Detailed information for compound 205643

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 709.726 | Formula: C35H44N5O9P
  • H donors: 7 H acceptors: 8 LogP: 1.95 Rotable bonds: 20
    Rule of 5 violations (Lipinski): 3
  • SMILES: NC(=O)C[C@@H](C(=O)NCCCc1cccc2c1cccc2)NC(=O)C1(CCCCC1)NC(=O)[C@@H](Cc1ccc(cc1)OP(=O)(O)O)NC(=O)C
  • InChi: 1S/C35H44N5O9P/c1-23(41)38-29(21-24-14-16-27(17-15-24)49-50(46,47)48)33(44)40-35(18-5-2-6-19-35)34(45)39-30(22-31(36)42)32(43)37-20-8-12-26-11-7-10-25-9-3-4-13-28(25)26/h3-4,7,9-11,13-17,29-30H,2,5-6,8,12,18-22H2,1H3,(H2,36,42)(H,37,43)(H,38,41)(H,39,45)(H,40,44)(H2,46,47,48)/t29-,30+/m1/s1
  • InChiKey: ATTZUIWVKJIUFV-IHLOFXLRSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens growth factor receptor-bound protein 2 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus granulosus growth factor receptor bound protein 2 Get druggable targets OG5_131257 All targets in OG5_131257
Schistosoma japonicum ko:K04364 growth factor receptor-binding protein 2, putative Get druggable targets OG5_131257 All targets in OG5_131257
Brugia malayi Sex muscle abnormal protein 5 Get druggable targets OG5_131257 All targets in OG5_131257
Schistosoma japonicum Growth factor receptor-bound protein 2, putative Get druggable targets OG5_131257 All targets in OG5_131257
Schistosoma mansoni growth factor receptor-bound protein Get druggable targets OG5_131257 All targets in OG5_131257
Schistosoma mansoni growth factor receptor-bound protein Get druggable targets OG5_131257 All targets in OG5_131257
Loa Loa (eye worm) sex muscle abnormal protein 5 Get druggable targets OG5_131257 All targets in OG5_131257
Echinococcus multilocularis growth factor receptor bound protein 2 Get druggable targets OG5_131257 All targets in OG5_131257
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Leishmania major hypothetical protein, conserved growth factor receptor-bound protein 2 217 aa 200 aa 23.5 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0049 0.0128 0.0205
Schistosoma mansoni hypothetical protein 0.0314 0.1179 0.373
Schistosoma mansoni jumonji/arid domain-containing protein 0.0064 0.0187 0.0592
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0319 0.1196 0.3189
Echinococcus multilocularis neuropeptide receptor A26 0.0394 0.1494 0.3983
Entamoeba histolytica proteasome subunit beta type 6 precursor, putative 0.013 0.0449 0.1416
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.002 0.0013 0.0034
Onchocerca volvulus 0.0049 0.0128 0.0478
Loa Loa (eye worm) hypothetical protein 0.0046 0.0115 0.0185
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0045 0.0113 0.0182
Echinococcus multilocularis serotonin receptor 0.0049 0.0128 0.034
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.029 0.1084 0.4077
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0153 0.0541 0.1713
Loa Loa (eye worm) hypothetical protein 0.0049 0.0128 0.0205
Trypanosoma brucei proteasome beta 3 subunit, putative 0.013 0.0449 0.0721
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0049 0.0128 0.0404
Trypanosoma brucei heat shock protein, putative 0.0046 0.0115 0.0185
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.002 0.0013 0.0034
Echinococcus multilocularis geminin 0.0314 0.1179 0.3142
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase, putative 0.0055 0.015 0.024
Onchocerca volvulus 0.0049 0.0128 0.0478
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0041 0.0095 0.0153
Schistosoma mansoni jun-related protein 0.0051 0.0136 0.0432
Schistosoma mansoni cpg binding protein 0.0023 0.0024 0.0076
Trypanosoma cruzi DNA repair protein, putative 0.0025 0.0032 0.0052
Loa Loa (eye worm) hypothetical protein 0.0029 0.0049 0.0078
Echinococcus multilocularis microtubule associated protein 2 0.0518 0.1983 0.5287
Trichomonas vaginalis heat shock protein, putative 0.0046 0.0115 0.0317
Schistosoma mansoni adenoreceptor 0.0049 0.0128 0.0404
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0153 0.0541 0.0869
Onchocerca volvulus 0.0067 0.0198 0.0744
Plasmodium vivax proteasome subunit beta type-5, putative 0.0662 0.2556 0.5514
Trichomonas vaginalis heat shock protein, putative 0.0046 0.0115 0.0317
Echinococcus granulosus tachykinin peptides receptor 99D 0.0049 0.0128 0.034
Loa Loa (eye worm) hypothetical protein 0.0267 0.0992 0.1592
Onchocerca volvulus Chorion peroxidase homolog 0.0029 0.0049 0.0181
Schistosoma mansoni amine GPCR 0.0049 0.0128 0.0404
Echinococcus multilocularis rho GTPase activating protein 20 0.0085 0.0271 0.0724
Brugia malayi hypothetical protein 0.0047 0.0119 0.0191
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0055 0.0153 0.0409
Plasmodium falciparum proteasome subunit alpha type-4, putative 0.013 0.0449 0.0969
Leishmania major hypothetical protein, conserved 0.0036 0.0078 0.0125
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.013 0.0449 0.0721
Plasmodium falciparum proteasome subunit alpha type-1, putative 0.013 0.0449 0.0969
Trypanosoma cruzi transcription factor btf3, putative 0.0037 0.0081 0.0131
Treponema pallidum NADH oxidase 0.0041 0.0095 0.0171
Loa Loa (eye worm) hypothetical protein 0.0045 0.0113 0.0182
Echinococcus multilocularis tyrosine protein kinase Blk 0.0045 0.0114 0.0303
Echinococcus multilocularis proteasome subunit beta (t family) proteasome (prosome macropain) subunit beta 0.013 0.0449 0.1197
Echinococcus multilocularis musashi 0.002 0.0014 0.0037
Trypanosoma brucei DNA topoisomerase IA, putative 0.0085 0.0271 0.0436
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0065 0.0192 0.0214
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0101 0.0332 0.105
Trypanosoma brucei proteasome beta 7 subunit 0.013 0.0449 0.0721
Echinococcus multilocularis proteasome subunit beta type 6 0.013 0.0449 0.1197
Trypanosoma cruzi C-8 sterol isomerase, putative 0.159 0.6231 1
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0137 0.0476 0.127
Loa Loa (eye worm) hypothetical protein 0.029 0.1084 0.174
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0688 0.2657 0.4265
Brugia malayi Variant SH3 domain containing protein 0.002 0.0014 0.0022
Echinococcus granulosus dnaJ subfamily B 0.0307 0.1149 0.3062
Leishmania major C-8 sterol isomerase-like protein 0.159 0.6231 1
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0045 0.0114 0.0245
Loa Loa (eye worm) hypothetical protein 0.0029 0.0049 0.0078
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0319 0.1196 0.258
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0046 0.0115 0.002
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.029 0.1084 0.174
Brugia malayi proteasome subunit alpha type 4 0.013 0.0449 0.0721
Toxoplasma gondii NAC domain-containing protein 0.0037 0.0081 0.0176
Echinococcus granulosus glycine receptor subunit alpha 1 0.002 0.0013 0.0034
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0041 0.0095 0.0153
Treponema pallidum recombinase A 0.0081 0.0254 0.0516
Loa Loa (eye worm) TYRA-2 protein 0.0049 0.0128 0.0205
Onchocerca volvulus 0.0253 0.0936 0.3521
Brugia malayi Animal haem peroxidase family protein 0.0029 0.0049 0.0078
Trichomonas vaginalis endoplasmin, putative 0.0046 0.0115 0.0317
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0067 0.0198 0.0627
Trypanosoma cruzi Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0046 0.0115 0.0185
Plasmodium vivax proteasome subunit alpha type-4, putative 0.013 0.0449 0.0969
Trypanosoma brucei heat shock protein, putative 0.0046 0.0115 0.0185
Brugia malayi Pre-SET motif family protein 0.0222 0.0815 0.1308
Mycobacterium tuberculosis Two component sensor kinase MprB 0.0046 0.0115 0.002
Trichomonas vaginalis prokaryotic DNA topoisomerase, putative 0.0085 0.0271 0.0813
Loa Loa (eye worm) hypothetical protein 0.0067 0.0198 0.0318
Loa Loa (eye worm) hypothetical protein 0.0049 0.0128 0.0205
Trypanosoma cruzi C-14 sterol reductase, putative 0.0094 0.0306 0.0491
Trypanosoma brucei heat shock protein, putative 0.0046 0.0115 0.0185
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.002 0.0013 0.002
Echinococcus multilocularis neuropeptide Y receptor 0.0049 0.0128 0.034
Schistosoma mansoni RAR-like nuclear receptor 0.029 0.1084 0.343
Echinococcus multilocularis proteasome subunit alpha type 2 0.013 0.0449 0.1197
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0128 0.0404
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0023 0.0026 0.0069
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0065 0.0192 0.0214
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0319 0.1196 0.258
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0032 0.0062 0.0133
Echinococcus multilocularis neuropeptide receptor 0.0049 0.0128 0.034
Leishmania major heat shock protein 83-1 0.0046 0.0115 0.0185
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0045 0.0111 0.0179
Echinococcus granulosus g protein coupled receptor 0.0049 0.0128 0.034
Loa Loa (eye worm) hypothetical protein 0.0067 0.0198 0.0318
Echinococcus multilocularis epidermal growth factor receptor 0.0178 0.064 0.1705
Schistosoma mansoni tyrosine kinase 0.0107 0.0355 0.1125
Brugia malayi Variant SH3 domain containing protein 0.002 0.0014 0.0022
Mycobacterium tuberculosis Hypothetical protein 0.0055 0.015 0.0055
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0094 0.0308 0.082
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0539 0.2068 0.4461
Onchocerca volvulus 0.0049 0.0128 0.0478
Onchocerca volvulus Bile acid receptor homolog 0.029 0.1084 0.4077
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.013 0.0449 0.0721
Toxoplasma gondii proteasome subunit alpha type 1, putative 0.013 0.0449 0.0969
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0319 0.1196 0.192
Schistosoma mansoni tyrosine kinase 0.0331 0.1244 0.3935
Trypanosoma brucei proteasome alpha 2 subunit, putative 0.013 0.0449 0.0721
Loa Loa (eye worm) sex muscle abnormal protein 5 0.016 0.0568 0.0912
Onchocerca volvulus Peroxidasin homolog 0.0029 0.0049 0.0181
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.002 0.0013 0.002
Leishmania major proteasome beta 7 subunit, putative 0.013 0.0449 0.0721
Echinococcus granulosus neuropeptide receptor A26 0.0394 0.1494 0.3983
Loa Loa (eye worm) hypothetical protein 0.0074 0.0226 0.0362
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.013 0.0449 0.0721
Giardia lamblia 20S proteasome alpha subunit 6 0.013 0.0449 0.1393
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0217 0.0795 0.2516
Echinococcus granulosus proteasome subunit beta type 6 0.013 0.0449 0.1197
Trypanosoma brucei membrane transporter protein, putative 0.0036 0.0078 0.0125
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.013 0.0449 0.1421
Schistosoma mansoni tyrosine kinase 0.0055 0.0153 0.0485
Echinococcus granulosus beta LACTamase domain containing family member 0.0067 0.0198 0.0528
Brugia malayi hypothetical protein 0.0049 0.0128 0.0205
Trypanosoma brucei proteasome beta-1 subunit, putative 0.013 0.0449 0.0721
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0662 0.2556 0.7621
Echinococcus granulosus microtubule associated protein 2 0.0518 0.1983 0.5287
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0645 0.2487 0.936
Brugia malayi sulfakinin receptor protein 0.0049 0.0128 0.0205
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0049 0.0128 0.0205
Loa Loa (eye worm) hypothetical protein 0.0049 0.0128 0.0205
Onchocerca volvulus Notchless protein homolog 0.013 0.0449 0.1688
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0021 0.0017 0.0045
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.029 0.1084 0.343
Trypanosoma cruzi trypanothione reductase, putative 0.0041 0.0095 0.0153
Trypanosoma brucei metallo- peptidase, Clan M- Family M48 0.0072 0.022 0.0354
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0049 0.0128 0.0205
Trypanosoma cruzi DNA topoisomerase III, putative 0.0085 0.0271 0.0436
Giardia lamblia Kinase, CMGC GSK 0.0688 0.2657 0.8907
Leishmania major mitochondrial DNA topoisomerase II 0.0933 0.3629 0.5825
Leishmania major proteasome alpha 1 subunit, putative 0.013 0.0449 0.0721
Mycobacterium leprae PROBABLE REPLICATIVE DNA HELICASE DNAB replicative DNA helicase 0.029 0.1082 0.3017
Echinococcus granulosus proteasome prosome macropain subunit alpha 0.013 0.0449 0.1197
Schistosoma mansoni nAChR subunit 0.002 0.0013 0.004
Entamoeba histolytica proteasome subunit beta type 3, putative 0.013 0.0449 0.1416
Brugia malayi Intermediate filament tail domain containing protein 0.002 0.0014 0.0022
Leishmania major proteasome alpha 7 subunit, putative 0.013 0.0449 0.0721
Echinococcus granulosus g-protein coupled receptor 0.0049 0.0128 0.034
Leishmania major heat shock protein 83-1 0.0046 0.0115 0.0185
Echinococcus multilocularis 20S proteasome subunit alpha 6 0.013 0.0449 0.1197
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.013 0.0449 0.0721
Echinococcus multilocularis conserved hypothetical protein 0.0763 0.2953 0.7873
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0371 0.1402 0.3739
Mycobacterium ulcerans proteasome PrcA 0.013 0.0449 0.0779
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0128 0.034
Brugia malayi Sex muscle abnormal protein 5 0.016 0.0568 0.0912
Brugia malayi Melatonin receptor type 1A 0.0049 0.0128 0.0205
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0055 0.0153 0.0409
Echinococcus granulosus tyrosine protein kinase Src42A 0.0042 0.0102 0.0271
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0045 0.0113 0.0359
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.013 0.0449 0.1378
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0789 0.3057 0.6583
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0043 0.0105 0.0168
Brugia malayi Proteasome subunit alpha type 7-1 0.013 0.0449 0.0721
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0049 0.0128 0.0404
Mycobacterium tuberculosis Possible two component sensor kinase 0.0046 0.0115 0.002
Trypanosoma cruzi heat shock protein 90, putative 0.0046 0.0115 0.0185
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0515 0.1971 0.3164
Schistosoma mansoni aldehyde dehydrogenase 0.0065 0.019 0.0602
Echinococcus granulosus DNA topoisomerase 3 beta 1 0.0085 0.0271 0.0724
Trypanosoma cruzi DNA topoisomerase III, putative 0.0085 0.0271 0.0436
Brugia malayi hypothetical protein 0.003 0.0053 0.0086
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0049 0.0128 0.034
