative 0.0067 0.0038 0.0051
Trypanosoma cruzi pyruvate kinase 2, putative 0.0267 0.0186 0.0249
Onchocerca volvulus 0.0018 0.0002 0.0035
Loa Loa (eye worm) hypothetical protein 0.0068 0.0039 0.0039
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0089 0.0054 0.0053
Schistosoma mansoni hypothetical protein 0.0019 0.0003 0.0003
Brugia malayi Bromodomain containing protein 0.0018 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0185 0.0125 0.0168
Schistosoma mansoni aryl hydrocarbon receptor 0.0299 0.0209 0.0209
Brugia malayi hypothetical protein 0.029 0.0202 0.0202
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0158 0.0105 0.0105
Loa Loa (eye worm) PHD-finger family protein 0.0028 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0053 0.0028 0.0028
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0046 0.0023 0.003
Loa Loa (eye worm) CXXC zinc finger family protein 0.0057 0.0031 0.0031
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.002 0.0003 0.0034
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0158 0.0105 0.0105
Loa Loa (eye worm) hypothetical protein 0.0123 0.0079 0.0079
Echinococcus multilocularis peregrin 0.0043 0.002 0.002
Giardia lamblia Flap structure-specific endonuclease 0.0027 0.0009 0.0153
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0002 0.003
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0018 0.0002 0.003
Onchocerca volvulus 0.0489 0.0349 0.6651
Trypanosoma cruzi DNA polymerase kappa, putative 0.0099 0.0061 0.0082
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0018 0.0002 0.0002
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0041 0.0019 0.0017
Schistosoma mansoni regulator of G protein signaling 0.0038 0.0017 0.0017
Brugia malayi Tachykinin-like peptides receptor 99D 0.0019 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.0819 0.0592 0.0592
Schistosoma mansoni transcription factor LCR-F1 0.029 0.0202 0.0202
Loa Loa (eye worm) DR-78 0.0075 0.0044 0.0044
Treponema pallidum NADH oxidase 0.0046 0.0023 0.0482
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0002 0.0015
Echinococcus granulosus kelch ECH associated protein 1 like 0.0093 0.0057 0.0057
Brugia malayi Protein kinase domain containing protein 0.0016 0.0001 0.0001
Loa Loa (eye worm) MBCTL1 0.006 0.0033 0.0033
Echinococcus multilocularis steroid dehydrogenase 0.002 0.0003 0.0003
Toxoplasma gondii NADPH-glutathione reductase 0.0046 0.0023 0.0021
Mycobacterium leprae ROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE 0.002 0.0003 0.0024
Mycobacterium ulcerans UDP-galactopyranose mutase Glf 0.0561 0.0402 1
Leishmania major DNA topoisomerase III, putative 0.0131 0.0086 0.0115
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0089 0.0054 0.0053
Schistosoma mansoni jun-related protein 0.0067 0.0038 0.0038
Loa Loa (eye worm) nuclear factor I 0.0023 0.0005 0.0005
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0158 0.0105 0.0105
Echinococcus granulosus neuropeptides capa receptor 0.0019 0.0003 0.0003
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.0058 0.1355
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0003 0.0002
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0018 0.0002 0.0033
Loa Loa (eye worm) ABC transporter 0.0017 0.0001 0.0001
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0016 0.002
Brugia malayi glutathione reductase 0.0134 0.0087 0.0087
Brugia malayi steroid hormone receptor 0.0158 0.0105 0.0105
Schistosoma mansoni tsg101-related 0.0057 0.0031 0.0031
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0033 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Echinococcus multilocularis caspase 8 0.0089 0.0054 0.0054
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0024 0.0543
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0158 0.0105 0.2008
Schistosoma mansoni smad 0.0018 0.0002 0.0002
Echinococcus granulosus regulator of G protein signaling 7 0.0038 0.0017 0.0017
Echinococcus granulosus tumor protein p63 0.0375 0.0265 0.0265
Mycobacterium tuberculosis Probable monooxygenase 0.0026 0.0008 0.0173
Echinococcus granulosus tm gpcr rhodopsin 0.0019 0.0003 0.0003
Brugia malayi hypothetical protein 0.002 0.0004 0.0004
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.002 0.0003 0.0003
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0018 0.0002 0.0033
Onchocerca volvulus Cathepsin L homolog 0.0018 0.0002 0.0035
Entamoeba histolytica hypothetical protein 0.029 0.0202 0.4708
Echinococcus multilocularis retinol dehydrogenase 11 0.002 0.0003 0.0003
Brugia malayi hypothetical protein 0.0375 0.0265 0.0265
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0022 0.0005 0.0006
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0025 0.0007 0.0157
Echinococcus multilocularis rho GTPase activating protein 20 0.0259 0.018 0.018
Loa Loa (eye worm) hypothetical protein 0.0084 0.005 0.005
Schistosoma mansoni Smad4 0.0018 0.0002 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0002 0.003
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0209 0.0143 0.0143
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.002 0.0003 0.0002
Schistosoma mansoni steroid dehydrogenase 0.002 0.0003 0.0003
Brugia malayi RNA, U transporter 1 0.0084 0.0051 0.0051
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0051 0.0026 0.0026
Trichomonas vaginalis alpha-glucosidase, putative 0.0048 0.0024 0.0548
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0051 0.0026 0.0026
Brugia malayi PXA domain containing protein 0.002 0.0004 0.0004
Trypanosoma cruzi hypothetical protein, conserved 0.0067 0.0038 0.0051
Onchocerca volvulus 0.002 0.0003 0.0063
Echinococcus multilocularis g protein coupled receptor 0.0019 0.0003 0.0003
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0355 0.025 0.4778
Onchocerca volvulus 0.0026 0.0008 0.0152
Trichomonas vaginalis short-chain dehydrogenase, putative 0.002 0.0003 0.0064
Schistosoma mansoni amine GPCR 0.0019 0.0003 0.0003
Brugia malayi jmjC domain containing protein 0.0213 0.0146 0.0146
