Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium vivax | basic transcription factor 3b, putative | 0.0034 | 0.0191 | 0.3677 |
Loa Loa (eye worm) | hypothetical protein | 0.0099 | 0.0924 | 0.1944 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.0506 | 0.056 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0042 | 0.0283 | 0.0595 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0033 | 0.0177 | 0.6944 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0324 | 0.3479 | 0.627 |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.0159 | 0.1611 | 0.3391 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.0506 | 0.056 |
Leishmania major | phosphopantetheinyl transferase-like protein | 0.0026 | 0.0098 | 0.1641 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0042 | 0.0283 | 0.0298 |
Plasmodium vivax | holo-[acyl-carrier-protein] synthase, putative | 0.0026 | 0.0098 | 0.1877 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.004 | 0.0256 | 0.1603 |
Brugia malayi | hypothetical protein | 0.0022 | 0.0057 | 0.01 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0042 | 0.0283 | 0.0298 |
Schistosoma mansoni | cpg binding protein | 0.0038 | 0.0233 | 0.0239 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0042 | 0.0283 | 0.0468 |
Brugia malayi | hypothetical protein | 0.002 | 0.003 | 0.0042 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0042 | 0.0283 | 0.0254 |
Brugia malayi | RNA binding protein | 0.0062 | 0.0506 | 0.1047 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.002 | 0.003 | 0.0062 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0023 | 0.0066 | 0.0416 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.0311 | 0.0331 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0208 | 0.2167 | 0.2514 |
Brugia malayi | steroid hormone receptor | 0.0042 | 0.0283 | 0.0576 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0023 | 0.0066 | 0.0416 |
Brugia malayi | ecdysone receptor | 0.002 | 0.003 | 0.0042 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0028 | 0.0122 | 0.0521 |
Echinococcus granulosus | polycomb protein SCMH1 | 0.0053 | 0.0403 | 0.044 |
Loa Loa (eye worm) | hypothetical protein | 0.0159 | 0.1611 | 0.3391 |
Loa Loa (eye worm) | hypothetical protein | 0.0159 | 0.1611 | 0.3391 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0324 | 0.3479 | 1 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0033 | 0.0177 | 0.5029 |
Schistosoma mansoni | scm-relatedprotein containing 4 mbt domains (sfmbt) | 0.0053 | 0.0403 | 0.044 |
Plasmodium vivax | multidomain scavenger receptor, putative | 0.004 | 0.0256 | 0.4912 |
Mycobacterium leprae | conserved hypothetical protein | 0.004 | 0.0256 | 0.1239 |
Schistosoma mansoni | inositol transporter | 0.0043 | 0.0289 | 0.0305 |
Brugia malayi | Nuclear hormone receptor E75 | 0.002 | 0.003 | 0.0042 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0159 | 0.1611 | 0.3391 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0042 | 0.0283 | 0.0576 |
Loa Loa (eye worm) | hypothetical protein | 0.0091 | 0.0833 | 0.1754 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0311 | 0.0331 |
Schistosoma mansoni | coup transcription factor | 0.0042 | 0.0283 | 0.0298 |
Entamoeba histolytica | hypothetical protein | 0.004 | 0.0256 | 0.0555 |
Echinococcus multilocularis | tumor protein p63 | 0.0705 | 0.7799 | 0.7792 |
Echinococcus multilocularis | geminin | 0.0542 | 0.5957 | 0.5945 |
Onchocerca volvulus | 0.004 | 0.0256 | 0.042 | |
Onchocerca volvulus | 0.004 | 0.0256 | 0.042 | |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.003 | 0.0062 |
Schistosoma mansoni | zinc finger protein | 0.0043 | 0.0288 | 0.0303 |
Brugia malayi | hypothetical protein | 0.004 | 0.0256 | 0.0519 |
Echinococcus granulosus | Polycystic kidney disease protein | 0.004 | 0.0256 | 0.0266 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0289 | 0.0607 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0063 | 0.052 | 0.0492 |
Loa Loa (eye worm) | hypothetical protein | 0.0159 | 0.1611 | 0.3391 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0103 | 0.0974 | 0.111 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.004 | 0.0256 | 0.0124 |
Onchocerca volvulus | 0.0092 | 0.0849 | 0.1516 | |
Brugia malayi | aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase | 0.0092 | 0.0849 | 0.177 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0033 | 0.0177 | 0.3411 |
Echinococcus multilocularis | sodium coupled monocarboxylate transporter 1 | 0.0043 | 0.0289 | 0.026 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.004 | 0.0256 | 0.0266 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0042 | 0.0283 | 0.0576 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0042 | 0.0283 | 0.0298 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0042 | 0.0283 | 0.0298 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0324 | 0.3479 | 0.627 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0071 | 0.0613 | 0.1272 |