Leishmania major heat shock protein 83-1 0.0046 0.0115 0.0185
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.002 0.0013 0.002
Onchocerca volvulus 0.0049 0.0128 0.0478
Schistosoma mansoni opsin-like receptor 0.0049 0.0128 0.0404
Plasmodium vivax hypothetical protein, conserved 0.0046 0.0115 0.0249
Echinococcus granulosus rhodopsin orphan GPCR 0.0049 0.0128 0.034
Leishmania major DNA topoisomerase III, putative 0.0085 0.0271 0.0436
Mycobacterium ulcerans recombinase A 0.0081 0.0254 0.035
Schistosoma mansoni nAChR subunit 0.002 0.0013 0.004
Giardia lamblia Proteasome subunit beta type 7 precursor 0.013 0.0449 0.1393
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0049 0.0128 0.0478
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.013 0.0449 0.1378
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.013 0.0449 0.1416
Onchocerca volvulus 0.0049 0.0128 0.0478
Echinococcus multilocularis Proteasome, subunit alpha beta 0.013 0.0449 0.1197
Loa Loa (eye worm) animal heme peroxidase 0.0029 0.0049 0.0078
Echinococcus granulosus intermediate filament protein 0.002 0.0014 0.0037
Onchocerca volvulus 0.0049 0.0128 0.0478
Onchocerca volvulus 0.0049 0.0128 0.0478
Trichomonas vaginalis CMGC family protein kinase 0.0045 0.0111 0.0303
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.029 0.1084 0.343
Brugia malayi putative neuropeptide receptor NPR1 0.0049 0.0128 0.0205
Plasmodium falciparum endoplasmin, putative 0.0046 0.0115 0.0249
Echinococcus granulosus tyrosine protein kinase Fyn 0.0055 0.0153 0.0409
Plasmodium vivax DNA topoisomerase II, putative 0.0815 0.316 0.6817
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0153 0.0541 0.1443
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.029 0.1084 0.2889
Echinococcus granulosus GA binding protein alpha chain 0.0054 0.0149 0.0397
Echinococcus granulosus mitogen activated protein kinase 0.0045 0.0111 0.0296
Brugia malayi Dopamine receptor 0.0049 0.0128 0.0205
Onchocerca volvulus 0.0067 0.0198 0.0744
Schistosoma mansoni nAChR subunit 0.002 0.0013 0.004
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0128 0.034
Echinococcus granulosus proteasome subunit beta t family 0.013 0.0449 0.1197
Loa Loa (eye worm) hypothetical protein 0.002 0.0013 0.002
Loa Loa (eye worm) hypothetical protein 0.0137 0.0476 0.0764
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0128 0.034
Plasmodium falciparum glycogen synthase kinase 3 0.0688 0.2657 0.5732
Leishmania major DNA topoisomerase ii 0.073 0.2822 0.453
Loa Loa (eye worm) hypothetical protein 0.0049 0.0128 0.0205
Schistosoma mansoni hypothetical protein 0.0021 0.0017 0.0053
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.013 0.0449 0.0721
Schistosoma mansoni tyrosine kinase 0.0178 0.064 0.2024
Giardia lamblia DNA topoisomerase III 0.0085 0.0271 0.0789
Onchocerca volvulus 0.0267 0.0992 0.3731
Brugia malayi hypothetical protein 0.0137 0.0476 0.0764
Brugia malayi hypothetical protein 0.0049 0.0128 0.0205
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.0161 0.0573 0.1235
Toxoplasma gondii histone lysine methyltransferase SET1 0.0046 0.0115 0.0248
Mycobacterium ulcerans dihydrofolate reductase DfrA 0.0047 0.0119 0.0052
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0092 0.03 0.0481
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.013 0.0449 0.1421
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0067 0.0198 0.0104
Onchocerca volvulus Dual oxidase homolog 0.0184 0.0663 0.2494
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0137 0.0476 0.127
Plasmodium vivax proteasome subunit beta type-2, putative 0.0319 0.1196 0.258
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0039 0.0089 0.0143
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0515 0.1971 0.5255
Mycobacterium ulcerans two component sensor kinase MprB 0.0046 0.0115 0.0044
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0662 0.2556 0.2485
Schistosoma mansoni opsin-like receptor 0.0049 0.0128 0.0404
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0662 0.2556 0.4103
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0049 0.0128 0.034
Loa Loa (eye worm) hypothetical protein 0.0049 0.0128 0.0205
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0662 0.2556 0.4103
Brugia malayi CXXC zinc finger family protein 0.0022 0.0019 0.0031
Leishmania major proteasome alpha 3 subunit, putative 0.013 0.0449 0.0721
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0049 0.0128 0.034
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0056 0.0154 0.0248
Onchocerca volvulus 0.0045 0.0113 0.0424
Echinococcus granulosus sodium channel protein 0.0039 0.0089 0.0237
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.013 0.0449 0.1378
Schistosoma mansoni lamin 0.002 0.0014 0.0044
Schistosoma mansoni prokaryotic DNA topoisomerase 0.0085 0.0271 0.0859
Entamoeba histolytica T-complex protein 1 beta subunit, putative 0.0027 0.004 0.012
Echinococcus multilocularis Multi antimicrobial extrusion protein MatE 0.0033 0.0065 0.0174
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0515 0.1971 0.6219
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.002 0.0013 0.0034
Brugia malayi hypothetical protein 0.0049 0.013 0.0208
Loa Loa (eye worm) serotonin transporter b 0.0267 0.0992 0.1592
Trypanosoma cruzi hypothetical protein, conserved 0.0067 0.0198 0.0318
Trypanosoma cruzi sterol C-24 reductase, putative 0.0094 0.0306 0.0491
Loa Loa (eye worm) hypothetical protein 0.0029 0.0049 0.0078
Echinococcus multilocularis growth factor receptor bound protein 2 0.016 0.0568 0.1514
Brugia malayi tailless protein 0.0137 0.0476 0.0764
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0121 0.0414 0.0322
Schistosoma mansoni peroxidasin 0.0029 0.0049 0.0154
Brugia malayi Nuclear hormone receptor-like 1 0.0153 0.0541 0.0869
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.013 0.0449 0.1421
Leishmania major proteasome alpha 2 subunit, putative 0.013 0.0449 0.0721
Schistosoma mansoni hypothetical protein 0.0307 0.1149 0.3635
Echinococcus granulosus chaperonin containing TCP1 subunit 2 beta 0.0027 0.004 0.0106
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0041 0.0095 0.0153
Plasmodium vivax proteasome subunit beta type-3, putative 0.013 0.0449 0.0969
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0662 0.2556 0.4103
Mycobacterium tuberculosis Probable oxidoreductase 0.0151 0.0532 0.0441
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0049 0.0128 0.0404
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0137 0.0476 0.127
Loa Loa (eye worm) TK protein kinase 0.0035 0.0073 0.0118
Giardia lamblia 20S proteasome alpha subunit 7 0.013 0.0449 0.1393
Echinococcus granulosus neuropeptide receptor 0.0049 0.0128 0.034
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.013 0.0449 0.0721
Trypanosoma cruzi 20S proteasome subunit 0.0319 0.1196 0.192
Loa Loa (eye worm) hypothetical protein 0.0049 0.0128 0.0205
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.002 0.0013 0.002
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.002 0.0013 0.002
Schistosoma mansoni jumonji domain containing protein 0.0063 0.0182 0.0576
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0049 0.0128 0.0404
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0515 0.1971 0.5255
Loa Loa (eye worm) ACC-1 protein 0.002 0.0013 0.002
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0101 0.0332 0.105
Brugia malayi Nuclear hormone receptor family member nhr-1 0.029 0.1084 0.174
Trypanosoma cruzi Heat shock protein 83, putative 0.0046 0.0115 0.0185
Mycobacterium ulcerans two component sensor histidine kinase TrcS 0.0046 0.0115 0.0044
Leishmania major CAAX prenyl protease 1, putative,metallo-peptidase, Clan M-, Family M48 0.0072 0.022 0.0354
Mycobacterium tuberculosis Conserved protein 0.0067 0.0198 0.0104
Schistosoma mansoni growth factor receptor-bound protein 0.016 0.0568 0.1798
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0078 0.0125
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0055 0.0153 0.0409
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0049 0.0128 0.0404
Echinococcus granulosus ecdysone induced protein 78C 0.029 0.1084 0.2889
Brugia malayi hypothetical protein 0.0049 0.0128 0.0205
Plasmodium falciparum ATP-dependent protease subunit ClpQ 0.013 0.0449 0.0969
Echinococcus granulosus allatostatin A receptor 0.0049 0.0128 0.034
Trichomonas vaginalis penicillin-binding protein, putative 0.0067 0.0198 0.058
Loa Loa (eye worm) hypothetical protein 0.029 0.1084 0.174
Trypanosoma brucei PAB1-binding protein , putative 0.0047 0.0119 0.0191
Echinococcus multilocularis neuropeptides capa receptor 0.0049 0.0128 0.034
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0045 0.0111 0.024
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.013 0.0449 0.0721
Leishmania major heat shock protein 83-1 0.0046 0.0115 0.0185
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0049 0.0128 0.0205
Giardia lamblia Proteasome subunit beta type 9 precursor 0.013 0.0449 0.1393
Loa Loa (eye worm) hypothetical protein 0.002 0.0013 0.002
Echinococcus multilocularis subfamily T1A non peptidase ue 0.013 0.0449 0.1197
Loa Loa (eye worm) animal heme peroxidase 0.0029 0.0049 0.0078
Loa Loa (eye worm) hypothetical protein 0.0335 0.1261 0.2024
Loa Loa (eye worm) hypothetical protein 0.0153 0.0541 0.0869
Loa Loa (eye worm) animal heme peroxidase 0.0029 0.0049 0.0078
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.003 0.0052 0.0084
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0128 0.0404
Leishmania major proteasome beta 2 subunit, putative 0.013 0.0449 0.0721
Brugia malayi Serotonin receptor 0.0557 0.2141 0.3436
Toxoplasma gondii hypothetical protein 0.0045 0.0113 0.0245
Echinococcus granulosus tyrosine protein kinase HCK 0.0035 0.0073 0.0196
Plasmodium vivax basic transcription factor 3b, putative 0.0037 0.0081 0.0176
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0515 0.1971 0.6238
Echinococcus multilocularis dihydrofolate reductase 0.0047 0.0119 0.0317
Plasmodium vivax SET domain protein, putative 0.0032 0.0062 0.0133
Entamoeba histolytica DNA topoisomerase III, putative 0.0085 0.0271 0.0854
Brugia malayi hypothetical protein 0.0153 0.0541 0.0869
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0065 0.019 0.0507
Brugia malayi Nuclear hormone receptor family member nhr-40 0.029 0.1084 0.174
Plasmodium vivax thioredoxin reductase, putative 0.0118 0.04 0.0862
Echinococcus granulosus glycine receptor subunit beta 0.002 0.0013 0.0034
Echinococcus granulosus geminin 0.0314 0.1179 0.3142
Trypanosoma cruzi DNA repair protein, putative 0.0025 0.0032 0.0052
Mycobacterium tuberculosis Probable thymidylate synthase ThyA (ts) (TSASE) 0.0115 0.0388 0.0295
Plasmodium falciparum DNA gyrase subunit B 0.0789 0.3057 0.6594
Trichomonas vaginalis sensor histidine kinase, putative 0.0046 0.0115 0.0317
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0049 0.0128 0.034
Echinococcus granulosus glycine receptor subunit beta 0.002 0.0013 0.0034
Loa Loa (eye worm) hypothetical protein 0.0049 0.0128 0.0205
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.029 0.1084 0.174
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.002 0.0014 0.0022
Echinococcus granulosus mitogen activated protein kinase 3 0.0045 0.0111 0.0296
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.029 0.1084 0.174
Trypanosoma brucei ferric reductase transmembrane protein, putative 0.0073 0.0222 0.0356
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0049 0.0128 0.034
Brugia malayi DNA topoisomerase III 0.0085 0.0271 0.0436
Loa Loa (eye worm) hypothetical protein 0.0137 0.0476 0.0764
Schistosoma mansoni neuropeptide F-like receptor 0.0049 0.0128 0.0404
Brugia malayi Dopamine receptor protein 2 0.0049 0.0128 0.0205
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0815 0.316 0.5072
Loa Loa (eye worm) hypothetical protein 0.029 0.1084 0.174
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0049 0.0128 0.0205
Trypanosoma cruzi PAB1-binding protein , putative 0.0047 0.0119 0.0191
Loa Loa (eye worm) hypothetical protein 0.0137 0.0476 0.0764
Schistosoma mansoni tyrosine kinase 0.0023 0.0026 0.0081
Leishmania major proteasome beta 3 subunit, putative 0.013 0.0449 0.0721
Loa Loa (eye worm) hypothetical protein 0.0049 0.0128 0.0205
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0046 0.0115 0.0044
Onchocerca volvulus 0.0049 0.0128 0.0478
Schistosoma mansoni thyroid hormone receptor 0.0385 0.1458 0.4613
Leishmania major hypothetical protein, conserved 0.0036 0.0078 0.0125
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0163 0.058 0.1547
Plasmodium falciparum DNA topoisomerase 3, putative 0.0085 0.0271 0.0586
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.005 0.0108
Loa Loa (eye worm) hypothetical protein 0.0049 0.0128 0.0205
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0137 0.0476 0.179
Trichomonas vaginalis chromobox protein, putative 0.0052 0.0141 0.0397
Loa Loa (eye worm) hypothetical protein 0.029 0.1084 0.174
Loa Loa (eye worm) hypothetical protein 0.159 0.6231 1
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.015 0.0425
Schistosoma mansoni proteasome catalytic subunit 2 (T01 family) 0.013 0.0449 0.1421
Echinococcus multilocularis tyrosine protein kinase Abl 0.0023 0.0026 0.0069
Brugia malayi excitatory GABA receptor EXP-1A 0.002 0.0013 0.002
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0137 0.0476 0.127
Echinococcus granulosus G protein coupled receptor 139 0.0049 0.0128 0.034
Loa Loa (eye worm) hypothetical protein 0.0049 0.0128 0.0205
Brugia malayi hypothetical protein 0.0049 0.0128 0.0205
Toxoplasma gondii aminotransferase, putative 0.0365 0.138 0.2976
Trypanosoma cruzi DNA topoisomerase IA, putative 0.0085 0.0271 0.0436
Trichomonas vaginalis receptor histidine kinase, putative 0.0046 0.0115 0.0317
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.013 0.0449 0.1378
Echinococcus granulosus NCK adaptor protein 0.002 0.0014 0.0036
Schistosoma mansoni neuropeptide receptor 0.0049 0.0128 0.0404
Schistosoma mansoni ets-related 0.0165 0.0587 0.1857
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.002 0.0013 0.002
Onchocerca volvulus 0.0101 0.0332 0.1246
Leishmania major heat shock protein 83-1 0.0046 0.0115 0.0185
Loa Loa (eye worm) hypothetical protein 0.0049 0.0128 0.0205
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0128 0.0404
