Detailed information for compound 205980

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 386.325 | Formula: C21H24BrNO
  • H donors: 0 H acceptors: 0 LogP: 5.17 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: Brc1cccc(c1)C(c1ccccc1)OC1CC2CCC(C1)N2C
  • InChi: 1S/C21H24BrNO/c1-23-18-10-11-19(23)14-20(13-18)24-21(15-6-3-2-4-7-15)16-8-5-9-17(22)12-16/h2-9,12,18-21H,10-11,13-14H2,1H3
  • InChiKey: MQTSMELUXUVGJV-UHFFFAOYSA-N  


Substructure search Similarity search

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0419 0.5655 0.895
Echinococcus granulosus tyrosine protein kinase csk 0.0348 0.4646 0.4645
Trichomonas vaginalis chromobox protein, putative 0.0032 0.0197 0.032
Loa Loa (eye worm) PHD-finger family protein 0.0056 0.0535 0.0849
Loa Loa (eye worm) TK/EGFR protein kinase 0.0348 0.4646 0.7407
Schistosoma mansoni slit 0.004 0.03 0.03
Leishmania major hypothetical protein, conserved 0.004 0.03 0.0364
Schistosoma mansoni sex comb on midleg homolog 0.0084 0.092 0.092
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0028 0.0138 0.0135
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0348 0.4646 0.7407
Schistosoma mansoni tyrosine kinase 0.0348 0.4646 0.4646
Trichomonas vaginalis AGC family protein kinase 0.0348 0.4646 0.8678
Plasmodium falciparum protein kinase, putative 0.0348 0.4646 1
Brugia malayi Glycosyl hydrolases family 31 protein 0.0146 0.18 0.287
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0028 0.0138 0.0135
Loa Loa (eye worm) hypothetical protein 0.0084 0.092 0.1464
Schistosoma mansoni tyrosine kinase 0.0348 0.4646 0.4646
Schistosoma mansoni leucine-rich repeat protein 0.004 0.03 0.03
Echinococcus multilocularis tyrosine protein kinase csk 0.0348 0.4646 0.4645
Trichomonas vaginalis D-aminoacylase, putative 0.0063 0.0628 0.113
Plasmodium falciparum cysteine repeat modular protein 1 0.0115 0.1366 0.2936
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0348 0.4646 0.7408
Entamoeba histolytica leucine rich repeat / protein phosphatase 2C domain containing protein 0.004 0.03 0.0527
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0051 0.0461 0.0461
Trichomonas vaginalis CAMK family protein kinase 0.0348 0.4646 0.8678
Entamoeba histolytica leucine rich repeat and phosphatase domain containing protein 0.004 0.03 0.0527
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0348 0.4646 0.4646
Echinococcus multilocularis peregrin 0.0056 0.0535 0.0532
Echinococcus granulosus tyrosine protein kinase csk 0.0348 0.4646 0.4645
Trichomonas vaginalis penicillin-binding protein, putative 0.0063 0.0628 0.113
Trichomonas vaginalis TKL family protein kinase 0.0348 0.4646 0.8678
Entamoeba histolytica protein kinase, putative 0.0348 0.4646 0.892
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0078 0.0835 0.1078
Brugia malayi jmjC domain containing protein 0.0124 0.1493 0.238
Entamoeba histolytica protein kinase, putative 0.0348 0.4646 0.892
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0348 0.4646 0.8678
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0147 0.1819 1
Brugia malayi latrophilin 2 splice variant baaae 0.0061 0.0599 0.0954
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0028 0.0142 0.0153
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0097 0.1103 0.1711
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0348 0.4646 0.892
Onchocerca volvulus 0.0348 0.4646 0.8684
Loa Loa (eye worm) hypothetical protein 0.004 0.03 0.0474
Entamoeba histolytica leucine rich repeat / protein phosphatase 2C domain containing protein 0.004 0.03 0.0527
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0348 0.4646 0.4645
Brugia malayi Pre-SET motif family protein 0.035 0.4671 0.7448
Giardia lamblia Hypothetical protein 0.004 0.03 0.0591
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0035 0.0238 0.0235
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0348 0.4646 0.7407