Mycobacterium ulcerans | lipase LipD | 0.004 | 0.0256 | 0.1603 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.004 | 0.0256 | 0.0124 |
Schistosoma mansoni | bromodomain containing protein | 0.0134 | 0.1322 | 0.1519 |
Leishmania major | hypothetical protein, conserved | 0.0032 | 0.0166 | 0.5221 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0178 | 0.0175 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0042 | 0.0283 | 0.0298 |
Mycobacterium tuberculosis | Conserved protein | 0.004 | 0.0256 | 0.0951 |
Brugia malayi | hypothetical protein | 0.004 | 0.0256 | 0.052 |
Plasmodium vivax | hypothetical protein, conserved | 0.004 | 0.0256 | 0.4928 |
Plasmodium falciparum | basic transcription factor 3b, putative | 0.0034 | 0.0191 | 0.7485 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0033 | 0.0178 | 0.0149 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0117 | 0.1127 | 0.2372 |
Brugia malayi | ecdysteroid receptor | 0.0042 | 0.0283 | 0.0576 |
Brugia malayi | mbt repeat family protein | 0.0053 | 0.0403 | 0.0831 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0057 | 0.0119 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0324 | 0.3479 | 0.627 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0283 | 0.0595 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0208 | 0.2167 | 0.2144 |
Brugia malayi | nuclear receptor NHR-67 | 0.002 | 0.003 | 0.0042 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0042 | 0.0283 | 0.0576 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0036 | 0.0207 | 0.0209 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.002 | 0.003 | 0.0062 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.004 | 0.0256 | 0.0951 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0033 | 0.0178 | 0.0375 |
Loa Loa (eye worm) | hypothetical protein | 0.0147 | 0.1477 | 0.3108 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0036 | 0.0207 | 0.0209 |
Brugia malayi | beta-lactamase family protein | 0.004 | 0.0256 | 0.0521 |
Schistosoma mansoni | lipoxygenase | 0.0167 | 0.1693 | 0.1957 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0099 | 0.0924 | 0.1051 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.0311 | 0.0282 |
Loa Loa (eye worm) | hypothetical protein | 0.0159 | 0.1611 | 0.3391 |
Echinococcus multilocularis | transcription factor btf3 | 0.0034 | 0.0191 | 0.0162 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.003 | 0.0062 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0042 | 0.0283 | 0.0576 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.004 | 0.0256 | 0.0266 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.002 | 0.003 | 0.0042 |
Schistosoma mansoni | inositol transporter | 0.0043 | 0.0289 | 0.0305 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0256 | 0.0539 |
Onchocerca volvulus | 0.004 | 0.0256 | 0.042 | |
Brugia malayi | nuclear receptor NHR-88 | 0.0042 | 0.0283 | 0.0576 |
Echinococcus multilocularis | sodium:glucose cotransporter 2 | 0.0043 | 0.0289 | 0.026 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.004 | 0.0256 | 0.0227 |
Brugia malayi | hypothetical protein | 0.0136 | 0.1344 | 0.2814 |
Echinococcus granulosus | sodium:glucose cotransporter | 0.0043 | 0.0289 | 0.0305 |
Echinococcus multilocularis | SAM and MBT domain containing protein | 0.0053 | 0.0403 | 0.0375 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0256 | 0.0539 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0022 | 0.0057 | 0.01 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0033 | 0.0177 | 0.5029 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0033 | 0.0177 | 0.4107 |
Echinococcus multilocularis | sodium:myo inositol cotransporter | 0.0043 | 0.0289 | 0.026 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.003 | 0.0062 |
Mycobacterium ulcerans | hypothetical protein | 0.0023 | 0.0066 | 0.0416 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.003 | 0.0062 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.003 | 0.0062 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.002 | 0.003 | 0.0042 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0042 | 0.0283 | 0.0595 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0033 | 0.0178 | 0.0355 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0022 | 0.0057 | 0.0032 |
Brugia malayi | nuclear receptor RXR | 0.002 | 0.003 | 0.0042 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0033 | 0.0177 | 0.0148 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0159 | 0.1611 | 0.3391 |
Entamoeba histolytica | hypothetical protein | 0.0034 | 0.0191 | 0.0366 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0023 | 0.0066 | 0.0416 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0042 | 0.0283 | 0.0595 |