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.002 0.0013 0.002
Loa Loa (eye worm) animal heme peroxidase 0.0029 0.0049 0.0078
Loa Loa (eye worm) hypothetical protein 0.029 0.1084 0.174
Echinococcus granulosus proteasome subunit alpha type 2 0.013 0.0449 0.1197
Trichomonas vaginalis CMGC family protein kinase 0.0045 0.0111 0.0303
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0045 0.0113 0.0302
Loa Loa (eye worm) hypothetical protein 0.0029 0.005 0.008
Echinococcus granulosus growth factor receptor bound protein 2 0.016 0.0568 0.1514
Echinococcus multilocularis glycine receptor subunit beta 0.002 0.0013 0.0034
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.002 0.0013 0.002
Treponema pallidum replicative DNA helicase (dnaB) 0.029 0.1082 0.2306
Trypanosoma cruzi DNA topoisomerase II, putative 0.073 0.2822 0.453
Mycobacterium ulcerans two component sensor histidine kinase PrrB 0.0046 0.0115 0.0044
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0049 0.0128 0.0205
Leishmania major proteasome beta-1 subunit, putative 0.013 0.0449 0.0721
Trypanosoma cruzi PAB1-binding protein , putative 0.0047 0.0119 0.0191
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0267 0.0992 0.1592
Mycobacterium ulcerans thymidylate synthase 0.0115 0.0388 0.0644
Loa Loa (eye worm) hypothetical protein 0.0045 0.0113 0.0182
Mycobacterium tuberculosis RecA protein (recombinase A) [contains: endonuclease PI-MTUI (MTU RecA intein)]. 0.2333 0.9173 0.9165
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0121 0.0414 0.0932
Toxoplasma gondii 20S proteasome subunit beta 7, putative 0.013 0.0449 0.0969
Brugia malayi nuclear receptor NHR-88 0.029 0.1084 0.174
Loa Loa (eye worm) neuropeptide F receptor 0.0049 0.0128 0.0205
Schistosoma mansoni nAChR subunit 0.002 0.0013 0.004
Echinococcus granulosus orexin receptor type 2 0.0049 0.0128 0.034
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0056 0.0154 0.0333
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0046 0.0115 0.0249
Loa Loa (eye worm) CXXC zinc finger family protein 0.0022 0.0019 0.0031
Brugia malayi Proteasome A-type and B-type family protein 0.013 0.0449 0.0721
Leishmania major proteasome alpha 1 subunit, putative 0.013 0.0449 0.0721
Brugia malayi Steroid receptor seven-up type 2 0.029 0.1084 0.174
Loa Loa (eye worm) hypothetical protein 0.0049 0.0128 0.0205
Brugia malayi hypothetical protein 0.0153 0.0541 0.0869
Leishmania major 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0297 0.111 0.1781
Echinococcus multilocularis jun protein 0.0063 0.0183 0.0488
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0128 0.034
Plasmodium falciparum thioredoxin reductase 0.0041 0.0095 0.0205
Brugia malayi photoreceptor-specific nuclear receptor 0.029 0.1084 0.174
Schistosoma mansoni proteasome subunit beta 4 (T01 family) 0.013 0.0449 0.1421
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0043 0.0105 0.0279
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0045 0.0113 0.0302
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0045 0.0113 0.0182
Loa Loa (eye worm) steroid hormone receptor 0.029 0.1084 0.174
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0041 0.0095 0.0153
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0789 0.3057 0.299
Trypanosoma cruzi proteasome beta 7 subunit, putative 0.013 0.0449 0.0721
Plasmodium falciparum transporter, putative 0.0045 0.0113 0.0245
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0065 0.019 0.0305
Brugia malayi nuclear hormone receptor 0.029 0.1084 0.174
Schistosoma mansoni sodium/chloride dependent transporter 0.0045 0.0113 0.0359
Brugia malayi neuropeptide F receptor 0.0049 0.0128 0.0205
Loa Loa (eye worm) G-protein coupled receptor 0.0049 0.0128 0.0205
Schistosoma mansoni amine GPCR 0.0049 0.0128 0.0404
Trypanosoma cruzi heat shock protein 85, putative 0.0046 0.0115 0.0185
Schistosoma mansoni amine GPCR 0.0232 0.0852 0.2697
Toxoplasma gondii proteasome subunit alpha type 5-2, putative 0.013 0.0449 0.0969
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0137 0.0476 0.127
Giardia lamblia 20S proteasome alpha subunit 1 0.013 0.0449 0.1393
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0137 0.0476 0.127
Echinococcus multilocularis 0.0102 0.0338 0.09
Mycobacterium leprae probable proteasome (alpha subunit) PrcA 0.013 0.0449 0.1042
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0121 0.0414 0.0322
Loa Loa (eye worm) hypothetical protein 0.0049 0.0128 0.0205
Trypanosoma brucei heat shock protein, putative 0.0046 0.0115 0.0185
Schistosoma mansoni growth hormone secretagogue receptor 0.0049 0.0128 0.0404
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0046 0.0115 0.0317
Loa Loa (eye worm) hypothetical protein 0.002 0.0013 0.002
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0063 0.0182 0.0486
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.019 0.0209
Plasmodium vivax DNA topoisomerase 3, putative 0.0085 0.0271 0.0586
Echinococcus granulosus tyrosine protein kinase Src42A 0.0055 0.0153 0.0409
Echinococcus multilocularis dro:myosuppressin receptor 0.0049 0.0128 0.034
Echinococcus granulosus nuclear receptor 2DBD gamma 0.029 0.1084 0.2889
Brugia malayi ecdysteroid receptor 0.029 0.1084 0.174
Brugia malayi proteasome subunit alpha type 2 0.013 0.0449 0.0721
Onchocerca volvulus Peroxidase homolog 0.0029 0.0049 0.0181
Plasmodium vivax proteasome subunit beta type-6, putative 0.013 0.0449 0.0969
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0041 0.0095 0.0254
Echinococcus granulosus glycine receptor subunit alpha 1 0.002 0.0013 0.0034
Loa Loa (eye worm) hypothetical protein 0.0049 0.0128 0.0205
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0041 0.0095 0.0153
Schistosoma mansoni heat shock protein 0.0046 0.0115 0.0365
Echinococcus granulosus histone lysine methyltransferase setb 0.0032 0.0062 0.0164
Echinococcus granulosus g protein coupled receptor 0.0049 0.0128 0.034
Schistosoma mansoni alpha-1 adrenergic receptor 0.0049 0.0128 0.0404
Loa Loa (eye worm) hypothetical protein 0.0061 0.0176 0.0283
Echinococcus multilocularis GA binding protein alpha chain 0.0054 0.0149 0.0397
Mycobacterium tuberculosis Probable esterase LipL 0.0067 0.0198 0.0104
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0049 0.0128 0.034
Brugia malayi RE15519p 0.0049 0.0128 0.0205
Loa Loa (eye worm) proteasome subunit alpha type 6 0.013 0.0449 0.0721
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.013 0.0449 0.0721
Loa Loa (eye worm) hypothetical protein 0.0267 0.0992 0.1592
Loa Loa (eye worm) hypothetical protein 0.0049 0.0128 0.0205
Schistosoma mansoni neuropeptide receptor 0.0049 0.0128 0.0404
Plasmodium vivax hypothetical protein, conserved 0.0045 0.0113 0.0245
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.002 0.0013 0.002
Loa Loa (eye worm) TK protein kinase 0.0045 0.0114 0.0183
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0041 0.0095 0.0205
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.013 0.0449 0.1416
Loa Loa (eye worm) TOPoisomerase family member 0.0815 0.316 0.5072
Loa Loa (eye worm) latrophilin receptor protein 2 0.0029 0.005 0.008
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0688 0.2657 0.8409
Mycobacterium leprae conserved hypothetical protein 0.0067 0.0198 0.0259
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.013 0.0449 0.1378
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0515 0.1971 0.4252
Trichomonas vaginalis D-aminoacylase, putative 0.0067 0.0198 0.058
Onchocerca volvulus 0.0029 0.0049 0.0181
Trichomonas vaginalis CMGC family protein kinase 0.0045 0.0111 0.0303
Loa Loa (eye worm) hypothetical protein 0.002 0.0013 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.005 0.0108
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.029 0.1084 0.2889
Brugia malayi ecdysone receptor 0.0137 0.0476 0.0764
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0815 0.316 0.8424
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0065 0.019 0.0507
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0964 0.3751 1
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0049 0.0128 0.0205
Brugia malayi hypothetical protein 0.0049 0.0128 0.0205
Loa Loa (eye worm) blistered cuticle protein 3 0.0184 0.0663 0.1064
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0371 0.1402 0.2251
Plasmodium vivax hypothetical protein, conserved 0.0067 0.0198 0.0428
Trypanosoma cruzi DNA topoisomerase II, putative 0.073 0.2822 0.453
Loa Loa (eye worm) hypothetical protein 0.0049 0.0128 0.0205
Echinococcus multilocularis tyrosine protein kinase HCK 0.0035 0.0073 0.0196
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0155 0.0546 0.1455
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0078 0.0125
Echinococcus granulosus Nuclear hormone receptor HR96 0.0137 0.0476 0.127
Trypanosoma brucei heat shock protein, putative 0.0046 0.0115 0.0185
Brugia malayi heat shock protein 90 0.0046 0.0115 0.0185
Schistosoma mansoni hypothetical protein 0.0063 0.0184 0.0583
Trichomonas vaginalis Clan MA, family M48, Ste24 endopeptidase-like metallopeptidase 0.0072 0.022 0.065
Leishmania major proteasome beta 2 subunit, putative 0.0319 0.1196 0.192
Trypanosoma cruzi ATP-dependent protease subunit HslV, putative 0.013 0.0449 0.0721
Schistosoma mansoni endoplasmin 0.0046 0.0115 0.0365
Echinococcus multilocularis glycine receptor subunit beta 0.002 0.0013 0.0034
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0027 0.004 0.0126
Brugia malayi nuclear receptor NHR-88 0.0137 0.0476 0.0764
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0155 0.0546 0.1728
Onchocerca volvulus 0.0023 0.0025 0.009
Echinococcus multilocularis insulin receptor 0.0107 0.0355 0.0948
Trypanosoma cruzi sterol C-24 reductase, putative 0.0094 0.0306 0.0491
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0056 0.0154 0.0248
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0121 0.0414 0.0322
Brugia malayi Probable DNA topoisomerase II 0.0815 0.316 0.5072
Loa Loa (eye worm) hypothetical protein 0.0049 0.0128 0.0205
Echinococcus granulosus neuropeptide s receptor 0.0394 0.1494 0.3983
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0041 0.0095 0.0153
Loa Loa (eye worm) hypothetical protein 0.0137 0.0476 0.0764
Loa Loa (eye worm) hypothetical protein 0.0137 0.0476 0.0764
Mycobacterium leprae Probable DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (Type II DNA topoisomerase) 0.0512 0.1962 0.5767
Onchocerca volvulus 0.002 0.0013 0.0045
Trypanosoma brucei proteasome alpha 1 subunit, putative 0.013 0.0449 0.0721
Treponema pallidum sodium- and chloride- dependent transporter 0.0267 0.0992 0.2112
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0319 0.1196 0.3782
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0137 0.0476 0.127
Loa Loa (eye worm) hypothetical protein 0.0049 0.0128 0.0205
Echinococcus granulosus DNA topoisomerase 3 alpha 0.0085 0.0271 0.0724
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0137 0.0476 0.0764
Loa Loa (eye worm) proteasome subunit alpha type 1 0.013 0.0449 0.0721
Trypanosoma cruzi heat shock protein 85, putative 0.0046 0.0115 0.0185
Schistosoma mansoni voltage-gated potassium channel 0.0047 0.0119 0.0378
Trypanosoma cruzi ferric reductase transmembrane protein, putative 0.0073 0.0222 0.0356
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0128 0.0404
Brugia malayi chromobox protein homolog 3 0.0029 0.005 0.008
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0045 0.0113 0.0302
Mycobacterium leprae PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) 0.0115 0.0388 0.085
Echinococcus multilocularis thyroid hormone receptor alpha 0.0385 0.1458 0.3886
Loa Loa (eye worm) hypothetical protein 0.0049 0.0128 0.0205
Trypanosoma brucei proteasome beta 2 subunit, putative 0.013 0.0449 0.0721
Echinococcus granulosus Proteasome subunit alpha type 7 0.013 0.0449 0.1197
Mycobacterium tuberculosis Two component sensory transduction histidine kinase MtrB 0.0046 0.0115 0.002
Loa Loa (eye worm) hypothetical protein 0.0029 0.005 0.008
Leishmania major hs1vu complex proteolytic subunit-like,hs1vu complex proteolytic subunit-like, threonine peptidase, Clan T(1), family T1B 0.013 0.0449 0.0721
Onchocerca volvulus Peroxidasin homolog 0.0029 0.0049 0.0181
Schistosoma mansoni transcription factor btf3 0.0037 0.0081 0.0258
Leishmania major hypothetical protein, conserved 0.0067 0.0198 0.0318
Brugia malayi Dopamine receptor protein 1 0.0049 0.0128 0.0205
Echinococcus granulosus chromobox protein 1 0.0052 0.0141 0.0375
Leishmania major proteasome beta 5 subunit, putative 0.0662 0.2556 0.4103
Echinococcus granulosus rhodopsin orphan GPCR 0.0049 0.0128 0.034
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.002 0.0013 0.002
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.002 0.0013 0.0034
Entamoeba histolytica heat shock protein 90, putative 0.0046 0.0115 0.036
Trypanosoma brucei T-complex protein 1, beta subunit, putative 0.0027 0.004 0.0064
Brugia malayi larval opioid receptor 0.0049 0.0128 0.0205
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0049 0.0128 0.0404
Brugia malayi Nuclear hormone receptor family member nhr-14 0.029 0.1084 0.174
Loa Loa (eye worm) hypothetical protein 0.0049 0.0128 0.0205
Brugia malayi MAP kinase sur-1 0.0045 0.0111 0.0179
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.013 0.0449 0.1416
Leishmania major heat shock protein 83-1 0.0046 0.0115 0.0185
Plasmodium falciparum proteasome subunit alpha type-5, putative 0.013 0.0449 0.0969
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0151 0.0532 0.0441
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0023 0.0026 0.0069
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0049 0.0128 0.034
Brugia malayi SRC-1 0.0055 0.0153 0.0246
Trypanosoma brucei developmentally regulated phosphoprotein 0.0046 0.0115 0.0185
Echinococcus multilocularis G-protein coupled receptor, putative 0.0049 0.0128 0.034
Entamoeba histolytica protein kinase, putative 0.0035 0.0073 0.0227
Trypanosoma brucei Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0046 0.0115 0.0185
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0319 0.1196 0.3189
Schistosoma mansoni proteasome subunit alpha 7 (T01 family) 0.013 0.0449 0.1421
Schistosoma mansoni nuclear hormone receptor 0.0137 0.0476 0.1507
Loa Loa (eye worm) hypothetical protein 0.0045 0.0113 0.0182
