Detailed information for compound 202349

Basic information

Technical information
  • TDR Targets ID: 202349
  • Name: 2,4-dichloro-5-(4-fluorophenyl)-1-(4-methylsu lfonylphenyl)imidazole
  • MW: 385.24 | Formula: C16H11Cl2FN2O2S
  • H donors: 0 H acceptors: 3 LogP: 4.59 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: Fc1ccc(cc1)c1c(Cl)nc(n1c1ccc(cc1)S(=O)(=O)C)Cl
  • InChi: 1S/C16H11Cl2FN2O2S/c1-24(22,23)13-8-6-12(7-9-13)21-14(15(17)20-16(21)18)10-2-4-11(19)5-3-10/h2-9H,1H3
  • InChiKey: MTRLSYDWHIABRI-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2,4-dichloro-5-(4-fluorophenyl)-1-(4-mesylphenyl)imidazole

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) Starlite/ChEMBL References
Homo sapiens prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni septate junction protein 0.0021 0.0003 0.0003
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0613 0.0368 0.0368
Echinococcus multilocularis muscleblind protein 1 0.0633 0.038 0.038
Loa Loa (eye worm) hypothetical protein 0.0031 0.0009 0.0009
Mycobacterium ulcerans DNA gyrase subunit B 0.006 0.0027 0.072
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0003 0.0024
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0026 0.0035
Brugia malayi hypothetical protein 0.1483 0.0903 0.0903
Echinococcus granulosus citrate lyase subunit beta protein 0.0026 0.0006 0.0006
Echinococcus multilocularis cathepsin L cysteine protease 0.0018 0.0002 0.0002
Loa Loa (eye worm) TYRA-2 protein 0.0018 0.0001 0.0001
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0118 0.0063 0.0084
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0087 0.0044 0.0058
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0002 0.0002
Loa Loa (eye worm) cytochrome P450 family protein 0.004 0.0015 0.0015
Echinococcus granulosus ATP binding cassette sub family G 0.0021 0.0003 0.0003
Mycobacterium leprae Possible short-chain dehydrogenase EphD 0.002 0.0003 0.0024
Schistosoma mansoni smad 0.0042 0.0016 0.0016
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0352 0.0207 0.5935
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0196 0.0111 0.0111
Toxoplasma gondii cytochrome p450 superfamily protein 0.0019 0.0002 0.0001
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0003 0.0024
Brugia malayi Dopamine receptor protein 2 0.0018 0.0001 0.0001
Brugia malayi GCC2 and GCC3 family protein 0.0021 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Echinococcus granulosus microtubule associated protein 2 0.1459 0.0888 0.0888
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0013 0.0334
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0003 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0007 0.0168
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0038 0.0014 0.0014
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.002 0.0003 0.0001
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0002 0.003
Echinococcus granulosus orexin receptor type 2 0.0018 0.0001 0.0001
Mycobacterium tuberculosis Probable oxidoreductase 0.002 0.0003 0.0056
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Echinococcus multilocularis lamin 0.0057 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0127 0.0069 0.0069
Onchocerca volvulus 0.0065 0.003 0.0668
Onchocerca volvulus 0.0054 0.0024 0.0521
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.006 0.0027 0.0027
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0008 0.0215
Trypanosoma brucei membrane transporter protein, putative 0.007 0.0033 0.0044
Brugia malayi nuclear receptor NHR-88 0.0077 0.0038 0.0038
Schistosoma mansoni neuropeptide receptor 0.0018 0.0001 0.0001
Schistosoma mansoni tar DNA-binding protein 0.0069 0.0033 0.0033
Plasmodium falciparum DNA repair protein REV1, putative 0.0023 0.0005 0.0003
Echinococcus multilocularis expressed protein 0.0036 0.0012 0.0012
Brugia malayi hypothetical protein 0.0067 0.0032 0.0032
Echinococcus granulosus importin subunit beta 1 0.0031 0.0009 0.0009
Echinococcus multilocularis carbonyl reductase 1 0.002 0.0003 0.0003
Leishmania major DNA topoisomerase III, putative 0.0137 0.0074 0.0099
Toxoplasma gondii oxidoreductase, putative 0.002 0.0003 0.0001
Schistosoma mansoni steroid dehydrogenase 0.002 0.0003 0.0003
Echinococcus granulosus histone acetyltransferase KAT2B 0.0596 0.0357 0.0357
Toxoplasma gondii Alpha-galactosidase 0.0031 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.0133 0.0072 0.0072
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0026 0.0006 0.0157
Brugia malayi Cytochrome P450 family protein 0.0047 0.0019 0.0019
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0019 0.0002 0.0032
Mycobacterium tuberculosis Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1 0.002 0.0003 0.0056
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0092 0.0047 0.1258
Leishmania major GTP-binding protein, putative 0.0023 0.0004 0.0005
Onchocerca volvulus Peroxidase homolog 0.0063 0.0029 0.0646
Schistosoma mansoni smad1 5 8 and 0.0042 0.0016 0.0016
Loa Loa (eye worm) cytochrome P450 family protein 0.0047 0.0019 0.0019
Echinococcus granulosus transcription factor Dp 1 0.004 0.0015 0.0015
Brugia malayi hypothetical protein 0.0019 0.0002 0.0002
Leishmania major DNA polymerase eta, putative 0.0076 0.0037 0.0049
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Brugia malayi Globin family protein 0.0027 0.0007 0.0007
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0302 0.0176 0.503
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0033 0.0044
Toxoplasma gondii carbonyl reductase 1, putative 0.002 0.0003 0.0001
Toxoplasma gondii thioredoxin reductase 0.0139 0.0076 0.0074
Loa Loa (eye worm) hypothetical protein 0.0087 0.0044 0.0044
Echinococcus multilocularis Pleckstrin G protein, interacting region 0.0018 0.0001 0.0001
Echinococcus granulosus neuropeptide Y receptor 0.0018 0.0001 0.0001
Echinococcus multilocularis FTZ F1 alpha 0.0164 0.0091 0.0091
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0065 0.003 0.003
Echinococcus multilocularis transient receptor potential cation channel 0.002 0.0003 0.0003
Echinococcus granulosus beta-adrenergic receptor kinase 0.0022 0.0004 0.0004
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0001 0.0001
Mycobacterium tuberculosis Probable oxidoreductase 0.002 0.0003 0.0056
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0048 0.002 0.0026
Brugia malayi orphan nuclear receptor NR2E1 0.0077 0.0038 0.0038
Schistosoma mansoni sex comb on midleg homolog 0.0049 0.002 0.002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0021 0.0544
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0018 0.0001 0.0001
Mycobacterium leprae Probable UDP-galactopyranose mutase Glf (UDP-galp mutase) (NAD+-flavin adenine dinucleotide-requiring enzyme) 0.0581 0.0348 1
Schistosoma mansoni DNA topoisomerase type I 1.2096 0.7437 0.7437
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0087 0.0044 0.0044
Echinococcus multilocularis conserved hypothetical protein 0.002 0.0003 0.0003
Brugia malayi jmjC domain containing protein 0.0043 0.0017 0.0017
Schistosoma mansoni amine GPCR 0.0018 0.0001 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0092 0.0047 0.1258
Plasmodium vivax DNA repair protein REV1, putative 0.0023 0.0005 0.0003
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0002 0.0002
Schistosoma mansoni survival motor neuron protein 0.0302 0.0176 0.0176
Schistosoma mansoni ferritin 0.0036 0.0012 0.0012
Trypanosoma cruzi PAB1-binding protein , putative 0.0133 0.0072 0.0097
Loa Loa (eye worm) hypothetical protein 0.0063 0.0029 0.0029
Toxoplasma gondii isocitrate dehydrogenase 0.0098 0.0051 0.0049
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0018 0.0002 0.003
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0049 0.0021 0.0027
Loa Loa (eye worm) hypothetical protein 0.002 0.0003 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0008 0.021
Entamoeba histolytica hypothetical protein 0.0021 0.0003 0.0044
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0618 0.0371 1
Schistosoma mansoni ATP-binding cassette sub-family g2 (white protein) (abcg2) 0.0021 0.0003 0.0003
Onchocerca volvulus 0.002 0.0003 0.0062
Brugia malayi Bromodomain containing protein 0.0044 0.0018 0.0018
Schistosoma mansoni jun-related protein 0.007 0.0033 0.0033
Echinococcus multilocularis neurogenic locus notch protein 0.0021 0.0003 0.0003
Echinococcus granulosus Protein patched homolog 1 0.0043 0.0017 0.0017
Brugia malayi RNA recognition motif domain containing protein 0.0069 0.0033 0.0033
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0021 0.0003 0.0003
Echinococcus multilocularis ATP binding cassette sub family G 0.0021 0.0003 0.0003
Onchocerca volvulus 0.0018 0.0001 0.0032
Loa Loa (eye worm) thioredoxin reductase 0.0139 0.0076 0.0076
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0003 0.0003
Onchocerca volvulus Globin homolog 0.0027 0.0007 0.0151
Echinococcus granulosus hypothetical protein 0.0774 0.0467 0.0467
Echinococcus granulosus nuclear factor of activated T cells 5 0.0081 0.004 0.004
Trichomonas vaginalis alpha-glucosidase, putative 0.005 0.0021 0.0549
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0217 0.0124 0.0124
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.005 0.0021 0.0021
Brugia malayi Cathepsin L-like precursor 0.0018 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0038 0.0014 0.0014
Brugia malayi sulfakinin receptor protein 0.0018 0.0001 0.0001
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0077 0.0038 0.0038
Echinococcus granulosus expressed conserved protein 0.0094 0.0048 0.0048
Entamoeba histolytica short chain dehydrogenase family protein 0.002 0.0003 0.0033
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0008 0.0215
Schistosoma mansoni notch 0.0021 0.0003 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0003 0.0075
Leishmania major quinonoid dihydropteridine reductase 0.002 0.0003 0.0003
Trichomonas vaginalis alpha-glucosidase, putative 0.0018 0.0002 0.0032
Schistosoma mansoni intermediate filament proteins 0.0057 0.0025 0.0025
Plasmodium falciparum glutathione reductase 0.0048 0.002 0.0018
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0002 0.003
Schistosoma mansoni aldehyde dehydrogenase 0.0192 0.0109 0.0109
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0018 0.0001 0.0001
Brugia malayi hypothetical protein 0.0018 0.0001 0.0001
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0018 0.0001 0.0001
Echinococcus multilocularis neurogenic locus notch protein 0.0021 0.0003 0.0003
Echinococcus granulosus steroid dehydrogenase 0.002 0.0003 0.0003
Loa Loa (eye worm) histone methyltransferase 0.0021 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0021 0.0003 0.0003
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0077 0.0038 0.0834
Trypanosoma cruzi quinonoid dihydropteridine reductase, putative 0.002 0.0003 0.0003
Plasmodium falciparum phd finger protein, putative 0.0029 0.0008 0.0007
Echinococcus multilocularis lysosomal alpha glucosidase 0.0162 0.009 0.009
Schistosoma mansoni biogenic amine receptor 0.0018 0.0001 0.0001
Mycobacterium ulcerans DNA topoisomerase I 0.0262 0.0152 0.4328
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.002 0.0003 0.0003
Echinococcus multilocularis neuropeptides capa receptor 0.0018 0.0001 0.0001
Echinococcus granulosus neurogenic locus notch protein 0.0021 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0021 0.0003 0.0003
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0446 0.0265 0.0265
Schistosoma mansoni amine GPCR 0.0018 0.0001 0.0001
Echinococcus granulosus geminin 0.1244 0.0756 0.0756
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0049 0.0021 0.0027
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.002 0.0003 0.0001
Mycobacterium tuberculosis Conserved hypothetical protein 0.0075 0.0036 0.1016
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0039 0.0014 0.0019
Echinococcus multilocularis somatostatin receptor 0.0018 0.0001 0.0001
Schistosoma mansoni short chain dehydrogenase 0.002 0.0003 0.0003
Echinococcus multilocularis muscleblind protein 0.0633 0.038 0.038
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0018 0.0002 0.0002
Onchocerca volvulus 0.002 0.0003 0.0062
Loa Loa (eye worm) hypothetical protein 0.0027 0.0007 0.0007
Schistosoma mansoni nuclear receptor 0.0077 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Schistosoma mansoni inositol monophosphatase 0.0118 0.0063 0.0063
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.002 0.0003 0.0003
Brugia malayi CXXC zinc finger family protein 0.006 0.0027 0.0027
Echinococcus multilocularis neurogenic locus protein delta 0.0021 0.0003 0.0003
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.002 0.0003 0.0003
Trypanosoma cruzi hypothetical protein, conserved 0.007 0.0033 0.0044
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0317 0.0185 0.5308
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0017 0.0001 0.0011
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0049 0.002 0.0447
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0003 0.0024
Trichomonas vaginalis hydroxyacyl dehydrogenase, putative 0.002 0.0003 0.0064
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0164 0.0091 0.0091
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0189 0.0106 0.3018
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0118 0.0063 0.1691
Echinococcus multilocularis Multi antimicrobial extrusion protein MatE 0.0064 0.003 0.003
Plasmodium vivax hypothetical protein, conserved 0.0092 0.0047 0.0045
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0003 0.0003
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0014 0.0018
Trichomonas vaginalis sucrase-isomaltase, putative 0.005 0.0021 0.0549
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0003 0.0024
Brugia malayi acetyltransferase, GNAT family protein 0.0613 0.0368 0.0368
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.005 0.0021 0.052
Loa Loa (eye worm) hypothetical protein 0.0077 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0063 0.0029 0.0029
Echinococcus multilocularis carbonyl reductase 1 0.002 0.0003 0.0003
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0043 0.0017 0.0017
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0069 0.0033 0.0033
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0101 0.0052 0.1372
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0065 0.003 0.003
Trypanosoma cruzi metacaspase, putative 0.0092 0.0047 0.0063
Echinococcus multilocularis cysteine protease 0.0018 0.0002 0.0002
Echinococcus multilocularis microtubule associated protein 2 0.1459 0.0888 0.0888
Leishmania major hypothetical protein, conserved 0.007 0.0033 0.0044
Brugia malayi Melatonin receptor type 1A 0.0018 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0063 0.0029 0.0029
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0008 0.0007
Onchocerca volvulus 0.0027 0.0007 0.0151
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0087 0.0044 0.0058
Echinococcus multilocularis dna polymerase eta 0.0127 0.0069 0.0069
Loa Loa (eye worm) CYP4Cod1 0.0047 0.0019 0.0019
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0118 0.0063 0.0084
Schistosoma mansoni nuclear hormone receptor 0.0077 0.0038 0.0038
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0327 0.0192 0.0192
Schistosoma mansoni hypothetical protein 0.0019 0.0002 0.0002
Echinococcus multilocularis expressed conserved protein 0.0094 0.0048 0.0048
Loa Loa (eye worm) hypothetical protein 0.0063 0.0029 0.0029
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0164 0.0091 0.2006
Schistosoma mansoni carbonyl reductase 0.002 0.0003 0.0003
Brugia malayi Delta serrate ligand family protein 0.0021 0.0003 0.0003
Wolbachia endosymbiont of Brugia malayi Short-chain alcohol dehydrogenase family enzyme 0.002 0.0003 0.0039
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0048 0.002 0.0026
Onchocerca volvulus Huntingtin homolog 0.0388 0.0229 0.5038
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.006 0.0027 0.0592
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0019 0.0002 0.0043
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0002 0.003
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0021 0.0003 0.0028
Echinococcus granulosus regulator of G protein signaling 3 0.0021 0.0003 0.0003
Leishmania major short chain dehydrogenase, putative 0.002 0.0003 0.0003
Trypanosoma brucei importin beta-1 subunit, putative 0.0031 0.0009 0.0012
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0026 0.0006 0.0125
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.005 0.0021 0.0021
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0164 0.0091 0.0091
Onchocerca volvulus 0.0018 0.0001 0.0032
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0302 0.0176 0.0176
Schistosoma mansoni peroxidasin 0.0064 0.003 0.003
Echinococcus multilocularis mothers against decapentaplegic 6 0.0019 0.0002 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0002 0.003
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0018 0.0001 0.0001
Plasmodium falciparum importin beta, putative 0.0031 0.0009 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0007 0.0167
Schistosoma mansoni thyroid hormone receptor 0.0164 0.0091 0.0091
Plasmodium falciparum oxidoreductase, short-chain dehydrogenase family, putative 0.002 0.0003 0.0001
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0302 0.0176 0.503
Onchocerca volvulus 0.0164 0.0091 0.2006
Toxoplasma gondii exonuclease III APE 0.0019 0.0002 0.0001
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0098 0.0051 0.0051
Onchocerca volvulus 0.0027 0.0007 0.0151
Onchocerca volvulus 0.002 0.0003 0.0062
Loa Loa (eye worm) hypothetical protein 0.0077 0.0038 0.0038
Trypanosoma brucei 3-ketoacyl-CoA reductase, putative 0.002 0.0003 0.0003
Plasmodium vivax DNA gyrase subunit B, putative 0.006 0.0027 0.0025
Leishmania major glycosyl hydrolase-like protein 0.0018 0.0002 0.0002
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0048 0.002 0.0026
Echinococcus granulosus inositol monophosphatase 1 0.0118 0.0063 0.0063
Trypanosoma brucei metacaspase 0.0092 0.0047 0.0063
Trichomonas vaginalis glucosylceramidase, putative 0.0196 0.0111 0.298
Trypanosoma cruzi polo-like protein kinase, putative 0.0197 0.0112 0.015
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0002 0.003
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0014 0.0353
Echinococcus granulosus peregrin 0.0044 0.0018 0.0018