Schistosoma mansoni | lipoxygenase | 0.0238 | 0.2507 | 0.2913 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0324 | 0.3479 | 0.5 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0028 | 0.0122 | 0.4792 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0526 | 0.5768 | 0.5755 |
Plasmodium falciparum | holo-[acyl-carrier-protein] synthase, putative | 0.0026 | 0.0098 | 0.382 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.004 | 0.0256 | 0.0951 |
Onchocerca volvulus | 0.0496 | 0.5435 | 1 | |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0022 | 0.0057 | 0.0027 |
Brugia malayi | Animal haem peroxidase family protein | 0.0159 | 0.1611 | 0.3378 |
Echinococcus multilocularis | L aminoadipate semialdehyde | 0.0092 | 0.0849 | 0.0822 |
Echinococcus granulosus | dnaJ subfamily B | 0.0456 | 0.4978 | 0.5819 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0028 | 0.0122 | 0.2354 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0099 | 0.0924 | 0.1051 |
Brugia malayi | Animal haem peroxidase family protein | 0.0159 | 0.1611 | 0.3378 |
Chlamydia trachomatis | holo [acyl-carrier protein] synthase | 0.0026 | 0.0098 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0262 | 0.2777 | 0.5844 |
Echinococcus granulosus | tumor protein p63 | 0.0705 | 0.7799 | 0.9137 |
Trypanosoma cruzi | transcription factor btf3, putative | 0.0034 | 0.0191 | 0.514 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0066 | 0.014 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0042 | 0.0283 | 0.0576 |
Echinococcus multilocularis | zinc finger protein | 0.0043 | 0.0288 | 0.0259 |
Echinococcus granulosus | sodium coupled monocarboxylate transporter 1 | 0.0043 | 0.0289 | 0.0305 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0526 | 0.5768 | 0.5755 |
Onchocerca volvulus | Dual oxidase homolog | 0.0159 | 0.1611 | 0.2927 |
Mycobacterium ulcerans | 4'-phosphopantetheinyl transferase | 0.0026 | 0.0098 | 0.061 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.002 | 0.003 | 0.0062 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0262 | 0.2777 | 0.3231 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.004 | 0.0256 | 0.0267 |
Onchocerca volvulus | 0.004 | 0.0256 | 0.0418 | |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0042 | 0.0283 | 0.0595 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0238 | 0.2507 | 0.2913 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0159 | 0.1611 | 0.3391 |
Brugia malayi | Nuclear hormone receptor E75 | 0.002 | 0.003 | 0.0042 |
Onchocerca volvulus | Peroxidasin homolog | 0.0159 | 0.1611 | 0.2927 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0324 | 0.3479 | 0.627 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0283 | 0.0595 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0045 | 0.0311 | 0.0635 |
Echinococcus multilocularis | Polycystic kidney disease protein | 0.004 | 0.0256 | 0.0227 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0042 | 0.0283 | 0.0595 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0178 | 0.0375 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0042 | 0.0283 | 0.0254 |
Loa Loa (eye worm) | ICD-1 protein | 0.0034 | 0.0191 | 0.0402 |
Schistosoma mansoni | transcription factor btf3 | 0.0034 | 0.0191 | 0.019 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0283 | 0.0595 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0613 | 0.1289 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0033 | 0.0177 | 0.1675 |
Echinococcus granulosus | GPCR family 2 | 0.0033 | 0.0178 | 0.0175 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0178 | 0.0175 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0104 | 0.0987 | 0.2061 |
Onchocerca volvulus | 0.0159 | 0.1611 | 0.2927 | |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.003 | 0.0062 |
Mycobacterium ulcerans | hypothetical protein | 0.004 | 0.0256 | 0.1603 |
Trypanosoma cruzi | transcription factor btf3, putative | 0.0034 | 0.0191 | 0.514 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0068 | 0.0574 | 1 |
Echinococcus granulosus | histone acetyltransferase MYST2 | 0.006 | 0.0486 | 0.0537 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0042 | 0.0283 | 0.0576 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0033 | 0.0177 | 0.1675 |
Brugia malayi | Animal haem peroxidase family protein | 0.0159 | 0.1611 | 0.3378 |
Loa Loa (eye worm) | hypothetical protein | 0.0104 | 0.0987 | 0.2077 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0022 | 0.0057 | 0.0119 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0033 | 0.0177 | 0.0148 |
Brugia malayi | Sodium:solute symporter family protein | 0.0043 | 0.0289 | 0.0589 |
Trypanosoma cruzi | ISWI complex protein | 0.0032 | 0.0166 | 0.3222 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.004 | 0.0256 | 0.0266 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0283 | 0.0595 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.004 | 0.0256 | 0.0266 |
Echinococcus granulosus | methyl CpG binding domain protein 2 | 0.0036 | 0.0207 | 0.0209 |