Loa Loa (eye worm) hypothetical protein 0.0137 0.0476 0.0764
Echinococcus granulosus sex peptide receptor 0.0049 0.0128 0.034
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0049 0.0128 0.0404
Echinococcus multilocularis DNA topoisomerase 3 beta 1 0.0085 0.0271 0.0724
Loa Loa (eye worm) hypothetical protein 0.0049 0.0128 0.0205
Schistosoma mansoni myosin xvIII 0.0049 0.0128 0.0404
Giardia lamblia DNA topoisomerase III 0.0085 0.0271 0.0789
Plasmodium falciparum proteasome subunit alpha type-2, putative 0.013 0.0449 0.0969
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0297 0.111 0.1781
Brugia malayi jmjC domain containing protein 0.0063 0.0182 0.0292
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0128 0.034
Echinococcus granulosus somatostatin receptor 0.0049 0.0128 0.034
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0057 0.016 0.0256
Trichomonas vaginalis D-aminoacylase, putative 0.0067 0.0198 0.058
Trypanosoma cruzi C-14 sterol reductase, putative 0.0094 0.0306 0.0491
Loa Loa (eye worm) hypothetical protein 0.0067 0.0198 0.0318
Trichomonas vaginalis esterase, putative 0.0067 0.0198 0.058
Schistosoma mansoni Lamin B receptor (ERG24) 0.0094 0.0306 0.0968
Plasmodium falciparum DNA gyrase subunit A 0.1187 0.4636 1
Leishmania major hypothetical protein, conserved 0.0046 0.0115 0.0185
Echinococcus granulosus thymidylate synthase 0.0115 0.0388 0.1033
Onchocerca volvulus Neuropeptide F receptor homolog 0.0049 0.0128 0.0478
Trichomonas vaginalis CMGC family protein kinase 0.0045 0.0111 0.0303
Brugia malayi hypothetical protein 0.0055 0.015 0.024
Echinococcus granulosus g protein coupled receptor 0.0049 0.0128 0.034
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0045 0.0114 0.0245
Trichomonas vaginalis penicillin-binding protein, putative 0.0067 0.0198 0.058
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.013 0.0449 0.1378
Loa Loa (eye worm) hypothetical protein 0.0507 0.194 0.3113
Loa Loa (eye worm) proteasome subunit beta type 2 0.0319 0.1196 0.192
Brugia malayi Tachykinin-like peptides receptor 99D 0.0049 0.0128 0.0205
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.013 0.0449 0.1416
Schistosoma mansoni hypothetical protein 0.0094 0.0308 0.0974
Schistosoma mansoni farnesylated-protein converting enzyme 1 (M48 family) 0.0072 0.022 0.0697
Brugia malayi jmjC domain containing protein 0.0064 0.0187 0.03
Schistosoma mansoni hypothetical protein 0.0029 0.005 0.0157
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0815 0.316 0.8424
Schistosoma mansoni bifunctional dihydrofolate reductase-thymidylate synthase 0.0115 0.0388 0.1227
Echinococcus granulosus serotonin transporter 0.0267 0.0992 0.2644
Plasmodium falciparum proteasome subunit beta type-4 0.013 0.0449 0.0969
Onchocerca volvulus 0.0137 0.0476 0.179
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0049 0.0128 0.0205
Trichomonas vaginalis glutathione reductase, putative 0.0041 0.0095 0.0252
Schistosoma mansoni peroxidasin 0.0029 0.0049 0.0154
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.002 0.0013 0.0034
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.013 0.0449 0.1416
Trypanosoma cruzi Emopamil binding protein, putative 0.0297 0.111 0.1781
Treponema pallidum chemotaxis histidine kinase (cheA) 0.0046 0.0115 0.0215
Schistosoma mansoni tyrosine kinase 0.0107 0.0355 0.1125
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.0161 0.0573 0.1235
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.013 0.0449 0.1378
Echinococcus multilocularis orexin receptor type 2 0.0049 0.0128 0.034
Mycobacterium tuberculosis Probable reductase 0.0121 0.0414 0.0322
Echinococcus granulosus Nuclear hormone receptor HR96 0.0137 0.0476 0.127
Trypanosoma brucei Proteasome subunit A N-terminal signature/Proteasome subunit, putative 0.013 0.0449 0.0721
Chlamydia trachomatis DNA topoisomerase I 0.0085 0.0271 0.0388
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.002 0.0013 0.0034
Leishmania major sterol C-24 reductase, putative 0.0094 0.0306 0.0491
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.013 0.0449 0.0721
Onchocerca volvulus 0.0045 0.0113 0.0424
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.013 0.0449 0.0721
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0319 0.1196 0.192
Loa Loa (eye worm) hypothetical protein 0.0137 0.0476 0.0764
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.013 0.0449 0.1378
Brugia malayi Nuclear hormone receptor family member nhr-19 0.029 0.1084 0.174
Loa Loa (eye worm) hypothetical protein 0.0049 0.0128 0.0205
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.002 0.0013 0.004
Plasmodium vivax proteasome subunit beta type-4, putative 0.013 0.0449 0.0969
Loa Loa (eye worm) hypothetical protein 0.0049 0.0128 0.0205
Echinococcus granulosus neuropeptide Y receptor 0.0049 0.0128 0.034
Echinococcus multilocularis dnaJ subfamily B 0.0307 0.1149 0.3062
Brugia malayi proteasome subunit beta type 1 0.0515 0.1971 0.3164
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0045 0.0113 0.0302
Giardia lamblia Proteasome subunit beta type 3 0.013 0.0449 0.1393
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0128 0.0404
Echinococcus multilocularis neuropeptide FF receptor 2 0.0049 0.0128 0.034
Entamoeba histolytica transcription factor BTF3, putative 0.0037 0.0081 0.0252
Leishmania major heat shock protein 83-1 0.0046 0.0115 0.0185
Toxoplasma gondii proteasome subunit beta type 7 precursor, putative 0.013 0.0449 0.0969
Toxoplasma gondii proteasome subunit 0.013 0.0449 0.0969
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0046 0.0115 0.0044
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0032 0.0062 0.0164
Loa Loa (eye worm) hypothetical protein 0.0045 0.0113 0.0182
Loa Loa (eye worm) hypothetical protein 0.0029 0.0049 0.0078
Toxoplasma gondii proteasome subunit alpha1, putative 0.013 0.0449 0.0969
Schistosoma mansoni proteasome subunit alpha 4 (T01 family) 0.013 0.0449 0.1421
Trichomonas vaginalis prokaryotic DNA topoisomerase, putative 0.0085 0.0271 0.0813
Schistosoma mansoni sodium-dependent amino acid transporter 0.0045 0.0113 0.0359
Entamoeba histolytica calcium-dependent protein kinase 2, putative 0.0137 0.0477 0.1503
Brugia malayi T-complex protein 1, beta subunit 0.0027 0.004 0.0064
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0128 0.0404
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0045 0.0111 0.0179
Mycobacterium leprae Conserved hypothetical protein 0.0855 0.3318 1
Chlamydia trachomatis DNA gyrase subunit A 0.1187 0.4636 1
Chlamydia trachomatis dihydrofolate reductase 0.0047 0.0119 0.0052
Schistosoma mansoni neuropeptide receptor 0.0049 0.0128 0.0404
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0055 0.0153 0.0409
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0107 0.0355 0.0948
Onchocerca volvulus 0.0074 0.0226 0.0846
Loa Loa (eye worm) proteasome subunit alpha type 7-1 0.013 0.0449 0.0721
Brugia malayi Animal haem peroxidase family protein 0.0029 0.0049 0.0078
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0319 0.1196 0.3785
Trichomonas vaginalis DNA topoisomerase II, putative 0.0815 0.316 1
Plasmodium falciparum histone acetyltransferase GCN5 0.0042 0.0099 0.0213
Brugia malayi Proteasome subunit alpha type 1 0.013 0.0449 0.0721
Brugia malayi beta-lactamase family protein 0.0067 0.0198 0.0318
Loa Loa (eye worm) glutathione reductase 0.0118 0.04 0.0642
Entamoeba histolytica hypothetical protein 0.0021 0.0016 0.0046
Trypanosoma cruzi transcription factor btf3, putative 0.0037 0.0081 0.0131
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0645 0.2487 0.936
Echinococcus granulosus glycine receptor subunit alpha 1 0.002 0.0013 0.0034
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.013 0.0449 0.1378
Schistosoma mansoni Tr4/Tr2 (homologue) 0.029 0.1084 0.343
Loa Loa (eye worm) hypothetical protein 0.0101 0.0332 0.0533
Brugia malayi Ets-domain containing protein 0.0054 0.0149 0.0239
Plasmodium falciparum proteasome subunit beta type-7, putative 0.013 0.0449 0.0969
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.002 0.0013 0.002
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0043 0.0105 0.0168
Brugia malayi conserved hypotetical protein 0.0137 0.0476 0.0764
Mycobacterium ulcerans DNA topoisomerase I 0.0085 0.0271 0.0388
Echinococcus multilocularis chromobox protein 1 0.0052 0.0141 0.0375
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0063 0.0183 0.0488
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0645 0.2487 0.936
Schistosoma mansoni proteasome subunit alpha 2 (T01 family) 0.013 0.0449 0.1421
Mycobacterium tuberculosis Conserved protein 0.0046 0.0115 0.002
Leishmania major heat shock protein 83-1 0.0046 0.0115 0.0185
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.002 0.0013 0.004
Echinococcus multilocularis chaperonin containing TCP1, subunit 2 (beta) 0.0027 0.004 0.0106
Echinococcus multilocularis peroxidasin 0.0029 0.0049 0.013
Giardia lamblia 20S proteasome alpha subunit 4 0.013 0.0449 0.1393
Loa Loa (eye worm) hypothetical protein 0.002 0.0013 0.002
Echinococcus granulosus heat shock protein 90 0.0046 0.0115 0.0308
Loa Loa (eye worm) hypothetical protein 0.0049 0.0128 0.0205
Loa Loa (eye worm) hypothetical protein 0.0049 0.0128 0.0205
Leishmania major DNA topoisomerase III, putative 0.0085 0.0271 0.0436
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0046 0.0115 0.002
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0045 0.0114 0.0311
Brugia malayi nuclear hormone receptor 0.0137 0.0476 0.0764
Echinococcus multilocularis epidermal growth factor receptor 0.0331 0.1244 0.3315
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0041 0.0095 0.0205
Onchocerca volvulus 0.0049 0.0128 0.0478
Mycobacterium tuberculosis Probable two component sensor kinase 0.0046 0.0115 0.002
Schistosoma mansoni tyrosine kinase 0.0178 0.064 0.2024
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0045 0.0113 0.0182
Brugia malayi nuclear hormone receptor family member nhr-6 0.0137 0.0476 0.0764
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0688 0.2657 0.7083
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0045 0.0111 0.0179
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0065 0.0192 0.0309
Plasmodium falciparum DNA topoisomerase 2 0.0815 0.316 0.6817
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.013 0.0449 0.1421
Loa Loa (eye worm) hypothetical protein 0.002 0.0013 0.002
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.003 0.0052 0.0084
Brugia malayi Animal haem peroxidase family protein 0.0029 0.0049 0.0078
Schistosoma mansoni chromobox protein 0.0052 0.0141 0.0445
Brugia malayi Nuclear hormone receptor family member nhr-3 0.029 0.1084 0.174
Loa Loa (eye worm) hypothetical protein 0.029 0.1084 0.174
Brugia malayi orphan nuclear receptor NR2E1 0.0137 0.0476 0.0764
Echinococcus granulosus heat shock protein 0.0046 0.0115 0.0308
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.013 0.0449 0.1421
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0055 0.0153 0.0409
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0049 0.0128 0.0404
Brugia malayi Animal haem peroxidase family protein 0.0029 0.0049 0.0078
Echinococcus granulosus transcription factor btf3 0.0037 0.0081 0.0217
Schistosoma mansoni nAChR subunit 0.002 0.0013 0.004
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0039 0.0089 0.0237
Echinococcus granulosus rhodopsin orphan GPCR 0.0049 0.0128 0.034
Loa Loa (eye worm) PDE1B protein 0.0163 0.058 0.0931
Trypanosoma cruzi hypothetical protein, conserved 0.0067 0.0198 0.0318
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0662 0.2556 0.8089
Toxoplasma gondii DNA topoisomerase family protein 0.0085 0.0271 0.0586
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.029 0.1084 0.174
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0045 0.0113 0.0359
Mycobacterium ulcerans two component system membrane associated sensor kinase 0.0046 0.0115 0.0044
Schistosoma mansoni hypothetical protein 0.0029 0.005 0.0157
Trypanosoma cruzi DNA topoisomerase III, putative 0.0085 0.0271 0.0436
Brugia malayi Heterochromatin protein 1 0.0052 0.0141 0.0226
Mycobacterium tuberculosis Two component sensor kinase [second part] 0.0046 0.0115 0.002
Schistosoma mansoni aldehyde dehydrogenase 0.0065 0.019 0.0602
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.013 0.0449 0.1421
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0041 0.0095 0.0153
Onchocerca volvulus 0.0049 0.0128 0.0478
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.002 0.0013 0.0034
Loa Loa (eye worm) hypothetical protein 0.0492 0.1883 0.3022
Echinococcus multilocularis proteasome subunit alpha type 6 0.013 0.0449 0.1197
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0121 0.0414 0.0322
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0065 0.0192 0.0513
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.002 0.0013 0.002
Schistosoma mansoni heat shock protein 0.0046 0.0115 0.0365
Loa Loa (eye worm) dihydrofolate reductase 0.0047 0.0119 0.0191
Schistosoma mansoni tyrosine kinase 0.0175 0.0628 0.1986
Loa Loa (eye worm) hypothetical protein 0.0914 0.3555 0.5705
Echinococcus multilocularis lamin b receptor 0.0094 0.0306 0.0815
Onchocerca volvulus 0.002 0.0013 0.0045
Echinococcus multilocularis sodium and chloride dependent glycine 0.0045 0.0113 0.0302
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.029 0.1084 0.174
Brugia malayi putative neuropeptide receptor 0.0049 0.0128 0.0205
Plasmodium falciparum proteasome subunit alpha type-3, putative 0.013 0.0449 0.0969
Onchocerca volvulus 0.002 0.0013 0.0045
Loa Loa (eye worm) hypothetical protein 0.0045 0.0113 0.0182
Giardia lamblia Histone acetyltransferase GCN5 0.0042 0.0099 0.0201
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0045 0.0113 0.0359
Loa Loa (eye worm) hypothetical protein 0.0063 0.0184 0.0295
Toxoplasma gondii heat shock protein 90, putative 0.0046 0.0115 0.0249
Schistosoma mansoni nck2/grb4 0.002 0.0014 0.0043
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.0046 0.0115 0.0308
Onchocerca volvulus 0.0041 0.0096 0.0357
Loa Loa (eye worm) hypothetical protein 0.0049 0.0128 0.0205
Echinococcus granulosus thioredoxin glutathione reductase 0.0118 0.04 0.1066
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0041 0.0095 0.0205
Loa Loa (eye worm) beta-lactamase 0.0067 0.0198 0.0318