Brugia malayi Animal haem peroxidase family protein 0.0063 0.0029 0.0029
Echinococcus granulosus histone acetyltransferase MYST2 0.0055 0.0024 0.0024
Loa Loa (eye worm) isocitrate dehydrogenase 0.0098 0.0051 0.0051
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0048 0.002 0.0026
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0013 0.0334
Echinococcus granulosus GTP binding nuclear protein Ran 0.0023 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.002 0.0003 0.0003
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0189 0.0106 0.0106
Echinococcus granulosus cathepsin l cysteine peptidase 0.0018 0.0002 0.0002
Brugia malayi Cadherin domain containing protein 0.0021 0.0003 0.0003
Mycobacterium ulcerans ketoacyl reductase 0.002 0.0003 0.0024
Echinococcus granulosus lamin 0.0057 0.0025 0.0025
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.006 0.0027 0.0673
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0086 0.0043 0.0043
Brugia malayi bZIP transcription factor family protein 0.0086 0.0043 0.0043
Schistosoma mansoni nuclear receptor nhr-48 0.0077 0.0038 0.0038
Brugia malayi regulator of G-protein signaling egl-10 0.0039 0.0014 0.0014
Schistosoma mansoni single-minded 0.031 0.0181 0.0181
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0003 0.0003
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0105 0.0055 0.0055
Schistosoma mansoni hypothetical protein 0.0042 0.0016 0.0016
Schistosoma mansoni protein phosphatase 2C 0.0043 0.0017 0.0017
Brugia malayi PXA domain containing protein 0.0021 0.0003 0.0003
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0051 0.1354
Loa Loa (eye worm) hypothetical protein 0.0027 0.0007 0.0007
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.002 0.0003 0.0003
Schistosoma mansoni steroid dehydrogenase 0.002 0.0003 0.0003
Loa Loa (eye worm) oxidoreductase 0.002 0.0003 0.0003
Brugia malayi Animal haem peroxidase family protein 0.0063 0.0029 0.0029
Giardia lamblia DINP protein human, muc B family 0.0081 0.004 0.1039
Leishmania major hypothetical protein, conserved 0.002 0.0003 0.0003
Brugia malayi EGF-like domain containing protein 0.0021 0.0003 0.0003
Onchocerca volvulus Glucosylceramidase homolog 0.0186 0.0105 0.2301
Onchocerca volvulus 0.0018 0.0001 0.0032
Schistosoma mansoni fyve finger-containing phosphoinositide kinase fyv1 0.0018 0.0001 0.0001
Onchocerca volvulus 0.0018 0.0001 0.0032
Brugia malayi RNA, U transporter 1 0.0087 0.0044 0.0044
Brugia malayi hypothetical protein 0.0021 0.0003 0.0003
Trichomonas vaginalis prokaryotic DNA topoisomerase, putative 0.0262 0.0152 0.4088
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0098 0.0051 0.0051
Trypanosoma brucei short-chain dehydrogenase, putative 0.002 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0164 0.0091 0.0091
Echinococcus multilocularis aryl hydrocarbon receptor 0.0105 0.0055 0.0055
Loa Loa (eye worm) jmjC domain-containing protein 0.0164 0.0091 0.0091
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0004 0.0004
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0018 0.0001 0.0001
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0048 0.002 0.002
Echinococcus granulosus expressed protein 0.0409 0.0242 0.0242
Leishmania major cysteine peptidase A (CPA) 0.0018 0.0002 0.0002
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0017 0.0001 0.0001
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.005 0.0021 0.0021
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.005 0.0021 0.0021
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0028 0.0007 0.0007
Schistosoma mansoni phd/f-box containing protein 0.0043 0.0017 0.0017
Schistosoma mansoni lamin 0.0057 0.0025 0.0025
Schistosoma mansoni phosphatidylserine receptor 0.0043 0.0017 0.0017
Echinococcus multilocularis lysine specific demethylase 6a 0.0043 0.0017 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.0092 0.0047 0.1258
Echinococcus granulosus hypothetical protein 0.002 0.0003 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0014 0.0377
Onchocerca volvulus 0.0018 0.0002 0.0035
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0021 0.0003 0.0003
Trypanosoma cruzi DNA topoisomerase III, putative 0.027 0.0156 0.021
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0003 0.0024
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.002 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.0018 0.0001 0.0001
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0048 0.002 0.1004
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0023 0.0004 0.0004
Trypanosoma brucei glucosidase, putative 0.005 0.0021 0.0027
Brugia malayi MH1 domain containing protein 0.0042 0.0016 0.0016
Onchocerca volvulus 0.0021 0.0003 0.0064
Brugia malayi PXA domain containing protein 0.0021 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.0027 0.0007 0.0007
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0002 0.0001
Loa Loa (eye worm) G-protein coupled receptor 0.0018 0.0001 0.0001
Echinococcus granulosus neuropeptide s receptor 0.0018 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0021 0.0003 0.0003
Onchocerca volvulus Peroxidasin homolog 0.0063 0.0029 0.0646
Brugia malayi EGF-like domain containing protein 0.0021 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Giardia lamblia DNA topoisomerase II 0.006 0.0027 0.0673
Brugia malayi dehydrogenases, short chain protein 9 0.002 0.0003 0.0003
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0019 0.0002 0.0002
Trichomonas vaginalis guanylate cyclase, putative 0.0087 0.0044 0.1166
Brugia malayi glutathione reductase 0.0139 0.0076 0.0076
Plasmodium vivax DNA topoisomerase 3, putative 0.0262 0.0152 0.015
Trypanosoma cruzi DNA polymerase eta, putative 0.0076 0.0037 0.0049
Schistosoma mansoni hypothetical protein 0.0086 0.0043 0.0043
Brugia malayi nuclear receptor RXR 0.0087 0.0044 0.0044
Schistosoma mansoni steroid dehydrogenase 0.002 0.0003 0.0003
Schistosoma mansoni nuclear receptor 0.0077 0.0038 0.0038
Echinococcus granulosus phd:f box containing protein 0.0043 0.0017 0.0017
Loa Loa (eye worm) globin family protein 0.0027 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.002 0.0003 0.0003
Brugia malayi hypothetical protein 0.0018 0.0001 0.0001
Loa Loa (eye worm) glutathione reductase 0.0139 0.0076 0.0076
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0077 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0077 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0021 0.0003 0.0003
Loa Loa (eye worm) Smad1 0.0042 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0164 0.0091 0.0091
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0189 0.0106 0.304
Schistosoma mansoni alpha-glucosidase 0.0131 0.0071 0.0071
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0164 0.0091 0.0091
Schistosoma mansoni tar DNA-binding protein 0.0069 0.0033 0.0033
Schistosoma mansoni hypothetical protein 0.0021 0.0003 0.0003
Brugia malayi Nuclear hormone receptor E75 0.0077 0.0038 0.0038
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.002 0.0003 0.0062
Trypanosoma brucei metacaspase MCA3 0.0092 0.0047 0.0063
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.006 0.0027 0.0036
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0018 0.0001 0.0001
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0038 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0083 0.0042 0.0042
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0038 0.0014 0.0309
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0002 0.0002
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0003 0.0003
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0046 0.0019 0.0019
Brugia malayi Dopamine receptor protein 1 0.0018 0.0001 0.0001
Mycobacterium ulcerans short-chain dehydrogenase 0.002 0.0003 0.0024
Trichomonas vaginalis glucosylceramidase, putative 0.0283 0.0165 0.4432
Echinococcus granulosus dna polymerase kappa 0.0102 0.0053 0.0053
Brugia malayi Cytochrome P450 family protein 0.0019 0.0002 0.0002
Leishmania major 3-keto-dihydrosphingosine reductase 0.002 0.0003 0.0003
Brugia malayi MH2 domain containing protein 0.0042 0.0016 0.0016
Schistosoma mansoni ferritin light chain 0.0036 0.0012 0.0012
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0049 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Brugia malayi MH1 domain containing protein 0.0023 0.0005 0.0005
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0018 0.0002 0.0032
Loa Loa (eye worm) MBCTL1 0.0055 0.0024 0.0024
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0164 0.0091 0.0091
Loa Loa (eye worm) hypothetical protein 0.0021 0.0003 0.0003
Schistosoma mansoni carbonyl reductase 0.002 0.0003 0.0003
Trypanosoma brucei unspecified product 0.0051 0.0022 0.0029
Schistosoma mansoni histamine h1 receptor 0.0018 0.0001 0.0001
Trichomonas vaginalis glucosylceramidase, putative 0.0186 0.0105 0.2813
Schistosoma mansoni hypothetical protein 0.0021 0.0003 0.0003
Brugia malayi G-protein coupled receptor 0.0018 0.0001 0.0001
Brugia malayi regulator of G-protein signaling rgs-7 0.0021 0.0003 0.0003
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0118 0.0063 0.1764
Trichomonas vaginalis glucosylceramidase, putative 0.0186 0.0105 0.2813
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.0063 0.0029 0.0029
Echinococcus multilocularis oxidoreductase 0.002 0.0003 0.0003
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0001 0.0001
Schistosoma mansoni ran 0.0023 0.0004 0.0004
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0023 0.0004 0.0003
Trichomonas vaginalis maltase-glucoamylase, putative 0.005 0.0021 0.0549
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.002 0.0003 0.0003
Onchocerca volvulus 0.0137 0.0074 0.1637
Brugia malayi hypothetical protein 0.0063 0.0029 0.0029
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0217 0.0124 0.0124
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0048 0.002 0.0548
Brugia malayi ImpB/MucB/SamB family protein 0.0127 0.0069 0.0069
Brugia malayi hypothetical protein 0.0087 0.0044 0.0044
Onchocerca volvulus 0.0018 0.0002 0.0035
Echinococcus granulosus caspase 8 0.0092 0.0047 0.0047
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0087 0.0044 0.0044
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0069 0.0033 0.0043
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0007 0.0168
Entamoeba histolytica hypothetical protein 0.0021 0.0003 0.0044
Brugia malayi hypothetical protein 0.0021 0.0003 0.0003
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.002 0.0003 0.0024
Schistosoma mansoni slit 0.0021 0.0003 0.0003
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0002 0.003
Trypanosoma cruzi hypothetical protein, conserved 0.0226 0.013 0.0174
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0003 0.0024
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.002 0.0003 0.0003
Leishmania major quinonoid dihydropteridine reductase 0.002 0.0003 0.0003
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0019 0.0002 0.0032
Echinococcus granulosus jumonji domain containing 1A 0.0043 0.0017 0.0017
Brugia malayi nuclear receptor NHR-67 0.0077 0.0038 0.0038
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0145 0.0079 0.2131
Schistosoma mansoni short chain dehydrogenase 0.002 0.0003 0.0003
Schistosoma mansoni steroid dehydrogenase 0.002 0.0003 0.0003
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0065 0.003 0.003
Echinococcus multilocularis retinol dehydrogenase 11 0.002 0.0003 0.0003
Trypanosoma cruzi cytochrome P450, putative 0.0047 0.0019 0.0025
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0033 0.0044
Echinococcus multilocularis phd:f box containing protein 0.0043 0.0017 0.0017
Echinococcus multilocularis fmrfamide receptor 0.0018 0.0001 0.0001
Brugia malayi Cytochrome P450 family protein 0.0047 0.0019 0.0019
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0007 0.0167
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0013 0.0334
Leishmania major hypothetical protein, conserved 0.0133 0.0072 0.0097
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0088 0.0044 0.0059
Giardia lamblia Reductase, putative 0.002 0.0003 0.0019
Loa Loa (eye worm) DNA topoisomerase III 0.027 0.0156 0.0156
Loa Loa (eye worm) oxidoreductase 0.002 0.0003 0.0003
Loa Loa (eye worm) pax transcription factor protein 2 0.0754 0.0455 0.0455
Onchocerca volvulus Cell death protein 3 homolog 0.0178 0.01 0.2197
Trichomonas vaginalis ferritin, putative 0.0036 0.0012 0.0321
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0002 0.0036
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0033 0.0044
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0028 0.0007 0.0007
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0217 0.0124 0.0124
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.002 0.0003 0.0024
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0092 0.0047 0.0047
Loa Loa (eye worm) oxidoreductase 0.002 0.0003 0.0003
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0033 0.0044
Loa Loa (eye worm) hypothetical protein 0.0021 0.0003 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0003 0.0075
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0098 0.0051 0.0068
Mycobacterium tuberculosis Probable oxidoreductase 0.002 0.0003 0.0056
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0005 0.0005
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0003 0.0001
Leishmania major cytochrome p450-like protein 0.0019 0.0002 0.0002
Schistosoma mansoni jumonji/arid domain-containing protein 0.0164 0.0091 0.0091
Mycobacterium ulcerans hypothetical protein 0.0026 0.0006 0.0125
Brugia malayi F/Y-rich N-terminus family protein 0.003 0.0009 0.0009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0014 0.0377
Brugia malayi Cathepsin L-like precursor 0.0018 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.0042 0.0016 0.0016
Schistosoma mansoni hypothetical protein 0.0018 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.002 0.0003 0.0056
Echinococcus multilocularis neural cadherin 0.0021 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0027 0.0007 0.0007
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0164 0.0091 0.0091
Trypanosoma brucei importin beta-1 subunit, putative 0.0031 0.0009 0.0012
Echinococcus granulosus DNA topoisomerase 3 alpha 0.027 0.0156 0.0156
Echinococcus granulosus 7TM GPCR rhodopsin 0.0018 0.0001 0.0001
Brugia malayi serine/threonine-protein kinase plk-2 0.0197 0.0112 0.0112
Trichomonas vaginalis short-chain dehydrogenase, putative 0.002 0.0003 0.0064
Onchocerca volvulus 0.002 0.0003 0.0062
Onchocerca volvulus 0.0018 0.0002 0.0035
Schistosoma mansoni amine GPCR 0.0018 0.0001 0.0001
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0048 0.002 0.0018
Trypanosoma cruzi cysteine peptidase, putative 0.007 0.0033 0.0044
Brugia malayi hypothetical protein 0.0027 0.0007 0.0007
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0036 0.0012 0.0299
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0002
Schistosoma mansoni z-protein (S1r protein) 0.0039 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Echinococcus multilocularis dnaJ subfamily B 0.0853 0.0516 0.0516
Echinococcus granulosus Niemann Pick C1 protein 0.0144 0.0079 0.0079
Echinococcus granulosus TGF beta signal transducer SmadC 0.0042 0.0016 0.0016
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.002 0.0003 0.0024
Trichomonas vaginalis mercuric reductase, putative 0.0048 0.002 0.0525
Loa Loa (eye worm) jmjC domain-containing protein 0.0061 0.0028 0.0028
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0036 0.0012 0.033
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0026 0.0006 0.0125
Echinococcus granulosus Niemann Pick C1 protein 0.0101 0.0052 0.0052
Mycobacterium leprae ROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE 0.002 0.0003 0.0024
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.0008 0.0008
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.002 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0021 0.0003 0.0003
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0164 0.0091 0.0091
Schistosoma mansoni steroid dehydrogenase 0.002 0.0003 0.0003
Echinococcus multilocularis allatostatin A receptor 0.0018 0.0001 0.0001
Echinococcus multilocularis protein jagged 2 0.0021 0.0003 0.0003
Echinococcus multilocularis peregrin 0.0044 0.0018 0.0018
Mycobacterium ulcerans carveol-like dehydrogenase 0.002 0.0003 0.0024
Schistosoma mansoni notch 0.0021 0.0003 0.0003
Schistosoma mansoni jumonji domain containing protein 0.0043 0.0017 0.0017
Leishmania major ATP-binding cassette protein subfamily G, member 4, putative 0.0021 0.0003 0.0003
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0197 0.0112 0.015
Echinococcus granulosus sterol regulatory element binding protein 0.0043 0.0017 0.0017
Echinococcus multilocularis serotonin receptor 0.0018 0.0001 0.0001
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0003 0.0003
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0018 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0021 0.0003 0.0003
Echinococcus granulosus zinc finger protein 0.0018 0.0002 0.0002
Schistosoma mansoni aryl hydrocarbon receptor 0.031 0.0181 0.0181
Schistosoma mansoni hypothetical protein 0.0029 0.0008 0.0008
Schistosoma mansoni lamin 0.0057 0.0025 0.0025
Loa Loa (eye worm) animal heme peroxidase 0.0063 0.0029 0.0029
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.002 0.0003 0.0024
Loa Loa (eye worm) DNA topoisomerase III beta-1 0.0137 0.0074 0.0074
Toxoplasma gondii SWI2/SNF2-containing protein 0.0044 0.0018 0.0016
Trypanosoma cruzi metacaspase, putative 0.0092 0.0047 0.0063
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0018 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0043 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0021 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0002
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0087 0.0044 0.0044
Brugia malayi hypothetical protein 0.0018 0.0001 0.0001
Brugia malayi hypothetical protein 0.0018 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Echinococcus multilocularis isocitrate dehydrogenase 0.0098 0.0051 0.0051
Brugia malayi Serotonin receptor 0.0018 0.0001 0.0001
Echinococcus granulosus somatostatin receptor 0.0018 0.0001 0.0001
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0019 0.0002 0.0032
Leishmania major cathepsin L-like protease 0.0018 0.0002 0.0002
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0065 0.003 0.0029