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0003 0.0024
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0235 0.0162 0.0162
Trichomonas vaginalis conserved hypothetical protein 0.0089 0.0054 0.1259
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0063 0.0035 0.0035
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0049 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.002 0.0003 0.0003
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0003 0.0024
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0003 0.0003
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0003 0.0024
Trypanosoma cruzi DNA topoisomerase IB, large subunit, putative 1.0106 0.743 1
Trypanosoma cruzi metacaspase 5, putative 0.0089 0.0054 0.0072
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0019 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.0018 0.0002 0.0002
Brugia malayi neuropeptide F receptor 0.0019 0.0003 0.0003
Onchocerca volvulus 0.0727 0.0524 1
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0026 0.0008 0.0008
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0038 0.0051
Schistosoma mansoni patched 1 0.0042 0.002 0.002
Trypanosoma cruzi DNA topoisomerase III, putative 0.0259 0.018 0.0241
Schistosoma mansoni nuclear hormone receptor 0.0075 0.0044 0.0044
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0057 0.0031 0.1399
Leishmania major DNA topoisomerase III, putative 0.0302 0.0211 0.0284
Loa Loa (eye worm) MH1 domain-containing protein 0.0041 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0267 0.0186 0.0186
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0213 0.0145 0.0145
Schistosoma mansoni cellular tumor antigen P53 0.0055 0.0029 0.0029
Schistosoma mansoni ATP-binding cassette sub-family g2 (white protein) (abcg2) 0.002 0.0003 0.0003
Echinococcus multilocularis ATP binding cassette sub family G 0.002 0.0003 0.0003
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0047 0.0024 0.0031
Mycobacterium tuberculosis DNA topoisomerase I TopA (omega-protein) (relaxing enzyme) (untwisting enzyme) (swivelase) (type I DNA topoisomerase) (nicking-c 0.0121 0.0078 0.1918
Loa Loa (eye worm) hypothetical protein 0.0026 0.0008 0.0008
Mycobacterium ulcerans carveol-like dehydrogenase 0.002 0.0003 0.0024
Brugia malayi DIX domain containing protein 0.0017 0.0002 0.0002
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0018 0.0002 0.0033
Echinococcus granulosus caspase 8 0.0089 0.0054 0.0054
Loa Loa (eye worm) hypothetical protein 0.002 0.0004 0.0004
Mycobacterium ulcerans ketoacyl reductase 0.002 0.0003 0.0024
Trichomonas vaginalis short-chain dehydrogenase, putative 0.002 0.0003 0.0064
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0002 0.003
Echinococcus granulosus lamin dm0 0.0055 0.0029 0.0029
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.019 0.0129 0.0129
Trypanosoma brucei DNA topoisomerase ii 0.0057 0.0031 0.0041
Brugia malayi Hypothetical 22.2 kDa protein C28F5.2 in chromosome II, putative 0.0026 0.0008 0.0008
Trypanosoma brucei DNA polymerase kappa, putative 0.0078 0.0047 0.0062
Brugia malayi nuclear receptor RXR 0.0075 0.0044 0.0044
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0003 0.0024
Brugia malayi Thioredoxin reductase 0.0134 0.0087 0.0087
Leishmania major oxidoreductase-like protein 0.002 0.0003 0.0004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0008 0.0167
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0089 0.0054 0.1259
Schistosoma mansoni biogenic amine (5HT) receptor 0.0019 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Echinococcus granulosus FTZ F1 alpha 0.0158 0.0105 0.0105
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0046 0.0023 0.003
Brugia malayi Cathepsin L-like precursor 0.0018 0.0002 0.0002
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0017 0.0001 0.0011
Schistosoma mansoni hypothetical protein 0.004 0.0018 0.0018
Echinococcus multilocularis cysteine protease 0.0018 0.0002 0.0002
Loa Loa (eye worm) pax transcription factor protein 2 0.0727 0.0524 0.0524
Schistosoma mansoni hypothetical protein 0.004 0.0018 0.0018
Trypanosoma cruzi hypothetical protein, conserved 0.0067 0.0038 0.0051
Echinococcus multilocularis pyruvate kinase 0.0211 0.0144 0.0144
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0046 0.0023 0.0021
Onchocerca volvulus Cathepsin L homolog 0.0018 0.0002 0.0035
Trypanosoma cruzi metacaspase, putative 0.0089 0.0054 0.0072
Trichomonas vaginalis hydroxyacyl dehydrogenase, putative 0.002 0.0003 0.0064
Loa Loa (eye worm) MH2 domain-containing protein 0.0041 0.0019 0.0019
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0019 0.0003 0.0003
Brugia malayi nuclear receptor NHR-88 0.0158 0.0105 0.0105
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0047 0.0024 0.0514
Schistosoma mansoni amine GPCR 0.0019 0.0003 0.0003
Entamoeba histolytica hypothetical protein 0.002 0.0004 0.0044
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0073 0.0043 0.0041
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.003 0.0011 0.0011
Trypanosoma brucei ABC transporter, putative 0.002 0.0003 0.0004
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0022 0.0005 0.0003
Echinococcus multilocularis axis inhibition protein axin 0.002 0.0004 0.0004
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0005 0.0005
Brugia malayi aryl hydrocarbon receptor AHR-1 0.0018 0.0002 0.0002
Onchocerca volvulus Pyruvate kinase homolog 0.0267 0.0186 0.3542
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.002 0.0003 0.0003
Schistosoma mansoni short chain dehydrogenase 0.002 0.0003 0.0003
Plasmodium vivax ABC transporter G family member 2, putative 0.002 0.0003 0.0002
Schistosoma mansoni neuropeptide F-like receptor 0.0019 0.0003 0.0003
Leishmania major hypothetical protein, conserved 0.0041 0.0019 0.0025
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0084 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0158 0.0105 0.0105
Entamoeba histolytica short chain dehydrogenase family protein 0.002 0.0003 0.0034