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0427 0.1624 0.1543
Echinococcus granulosus lamin dm0 0.002 0.0014 0.0037
Trypanosoma brucei protein kinase, putative 0.0045 0.0111 0.0179
Echinococcus granulosus dro:myosuppressin receptor 0.0049 0.0128 0.034
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0049 0.0128 0.034
Loa Loa (eye worm) hypothetical protein 0.002 0.0013 0.002
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.029 0.1084 0.174
Loa Loa (eye worm) LGC-31 protein 0.002 0.0013 0.002
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0049 0.0128 0.034
Mycobacterium tuberculosis Probable lipase LipD 0.0067 0.0198 0.0104
Mycobacterium tuberculosis Possible two component sensor kinase TcrY 0.0046 0.0115 0.002
Loa Loa (eye worm) hypothetical protein 0.002 0.0013 0.002
Toxoplasma gondii aldehyde dehydrogenase 0.0065 0.019 0.041
Brugia malayi Fli-1 protein 0.0165 0.0587 0.0942
Onchocerca volvulus 0.002 0.0014 0.005
Plasmodium vivax DNA gyrase subunit A, putative 0.1187 0.4636 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0083 0.0134
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.013 0.0449 0.0721
Loa Loa (eye worm) hypothetical protein 0.0032 0.0062 0.0099
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.002 0.0013 0.004
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0049 0.0128 0.034
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0045 0.0113 0.0182
Trypanosoma cruzi metallo- peptidase, Clan M- Family M48 0.0072 0.022 0.0354
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0041 0.0095 0.0153
Echinococcus multilocularis g-protein coupled receptor 0.0049 0.0128 0.034
Echinococcus multilocularis protein kinase shaggy 0.0688 0.2657 0.7083
Leishmania major heat shock protein 83-1 0.0046 0.0115 0.0185
Echinococcus multilocularis tyrosine protein kinase Srms 0.0045 0.0114 0.0303
Loa Loa (eye worm) hypothetical protein 0.0029 0.0049 0.0078
Loa Loa (eye worm) hypothetical protein 0.002 0.0014 0.0022
Brugia malayi proteasome subunit beta type 3 0.013 0.0449 0.0721
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0045 0.0111 0.0179
Schistosoma mansoni growth factor receptor-bound protein 0.016 0.0568 0.1798
Echinococcus granulosus lamin b receptor 0.0094 0.0306 0.0815
Loa Loa (eye worm) hypothetical protein 0.0813 0.3152 0.5059
Schistosoma mansoni prokaryotic DNA topoisomerase 0.0085 0.0271 0.0859
Wolbachia endosymbiont of Brugia malayi signal transduction histidine kinase and receiver 0.0046 0.0115 0.0044
Brugia malayi nuclear receptor RXR 0.0153 0.0541 0.0869
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.013 0.0449 0.1378
Schistosoma mansoni hypothetical protein 0.0029 0.005 0.0157
Brugia malayi follicle stimulating hormone receptor 0.0049 0.0128 0.0205
Brugia malayi Proteasome A-type and B-type family protein 0.013 0.0449 0.0721
Brugia malayi neuropeptide F receptor 0.0049 0.0128 0.0205
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0031 0.0055 0.0147
Echinococcus multilocularis fmrfamide receptor 0.0049 0.0128 0.034
Echinococcus granulosus tyrosine kinase 0.0045 0.0114 0.0303
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0018 0.0005 0.0013
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0032 0.0062 0.0164
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0045 0.0114 0.0303
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0049 0.0128 0.0205
Trichomonas vaginalis bromodomain-containing protein, putative 0.0045 0.0114 0.0311
Brugia malayi Proteasome A-type and B-type family protein 0.0662 0.2556 0.4103
Plasmodium falciparum proteasome subunit beta type-3, putative 0.013 0.0449 0.0969
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0128 0.0404
Echinococcus granulosus tyrosine protein kinase Blk 0.0045 0.0114 0.0303
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0041 0.0095 0.0153
Loa Loa (eye worm) hypothetical protein 0.002 0.0013 0.002
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.002 0.0013 0.0034
Schistosoma mansoni hypothetical protein 0.0029 0.005 0.0157
Onchocerca volvulus 0.0049 0.0128 0.0478
Leishmania major proteasome alpha 5 subunit, putative,20S proteasome subunit alpha 5, (putative) 0.013 0.0449 0.0721
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0319 0.1196 0.3785
Echinococcus granulosus fmrfamide receptor 0.0049 0.0128 0.034
Echinococcus granulosus neuropeptide Y receptor 0.0049 0.0128 0.034
Trichomonas vaginalis chromobox protein, putative 0.0032 0.0059 0.0136
Loa Loa (eye worm) hypothetical protein 0.0137 0.0476 0.0764
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0137 0.0476 0.179
Brugia malayi thymidylate synthase 0.0115 0.0388 0.0622
Trypanosoma brucei heat shock protein 90, putative 0.0046 0.0115 0.0185
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0688 0.2657 0.4265
Loa Loa (eye worm) proteasome subunit alpha type 2 0.013 0.0449 0.0721
Plasmodium falciparum T-complex protein 1 subunit beta 0.0027 0.004 0.0086
Mycobacterium ulcerans DNA gyrase subunit B 0.0789 0.3057 0.6523
Echinococcus granulosus proteasome subunit beta type 7 0.013 0.0449 0.1197
Loa Loa (eye worm) hypothetical protein 0.0335 0.1261 0.2024
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0045 0.0113 0.0245
Schistosoma mansoni biogenic amine (5HT) receptor 0.0049 0.0128 0.0404
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0055 0.0153 0.0409
Echinococcus multilocularis caax prenyl protease 1 0.0072 0.022 0.0588
Loa Loa (eye worm) DNA topoisomerase III 0.0085 0.0271 0.0436
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0046 0.0115 0.0249
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0515 0.1971 0.4252
Brugia malayi Serotonin receptor 0.0049 0.0128 0.0205
Echinococcus granulosus tyrosine protein kinase Fyn 0.0055 0.0153 0.0409
Mycobacterium tuberculosis Possible two component system response sensor kinase membrane associated PhoR 0.0046 0.0115 0.002
Loa Loa (eye worm) hypothetical protein 0.0049 0.0128 0.0205
Brugia malayi Cation transporter family protein 0.002 0.0013 0.002
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0055 0.0153 0.0409
Loa Loa (eye worm) cytochrome P450 family protein 0.0026 0.0037 0.006
Trypanosoma brucei proteasome beta 6 subunit 0.0515 0.1971 0.3164
Loa Loa (eye worm) hypothetical protein 0.0029 0.0049 0.0078
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0018 0.0005 0.0013
Giardia lamblia DNA topoisomerase II 0.0769 0.2978 1
Brugia malayi G protein-coupled receptor F59B2.13 0.0049 0.0128 0.0205
Echinococcus multilocularis neuropeptides capa receptor 0.0049 0.0128 0.034
Chlamydia trachomatis DNA gyrase subunit A 0.0224 0.0822 0.1601
Loa Loa (eye worm) hypothetical protein 0.0049 0.0128 0.0205
Loa Loa (eye worm) hypothetical protein 0.0049 0.0128 0.0205
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0078 0.0125
Trypanosoma brucei Emopamil binding protein, putative 0.0297 0.111 0.1781
Trichomonas vaginalis chaperonin, putative 0.0027 0.004 0.0076
Echinococcus granulosus tyrosine protein kinase Src64B 0.0055 0.0153 0.0409
Schistosoma mansoni proteasome subunit alpha 3 (T01 family) 0.013 0.0449 0.1421
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.013 0.0449 0.0721
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.013 0.0449 0.0721
Schistosoma mansoni amine GPCR 0.0049 0.0128 0.0404
Loa Loa (eye worm) hypothetical protein 0.002 0.0012 0.002
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0063 0.0182 0.0486
Echinococcus granulosus c src tyrosine kinase 0.0023 0.0026 0.0069
Giardia lamblia NADH oxidase lateral transfer candidate 0.0041 0.0095 0.0189
Mycobacterium ulcerans esterase/lipase LipP 0.0067 0.0198 0.0227
Entamoeba histolytica hypothetical protein 0.0037 0.0081 0.0252
Mycobacterium leprae DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) 0.0047 0.0119 0.0011
Mycobacterium ulcerans lipase LipD 0.0067 0.0198 0.0227
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0153 0.0541 0.1713
Onchocerca volvulus Peroxidase homolog 0.0029 0.0049 0.0181
Onchocerca volvulus 0.0049 0.0128 0.0478
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0297 0.111 0.1781
Leishmania major developmentally regulated phosphoprotein-like protein 0.0046 0.0115 0.0185
Mycobacterium ulcerans two component regulator - sensor kinase 0.0046 0.0115 0.0044
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.002 0.0013 0.004
Trypanosoma cruzi DNA topoisomerase IA, putative 0.0085 0.0271 0.0436
Entamoeba histolytica proteasome subunit beta type 7-B precursor, putative 0.013 0.0449 0.1416
Schistosoma mansoni opsin-like receptor 0.0049 0.0128 0.0404
Brugia malayi acetyltransferase, GNAT family protein 0.0155 0.0546 0.0876
Mycobacterium ulcerans hypothetical protein 0.0067 0.0198 0.0227
Leishmania major basic transcription factor 3a, putative 0.0037 0.0081 0.0131
Schistosoma mansoni sodium/chloride dependent transporter 0.0052 0.0141 0.0446
Brugia malayi Nuclear hormone receptor-like 1 0.0153 0.0541 0.0869
Schistosoma mansoni sodium/chloride dependent transporter 0.0267 0.0992 0.3139
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0065 0.0192 0.0098
Echinococcus multilocularis thymidylate synthase 0.0115 0.0388 0.1033
Brugia malayi nuclear receptor RXR 0.0137 0.0476 0.0764
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0045 0.0113 0.0182
Brugia malayi T-complex protein 1, beta subunit 0.0027 0.004 0.0064
Echinococcus multilocularis sodium and chloride dependent glycine 0.0045 0.0113 0.0302
Trypanosoma cruzi ferric reductase transmembrane protein, putative 0.0073 0.0222 0.0356
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.002 0.0013 0.0034
Onchocerca volvulus 0.0049 0.0128 0.0478
Loa Loa (eye worm) TK/EGFR protein kinase 0.0331 0.1244 0.1996
Loa Loa (eye worm) hypothetical protein 0.0049 0.0128 0.0205
Schistosoma mansoni biogenic amine (5HT) receptor 0.0049 0.0128 0.0404
Loa Loa (eye worm) hypothetical protein 0.029 0.1084 0.174
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.002 0.0013 0.002
Brugia malayi hypothetical protein 0.0049 0.0128 0.0205
Schistosoma mansoni multidrug resistance protein 0.0036 0.0078 0.0246
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0038 0.0085 0.0218
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0081 0.0208
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0163 0.058 0.0931
Echinococcus granulosus 7tm_1 domain containing protein 0.0049 0.0128 0.034
Schistosoma mansoni cpg binding protein 0.0022 0.0019 0.006
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0045 0.0111 0.0179
Brugia malayi nuclear hormone receptor family member odr-7 0.0137 0.0476 0.0764
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0118 0.04 0.0307
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0067 0.0198 0.0318
Schistosoma mansoni thyroid hormone receptor 0.0385 0.1458 0.4613
Trypanosoma brucei membrane transporter protein, putative 0.0036 0.0078 0.0125
Brugia malayi hypothetical protein 0.0049 0.0128 0.0205
Loa Loa (eye worm) endoplasmin 0.0046 0.0115 0.0185
Echinococcus granulosus proteasome prosome macropain 0.0662 0.2556 0.6814
Loa Loa (eye worm) hypothetical protein 0.0029 0.0049 0.0078
Trypanosoma cruzi heat shock protein 85, putative 0.0046 0.0115 0.0185
Onchocerca volvulus 0.0297 0.111 0.4175
Trichomonas vaginalis D-aminoacylase, putative 0.0067 0.0198 0.058
Brugia malayi Pre-SET motif family protein 0.0032 0.0062 0.0099
Mycobacterium tuberculosis Probable lipase LipE 0.0067 0.0198 0.0104
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0049 0.0128 0.034
Echinococcus multilocularis glycine receptor subunit alpha 1 0.002 0.0013 0.0034
Loa Loa (eye worm) neuropeptide F receptor 0.0049 0.0128 0.0205
Brugia malayi intermediate filament protein 0.002 0.0014 0.0022
Loa Loa (eye worm) hypothetical protein 0.0092 0.03 0.0481
Brugia malayi dihydrofolate reductase family protein 0.0047 0.0119 0.0191
Echinococcus multilocularis nAChR subunit 0.002 0.0013 0.0034
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.029 0.1084 0.174
Entamoeba histolytica protein kinase domain containing protein 0.0688 0.2657 0.8408
Loa Loa (eye worm) hypothetical protein 0.0045 0.0113 0.0182
Leishmania major proteasome alpha 7 subunit, putative 0.013 0.0449 0.0721
Echinococcus multilocularis sex peptide receptor 0.0049 0.0128 0.034
Toxoplasma gondii hypothetical protein 0.0045 0.0113 0.0245
Trichomonas vaginalis mercuric reductase, putative 0.0041 0.0095 0.0252
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0047 0.0119 0.0378
Loa Loa (eye worm) DR-78 0.0137 0.0476 0.0764
Giardia lamblia 20S proteasome alpha subunit 3 0.013 0.0449 0.1393
Entamoeba histolytica proteasome subunit alpha type 6, putative 0.013 0.0449 0.1416
Echinococcus multilocularis proteasome (prosome macropain) subunit alpha 0.013 0.0449 0.1197
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0041 0.0095 0.0153
Brugia malayi hypothetical protein 0.0049 0.0128 0.0205
Plasmodium falciparum glutathione reductase 0.0041 0.0095 0.0205
Loa Loa (eye worm) ACC-1 protein 0.002 0.0013 0.002
Leishmania major heat shock protein 83-1 0.0046 0.0115 0.0185
Giardia lamblia Proteasome subunit beta type 2 0.0319 0.1196 0.3935
Schistosoma mansoni tyrosine kinase 0.0175 0.0628 0.1986
Plasmodium vivax proteasome subunit alpha type-6, putative 0.013 0.0449 0.0969
Giardia lamblia Heat shock protein HSP 90-alpha 0.0046 0.0115 0.0258
Loa Loa (eye worm) hypothetical protein 0.0049 0.0128 0.0205
Loa Loa (eye worm) hypothetical protein 0.002 0.0013 0.002
Schistosoma mansoni chromobox protein 0.0052 0.0141 0.0445
Brugia malayi Blistered cuticle protein 3 0.0184 0.0663 0.1064
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0049 0.0128 0.0404
Schistosoma mansoni neuropeptide receptor 0.0049 0.0128 0.0404
Trichomonas vaginalis mismatch repair protein Mlh1C (mutL homolog) 0.0046 0.0115 0.0317
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0054 0.0149 0.0239
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0045 0.0114 0.0303
Mycobacterium tuberculosis Two component sensor histidine kinase PrrB 0.0046 0.0115 0.002
Brugia malayi proteasome subunit alpha type 3 0.013 0.0449 0.0721
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0023 0.0026 0.0081
Schistosoma mansoni tyrosine kinase 0.0055 0.0153 0.0485
Echinococcus granulosus neuropeptides capa receptor 0.0049 0.0128 0.034
Schistosoma mansoni biogenic amine receptor 0.0049 0.0128 0.0404