Mycobacterium ulcerans aldehyde dehydrogenase 0.0192 0.0109 0.308
Trichomonas vaginalis alpha-glucosidase, putative 0.0018 0.0002 0.0032
Schistosoma mansoni ran 0.0023 0.0004 0.0004
Echinococcus granulosus jumonji domain containing protein 0.0041 0.0015 0.0015
Onchocerca volvulus DNA topoisomerase 2 homolog 0.006 0.0027 0.0592
Entamoeba histolytica Flap nuclease, putative 0.0028 0.0008 0.0168
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0018 0.0001 0.0001
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0086 0.0043 0.0043
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0048 0.002 0.0026
Brugia malayi DNA topoisomerase III beta-1 0.0137 0.0074 0.0074
Echinococcus multilocularis regulator of G protein signaling 7 0.0039 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0388 0.0229 0.0229
Giardia lamblia DNA damage repair protein 0.0023 0.0005 0.0065
Brugia malayi hypothetical protein 0.0018 0.0001 0.0001
Onchocerca volvulus Putative cubilin 0.0021 0.0003 0.0064
Brugia malayi Dehydrogenases, short chain protein 2 0.002 0.0003 0.0003
Echinococcus multilocularis g protein coupled receptor 0.0018 0.0001 0.0001
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0018 0.0001 0.0001
Schistosoma mansoni transcription factor LCR-F1 0.03 0.0175 0.0175
Trypanosoma cruzi hypothetical protein, conserved 0.007 0.0033 0.0044
Leishmania major cytochrome p450-like protein 0.0047 0.0019 0.0025
Brugia malayi RE15519p 0.0018 0.0001 0.0001
Echinococcus multilocularis caspase 8 0.0092 0.0047 0.0047
Onchocerca volvulus 0.0018 0.0001 0.0032
Brugia malayi Probable DNA topoisomerase II 0.006 0.0027 0.0027
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0003 0.0024
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.002 0.0003 0.0056
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0048 0.002 0.0517
Mycobacterium ulcerans UDP-galactopyranose mutase Glf 0.0581 0.0348 1
Loa Loa (eye worm) inositol-1 0.0118 0.0063 0.0063
Brugia malayi Animal haem peroxidase family protein 0.0063 0.0029 0.0029
Trichomonas vaginalis adenylate cyclase, putative 0.0087 0.0044 0.1166
Brugia malayi Calcium binding EGF domain containing protein 0.0021 0.0003 0.0003
Trypanosoma brucei trypanothione reductase 0.0139 0.0076 0.0101
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0092 0.0047 0.1258
Loa Loa (eye worm) MH2 domain-containing protein 0.0019 0.0002 0.0002
Echinococcus granulosus Pleckstrin G protein interacting region 0.0018 0.0001 0.0001
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0003 0.0001
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0001 0.0001
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0014 0.0353
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0118 0.0063 0.3441
Loa Loa (eye worm) hypothetical protein 0.0164 0.0091 0.0091
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0023 0.0005 0.0006
Plasmodium vivax hypothetical protein, conserved 0.002 0.0003 0.0001
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0019 0.0002 0.0032
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0196 0.0111 0.0111
Trichomonas vaginalis short-chain dehydrogenase, putative 0.002 0.0003 0.0064
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0197 0.0112 0.0112
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0087 0.0044 0.0044
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0061 0.0028 0.0028
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0049 0.0021 0.0027
Trypanosoma brucei short-chain dehydrogenase, putative 0.002 0.0003 0.0003
Brugia malayi PHD-finger family protein 0.0018 0.0002 0.0002
Echinococcus granulosus oxidoreductase 0.002 0.0003 0.0003
Trichomonas vaginalis short-chain dehydrogenase, putative 0.002 0.0003 0.0064
Loa Loa (eye worm) oxidoreductase 0.002 0.0003 0.0003
Leishmania major cathepsin L-like protease 0.0018 0.0002 0.0002
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0087 0.0044 0.1166
Trypanosoma cruzi DNA topoisomerase IB, large subunit, putative 1.2096 0.7437 1
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0019 0.0002 0.0002
Entamoeba histolytica hypothetical protein 0.03 0.0175 0.4701
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.002 0.0003 0.0024
Brugia malayi hypothetical protein 0.0388 0.0229 0.0229
Brugia malayi notch-like transmembrane receptor 0.0021 0.0003 0.0003
Mycobacterium ulcerans hypothetical protein 0.0023 0.0005 0.0073
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0221 0.0127 0.0127
Schistosoma mansoni zinc finger protein 0.0077 0.0038 0.0038
Loa Loa (eye worm) G-protein coupled receptor 0.0018 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Trypanosoma brucei beta-ketoacyl-ACP reductase 2 0.002 0.0003 0.0003
Mycobacterium ulcerans aldehyde dehydrogenase 0.0192 0.0109 0.308
Leishmania major hypothetical protein, conserved 0.002 0.0003 0.0003
Leishmania major DNA polymerase kappa, putative 0.0081 0.004 0.0054
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.005 0.0021 0.0549
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0049 0.0021 0.0515
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.005 0.0021 0.0021
Echinococcus multilocularis ATP binding cassette sub family G 0.0021 0.0003 0.0003
Echinococcus granulosus histone lysine methyltransferase setb 0.0065 0.003 0.003
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0003 0.0024
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0368 0.0217 0.4775
Schistosoma mansoni opsin-like receptor 0.0018 0.0001 0.0001
Echinococcus multilocularis g protein coupled receptor 0.0018 0.0001 0.0001
Echinococcus granulosus neuropeptide receptor 0.0018 0.0001 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0087 0.0044 0.1166
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.002 0.0003 0.0003
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.002 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Schistosoma mansoni short chain dehydrogenase 0.002 0.0003 0.0003
Schistosoma mansoni cellular tumor antigen P53 0.0054 0.0024 0.0024
Toxoplasma gondii DNA topoisomerase domain-containing protein 0.0181 0.0102 0.01
Entamoeba histolytica DNA topoisomerase II, putative 0.006 0.0027 0.0687
Onchocerca volvulus 0.0018 0.0001 0.0032
Loa Loa (eye worm) hypothetical protein 0.0077 0.0038 0.0038
Trypanosoma brucei DNA damage repair protein, putative 0.0023 0.0005 0.0005
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0077 0.0038 0.0834
Brugia malayi Inositol-1 0.0118 0.0063 0.0063
Loa Loa (eye worm) dehydrogenase 0.002 0.0003 0.0003
Loa Loa (eye worm) notch protein 0.0021 0.0003 0.0003
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0018 0.0001 0.0001
Mycobacterium tuberculosis Probable shortchain dehydrogenase 0.002 0.0003 0.0056
Onchocerca volvulus 0.0754 0.0455 1
Schistosoma mansoni laminin gamma-3 chain 0.0021 0.0003 0.0003
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0023 0.0005 0.0003
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0043 0.0017 0.0017
Onchocerca volvulus 0.0067 0.0032 0.0698
Mycobacterium ulcerans putative regulatory protein 0.0224 0.0128 0.3642
Brugia malayi hypothetical protein 0.0071 0.0034 0.0034
Chlamydia trachomatis DNA gyrase subunit B 0.006 0.0027 0.0441
Loa Loa (eye worm) MH1 domain-containing protein 0.0042 0.0016 0.0016
Schistosoma mansoni prokaryotic DNA topoisomerase 0.0314 0.0184 0.0184
Schistosoma mansoni caspase-7 (C14 family) 0.0244 0.014 0.014
Trichomonas vaginalis glucosylceramidase, putative 0.0196 0.0111 0.298
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0055 0.0024 0.0024
Leishmania major quinonoid dihydropteridine reductase 0.002 0.0003 0.0003
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0003 0.0024
Echinococcus multilocularis polycomb protein SCMH1 0.0049 0.002 0.002
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0023 0.0004 0.0003
Schistosoma mansoni kinase 0.0101 0.0052 0.0052
Giardia lamblia Oxidoreductase, short chain dehydrogenase/reductase family 0.002 0.0003 0.0019
Brugia malayi Peroxidasin 0.0064 0.003 0.003
Toxoplasma gondii aldehyde dehydrogenase 0.0192 0.0109 0.0107
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0048 0.002 0.0026
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0001 0.0001
Schistosoma mansoni ankyrin 23/unc44 0.0016 0.0000000022072 0.0000000022072
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0087 0.0044 0.0044
Schistosoma mansoni carbonyl reductase 0.002 0.0003 0.0003
Loa Loa (eye worm) MH2 domain-containing protein 0.0042 0.0016 0.0016
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0164 0.0091 0.0091
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0018 0.0001 0.0001
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0048 0.002 0.0026
Echinococcus granulosus cytochrome P450 2K1 0.0019 0.0002 0.0002
Mycobacterium leprae PROBABLE SHORT CHAIN ALCOHOL DEHYDROGENASE/REDUCTASE 0.002 0.0003 0.0024
Trypanosoma cruzi DNA damage repair protein, putative 0.0023 0.0005 0.0005
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0087 0.0044 0.149
Schistosoma mansoni ap endonuclease 0.0019 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Brugia malayi Glycosyl hydrolases family 31 protein 0.0162 0.009 0.009
Entamoeba histolytica tumor susceptibility gene 101 protein, putative 0.0048 0.002 0.0499
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0002 0.003
Echinococcus multilocularis orexin receptor type 2 0.0018 0.0001 0.0001
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0039 0.0014 0.0019
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0018 0.0001 0.0001
Brugia malayi Pax transcription factor protein 2 0.0754 0.0455 0.0455
Onchocerca volvulus 0.0018 0.0001 0.0032
Trypanosoma cruzi target of rapamycin kinase 3 0.0039 0.0014 0.0019
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Echinococcus multilocularis DNA topoisomerase 3 beta 1 0.0137 0.0074 0.0074
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0002 0.003
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0018 0.0001 0.0001
Toxoplasma gondii isocitrate dehydrogenase 0.0098 0.0051 0.0049
Trypanosoma cruzi DNA topoisomerase III, putative 0.027 0.0156 0.021
Brugia malayi PHD-finger family protein 0.0029 0.0008 0.0008
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0018 0.0001 0.0001
Trypanosoma cruzi short-chain dehydrogenase, putative 0.002 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0021 0.0003 0.0003
Trypanosoma cruzi cytochrome P450, putative 0.0047 0.0019 0.0025
Brugia malayi steroid hormone receptor 0.0164 0.0091 0.0091
Mycobacterium ulcerans short-chain dehydrogenase 0.002 0.0003 0.0024
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.002 0.0003 0.0003
Echinococcus granulosus neuropeptides capa receptor 0.0018 0.0001 0.0001
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0026 0.0006 0.0125
Loa Loa (eye worm) hypothetical protein 0.0077 0.0038 0.0038
Schistosoma mansoni hypothetical protein 0.0042 0.0016 0.0016
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0019 0.0002 0.0032
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.002 0.0003 0.0056
Loa Loa (eye worm) hypothetical protein 0.0021 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0027 0.0007 0.0007
Brugia malayi EGF-like domain containing protein 0.0021 0.0003 0.0003
Echinococcus granulosus protein jagged 2 0.0021 0.0003 0.0003
Loa Loa (eye worm) MH2 domain-containing protein 0.0622 0.0373 0.0373
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0164 0.0091 0.0091
Loa Loa (eye worm) hypothetical protein 0.0077 0.0038 0.0038
Schistosoma mansoni opsin-like receptor 0.0018 0.0001 0.0001
Schistosoma mansoni cpg binding protein 0.006 0.0027 0.0027
Brugia malayi nuclear receptor RXR 0.0077 0.0038 0.0038
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0016 0.0000000022072 0.0000000022072
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0021 0.0003 0.0003
Mycobacterium ulcerans oxidoreductase 0.002 0.0003 0.0024
Brugia malayi Melibiase family protein 0.0145 0.0079 0.0079
Trypanosoma cruzi hypothetical protein, conserved 0.007 0.0033 0.0044
Plasmodium falciparum thioredoxin reductase 0.0048 0.002 0.0018
Echinococcus multilocularis neuropeptide receptor A26 0.0018 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0021 0.0003 0.0003
Onchocerca volvulus 0.0302 0.0176 0.3881
Echinococcus granulosus expressed protein 0.0036 0.0012 0.0012
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0048 0.002 0.0026
Echinococcus multilocularis Smad4 0.0042 0.0016 0.0016
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0098 0.0051 0.0051
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0003 0.0024
Mycobacterium ulcerans short-chain type oxidoreductase 0.002 0.0003 0.0024
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0164 0.0091 0.0091
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0001 0.0001
Schistosoma mansoni notch 0.0021 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0077 0.0038 0.0038
Schistosoma mansoni apoferritin-2 0.0036 0.0012 0.0012
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0035 0.0012 0.0012
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0047 0.0019 0.0496
Trichomonas vaginalis conserved hypothetical protein 0.0092 0.0047 0.1258
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0019 0.0002 0.0002
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0002 0.0002
Echinococcus multilocularis tumor protein p63 0.037 0.0218 0.0218
Schistosoma mansoni short chain dehydrogenase 0.002 0.0003 0.0003
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0164 0.0091 0.0091
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0049 0.0021 0.0021
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0013 0.0334
Echinococcus multilocularis sex peptide receptor 0.0018 0.0001 0.0001
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0164 0.0091 0.0091
Loa Loa (eye worm) acetyltransferase 0.0613 0.0368 0.0368
Echinococcus multilocularis axis inhibition protein axin 0.0021 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0063 0.0029 0.0029
Mycobacterium ulcerans aldehyde dehydrogenase 0.0192 0.0109 0.308
Echinococcus granulosus thyroid hormone receptor alpha 0.0077 0.0038 0.0038
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0048 0.002 0.0517
Mycobacterium ulcerans bacterioferritin BfrA 0.0036 0.0012 0.0299
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0021 0.0003 0.0003
Entamoeba histolytica DNA topoisomerase III, putative 0.0262 0.0152 0.407
Leishmania major adenylate cyclase-like protein 0.0027 0.0007 0.0009
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0042 0.0016 0.0016
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0033 0.0044
Brugia malayi G-protein coupled receptor 0.0018 0.0001 0.0001
Giardia lamblia Flap structure-specific endonuclease 0.0028 0.0008 0.0154
Echinococcus multilocularis expressed protein 0.0409 0.0242 0.0242
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0002 0.0002
Brugia malayi AKH receptor 0.0018 0.0001 0.0001
Echinococcus multilocularis thyroid hormone receptor alpha 0.0164 0.0091 0.0091
Brugia malayi Bromodomain containing protein 0.0018 0.0002 0.0002
Schistosoma mansoni notch 0.0021 0.0003 0.0003
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0317 0.0185 0.5308
Giardia lamblia GTOR 0.0049 0.0021 0.0502
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0021 0.0003 0.0003
Trypanosoma brucei DNA polymerase kappa, putative 0.0102 0.0053 0.0071
Leishmania major cytochrome p450-like protein 0.0019 0.0002 0.0002
Echinococcus multilocularis caspase 0.0244 0.014 0.014
Entamoeba histolytica hypothetical protein, conserved 0.002 0.0003 0.0033
Schistosoma mansoni dishevelled 0.0018 0.0001 0.0001
Brugia malayi follicle stimulating hormone receptor 0.0018 0.0001 0.0001
Echinococcus multilocularis kelch ECH associated protein 1 0.0096 0.005 0.005
Echinococcus granulosus protein jagged 1 0.0021 0.0003 0.0003
Leishmania major pteridine reductase 1 0.002 0.0003 0.0003
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0018 0.0001 0.0001
Echinococcus multilocularis 0.0421 0.025 0.025
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0244 0.014 0.014
Echinococcus multilocularis tar DNA binding protein 0.0069 0.0033 0.0033
Echinococcus multilocularis Niemann Pick C1 protein 0.0101 0.0052 0.0052
Loa Loa (eye worm) mbt repeat family protein 0.0049 0.002 0.002
Brugia malayi DNA topoisomerase II, alpha isozyme 0.006 0.0027 0.0027
Schistosoma mansoni DNA topoisomerase type I 1.2096 0.7437 0.7437
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.006 0.0027 0.0027
Leishmania major DNA topoisomerase type IB small subunit 0.5675 0.3484 0.4684
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0069 0.0033 0.0033
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0002 0.003
Schistosoma mansoni serine/threonine protein kinase 0.0197 0.0112 0.0112
Toxoplasma gondii EGF family domain-containing protein 0.0021 0.0003 0.0001
Schistosoma mansoni DNA polymerase IV / kappa 0.0023 0.0005 0.0005
Trichomonas vaginalis CAMK family protein kinase 0.0197 0.0112 0.3007
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.006 0.0027 0.0036
Brugia malayi Pre-SET motif family protein 0.0446 0.0265 0.0265
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.0004 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0008 0.0215
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0048 0.002 0.0026
Echinococcus multilocularis fibropellin Ia 0.0021 0.0003 0.0003
Schistosoma mansoni neuropeptide receptor 0.0018 0.0001 0.0001
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0217 0.0124 0.0124
Echinococcus granulosus mothers against decapentaplegic 5 0.0042 0.0016 0.0016
Echinococcus multilocularis cysteine protease 0.0018 0.0002 0.0002
Trypanosoma brucei Metacaspase-4 0.0092 0.0047 0.0063
Loa Loa (eye worm) hypothetical protein 0.0026 0.0007 0.0007
Trichomonas vaginalis short-chain dehydrogenase, putative 0.002 0.0003 0.0064
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0001 0.0001
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.002 0.0003 0.0001
Mycobacterium tuberculosis Possible iron-regulated short-chain dehydrogenase/reductase 0.002 0.0003 0.0056
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0189 0.0106 0.0106
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0003 0.0075
Trypanosoma cruzi membrane transporter protein, putative 0.007 0.0033 0.0044
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0002 0.003
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0618 0.0371 1