Brugia malayi | beta-lactamase | 0.004 | 0.0256 | 0.0521 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0033 | 0.0177 | 0.0148 |
Brugia malayi | nuclear hormone receptor | 0.002 | 0.003 | 0.0042 |
Schistosoma mansoni | loxhd1 | 0.004 | 0.0256 | 0.0266 |
Schistosoma mansoni | thyroid hormone receptor | 0.0042 | 0.0283 | 0.0298 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0066 | 0.0416 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0066 | 0.0416 |
Loa Loa (eye worm) | beta-lactamase | 0.004 | 0.0256 | 0.0539 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0066 | 0.014 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0117 | 0.1127 | 0.2372 |
Loa Loa (eye worm) | hypothetical protein | 0.0159 | 0.1611 | 0.3391 |
Brugia malayi | hypothetical protein | 0.0159 | 0.1611 | 0.3378 |
Schistosoma mansoni | rab6-interacting | 0.004 | 0.0256 | 0.0266 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0042 | 0.0283 | 0.0298 |
Loa Loa (eye worm) | hypothetical protein | 0.0085 | 0.0768 | 0.1615 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0023 | 0.0066 | 0.0247 |
Trypanosoma cruzi | ISWI complex protein | 0.0032 | 0.0166 | 0.3222 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0032 | 0.0167 | 0.0351 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0324 | 0.3479 | 0.627 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0063 | 0.052 | 0.0577 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.0311 | 0.0282 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0057 | 0.0119 |
Brugia malayi | hypothetical protein | 0.0022 | 0.0057 | 0.01 |
Mycobacterium tuberculosis | Probable hydrolase | 0.004 | 0.0256 | 0.0951 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.004 | 0.0256 | 0.0227 |
Echinococcus multilocularis | histone acetyltransferase MYST2 | 0.006 | 0.0486 | 0.0458 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0033 | 0.0177 | 0.4107 |
Echinococcus granulosus | L aminoadipate semialdehyde | 0.0092 | 0.0849 | 0.0964 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0256 | 0.0266 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.004 | 0.0256 | 0.0124 |
Toxoplasma gondii | ABC1 family protein | 0.004 | 0.0256 | 0.3331 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.0506 | 0.056 |
Wolbachia endosymbiont of Brugia malayi | 4'-phosphopantetheinyl transferase | 0.0026 | 0.0098 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0042 | 0.0283 | 0.0576 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0042 | 0.0283 | 0.0576 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.004 | 0.0256 | 0.0951 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0042 | 0.0283 | 0.0254 |
Leishmania major | basic transcription factor 3a, putative | 0.0034 | 0.0191 | 0.6573 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0122 | 0.0258 |
Echinococcus granulosus | RUN | 0.004 | 0.0256 | 0.0266 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0238 | 0.2507 | 0.2485 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.003 | 0.0062 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0042 | 0.0283 | 0.0254 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0324 | 0.3479 | 0.627 |
Brugia malayi | hypothetical protein | 0.0028 | 0.0122 | 0.0238 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.0506 | 0.056 |
Mycobacterium leprae | conserved hypothetical protein | 0.0026 | 0.0098 | 0.0203 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0043 | 0.0292 | 0.0614 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0042 | 0.0283 | 0.0298 |
Loa Loa (eye worm) | hypothetical protein | 0.0159 | 0.1611 | 0.3391 |
Brugia malayi | Bromodomain containing protein | 0.008 | 0.071 | 0.1477 |
Schistosoma mansoni | hypothetical protein | 0.0542 | 0.5957 | 0.697 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0023 | 0.0066 | 0.0416 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.002 | 0.003 | 0.0042 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0062 | 0.0506 | 0.1065 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0256 | 0.0538 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0104 | 0.0987 | 0.2061 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0158 | 0.1599 | 1 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0126 | 0.1237 | 0.1211 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.006 | 0.0486 | 0.0537 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0456 | 0.4978 | 0.4963 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.004 | 0.0256 | 0.0521 |
Schistosoma mansoni | thyroid hormone receptor | 0.0042 | 0.0283 | 0.0298 |
Trypanosoma brucei | ISWI complex protein | 0.0032 | 0.0166 | 0.4283 |
Schistosoma mansoni | aminoadipate-semialdehyde dehydrogenase | 0.0092 | 0.0849 | 0.0964 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0042 | 0.0283 | 0.0576 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0033 | 0.0177 | 0.0174 |