Toxoplasma gondii DNA topoisomerase domain-containing protein 0.0085 0.0271 0.0586
Loa Loa (eye worm) hypothetical protein 0.0338 0.1274 0.2044
Leishmania major C-14 sterol reductase, putative 0.0094 0.0306 0.0491
Echinococcus multilocularis serotonin transporter 0.0267 0.0992 0.2644
Schistosoma mansoni tyrosine kinase 0.0175 0.0628 0.1986
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0065 0.0192 0.0309
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.0161 0.0573 0.0919
Loa Loa (eye worm) hypothetical protein 0.029 0.1084 0.174
Brugia malayi Nuclear hormone receptor family member nhr-31 0.029 0.1084 0.174
Leishmania major heat shock protein 83-1 0.0046 0.0115 0.0185
Plasmodium falciparum ataxin-2 like protein, putative 0.0047 0.0119 0.0257
Schistosoma mansoni microtubule-associated protein tau 0.0518 0.1983 0.6277
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0062 0.0195
Trypanosoma brucei proteasome alpha 3 subunit, putative 0.013 0.0449 0.0721
Mycobacterium ulcerans putative regultory protein 0.0046 0.0115 0.0044
Loa Loa (eye worm) variant SH3 domain-containing protein 0.002 0.0014 0.0022
Loa Loa (eye worm) hypothetical protein 0.0029 0.0049 0.0078
Echinococcus granulosus rhodopsin orphan GPCR 0.0049 0.0128 0.034
Echinococcus granulosus tm gpcr rhodopsin 0.0049 0.0128 0.034
Schistosoma mansoni endoplasmin 0.0046 0.0115 0.0365
Mycobacterium tuberculosis Probable hydrolase 0.0067 0.0198 0.0104
Echinococcus granulosus caax prenyl protease 1 0.0072 0.022 0.0588
Leishmania major heat shock protein 83-1 0.0046 0.0115 0.0185
Echinococcus granulosus cpg binding protein 0.0023 0.0024 0.0064
Brugia malayi hypothetical protein 0.013 0.0448 0.0719
Loa Loa (eye worm) hypothetical protein 0.002 0.0014 0.0022
Brugia malayi proteasome subunit alpha type 6 0.013 0.0449 0.0721
Echinococcus granulosus 7TM GPCR rhodopsin 0.0049 0.0128 0.034
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0065 0.0192 0.0513
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0041 0.0095 0.0153
Plasmodium vivax ataxin-2 like protein, putative 0.0047 0.0119 0.0257
Loa Loa (eye worm) G-protein coupled receptor 0.0049 0.0128 0.0205
Wolbachia endosymbiont of Brugia malayi recombinase A 0.0081 0.0254 0.035
Echinococcus multilocularis g protein coupled receptor 0.0049 0.0128 0.034
Echinococcus granulosus alpha 1A adrenergic receptor 0.0049 0.0128 0.034
Trypanosoma brucei heat shock protein, putative 0.0046 0.0115 0.0185
Leishmania major heat shock protein 83-1 0.0046 0.0115 0.0185
Schistosoma mansoni nAChR subunit 0.002 0.0013 0.004
Brugia malayi Furin-like cysteine rich region family protein 0.0331 0.1244 0.1996
Mycobacterium ulcerans replicative DNA helicase DnaB 0.029 0.1082 0.2172
Brugia malayi Tyrosine-protein kinase abl-1 0.0023 0.0026 0.0041
Onchocerca volvulus 0.0688 0.2657 1
Echinococcus multilocularis mitogen activated protein kinase 3 0.0045 0.0111 0.0296
Brugia malayi hypothetical protein 0.0137 0.0476 0.0764
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0056 0.0154 0.0412
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0049 0.0128 0.0404
Entamoeba histolytica protein kinase domain containing protein 0.0688 0.2657 0.8408
Echinococcus multilocularis neuropeptide receptor 0.0049 0.0128 0.034
Loa Loa (eye worm) hypothetical protein 0.0049 0.0128 0.0205
Toxoplasma gondii DNA topoisomerase 2, putative 0.0815 0.316 0.6817
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0045 0.0113 0.0182
Loa Loa (eye worm) DNA topoisomerase III beta-1 0.0085 0.0271 0.0436
Echinococcus granulosus lysine specific demethylase 5A 0.0064 0.0187 0.0499
Mycobacterium tuberculosis Two component sensor histidine kinase TrcS 0.0046 0.0115 0.002
Loa Loa (eye worm) hypothetical protein 0.0507 0.194 0.3113
Schistosoma mansoni serine/threonine protein kinase 0.0045 0.0111 0.0352
Toxoplasma gondii proteasome subunit alpha2, protease of the acylase family and NTN hydrolase fold, putative 0.013 0.0449 0.0969
Trypanosoma cruzi proteasome subunit alpha type-1, putative 0.013 0.0449 0.0721
Schistosoma mansoni nuclear hormone receptor 0.029 0.1084 0.343
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.013 0.0449 0.1416
Loa Loa (eye worm) hypothetical protein 0.002 0.0013 0.002
Brugia malayi beta-NAC-like protein 0.0037 0.0081 0.0131
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0029 0.005 0.008
Loa Loa (eye worm) hypothetical protein 0.0049 0.0128 0.0205
Onchocerca volvulus 0.0022 0.0019 0.0069
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0062 0.0195
Brugia malayi bZIP transcription factor family protein 0.0063 0.0183 0.0294
Toxoplasma gondii thioredoxin reductase 0.0118 0.04 0.0862
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.013 0.0449 0.0721
Trypanosoma brucei C-8 sterol isomerase, putative 0.159 0.6231 1
Giardia lamblia Kinase, CMGC GSK 0.0688 0.2657 0.8907
Trichomonas vaginalis two component sensor and regulator histidine kinase bacteria, putative 0.0046 0.0115 0.0317
Loa Loa (eye worm) hypothetical protein 0.002 0.0013 0.002
Leishmania major heat shock protein 83-1 0.0046 0.0115 0.0185
Echinococcus granulosus histone acetyltransferase KAT2B 0.015 0.0529 0.141
Echinococcus multilocularis proteasome (prosome, macropain) 0.0662 0.2556 0.6814
Loa Loa (eye worm) proteasome subunit beta type 3 0.013 0.0449 0.0721
Loa Loa (eye worm) hypothetical protein 0.0047 0.0119 0.0191
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0045 0.0113 0.004
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.013 0.0449 0.0721
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0041 0.0095 0.0153
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0027 0.004 0.0126
Echinococcus granulosus rhodopsin orphan GPCR 0.0049 0.0128 0.034
Onchocerca volvulus Protein ultraspiracle homolog 0.029 0.1084 0.4077
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0045 0.0113 0.0302
Giardia lamblia 20S proteasome alpha subunit 2 0.013 0.0449 0.1393
Echinococcus granulosus thyroid hormone receptor alpha 0.0137 0.0476 0.127
Trypanosoma cruzi T-complex protein 1, beta subunit, putative 0.0027 0.004 0.0064
Trypanosoma cruzi membrane transporter protein, putative 0.0036 0.0078 0.0125
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.013 0.0449 0.0721
Mycobacterium ulcerans sensor kinase from two component regulatory system 0.0046 0.0115 0.0044
Echinococcus granulosus neuropeptides capa receptor 0.0049 0.0128 0.034
Loa Loa (eye worm) hypothetical protein 0.002 0.0013 0.002
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.029 0.1084 0.2889
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0049 0.0128 0.034
Toxoplasma gondii heat shock protein HSP90 0.0046 0.0115 0.0249
Echinococcus multilocularis c src tyrosine kinase 0.0023 0.0026 0.0069
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0688 0.2657 0.5732
Entamoeba histolytica DNA topoisomerase II, putative 0.0815 0.316 1
Mycobacterium tuberculosis Probable sensor protein KdpD 0.0046 0.0115 0.002
Loa Loa (eye worm) hypothetical protein 0.0267 0.0992 0.1592
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.029 0.1084 0.174
Echinococcus multilocularis mitogen activated protein kinase 0.0045 0.0111 0.0296
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.029 0.1084 0.2889
Brugia malayi Cytochrome P450 family protein 0.0026 0.0037 0.006
Brugia malayi proteasome subunit alpha type 1 0.013 0.0449 0.0721
Plasmodium vivax proteasome subunit beta type-1, putative 0.0515 0.1971 0.4252
Plasmodium falciparum heat shock protein 90 0.0046 0.0115 0.0249
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0515 0.1971 0.6236
Trypanosoma brucei heat shock protein, putative 0.0046 0.0115 0.0185
Loa Loa (eye worm) hypothetical protein 0.0492 0.1883 0.3022
Echinococcus granulosus insulin receptor 0.0107 0.0355 0.0948
Trypanosoma brucei proteasome alpha 7 subunit 0.013 0.0449 0.0721
Trichomonas vaginalis chaperonin-60kD, ch60, putative 0.0027 0.004 0.0076
Echinococcus granulosus Proteasome subunit alpha beta 0.013 0.0449 0.1197
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0055 0.0153 0.0409
Entamoeba histolytica acetyltransferase, GNAT family 0.0042 0.0099 0.0307
Trypanosoma cruzi Emopamil binding protein, putative 0.0297 0.111 0.1781
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0045 0.0113 0.0302
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0049 0.0128 0.0404
Leishmania major T-complex protein 1, beta subunit, putative 0.0027 0.004 0.0064
Echinococcus granulosus dihydrofolate reductase 0.0047 0.0119 0.0317
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0049 0.0128 0.0205
Onchocerca volvulus 0.0029 0.0049 0.0181
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0078 0.0125
Echinococcus multilocularis allatostatin A receptor 0.0049 0.0128 0.034
Brugia malayi Nuclear hormone receptor family member nhr-25 0.029 0.1084 0.174
Brugia malayi DNA topoisomerase III beta-1 0.0085 0.0271 0.0436
Echinococcus granulosus chromobox protein 1 0.0052 0.0141 0.0375
Loa Loa (eye worm) hypothetical protein 0.002 0.0013 0.002
Onchocerca volvulus 0.0029 0.0049 0.0181
Brugia malayi glutathione reductase 0.0118 0.04 0.0642
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.002 0.0013 0.002
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0046 0.0115 0.0308
Schistosoma mansoni nuclear receptor nhr-48 0.0137 0.0476 0.1507
Loa Loa (eye worm) hypothetical protein 0.0098 0.0322 0.0517
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0049 0.0128 0.034
Schistosoma mansoni jumonji/arid domain-containing protein 0.0064 0.0187 0.0592
Plasmodium falciparum proteasome subunit beta type-6, putative 0.013 0.0449 0.0969
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.013 0.0449 0.0721
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0041 0.0095 0.0301
Onchocerca volvulus 0.0049 0.0128 0.0478
Schistosoma mansoni hypothetical protein 0.0049 0.0128 0.0404
Echinococcus multilocularis nuclear receptor nhr 48 0.0137 0.0476 0.127
Trichomonas vaginalis sensory transduction histidine kinase, putative 0.0046 0.0115 0.0317
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.029 0.1084 0.2889
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0029 0.005 0.0185
Trypanosoma brucei C-14 sterol reductase, putative 0.0094 0.0306 0.0491
Brugia malayi GnHR receptor homolog 0.0049 0.0128 0.0205
Schistosoma mansoni neuropeptide F-like receptor 0.0049 0.0128 0.0404
Onchocerca volvulus 0.0049 0.013 0.0485
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0933 0.3629 0.5825
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0041 0.0095 0.0153
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0063 0.0183 0.0488
Schistosoma mansoni biogenic amine receptor 0.0049 0.0128 0.0404
Loa Loa (eye worm) acetyltransferase 0.0155 0.0546 0.0876
Loa Loa (eye worm) hypothetical protein 0.002 0.0013 0.002
Echinococcus granulosus biogenic amine 5HT receptor 0.0049 0.0128 0.034
Trypanosoma brucei proteasome subunit alpha type-5, putative 0.013 0.0449 0.0721
Echinococcus granulosus peroxidasin 0.0029 0.0049 0.013
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.002 0.0013 0.002
Brugia malayi Nuclear hormone receptor family member nhr-25 0.029 0.1084 0.174
Loa Loa (eye worm) nuclear receptor NHR-67 0.0137 0.0476 0.0764
Loa Loa (eye worm) hypothetical protein 0.0049 0.0128 0.0205
Brugia malayi ORL1-like opioid receptor 0.0049 0.0128 0.0205
Loa Loa (eye worm) hypothetical protein 0.0137 0.0476 0.0764
Trichomonas vaginalis CMGC family protein kinase 0.0688 0.2657 0.8401
Loa Loa (eye worm) hypothetical protein 0.002 0.0013 0.002
Leishmania major hypothetical protein, conserved 0.0297 0.111 0.1781
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0128 0.034
Echinococcus granulosus multidrug and toxin extrusion protein 2 0.0036 0.0078 0.0208
Echinococcus granulosus nAChR subunit 0.002 0.0013 0.0034
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.013 0.0449 0.1378
Mycobacterium leprae Probable lipase LipE 0.0067 0.0198 0.0259
Leishmania major hypothetical protein, conserved 0.0047 0.0119 0.0191
Onchocerca volvulus 0.002 0.0013 0.0045
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0067 0.0198 0.0104
Trypanosoma brucei recA bacterial DNA recombination protein, putative 0.0025 0.0032 0.0052
Plasmodium vivax T-complex protein 1 subunit beta, putative 0.0027 0.004 0.0086
Echinococcus multilocularis beta LACTamase domain containing family member 0.0067 0.0198 0.0528
Echinococcus multilocularis neuropeptide s receptor 0.0394 0.1494 0.3983
Echinococcus granulosus serotonin receptor 0.0049 0.0128 0.034
Schistosoma mansoni cpg binding protein 0.0023 0.0024 0.0076
Schistosoma mansoni nuclear receptor 0.0137 0.0476 0.1507
Trypanosoma brucei ATP-dependent protease subunit HslV 0.013 0.0449 0.0721
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0056 0.0154 0.0333
Mycobacterium ulcerans proteasome PrcB 0.0662 0.2556 0.542
Echinococcus granulosus epidermal growth factor receptor 0.0331 0.1244 0.3315
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.013 0.0449 0.1378
Echinococcus multilocularis FTZ F1 alpha 0.029 0.1084 0.2889
Echinococcus multilocularis proteasome (prosome macropain) subunit beta type 0.013 0.0449 0.1197
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.002 0.0014 0.0043
Loa Loa (eye worm) fli-1 protein 0.0165 0.0587 0.0942
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0128 0.0404
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0045 0.0113 0.0245
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.013 0.0449 0.1421
Echinococcus granulosus tm gpcr rhodopsin 0.0964 0.3751 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0062 0.0195
Echinococcus multilocularis somatostatin receptor 0.0049 0.0128 0.034
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.002 0.0013 0.002
Loa Loa (eye worm) hypothetical protein 0.0029 0.0049 0.0078
Loa Loa (eye worm) hypothetical protein 0.0153 0.0541 0.0869
Loa Loa (eye worm) hypothetical protein 0.0049 0.0128 0.0205
Loa Loa (eye worm) hypothetical protein 0.0098 0.0322 0.0517
Entamoeba histolytica proteasome subunit alpha type 1, putative 0.013 0.0449 0.1416
Echinococcus multilocularis heat shock protein 0.0046 0.0115 0.0308
Echinococcus multilocularis G protein coupled receptor 139 0.0049 0.0128 0.034
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0045 0.0111 0.0179
