Detailed information for compound 201942

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 284.249 | Formula: C10H14N5O5
  • H donors: 2 H acceptors: 3 LogP: -0.14 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC[C@@H]1OC(C[C@@H]1N=[N+]=[NH-])n1cc(OC)c(=O)[nH]c1=O
  • InChi: 1S/C10H13N5O5/c1-19-6-3-15(10(18)12-9(6)17)8-2-5(13-14-11)7(4-16)20-8/h3,5,7-8,16H,2,4H2,1H3,(H,12,17,18)/t5-,7-,8?/m1/s1
  • InChiKey: FAAWHRBQBGUHAV-ULFNDUEJSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni GTP-binding protein alpha subunit 0.002 0.0011 0.0012
Entamoeba histolytica cysteine proteinase, putative 0.0309 0.144 1
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0078 0.0299 0.187
Trichomonas vaginalis glucosylceramidase, putative 0.0389 0.1835 0.4647
Schistosoma mansoni lamin 0.0047 0.0145 0.016
Brugia malayi Kringle domain containing protein 0.0062 0.0215 0.0454
Echinococcus granulosus inositol monophosphatase 0.002 0.0011 0.0012
Loa Loa (eye worm) ctsf protein 0.0309 0.144 0.3183
Echinococcus multilocularis cpg binding protein 0.0084 0.0326 0.0359
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0118 0.0494 0.0544
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0093 0.0373 0.0806
Echinococcus granulosus guanine nucleotide binding protein subunit 0.002 0.0011 0.0012
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.002 0.0011 0.0012
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0032 0.0071 0.0078
Onchocerca volvulus 0.0078 0.0296 0.0726
Brugia malayi hypothetical protein 0.004 0.011 0.0221
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0473 0.2252 0.4991
Echinococcus multilocularis 3'(2'),5' bisphosphate nucleotidase 1 0.002 0.0011 0.0012
Trypanosoma cruzi cysteine protease, putative 0.0172 0.0761 0.1685
Schistosoma mansoni cathepsin F (C01 family) 0.0309 0.144 0.1587
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0032 0.0071 0.0078
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.002 0.0011 0.002
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0044 0.0126 0.0274
Echinococcus multilocularis calpain A 0.0121 0.0509 0.0561
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0078 0.0299 0.075
Loa Loa (eye worm) hypothetical protein 0.0062 0.0215 0.0456
Onchocerca volvulus 0.0054 0.0179 0.0428
Brugia malayi Cathepsin L-like precursor 0.0309 0.144 0.3182
Loa Loa (eye worm) hypothetical protein 0.0118 0.0494 0.1077
Entamoeba histolytica cysteine proteinase, putative 0.0172 0.0761 0.5277
Brugia malayi Inositol monophosphatase family protein 0.002 0.0011 0.0000013
Trichomonas vaginalis alpha-glucosidase, putative 0.0154 0.0674 0.1703
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0309 0.144 0.3646
Giardia lamblia Cathepsin B precursor 0.0078 0.0299 0.1812
Giardia lamblia Hypothetical protein 0.0078 0.0299 0.1812
Brugia malayi Cathepsin L-like precursor 0.0309 0.144 0.3182
Onchocerca volvulus 0.0309 0.144 0.3633
Entamoeba histolytica hypothetical protein 0.0078 0.0299 0.2057
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0309 0.144 0.9
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0341 0.1599 1
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0078 0.0299 0.0329
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0927 0.4503 0.4963
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0309 0.144 0.9
Echinococcus granulosus geminin 0.0617 0.2966 0.3268
Schistosoma mansoni lamin 0.0047 0.0145 0.016
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0309 0.144 0.3646
Brugia malayi latrophilin 2 splice variant baaae 0.0025 0.0035 0.0053
Schistosoma mansoni inositol monophosphatase 0.0194 0.087 0.0959
Echinococcus multilocularis inositol monophosphatase 0.002 0.0011 0.0012
Loa Loa (eye worm) hypothetical protein 0.004 0.011 0.0224
Trichomonas vaginalis maltase-glucoamylase, putative 0.0057 0.0195 0.0487
Loa Loa (eye worm) hypothetical protein 0.0078 0.0299 0.0643
Brugia malayi Trypsin-like protease protein 5 0.0054 0.0179 0.0375
Trichomonas vaginalis bromodomain-containing protein, putative 0.0073 0.0272 0.0683
Loa Loa (eye worm) hypothetical protein 0.0078 0.0299 0.0643
Brugia malayi F/Y-rich N-terminus family protein 0.0029 0.0054 0.0097
Brugia malayi Protein kinase domain containing protein 0.0062 0.0215 0.0454
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0054 0.0179 0.0198
Loa Loa (eye worm) hypothetical protein 0.0054 0.0179 0.0378
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0073 0.0272 0.1646
Brugia malayi RNA recognition motif domain containing protein 0.0103 0.042 0.091
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0309 0.144 0.3646
Brugia malayi acetyltransferase, GNAT family protein 0.0244 0.1119 0.2467
Echinococcus multilocularis thioredoxin glutathione reductase 0.0041 0.0114 0.0126
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0309 0.144 0.3646
Entamoeba histolytica cysteine protease, putative 0.0172 0.0761 0.5277
Brugia malayi cathepsin L-like precursor 0.0215 0.0977 0.2152
Trichomonas vaginalis alpha-glucosidase, putative 0.0154 0.0674 0.1703
Entamoeba histolytica cysteine protease, putative 0.0172 0.0761 0.5277
Schistosoma mansoni cathepsin s 0.0093 0.0373 0.0411
Loa Loa (eye worm) hypothetical protein 0.0023 0.0025 0.0033
Plasmodium falciparum thioredoxin reductase 0.0041 0.0114 0.0634
Plasmodium vivax RNA helicase-1, putative 0.0153 0.067 0.4408
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0032 0.0071 0.015
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0078 0.0299 0.187
Plasmodium vivax calpain, putative 0.0044 0.0126 0.0693
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0078 0.0299 0.075
Leishmania major hypothetical protein, conserved 0.004 0.011 0.0672
Schistosoma mansoni cercarial elastase (S01 family) 0.0054 0.0179 0.0198
Onchocerca volvulus 0.0054 0.0179 0.0428
Giardia lamblia Cathepsin L precursor 0.0078 0.0299 0.1812
Brugia malayi Glycosyl hydrolases family 31 protein 0.0695 0.3354 0.7441
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0169 0.0748 0.0824
Entamoeba histolytica cysteine protease, putative 0.0172 0.0761 0.5277
Plasmodium falciparum ataxin-2 like protein, putative 0.004 0.011 0.0605
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0058 0.0198 0.0219
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0078 0.0299 0.075
Schistosoma mansoni calpain-7 (C02 family) 0.0049 0.0152 0.0167
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0044 0.0126 0.0274
Loa Loa (eye worm) hypothetical protein 0.0022 0.0019 0.0021
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0078 0.0299 0.075
Trypanosoma cruzi cysteine peptidase, putative 0.0309 0.144 0.3194
Loa Loa (eye worm) inositol-1 0.0194 0.087 0.1915
Brugia malayi Glycosyl hydrolases family 31 protein 0.0057 0.0195 0.041
Giardia lamblia Cathepsin B precursor 0.0078 0.0299 0.1812
Plasmodium vivax unspecified product 0.0093 0.0373 0.2378
Trypanosoma cruzi cysteine peptidase, putative 0.0309 0.144 0.3194
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0309 0.144 0.3646
Brugia malayi Cathepsin L-like precursor 0.0309 0.144 0.3182
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0309 0.144 0.3646
Schistosoma mansoni importin beta-1 0.0023 0.0025 0.0027
Schistosoma mansoni myo inositol monophosphatase 0.002 0.0011 0.0012
Trypanosoma brucei Eukaryotic initiation factor 4A-1 0.0153 0.067 0.4152
Loa Loa (eye worm) hypothetical protein 0.0078 0.0299 0.0643
Trichomonas vaginalis alpha-glucosidase, putative 0.0154 0.0674 0.1703
Giardia lamblia Cathepsin B precursor 0.0341 0.1599 1
Brugia malayi calpain family protein 1 0.0116 0.0483 0.105
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0309 0.144 0.1587