Echinococcus multilocularis dna polymerase kappa 0.0102 0.0053 0.0053
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0043 0.0017 0.0015
Leishmania major importin beta-1 subunit, putative 0.0025 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Loa Loa (eye worm) cysteine protease 0.0018 0.0002 0.0002
Trichomonas vaginalis set domain proteins, putative 0.0507 0.0303 0.8164
Trypanosoma brucei unspecified product 0.0095 0.0049 0.0065
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Echinococcus multilocularis sterol regulatory element binding protein 0.0043 0.0017 0.0017
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0039 0.0014 0.0014
Schistosoma mansoni hypothetical protein 0.0853 0.0516 0.0516
Onchocerca volvulus 0.002 0.0003 0.0062
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0164 0.0091 0.0091
Brugia malayi MH2 domain containing protein 0.0019 0.0002 0.0002
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0018 0.0001 0.0001
Echinococcus granulosus tar DNA binding protein 0.0069 0.0033 0.0033
Brugia malayi DNA topoisomerase III 0.027 0.0156 0.0156
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0018 0.0001 0.0001
Schistosoma mansoni tar DNA-binding protein 0.0069 0.0033 0.0033
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0087 0.0044 0.1166
Brugia malayi aryl hydrocarbon receptor nuclear translocator protein, putative 0.0019 0.0002 0.0002
Schistosoma mansoni neuropeptide F-like receptor 0.0018 0.0001 0.0001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0002 0.003
Schistosoma mansoni caspase-7 (C14 family) 0.0178 0.01 0.01
Wolbachia endosymbiont of Brugia malayi topoisomerase IA, TopA 0.0307 0.0179 1
Schistosoma mansoni hypothetical protein 0.03 0.0175 0.0175
Echinococcus granulosus FTZ F1 alpha 0.0164 0.0091 0.0091
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0026 0.0006 0.0008
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.005 0.0021 0.0021
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0048 0.002 0.0026
Echinococcus granulosus lamin dm0 0.0057 0.0025 0.0025
Echinococcus multilocularis caspase 3 0.0152 0.0084 0.0084
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0003 0.0003
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0003 0.0001
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0003 0.0024
Brugia malayi mothers against decapentaplegic homolog 3 0.0019 0.0002 0.0002
Leishmania major cathepsin L-like protease 0.007 0.0033 0.0044
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.002 0.0003 0.0056
Brugia malayi Animal haem peroxidase family protein 0.0063 0.0029 0.0029
Schistosoma mansoni ferritin 0.0036 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0043 0.0017 0.0017
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0003 0.0003
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0026 0.0006 0.0158
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0018 0.0001 0.0001
Echinococcus multilocularis retinol dehydrogenase 11 0.002 0.0003 0.0003
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0023 0.0004 0.0003
Onchocerca volvulus 0.0018 0.0001 0.0032
Echinococcus multilocularis neuropeptide Y receptor 0.0018 0.0001 0.0001
Echinococcus granulosus smad 0.0042 0.0016 0.0016
Echinococcus multilocularis carbonyl reductase 1 0.002 0.0003 0.0003
Loa Loa (eye worm) DIX domain-containing protein 0.0018 0.0001 0.0001
Leishmania major cathepsin L-like protease 0.0018 0.0002 0.0002
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0003 0.0003
Onchocerca volvulus 0.002 0.0003 0.0062
Echinococcus granulosus allatostatin A receptor 0.0018 0.0001 0.0001
Echinococcus granulosus tumor susceptibility gene 101 protein 0.0071 0.0034 0.0034
Echinococcus multilocularis conserved hypothetical protein 0.0756 0.0456 0.0456
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0164 0.0091 0.0091
Loa Loa (eye worm) hypothetical protein 0.0071 0.0034 0.0034
Brugia malayi polk-prov protein 0.0051 0.0022 0.0022
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0003 0.0003
Plasmodium vivax ataxin-2 like protein, putative 0.0133 0.0072 0.0071
Trypanosoma cruzi metacaspase 5, putative 0.0092 0.0047 0.0063
Schistosoma mansoni hypothetical protein 0.1244 0.0756 0.0756
Brugia malayi ecdysteroid receptor 0.0164 0.0091 0.0091
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0192 0.0109 0.0109
Trichomonas vaginalis alpha-glucosidase, putative 0.0018 0.0002 0.0032
Brugia malayi hypothetical protein 0.0018 0.0001 0.0001
Onchocerca volvulus Protein ultraspiracle homolog 0.0164 0.0091 0.2006
Giardia lamblia DNA topoisomerase III 0.0262 0.0152 0.4062
Loa Loa (eye worm) hypothetical protein 0.0063 0.0029 0.0029
Plasmodium falciparum DNA topoisomerase 3, putative 0.0262 0.0152 0.015
Brugia malayi CHE-14 protein 0.0043 0.0017 0.0017
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0317 0.0185 0.5308
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0019 0.0002 0.0032
Toxoplasma gondii HEAT repeat-containing protein 0.0031 0.0009 0.0008
Echinococcus multilocularis jumonji domain containing protein 0.0041 0.0015 0.0015
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0002 0.003
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0002
Echinococcus granulosus regulator of G protein signaling 7 0.0039 0.0014 0.0014
Entamoeba histolytica deoxycytidyl transferase, putative 0.0075 0.0036 0.0937
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0048 0.002 0.0026
Trypanosoma cruzi oxidoreductase-like protein, putative 0.002 0.0003 0.0003
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0049 0.0021 0.0021
Leishmania major hypothetical protein, conserved 0.007 0.0033 0.0044
Trypanosoma cruzi hypothetical protein, conserved 0.005 0.0021 0.0027
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0003 0.0003
Echinococcus granulosus DNA topoisomerase 2 alpha 0.006 0.0027 0.0027
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0019 0.0002 0.0032
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.002 0.0003 0.0003
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0618 0.0371 1
Schistosoma mansoni growth hormone secretagogue receptor 0.0018 0.0001 0.0001
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0018 0.0002 0.0002
Trypanosoma cruzi PAB1-binding protein , putative 0.0133 0.0072 0.0097
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0087 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 0.0077 0.0038 0.0038
Echinococcus multilocularis retinol dehydrogenase 13 0.002 0.0003 0.0003
Brugia malayi hypothetical protein 0.0018 0.0001 0.0001
Brugia malayi Dehydrogenases, short chain protein 30 0.002 0.0003 0.0003
Echinococcus granulosus biogenic amine 5HT receptor 0.0018 0.0001 0.0001
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0164 0.0091 0.0091
Echinococcus multilocularis slit 2 protein 0.0021 0.0003 0.0003
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0174 0.0098 0.2604
Brugia malayi nuclear hormone receptor 0.0077 0.0038 0.0038
Echinococcus granulosus thioredoxin glutathione reductase 0.0139 0.0076 0.0076
Echinococcus multilocularis notch 0.0021 0.0003 0.0003
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0098 0.0051 0.0051
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Giardia lamblia Kinase, PLK 0.0197 0.0112 0.2975
Loa Loa (eye worm) hypothetical protein 0.0077 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.002 0.0003 0.0003
Entamoeba histolytica serine/threonine protein kinase, putative 0.0197 0.0112 0.2985
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0026 0.0035
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0038 0.0014 0.0014
Brugia malayi hypoxia-induced factor 1 0.0936 0.0566 0.0566
Schistosoma mansoni Smad4 0.0019 0.0002 0.0002
Brugia malayi PAS domain containing protein 0.031 0.0181 0.0181
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0001 0.0001
Mycobacterium tuberculosis Probable short-chain type oxidoreductase 0.002 0.0003 0.0056
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0018 0.0001 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0014 0.0353
Giardia lamblia Fructose-bisphosphate aldolase 0.0618 0.0371 1
Loa Loa (eye worm) hypothetical protein 0.0087 0.0044 0.0044
Schistosoma mansoni hypothetical protein 0.0018 0.0001 0.0001
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0164 0.0091 0.0091
Onchocerca volvulus 0.0086 0.0043 0.0949
Onchocerca volvulus Cathepsin L homolog 0.0018 0.0002 0.0035
Brugia malayi Hypothetical 22.2 kDa protein C28F5.2 in chromosome II, putative 0.0027 0.0007 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0087 0.0044 0.1166
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0069 0.0033 0.0033
Echinococcus granulosus multidrug and toxin extrusion protein 2 0.007 0.0033 0.0033
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0003 0.0003
Loa Loa (eye worm) neuropeptide F receptor 0.0018 0.0001 0.0001
Echinococcus granulosus ecdysone induced protein 78C 0.0164 0.0091 0.0091
Echinococcus granulosus peroxidasin 0.0064 0.003 0.003
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0005 0.0005
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0018 0.0002 0.0032
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0618 0.0371 1
Trichomonas vaginalis glutathione reductase, putative 0.0048 0.002 0.0525
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0031 0.0009 0.0009
Treponema pallidum bacterioferrin (TpF1) 0.0036 0.0012 0.0277
Plasmodium vivax ABC transporter G family member 2, putative 0.0021 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.0021 0.0003 0.0003
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0283 0.0165 0.0165
Echinococcus granulosus ubiquitin specific protease 41 0.0038 0.0014 0.0014
Echinococcus multilocularis g-protein coupled receptor 0.0018 0.0001 0.0001
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.005 0.0021 0.052
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0075 0.0036 0.0036
Trypanosoma brucei DNA topoisomerase III, putative 0.027 0.0156 0.021
Brugia malayi Globin family protein 0.0027 0.0007 0.0007
Brugia malayi Cadherin domain containing protein 0.0021 0.0003 0.0003
Trypanosoma brucei beta-D-hydroxybutyrate dehydrogenase 0.002 0.0003 0.0003
Brugia malayi GnHR receptor homolog 0.0018 0.0001 0.0001
Echinococcus granulosus Nuclear hormone receptor HR96 0.0077 0.0038 0.0038
Echinococcus granulosus fibropellin Ia 0.0021 0.0003 0.0003
Schistosoma mansoni bromodomain containing protein 0.0018 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0021 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0021 0.0003 0.0003
Loa Loa (eye worm) cytochrome P450 family protein 0.0047 0.0019 0.0019
Brugia malayi MH2 domain containing protein 0.0622 0.0373 0.0373
Brugia malayi mbt repeat family protein 0.0049 0.002 0.002
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0302 0.0176 0.0176
Loa Loa (eye worm) fibroinase 0.0018 0.0002 0.0002
Brugia malayi Intermediate filament tail domain containing protein 0.0057 0.0025 0.0025
Schistosoma mansoni opsin-like receptor 0.0018 0.0001 0.0001
Onchocerca volvulus 0.0018 0.0002 0.0035
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.0033 0.0043
Schistosoma mansoni tar DNA-binding protein 0.0069 0.0033 0.0033
Echinococcus multilocularis jumonji domain containing 1A 0.0043 0.0017 0.0017
Schistosoma mansoni caspase-3 (C14 family) 0.0244 0.014 0.014
Brugia malayi tailless protein 0.0077 0.0038 0.0038
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0081 0.004 0.0054
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0003 0.0003
Mycobacterium leprae Possible regulatory protein 0.0087 0.0044 0.1203
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0026 0.0035
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0019 0.0002 0.0032
Trypanosoma cruzi DNA topoisomerase IA, putative 0.0262 0.0152 0.0204
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0023 0.0004 0.0004
Echinococcus granulosus neurogenic locus notch protein 0.0021 0.0003 0.0003
Echinococcus granulosus nuclear receptor nhr 48 0.0077 0.0038 0.0038
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.006 0.0027 0.0027
Loa Loa (eye worm) oxidoreductase 0.002 0.0003 0.0003
Trypanosoma brucei 3-keto-dihydrosphingosine reductase 0.002 0.0003 0.0003
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0003 0.0003
Brugia malayi DIX domain containing protein 0.0018 0.0001 0.0001
Plasmodium falciparum metacaspase-like protein 0.0092 0.0047 0.0045
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Schistosoma mansoni microtubule-associated protein tau 0.1459 0.0888 0.0888
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0002 0.0002
Brugia malayi Nuclear hormone receptor-like 1 0.0087 0.0044 0.0044
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0129 0.007 0.007
Brugia malayi Cathepsin L-like precursor 0.0018 0.0002 0.0002
Schistosoma mansoni patched 1 0.0043 0.0017 0.0017
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0002 0.0001
Echinococcus multilocularis caspase 2 0.0178 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0065 0.003 0.003
Echinococcus granulosus alpha 1A adrenergic receptor 0.0018 0.0001 0.0001
Echinococcus granulosus aryl hydrocarbon receptor 0.0105 0.0055 0.0055
Trypanosoma cruzi cruzipain precursor, putative 0.007 0.0033 0.0044
Schistosoma mansoni alpha-1 adrenergic receptor 0.0018 0.0001 0.0001
Leishmania major DNA topoisomerase IB, large subunit 1.2096 0.7437 1
Leishmania major quinonoid dihydropteridine reductase 0.002 0.0003 0.0003
Leishmania major trypanothione reductase 0.0139 0.0076 0.0101
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0618 0.0371 1
Loa Loa (eye worm) dehydrogenase 0.002 0.0003 0.0003
Brugia malayi Pre-SET motif family protein 0.0065 0.003 0.003
Echinococcus granulosus neutral alpha glucosidase AB 0.005 0.0021 0.0021
Trypanosoma brucei unspecified product 0.0051 0.0022 0.0029
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0003 0.0024
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.0033 0.0043
Trypanosoma cruzi DNA polymerase eta, putative 0.0127 0.0069 0.0092
Schistosoma mansoni thyroid hormone receptor 0.0164 0.0091 0.0091
Schistosoma mansoni tar DNA-binding protein 0.0069 0.0033 0.0033
Brugia malayi G protein-coupled receptor F59B2.13 0.0018 0.0001 0.0001
Trypanosoma cruzi cysteine peptidase, putative 0.007 0.0033 0.0044
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0098 0.0051 0.0049
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0018 0.0001 0.0001
Echinococcus multilocularis JmjC domain containing protein 4 0.0043 0.0017 0.0017
Brugia malayi cytoplasmic intermediate filament protein 0.0031 0.0009 0.0009
Loa Loa (eye worm) nuclear hormone receptor 0.0077 0.0038 0.0038
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0019 0.0002 0.0032
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0003 0.0003
Echinococcus multilocularis protein jagged 1 0.0021 0.0003 0.0003
Brugia malayi nuclear hormone receptor family member nhr-6 0.0077 0.0038 0.0038
Echinococcus granulosus peptide allatostatin:somatostatin 0.0018 0.0001 0.0001
Trypanosoma cruzi short chain dehydrogenase, putative 0.002 0.0003 0.0003
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0077 0.0038 0.0038
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0018 0.0002 0.0002
Giardia lamblia DNA topoisomerase III 0.0137 0.0074 0.1962
Echinococcus granulosus slit 2 protein 0.0021 0.0003 0.0003
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.002 0.0003 0.0062
Echinococcus granulosus dnaJ subfamily B 0.0853 0.0516 0.0516
Loa Loa (eye worm) hypothetical protein 0.002 0.0003 0.0003
Schistosoma mansoni smad 0.0019 0.0002 0.0002
Schistosoma mansoni cpg binding protein 0.0063 0.0029 0.0029
Brugia malayi hypothetical protein 0.0018 0.0001 0.0001
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0168 0.0094 0.0094
Plasmodium falciparum metacaspase 1 0.0092 0.0047 0.0045
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0019 0.0002 0.0032
Loa Loa (eye worm) hypothetical protein 0.0021 0.0003 0.0003
Brugia malayi EGF-like domain containing protein 0.0021 0.0003 0.0003
Schistosoma mansoni neuropeptide receptor 0.0018 0.0001 0.0001
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.002 0.0003 0.0024
Schistosoma mansoni tsg101-related 0.0059 0.0027 0.0027
Mycobacterium tuberculosis Probable monooxygenase 0.0027 0.0007 0.0173
Brugia malayi jmjC domain containing protein 0.0221 0.0127 0.0127
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0069 0.0033 0.084
Schistosoma mansoni biogenic amine (5HT) receptor 0.0018 0.0001 0.0001
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0018 0.0001 0.0001
Schistosoma mansoni steroid dehydrogenase 0.002 0.0003 0.0003
Onchocerca volvulus 0.0018 0.0001 0.0032
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0016 0.0425
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0003 0.0024
Echinococcus multilocularis protein patched 0.0043 0.0017 0.0017
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.002 0.0003 0.0056
Schistosoma mansoni short chain dehydrogenase 0.002 0.0003 0.0003
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0049 0.002 0.002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0013 0.0334
Mycobacterium tuberculosis DNA topoisomerase I TopA (omega-protein) (relaxing enzyme) (untwisting enzyme) (swivelase) (type I DNA topoisomerase) (nicking-c 0.0126 0.0068 0.1923
Trichomonas vaginalis CAMK family protein kinase 0.0197 0.0112 0.3007
Echinococcus multilocularis protein jagged 1 0.0021 0.0003 0.0003
Mycobacterium tuberculosis Probable dehydrogenase 0.002 0.0003 0.0056
Brugia malayi ecdysone receptor 0.0077 0.0038 0.0038
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0003 0.0024
Echinococcus granulosus g-protein coupled receptor 0.0018 0.0001 0.0001
Brugia malayi MH2 domain containing protein 0.0042 0.0016 0.0016
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0189 0.0106 0.0106
Schistosoma mansoni regulator of G protein signaling 0.0039 0.0014 0.0014
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0048 0.002 0.0018
Leishmania major quinonoid dihydropteridine reductase 0.002 0.0003 0.0003
Schistosoma mansoni sex comb on midleg homolog 0.0049 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Echinococcus multilocularis fmrfamide receptor 0.0018 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0021 0.0003 0.0003
Echinococcus granulosus DNA topoisomerase 3 beta 1 0.0137 0.0074 0.0074