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0051 0.0026 0.0026
Echinococcus multilocularis lysosomal alpha glucosidase 0.0156 0.0103 0.0103
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0038 0.0038
Plasmodium vivax DNA topoisomerase 3, putative 0.0252 0.0175 0.0173
Schistosoma mansoni tsg101-related 0.0047 0.0023 0.0023
Giardia lamblia Pyruvate kinase 0.0137 0.009 0.2057
Echinococcus multilocularis segment polarity protein dishevelled 0.0017 0.0002 0.0002
Trypanosoma brucei Metacaspase-4 0.0089 0.0054 0.0072
Brugia malayi Isocitrate dehydrogenase 0.0095 0.0059 0.0059
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0089 0.0054 0.1259
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.002 0.0003 0.0024
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.002 0.0003 0.0026
Brugia malayi Pyruvate kinase, muscle isozyme 0.0267 0.0186 0.0186
Echinococcus multilocularis conserved hypothetical protein 0.0727 0.0524 0.0524
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0185 0.0125 0.0125
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0034 0.0014 0.0014
Schistosoma mansoni growth hormone secretagogue receptor 0.0019 0.0003 0.0003
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0075 0.0044 0.0044
Mycobacterium tuberculosis Probable lipase LipD 0.0033 0.0013 0.0309
Trypanosoma brucei DNA topoisomerase IA, putative 0.0252 0.0175 0.0234
Entamoeba histolytica hypothetical protein 0.002 0.0004 0.0044
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0095 0.0059 0.1442
Mycobacterium ulcerans short-chain dehydrogenase 0.002 0.0003 0.0024
Loa Loa (eye worm) hypothetical protein 0.0075 0.0044 0.0044
Trypanosoma cruzi oxidoreductase-like protein, putative 0.002 0.0003 0.0004
Trypanosoma brucei beta-ketoacyl-ACP reductase 3, putative 0.002 0.0003 0.0004
Schistosoma mansoni inositol monophosphatase 0.0114 0.0073 0.0073
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0004 0.0075
Trypanosoma cruzi cysteine peptidase, putative 0.0067 0.0038 0.0051
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0004 0.0075
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0002 0.0001
Echinococcus granulosus thyroid hormone receptor alpha 0.0075 0.0044 0.0044
Plasmodium falciparum glutathione reductase 0.0046 0.0023 0.0021
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0041 0.0019 0.0017
Loa Loa (eye worm) ctsf protein 0.0018 0.0002 0.0002
Schistosoma mansoni importin beta-1 0.003 0.0011 0.0011
Trichomonas vaginalis glutathione reductase, putative 0.0046 0.0023 0.0526
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0016 0.0354
Echinococcus multilocularis caspase 3 0.0146 0.0096 0.0096
Leishmania major protein kinase, putative 0.0092 0.0057 0.0076
Schistosoma mansoni caspase-7 (C14 family) 0.0235 0.0162 0.0162
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.002 0.0003 0.0026
Brugia malayi hypothetical protein 0.0019 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0046 0.0023 0.003
Onchocerca volvulus 0.0033 0.0013 0.0255
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0075 0.0044 0.0835
Toxoplasma gondii target of rapamycin (TOR), putative 0.0035 0.0015 0.0013
Schistosoma mansoni opsin-like receptor 0.0019 0.0003 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0019 0.0424
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0002 0.003
Echinococcus multilocularis dnaJ subfamily B 0.0819 0.0592 0.0592
Loa Loa (eye worm) jmjC domain-containing protein 0.0158 0.0105 0.0105
Echinococcus granulosus mothers against decapentaplegic 5 0.0041 0.0019 0.0019
Echinococcus multilocularis retinol dehydrogenase 13 0.002 0.0003 0.0003
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0003 0.0002
Brugia malayi Globin family protein 0.0026 0.0008 0.0008
Entamoeba histolytica oxidoreductase, short chain dehydrogenase/reductase family 0.002 0.0003 0.0034
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0019 0.0003 0.0003
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0027 0.0009 0.0007
Onchocerca volvulus Cell death protein 3 homolog 0.0172 0.0115 0.2197
Schistosoma mansoni z-protein (S1r protein) 0.0038 0.0017 0.0017
Trypanosoma brucei hypothetical protein, conserved 0.0033 0.0013 0.0017
Echinococcus granulosus allatostatin A receptor 0.0019 0.0003 0.0003
Echinococcus granulosus JmjC domain containing protein 4 0.0041 0.0019 0.0019
Echinococcus multilocularis fmrfamide receptor 0.0019 0.0003 0.0003
Loa Loa (eye worm) MH1 domain-containing protein 0.0018 0.0002 0.0002
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0003 0.0003
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.002 0.0003 0.0004
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.001 0.0008
Schistosoma mansoni nuclear hormone receptor 0.0158 0.0105 0.0105
Echinococcus granulosus ferritin 0.0034 0.0014 0.0014
Trypanosoma cruzi pyruvate kinase 2, putative 0.0267 0.0186 0.0249
Echinococcus multilocularis orexin receptor type 2 0.0019 0.0003 0.0003
Schistosoma mansoni single-minded 0.0299 0.0209 0.0209
Mycobacterium leprae conserved hypothetical protein 0.0033 0.0013 0.0277
Chlamydia trachomatis DNA gyrase subunit B 0.0057 0.0031 0.0438
Echinococcus multilocularis multidrug and toxin extrusion protein 2 0.0067 0.0038 0.0038
Echinococcus multilocularis carbonyl reductase 1 0.002 0.0003 0.0003
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0156 0.0103 0.0103
Trypanosoma cruzi cytochrome P450, putative 0.0045 0.0022 0.0029
Echinococcus granulosus biogenic amine 5HT receptor 0.0019 0.0003 0.0003
Brugia malayi Smad1 0.0041 0.0019 0.0019
Schistosoma mansoni kinase 0.0097 0.006 0.006
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0002 0.0002
Trypanosoma cruzi metacaspase, putative 0.0089 0.0054 0.0072
Trypanosoma cruzi short-chain dehydrogenase, putative 0.002 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Trichomonas vaginalis alpha-glucosidase, putative 0.0018 0.0002 0.0032
Trypanosoma brucei DNA polymerase IV, putative 0.0099 0.0061 0.0082