Giardia lamblia Cathepsin B precursor 0.0341 0.1599 1
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.1173 0.2968
Echinococcus multilocularis enteropeptidase 0.0054 0.0179 0.0198
Schistosoma mansoni hypothetical protein 0.004 0.0107 0.0118
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0054 0.0179 0.0198
Brugia malayi cytoplasmic intermediate filament protein 0.0025 0.0036 0.0056
Plasmodium falciparum glutathione reductase 0.0041 0.0114 0.0634
Toxoplasma gondii cathepsin CPL 0.0309 0.144 0.9
Schistosoma mansoni calpain C (C02 family) 0.0044 0.0126 0.0139
Trichomonas vaginalis myo inositol monophosphatase, putative 0.002 0.0011 0.002
Onchocerca volvulus 0.0319 0.149 0.3758
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0153 0.067 0.1483
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0032 0.0071 0.015
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0194 0.087 0.1927
Entamoeba histolytica cysteine protease, putative 0.0172 0.0761 0.5277
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0057 0.0195 0.0487
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0078 0.0299 0.075
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0341 0.1599 0.1762
Echinococcus multilocularis muscleblind protein 0.027 0.1247 0.1374
Entamoeba histolytica cysteine protease, putative 0.0172 0.0761 0.5277
Trichomonas vaginalis D-aminoacylase, putative 0.0319 0.149 0.3771
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.004 0.0107 0.0214
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0309 0.144 1
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0319 0.149 0.3292
Brugia malayi Papain family cysteine protease containing protein 0.0309 0.144 0.3182
Echinococcus multilocularis lysosomal alpha glucosidase 0.0695 0.3354 0.3696
Echinococcus granulosus cathepsin b 0.0927 0.4503 0.4963
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0032 0.0071 0.0078
Loa Loa (eye worm) RNA binding protein 0.0103 0.042 0.0912
Schistosoma mansoni hypothetical protein 0.0617 0.2966 0.3268
Trypanosoma cruzi PAB1-binding protein , putative 0.004 0.011 0.0238
Mycobacterium tuberculosis Probable esterase LipL 0.0319 0.149 0.148
Loa Loa (eye worm) hypothetical protein 0.0149 0.0649 0.1423
Brugia malayi hypothetical protein 0.0195 0.0874 0.1922
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0073 0.0272 0.0683
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0153 0.067 0.0739
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0078 0.0299 0.075
Brugia malayi cathepsin F-like cysteine proteinase 0.0078 0.0299 0.0641
Trypanosoma brucei importin beta-1 subunit, putative 0.0023 0.0025 0.0087
Giardia lamblia Cathepsin L precursor 0.0078 0.0299 0.1812
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.002 0.0011 0.0012
Plasmodium vivax vivapain-1 0.0172 0.0761 0.503
Onchocerca volvulus 0.0054 0.0179 0.0428
Echinococcus multilocularis muscleblind protein 1 0.027 0.1247 0.1374
Mycobacterium tuberculosis Conserved protein 0.0319 0.149 0.148
Trichomonas vaginalis set domain proteins, putative 0.0815 0.3945 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0057 0.0195 0.0487
Loa Loa (eye worm) histone methyltransferase 0.0028 0.0048 0.0086
Loa Loa (eye worm) calpain family protein 1 0.0085 0.0332 0.0717
Echinococcus granulosus transmembrane protease serine 3 0.0054 0.0179 0.0198
Echinococcus granulosus muscleblind protein 0.027 0.1247 0.1374
Trichomonas vaginalis alpha-glucosidase, putative 0.0154 0.0674 0.1703
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.002 0.0011 0.0012
Brugia malayi beta-lactamase family protein 0.0319 0.149 0.3292
Schistosoma mansoni tar DNA-binding protein 0.0103 0.042 0.0463
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0057 0.0195 0.0426
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0162 0.0714 0.0787
Leishmania major eukaryotic initiation factor 4a, putative 0.0153 0.067 0.4181
Onchocerca volvulus Cathepsin L homolog 0.0309 0.144 0.3633
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0309 0.144 0.9
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0149 0.0649 0.0715
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0194 0.087 0.5812
Onchocerca volvulus 0.0309 0.144 0.3633
Loa Loa (eye worm) trypsin family protein 0.0054 0.0179 0.0378
Loa Loa (eye worm) DEAH box polypeptide 35 0.0406 0.1923 0.4258
Giardia lamblia Cathepsin L precursor 0.0078 0.0299 0.1812
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0078 0.0299 0.075
Trypanosoma brucei glucosidase, putative 0.0154 0.0674 0.4178
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0078 0.0299 0.0329
Loa Loa (eye worm) calpain 0.0044 0.0126 0.0259
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0595 0.2857 0.6336
Onchocerca volvulus Cathepsin F homolog 0.0309 0.144 0.3633
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0023 0.0025 0.0027
Giardia lamblia Cathepsin B precursor 0.0341 0.1599 1
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0094 0.0376 0.0365
Loa Loa (eye worm) beta-lactamase 0.0319 0.149 0.3293
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.002 0.0011 0.002
Brugia malayi fibroinase precursor 0.0078 0.0299 0.0641
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0154 0.0674 0.4671
Loa Loa (eye worm) GTP-binding regulatory protein alpha chain 0.002 0.0011 0.0003
Giardia lamblia Cathepsin B precursor 0.0078 0.0299 0.1812
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0078 0.0299 0.0641
Schistosoma mansoni cercarial elastase (S01 family) 0.0054 0.0179 0.0198
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.002 0.0011 0.0012
Trypanosoma cruzi hypothetical protein, conserved 0.0062 0.0215 0.0471
Loa Loa (eye worm) hypothetical protein 0.0032 0.0071 0.0136
Entamoeba histolytica hypothetical protein 0.006 0.0207 0.1416
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0037 0.0092 0.0181
Schistosoma mansoni cathepsin F (C01 family) 0.0309 0.144 0.1587
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-6 subunit 0.002 0.0011 0.0003
Brugia malayi Trypsin family protein 0.0054 0.0179 0.0375
Loa Loa (eye worm) hypothetical protein 0.0025 0.0035 0.0055
Onchocerca volvulus 0.0309 0.144 0.3633
Echinococcus multilocularis musashi 0.0047 0.0145 0.016
Schistosoma mansoni bromodomain containing protein 0.0061 0.0213 0.0234
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0044 0.0126 0.0726
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0309 0.144 0.3646
Mycobacterium ulcerans aldehyde dehydrogenase 0.0162 0.0714 0.4753
Loa Loa (eye worm) hypothetical protein 0.0153 0.067 0.147
Brugia malayi PHD-finger family protein 0.003 0.0061 0.011
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0319 0.149 0.148
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0194 0.087 0.22
Trichomonas vaginalis glucosylceramidase, putative 0.0389 0.1835 0.4647
Loa Loa (eye worm) hypothetical protein 0.0031 0.0063 0.0117
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0319 0.149 0.1642
Echinococcus granulosus snurportin 1 0.0247 0.1131 0.1247
Brugia malayi Pre-SET motif family protein 0.0104 0.0426 0.0924
Mycobacterium ulcerans hypothetical protein 0.0319 0.149 1
Toxoplasma gondii ABC1 family protein 0.0319 0.149 0.9311
Leishmania major hypothetical protein, conserved 0.0319 0.149 0.9314
Schistosoma mansoni cathepsin S (C01 family) 0.0078 0.0299 0.0329
Plasmodium vivax serine-repeat antigen (SERA) 0.0078 0.0299 0.187
Trichomonas vaginalis esterase, putative 0.0319 0.149 0.3771
Trichomonas vaginalis D-aminoacylase, putative 0.0319 0.149 0.3771
Brugia malayi RNA, U transporter 1 0.0066 0.0236 0.05
Brugia malayi TAR-binding protein 0.0103 0.042 0.091