Echinococcus granulosus segment polarity protein dishevelled 0.0018 0.0001 0.0001
Trichomonas vaginalis importin beta-1, putative 0.0025 0.0006 0.0139
Loa Loa (eye worm) hypoxia-induced factor 1 0.0936 0.0566 0.0566
Echinococcus multilocularis Regulator of G protein signaling 20 0.0021 0.0003 0.0003
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.018 0.0101 0.01
Treponema pallidum DNA topoisomerase I (topA) 0.0307 0.0179 0.4805
Brugia malayi Steroid receptor seven-up type 2 0.0164 0.0091 0.0091
Schistosoma mansoni nuclear hormone receptor 0.0164 0.0091 0.0091
Onchocerca volvulus 0.0027 0.0007 0.0151
Loa Loa (eye worm) hypothetical protein 0.1153 0.07 0.07
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0021 0.0544
Brugia malayi Blistered cuticle protein 3 0.0063 0.0029 0.0029
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0043 0.0017 0.0022
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0075 0.0036 0.0036
Trichomonas vaginalis glucosylceramidase, putative 0.0283 0.0165 0.4432
Echinococcus multilocularis g protein coupled receptor 0.0018 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0021 0.0003 0.0003
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0001 0.0001
Onchocerca volvulus 0.006 0.0027 0.0598
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0164 0.0091 0.0091
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.0019 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0055 0.0024 0.0024
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0613 0.0368 0.0368
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0018 0.0001 0.0001
Onchocerca volvulus 0.0018 0.0001 0.0032
Echinococcus multilocularis fat cadherin tumor suppressor 0.0021 0.0003 0.0003
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 1 homolog 0.002 0.0003 0.0062
Brugia malayi Importin beta-1 subunit 0.0031 0.0009 0.0009
Brugia malayi Cathepsin L-like precursor 0.0018 0.0002 0.0002
Trypanosoma brucei metacaspase 5, putative 0.0092 0.0047 0.0063
Loa Loa (eye worm) hypothetical protein 0.0057 0.0025 0.0025
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0098 0.0051 0.0068
Brugia malayi hypothetical protein 0.0018 0.0001 0.0001
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.002 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.1483 0.0903 0.0903
Leishmania major hypothetical protein, conserved 0.002 0.0003 0.0003
Trichomonas vaginalis steroid dehydrogenase, putative 0.002 0.0003 0.0064
Plasmodium vivax SET domain protein, putative 0.0065 0.003 0.0029
Loa Loa (eye worm) hypothetical protein 0.0087 0.0044 0.0044
Brugia malayi oxidoreductase 0.002 0.0003 0.0003
Schistosoma mansoni DNA polymerase eta 0.0127 0.0069 0.0069
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0033 0.0044
Loa Loa (eye worm) nuclear receptor NHR-67 0.0077 0.0038 0.0038
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0003 0.0024
Trypanosoma cruzi DNA damage repair protein, putative 0.0023 0.0005 0.0005
Onchocerca volvulus Peroxidase homolog 0.0063 0.0029 0.0646
Trypanosoma brucei PAB1-binding protein , putative 0.0133 0.0072 0.0097
Brugia malayi neuropeptide F receptor 0.0018 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0021 0.0003 0.0003
Brugia malayi ImpB/MucB/SamB family protein 0.0075 0.0036 0.0036
Echinococcus multilocularis regulator of G protein signaling 0.0021 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0016 0.0000082487 0.0000082487
Trypanosoma brucei beta-ketoacyl-ACP reductase 3, putative 0.002 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.002 0.0003 0.0003
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0076 0.0037 0.0036
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0139 0.0076 0.2156
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0035 0.0012 0.0012
Trypanosoma cruzi DNA topoisomerase III, putative 0.0137 0.0074 0.0099
Brugia malayi Isocitrate dehydrogenase 0.0098 0.0051 0.0051
Toxoplasma gondii oxidoreductase, putative 0.002 0.0003 0.0001
Mycobacterium ulcerans ketoacyl reductase 0.002 0.0003 0.0024
Trypanosoma brucei DNA polymerase kappa, putative 0.0102 0.0053 0.0071
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0018 0.0002 0.0002
Echinococcus granulosus polycomb protein SCMH1 0.0049 0.002 0.002
Echinococcus multilocularis kelch ECH associated protein 1 0.0096 0.005 0.005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0007 0.0167
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0033 0.0044
Plasmodium falciparum DNA topoisomerase 2 0.006 0.0027 0.0025
Echinococcus multilocularis beta adrenergic receptor kinase 0.0022 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0021 0.0003 0.0003
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0018 0.0002 0.0036
Loa Loa (eye worm) hypothetical protein 0.0087 0.0044 0.0044
Leishmania major mitochondrial DNA topoisomerase II 0.006 0.0027 0.0036
Schistosoma mansoni inositol monophosphatase 0.0118 0.0063 0.0063
Brugia malayi RNA binding protein 0.0069 0.0033 0.0033
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0088 0.0044 0.0059
Schistosoma mansoni hypothetical protein 0.006 0.0027 0.0027
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.006 0.0027 0.0027
Trypanosoma cruzi importin beta-1 subunit, putative 0.0025 0.0006 0.0007
Brugia malayi hypothetical protein 0.0018 0.0001 0.0001
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0018 0.0001 0.0001
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0098 0.0051 0.1441
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0102 0.0053 0.1425
Schistosoma mansoni bromodomain containing protein 0.0018 0.0002 0.0002
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0049 0.0021 0.0027
Onchocerca volvulus 0.0057 0.0025 0.0559
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0018 0.0001 0.0001
Treponema pallidum NADH oxidase 0.0048 0.002 0.0482
Schistosoma mansoni notch 0.0021 0.0003 0.0003
Schistosoma mansoni short chain dehydrogenase 0.002 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0039 0.0014 0.0014
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0002 0.003
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0048 0.002 0.002
Leishmania major short chain dehydrogenase, putative 0.002 0.0003 0.0003
Onchocerca volvulus 0.0021 0.0003 0.0064
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0618 0.0371 1
Echinococcus granulosus neuropeptide receptor 0.0018 0.0001 0.0001
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0023 0.0004 0.0056
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.03 0.0175 0.0175
Loa Loa (eye worm) hypothetical protein 0.0021 0.0003 0.0003
Loa Loa (eye worm) oxidoreductase 0.002 0.0003 0.0003
Echinococcus granulosus tm gpcr rhodopsin 0.0018 0.0001 0.0001
Schistosoma mansoni multidrug resistance protein 0.007 0.0033 0.0033
Brugia malayi Cathepsin L-like precursor 0.0018 0.0002 0.0002
Brugia malayi Muscle positioning protein 4 0.0021 0.0003 0.0003
Echinococcus multilocularis G-protein coupled receptor, putative 0.0018 0.0001 0.0001
Entamoeba histolytica acetyltransferase, GNAT family 0.0165 0.0092 0.2451
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Echinococcus multilocularis dro:myosuppressin receptor 0.0018 0.0001 0.0001
Echinococcus granulosus SAM and MBT domain containing protein 0.0049 0.002 0.002
Echinococcus multilocularis carbonyl reductase 1 0.002 0.0003 0.0003
Loa Loa (eye worm) MH1 domain-containing protein 0.0019 0.0002 0.0002
Leishmania major protein kinase, putative 0.0088 0.0044 0.0059
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0019 0.0002 0.0032
Loa Loa (eye worm) hypothetical protein 0.0043 0.0017 0.0017
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0033 0.0044
Schistosoma mansoni short chain dehydrogenase 0.002 0.0003 0.0003
Giardia lamblia Short-chain dehydrogenase, putative 0.002 0.0003 0.0019
Loa Loa (eye worm) jmjC domain-containing protein 0.0043 0.0017 0.0017
Trypanosoma cruzi hypothetical protein, conserved 0.007 0.0033 0.0044
Loa Loa (eye worm) hypothetical protein 0.0368 0.0217 0.0217
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0018 0.0001 0.0001
Brugia malayi hypothetical protein 0.0086 0.0043 0.0043
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0049 0.0021 0.0027
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0018 0.0002 0.0002
Trichomonas vaginalis short-chain dehydrogenase, putative 0.002 0.0003 0.0064
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.3436 0.2106 0.2106
Echinococcus granulosus WW domain containing oxidoreductase 0.002 0.0003 0.0003
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.002 0.0003 0.0024
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0043 0.0017 0.0015
Schistosoma mansoni short chain dehydrogenase 0.002 0.0003 0.0003
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0077 0.0038 0.0038
Brugia malayi Cell death protein 3 precursor 0.0178 0.01 0.01
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0036 0.0012 0.033
Leishmania major DNA polymerase kappa, putative 0.0023 0.0005 0.0005
Echinococcus multilocularis Niemann Pick C1 protein 0.0144 0.0079 0.0079
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0018 0.0002 0.003
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0048 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0077 0.0038 0.0038
Trichomonas vaginalis CAMK family protein kinase 0.0197 0.0112 0.3007
Trichomonas vaginalis short-chain dehydrogenases/reductase, putative 0.002 0.0003 0.0064
Trypanosoma cruzi DNA topoisomerase IA, putative 0.0262 0.0152 0.0204
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.018 0.0101 0.2724
Brugia malayi neuropeptide F receptor 0.0018 0.0001 0.0001
Mycobacterium tuberculosis Probable oxidoreductase 0.0352 0.0207 0.5935
Trypanosoma cruzi short chain dehydrogenase, putative 0.002 0.0003 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0092 0.0047 0.1258
Leishmania major short chain dehydrogenase-like protein 0.002 0.0003 0.0003
Trypanosoma cruzi trypanothione reductase, putative 0.0139 0.0076 0.0101
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0051 0.1354
Echinococcus multilocularis segment polarity protein dishevelled 0.0018 0.0001 0.0001
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0018 0.0001 0.0001
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0002 0.0014
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0018 0.0001 0.0001
Toxoplasma gondii histone lysine methyltransferase SET1 0.0131 0.0071 0.0069
Loa Loa (eye worm) hypothetical protein 0.0164 0.0091 0.0091
Brugia malayi hypothetical protein 0.0027 0.0007 0.0007
Plasmodium falciparum glutathione reductase 0.0139 0.0076 0.0074
Loa Loa (eye worm) ABC transporter 0.0017 0.0001 0.0001
Onchocerca volvulus 0.0018 0.0001 0.0032
Echinococcus granulosus cathepsin l1 0.0018 0.0002 0.0002
Plasmodium vivax flap endonuclease 1, putative 0.0028 0.0008 0.0006
Trypanosoma brucei Vps23 core domain containing protein, putative 0.0023 0.0004 0.0005
Onchocerca volvulus Chorion peroxidase homolog 0.0063 0.0029 0.0646
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.002 0.0003 0.0033
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0164 0.0091 0.0091
Plasmodium falciparum flap endonuclease 1 0.0028 0.0008 0.0006
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0019 0.0002 0.0032
Trypanosoma cruzi metacaspase 5, putative 0.0092 0.0047 0.0063
Loa Loa (eye worm) hypothetical protein 0.0021 0.0003 0.0003
Echinococcus granulosus delta-like protein 1 0.0021 0.0003 0.0003
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0317 0.0185 0.5308
Schistosoma mansoni biogenic amine (5HT) receptor 0.0018 0.0001 0.0001
Mycobacterium ulcerans DNA polymerase IV 0.0102 0.0053 0.1479
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0352 0.0207 0.5935
Trichomonas vaginalis inositol monophosphatase, putative 0.0118 0.0063 0.1691
Loa Loa (eye worm) phosphatidylinositol 3 0.0049 0.0021 0.0021
Onchocerca volvulus Protein cycle homolog 0.0019 0.0002 0.0041
Onchocerca volvulus 0.0063 0.0029 0.0646
Loa Loa (eye worm) hypothetical protein 0.0029 0.0008 0.0008
Trypanosoma cruzi DNA polymerase kappa, putative 0.0102 0.0053 0.0071
Echinococcus multilocularis DNA topoisomerase 1 1.6259 1 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.001 0.0257
Loa Loa (eye worm) oxidoreductase 0.002 0.0003 0.0003
Loa Loa (eye worm) jmjC domain-containing protein 0.0043 0.0017 0.0017
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0017 0.0001 0.0011
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0022 0.0004 0.0004
Mycobacterium leprae Probable DNA topoisomerase I TopA (omega-protein) (relaxing enzyme) (untwisting enzyme) (swivelase) (type I DNA topoisomerase) ( 0.0262 0.0152 0.4328
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0008 0.0007
Trypanosoma brucei hypothetical protein, conserved 0.0226 0.013 0.0174
Onchocerca volvulus 0.0021 0.0003 0.0064
Echinococcus granulosus tumor protein p63 0.037 0.0218 0.0218
Schistosoma mansoni dep domain containing protein 0.0018 0.0001 0.0001
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0001 0.0001
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0048 0.002 0.0517
Plasmodium vivax steroid dehydrogenase, putative 0.002 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.0027 0.0007 0.0007
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0048 0.002 0.002
Plasmodium vivax DNA topoisomerase II, putative 0.006 0.0027 0.0025
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0189 0.0106 0.0143
Echinococcus multilocularis jun protein 0.0086 0.0043 0.0043
Echinococcus multilocularis SAM and MBT domain containing protein 0.0049 0.002 0.002
Trypanosoma brucei glycosyl hydrolase-like protein 0.0018 0.0002 0.0002
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.006 0.0027 0.075
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0164 0.0091 0.0091
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0018 0.0001 0.0001
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0192 0.0109 0.0145
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0001 0.0001
Entamoeba histolytica hypothetical protein 0.03 0.0175 0.4701
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0018 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0028 0.0008 0.001
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0014 0.0018
Trichomonas vaginalis DNA polymerase eta, putative 0.0102 0.0053 0.1425
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.003 0.0009 0.0007
Leishmania major short chain dehydrogenase/reductase, putative 0.002 0.0003 0.0003
Mycobacterium tuberculosis Probable oxidoreductase 0.002 0.0003 0.0056
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0001 0.0001
Brugia malayi Glycosyl hydrolases family 31 protein 0.005 0.0021 0.0021
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0018 0.0002 0.0002
Trypanosoma cruzi short-chain dehydrogenase, putative 0.002 0.0003 0.0003
Trichomonas vaginalis hypothetical protein 0.0035 0.0012 0.03
Trypanosoma cruzi Vps23 core domain containing protein, putative 0.0023 0.0004 0.0005
Plasmodium falciparum ataxin-2 like protein, putative 0.0133 0.0072 0.0071
Onchocerca volvulus 0.0105 0.0055 0.1215
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0013 0.0334
Loa Loa (eye worm) ctsf protein 0.0018 0.0002 0.0002
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.0008 0.0008
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0003 0.0024
Onchocerca volvulus 0.0018 0.0001 0.0032
Trypanosoma cruzi metacaspase, putative 0.0092 0.0047 0.0063
Echinococcus multilocularis snurportin 1 0.0327 0.0192 0.0192
Onchocerca volvulus 0.0027 0.0007 0.0151
Loa Loa (eye worm) hypothetical protein 0.0026 0.0007 0.0007
Brugia malayi N-terminal motif family protein 0.0368 0.0217 0.0217
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Trichomonas vaginalis CAMK family protein kinase 0.0197 0.0112 0.3007
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.002 0.0003 0.0033
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0087 0.0044 0.1166
Echinococcus granulosus carbonyl reductase 1 0.002 0.0003 0.0003
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0003 0.0024
Brugia malayi jmjC domain containing protein 0.0043 0.0017 0.0017
Echinococcus granulosus carbonyl reductase 1 0.002 0.0003 0.0003
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.002 0.0003 0.0003
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0048 0.002 0.0026
Schistosoma mansoni Smad4 0.0019 0.0002 0.0002
Echinococcus multilocularis mothers against decapentaplegic 5 0.0042 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0063 0.0029 0.0029
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0028 0.0008 0.0006
Leishmania major dehydrogenase-like protein 0.002 0.0003 0.0003
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0077 0.0038 0.0038
Echinococcus granulosus hypothetical protein 0.002 0.0003 0.0003
Schistosoma mansoni steroid dehydrogenase 0.002 0.0003 0.0003
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0042 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0005 0.0005
Brugia malayi larval opioid receptor 0.0018 0.0001 0.0001
Onchocerca volvulus 0.002 0.0003 0.0062
Echinococcus multilocularis cpg binding protein 0.0063 0.0029 0.0029
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.002 0.0003 0.0056
Mycobacterium tuberculosis Probable short-chain dehydrogenase/reductase 0.002 0.0003 0.0056
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0002 0.0002
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0003 0.0024
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Brugia malayi MH1 domain containing protein 0.0042 0.0016 0.0016
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0019 0.0002 0.0002
Toxoplasma gondii NADPH-glutathione reductase 0.0048 0.002 0.0018
Plasmodium vivax topoisomerase I, putative 1.6259 1 1
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0087 0.0044 0.1166
Brugia malayi putative neuropeptide receptor 0.0018 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0051 0.0022 0.0022
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0001 0.0001
Schistosoma mansoni myelin transcription factor 1 myt1 0.0055 0.0024 0.0024
Echinococcus multilocularis protein dispatched 1 0.0049 0.0021 0.0021
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.002 0.0003 0.0056
Onchocerca volvulus Huntingtin homolog 0.0388 0.0229 0.5038
Brugia malayi Nuclear hormone receptor-like 1 0.0164 0.0091 0.0091
Trypanosoma brucei DNA damage repair protein, putative 0.0023 0.0005 0.0005