Loa Loa (eye worm) proteasome subunit beta type 1 0.0515 0.1971 0.3164
Plasmodium falciparum glutathione reductase 0.0118 0.04 0.0862
Entamoeba histolytica CAAX prenyl protease, putative 0.0072 0.022 0.0692
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0045 0.0111 0.0179
Trypanosoma brucei MATE efflux family protein, putative 0.0036 0.0078 0.0125
Brugia malayi Ets-domain containing protein 0.0054 0.0149 0.0239
Trypanosoma brucei trypanothione reductase 0.0118 0.04 0.0642
Onchocerca volvulus 0.0115 0.0388 0.1456
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0049 0.0128 0.034
Loa Loa (eye worm) hypothetical protein 0.007 0.021 0.0337
Brugia malayi Cation transporter family protein 0.002 0.0013 0.002
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0056 0.0154 0.0248
Onchocerca volvulus Putative nachr subunit 0.002 0.0013 0.0045
Schistosoma mansoni proteasome catalytic subunit 1 (T01 family) 0.013 0.0449 0.1421
Loa Loa (eye worm) hypothetical protein 0.0049 0.0128 0.0205
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0267 0.0992 0.3139
Loa Loa (eye worm) SRC-1 0.0055 0.0153 0.0246
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.002 0.0013 0.002
Brugia malayi Endoplasmin precursor 0.0046 0.0115 0.0185
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0163 0.058 0.1547
Brugia malayi Nuclear hormone receptor E75 0.0137 0.0476 0.0764
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0049 0.0128 0.034
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0319 0.1196 0.3754
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.013 0.0449 0.0721
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.019 0.0209
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0041 0.0095 0.0205
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0028 0.004
Leishmania major heat shock protein 83-1 0.0046 0.0115 0.0185
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.013 0.0449 0.0721
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0178 0.064 0.1705
Trypanosoma cruzi hslVU complex proteolytic subunit, threonine peptidase, Clan T(1), family T1B 0.013 0.0449 0.0721
Brugia malayi Proteasome A-type and B-type family protein 0.013 0.0449 0.0721
Trypanosoma brucei Heat shock protein 83, putative 0.0046 0.0115 0.0185
Echinococcus multilocularis g protein coupled receptor 0.0049 0.0128 0.034
Loa Loa (eye worm) hypothetical protein 0.002 0.0013 0.002
Echinococcus granulosus tyrosine protein kinase Fyn 0.0055 0.0153 0.0409
Mycobacterium leprae Probable DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (Type II DNA topoisomerase) 0.0216 0.0791 0.2109
Loa Loa (eye worm) 20S proteasome alpha5 subunit 0.013 0.0449 0.0721
Brugia malayi beta-lactamase family protein 0.0067 0.0198 0.0318
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.002 0.0013 0.0034
Loa Loa (eye worm) hypothetical protein 0.0029 0.0049 0.0078
Schistosoma mansoni nAChR subunit 0.002 0.0013 0.004
Echinococcus granulosus sodium and chloride dependent glycine 0.0045 0.0113 0.0302
Giardia lamblia 20S proteasome alpha subunit 5 0.013 0.0449 0.1393
Schistosoma mansoni hypothetical protein 0.0049 0.0128 0.0404
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0049 0.0128 0.034
Echinococcus multilocularis g protein coupled receptor 0.0049 0.0128 0.034
Onchocerca volvulus 0.002 0.0014 0.005
Echinococcus multilocularis glycine receptor subunit alpha 1 0.002 0.0013 0.0034
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0515 0.1971 0.3164
Onchocerca volvulus 0.0094 0.0306 0.1149
Trypanosoma brucei DNA topoisomerase III, putative 0.0085 0.0271 0.0436
Trichomonas vaginalis chromobox protein, putative 0.0052 0.0141 0.0397
Echinococcus granulosus jun protein 0.0063 0.0183 0.0488
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0128 0.034
Loa Loa (eye worm) hypothetical protein 0.0067 0.0198 0.0318
Loa Loa (eye worm) hypothetical protein 0.0137 0.0476 0.0764
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0041 0.0095 0.0153
Mycobacterium ulcerans two component sensory transduction histidine kinase MtrB 0.0046 0.0115 0.0044
Echinococcus granulosus GPCR family 2 0.0029 0.005 0.0132
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.013 0.0449 0.0721
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.013 0.0449 0.0721
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0688 0.2657 0.4265
Echinococcus multilocularis NCK adaptor protein 0.002 0.0014 0.0036
Onchocerca volvulus 0.002 0.0013 0.0045
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0107 0.0355 0.0948
Trypanosoma brucei hypothetical protein, conserved 0.0067 0.0198 0.0318
Trypanosoma cruzi heat shock protein 90, putative 0.0046 0.0115 0.0185
Echinococcus granulosus proteasome subunit alpha type 6 0.013 0.0449 0.1197
Loa Loa (eye worm) hypothetical protein 0.0067 0.0198 0.0318
Echinococcus granulosus hypothetical protein 0.0812 0.3147 0.839
Echinococcus granulosus subfamily T1A non peptidase ue 0.013 0.0449 0.1197
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0045 0.0113 0.0359
Echinococcus granulosus tyrosine protein kinase Lyn 0.0062 0.0181 0.0482
Loa Loa (eye worm) hypothetical protein 0.0029 0.0049 0.0078
Brugia malayi Animal haem peroxidase family protein 0.0029 0.0049 0.0078
Loa Loa (eye worm) hypothetical protein 0.0045 0.0113 0.0182
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0137 0.0476 0.1507
Echinococcus granulosus lamin 0.002 0.0014 0.0037
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0046 0.0115 0.0317
Onchocerca volvulus 0.002 0.0013 0.0045
Mycobacterium leprae Probable DNA topoisomerase I TopA (omega-protein) (relaxing enzyme) (untwisting enzyme) (swivelase) (type I DNA topoisomerase) ( 0.0085 0.0271 0.0487
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.002 0.0013 0.0034
Entamoeba histolytica heat shock protein 90, putative 0.0046 0.0115 0.036
Loa Loa (eye worm) nuclear hormone receptor 0.0137 0.0476 0.0764
Toxoplasma gondii ABC1 family protein 0.0067 0.0198 0.0428
Mycobacterium tuberculosis Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) 0.0047 0.0119 0.0024
Brugia malayi G-protein coupled receptor 0.0049 0.0128 0.0205
Brugia malayi 20S proteasome alpha5 subunit 0.013 0.0449 0.0721
Brugia malayi G-protein coupled receptor 0.0049 0.0128 0.0205
Echinococcus multilocularis multidrug and toxin extrusion protein 2 0.0036 0.0078 0.0208
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.0161 0.0573 0.0919
Brugia malayi Cation transporter family protein 0.002 0.0013 0.002
Loa Loa (eye worm) proteasome subunit alpha type 3 0.013 0.0449 0.0721
Schistosoma mansoni biogenic amine receptor 0.0049 0.0128 0.0404
Loa Loa (eye worm) hypothetical protein 0.0049 0.0128 0.0205
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.013 0.0449 0.0721
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0043 0.0105 0.0279
Schistosoma mansoni voltage-gated potassium channel 0.0047 0.0119 0.0378
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0045 0.0113 0.0302
Loa Loa (eye worm) hypothetical protein 0.0049 0.0128 0.0205
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0045 0.0113 0.0359
Trypanosoma cruzi developmentally regulated phosphoprotein, putative 0.0046 0.0115 0.0185
Loa Loa (eye worm) TK/INSR protein kinase 0.0107 0.0355 0.0571
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0319 0.1196 0.3754
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0662 0.2556 0.8088
Loa Loa (eye worm) ICD-1 protein 0.0037 0.0081 0.0131
Echinococcus multilocularis ecdysone induced protein 78C 0.029 0.1084 0.2889
Loa Loa (eye worm) peptidase family M48 containing protein 0.0072 0.022 0.0354
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.073 0.2822 0.453
Brugia malayi Nuclear hormone receptor-like 1 0.029 0.1084 0.174
Plasmodium falciparum amino acid transporter, putative 0.0045 0.0113 0.0245
Wolbachia endosymbiont of Brugia malayi ATP-dependent protease peptidase subunit 0.013 0.0449 0.0779
Brugia malayi G protein-coupled receptor 0.0049 0.0128 0.0205
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.029 0.1084 0.343
Echinococcus multilocularis neuropeptide Y receptor 0.0049 0.0128 0.034
Chlamydia trachomatis DNA gyrase subunit B 0.0789 0.3057 0.6523
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0662 0.2556 0.4103
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0065 0.019 0.0096
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0055 0.0153 0.0409
Loa Loa (eye worm) norepinephrine transporter 0.0267 0.0992 0.1592
Leishmania major ferric reductase, putative 0.0073 0.0222 0.0356
Loa Loa (eye worm) hypothetical protein 0.0023 0.0025 0.004
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0153 0.0541 0.1443
Loa Loa (eye worm) hypothetical protein 0.0067 0.0198 0.0318
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.013 0.0449 0.1416
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0081 0.0208
Echinococcus granulosus 20S proteasome subunit alpha 6 0.013 0.0449 0.1197
Schistosoma mansoni adapter molecule crk 0.002 0.0014 0.0043
Echinococcus multilocularis heat shock protein 90 0.0046 0.0115 0.0308
Trypanosoma brucei proteasome alpha 7 subunit, putative 0.013 0.0449 0.0721
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0688 0.2657 0.4265
Brugia malayi Calcitonin receptor-like protein seb-1 0.0092 0.03 0.0481
Loa Loa (eye worm) hypothetical protein 0.0049 0.0128 0.0205
Loa Loa (eye worm) hypothetical protein 0.0046 0.0118 0.0189
Echinococcus granulosus histone acetyltransferase KAT2B 0.0045 0.0114 0.0303
Onchocerca volvulus 0.0049 0.0128 0.0478
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0049 0.0128 0.034
Echinococcus granulosus sodium and chloride dependent glycine 0.0045 0.0113 0.0302
Leishmania major heat shock protein 83-1 0.0046 0.0115 0.0185
Plasmodium falciparum DNA topoisomerase VI, b subunit, putative 0.0046 0.0115 0.0249
Onchocerca volvulus 0.0067 0.0198 0.0744
Leishmania major dihydrofolate reductase-thymidylate synthase 0.0161 0.0573 0.0919
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0371 0.1402 0.3739
Leishmania major heat shock protein 83-1 0.0046 0.0115 0.0185
Loa Loa (eye worm) T-complex protein 1 0.0027 0.004 0.0064
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0128 0.034
Brugia malayi Thioredoxin reductase 0.0118 0.04 0.0642
Schistosoma mansoni gabp alpha 0.0054 0.0149 0.0471
Onchocerca volvulus 0.0137 0.0476 0.179
Plasmodium vivax glycogen synthase kinase 3, putative 0.0688 0.2657 0.5732
Loa Loa (eye worm) intermediate filament protein 0.002 0.0014 0.0022
Brugia malayi hypothetical protein 0.0049 0.0128 0.0205
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0081 0.0208
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0092 0.03 0.0481
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0046 0.0115 0.0308
Echinococcus granulosus FTZ F1 alpha 0.029 0.1084 0.2889
Echinococcus multilocularis GPCR, family 2 0.0029 0.005 0.0132
Wolbachia endosymbiont of Brugia malayi replicative DNA helicase 0.029 0.1082 0.2172
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0041 0.0095 0.0254
Trypanosoma cruzi CAAX prenyl protease 1, putative 0.0072 0.022 0.0354
Echinococcus multilocularis serotonin receptor 0.0049 0.0128 0.034
Echinococcus multilocularis lysine specific demethylase 5A 0.0063 0.0182 0.0486
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0041 0.0095 0.0153
Schistosoma mansoni hypothetical protein 0.0314 0.1179 0.373
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0045 0.0111 0.0179
Loa Loa (eye worm) hypothetical protein 0.0153 0.0541 0.0869
Schistosoma mansoni zinc finger protein 0.0137 0.0476 0.1507
Schistosoma mansoni pyruvate dehydrogenase 0.0046 0.0115 0.0365
Brugia malayi Nuclear hormone receptor family member nhr-41 0.029 0.1084 0.174
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0078 0.0125
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0038 0.0085 0.0218
Schistosoma mansoni hypothetical protein 0.0049 0.0128 0.0404
Trypanosoma brucei heat shock protein 90, putative 0.0046 0.0115 0.0185
Trichomonas vaginalis receptor histidine kinase, putative 0.0046 0.0115 0.0317
Echinococcus multilocularis proteasome subunit beta type 7 0.013 0.0449 0.1197
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.002 0.0013 0.0034
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0055 0.0153 0.0409
Brugia malayi steroid hormone receptor 0.029 0.1084 0.174
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.029 0.1084 0.2889
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0032 0.0059 0.0218
Leishmania major DNA topoisomerase 1A 0.0085 0.0271 0.0436
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.002 0.0013 0.002
Echinococcus multilocularis lamin dm0 0.002 0.0014 0.0037
Loa Loa (eye worm) thymidylate synthase 0.0115 0.0388 0.0622
Brugia malayi Nuclear hormone receptor family member nhr-19 0.029 0.1084 0.174
Chlamydia trachomatis replicative DNA helicase 0.029 0.1082 0.2172
Loa Loa (eye worm) hypothetical protein 0.0029 0.0049 0.0078
Giardia lamblia Pms1-like protein 0.0046 0.0115 0.0258
Plasmodium falciparum proteasome subunit alpha type-7, putative 0.013 0.0449 0.0969
Echinococcus granulosus neuropeptide FF receptor 2 0.0049 0.0128 0.034
Loa Loa (eye worm) hypothetical protein 0.0111 0.0375 0.0602
Brugia malayi GYF domain containing protein 0.0074 0.0226 0.0362
Brugia malayi latrophilin 2 splice variant baaae 0.0063 0.0184 0.0295
Brugia malayi proteasome subunit beta type 2 0.0319 0.1196 0.192
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0041 0.0095 0.0153
Toxoplasma gondii proteasome subunit beta type, putative 0.0662 0.2556 0.5514
Echinococcus granulosus proteasome prosome macropain subunit beta type 0.013 0.0449 0.1197
Echinococcus granulosus epidermal growth factor receptor 0.0178 0.064 0.1705
Mycobacterium tuberculosis Conserved protein 0.0067 0.0198 0.0104
Brugia malayi Peptidase family M48 containing protein 0.0072 0.022 0.0354
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0815 0.316 0.5072
Trypanosoma brucei protein kinase, putative 0.0688 0.2657 0.4265
Brugia malayi protein-tyrosine kinase 0.0045 0.0114 0.0183
Echinococcus granulosus protein kinase shaggy 0.0688 0.2657 0.7083
Trichomonas vaginalis chromobox protein, putative 0.0032 0.0059 0.0136
Echinococcus granulosus nuclear receptor nhr 48 0.0137 0.0476 0.127
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.019 0.0209