Entamoeba histolytica cysteine protease, putative 0.0172 0.0761 0.5277
Trypanosoma brucei hypothetical protein, conserved 0.0319 0.149 0.9311
Mycobacterium leprae conserved hypothetical protein 0.0319 0.149 1
Brugia malayi Papain family cysteine protease containing protein 0.0172 0.0761 0.1671
Schistosoma mansoni hypothetical protein 0.002 0.0011 0.0012
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0162 0.0714 0.0787
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0341 0.1599 0.4048
Giardia lamblia Cysteine protease 0.0078 0.0299 0.1812
Toxoplasma gondii cathepsin CPC2 0.0078 0.0299 0.1812
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0927 0.4503 0.4963
Echinococcus granulosus survival motor neuron protein 1 0.0195 0.0874 0.0963
Loa Loa (eye worm) hypothetical protein 0.0319 0.149 0.3293
Loa Loa (eye worm) calpain family protein 1 0.0116 0.0483 0.1053
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0215 0.0977 0.2472
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0153 0.067 0.1483
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0154 0.0674 0.1703
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0121 0.0509 0.0561
Trichomonas vaginalis alpha-glucosidase, putative 0.0057 0.0195 0.0487
Echinococcus multilocularis hypothetical protein 0.0044 0.0126 0.0139
Leishmania major alpha glucosidase II subunit, putative 0.0154 0.0674 0.4206
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0078 0.0299 0.1812
Loa Loa (eye worm) intermediate filament protein 0.0047 0.0145 0.0301
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0121 0.0509 0.0561
Mycobacterium ulcerans lipase LipD 0.0319 0.149 1
Loa Loa (eye worm) hypothetical protein 0.0215 0.0977 0.2154
Onchocerca volvulus Huntingtin homolog 0.011 0.0456 0.1132
Schistosoma mansoni hypothetical protein 0.0025 0.0035 0.0038
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0003
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.1173 0.2968
Mycobacterium leprae Probable lipase LipE 0.0319 0.149 1
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0078 0.0299 0.187
Trichomonas vaginalis glucosylceramidase, putative 0.0269 0.1241 0.3141
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1435 0.7015 0.7732
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0032 0.0071 0.0171
Loa Loa (eye worm) hypothetical protein 0.0045 0.0131 0.0269
Plasmodium falciparum ataxin-2 like protein, putative 0.004 0.011 0.0605
Mycobacterium ulcerans aldehyde dehydrogenase 0.0162 0.0714 0.4753
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0032 0.0071 0.0376
Echinococcus multilocularis cysteine protease 0.0309 0.144 0.1587
Loa Loa (eye worm) hypothetical protein 0.0215 0.0977 0.2154
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0078 0.0299 0.0643
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0032 0.0071 0.0133
Echinococcus multilocularis cathepsin L cysteine protease 0.0309 0.144 0.1587
Plasmodium vivax vivapain-2 0.0309 0.144 0.9663
Schistosoma mansoni hypothetical protein 0.002 0.0011 0.0012
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0094 0.0376 0.0365
Brugia malayi cathepsin L-like cysteine proteinase 0.0078 0.0299 0.0641
Schistosoma mansoni hypothetical protein 0.111 0.5409 0.5961
Brugia malayi eukaryotic initiation factor 4A 0.0153 0.067 0.1468
Entamoeba histolytica 3(2),5-bisphosphate nucleotidase, putative 0.002 0.0011 0.0055
Entamoeba histolytica acetyltransferase, GNAT family 0.0065 0.0234 0.1604
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0104 0.0428 0.2819
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0032 0.0071 0.047
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.002 0.0011 0.0012
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0023 0.0024 0.0026
Onchocerca volvulus 0.0309 0.144 0.3633
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-12 subunit 0.002 0.0011 0.0003
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0044 0.0126 0.0274
Entamoeba histolytica cysteine protease, putative 0.0078 0.0299 0.2057
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0078 0.0299 0.187
Echinococcus multilocularis beta LACTamase domain containing family member 0.0319 0.149 0.1642
Entamoeba histolytica protein kinase, putative 0.003 0.0061 0.0406
Brugia malayi Pre-SET motif family protein 0.0716 0.3457 0.767
Loa Loa (eye worm) hypothetical protein 0.0023 0.0024 0.0031
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0309 0.144 0.3646
Plasmodium vivax glutathione reductase, putative 0.0041 0.0114 0.0612
Entamoeba histolytica cysteine protease, putative 0.0078 0.0299 0.2057
Onchocerca volvulus 0.0062 0.0215 0.0518
Loa Loa (eye worm) cathepsin B 0.0341 0.1599 0.3537
Toxoplasma gondii histone lysine methyltransferase SET1 0.0159 0.0699 0.4334
Echinococcus granulosus enteropeptidase 0.0054 0.0179 0.0198
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.002 0.0011 0.0012
Entamoeba histolytica cysteine proteinase, putative 0.0215 0.0977 0.678
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0473 0.2252 0.499
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0154 0.0674 0.1479
Plasmodium falciparum cysteine proteinase falcipain 3 0.0309 0.144 1
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.006 0.0207 0.0228
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0172 0.0761 0.0839
Onchocerca volvulus 0.0149 0.0649 0.1622
Trichomonas vaginalis alpha-glucosidase, putative 0.0057 0.0195 0.0487
Trypanosoma cruzi hypothetical protein, conserved 0.0154 0.0674 0.1492
Brugia malayi Cathepsin L-like precursor 0.0309 0.144 0.3182
Mycobacterium ulcerans hypothetical protein 0.0054 0.0179 0.114
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0078 0.0299 0.187
Leishmania major cathepsin L-like protease 0.0309 0.144 0.9005
Entamoeba histolytica cysteine protease, putative 0.0172 0.0761 0.5277
Echinococcus multilocularis eukaryotic initiation factor 4A 0.0153 0.067 0.0739
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0319 0.149 0.148
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0309 0.144 0.3646
Toxoplasma gondii HEAT repeat-containing protein 0.0023 0.0025 0.0087
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0047 0.0145 0.0301
Trypanosoma brucei calpain-like protein, putative 0.0044 0.0126 0.0726
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0057 0.0195 0.0468
Schistosoma mansoni GTP-binding protein (I) alpha subunit gnai 0.002 0.0011 0.0012
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0473 0.2252 0.2482
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0319 0.149 0.148
Schistosoma mansoni tar DNA-binding protein 0.0103 0.042 0.0463
Loa Loa (eye worm) hypothetical protein 0.011 0.0456 0.0994
Giardia lamblia Cathepsin B precursor 0.0078 0.0299 0.1812
Onchocerca volvulus 0.0309 0.144 0.3633
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0078 0.0299 0.0329
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0309 0.144 0.9
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0078 0.0299 0.1936
Loa Loa (eye worm) hypothetical protein 0.0057 0.0195 0.0412
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0309 0.144 0.3646
Echinococcus multilocularis dnaJ subfamily B 0.111 0.5409 0.5961
Brugia malayi Inositol monophosphatase family protein 0.002 0.0011 0.0000013
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0044 0.0126 0.0772
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0037 0.0092 0.0183
Leishmania major eukaryotic initiation factor 4a, putative 0.0153 0.067 0.4181
Loa Loa (eye worm) hypothetical protein 0.027 0.1247 0.2753
Loa Loa (eye worm) hypothetical protein 0.0157 0.069 0.1513