Loa Loa (eye worm) cytochrome P450 0.0019 0.0002 0.0002
Chlamydia trachomatis DNA topoisomerase I 0.0307 0.0179 1
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0003 0.0003
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0081 0.004 0.004
Giardia lamblia Hypothetical protein 0.002 0.0003 0.0019
Loa Loa (eye worm) hypothetical protein 0.002 0.0003 0.0003
Trypanosoma brucei oxidoreductase-like protein 0.002 0.0003 0.0003
Entamoeba histolytica DNA topoisomerase III, putative 0.0137 0.0074 0.1974
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0164 0.0091 0.0091
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0189 0.0106 0.3018
Onchocerca volvulus 0.002 0.0003 0.0062
Schistosoma mansoni alpha-glucosidase 0.0131 0.0071 0.0071
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0002 0.003
Toxoplasma gondii melibiase subfamily protein 0.0217 0.0124 0.0122
Trypanosoma cruzi polo-like protein kinase, putative 0.0197 0.0112 0.015
Loa Loa (eye worm) hypothetical protein 0.0064 0.003 0.003
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0018 0.0001 0.0001
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.002 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0178 0.01 0.01
Loa Loa (eye worm) animal heme peroxidase 0.0063 0.0029 0.0029
Trichomonas vaginalis ran, putative 0.0023 0.0004 0.0101
Brugia malayi Uncoordinated protein 44 0.0016 0.0000000022072 0.0000000022072
Trypanosoma cruzi DNA polymerase kappa, putative 0.0102 0.0053 0.0071
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.006 0.0027 0.0025
Loa Loa (eye worm) hypothetical protein 0.1041 0.0631 0.0631
Onchocerca volvulus 0.0018 0.0002 0.0035
Plasmodium vivax histone acetyltransferase GCN5, putative 0.018 0.0101 0.01
Schistosoma mansoni steroid dehydrogenase 0.002 0.0003 0.0003
Schistosoma mansoni tsg101-related 0.0059 0.0027 0.0027
Echinococcus multilocularis regulator of G protein signaling 3 0.0021 0.0003 0.0003
Trypanosoma cruzi trypanothione reductase, putative 0.0048 0.002 0.0026
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0003 0.0003
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.018 0.0101 0.01
Loa Loa (eye worm) melatonin receptor type 1A 0.0018 0.0001 0.0001
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0164 0.0091 0.0091
Schistosoma mansoni prokaryotic DNA topoisomerase 0.0137 0.0074 0.0074
Echinococcus multilocularis mothers against decapentaplegic 2 0.0019 0.0002 0.0002
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0618 0.0371 1
Loa Loa (eye worm) neuropeptide F receptor 0.0018 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0028 0.0007 0.0007
Echinococcus multilocularis importin subunit beta 1 0.0031 0.0009 0.0009
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.005 0.0021 0.0549
Echinococcus granulosus kelch ECH associated protein 1 like 0.0096 0.005 0.005
Brugia malayi hypothetical protein 0.0019 0.0002 0.0002
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0283 0.0165 0.0165
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0043 0.0017 0.0022
Leishmania major DNA damage repair protein, putative 0.0023 0.0005 0.0005
Trypanosoma brucei MATE efflux family protein, putative 0.007 0.0033 0.0044
Onchocerca volvulus Neurogenic locus notch homolog 0.0021 0.0003 0.0066
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0164 0.0091 0.0091
Echinococcus granulosus caspase 3 0.0152 0.0084 0.0084
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0003 0.0003
Echinococcus granulosus biogenic amine 5HT receptor 0.0018 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0163 0.0091 0.0091
Loa Loa (eye worm) hypothetical protein 0.0028 0.0007 0.0007
Trichomonas vaginalis estradiol 17 beta-dehydrogenase, putative 0.002 0.0003 0.0064
Trypanosoma brucei DNA topoisomerase ii 0.006 0.0027 0.0036
Echinococcus multilocularis musashi 0.0057 0.0025 0.0025
Trypanosoma cruzi cysteine peptidase, putative 0.0018 0.0002 0.0002
Trypanosoma brucei DNA topoisomerase IB, large subunit 1.2096 0.7437 1
Brugia malayi Retinol dehydrogenase 12 0.002 0.0003 0.0003
Onchocerca volvulus 0.0077 0.0038 0.0834
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0008 0.021
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0003 0.0001
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0003 0.0003
Echinococcus multilocularis cathepsin L cysteine protease 0.0018 0.0002 0.0002
Schistosoma mansoni jumonji domain containing protein 0.0201 0.0114 0.0114
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0014 0.0377
Brugia malayi aryl hydrocarbon receptor AHR-1 0.0019 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Trichomonas vaginalis glucosylceramidase, putative 0.0186 0.0105 0.2813
Loa Loa (eye worm) hypothetical protein 0.0633 0.038 0.038
Trichomonas vaginalis DNA topoisomerase II, putative 0.006 0.0027 0.0715
Echinococcus multilocularis neuropeptide s receptor 0.0018 0.0001 0.0001
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0021 0.0003 0.0003
Loa Loa (eye worm) globin family protein 0.0027 0.0007 0.0007
Brugia malayi jmjC domain containing protein 0.0043 0.0017 0.0017
Trypanosoma cruzi major cysteine proteinase, putative 0.0055 0.0024 0.0032
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0164 0.0091 0.0091
Loa Loa (eye worm) hypothetical protein 0.0633 0.038 0.038
Toxoplasma gondii ATP-binding cassette G family transporter ABCG84 0.0021 0.0003 0.0002
Trichomonas vaginalis short-chain dehydrogenase, putative 0.002 0.0003 0.0064
Brugia malayi hypothetical protein 0.002 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0021 0.0544
Schistosoma mansoni tsg101-related 0.0048 0.002 0.002
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0048 0.002 0.0026
Echinococcus multilocularis transcription factor Dp 1 0.004 0.0015 0.0015
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0317 0.0185 0.5293
Echinococcus multilocularis 0.0019 0.0002 0.0002
Echinococcus granulosus JmjC domain containing protein 4 0.0043 0.0017 0.0017
Trypanosoma brucei DNA polymerase kappa, putative 0.0102 0.0053 0.0071
Echinococcus multilocularis steroid dehydrogenase 0.002 0.0003 0.0003
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.005 0.0021 0.0019
Loa Loa (eye worm) hypothetical protein 0.0021 0.0003 0.0003
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0145 0.0079 0.0079
Echinococcus granulosus notch 0.0021 0.0003 0.0003
Brugia malayi Smad1 0.0042 0.0016 0.0016
Trypanosoma brucei short-chain dehydrogenase, putative 0.002 0.0003 0.0003
Loa Loa (eye worm) CXXC zinc finger family protein 0.006 0.0027 0.0027
Echinococcus multilocularis histone acetyltransferase MYST2 0.0055 0.0024 0.0024
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.002 0.0003 0.0003
Trypanosoma cruzi DNA polymerase kappa, putative 0.0102 0.0053 0.0071
Schistosoma mansoni hypothetical protein 0.1244 0.0756 0.0756
Trichomonas vaginalis CAMK family protein kinase 0.0197 0.0112 0.3007
Mycobacterium tuberculosis Decaprenylphosphoryl-D-2-keto erythro pentose reductase 0.002 0.0003 0.0056
Echinococcus multilocularis flap endonuclease 1 0.0028 0.0008 0.0008
Leishmania major cathepsin L-like protease 0.007 0.0033 0.0044
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0192 0.0109 0.0109
Brugia malayi Nuclear hormone receptor-like 1 0.0087 0.0044 0.0044
Echinococcus multilocularis neutral alpha glucosidase AB 0.005 0.0021 0.0021
Leishmania major cathepsin L-like protease 0.007 0.0033 0.0044
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0002 0.003
Schistosoma mansoni steroid hormone receptor ad4bp 0.0164 0.0091 0.0091
Echinococcus granulosus ferritin 0.0036 0.0012 0.0012
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0618 0.0371 1
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0019 0.0002 0.0002
Brugia malayi Tachykinin-like peptides receptor 99D 0.0018 0.0001 0.0001
Echinococcus granulosus dro:myosuppressin receptor 0.0018 0.0001 0.0001
Brugia malayi Muscleblind-like protein 0.0633 0.038 0.038
Echinococcus granulosus DNA topoisomerase 1 1.6259 1 1
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0087 0.0044 0.1166
Echinococcus granulosus axis inhibition protein axin 0.0021 0.0003 0.0003
Onchocerca volvulus 0.0057 0.0025 0.0559
Trypanosoma cruzi ATP-binding cassette protein, putative 0.0021 0.0003 0.0003
Echinococcus granulosus tachykinin peptides receptor 99D 0.0018 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0006 0.0139
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Loa Loa (eye worm) oxidoreductase 0.002 0.0003 0.0003
Onchocerca volvulus Dual oxidase homolog 0.0063 0.0029 0.0646
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0002 0.0003
Echinococcus granulosus intermediate filament protein 0.0057 0.0025 0.0025
Onchocerca volvulus 0.0018 0.0002 0.0035
Entamoeba histolytica hypothetical protein 0.0025 0.0006 0.0109
Echinococcus granulosus lysine specific demethylase 6a 0.0043 0.0017 0.0017
Schistosoma mansoni short chain dehydrogenase 0.002 0.0003 0.0003
Schistosoma mansoni serine/threonine protein kinase 0.0184 0.0104 0.0104
Echinococcus multilocularis nuclear receptor nhr 48 0.0077 0.0038 0.0038
Brugia malayi hypothetical protein 0.0077 0.0038 0.0038
Brugia malayi hypothetical protein 0.0027 0.0007 0.0007
Echinococcus granulosus neuropeptide Y receptor 0.0018 0.0001 0.0001
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0023 0.0004 0.0004
Echinococcus granulosus sex peptide receptor 0.0018 0.0001 0.0001
Loa Loa (eye worm) animal heme peroxidase 0.0063 0.0029 0.0029
Schistosoma mansoni smad1 5 8 and 0.0042 0.0016 0.0016
Brugia malayi EGF-like domain containing protein 0.0021 0.0003 0.0003
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0065 0.003 0.003
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0164 0.0091 0.0091
Onchocerca volvulus 0.0027 0.0007 0.0151
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Echinococcus granulosus histone acetyltransferase KAT2B 0.018 0.0101 0.0101
Chlamydia trachomatis DNA gyrase subunit B 0.006 0.0027 0.0441
Schistosoma mansoni nuclear hormone receptor 0.0077 0.0038 0.0038
Echinococcus granulosus axis inhibition protein axin 0.0021 0.0003 0.0003
Trypanosoma cruzi ABC transporter, putative 0.0021 0.0003 0.0003
Schistosoma mansoni Smad4 0.0042 0.0016 0.0016
Onchocerca volvulus Cathepsin F homolog 0.0018 0.0002 0.0035
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.002 0.0003 0.0056
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0001 0.0001
Echinococcus granulosus carbonyl reductase 1 0.002 0.0003 0.0003
Brugia malayi mbt repeat family protein 0.0049 0.002 0.002
Trypanosoma brucei ATP-binding cassette protein, putative 0.0021 0.0003 0.0003
Mycobacterium ulcerans bacterioferritin BfrB 0.0036 0.0012 0.0299
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0003 0.0003
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0618 0.0371 1
Loa Loa (eye worm) hypothetical protein 0.0053 0.0023 0.0023
Schistosoma mansoni globin X 0.0027 0.0007 0.0007
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0048 0.002 0.1004
Onchocerca volvulus 0.0049 0.002 0.0447
Echinococcus granulosus neurogenic locus protein delta 0.0021 0.0003 0.0003
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0118 0.0063 0.0084
Leishmania major metacaspase, putative 0.0092 0.0047 0.0063
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0016 0.0000082465 0.0000082465
Trichomonas vaginalis alpha-glucosidase, putative 0.005 0.0021 0.0549
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0092 0.0047 0.1258
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0001 0.0001
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0164 0.0091 0.0091
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0048 0.002 0.0026
Schistosoma mansoni ABC transporter 0.0017 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0021 0.0003 0.0003
Loa Loa (eye worm) transcription factor SMAD2 0.0622 0.0373 0.0373
Echinococcus granulosus g protein coupled receptor 0.0018 0.0001 0.0001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0001 0.0001
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0092 0.0047 0.1258
Loa Loa (eye worm) hypothetical protein 0.0027 0.0007 0.0007
Trichomonas vaginalis alpha-glucosidase, putative 0.005 0.0021 0.0549
Schistosoma mansoni importin beta-1 0.0031 0.0009 0.0009
Loa Loa (eye worm) jmjC domain-containing protein 0.0043 0.0017 0.0017
Onchocerca volvulus 0.0021 0.0003 0.0064
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0018 0.0002 0.0002
Brugia malayi TAR-binding protein 0.0069 0.0033 0.0033
Schistosoma mansoni axis inhibition protein axin 0.0021 0.0003 0.0003
Schistosoma mansoni biogenic amine receptor 0.0018 0.0001 0.0001
Brugia malayi Glycosyl hydrolases family 31 protein 0.0018 0.0002 0.0002
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0019 0.0002 0.0032
Schistosoma mansoni DNA topoisomerase type I 1.6259 1 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0003 0.0003
Brugia malayi Calcium binding EGF domain containing protein 0.0021 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Echinococcus granulosus Ankyrin 0.0016 0.0000082487 0.0000082487
Trypanosoma brucei ABC transporter, putative 0.0021 0.0003 0.0003
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0002 0.003
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0106 0.0055 0.1571
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0049 0.0021 0.0515
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0092 0.0047 0.0046
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0011 0.0275
Trypanosoma brucei DNA polymerase kappa, putative 0.0102 0.0053 0.0071
Echinococcus multilocularis lamin dm0 0.0057 0.0025 0.0025
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0002 0.003
Trypanosoma brucei DNA topoisomerase IA, putative 0.0262 0.0152 0.0204
Trypanosoma brucei membrane transporter protein, putative 0.007 0.0033 0.0044
Plasmodium falciparum ataxin-2 like protein, putative 0.0133 0.0072 0.0071
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0302 0.0176 0.5046
Schistosoma mansoni hypothetical protein 0.0327 0.0192 0.0192
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0164 0.0091 0.0091
Echinococcus granulosus cpg binding protein 0.0063 0.0029 0.0029
Echinococcus granulosus mothers against decapentaplegic 6 0.0019 0.0002 0.0002
Toxoplasma gondii DNA topoisomerase family protein 0.0262 0.0152 0.015
Onchocerca volvulus 0.0063 0.0029 0.0646
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.005 0.0021 0.0021
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0049 0.0021 0.0027
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0049 0.0021 0.0021
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0002 0.0002
Echinococcus multilocularis axis inhibition protein axin 0.0021 0.0003 0.0003
Echinococcus granulosus Nuclear hormone receptor HR96 0.0077 0.0038 0.0038
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0038 0.0014 0.0014
Brugia malayi photoreceptor-specific nuclear receptor 0.1153 0.07 0.07
Trypanosoma brucei DNA polymerase kappa, putative 0.0051 0.0022 0.0028
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0003 0.0075
Brugia malayi Death domain containing protein 0.0016 0.0000000022072 0.0000000022072
Loa Loa (eye worm) TOPoisomerase family member 0.006 0.0027 0.0027
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0197 0.0112 0.0112
Onchocerca volvulus 0.002 0.0003 0.0062
Trypanosoma cruzi hypothetical protein, conserved 0.0226 0.013 0.0174
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0217 0.0124 0.0124
Onchocerca volvulus 0.0018 0.0001 0.0032
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0048 0.002 0.0018
Loa Loa (eye worm) RGS-3 protein 0.0021 0.0003 0.0003
Schistosoma mansoni short chain dehydrogenase 0.002 0.0003 0.0003
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0069 0.0033 0.0033
Echinococcus granulosus neuropeptides capa receptor 0.0018 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0388 0.0229 0.0229
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0162 0.009 0.009
Echinococcus granulosus tm gpcr rhodopsin 0.0018 0.0001 0.0001
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0164 0.0091 0.0091
Leishmania major hypothetical protein, conserved 0.0023 0.0004 0.0005
Schistosoma mansoni hypothetical protein 0.03 0.0175 0.0175
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0021 0.0003 0.0003
Echinococcus multilocularis citrate lyase subunit beta protein 0.0026 0.0006 0.0006
Brugia malayi EGF-like domain containing protein 0.0021 0.0003 0.0003
Plasmodium falciparum histone acetyltransferase GCN5 0.0165 0.0092 0.009
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0038 0.0014 0.0014
Onchocerca volvulus 0.0224 0.0128 0.2816
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0087 0.0044 0.0058
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0092 0.0047 0.0047
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.002 0.0003 0.0056
Echinococcus granulosus protein jagged 2 0.0021 0.0003 0.0003
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0033 0.0044
Brugia malayi Animal haem peroxidase family protein 0.0063 0.0029 0.0029
Entamoeba histolytica ABC transporter, putative 0.0021 0.0003 0.0037
Entamoeba histolytica hypothetical protein, conserved 0.002 0.0003 0.0033
Mycobacterium tuberculosis Probable short chain alcohol dehydrogenase/reductase 0.002 0.0003 0.0056
Loa Loa (eye worm) hypothetical protein 0.0063 0.0029 0.0029
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0018 0.0001 0.0001
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0004 0.0004
Mycobacterium ulcerans dehydrogenase/reductase 0.002 0.0003 0.0024
Trichomonas vaginalis glucosylceramidase, putative 0.0283 0.0165 0.4432
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Brugia malayi isocitrate dehydrogenase 0.0098 0.0051 0.0051
Entamoeba histolytica 3-ketodihydrosphingosine reductase protein, putative 0.002 0.0003 0.0033
Loa Loa (eye worm) hypothetical protein 0.002 0.0003 0.0003
Schistosoma mansoni cathepsin F (C01 family) 0.0018 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0174 0.0098 0.0098
Loa Loa (eye worm) hypothetical protein 0.0087 0.0044 0.0044
Trypanosoma cruzi cysteine peptidase, putative 0.007 0.0033 0.0044
Brugia malayi dehydrogenases, short chain protein 2 0.002 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0077 0.0038 0.0038
Leishmania major ATP-binding cassette protein subfamily G, member 6, putative 0.0021 0.0003 0.0003
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0118 0.0063 0.1691