Mycobacterium tuberculosis | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) | 0.0033 | 0.0177 | 0.0658 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0022 | 0.0057 | 0.01 |
Schistosoma mansoni | cpg binding protein | 0.0032 | 0.0167 | 0.0161 |
Loa Loa (eye worm) | hypothetical protein | 0.0159 | 0.1611 | 0.3391 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0486 | 0.1024 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0042 | 0.0283 | 0.0468 |
Schistosoma mansoni | hypothetical protein | 0.0321 | 0.345 | 0.4022 |
Loa Loa (eye worm) | hypothetical protein | 0.0159 | 0.1611 | 0.3391 |
Echinococcus granulosus | suppression of tumorigenicity 18 protein | 0.006 | 0.0486 | 0.0537 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0075 | 0.0654 | 0.0626 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.0158 | 0.1599 | 1 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0053 | 0.041 | 0.0845 |
Schistosoma mansoni | cpg binding protein | 0.0038 | 0.0233 | 0.0239 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0042 | 0.0283 | 0.0254 |
Loa Loa (eye worm) | hypothetical protein | 0.0159 | 0.1611 | 0.3391 |
Echinococcus multilocularis | polycomb protein SCMH1 | 0.0053 | 0.0403 | 0.0375 |
Brugia malayi | Pre-SET motif family protein | 0.0436 | 0.4752 | 1 |
Brugia malayi | nuclear hormone receptor | 0.0042 | 0.0283 | 0.0576 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0033 | 0.0177 | 0.0148 |
Loa Loa (eye worm) | RNA binding protein | 0.0062 | 0.0506 | 0.1065 |
Schistosoma mansoni | zinc finger protein | 0.0032 | 0.0166 | 0.016 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.003 | 0.0062 |
Brugia malayi | C2-HC type zinc finger protein C.e-MyT1 | 0.006 | 0.0486 | 0.1006 |
Schistosoma mansoni | survival motor neuron protein | 0.0053 | 0.041 | 0.0447 |
Entamoeba histolytica | hypothetical protein | 0.004 | 0.0256 | 0.0555 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0042 | 0.0283 | 0.0576 |
Loa Loa (eye worm) | hypothetical protein | 0.0159 | 0.1611 | 0.3391 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.004 | 0.0256 | 0.0951 |
Onchocerca volvulus | 0.0042 | 0.0283 | 0.0468 | |
Schistosoma mansoni | polycystin 1-related | 0.004 | 0.0256 | 0.0266 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.004 | 0.0256 | 0.0951 |
Echinococcus multilocularis | cpg binding protein | 0.0038 | 0.0233 | 0.0204 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0104 | 0.0987 | 0.2077 |
Brugia malayi | Isocitrate dehydrogenase | 0.0033 | 0.0177 | 0.0354 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0158 | 0.1599 | 0.5931 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0066 | 0.012 |
Entamoeba histolytica | hypothetical protein | 0.004 | 0.0256 | 0.0555 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0042 | 0.0283 | 0.0298 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0042 | 0.0283 | 0.0254 |
Mycobacterium tuberculosis | holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie | 0.0026 | 0.0098 | 0.0362 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0022 | 0.0057 | 0.0032 |
Brugia malayi | isocitrate dehydrogenase | 0.0033 | 0.0177 | 0.0354 |
Echinococcus granulosus | sodium:glucose cotransporter 2 | 0.0043 | 0.0289 | 0.0305 |
Schistosoma mansoni | hypothetical protein | 0.0043 | 0.0292 | 0.0308 |
Mycobacterium tuberculosis | Conserved protein | 0.004 | 0.0256 | 0.0951 |
Brugia malayi | PHD-finger family protein | 0.0054 | 0.0414 | 0.0853 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0023 | 0.0066 | 0.0247 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0028 | 0.0122 | 0.1565 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0178 | 0.0175 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0049 | 0.0358 | 0.0329 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0042 | 0.0283 | 0.0298 |
Echinococcus granulosus | tar DNA binding protein | 0.0062 | 0.0506 | 0.056 |
Echinococcus multilocularis | high affinity choline transporter 1 | 0.0387 | 0.4201 | 0.4184 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0042 | 0.0283 | 0.0298 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0042 | 0.0283 | 0.0298 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0042 | 0.0283 | 0.0595 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.004 | 0.0256 | 1 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0262 | 0.2777 | 0.2756 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0057 | 0.0119 |
Echinococcus multilocularis | solute carrier family 5 | 0.0043 | 0.0289 | 0.026 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0052 | 0.0393 | 0.0827 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0022 | 0.0057 | 0.0032 |
Onchocerca volvulus | Huntingtin homolog | 0.0136 | 0.1344 | 0.2432 |