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0018 0.0002 0.0033
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0019 0.0003 0.0003
Echinococcus granulosus tm gpcr rhodopsin 0.0019 0.0003 0.0003
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0209 0.0143 0.0143
Leishmania major cathepsin L-like protease 0.0067 0.0038 0.0051
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0018 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0026 0.0008 0.0008
Echinococcus multilocularis smad 0.0041 0.0019 0.0019
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0046 0.0023 0.0021
Plasmodium vivax flap endonuclease 1, putative 0.0027 0.0009 0.0007
Echinococcus multilocularis ubiquitin specific protease 41 0.0036 0.0016 0.0016
Onchocerca volvulus 0.0063 0.0035 0.0667
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0114 0.0073 0.0097
Entamoeba histolytica ABC transporter, putative 0.002 0.0003 0.0036
Trichomonas vaginalis D-aminoacylase, putative 0.0033 0.0013 0.0301
Echinococcus granulosus ATP binding cassette sub family G 0.002 0.0003 0.0003
Leishmania major short chain dehydrogenase, putative 0.002 0.0003 0.0004
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0158 0.0105 0.0105
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.002 0.0003 0.0004
Echinococcus multilocularis cathepsin L cysteine protease 0.0018 0.0002 0.0002
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.002 0.0003 0.0004
Brugia malayi Cytochrome P450 family protein 0.0045 0.0022 0.0022
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0005 0.0005
Echinococcus multilocularis ATP binding cassette sub family G 0.002 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0042 0.002 0.002
Leishmania major importin beta-1 subunit, putative 0.0024 0.0006 0.0008
Trichomonas vaginalis prokaryotic DNA topoisomerase, putative 0.0252 0.0175 0.4081
Echinococcus multilocularis protein patched 0.0042 0.002 0.002
Echinococcus multilocularis cysteine protease 0.0018 0.0002 0.0002
Schistosoma mansoni short chain dehydrogenase 0.002 0.0003 0.0003
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0018 0.0002 0.0002
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0003 0.0004
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0019 0.0003 0.0003
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0084 0.005 0.1495
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0089 0.0054 0.1259
Schistosoma mansoni hypothetical protein 0.004 0.0018 0.0018
Brugia malayi PAS domain containing protein 0.0299 0.0209 0.0209
Schistosoma mansoni DNA polymerase IV / kappa 0.0022 0.0005 0.0005
Giardia lamblia DNA topoisomerase III 0.0131 0.0086 0.1958
Echinococcus granulosus TGF beta signal transducer SmadC 0.0041 0.0019 0.0019
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.002 0.0445
Trypanosoma brucei Vps23 core domain containing protein, putative 0.0022 0.0005 0.0006
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0102 0.0064 0.0064
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0029 0.0011 0.0011
Schistosoma mansoni regulator of G protein signaling 0.002 0.0004 0.0004
Mycobacterium ulcerans dehydrogenase/reductase 0.002 0.0003 0.0024
Trichomonas vaginalis short-chain dehydrogenase, putative 0.002 0.0003 0.0064
Brugia malayi nuclear receptor RXR 0.0084 0.005 0.005
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0038 0.0038
Schistosoma mansoni axis inhibition protein axin 0.002 0.0004 0.0004
Trypanosoma brucei DNA damage repair protein, putative 0.0022 0.0005 0.0006
Trichomonas vaginalis CAMK family protein kinase 0.019 0.0129 0.3007
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0015 0.0000094867 0.0000094867
Loa Loa (eye worm) phosphatidylinositol 3 0.0047 0.0024 0.0024
Echinococcus granulosus thioredoxin glutathione reductase 0.0134 0.0088 0.0088
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0213 0.0146 0.0146
Mycobacterium ulcerans DNA polymerase IV 0.0099 0.0061 0.1479
Mycobacterium ulcerans DNA topoisomerase I 0.0252 0.0175 0.4316
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0018 0.0002 0.0002
Trypanosoma cruzi cytochrome P450, putative 0.0045 0.0022 0.0029
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0036 0.0016 0.002
Schistosoma mansoni multidrug resistance protein 0.0067 0.0038 0.0038
Schistosoma mansoni intermediate filament proteins 0.0055 0.0029 0.0029
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0102 0.0064 0.1541
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0046 0.0023 0.0548
Loa Loa (eye worm) hypothetical protein 0.0026 0.0008 0.0008
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0016 0.0016
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0003 0.0024
Trypanosoma cruzi polo-like protein kinase, putative 0.019 0.0129 0.0173
Trypanosoma brucei glycosyl hydrolase-like protein 0.0018 0.0002 0.0002
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.002 0.0003 0.0063
Trypanosoma cruzi hypothetical protein, conserved 0.0022 0.0005 0.0006
Loa Loa (eye worm) TOPoisomerase family member 0.0057 0.0031 0.0031
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0057 0.0031 0.0749
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0085 0.0051 0.0068
Echinococcus granulosus Protein patched homolog 1 0.0042 0.002 0.002
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0041 0.0019 0.0019
Loa Loa (eye worm) isocitrate dehydrogenase 0.0095 0.0059 0.0059
Loa Loa (eye worm) dehydrogenase 0.002 0.0003 0.0003
Trypanosoma cruzi target of rapamycin kinase 3 0.0038 0.0017 0.0022
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0002 0.003
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0021 0.0005 0.0005
Leishmania major pyruvate kinase 0.0267 0.0186 0.0249
Echinococcus multilocularis oxidoreductase 0.002 0.0003 0.0003
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0002 0.0003
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0046 0.0023 0.003
Loa Loa (eye worm) G-protein coupled receptor 0.0019 0.0003 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0008 0.0167