Trypanosoma cruzi cysteine peptidase, putative 0.0309 0.144 0.3194
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0044 0.0126 0.0274
Schistosoma mansoni cercarial elastase (S01 family) 0.0054 0.0179 0.0198
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0309 0.144 0.3646
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0023 0.0025 0.0027
Trypanosoma cruzi cysteine peptidase, putative 0.0172 0.0761 0.1685
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0025 0.0036 0.0058
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0071 0.0171
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0172 0.0761 0.1924
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0194 0.087 0.22
Onchocerca volvulus Glucosylceramidase homolog 0.0255 0.1173 0.2954
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0078 0.0299 0.1812
Plasmodium falciparum cysteine proteinase falcipain 1 0.0172 0.0761 0.5205
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0104 0.0426 0.047
Echinococcus multilocularis ubiquitin specific protease 41 0.0032 0.0071 0.0078
Trypanosoma cruzi major cysteine proteinase, putative 0.0078 0.0299 0.0657
Trichomonas vaginalis alpha-glucosidase, putative 0.0154 0.0674 0.1703
Loa Loa (eye worm) hypothetical protein 0.0406 0.1923 0.4258
Echinococcus granulosus guanine nucleotide binding protein G protein 0.002 0.0011 0.0012
Onchocerca volvulus Huntingtin homolog 0.011 0.0456 0.1132
Schistosoma mansoni cercarial elastase (S01 family) 0.0054 0.0179 0.0198
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0078 0.0299 0.075
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0121 0.0509 0.0561
Onchocerca volvulus 0.0215 0.0977 0.2457
Brugia malayi intermediate filament protein 0.0047 0.0145 0.0298
Trichomonas vaginalis alpha-glucosidase, putative 0.0057 0.0195 0.0487
Loa Loa (eye worm) TAR-binding protein 0.0103 0.042 0.0912
Echinococcus granulosus calpain 0.0044 0.0126 0.0139
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0078 0.0299 0.1936
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0032 0.0071 0.0171
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0149 0.0649 0.0715
Plasmodium vivax unspecified product 0.0078 0.0299 0.187
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0032 0.0071 0.0424
Trypanosoma brucei calpain-like protein, putative 0.0044 0.0126 0.0726
Plasmodium vivax unspecified product 0.0172 0.0761 0.503
Echinococcus multilocularis calpain 5 0.0044 0.0126 0.0139
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0078 0.0299 0.075
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.002 0.0011 0.0012
Toxoplasma gondii LsmAD domain-containing protein 0.004 0.011 0.0625
Echinococcus multilocularis cysteine protease 0.0309 0.144 0.1587
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0044 0.0126 0.0274
Echinococcus granulosus histone acetyltransferase KAT2B 0.0235 0.1076 0.1186
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0062 0.0215 0.1298
Schistosoma mansoni cercarial elastase (S01 family) 0.0054 0.0179 0.0198
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0162 0.0714 0.0704
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.006 0.0207 0.0228
Trypanosoma cruzi cruzipain precursor, putative 0.0093 0.0373 0.0822
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0309 0.144 0.3646
Echinococcus granulosus cathepsin L 0.0172 0.0761 0.0839
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0054 0.0179 0.0198
Chlamydia trachomatis 3'(2'),5'-bisphosphate nucleotidase CysQ 0.002 0.0011 0.5
Onchocerca volvulus 0.0309 0.144 0.3633
Entamoeba histolytica cysteine protease, putative 0.0078 0.0299 0.2057
Giardia lamblia Hypothetical protein 0.0078 0.0299 0.1812
Trichomonas vaginalis conserved hypothetical protein 0.0078 0.0299 0.075
Schistosoma mansoni zinc finger protein 0.0026 0.0039 0.0043
Trichomonas vaginalis glucosylceramidase, putative 0.0389 0.1835 0.4647
Mycobacterium tuberculosis Probable reductase 0.0094 0.0376 0.0365
Brugia malayi Bromodomain containing protein 0.007 0.0259 0.0553
Echinococcus granulosus cathepsin l1 0.0309 0.144 0.1587
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0054 0.0179 0.0198
Plasmodium falciparum serine repeat antigen 6 0.0078 0.0299 0.1936
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0054 0.0179 0.0198
Brugia malayi Trypsin family protein 0.0054 0.0179 0.0375
Loa Loa (eye worm) CXXC zinc finger family protein 0.0078 0.0296 0.0638
Schistosoma mansoni trimeric G-protein alpha o subunit 0.002 0.0011 0.0012
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0172 0.0761 0.0839
Entamoeba histolytica cysteine protease, putative 0.0078 0.0299 0.2057
Trypanosoma cruzi kinesin, putative 0.003 0.0061 0.013
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0057 0.0195 0.1335
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0309 0.144 0.3646
Mycobacterium tuberculosis Probable lipase LipD 0.0319 0.149 0.148
Leishmania major myo-inositol-1 phosphatase, putative 0.002 0.0011 0.0049
Onchocerca volvulus 0.0047 0.0145 0.034
Brugia malayi cathepsin F-like cysteine proteinase 0.0093 0.0373 0.0806
Echinococcus granulosus calpain A 0.0044 0.0126 0.0139
Entamoeba histolytica 3(2),5-bisphosphate nucleotidase, putative 0.002 0.0011 0.0055
Trichomonas vaginalis D-aminoacylase, putative 0.0319 0.149 0.3771
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0104 0.0426 0.2615
Echinococcus multilocularis glycoprotein Antigen 5 0.0054 0.0179 0.0198
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0309 0.144 0.3646
Echinococcus granulosus cpg binding protein 0.0084 0.0326 0.0359
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0473 0.2252 0.2482
Echinococcus multilocularis cathepsin L cysteine protease 0.0309 0.144 0.1587
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0309 0.144 0.9
Leishmania major cathepsin L-like protease 0.0309 0.144 0.9005
Plasmodium vivax vivapain-3 0.0172 0.0761 0.503
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0154 0.0674 0.1703
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0927 0.4503 0.4963
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0194 0.087 0.1927
Schistosoma mansoni GTP-binding protein alpha subunit 0.002 0.0011 0.0012
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0309 0.144 0.9
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0003
Brugia malayi beta-lactamase family protein 0.0319 0.149 0.3292
Onchocerca volvulus 0.0319 0.149 0.3758
Echinococcus multilocularis lamin 0.0047 0.0145 0.016
Schistosoma mansoni pap-inositol-14-phosphatase 0.002 0.0011 0.0012
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0078 0.0299 0.187
Entamoeba histolytica cysteine proteinase, putative 0.0309 0.144 1
Echinococcus granulosus 3'2'5' bisphosphate nucleotidase 1 0.002 0.0011 0.0012
Trichomonas vaginalis diphosphonucleoside phosphohydrolase, putative 0.002 0.0011 0.002
Onchocerca volvulus 0.0054 0.0179 0.0428
Loa Loa (eye worm) hypothetical protein 0.0102 0.0418 0.0908
Schistosoma mansoni cpg binding protein 0.0078 0.0296 0.0327
Mycobacterium ulcerans aldehyde dehydrogenase 0.0162 0.0714 0.4753
Trichomonas vaginalis sucrase-isomaltase, putative 0.0154 0.0674 0.1703
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0003
Echinococcus multilocularis inositol monophosphatase 1 0.0194 0.087 0.0959
Loa Loa (eye worm) hypothetical protein 0.0057 0.0191 0.0403
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0078 0.0299 0.0329
Echinococcus multilocularis cathepsin L 0.0078 0.0299 0.0329
Echinococcus multilocularis tissue type plasminogen activator 0.0062 0.0215 0.0237
Onchocerca volvulus 0.0078 0.0299 0.0731