Loa Loa (eye worm) | hypothetical protein | 0.0159 | 0.1611 | 0.3391 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0057 | 0.0119 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0042 | 0.0283 | 0.0298 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0062 | 0.0506 | 0.1047 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0053 | 0.0403 | 0.044 |
Echinococcus multilocularis | methyl CpG binding domain protein 2 | 0.0036 | 0.0207 | 0.0178 |
Echinococcus multilocularis | tar DNA binding protein | 0.0062 | 0.0506 | 0.0478 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.004 | 0.0256 | 1 |
Brugia malayi | GH02984p | 0.0387 | 0.4201 | 0.8838 |
Brugia malayi | hypothetical protein | 0.004 | 0.0256 | 0.0519 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0042 | 0.0283 | 0.0254 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.004 | 0.0256 | 0.0124 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0042 | 0.0283 | 0.0576 |
Schistosoma mansoni | high-affinity choline transporter | 0.0387 | 0.4201 | 0.4905 |
Onchocerca volvulus | 0.0043 | 0.0289 | 0.0479 | |
Onchocerca volvulus | Peroxidase homolog | 0.0159 | 0.1611 | 0.2927 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.007 | 0.06 | 0.0671 |
Onchocerca volvulus | 0.0159 | 0.1611 | 0.2927 | |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0075 | 0.0654 | 0.0734 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 0.0311 | 0.0654 |
Toxoplasma gondii | NAC domain-containing protein | 0.0034 | 0.0191 | 0.1966 |
Trichomonas vaginalis | set domain proteins, putative | 0.0496 | 0.5435 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0026 | 0.0098 | 0.0091 |
Schistosoma mansoni | nuclear hormone receptor | 0.0042 | 0.0283 | 0.0298 |
Toxoplasma gondii | transporter, solute:sodium symporter (SSS) family protein | 0.0043 | 0.0289 | 0.4009 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0256 | 0.0539 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.004 | 0.0256 | 0.1603 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0028 | 0.0122 | 0.4792 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0324 | 0.3479 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0103 | 0.0974 | 0.2049 |
Brugia malayi | Animal haem peroxidase family protein | 0.0159 | 0.1611 | 0.3378 |
Loa Loa (eye worm) | hypothetical protein | 0.0159 | 0.1611 | 0.3391 |
Echinococcus granulosus | cpg binding protein | 0.0038 | 0.0233 | 0.0239 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0049 | 0.0358 | 0.0386 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0049 | 0.0358 | 0.0386 |
Entamoeba histolytica | hypothetical protein | 0.004 | 0.0256 | 0.0555 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0099 | 0.0924 | 0.0897 |
Schistosoma mansoni | myelin transcription factor 1 myt1 | 0.006 | 0.0486 | 0.0537 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0126 | 0.1237 | 0.142 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0063 | 0.052 | 0.887 |
Echinococcus granulosus | sodium:myo inositol cotransporter | 0.0043 | 0.0289 | 0.0305 |
Brugia malayi | beta-NAC-like protein | 0.0034 | 0.0191 | 0.0383 |
Brugia malayi | beta-lactamase family protein | 0.004 | 0.0256 | 0.0521 |
Onchocerca volvulus | 0.0103 | 0.0974 | 0.1747 | |
Brugia malayi | Bromodomain containing protein | 0.0158 | 0.1599 | 0.3352 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0283 | 0.0595 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.003 | 0.0062 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0057 | 0.0119 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0053 | 0.0403 | 0.044 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0159 | 0.1611 | 0.3391 |
Loa Loa (eye worm) | mbt repeat family protein | 0.0053 | 0.0403 | 0.0849 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0178 | 0.0175 |
Schistosoma mansoni | hypothetical protein | 0.0071 | 0.0613 | 0.0686 |
Brugia malayi | TAR-binding protein | 0.0062 | 0.0506 | 0.1047 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.0311 | 0.0331 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0711 | 0.1497 |
Schistosoma mansoni | peroxidasin | 0.0159 | 0.1611 | 0.186 |
Mycobacterium ulcerans | phosphopantetheinyl transferase, PptII | 0.0026 | 0.0098 | 0.061 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0769 | 0.8533 | 1 |
Entamoeba histolytica | transcription factor BTF3, putative | 0.0034 | 0.0191 | 0.0366 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0042 | 0.0283 | 0.0254 |
Onchocerca volvulus | 0.0023 | 0.0066 | 0.0068 | |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0042 | 0.0283 | 0.0576 |
Brugia malayi | Animal haem peroxidase family protein | 0.0159 | 0.1611 | 0.3378 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0526 | 0.5768 | 0.6748 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0769 | 0.8533 | 1 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0033 | 0.0178 | 0.0149 |
Brugia malayi | conserved hypotetical protein | 0.002 | 0.003 | 0.0042 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0324 | 0.3479 | 1 |