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0094 0.0308 0.082
Loa Loa (eye worm) hypothetical protein 0.0049 0.0128 0.0205
Plasmodium vivax glutathione reductase, putative 0.0118 0.04 0.0862
Leishmania major trypanothione reductase 0.0118 0.04 0.0642
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0933 0.3629 0.5825
Toxoplasma gondii LsmAD domain-containing protein 0.0047 0.0119 0.0257
Mycobacterium leprae RECA PROTEIN (RECOMBINASE A) [CONTAINS: Mle RECA INTEIN]. 0.0081 0.0254 0.0434
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0515 0.1971 0.3164
Plasmodium vivax proteasome subunit alpha type-3, putative 0.013 0.0449 0.0969
Plasmodium vivax proteasome subunit alpha type-2, putative 0.013 0.0449 0.0969
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0049 0.0128 0.0404
Wolbachia endosymbiont of Brugia malayi DNA gyrase subunit A 0.1187 0.4636 1
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.002 0.0013 0.002
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.013 0.0449 0.1416
Mycobacterium tuberculosis Proteasome alpha subunit PrcA; assembles with beta subunit PrcB. 0.013 0.0449 0.0357
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0056 0.0154 0.0248
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.013 0.0449 0.0721
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.002 0.0013 0.002
Plasmodium falciparum thioredoxin reductase 0.0118 0.04 0.0862
Schistosoma mansoni steroid hormone receptor ad4bp 0.029 0.1084 0.343
Schistosoma mansoni Replicative DNA helicase 0.029 0.1082 0.3423
Toxoplasma gondii t-complex protein beta subunit 0.0027 0.004 0.0086
Echinococcus granulosus peptide allatostatin:somatostatin 0.0049 0.0128 0.034
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0222 0.0815 0.1308
Echinococcus granulosus rhodopsin orphan GPCR 0.0049 0.0128 0.034
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.002 0.0013 0.002
Schistosoma mansoni retinoid-x-receptor (RXR) 0.029 0.1084 0.343
Plasmodium falciparum ataxin-2 like protein, putative 0.0047 0.0119 0.0257
Schistosoma mansoni neuropeptide f receptor 76f 0.0049 0.0128 0.0404
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.029 0.1084 0.343
Plasmodium vivax proteasome subunit alpha type-1, putative 0.013 0.0449 0.0969
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0067 0.0198 0.0104
Echinococcus multilocularis sodium channel protein 0.0039 0.0089 0.0237
Schistosoma mansoni nuclear receptor 0.0137 0.0476 0.1507
Plasmodium falciparum basic transcription factor 3b, putative 0.0037 0.0081 0.0176
Loa Loa (eye worm) heterochromatin protein 1 0.0052 0.0141 0.0226
Plasmodium vivax endoplasmin, putative 0.0046 0.0115 0.0249
Brugia malayi hypothetical protein 0.0045 0.0113 0.0182
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0029 0.005 0.0132
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0045 0.0114 0.0245
Trypanosoma brucei DNA topoisomerase II beta, putative 0.073 0.2822 0.453
Loa Loa (eye worm) hypothetical protein 0.0029 0.0049 0.0078
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.013 0.0449 0.1421
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0662 0.2556 0.8079
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.002 0.0013 0.0034
Onchocerca volvulus 0.0085 0.0271 0.1019
Loa Loa (eye worm) hypothetical protein 0.0153 0.0541 0.0869
Onchocerca volvulus 0.0049 0.0128 0.0478
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.002 0.0013 0.004
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0045 0.0113 0.0359
Loa Loa (eye worm) heat shock protein 90 0.0046 0.0115 0.0185
Loa Loa (eye worm) hypothetical protein 0.0137 0.0476 0.0764
Entamoeba histolytica proteasome subunit beta Type 4 precursor, putative 0.013 0.0449 0.1416
Echinococcus multilocularis Proteasome subunit alpha type 7 0.013 0.0449 0.1197
Chlamydia trachomatis DNA gyrase subunit B 0.067 0.2588 0.549
Mycobacterium tuberculosis Probable dehydrogenase 0.0121 0.0414 0.0322
Trypanosoma brucei heat shock protein, putative 0.0046 0.0115 0.0185
Schistosoma mansoni histamine h1 receptor 0.0049 0.0128 0.0404
Chlamydia trachomatis recombinase RecA 0.0081 0.0254 0.035
Mycobacterium tuberculosis DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.1187 0.4636 0.4584
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0055 0.0153 0.0409
Plasmodium vivax proteasome subunit alpha type-5, putative 0.013 0.0449 0.0969
Schistosoma mansoni tyrosine kinase 0.0023 0.0026 0.0081
Loa Loa (eye worm) solute carrier family 6 member 4 0.0267 0.0992 0.1592
Schistosoma mansoni hypothetical protein 0.0051 0.0136 0.0432
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0151 0.0532 0.1302
Brugia malayi hypothetical protein 0.0049 0.0128 0.0205
Mycobacterium tuberculosis Conserved protein 0.0067 0.0198 0.0104
Giardia lamblia Proteasome subunit beta type 4 precursor 0.013 0.0449 0.1393
Mycobacterium ulcerans DNA gyrase subunit A 0.1187 0.4636 1
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.013 0.0449 0.0721
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0371 0.1402 0.2251
Trypanosoma cruzi trypanothione reductase, putative 0.0118 0.04 0.0642
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0067 0.0198 0.0227
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0029 0.005 0.0132
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0137 0.0476 0.0764
Entamoeba histolytica proteasome subunit alpha type 2-A, putative 0.013 0.0449 0.1416
Brugia malayi AKH receptor 0.0049 0.0128 0.0205
Toxoplasma gondii CAAX metallo endopeptidase 0.0072 0.022 0.0475
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0041 0.0095 0.0205
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.002 0.0013 0.0034
Mycobacterium ulcerans beta-lactamase 0.0067 0.0198 0.0227
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0789 0.3057 0.6523
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0021 0.0017 0.0045
Brugia malayi nuclear receptor NHR-67 0.0137 0.0476 0.0764
Schistosoma mansoni lamin 0.002 0.0014 0.0044
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0041 0.0096 0.0302
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0049 0.0128 0.0404
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0662 0.2556 0.8563
Wolbachia endosymbiont of Brugia malayi membrane associated signal transduction histidine kinase 0.0046 0.0115 0.0044
Brugia malayi kinase, mitochondrial precursor 0.0046 0.0115 0.0185
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0056 0.0154 0.0412
Echinococcus multilocularis Proteasome subunit alpha type 7 0.013 0.0449 0.1197
Echinococcus multilocularis lamin 0.002 0.0014 0.0037
Trypanosoma brucei membrane transporter protein, putative 0.0036 0.0078 0.0125
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0163 0.058 0.1836
Giardia lamblia Kinase, CMGC MAPK 0.0045 0.0111 0.0243
Schistosoma mansoni hypothetical protein 0.0049 0.0128 0.0404
Schistosoma mansoni nuclear hormone receptor 0.0137 0.0476 0.1507
Plasmodium vivax heat shock protein 86, putative 0.0046 0.0115 0.0249
Toxoplasma gondii heat shock protein hslv, putative 0.013 0.0449 0.0969
Brugia malayi ERG2 and Sigma1 receptor like protein 0.159 0.6231 1
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.0161 0.0573 0.1235
Echinococcus granulosus rhodopsin orphan GPCR 0.0049 0.0128 0.034
Onchocerca volvulus 0.0049 0.0128 0.0478
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0041 0.0095 0.0153
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0067 0.0198 0.0627
Treponema pallidum DNA gyrase, subunit A (gyrA) 0.1187 0.4636 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0064 0.0187 0.03
Echinococcus granulosus retinoic acid receptor rxr beta a 0.029 0.1084 0.2889
Loa Loa (eye worm) hypothetical protein 0.0137 0.0476 0.0764
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0128 0.0404
Loa Loa (eye worm) hypothetical protein 0.0049 0.0128 0.0205
Loa Loa (eye worm) thioredoxin reductase 0.0118 0.04 0.0642
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0049 0.0128 0.034
Loa Loa (eye worm) hypothetical protein 0.0137 0.0476 0.0764
Trypanosoma cruzi proteasome beta 2 subunit, putative 0.013 0.0449 0.0721
Loa Loa (eye worm) hypothetical protein 0.0153 0.0541 0.0869
Echinococcus multilocularis Proteasome subunit alpha type 7 0.013 0.0449 0.1197
Echinococcus multilocularis transcription factor btf3 0.0037 0.0081 0.0217
Loa Loa (eye worm) melatonin receptor type 1A 0.0049 0.0128 0.0205
Giardia lamblia Proteasome subunit beta type 1 0.0515 0.1971 0.6573
Toxoplasma gondii proteasome subunit alpha type, putative 0.013 0.0449 0.0969
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0049 0.0128 0.034
Loa Loa (eye worm) hypothetical protein 0.0049 0.0128 0.0205
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.029 0.1084 0.2889
Loa Loa (eye worm) hypothetical protein 0.002 0.0013 0.002
Plasmodium vivax ATP-dependent protease subunit ClpQ, putative 0.013 0.0449 0.0969
Entamoeba histolytica protein kinase, putative 0.0688 0.2657 0.8408
Trypanosoma brucei DNA topoisomerase III, putative 0.0085 0.0271 0.0436
Echinococcus granulosus biogenic amine 5HT receptor 0.0049 0.0128 0.034
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0065 0.0192 0.0609
Brugia malayi Latrophilin receptor protein 2 0.0029 0.005 0.008
Onchocerca volvulus 0.029 0.1084 0.4077
Trichomonas vaginalis set domain proteins, putative 0.0253 0.0936 0.2927
Echinococcus multilocularis glycine receptor subunit alpha 1 0.002 0.0013 0.0034
Schistosoma mansoni DNA topoisomerase II 0.0815 0.316 1
Toxoplasma gondii NADPH-glutathione reductase 0.0041 0.0095 0.0205
Brugia malayi Peroxidasin 0.0029 0.0049 0.0078
Wolbachia endosymbiont of Brugia malayi topoisomerase IA, TopA 0.0085 0.0271 0.0388
Mycobacterium ulcerans two component sensor histidine kinase SenX3 0.0046 0.0115 0.0044
Trypanosoma brucei transcription factor BTF3, putative 0.0037 0.0081 0.0131
Toxoplasma gondii proteasome beta subunit 0.013 0.0449 0.0969
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0067 0.0198 0.0318
Plasmodium vivax proteasome subunit alpha type-7, putative 0.013 0.0449 0.0969
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0056 0.0154 0.0333
Mycobacterium ulcerans two component system response phosphate sensor kinase, PhoR 0.0046 0.0115 0.0044
Echinococcus granulosus nuclear receptor 2DBD gamma 0.029 0.1084 0.2889
Brugia malayi beta-lactamase 0.0067 0.0198 0.0318
Trypanosoma brucei DNA topoisomerase ii 0.0933 0.3629 0.5825
Treponema pallidum DNA topoisomerase I (topA) 0.0085 0.0271 0.0553
Echinococcus multilocularis chromobox protein 1 0.0052 0.0141 0.0375
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.013 0.0449 0.0721
Schistosoma mansoni coup transcription factor 0.029 0.1084 0.343
Schistosoma mansoni dihydrofolate reductase 0.0047 0.0119 0.0376
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0688 0.2657 0.7083
Toxoplasma gondii peptidase, T1 family protein 0.013 0.0449 0.0969
Brugia malayi Dihydrofolate reductase 0.0047 0.0119 0.0191
Brugia malayi hypothetical protein 0.0029 0.0049 0.0078
Echinococcus granulosus tm gpcr rhodopsin 0.0049 0.0128 0.034
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0028 0.004
Echinococcus multilocularis cpg binding protein 0.0023 0.0024 0.0064
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0151 0.0532 0.0441
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.002 0.0013 0.0034
Brugia malayi Protein kinase domain containing protein 0.0107 0.0355 0.0571
Onchocerca volvulus 0.0045 0.0113 0.0424
Schistosoma mansoni retinoic acid receptor RXR 0.029 0.1084 0.343
Plasmodium vivax amine transporter, putative 0.0045 0.0113 0.0245
Plasmodium vivax proteasome subunit beta type-7, putative 0.013 0.0449 0.0969
Loa Loa (eye worm) hypothetical protein 0.002 0.0013 0.002
Schistosoma mansoni amine GPCR 0.0049 0.0128 0.0404
Loa Loa (eye worm) hypothetical protein 0.0049 0.0128 0.0205
Brugia malayi GRF zinc finger family protein 0.0085 0.0271 0.0436
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0029 0.005 0.0132
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.029 0.1084 0.2889
Plasmodium falciparum proteasome subunit alpha type-6, putative 0.013 0.0449 0.0969
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.002 0.0013 0.004
Brugia malayi Nuclear hormone receptor E75 0.0137 0.0476 0.0764
Trichomonas vaginalis Clan MA, family M48, Ste24 endopeptidase-like metallopeptidase 0.0072 0.022 0.065
Echinococcus granulosus neuropeptide receptor 0.0049 0.0128 0.034
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0045 0.0113 0.0245
Loa Loa (eye worm) PAS-3 protein 0.013 0.0449 0.0721
Echinococcus multilocularis fmrfamide receptor 0.0049 0.0128 0.034
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0045 0.0113 0.0359
Loa Loa (eye worm) hypothetical protein 0.0101 0.0332 0.0533
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0045 0.0113 0.0359
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0042 0.0102 0.0271
Loa Loa (eye worm) hypothetical protein 0.0098 0.0322 0.0517
Brugia malayi Trypsin family protein 0.0101 0.0332 0.0533
Plasmodium vivax DNA gyrase subunit B, putative 0.0789 0.3057 0.6594
Trichomonas vaginalis CMGC family protein kinase 0.0688 0.2657 0.8401
Echinococcus multilocularis thioredoxin glutathione reductase 0.0118 0.04 0.1066
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.002 0.0013 0.002
Entamoeba histolytica DNA topoisomerase III, putative 0.0085 0.0271 0.0854
Plasmodium falciparum proteasome subunit beta type-5 0.0662 0.2556 0.5514
Toxoplasma gondii DNA gyrase/topoisomerase IV, A subunit domain-containing protein 0.1187 0.4636 1
Schistosoma mansoni intermediate filament proteins 0.002 0.0014 0.0044
Loa Loa (eye worm) twinkle helicase 0.0083 0.0262 0.042
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0027 0.004 0.0126
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0029 0.005 0.0132
Brugia malayi intracellular kinase 0.0688 0.2657 0.4265

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 0.007 uM Inhibitory concentration of the compound against Growth factor receptor bound protein 2 in MDA-MB-453 cells ChEMBL. 10091682
IC50 (binding) = 0.007 uM Inhibitory concentration of the compound against Growth factor receptor bound protein 2 in MDA-MB-453 cells ChEMBL. 10091682

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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