Trichomonas vaginalis GTP-binding protein (z) alpha subunit, gnaz, putative 0.002 0.0011 0.002
Trichomonas vaginalis glucosylceramidase, putative 0.0389 0.1835 0.4647
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0309 0.144 0.3646
Entamoeba histolytica DEAD/DEAH box helicase, putative 0.0153 0.067 0.4643
Giardia lamblia Cysteine protease 0.0078 0.0299 0.1812
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0309 0.144 0.3646
Leishmania major cathepsin L-like protease 0.0309 0.144 0.9005
Onchocerca volvulus 0.0309 0.144 0.3633
Leishmania major cathepsin L-like protease 0.0309 0.144 0.9005
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.002 0.0011 0.0012
Giardia lamblia Cysteine protease 0.0078 0.0299 0.1812
Brugia malayi calpain 5 0.003 0.0061 0.0112
Mycobacterium tuberculosis Conserved protein 0.0319 0.149 0.148
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0927 0.4503 1
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0099 0.0399 0.044
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0473 0.2252 0.2482
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0104 0.0426 0.047
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0104 0.0426 0.047
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0078 0.0299 0.1812
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0309 0.144 0.9
Echinococcus granulosus calpain 5 0.0044 0.0126 0.0139
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0927 0.4503 0.4963
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0078 0.0299 0.0329
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.1173 0.2968
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0032 0.0071 0.0078
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0041 0.0114 0.0104
Onchocerca volvulus Inositol monophosphatase 3 homolog 0.002 0.0011 0.0000014844
Brugia malayi Trypsin family protein 0.0149 0.0649 0.1421
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0078 0.0299 0.075
Echinococcus granulosus cathepsin l cysteine peptidase 0.0309 0.144 0.1587
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0044 0.0126 0.0274
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.002 0.0011 0.0012
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0174 0.077 0.5132
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0174 0.077 0.076
Schistosoma mansoni microtubule-associated protein tau 0.185 0.9074 1
Loa Loa (eye worm) calpain 5 0.003 0.0061 0.0115
Entamoeba histolytica cysteine proteinase 2 0.0172 0.0761 0.5277
Brugia malayi Papain family cysteine protease containing protein 0.0078 0.0299 0.0641
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0309 0.144 0.3646
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0309 0.144 0.3646
Echinococcus granulosus guanine nucleotide binding protein G protein 0.002 0.0011 0.0012
Trypanosoma brucei antigen, putative 0.0044 0.0126 0.0726
Plasmodium falciparum serine repeat antigen 4 0.0078 0.0299 0.1936
Echinococcus granulosus tar DNA binding protein 0.0103 0.042 0.0463
Schistosoma mansoni cathepsin F (C01 family) 0.0215 0.0977 0.1077
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0172 0.0761 0.1685
Echinococcus multilocularis zinc finger protein 0.0026 0.0039 0.0043
Schistosoma mansoni tar DNA-binding protein 0.0103 0.042 0.0463
Loa Loa (eye worm) hypothetical protein 0.0093 0.0373 0.0809
Plasmodium vivax thioredoxin reductase, putative 0.0041 0.0114 0.0612
Brugia malayi cathepsin B-like cysteine proteinase 0.0927 0.4503 1
Leishmania major cathepsin L-like protease 0.0309 0.144 0.9005
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0473 0.2252 0.2482
Schistosoma mansoni hypothetical protein 0.006 0.0207 0.0228
Trichomonas vaginalis glucosylceramidase, putative 0.0269 0.1241 0.3141
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0078 0.0299 0.187
Echinococcus granulosus histone lysine methyltransferase setb 0.0118 0.0494 0.0544
Echinococcus multilocularis cathepsin L 0.0172 0.0761 0.0839
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0215 0.0977 0.2165
Echinococcus multilocularis eukaryotic initiation factor 4A III 0.0153 0.067 0.0739
Loa Loa (eye worm) hypothetical protein 0.011 0.0456 0.0994
Echinococcus granulosus cathepsin L 0.0078 0.0299 0.0329
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0057 0.0195 0.0487
Trypanosoma cruzi major cysteine proteinase, putative 0.0078 0.0299 0.0657
Brugia malayi hypothetical protein 0.0054 0.0179 0.0375
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0078 0.0299 0.075
Echinococcus granulosus ubiquitin specific protease 41 0.0032 0.0071 0.0078
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0309 0.144 0.3646
Trypanosoma brucei PAB1-binding protein , putative 0.004 0.011 0.0625
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0094 0.0376 0.2468
Brugia malayi Papain family cysteine protease containing protein 0.0078 0.0299 0.0641
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0044 0.0126 0.0726
Onchocerca volvulus 0.0072 0.0267 0.065
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0032 0.0071 0.0078
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0154 0.0674 0.4671
Brugia malayi CXXC zinc finger family protein 0.0078 0.0296 0.0635
Schistosoma mansoni calpain-7 (C02 family) 0.0049 0.0152 0.0167
Echinococcus multilocularis calpain 0.0044 0.0126 0.0139
Schistosoma mansoni cercarial elastase (S01 family) 0.0054 0.0179 0.0198
Schistosoma mansoni cercarial elastase (S01 family) 0.0054 0.0179 0.0198
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0078 0.0299 0.0329
Toxoplasma gondii preprocathepsin c precursor, putative 0.0078 0.0299 0.1812
Loa Loa (eye worm) hypothetical protein 0.0078 0.0299 0.0643
Brugia malayi Cathepsin L-like cysteine proteinase 0.0215 0.0977 0.2152
Trypanosoma brucei trypanothione reductase 0.0041 0.0114 0.0652
Plasmodium vivax ataxin-2 like protein, putative 0.004 0.011 0.0584
Entamoeba histolytica hypothetical protein 0.006 0.0207 0.1416
Leishmania major trypanothione reductase 0.0041 0.0114 0.0698
Loa Loa (eye worm) hypothetical protein 0.0037 0.0092 0.0183
Schistosoma mansoni inositol monophosphatase 0.0194 0.087 0.0959
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0309 0.144 1
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0023 0.0025 0.0027
Plasmodium falciparum serine repeat antigen 9 0.0078 0.0299 0.1936
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0054 0.0179 0.0375
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0003
Brugia malayi glutathione reductase 0.0041 0.0114 0.023
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0309 0.144 0.3646
Loa Loa (eye worm) heterotrimeric G protein alpha subunit 0.002 0.0011 0.0003
Plasmodium falciparum serine repeat antigen 7 0.0078 0.0299 0.1936
Entamoeba histolytica cysteine protease, putative 0.0172 0.0761 0.5277
Giardia lamblia Cathepsin L-like protease 0.0078 0.0299 0.1812
Loa Loa (eye worm) hypothetical protein 0.0149 0.0649 0.1423
Echinococcus granulosus cathepsin L cysteine protease 0.0172 0.0761 0.0839
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0003
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0044 0.0126 0.0274
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0078 0.0299 0.187
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0473 0.2252 0.2482
Schistosoma mansoni transcription factor LCR-F1 0.006 0.0207 0.0228
Onchocerca volvulus Cathepsin L homolog 0.0078 0.0299 0.0731
Entamoeba histolytica cysteine proteinase, putative 0.0172 0.0761 0.5277
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0094 0.0376 0.0365
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0054 0.0179 0.0198