Brugia malayi | Blistered cuticle protein 3 | 0.0159 | 0.1611 | 0.3378 |
Trichomonas vaginalis | esterase, putative | 0.004 | 0.0256 | 0.0124 |
Brugia malayi | hypothetical protein | 0.002 | 0.003 | 0.0042 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.004 | 0.0256 | 0.0267 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0033 | 0.0177 | 0.5845 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.004 | 0.0256 | 0.0227 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0042 | 0.0283 | 0.0298 |
Brugia malayi | nuclear receptor NHR-88 | 0.002 | 0.003 | 0.0042 |
Loa Loa (eye worm) | MBCTL1 | 0.006 | 0.0486 | 0.1024 |
Echinococcus multilocularis | suppression of tumorigenicity 18 protein | 0.006 | 0.0486 | 0.0458 |
Echinococcus granulosus | solute carrier family 5 | 0.0043 | 0.0289 | 0.0305 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0256 | 0.0266 |
Echinococcus multilocularis | RUN | 0.004 | 0.0256 | 0.0227 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0166 | 0.016 |
Brugia malayi | tailless protein | 0.002 | 0.003 | 0.0042 |
Mycobacterium leprae | Probable lipase LipE | 0.004 | 0.0256 | 0.1239 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0099 | 0.0924 | 0.1051 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0273 | 0.29 | 0.6095 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.002 | 0.003 | 0.0042 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0256 | 0.0539 |
Brugia malayi | Peroxidasin | 0.0159 | 0.1611 | 0.3378 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0042 | 0.0283 | 0.0298 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.004 | 0.0256 | 0.0951 |
Echinococcus granulosus | peroxidasin | 0.0159 | 0.1611 | 0.186 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0066 | 0.0416 |
Schistosoma mansoni | peroxidasin | 0.0159 | 0.1611 | 0.186 |
Echinococcus granulosus | neuropeptide s receptor | 0.0526 | 0.5768 | 0.6748 |
Onchocerca volvulus | 0.0032 | 0.0167 | 0.0254 | |
Onchocerca volvulus | 0.0053 | 0.041 | 0.0704 | |
Onchocerca volvulus | 0.004 | 0.0256 | 0.0418 | |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.0506 | 0.056 |
Loa Loa (eye worm) | hypothetical protein | 0.0136 | 0.1344 | 0.2828 |
Echinococcus granulosus | transcription factor btf3 | 0.0034 | 0.0191 | 0.019 |
Onchocerca volvulus | Peroxidasin homolog | 0.0159 | 0.1611 | 0.2927 |
Brugia malayi | mbt repeat family protein | 0.0053 | 0.0403 | 0.0831 |
Mycobacterium tuberculosis | Conserved protein | 0.004 | 0.0256 | 0.0951 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0436 | 0.4752 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0283 | 0.0595 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0311 | 0.0331 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.004 | 0.0256 | 0.0124 |
Echinococcus granulosus | zinc finger protein | 0.0043 | 0.0288 | 0.0303 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0042 | 0.0283 | 0.0576 |
Echinococcus granulosus | geminin | 0.0542 | 0.5957 | 0.697 |
Schistosoma mansoni | hypothetical protein | 0.0542 | 0.5957 | 0.697 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0324 | 0.3479 | 0.627 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.003 | 0.0062 |
Loa Loa (eye worm) | hypothetical protein | 0.0387 | 0.4201 | 0.884 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.003 | 0.0062 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0283 | 0.0595 |
Loa Loa (eye worm) | TAR-binding protein | 0.0062 | 0.0506 | 0.1065 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0066 | 0.014 |
Echinococcus multilocularis | GPCR, family 2 | 0.0033 | 0.0178 | 0.0149 |
Onchocerca volvulus | Chorion peroxidase homolog | 0.0159 | 0.1611 | 0.2927 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0033 | 0.0177 | 0.0174 |
Brugia malayi | CXXC zinc finger family protein | 0.0032 | 0.0167 | 0.0332 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0042 | 0.0283 | 0.0298 |
Loa Loa (eye worm) | hypothetical protein | 0.0273 | 0.29 | 0.6103 |
Echinococcus granulosus | high affinity choline transporter 1 | 0.0387 | 0.4201 | 0.4905 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.004 | 0.0256 | 0.0267 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0256 | 0.0539 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0042 | 0.0283 | 0.0595 |
Loa Loa (eye worm) | doublecortin family protein | 0.004 | 0.0256 | 0.0538 |
Echinococcus multilocularis | peroxidasin | 0.0159 | 0.1611 | 0.1586 |
Loa Loa (eye worm) | hypothetical protein | 0.0159 | 0.1611 | 0.3391 |
Schistosoma mansoni | hypothetical protein | 0.0053 | 0.041 | 0.0447 |
Brugia malayi | hypothetical protein | 0.0262 | 0.2777 | 0.5836 |
Onchocerca volvulus | Huntingtin homolog | 0.0136 | 0.1344 | 0.2432 |
Trypanosoma brucei | transcription factor BTF3, putative | 0.0034 | 0.0191 | 0.5901 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0037 | 0.0222 | 0.0466 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0033 | 0.0178 | 0.0355 |