Onchocerca volvulus 0.0055 0.0029 0.0559
Schistosoma mansoni smad1 5 8 and 0.0041 0.0019 0.0019
Trypanosoma brucei metacaspase 5, putative 0.0089 0.0054 0.0072
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0005
Chlamydia trachomatis pyruvate kinase 0.0267 0.0186 0.8882
Onchocerca volvulus 0.0102 0.0064 0.1215
Plasmodium vivax steroid dehydrogenase, putative 0.002 0.0003 0.0001
Schistosoma mansoni hypothetical protein 0.0158 0.0105 0.0105
Loa Loa (eye worm) DNA topoisomerase III beta-1 0.0131 0.0086 0.0086
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0158 0.0105 0.0105
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0025 0.0007 0.0009
Echinococcus granulosus g protein coupled receptor 0.0019 0.0003 0.0003
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0046 0.0023 0.003
Echinococcus granulosus expressed protein 0.0393 0.0279 0.0279
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0019 0.0003 0.0003
Trypanosoma brucei unspecified product 0.005 0.0025 0.0033
Brugia malayi mbt repeat family protein 0.0053 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0033 0.0013 0.0013
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0042 0.002 0.002
Chlamydia trachomatis DNA gyrase subunit B 0.0057 0.0031 0.0438
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0089 0.0054 0.1259
Trypanosoma brucei metacaspase 0.0089 0.0054 0.0072
Loa Loa (eye worm) dehydrogenase 0.002 0.0003 0.0003
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0041 0.0019 0.0025
Loa Loa (eye worm) hypothetical protein 0.0084 0.005 0.005
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.002 0.0003 0.0024
Plasmodium falciparum phd finger protein, putative 0.0028 0.001 0.0008
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0158 0.0105 0.0105
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0002 0.0046
Brugia malayi nuclear receptor NHR-67 0.0075 0.0044 0.0044
Echinococcus granulosus apoptotic protease activating factor 1 0.0083 0.005 0.005
Leishmania major hypothetical protein, conserved 0.002 0.0003 0.0004
Loa Loa (eye worm) Smad1 0.0041 0.0019 0.0019
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0158 0.0105 0.0105
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0209 0.0143 0.0143
Toxoplasma gondii pyruvate kinase PyKII 0.0137 0.009 0.0088
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.012 0.2808
Brugia malayi hypothetical protein 0.0068 0.0039 0.0039
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0005 0.0005
Mycobacterium leprae Possible regulatory protein 0.0084 0.005 0.1203
Brugia malayi follicle stimulating hormone receptor 0.0019 0.0003 0.0003
Echinococcus multilocularis dna polymerase kappa 0.0099 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.006 0.0033 0.0033
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0038 0.0017 0.0017
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.002 0.0003 0.0003
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0006 0.0139
Toxoplasma gondii HEAT repeat-containing protein 0.003 0.0011 0.0009
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0019 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0019 0.0003 0.0003
Leishmania major quinonoid dihydropteridine reductase 0.002 0.0003 0.0004
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0035 0.0035
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0002 0.003
Trypanosoma cruzi hypothetical protein, conserved 0.0022 0.0005 0.0006
Leishmania major mitochondrial DNA topoisomerase II 0.0057 0.0031 0.0041
Echinococcus granulosus hypothetical protein 0.002 0.0003 0.0003
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0019 0.0003 0.0003
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0089 0.0054 0.0053
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0158 0.0105 0.0105
Giardia lamblia Pyruvate kinase 0.0267 0.0186 0.4313
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0075 0.0044 0.0044
Trichomonas vaginalis CAMK family protein kinase 0.019 0.0129 0.3007
Echinococcus granulosus beta-adrenergic receptor kinase 0.0021 0.0005 0.0005
Echinococcus granulosus neuropeptide FF receptor 2 0.0019 0.0003 0.0003
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0005 0.0006
Trypanosoma cruzi DNA topoisomerase III, putative 0.0131 0.0086 0.0115
Trichomonas vaginalis CAMK family protein kinase 0.019 0.0129 0.3007
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0066 0.0038 0.0038
Schistosoma mansoni hypothetical protein 0.0026 0.0008 0.0008
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0002 0.0003
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0018 0.0002 0.0036
Loa Loa (eye worm) hypothetical protein 0.0026 0.0008 0.0008
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0027 0.0008 0.0008
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0084 0.005 0.0067
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0016 0.002
Schistosoma mansoni opsin-like receptor 0.0019 0.0003 0.0003
Trypanosoma brucei cytochrome P450, putative 0.0045 0.0022 0.0029
Echinococcus granulosus steroid dehydrogenase 0.002 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Echinococcus multilocularis ATP binding cassette sub family G 0.002 0.0003 0.0003
Trichomonas vaginalis glucosylceramidase, putative 0.0272 0.0189 0.4424
Trypanosoma brucei DNA polymerase eta, putative 0.0123 0.0079 0.0106
Schistosoma mansoni myosin xvIII 0.0019 0.0003 0.0003
Schistosoma mansoni short chain dehydrogenase 0.002 0.0003 0.0003
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0034 0.0014 0.0329
Schistosoma mansoni protein phosphatase 2C 0.0041 0.0019 0.0019
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0047 0.0024 0.0031
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0018 0.0002 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0008 0.0167
Leishmania major cathepsin L-like protease 0.0018 0.0002 0.0002
Schistosoma mansoni lamin 0.0055 0.0029 0.0029
Plasmodium falciparum histone acetyltransferase GCN5 0.0159 0.0106 0.0104