Schistosoma mansoni cathepsin B (C01 family) 0.0078 0.0299 0.0329
Trypanosoma brucei kinesin, putative 0.003 0.0061 0.0317
Giardia lamblia Cathepsin L-like protease 0.0078 0.0299 0.1812
Echinococcus multilocularis cathepsin b 0.0927 0.4503 0.4963
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0118 0.0494 0.0544
Mycobacterium tuberculosis Probable cold-shock DeaD-box protein A homolog DeaD (ATP-dependent RNA helicase dead homolog) 0.0153 0.067 0.066
Trypanosoma cruzi inositol polyphosphate 1-phosphatase, putative 0.002 0.0011 0.0017
Echinococcus multilocularis neutral alpha glucosidase AB 0.0154 0.0674 0.0743
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0309 0.144 0.3646
Echinococcus granulosus importin subunit beta 1 0.0023 0.0025 0.0027
Plasmodium falciparum serine repeat antigen 2 0.0078 0.0299 0.1936
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0078 0.0299 0.1812
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0153 0.067 0.1693
Loa Loa (eye worm) hypothetical protein 0.0078 0.0299 0.0643
Trichomonas vaginalis inositol monophosphatase, putative 0.002 0.0011 0.002
Onchocerca volvulus 0.0054 0.0179 0.0428
Echinococcus granulosus lysosomal alpha glucosidase 0.0695 0.3354 0.3696
Loa Loa (eye worm) hypothetical protein 0.0054 0.0179 0.0378
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0073 0.0272 0.1691
Echinococcus multilocularis gtp binding protein (I) alpha 1subunit 0.002 0.0011 0.0012
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0032 0.0071 0.0376
Schistosoma mansoni cercarial elastase (S01 family) 0.0054 0.0179 0.0198
Plasmodium vivax serine-repeat antigen (SERA) 0.0078 0.0299 0.187
Brugia malayi calpain 7 0.0044 0.0126 0.0257
Echinococcus granulosus zinc finger protein 0.0026 0.0039 0.0043
Loa Loa (eye worm) fibroinase 0.0309 0.144 0.3183
Entamoeba histolytica cysteine protease, putative 0.0078 0.0299 0.2057
Schistosoma mansoni hypothetical protein 0.0617 0.2966 0.3268
Trichomonas vaginalis maltase-glucoamylase, putative 0.0154 0.0674 0.1703
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0073 0.0272 0.1646
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0078 0.0299 0.075
Plasmodium vivax SET domain protein, putative 0.0104 0.0426 0.2741
Trypanosoma cruzi trypanothione reductase, putative 0.0041 0.0114 0.0247
Brugia malayi hypothetical protein 0.0026 0.0039 0.0063
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0058 0.0198 0.0219
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0162 0.0714 0.4453
Toxoplasma gondii eukaryotic initiation factor-4A, putative 0.0153 0.067 0.4152
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0044 0.0126 0.0772
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0078 0.0299 0.075
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0054 0.0179 0.0198
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0078 0.0299 0.187
Onchocerca volvulus Eukaryotic initiation factor 4A homolog 0.0153 0.067 0.1676
Mycobacterium ulcerans beta-lactamase 0.0319 0.149 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.0019 0.0021
Giardia lamblia Translation initiation factor eIF-4A, putative 0.0153 0.067 0.4152
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0078 0.0299 0.075
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0022 0.0022 0.0024
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0309 0.144 0.3646
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0078 0.0299 0.0329
Brugia malayi cathepsin Z-like cysteine proteinase 0.0078 0.0299 0.0641
Loa Loa (eye worm) hypothetical protein 0.0195 0.0874 0.1924
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0153 0.067 0.0739
Loa Loa (eye worm) hypothetical protein 0.0046 0.0141 0.0291
Echinococcus granulosus guanine nucleotide binding protein subunit 0.002 0.0011 0.0012
Toxoplasma gondii aldehyde dehydrogenase 0.0162 0.0714 0.4426
Loa Loa (eye worm) hypothetical protein 0.0319 0.149 0.3293
Trichomonas vaginalis penicillin-binding protein, putative 0.0319 0.149 0.3771
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0309 0.144 0.3183
Entamoeba histolytica cysteine protease, putative 0.0172 0.0761 0.5277
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0473 0.2252 0.2482
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0028 0.0048 0.0053
Entamoeba histolytica hypothetical protein 0.006 0.0207 0.1416
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0103 0.042 0.0912
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0044 0.0126 0.0274
Trypanosoma brucei importin beta-1 subunit, putative 0.0023 0.0025 0.0087
Schistosoma mansoni tar DNA-binding protein 0.0103 0.042 0.0463
Plasmodium falciparum serine repeat antigen 1 0.0078 0.0299 0.1936
Entamoeba histolytica cysteine protease, putative 0.0172 0.0761 0.5277
Schistosoma mansoni survival motor neuron protein 0.004 0.0107 0.0118
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0309 0.144 0.3183
Echinococcus multilocularis calpain 7 (C02 family) 0.0044 0.0126 0.0139
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0078 0.0299 0.187
Brugia malayi Calcitonin receptor-like protein seb-1 0.0037 0.0092 0.0181
Echinococcus granulosus calpain 7 C02 family 0.0044 0.0126 0.0139
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0054 0.0179 0.0198
Onchocerca volvulus 0.0402 0.1902 0.4806
Schistosoma mansoni hypothetical protein 0.0062 0.0215 0.0237
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0247 0.1131 0.2496
Echinococcus multilocularis snurportin 1 0.0247 0.1131 0.1247
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0028 0.0048 0.0053
Entamoeba histolytica hypothetical protein 0.006 0.0207 0.1416
Brugia malayi Cathepsin L-like precursor 0.0309 0.144 0.3182
Echinococcus granulosus expressed protein 0.002 0.0011 0.0012
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0078 0.0299 0.075
Echinococcus granulosus intermediate filament protein 0.0047 0.0145 0.016
Plasmodium falciparum serine repeat antigen 8 0.0078 0.0299 0.1936
Loa Loa (eye worm) glutathione reductase 0.0041 0.0114 0.0233
Trichomonas vaginalis inositol monophosphatase, putative 0.002 0.0011 0.002
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0309 0.144 0.1587
Onchocerca volvulus 0.0095 0.038 0.0938
Brugia malayi Papain family cysteine protease containing protein 0.0172 0.0761 0.1671
Echinococcus granulosus glycoprotein Antigen 5 0.0054 0.0179 0.0198
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0473 0.2252 0.2482
Echinococcus multilocularis microtubule associated protein 2 0.185 0.9074 1
Plasmodium vivax hypothetical protein, conserved 0.0319 0.149 1
Giardia lamblia Cathepsin L precursor 0.0078 0.0299 0.1812
Trypanosoma brucei calpain-like protein, putative 0.0044 0.0126 0.0726
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0094 0.0376 0.0365
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.002 0.0011 0.0012
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0194 0.087 0.5434
Onchocerca volvulus 0.004 0.0107 0.0244
Trichomonas vaginalis GTP-binding protein (q) alpha-11 subunit, gna11, putative 0.002 0.0011 0.002
Schistosoma mansoni cercarial elastase (S01 family) 0.0054 0.0179 0.0198
Plasmodium vivax vivapain-2 0.0309 0.144 0.9663
Schistosoma mansoni cercarial elastase (S01 family) 0.0054 0.0179 0.0198
Loa Loa (eye worm) hypothetical protein 0.0054 0.0179 0.0378
Trypanosoma cruzi cysteine peptidase, putative 0.0093 0.0373 0.0822
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0078 0.0299 0.075
Echinococcus granulosus cathepsin L cysteine proteinase 0.0309 0.144 0.1587
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.002 0.0011 0.0012
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0023 0.0025 0.0027