Brugia malayi | Cytochrome P450 family protein | 0.0052 | 0.0393 | 0.0809 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0769 | 0.8533 | 0.8529 |
Schistosoma mansoni | sodium/solute symporter | 0.0043 | 0.0289 | 0.0305 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0255 | 0.2696 | 1 |
Echinococcus granulosus | SAM and MBT domain containing protein | 0.0053 | 0.0403 | 0.044 |
Brugia malayi | Doublecortin family protein | 0.004 | 0.0256 | 0.0519 |
Onchocerca volvulus | 0.0053 | 0.0403 | 0.0692 | |
Mycobacterium ulcerans | beta-lactamase | 0.004 | 0.0256 | 0.1603 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0256 | 0.0538 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.004 | 0.0256 | 0.0227 |
Loa Loa (eye worm) | DR-78 | 0.002 | 0.003 | 0.0062 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0033 | 0.0178 | 0.0175 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0033 | 0.0177 | 0.0148 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.003 | 0.0062 |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.0849 | 0.1787 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0324 | 0.3479 | 0.627 |
Trypanosoma brucei | hypothetical protein, conserved | 0.004 | 0.0256 | 1 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0033 | 0.0178 | 0.0175 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.004 | 0.0256 | 0.0539 |
Brugia malayi | Pre-SET motif family protein | 0.0063 | 0.052 | 0.1077 |
Onchocerca volvulus | 0.0063 | 0.052 | 0.0908 | |
Brugia malayi | MH2 domain containing protein | 0.0117 | 0.1127 | 0.2357 |
Onchocerca volvulus | Polycomb protein Sfmbt homolog | 0.0053 | 0.0403 | 0.0692 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.003 | 0.0062 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0063 | 0.052 | 0.0577 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0042 | 0.0283 | 0.0576 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0042 | 0.0283 | 0.0576 |
Plasmodium vivax | SET domain protein, putative | 0.0063 | 0.052 | 1 |
Onchocerca volvulus | 0.0159 | 0.1611 | 0.2927 | |
Leishmania major | hypothetical protein, conserved | 0.0028 | 0.0122 | 0.2949 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0066 | 0.012 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0311 | 0.0331 |
Leishmania major | hypothetical protein, conserved | 0.004 | 0.0256 | 1 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0033 | 0.0177 | 0.0373 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0042 | 0.0283 | 0.0254 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0403 | 0.0849 |
Echinococcus granulosus | FTZ F1 alpha | 0.0042 | 0.0283 | 0.0298 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0042 | 0.0283 | 0.0468 |
Loa Loa (eye worm) | hypothetical protein | 0.0159 | 0.1611 | 0.3391 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0256 | 0.0539 |
Plasmodium falciparum | LCCL domain-containing protein | 0.004 | 0.0256 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0136 | 0.1344 | 0.2828 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0066 | 0.012 |
Brugia malayi | nuclear receptor RXR | 0.0022 | 0.0057 | 0.01 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0042 | 0.0283 | 0.0298 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0042 | 0.0283 | 0.0595 |
Schistosoma mansoni | hypothetical protein | 0.0456 | 0.4978 | 0.5819 |
Schistosoma mansoni | rab6-interacting | 0.004 | 0.0256 | 0.0266 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0042 | 0.0283 | 0.0298 |
Onchocerca volvulus | Peroxidase homolog | 0.0159 | 0.1611 | 0.2927 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Km (binding) | = 3.9 uM | Apparent binding constant for purified human kidney TPMT | ChEMBL. | 3950915 |
Km (binding) | = 3.9 uM | Apparent binding constant for purified human kidney TPMT | ChEMBL. | 3950915 |
logP (ADMET) | = 2.52 | Partition coefficient (logP) | ChEMBL. | 3882967 |
Potency (functional) | 27.5357 uM | PubChem BioAssay: Tox21. qHTS assay to identify small molecule agonists of the AP-1 signaling pathway. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 27.927 uM | PubChem BioAssay: Tox21. qHTS assay for small molecule activators of the heat shock response signaling pathway. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 49.662 uM | PubChem BioAssay: Tox21. qHTS assay to identify small molecule agonists of the AP-1 signaling pathway. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 54.941 uM | PubChem BioAssay: Tox21. qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 54.941 uM | PubChem BioAssay: Tox21. qHTS assay for small molecule activators of the heat shock response signaling pathway. (Class of assay: confirmatory) | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
2 literature references were collected for this gene.