Leishmania major quinonoid dihydropteridine reductase 0.002 0.0003 0.0004
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.002 0.0003 0.0003
Echinococcus multilocularis lamin dm0 0.0055 0.0029 0.0029
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0019 0.0003 0.0003
Schistosoma mansoni short chain dehydrogenase 0.002 0.0003 0.0003
Trypanosoma cruzi hypothetical protein, conserved 0.0033 0.0013 0.0017
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Echinococcus granulosus lysine specific demethylase 5A 0.0158 0.0105 0.0105
Loa Loa (eye worm) pyruvate kinase 0.0267 0.0186 0.0186
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0019 0.0003 0.0003
Onchocerca volvulus 0.0018 0.0002 0.0035
Leishmania major quinonoid dihydropteridine reductase 0.002 0.0003 0.0004
Mycobacterium tuberculosis Possible ketoacyl reductase 0.002 0.0003 0.0057
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0429 0.0305 0.0305
Echinococcus multilocularis G-protein coupled receptor, putative 0.0019 0.0003 0.0003
Echinococcus granulosus geminin 0.1201 0.0873 0.0873
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0075 0.0044 0.0044
Trichomonas vaginalis short-chain dehydrogenase, putative 0.002 0.0003 0.0064
Trypanosoma brucei DNA polymerase kappa, putative 0.0049 0.0025 0.0033
Schistosoma mansoni hypothetical protein 0.004 0.0018 0.0018
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0018 0.0002 0.0033
Trichomonas vaginalis estradiol 17 beta-dehydrogenase, putative 0.002 0.0003 0.0064
Echinococcus multilocularis muscleblind protein 0.061 0.0438 0.0438
Brugia malayi neuropeptide F receptor 0.0019 0.0003 0.0003
Echinococcus granulosus neuropeptide Y receptor 0.0019 0.0003 0.0003
Trypanosoma cruzi DNA polymerase kappa, putative 0.0099 0.0061 0.0082
Loa Loa (eye worm) hypothetical protein 0.002 0.0003 0.0003
Plasmodium vivax hypothetical protein, conserved 0.0033 0.0013 0.0012
Trypanosoma brucei 3-keto-dihydrosphingosine reductase 0.002 0.0003 0.0004
Schistosoma mansoni ran 0.0022 0.0005 0.0005
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.002 0.0004 0.0004
Brugia malayi MH2 domain containing protein 0.0018 0.0002 0.0002
Trichomonas vaginalis DNA topoisomerase II, putative 0.0057 0.0031 0.0714
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0046 0.0023 0.1005
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0018 0.0002 0.0002
Toxoplasma gondii melibiase subfamily protein 0.0209 0.0143 0.0141
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Echinococcus granulosus mixed lineage leukemia protein mll 0.0017 0.0001 0.0001
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0003 0.0003
Brugia malayi A-kinase anchor protein 10, precursor 0.002 0.0004 0.0004
Loa Loa (eye worm) oxidoreductase 0.002 0.0003 0.0003
Leishmania major short chain dehydrogenase, putative 0.002 0.0003 0.0004
Leishmania major ATP-binding cassette protein subfamily G, member 4, putative 0.002 0.0003 0.0004
Brugia malayi conserved hypotetical protein 0.0075 0.0044 0.0044
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0158 0.0105 0.0105
Brugia malayi RNA recognition motif domain containing protein 0.0067 0.0038 0.0038
Trypanosoma cruzi polo-like protein kinase, putative 0.019 0.0129 0.0173
Trypanosoma brucei DNA topoisomerase III, putative 0.0131 0.0086 0.0115
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0095 0.0059 0.0078
Echinococcus granulosus carbonyl reductase 1 0.002 0.0003 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0017 0.0376
Echinococcus multilocularis conserved hypothetical protein 0.002 0.0003 0.0003
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0051 0.0026 0.0026
Brugia malayi acetyltransferase, GNAT family protein 0.0589 0.0423 0.0423
Onchocerca volvulus 0.0053 0.0028 0.0531
Brugia malayi PHD-finger family protein 0.0028 0.001 0.001
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0084 0.005 0.005
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.0018 0.0002 0.0002
Plasmodium vivax glutathione reductase, putative 0.0134 0.0087 0.0086
Schistosoma mansoni steroid dehydrogenase 0.002 0.0003 0.0003
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.006 0.0033 0.0033
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0003 0.0004
Echinococcus granulosus axis inhibition protein axin 0.002 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0075 0.0044 0.0044
Echinococcus multilocularis snurportin 1 0.0315 0.0221 0.0221
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0047 0.0024 0.0031
Mycobacterium tuberculosis Probable oxidoreductase 0.002 0.0003 0.0057
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0003 0.0024
Trypanosoma brucei unspecified product 0.0092 0.0057 0.0075
Plasmodium falciparum glutathione reductase 0.0134 0.0087 0.0086
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0046 0.0023 0.0517
Trypanosoma brucei trypanothione reductase 0.0134 0.0087 0.0117
Loa Loa (eye worm) hypothetical protein 0.0084 0.005 0.005
Echinococcus granulosus snurportin 1 0.0315 0.0221 0.0221
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0003 0.0003
Onchocerca volvulus 0.0065 0.0037 0.0699
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0099 0.0061 0.0061
Schistosoma mansoni coup transcription factor 0.0158 0.0105 0.0105
Loa Loa (eye worm) hypothetical protein 0.002 0.0004 0.0004
Plasmodium falciparum DNA repair protein REV1, putative 0.0022 0.0005 0.0003
Echinococcus granulosus ATP binding cassette sub family G 0.002 0.0003 0.0003
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0047 0.0024 0.0514
Echinococcus multilocularis tumor protein p63 0.0375 0.0265 0.0265
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0057 0.0031 0.0029
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0019 0.0003 0.0003
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0066 0.0038 0.0841
Brugia malayi jmjC domain containing protein 0.0041 0.0019 0.0019
Echinococcus granulosus nuclear factor of activated T cells 5 0.0078 0.0046 0.0046