Loa Loa (eye worm) hypothetical protein 0.0319 0.149 0.3293
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.002 0.0011 0.0012
Loa Loa (eye worm) TK/ROR protein kinase 0.0062 0.0215 0.0456
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0194 0.087 0.5
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0319 0.149 0.3293
Echinococcus granulosus dnaJ subfamily B 0.111 0.5409 0.5961
Leishmania major kinesin, putative 0.003 0.0061 0.0365
Echinococcus multilocularis Mastin 0.0054 0.0179 0.0198
Trypanosoma brucei glycosyl hydrolase-like protein 0.0057 0.0195 0.1158
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0157 0.069 0.1725
Schistosoma mansoni calpain (C02 family) 0.0044 0.0126 0.0139
Brugia malayi beta-lactamase 0.0319 0.149 0.3292
Brugia malayi Cathepsin L-like precursor 0.0093 0.0373 0.0806
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0172 0.0761 0.1924
Entamoeba histolytica cysteine protease, putative 0.0172 0.0761 0.5277
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0389 0.1835 0.4062
Loa Loa (eye worm) hypothetical protein 0.0319 0.149 0.3293
Schistosoma mansoni hypothetical protein 0.0054 0.0179 0.0198
Echinococcus granulosus cathepsin l1 0.0215 0.0977 0.1077
Toxoplasma gondii kringle domain-containing protein 0.0062 0.0215 0.1284
Loa Loa (eye worm) cysteine protease 0.0309 0.144 0.3183
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0244 0.1119 0.1233
Echinococcus granulosus lamin 0.0047 0.0145 0.016
Brugia malayi Papain family cysteine protease containing protein 0.0078 0.0299 0.0641
Echinococcus multilocularis importin subunit beta 1 0.0023 0.0025 0.0027
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0309 0.144 0.9
Plasmodium falciparum eukaryotic initiation factor 4A 0.0153 0.067 0.4561
Loa Loa (eye worm) hypothetical protein 0.0078 0.0299 0.0643
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0118 0.0494 0.0544
Loa Loa (eye worm) hypothetical protein 0.0927 0.4503 1
Trypanosoma cruzi PAB1-binding protein , putative 0.004 0.011 0.0238
Trichomonas vaginalis conserved hypothetical protein 0.0078 0.0299 0.075
Echinococcus granulosus eukaryotic initiation factor 4A 0.0153 0.067 0.0739
Loa Loa (eye worm) hypothetical protein 0.0319 0.149 0.3293
Brugia malayi N-terminal motif family protein 0.0157 0.069 0.1511
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0194 0.087 0.5412
Giardia lamblia Cysteine protease 0.0078 0.0299 0.1812
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0003
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0104 0.0428 0.0417
Loa Loa (eye worm) hypothetical protein 0.0054 0.0179 0.0378
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0172 0.0761 0.4726
Echinococcus granulosus cysteine protease 0.0172 0.0761 0.0839
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0172 0.0761 0.4726
Toxoplasma gondii cathepsin B 0.0341 0.1599 1
Schistosoma mansoni alpha glucosidase 0.0154 0.0674 0.0743
Brugia malayi Cathepsin L-like precursor 0.0215 0.0977 0.2152
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0716 0.3457 0.7671
Trypanosoma cruzi cysteine proteinase, putative 0.0172 0.0761 0.1685
Loa Loa (eye worm) hypothetical protein 0.0309 0.144 0.3183
Brugia malayi cathepsin Z-like cysteine proteinase 0.0078 0.0299 0.0641
Schistosoma mansoni intermediate filament proteins 0.0047 0.0145 0.016
Schistosoma mansoni tar DNA-binding protein 0.0103 0.042 0.0463
Brugia malayi Importin beta-1 subunit 0.0023 0.0025 0.0031
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0309 0.144 0.9
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0389 0.1835 0.4061
Mycobacterium tuberculosis Probable hydrolase 0.0319 0.149 0.148
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0154 0.0674 0.4178
Echinococcus granulosus Mastin 0.0054 0.0179 0.0198
Echinococcus multilocularis cathepsin b 0.0927 0.4503 0.4963
Brugia malayi Probable ATP-dependent helicase DHX35 0.0406 0.1923 0.4257
Brugia malayi Muscleblind-like protein 0.027 0.1247 0.2751
Schistosoma mansoni Mername-AA248 (C02 family) 0.0044 0.0126 0.0139
Mycobacterium tuberculosis Conserved protein 0.0319 0.149 0.148
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0029 0.0053 0.0058
Entamoeba histolytica cysteine protease, putative 0.0172 0.0761 0.5277
Schistosoma mansoni cpg binding protein 0.0084 0.0326 0.0359
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0695 0.3354 0.7442
Loa Loa (eye worm) hypothetical protein 0.0319 0.149 0.3293
Brugia malayi hypothetical protein 0.006 0.0207 0.0436
Onchocerca volvulus 0.0047 0.0145 0.034
Schistosoma mansoni cercarial elastase (S01 family) 0.0054 0.0179 0.0198
Loa Loa (eye worm) hypothetical protein 0.0215 0.0977 0.2154
Loa Loa (eye worm) thioredoxin reductase 0.0041 0.0114 0.0233
Mycobacterium tuberculosis Probable oxidoreductase 0.0104 0.0428 0.0417
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0319 0.149 0.1642
Echinococcus granulosus fetal alzheimer antigen falz 0.0022 0.0022 0.0024
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0153 0.067 0.1693
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0022 0.0022 0.0024
Entamoeba histolytica cysteine proteinase, putative 0.0172 0.0761 0.5277
Echinococcus granulosus inositol monophosphatase 1 0.0194 0.087 0.0959
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.1173 0.2968
Entamoeba histolytica calpain large subunit domain III containing protein 0.003 0.0061 0.0406
Echinococcus multilocularis lamin dm0 0.0047 0.0145 0.016
Mycobacterium ulcerans esterase/lipase LipP 0.0319 0.149 1
Onchocerca volvulus Cathepsin L homolog 0.0309 0.144 0.3633
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0194 0.087 0.5412
Onchocerca volvulus 0.0104 0.0426 0.1055
Echinococcus multilocularis expressed protein 0.002 0.0011 0.0012
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0078 0.0299 0.0329
Brugia malayi hypothetical protein 0.011 0.0456 0.0992
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.002 0.0011 0.002
Loa Loa (eye worm) hypothetical protein 0.0047 0.0145 0.0301
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0309 0.144 0.3646
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0078 0.0299 0.075
Schistosoma mansoni aldehyde dehydrogenase 0.0162 0.0714 0.0787
Loa Loa (eye worm) acetyltransferase 0.0244 0.1119 0.2469
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0116 0.0483 0.0532
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0153 0.067 0.1693
Brugia malayi Bromodomain containing protein 0.0037 0.0092 0.018
Trypanosoma cruzi hypothetical protein, conserved 0.0319 0.149 0.3303
Trichomonas vaginalis inositol monophosphatase, putative 0.0194 0.087 0.22
Mycobacterium tuberculosis Probable lipase LipE 0.0319 0.149 0.148
Loa Loa (eye worm) hypothetical protein 0.0093 0.0373 0.0809
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0078 0.0299 0.2057
Brugia malayi Thioredoxin reductase 0.0041 0.0114 0.023
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0172 0.0761 0.0839
Giardia lamblia Cathepsin L precursor 0.0078 0.0299 0.1812
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0044 0.0126 0.0772
Toxoplasma gondii thioredoxin reductase 0.0041 0.0114 0.0652
Onchocerca volvulus 0.0815 0.3945 1
Giardia lamblia Cathepsin L precursor 0.0078 0.0299 0.1812
Leishmania major cathepsin L-like protease 0.0309 0.144 0.9005
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0309 0.144 0.3646
Brugia malayi Cathepsin L-like precursor 0.0309 0.144 0.3182
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0044 0.0126 0.0274
Echinococcus granulosus cathepsin b 0.0927 0.4503 0.4963
Mycobacterium tuberculosis Probable dehydrogenase 0.0094 0.0376 0.0365