Brugia malayi conserved hypotetical protein 0.0077 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0101 0.0052 0.0052
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0038 0.0014 0.0014
Trichomonas vaginalis CAMK family protein kinase 0.0197 0.0112 0.3007
Echinococcus granulosus mothers against decapentaplegic 2 0.0019 0.0002 0.0002
Echinococcus granulosus mixed lineage leukemia protein mll 0.0017 0.0001 0.0001
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.0021 0.0021
Echinococcus granulosus ATP binding cassette sub family G 0.0021 0.0003 0.0003
Onchocerca volvulus 0.002 0.0003 0.0062
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0088 0.0044 0.0059
Plasmodium vivax importin-beta 2, putative 0.0031 0.0009 0.0008
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0077 0.0038 0.0038
Leishmania major short chain dehydrogenase/reductase, putative 0.002 0.0003 0.0003
Loa Loa (eye worm) TAR-binding protein 0.0069 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Onchocerca volvulus 0.0018 0.0001 0.0032
Trypanosoma brucei DNA polymerase kappa, putative 0.0102 0.0053 0.0071
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0018 0.0001 0.0001
Toxoplasma gondii DNA topoisomerase I, putative 1.6259 1 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0018 0.0002 0.0032
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0019 0.0002 0.0032
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0197 0.0112 0.0112
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0008 0.0008
Echinococcus granulosus lysine specific demethylase 5A 0.0164 0.0091 0.0091
Schistosoma mansoni steroid dehydrogenase 0.002 0.0003 0.0003
Brugia malayi MH1 domain containing protein 0.0023 0.0005 0.0005
Schistosoma mansoni hypothetical protein 0.0021 0.0003 0.0003
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0069 0.0033 0.0033
Plasmodium falciparum JmjC domain-containing protein, putative 0.0043 0.0017 0.0015
Trichomonas vaginalis glucosylceramidase, putative 0.0186 0.0105 0.2813
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0022 0.0004 0.0004
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.002 0.0003 0.0024
Echinococcus multilocularis zinc finger protein 0.0018 0.0002 0.0002
Brugia malayi Cathepsin L-like precursor 0.0018 0.0002 0.0002
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0077 0.0038 0.0038
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0002 0.003
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0021 0.0003 0.0003
Mycobacterium tuberculosis Possible oxidoreductase 0.002 0.0003 0.0056
Trypanosoma brucei membrane transporter protein, putative 0.007 0.0033 0.0044
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.002 0.0003 0.0024
Schistosoma mansoni coup transcription factor 0.0164 0.0091 0.0091
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0038 0.0014 0.0018
Schistosoma mansoni RAR-like nuclear receptor 0.0164 0.0091 0.0091
Onchocerca volvulus DNA topoisomerase 2 homolog 0.006 0.0027 0.0592
Leishmania major hypothetical protein, conserved 0.002 0.0003 0.0003
Loa Loa (eye worm) animal heme peroxidase 0.0063 0.0029 0.0029
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0018 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0002
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0118 0.0063 0.1665
Loa Loa (eye worm) blistered cuticle protein 3 0.0063 0.0029 0.0029
Trypanosoma brucei short-chain dehydrogenase, putative 0.002 0.0003 0.0003
Leishmania major cathepsin L-like protease 0.0018 0.0002 0.0002
Schistosoma mansoni ferritin light chain 0.0036 0.0012 0.0012
Trypanosoma brucei DNA polymerase kappa, putative 0.0102 0.0053 0.0071
Schistosoma mansoni hypothetical protein 0.0021 0.0003 0.0003
Echinococcus granulosus G protein coupled receptor 139 0.0018 0.0001 0.0001
Schistosoma mansoni retinoic acid receptor RXR 0.0164 0.0091 0.0091
Trichomonas vaginalis conserved hypothetical protein 0.0092 0.0047 0.1258
Echinococcus granulosus retinol dehydrogenase 11 0.002 0.0003 0.0003
Entamoeba histolytica hypothetical protein 0.002 0.0003 0.0033
Onchocerca volvulus 0.002 0.0003 0.0062
Plasmodium falciparum ABC transporter G family member 2 0.0021 0.0003 0.0001
Leishmania major DNA topoisomerase III, putative 0.0314 0.0184 0.0246
Brugia malayi hypothetical protein 0.0086 0.0043 0.0043
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0021 0.0003 0.0064
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0189 0.0106 0.0106
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0001 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.0102 0.0053 0.0071
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0164 0.0091 0.0091
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0003 0.0003
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0021 0.0003 0.0003
Echinococcus multilocularis multidrug and toxin extrusion protein 2 0.007 0.0033 0.0033
Schistosoma mansoni ap endonuclease 0.0019 0.0002 0.0002
Brugia malayi nuclear receptor NHR-88 0.0164 0.0091 0.0091
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0003 0.0024
Brugia malayi Cytochrome P450 family protein 0.004 0.0015 0.0015
Schistosoma mansoni ferritin 0.0036 0.0012 0.0012
Echinococcus multilocularis neurogenic locus protein delta 0.0021 0.0003 0.0003
Echinococcus granulosus retinol dehydrogenase 11 0.002 0.0003 0.0003
Plasmodium falciparum thioredoxin reductase 0.0139 0.0076 0.0074
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0065 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0164 0.0091 0.0091
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0003 0.0003
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0057 0.0025 0.0025
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0174 0.0098 0.2604
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0118 0.0063 0.0084
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0077 0.0038 0.0038
Plasmodium vivax metacaspase 1, putative 0.0092 0.0047 0.0045
Trypanosoma brucei DNA polymerase kappa, putative 0.0102 0.0053 0.0071
Trichomonas vaginalis alpha-glucosidase, putative 0.005 0.0021 0.0549
Loa Loa (eye worm) hypothetical protein 0.0021 0.0003 0.0003
Echinococcus granulosus Smad4 0.0042 0.0016 0.0016
Echinococcus granulosus survival motor neuron protein 1 0.1483 0.0903 0.0903
Schistosoma mansoni flap endonuclease-1 0.0026 0.0006 0.0006
Entamoeba histolytica hypothetical protein 0.0021 0.0003 0.0044
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0102 0.0053 0.0053
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0018 0.0001 0.0001
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0043 0.0017 0.0022
Onchocerca volvulus 0.0068 0.0032 0.0704
Leishmania major DNA topoisomerase 1A 0.0262 0.0152 0.0204
Mycobacterium ulcerans ketoacyl reductase 0.002 0.0003 0.0024
Brugia malayi intermediate filament protein 0.0057 0.0025 0.0025
Echinococcus multilocularis tumor susceptibility gene 101 protein 0.0071 0.0034 0.0034
Echinococcus granulosus apoptotic protease activating factor 1 0.0086 0.0043 0.0043
Echinococcus multilocularis lysine specific demethylase 5A 0.0161 0.0089 0.0089
Onchocerca volvulus 0.0508 0.0303 0.6659
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0092 0.0047 0.1258
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.002 0.0003 0.0003
Echinococcus multilocularis Ankyrin 0.0016 0.0000082487 0.0000082487
Trypanosoma brucei DNA polymerase kappa, putative 0.0051 0.0022 0.0028
Brugia malayi hypothetical protein 0.03 0.0175 0.0175
Loa Loa (eye worm) hypothetical protein 0.0063 0.0029 0.0029
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0008 0.0007
Trypanosoma cruzi metacaspase, putative 0.0092 0.0047 0.0063
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0017 0.0001 0.0001
Mycobacterium tuberculosis Possible oxidoreductase 0.002 0.0003 0.0056
Trichomonas vaginalis glucosylceramidase, putative 0.0186 0.0105 0.2813
Echinococcus granulosus neuropeptide receptor A26 0.0018 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Brugia malayi Globin family protein 0.0027 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0063 0.0029 0.0029
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0014 0.0377
Leishmania major protein kinase, putative 0.0096 0.0049 0.0066
Echinococcus granulosus protein jagged 1 0.0021 0.0003 0.0003
Leishmania major hypothetical protein, conserved 0.002 0.0003 0.0003
Echinococcus multilocularis smad 0.0042 0.0016 0.0016
Trypanosoma cruzi DNA topoisomerase type IB small subunit, putative 0.5675 0.3484 0.4684
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0077 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0077 0.0038 0.0038
Loa Loa (eye worm) PXA domain-containing protein 0.0021 0.0003 0.0003
Mycobacterium ulcerans short-chain membrane-associated dehydrogenase 0.002 0.0003 0.0024
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Brugia malayi jmjC domain containing protein 0.0164 0.0091 0.0091
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0002 0.0045
Schistosoma mansoni amine GPCR 0.0018 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0077 0.0038 0.0038
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0002 0.003
Echinococcus multilocularis steroid dehydrogenase 0.002 0.0003 0.0003
Echinococcus granulosus serotonin receptor 0.0018 0.0001 0.0001
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0028 0.0008 0.001
Echinococcus multilocularis neurogenic locus notch protein 4 0.0021 0.0003 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0003 0.0075
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0192 0.0109 0.3102
Plasmodium falciparum steroid dehydrogenase, putative 0.002 0.0003 0.0001
Leishmania major oxidoreductase-like protein 0.002 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0056 0.0025 0.0025
Schistosoma mansoni alpha glucosidase 0.005 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0087 0.0044 0.0044
Brugia malayi Calcium binding EGF domain containing protein 0.0021 0.0003 0.0003
Trypanosoma brucei DNA polymerase eta, putative 0.0127 0.0069 0.0092
Trichomonas vaginalis short-chain dehydrogenase, putative 0.002 0.0003 0.0064
Mycobacterium ulcerans hypothetical protein 0.0026 0.0006 0.0125
Schistosoma mansoni aldehyde dehydrogenase 0.0192 0.0109 0.0109
Entamoeba histolytica oxidoreductase, short chain dehydrogenase/reductase family 0.002 0.0003 0.0033
Schistosoma mansoni myosin xvIII 0.0018 0.0001 0.0001
Trypanosoma brucei polo-like protein kinase 0.0197 0.0112 0.015
Trichomonas vaginalis conserved hypothetical protein 0.0087 0.0044 0.1166
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0088 0.0044 0.0059
Schistosoma mansoni hypothetical protein 0.0017 0.0001 0.0001
Giardia lamblia ABC transporter 0.002 0.0003 0.0019
Trypanosoma cruzi hypothetical protein, conserved 0.007 0.0033 0.0044
Echinococcus multilocularis ferritin 0.0036 0.0012 0.0012
Onchocerca volvulus Alhambra homolog 0.0029 0.0008 0.0185
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0018 0.0001 0.0001
Trypanosoma brucei DNA topoisomerase III, putative 0.0137 0.0074 0.0099
Schistosoma mansoni hypothetical protein 0.0042 0.0016 0.0016
Echinococcus granulosus tm gpcr rhodopsin 0.0018 0.0001 0.0001
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0164 0.0091 0.0091
Brugia malayi Regulator of G protein signaling domain containing protein 0.0021 0.0003 0.0003
Echinococcus multilocularis neuropeptide receptor 0.0018 0.0001 0.0001
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0081 0.004 0.1138
Entamoeba histolytica short chain dehydrogenase family protein 0.002 0.0003 0.0033
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0164 0.0091 0.0091
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0002 0.0045
Echinococcus multilocularis peroxidasin 0.0064 0.003 0.003
Loa Loa (eye worm) intermediate filament protein 0.0057 0.0025 0.0025
Schistosoma mansoni cell polarity protein 0.0021 0.0003 0.0003
Onchocerca volvulus 0.0018 0.0002 0.0035
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.006 0.0027 0.1401
Echinococcus granulosus muscleblind protein 0.0633 0.038 0.038
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0002 0.003
Echinococcus multilocularis inositol monophosphatase 1 0.0118 0.0063 0.0063
Loa Loa (eye worm) steroid hormone receptor 0.0164 0.0091 0.0091
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0352 0.0207 0.5922
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0184 0.0104 0.0104
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0021 0.0003 0.0028
Trichomonas vaginalis prokaryotic DNA topoisomerase, putative 0.0077 0.0038 0.1009
Echinococcus granulosus neuropeptide FF receptor 2 0.0018 0.0001 0.0001
Echinococcus multilocularis segment polarity protein dishevelled 0.0018 0.0001 0.0001
Schistosoma mansoni short chain dehydrogenase 0.002 0.0003 0.0003
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0003 0.0024
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0002 0.0002
Loa Loa (eye worm) flap endonuclease-1 0.0028 0.0008 0.0008
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0018 0.0001 0.0001
Schistosoma mansoni steroid dehydrogenase 0.002 0.0003 0.0003
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.002 0.0003 0.0033
Toxoplasma gondii LsmAD domain-containing protein 0.0133 0.0072 0.0071
Schistosoma mansoni jumonji/arid domain-containing protein 0.0164 0.0091 0.0091
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0092 0.0047 0.0046
Mycobacterium ulcerans short-chain dehydrogenase 0.002 0.0003 0.0024
Onchocerca volvulus Slit protein homolog 0.0021 0.0003 0.0068
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0018 0.0001 0.0001
Schistosoma mansoni biogenic amine receptor 0.0018 0.0001 0.0001
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.002 0.0003 0.0024
Loa Loa (eye worm) hypothetical protein 0.002 0.0003 0.0003
Brugia malayi cytochrome P450 0.0019 0.0002 0.0002
Trichomonas vaginalis short-chain dehydrogenase, putative 0.002 0.0003 0.0064
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0244 0.014 0.014
Schistosoma mansoni ferritin 0.0036 0.0012 0.0012
Schistosoma mansoni aryl hydrocarbon receptor nuclear translocator homolog (darnt) 0.0019 0.0002 0.0002
Loa Loa (eye worm) DNA topoisomerase I 1.6259 1 1
Onchocerca volvulus Neuropeptide F receptor homolog 0.0018 0.0001 0.0032
Schistosoma mansoni zinc finger protein 0.0018 0.0002 0.0002
Treponema pallidum fructose-bisphosphate aldolase 0.0618 0.0371 1
Brugia malayi ABC transporter family protein 0.0017 0.0001 0.0001
Echinococcus multilocularis neuropeptides capa receptor 0.0018 0.0001 0.0001
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0164 0.0091 0.0091
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Echinococcus multilocularis transfer RNA-Lys 0.0224 0.0128 0.0128
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0221 0.0127 0.0127
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0018 0.0001 0.0001
Trypanosoma brucei metacaspase MCA2 0.0092 0.0047 0.0063
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0106 0.0055 0.1544
Schistosoma mansoni retinal dehydrogenase 0.002 0.0003 0.0003
Brugia malayi Nuclear hormone receptor E75 0.0077 0.0038 0.0038
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.03 0.0175 0.0175
Schistosoma mansoni dishevelled 0.0018 0.0001 0.0001
Mycobacterium tuberculosis Possible fatty acyl-CoA reductase 0.002 0.0003 0.0056
Trichomonas vaginalis maltase-glucoamylase, putative 0.0018 0.0002 0.0032
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.002 0.0003 0.0024
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0055 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0003 0.0003
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0046 0.0019 0.0019
Trichomonas vaginalis glucosylceramidase, putative 0.0283 0.0165 0.4432
Schistosoma mansoni terminal deoxycytidyl transferase 0.0075 0.0036 0.0036
Brugia malayi Regulator of G protein signaling domain containing protein 0.0021 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Leishmania major DNA polymerase eta, putative 0.0127 0.0069 0.0092
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0031 0.0009 0.0009
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0217 0.0124 0.0124
Echinococcus multilocularis geminin 0.1244 0.0756 0.0756
Echinococcus granulosus kelch ECH associated protein 1 like 0.0096 0.005 0.005
Mycobacterium ulcerans dehydrogenase 0.002 0.0003 0.0024
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0087 0.0044 0.0044
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0075 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0098 0.0051 0.0051
Brugia malayi hypothetical protein 0.0018 0.0001 0.0001
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0019 0.0002 0.0032
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0164 0.0091 0.0091
Plasmodium falciparum topoisomerase I 1.6259 1 1
Onchocerca volvulus Serine\/threonine kinase homolog 0.0197 0.0112 0.2458
Trichomonas vaginalis bromodomain-containing protein, putative 0.018 0.0101 0.2724
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.002 0.0003 0.0003
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0118 0.0063 0.0062
Echinococcus multilocularis apoptotic protease activating factor 1 0.0086 0.0043 0.0043
Echinococcus multilocularis ecdysone induced protein 78C 0.0164 0.0091 0.0091
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0017 0.0443
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0048 0.002 0.0018
Schistosoma mansoni peroxidasin 0.0063 0.0029 0.0029
Echinococcus granulosus g protein coupled receptor 0.0018 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0077 0.0038 0.0038
Brugia malayi hypothetical protein 0.0018 0.0001 0.0001
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0018 0.0001 0.0001
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0018 0.0002 0.0002
Loa Loa (eye worm) DR-78 0.0077 0.0038 0.0038
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0003 0.0024
Onchocerca volvulus 0.0018 0.0001 0.0032
Echinococcus multilocularis neuropeptide receptor 0.0018 0.0001 0.0001
Mycobacterium tuberculosis Conserved protein 0.0026 0.0006 0.0157
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0001 0.0001
Echinococcus multilocularis rho GTPase activating protein 20 0.027 0.0156 0.0156
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0028 0.0008 0.001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0001 0.0001
Trichomonas vaginalis guanylate cyclase, putative 0.0087 0.0044 0.1166