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0019 0.0003 0.0003
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0072 0.0042 0.0042
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0114 0.0073 0.0097
Leishmania major cathepsin L-like protease 0.0067 0.0038 0.0051
Echinococcus granulosus Niemann Pick C1 protein 0.0097 0.006 0.006
Echinococcus multilocularis zinc finger protein 0.0018 0.0002 0.0002
Echinococcus multilocularis microtubule associated protein 2 0.1406 0.1024 0.1024
Loa Loa (eye worm) hypothetical protein 0.0075 0.0044 0.0044
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0002 0.0002
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0066 0.0038 0.005
Brugia malayi beta-lactamase family protein 0.0033 0.0013 0.0013
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.001 0.0214
Loa Loa (eye worm) hypothetical protein 0.003 0.0011 0.0011
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0162 0.0108 0.0108
Brugia malayi Dehydrogenases, short chain protein 2 0.002 0.0003 0.0003
Schistosoma mansoni survival motor neuron protein 0.0291 0.0203 0.0203
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0158 0.0105 0.0105
Schistosoma mansoni biogenic amine receptor 0.0019 0.0003 0.0003
Trypanosoma brucei DNA polymerase IV, putative 0.0099 0.0061 0.0082
Schistosoma mansoni hypothetical protein 0.0028 0.001 0.001
Brugia malayi G protein-coupled receptor 0.0019 0.0003 0.0003
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0078 0.0047 0.1139
Toxoplasma gondii oxidoreductase, putative 0.002 0.0003 0.0002
Loa Loa (eye worm) jmjC domain-containing protein 0.0059 0.0032 0.0032
Echinococcus granulosus serotonin receptor 0.0019 0.0003 0.0003
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0018 0.0002 0.0002
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0003 0.0004
Mycobacterium tuberculosis Probable short-chain dehydrogenase/reductase 0.002 0.0003 0.0057
Schistosoma mansoni steroid dehydrogenase 0.002 0.0003 0.0003
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0033 0.0013 0.0309
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0027 0.0008 0.0008
Brugia malayi polk-prov protein 0.0049 0.0025 0.0025
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0016 0.0001 0.0001
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0182 0.0123 0.0123
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0002 0.003
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0291 0.0203 0.5025
Trypanosoma cruzi cysteine peptidase, putative 0.0067 0.0038 0.0051
Echinococcus granulosus 7tm_1 domain containing protein 0.0019 0.0003 0.0003
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0003 0.0003
Schistosoma mansoni zinc finger protein 0.0018 0.0002 0.0002
Echinococcus granulosus expressed protein 0.0034 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Trichomonas vaginalis alpha-glucosidase, putative 0.0018 0.0002 0.0032
Brugia malayi MH1 domain containing protein 0.0023 0.0005 0.0005
Echinococcus granulosus microtubule associated protein 2 0.1406 0.1024 0.1024
Loa Loa (eye worm) hypothetical protein 0.0036 0.0016 0.0016
Trichomonas vaginalis short-chain dehydrogenase, putative 0.002 0.0003 0.0064
Plasmodium vivax importin-beta 2, putative 0.003 0.0011 0.0009
Loa Loa (eye worm) cytochrome P450 family protein 0.0038 0.0017 0.0017
Brugia malayi hypothetical protein 0.002 0.0003 0.0003
Brugia malayi hypothetical protein 0.0018 0.0002 0.0002
Onchocerca volvulus 0.0019 0.0003 0.0053
Trichomonas vaginalis alpha-glucosidase, putative 0.0018 0.0002 0.0032
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0003 0.0003
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0057 0.0031 0.0591
Trypanosoma cruzi cysteine peptidase, putative 0.0067 0.0038 0.0051
Echinococcus multilocularis pyruvate kinase 0.0137 0.009 0.009
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0055 0.0029 0.0029
Plasmodium falciparum DNA gyrase subunit B 0.0057 0.0031 0.0029
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0033 0.0013 0.0013
Loa Loa (eye worm) nuclear receptor NHR-67 0.0075 0.0044 0.0044
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0084 0.005 0.005
Giardia lamblia DNA damage repair protein 0.0022 0.0005 0.0065
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0589 0.0423 0.0423
Echinococcus multilocularis muscleblind protein 1 0.061 0.0438 0.0438
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0057 0.0031 0.0031
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0033 0.0013 0.0309
Mycobacterium tuberculosis Possible oxidoreductase 0.002 0.0003 0.0057
Schistosoma mansoni DNA topoisomerase II 0.0057 0.0031 0.0031
Brugia malayi hypothetical protein 0.1429 0.1041 0.1041
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0002 0.003
Plasmodium falciparum flap endonuclease 1 0.0027 0.0009 0.0007
Schistosoma mansoni dep domain containing protein 0.0017 0.0002 0.0002
Echinococcus granulosus expressed conserved protein 0.0091 0.0056 0.0056
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0134 0.0087 0.2155
Schistosoma mansoni histamine h1 receptor 0.0019 0.0003 0.0003
Echinococcus multilocularis jumonji domain containing 1A 0.0041 0.0019 0.0019
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.002 0.0003 0.0057
Entamoeba histolytica hypothetical protein 0.002 0.0003 0.0034
Echinococcus granulosus jumonji domain containing 1A 0.0041 0.0019 0.0019
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0213 0.0146 0.0146
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0339 0.0239 0.593
Schistosoma mansoni neuropeptide receptor 0.0019 0.0003 0.0003
Echinococcus multilocularis regulator of G protein signaling 3 0.002 0.0004 0.0004
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0003 0.0003
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0026 0.0008 0.0008
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0095 0.0059 0.0059
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0035 0.0035