Entamoeba histolytica cysteine protease, putative 0.0078 0.0299 0.2057
Plasmodium falciparum serine repeat antigen 5 0.0078 0.0299 0.1936
Brugia malayi Glycosyl hydrolases family 31 protein 0.0154 0.0674 0.1477
Echinococcus granulosus calpain A 0.0121 0.0509 0.0561
Leishmania major glycosyl hydrolase-like protein 0.0057 0.0195 0.1202
Echinococcus multilocularis tar DNA binding protein 0.0103 0.042 0.0463
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.002 0.0011 0.0012
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0319 0.149 1
Trypanosoma cruzi hypothetical protein, conserved 0.0319 0.149 0.3303
Echinococcus multilocularis transmembrane protease serine 3 0.0054 0.0179 0.0198
Echinococcus granulosus beta LACTamase domain containing family member 0.0319 0.149 0.1642
Giardia lamblia Cathepsin B precursor 0.0078 0.0299 0.1812
Echinococcus multilocularis calpain family protein 1, d 0.0085 0.0332 0.0366
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0244 0.1119 0.1233
Echinococcus granulosus eukaryotic initiation factor 4A III 0.0153 0.067 0.0739
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.1173 0.2968
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0054 0.0179 0.0198
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0057 0.0195 0.0426
Trypanosoma cruzi cysteine proteinase, putative 0.0172 0.0761 0.1685
Schistosoma mansoni alpha-glucosidase 0.0598 0.2874 0.3168
Schistosoma mansoni hypothetical protein 0.0247 0.1131 0.1247
Trichomonas vaginalis G protein (olf) alpha subunit, gnal, putative 0.002 0.0011 0.002
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0078 0.0299 0.0643
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0029 0.0053 0.0058
Trypanosoma cruzi myo-inositol-1 phosphatase, putative 0.002 0.0011 0.0017
Trichomonas vaginalis alpha-glucosidase, putative 0.0057 0.0195 0.0487
Echinococcus granulosus microtubule associated protein 2 0.185 0.9074 1
Giardia lamblia Histone acetyltransferase GCN5 0.0065 0.0234 0.1402
Echinococcus granulosus gtp binding protein I alpha 1subunit 0.002 0.0011 0.0012
Brugia malayi RNA binding protein 0.0103 0.042 0.091
Leishmania major cysteine peptidase A (CPA) 0.0309 0.144 0.9005
Leishmania major cathepsin L-like protease 0.0309 0.144 0.9005
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0044 0.0126 0.0274
Schistosoma mansoni alpha-glucosidase 0.0598 0.2874 0.3168
Leishmania major inositol polyphosphate 1-phosphatase, putative 0.002 0.0011 0.0049
Plasmodium falciparum histone acetyltransferase GCN5 0.0065 0.0234 0.1476
Echinococcus granulosus thioredoxin glutathione reductase 0.0041 0.0114 0.0126
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0104 0.0428 0.0417
Schistosoma mansoni cpg binding protein 0.0084 0.0326 0.0359
Echinococcus granulosus tissue type plasminogen activator 0.0062 0.0215 0.0237
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0023 0.0024 0.0026
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0121 0.0509 0.0561
Trichomonas vaginalis glucosylceramidase, putative 0.0389 0.1835 0.4647
Plasmodium falciparum cysteine repeat modular protein 1 0.0062 0.0215 0.1344
Echinococcus granulosus lamin dm0 0.0047 0.0145 0.016
Loa Loa (eye worm) hypothetical protein 0.0116 0.0483 0.1053
Brugia malayi calpain family protein 1 0.0116 0.0483 0.105
Trichomonas vaginalis penicillin-binding protein, putative 0.0319 0.149 0.3771
Echinococcus multilocularis survival motor neuron protein 1 0.0195 0.0874 0.0963
Schistosoma mansoni cathepsin C 0.0078 0.0299 0.0329
Trypanosoma cruzi hypothetical protein, conserved 0.0154 0.0674 0.1492
Trypanosoma brucei cysteine peptidase C (CPC) 0.0341 0.1599 1
Loa Loa (eye worm) hypothetical protein 0.027 0.1247 0.2753
Loa Loa (eye worm) G protein alpha subunit 3 0.002 0.0011 0.0003
Brugia malayi Trypsin family protein 0.0054 0.0179 0.0375
Trypanosoma cruzi cruzipain precursor, putative 0.0309 0.144 0.3194
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0078 0.0299 0.0329
Echinococcus granulosus histone acetyltransferase KAT2B 0.0073 0.0272 0.03
Brugia malayi Intermediate filament tail domain containing protein 0.0047 0.0145 0.0298
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0215 0.0977 0.2472
Entamoeba histolytica cysteine proteinase 1, putative 0.0172 0.0761 0.5277
Trypanosoma cruzi cysteine peptidase, putative 0.0309 0.144 0.3194
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0309 0.144 0.9
Echinococcus granulosus neutral alpha glucosidase AB 0.0154 0.0674 0.0743
Entamoeba histolytica cysteine proteinase, putative 0.0172 0.0761 0.5277
Trypanosoma cruzi kinesin, putative 0.003 0.0061 0.013
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.002 0.0011 0.002
Onchocerca volvulus 0.0319 0.149 0.3758
Brugia malayi Inositol-1 0.0194 0.087 0.1913
Echinococcus multilocularis lysosomal alpha glucosidase 0.0695 0.3354 0.3696
Leishmania major cathepsin L-like protease 0.0309 0.144 0.9005
Toxoplasma gondii cathepsin CPC1 0.0078 0.0299 0.1812
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0309 0.144 0.9
Trichomonas vaginalis glucosylceramidase, putative 0.0389 0.1835 0.4647
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0194 0.087 0.6035
Schistosoma mansoni aldehyde dehydrogenase 0.0162 0.0714 0.0787
Schistosoma mansoni hypothetical protein 0.0054 0.0179 0.0198
Leishmania major hypothetical protein, conserved 0.0062 0.0215 0.1327
Brugia malayi follicle stimulating hormone receptor 0.0595 0.2857 0.6336
Entamoeba histolytica G protein alpha subunit, putative 0.002 0.0011 0.0055
Echinococcus multilocularis geminin 0.0617 0.2966 0.3268
Plasmodium falciparum serine repeat antigen 3 0.0078 0.0299 0.1936
Entamoeba histolytica cysteine protease, putative 0.0309 0.144 1
Giardia lamblia Encystation-specific protease 0.0078 0.0299 0.1812
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.1173 0.2968
Loa Loa (eye worm) hypothetical protein 0.0054 0.0179 0.0378
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0093 0.0373 0.0809
Loa Loa (eye worm) hypothetical protein 0.0039 0.0101 0.0204
Loa Loa (eye worm) hypothetical protein 0.0072 0.0267 0.0572
Loa Loa (eye worm) hypothetical protein 0.0093 0.0373 0.0809
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.1173 0.2968
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0341 0.1599 0.3547
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0032 0.0071 0.0078
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0078 0.0299 0.2057
Treponema pallidum ATP-dependent RNA helicase 0.0153 0.067 0.5
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0078 0.0299 0.0643
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0309 0.144 0.3646
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0054 0.0179 0.0198
Brugia malayi cathepsin L precursor 0.0078 0.0299 0.0641
Trichomonas vaginalis GTP-binding protein (O) alpha subunit, gnao, putative 0.002 0.0011 0.002
Brugia malayi Cathepsin L-like precursor 0.0215 0.0977 0.2152
Loa Loa (eye worm) hypothetical protein 0.0085 0.0332 0.0717
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0003
Trypanosoma brucei calpain-like protein, putative 0.0044 0.0126 0.0726
Echinococcus granulosus mixed lineage leukemia protein mll 0.0023 0.0025 0.0027
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0078 0.0299 0.1936
Entamoeba histolytica cysteine protease, putative 0.0172 0.0761 0.5277

Activities

Activity type Activity value Assay description Source Reference
EC50 (functional) = 70 uM Inhibition of HIV-1 replication in human peripheral blood mononuclear cells. ChEMBL. 3339606

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.