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0003 0.0003
Echinococcus granulosus flap endonuclease 1 0.0028 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0054 0.0024 0.0024
Mycobacterium ulcerans oxidoreductase 0.002 0.0003 0.0024
Echinococcus granulosus regulator of G protein signaling 3 0.0021 0.0003 0.0003
Onchocerca volvulus 0.0018 0.0001 0.0032
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0036 0.0012 0.0577
Onchocerca volvulus Sepiapterin reductase homolog 0.002 0.0003 0.0062
Leishmania major hypothetical protein, conserved 0.0043 0.0017 0.0022
Trichomonas vaginalis flap endonuclease-1, putative 0.0028 0.0008 0.0198
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.002 0.0003 0.0003
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0164 0.0091 0.0091
Schistosoma mansoni hypothetical protein 0.0018 0.0001 0.0001
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0098 0.0051 0.0049
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0027 0.0007 0.0007
Trypanosoma brucei DNA topoisomerase type IB small subunit 0.5675 0.3484 0.4684
Schistosoma mansoni neuropeptide receptor 0.0018 0.0001 0.0001
Echinococcus multilocularis regulator of G protein signaling 7 0.0039 0.0014 0.0014
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0038 0.0014 0.0014
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0001 0.0001
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.002 0.0003 0.0003
Trypanosoma brucei chrX additional, unordered contigs 0.0023 0.0005 0.0005
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0001 0.0001
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.002 0.0003 0.0003
Onchocerca volvulus 0.0018 0.0001 0.0032
Mycobacterium ulcerans short-chain dehydrogenase 0.002 0.0003 0.0024
Schistosoma mansoni short chain dehydrogenase 0.002 0.0003 0.0003
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0164 0.0091 0.0091
Trichomonas vaginalis prokaryotic DNA topoisomerase, putative 0.0262 0.0152 0.4088
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0002 0.003
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0145 0.0079 0.0079
Echinococcus granulosus snurportin 1 0.0327 0.0192 0.0192
Mycobacterium tuberculosis Probable oxidoreductase 0.002 0.0003 0.0056
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0092 0.0047 0.1258
Brugia malayi EGF-like domain containing protein 0.0021 0.0003 0.0003
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.002 0.0003 0.0024
Trypanosoma cruzi oxidoreductase-like protein, putative 0.002 0.0003 0.0003
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0021 0.0003 0.0003
Schistosoma mansoni cpg binding protein 0.0063 0.0029 0.0029
Plasmodium falciparum DNA gyrase subunit B 0.006 0.0027 0.0025
Schistosoma mansoni short chain dehydrogenase 0.002 0.0003 0.0003
Brugia malayi jmjC domain containing protein 0.0043 0.0017 0.0017
Echinococcus multilocularis thioredoxin glutathione reductase 0.0139 0.0076 0.0076
Echinococcus granulosus segment polarity protein dishevelled 0.0018 0.0001 0.0001
Echinococcus granulosus caspase 2 0.0178 0.01 0.01
Echinococcus multilocularis neuropeptide Y receptor 0.0018 0.0001 0.0001
Trichomonas vaginalis glucosylceramidase, putative 0.0186 0.0105 0.2813
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0164 0.0091 0.0091
Loa Loa (eye worm) nuclear factor I 0.0023 0.0005 0.0005
Trypanosoma brucei DNA polymerase IV, putative 0.0102 0.0053 0.0071
Echinococcus multilocularis G protein coupled receptor 139 0.0018 0.0001 0.0001
Brugia malayi hypothetical protein 0.0087 0.0044 0.0044
Echinococcus granulosus kelch ECH associated protein 1 0.0096 0.005 0.005
Giardia lamblia NADH oxidase lateral transfer candidate 0.0048 0.002 0.0482
Trypanosoma brucei DNA polymerase kappa, putative 0.0102 0.0053 0.0071
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.002 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.0063 0.0029 0.0029
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0019 0.0002 0.0032
Toxoplasma gondii DNA topoisomerase 2, putative 0.006 0.0027 0.0025
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0006 0.0139
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0003 0.0024
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.002 0.0003 0.0003
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0019 0.0002 0.0032
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0018 0.0001 0.0001
Echinococcus granulosus 7tm_1 domain containing protein 0.0018 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0021 0.0003 0.0003
Echinococcus granulosus single minded 2 0.0224 0.0128 0.0128
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0003 0.0003
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0164 0.0091 0.0091
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.002 0.0003 0.0024
Loa Loa (eye worm) hypothetical protein 0.0049 0.002 0.002
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0026 0.0006 0.0008
Brugia malayi hypothetical protein 0.0077 0.0038 0.0038
Plasmodium vivax JmjC domain containing protein 0.0043 0.0017 0.0015
Echinococcus granulosus regulator of G protein signaling 7 0.0039 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Giardia lamblia High cysteine protein 0.0021 0.0003 0.0022
Brugia malayi Thioredoxin reductase 0.0139 0.0076 0.0076
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0019 0.0002 0.0002
Echinococcus granulosus carbonyl reductase 1 0.002 0.0003 0.0003
Brugia malayi Protein kinase domain containing protein 0.0017 0.0001 0.0001
Schistosoma mansoni myoglobin 1 0.0027 0.0007 0.0007
Brugia malayi hypothetical protein 0.002 0.0003 0.0003
Schistosoma mansoni notch 0.0021 0.0003 0.0003
Trichomonas vaginalis CAMK family protein kinase 0.0197 0.0112 0.3007
Echinococcus granulosus caspase 0.0244 0.014 0.014
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0004 0.0004
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0092 0.0047 0.1258
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0018 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.0021 0.0021
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0016 0.0000000022072 0.0000000022072
Brugia malayi hypothetical protein 0.0027 0.0007 0.0007
Echinococcus granulosus cathepsin L cysteine proteinase 0.0018 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0164 0.0091 0.0091
Brugia malayi Protein kinase domain containing protein 0.0184 0.0104 0.0104
Brugia malayi hypothetical protein 0.0133 0.0072 0.0072
Plasmodium vivax glutathione reductase, putative 0.0139 0.0076 0.0074
Echinococcus multilocularis neuropeptide FF receptor 2 0.0018 0.0001 0.0001
Trypanosoma cruzi hypothetical protein, conserved 0.005 0.0021 0.0027
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0001 0.0001
Echinococcus multilocularis regulator of G protein signaling 3 0.0021 0.0003 0.0003
Mycobacterium tuberculosis Probable oxidoreductase 0.002 0.0003 0.0056
Schistosoma mansoni cytochrome P450 0.0019 0.0002 0.0002
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0164 0.0091 0.0091
Mycobacterium tuberculosis Probable reductase 0.0317 0.0185 0.5308
Schistosoma mansoni smad1 5 8 and 0.0042 0.0016 0.0016
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0069 0.0033 0.0033
Echinococcus multilocularis lysosomal alpha glucosidase 0.0162 0.009 0.009
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0055 0.0024 0.0024
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0023 0.0004 0.0005
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0019 0.0002 0.0032
Schistosoma mansoni DNA topoisomerase II 0.006 0.0027 0.0027
Entamoeba histolytica hypothetical protein 0.03 0.0175 0.4701
Toxoplasma gondii target of rapamycin (TOR), putative 0.0037 0.0013 0.0011
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0164 0.0091 0.0091
Echinococcus granulosus Regulator of G protein signaling 20 0.0021 0.0003 0.0003
Trypanosoma brucei DNA polymerase kappa, putative 0.0081 0.004 0.0054
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0017 0.0001 0.0001
Brugia malayi ORL1-like opioid receptor 0.0018 0.0001 0.0001
Echinococcus granulosus g protein coupled receptor 0.0018 0.0001 0.0001
Leishmania major alpha glucosidase II subunit, putative 0.005 0.0021 0.0027
Loa Loa (eye worm) oxidoreductase 0.002 0.0003 0.0003
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0075 0.0036 0.0036
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0033 0.0044
Echinococcus granulosus jun protein 0.0086 0.0043 0.0043
Brugia malayi bHLH-PAS transcription factor 0.0224 0.0128 0.0128
Trichomonas vaginalis conserved hypothetical protein 0.0092 0.0047 0.1258
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0018 0.0001 0.0032
Schistosoma mansoni amine GPCR 0.0018 0.0001 0.0001
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0019 0.0002 0.0032
Schistosoma mansoni hypothetical protein 0.0097 0.005 0.005
Trypanosoma brucei DNA polymerase IV, putative 0.0095 0.0049 0.0065
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Echinococcus granulosus lysosomal alpha glucosidase 0.0162 0.009 0.009
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0003 0.0003
Echinococcus multilocularis ATP binding cassette sub family G 0.0021 0.0003 0.0003
Schistosoma mansoni cathepsin F (C01 family) 0.0018 0.0002 0.0002
Onchocerca volvulus 0.0021 0.0003 0.0064
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0003 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0013 0.0334
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.002 0.0003 0.0024
Onchocerca volvulus 0.002 0.0003 0.0062
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0618 0.0371 1
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0018 0.0001 0.0001
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0003 0.0003
Echinococcus multilocularis ubiquitin specific protease 41 0.0038 0.0014 0.0014
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0014 0.0018
Brugia malayi G protein-coupled receptor 0.0018 0.0001 0.0001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0002 0.003
Loa Loa (eye worm) hypothetical protein 0.0092 0.0047 0.0047
Schistosoma mansoni adenoreceptor 0.0018 0.0001 0.0001
Echinococcus granulosus ATP binding cassette sub family G 0.0021 0.0003 0.0003
Echinococcus granulosus neurogenic locus notch protein 4 0.0021 0.0003 0.0003
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0033 0.0044
Leishmania major quinonoid dihydropteridine reductase 0.002 0.0003 0.0003
Brugia malayi Serotonin receptor 0.0018 0.0001 0.0001
Plasmodium vivax thioredoxin reductase, putative 0.0139 0.0076 0.0074
Loa Loa (eye worm) hypothetical protein 0.0084 0.0042 0.0042
Echinococcus granulosus fmrfamide receptor 0.0018 0.0001 0.0001
Giardia lamblia PHD finger protein 15 0.0029 0.0008 0.017
Brugia malayi hypothetical protein 0.1041 0.0631 0.0631
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0048 0.002 0.0026
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0002
Entamoeba histolytica Ran family GTPase 0.0023 0.0004 0.007
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Trichomonas vaginalis alpha-glucosidase, putative 0.0018 0.0002 0.0032
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0092 0.0047 0.1258
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.002 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.002 0.0003 0.0003
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.002 0.0003 0.0003
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0003 0.0003
Brugia malayi Flap endonuclease-1 0.0028 0.0008 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0007 0.0168
Schistosoma mansoni short-chain dehydrogenase/reductase 0.002 0.0003 0.0003
Brugia malayi putative neuropeptide receptor NPR1 0.0018 0.0001 0.0001
Mycobacterium tuberculosis Probable dehydrogenase 0.0317 0.0185 0.5308
Onchocerca volvulus Bile acid receptor homolog 0.0164 0.0091 0.2006
Mycobacterium tuberculosis Possible ketoacyl reductase 0.002 0.0003 0.0056
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0018 0.0001 0.0001
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0022 0.0004 0.0004
Leishmania major cathepsin L-like protease 0.0018 0.0002 0.0002
Trichomonas vaginalis alpha-glucosidase, putative 0.005 0.0021 0.0549
Brugia malayi GRF zinc finger family protein 0.0067 0.0031 0.0031
Onchocerca volvulus 0.0077 0.0038 0.0834
Schistosoma mansoni neuropeptide f receptor 76f 0.0018 0.0001 0.0001
Leishmania major hypothetical protein, conserved 0.0226 0.013 0.0174
Echinococcus multilocularis Kelch repeat type 1 0.0097 0.005 0.005
Brugia malayi Dopamine receptor 0.0018 0.0001 0.0001
Giardia lamblia Histone acetyltransferase GCN5 0.0165 0.0092 0.244
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0098 0.0051 0.0051
Schistosoma mansoni axis inhibition protein axin 0.0021 0.0003 0.0003
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0001 0.0001
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0077 0.0038 0.0038
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0048 0.002 0.0018
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0098 0.0051 0.0068
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0021 0.0003 0.0075
Trypanosoma cruzi DNA polymerase kappa, putative 0.0102 0.0053 0.0071
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0005 0.0005
Brugia malayi nuclear hormone receptor 0.0164 0.0091 0.0091
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0001 0.0001
Onchocerca volvulus Cathepsin L homolog 0.0018 0.0002 0.0035
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0064 0.003 0.0039
Loa Loa (eye worm) hypothetical protein 0.0063 0.0029 0.0029
Trypanosoma brucei DNA polymerase IV, putative 0.0102 0.0053 0.0071
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.0008 0.0008
Trichomonas vaginalis glucosylceramidase, putative 0.0186 0.0105 0.2813
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0019 0.0002 0.0032
Loa Loa (eye worm) RNA binding protein 0.0069 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0164 0.0091 0.0091
Brugia malayi nuclear hormone receptor family member odr-7 0.0077 0.0038 0.0038
Brugia malayi A-kinase anchor protein 10, precursor 0.0021 0.0003 0.0003
Echinococcus granulosus dna polymerase eta 0.0127 0.0069 0.0069
Onchocerca volvulus Peroxidasin homolog 0.0064 0.003 0.065
Onchocerca volvulus 0.0018 0.0001 0.0032
Schistosoma mansoni apoferritin-2 0.0036 0.0012 0.0012
Loa Loa (eye worm) Notch2 0.0021 0.0003 0.0003
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0098 0.0051 0.0068
Mycobacterium ulcerans DNA polymerase IV 0.0102 0.0053 0.1479
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0217 0.0124 0.0124
Mycobacterium tuberculosis UDP-galactopyranose mutase Glf (UDP-GALP mutase) (NAD+-flavin adenine dinucleotide-requiring enzyme) 0.0581 0.0348 1
Trichomonas vaginalis glucosylceramidase, putative 0.0283 0.0165 0.4432
Entamoeba histolytica hypothetical protein 0.03 0.0175 0.4701
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0018 0.0001 0.0001
Schistosoma mansoni short chain dehydrogenase 0.002 0.0003 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0007 0.0168
Echinococcus granulosus neural cadherin 0.0021 0.0003 0.0003
Mycobacterium leprae Probable oxidoreductase 0.002 0.0003 0.0024
Mycobacterium ulcerans monooxygenase 0.0027 0.0007 0.0141
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0145 0.0079 0.0079
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0026 0.0006 0.0008
Loa Loa (eye worm) hypothetical protein 0.0086 0.0043 0.0043
Echinococcus multilocularis serotonin receptor 0.0018 0.0001 0.0001
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0065 0.003 0.003
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0021 0.0003 0.0028
Brugia malayi Niemann-Pick C1 protein precursor 0.0101 0.0052 0.0052
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0092 0.0047 0.1258
Schistosoma mansoni hypothetical protein 0.007 0.0033 0.0033
Onchocerca volvulus 0.002 0.0003 0.0062
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0048 0.002 0.0026
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0164 0.0091 0.0091
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0092 0.0047 0.0046
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0098 0.0051 0.0068
Trypanosoma brucei short-chain dehydrogenase, putative 0.002 0.0003 0.0003
Onchocerca volvulus 0.0063 0.0029 0.0646
Loa Loa (eye worm) hypothetical protein 0.0021 0.0003 0.0003
Schistosoma mansoni neuropeptide F-like receptor 0.0018 0.0001 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0014 0.0377
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.0033 0.0043
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0038 0.0014 0.0323
Trichomonas vaginalis glucosylceramidase, putative 0.0283 0.0165 0.4432
Schistosoma mansoni short chain dehydrogenase 0.002 0.0003 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0003 0.0075
Echinococcus multilocularis survival motor neuron protein 1 0.1483 0.0903 0.0903
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0002 0.003
Trypanosoma brucei cytochrome P450, putative 0.0047 0.0019 0.0025
Loa Loa (eye worm) hypothetical protein 0.0021 0.0003 0.0003
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0018 0.0001 0.0001
Leishmania major quinonoid dihydropteridine reductase 0.002 0.0003 0.0003
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0164 0.0091 0.0091
Onchocerca volvulus Segment polarity protein dishevelled homolog 0.0018 0.0001 0.0032

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) > 10 uM In vitro inhibitory activity against human Prostaglandin G/H synthase 1 (COX-1) in U-937 cells ChEMBL. 12877584
IC50 (binding) > 10 uM In vitro inhibitory activity against human Prostaglandin G/H synthase 2 (COX-2) in 143982 cells ChEMBL. 12877584
IC50 (binding) > 10 uM In vitro inhibitory activity against human Prostaglandin G/H synthase 1 (COX-1) in U-937 cells ChEMBL. 12877584
IC50 (binding) > 10 uM In vitro inhibitory activity against human Prostaglandin G/H synthase 2 (COX-2) in 143982 cells ChEMBL. 12877584
Inhibition (binding) = 0 % Inhibition of Prostaglandin G/H synthase 2 (COX-2) in human whole blood at 10 microM ChEMBL. 12877584
Inhibition (binding) = 0 % Inhibition of Prostaglandin G/H synthase 2 (COX-2) in human whole blood at 10 microM ChEMBL. 12877584
NT (functional) 0 In vivo anti-inflammatory activity by rat carrageenan paw edema method at 10 mg/kg perorally. ChEMBL. 12877584

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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