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0041 0.0019 0.0019
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0046 0.0023 0.0517
Echinococcus multilocularis lysine specific demethylase 6a 0.0041 0.0019 0.0019
Schistosoma mansoni biogenic amine receptor 0.0019 0.0003 0.0003
Brugia malayi Nuclear hormone receptor E75 0.0075 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Mycobacterium tuberculosis Conserved protein 0.0033 0.0013 0.0309
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0291 0.0203 0.0203
Loa Loa (eye worm) hypothetical protein 0.0075 0.0044 0.0044
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0019 0.0003 0.0003
Trypanosoma brucei membrane transporter protein, putative 0.0067 0.0038 0.0051
Leishmania major adenylate cyclase-like protein 0.0026 0.0008 0.001
Schistosoma mansoni apoferritin-2 0.0034 0.0014 0.0014
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0038 0.0051
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0033 0.0013 0.0309
Brugia malayi ORL1-like opioid receptor 0.0019 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.002 0.0003 0.0003
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0158 0.0105 0.0105
Giardia lamblia Hypothetical protein 0.002 0.0003 0.0018
Echinococcus granulosus histone acetyltransferase KAT2B 0.0573 0.0411 0.0411
Mycobacterium ulcerans bacterioferritin BfrA 0.0034 0.0014 0.0297
Echinococcus multilocularis Niemann Pick C1 protein 0.0139 0.0091 0.0091
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0009 0.0209
Plasmodium falciparum thioredoxin reductase 0.0046 0.0023 0.0021
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0003 0.0003
Echinococcus granulosus citrate lyase subunit beta protein 0.0025 0.0007 0.0007
Brugia malayi putative neuropeptide receptor 0.0019 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Giardia lamblia GTOR 0.0047 0.0024 0.05
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0084 0.005 0.1168
Schistosoma mansoni alpha glucosidase 0.0048 0.0024 0.0024
Trichomonas vaginalis alpha-glucosidase, putative 0.0048 0.0024 0.0548
Onchocerca volvulus 0.0019 0.0003 0.0053
Mycobacterium leprae Probable UDP-galactopyranose mutase Glf (UDP-galp mutase) (NAD+-flavin adenine dinucleotide-requiring enzyme) 0.0561 0.0402 1
Schistosoma mansoni DNA topoisomerase type I 1.0106 0.743 0.743
Leishmania major metacaspase, putative 0.0089 0.0054 0.0072
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0002 0.0003
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0045 0.0022 0.0495
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Giardia lamblia Oxidoreductase, short chain dehydrogenase/reductase family 0.002 0.0003 0.0018
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0158 0.0105 0.0105
Trichomonas vaginalis conserved hypothetical protein 0.0089 0.0054 0.1259
Brugia malayi ABC transporter family protein 0.0017 0.0001 0.0001
Onchocerca volvulus 0.0019 0.0003 0.0053
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0158 0.0105 0.0105
Trypanosoma cruzi hypothetical protein, conserved 0.0067 0.0038 0.0051
Brugia malayi hypothetical protein 0.0019 0.0003 0.0003
Entamoeba histolytica deoxycytidyl transferase, putative 0.0072 0.0042 0.0938
Trypanosoma cruzi DNA damage repair protein, putative 0.0022 0.0005 0.0006
Brugia malayi oxidoreductase 0.002 0.0003 0.0003
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0016 0.0001 0.0001
Echinococcus multilocularis thyroid hormone receptor alpha 0.0158 0.0105 0.0105
Entamoeba histolytica hypothetical protein 0.002 0.0004 0.0044
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.001 0.0214
Echinococcus granulosus hypothetical protein 0.0746 0.0538 0.0538
Brugia malayi hypothetical protein 0.0084 0.005 0.005
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0051 0.0026 0.0026
Toxoplasma gondii DNA topoisomerase family protein 0.0252 0.0175 0.0173
Echinococcus multilocularis SAM and MBT domain containing protein 0.0053 0.0028 0.0028
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0003 0.0003
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0036 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0084 0.005 0.005
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0095 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0026 0.0008 0.0008
Schistosoma mansoni amine GPCR 0.0019 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.0291 0.0203 0.0203
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0015 0.0334
Brugia malayi Melibiase family protein 0.0139 0.0091 0.0091
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0066 0.0038 0.0038
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0114 0.0073 0.169
Brugia malayi aryl hydrocarbon receptor nuclear translocator protein, putative 0.0018 0.0002 0.0002
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0003 0.0024
Trypanosoma brucei glucosidase, putative 0.0048 0.0024 0.0031
Trichomonas vaginalis penicillin-binding protein, putative 0.0033 0.0013 0.0301
Trypanosoma brucei short-chain dehydrogenase, putative 0.002 0.0003 0.0004
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0595 0.0427 1
Trypanosoma brucei chrX additional, unordered contigs 0.0022 0.0005 0.0006
Brugia malayi G protein-coupled receptor F59B2.13 0.0019 0.0003 0.0003
Leishmania major cytochrome p450-like protein 0.0045 0.0022 0.0029
Trichomonas vaginalis prokaryotic DNA topoisomerase, putative 0.0074 0.0044 0.1007
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0003 0.0003
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0041 0.0019 0.0025

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 7.1 mM Inhibition of human leukocyte elastase ChEMBL. 9341917
IC50 (binding) = 7.1 mM Inhibition of human leukocyte elastase ChEMBL. 9341917
IC50 (binding) > 10 mM Inhibition of porcine pancreatic elastase ChEMBL. 9341917
IC50 (binding) > 10 mM Inhibition of porcine pancreatic elastase ChEMBL. 9341917

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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