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0064 0.0639 0.137
Trichomonas vaginalis leucine-rich repeat-containing protein, putative 0.004 0.03 0.0513
Onchocerca volvulus 0.0348 0.4646 0.8684
Schistosoma mansoni hypothetical protein 0.0028 0.0138 0.0138
Plasmodium vivax tyrosine kinase-like protein, putative 0.0348 0.4646 1
Schistosoma mansoni chromobox protein 0.0054 0.0497 0.0497
Brugia malayi Leucine Rich Repeat family protein 0.004 0.03 0.0478
Entamoeba histolytica hypothetical protein 0.0348 0.4646 0.892
Trypanosoma cruzi trypanothione reductase, putative 0.0064 0.0639 0.0816
Echinococcus multilocularis leucine rich repeat containing protein 40 0.004 0.03 0.0297
Echinococcus multilocularis tyrosine protein kinase csk 0.0348 0.4646 0.4645
Entamoeba histolytica leucine rich repeat / protein phosphatase 2C domain containing protein 0.004 0.03 0.0527
Giardia lamblia Protein 21.1 0.0348 0.4646 1
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0348 0.4646 0.4645
Brugia malayi Protein kinase domain containing protein 0.0348 0.4646 0.7408
Entamoeba histolytica villidin, putative 0.004 0.03 0.0527
Entamoeba histolytica protein kinase domain containing protein 0.0348 0.4646 0.892
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.03 0.0364
Schistosoma mansoni transcription factor LCR-F1 0.0066 0.0665 0.0665
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0348 0.4646 0.4645
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0334 0.4449 0.4447
Echinococcus multilocularis beta LACTamase domain containing family member 0.0063 0.0628 0.0626
Onchocerca volvulus 0.0115 0.1366 0.2549
Echinococcus multilocularis activin receptor type 0.0348 0.4646 0.4645
Trypanosoma cruzi Calcium/calmodulin-dependent protein kinase kinase, putative 0.004 0.03 0.0364
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0064 0.0639 0.0848
Echinococcus multilocularis tyrosine protein kinase Abl 0.0348 0.4646 0.4645
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0019 0.0003 0.0003
Brugia malayi mbt repeat family protein 0.0084 0.092 0.1468
Trichomonas vaginalis TKL family protein kinase 0.0348 0.4646 0.8678
Schistosoma mansoni ap endonuclease 0.002 0.0027 0.0027
Schistosoma mansoni hypothetical protein 0.004 0.03 0.03
Echinococcus multilocularis tyrosine kinase 0.0348 0.4646 0.4645
Trichomonas vaginalis leucine-rich transmembrane proteins, putative 0.004 0.03 0.0513
Echinococcus granulosus c src tyrosine kinase 0.0348 0.4646 0.4645
Trichomonas vaginalis TKL family protein kinase 0.0348 0.4646 0.8678
Plasmodium vivax ataxin-2 like protein, putative 0.0023 0.0059 0.0122
Entamoeba histolytica protein kinase, putative 0.0348 0.4646 0.892
Plasmodium vivax tyrosine kinase-like protein, putative 0.0348 0.4646 1
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0105 0.122 0.122
Echinococcus multilocularis epidermal growth factor receptor 0.0348 0.4646 0.4645
Brugia malayi Leucine Rich Repeat family protein 0.004 0.03 0.0478
Echinococcus granulosus tyrosine protein kinase HCK 0.0348 0.4646 0.4645
Brugia malayi beta-lactamase 0.0063 0.0628 0.1002
Echinococcus multilocularis leucine rich repeat 0.004 0.03 0.0297
Brugia malayi Immunoglobulin I-set domain containing protein 0.0348 0.4646 0.7408
Brugia malayi PDZ-domain protein scribble 0.004 0.03 0.0478
Trichomonas vaginalis protein kinase atn1, putative 0.0348 0.4646 0.8678
Entamoeba histolytica protein kinase domain containing protein 0.0348 0.4646 0.892
Echinococcus granulosus inositol monophosphatase 1 0.0028 0.0142 0.0139
Loa Loa (eye worm) leucine Rich Repeat family protein 0.004 0.03 0.0474
Echinococcus multilocularis protein kinase 0.0348 0.4646 0.4645
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0225 0.2916 0.5428
Loa Loa (eye worm) TK/FER protein kinase 0.0348 0.4646 0.7407
Schistosoma mansoni survival motor neuron protein 0.0085 0.0935 0.0935
Echinococcus multilocularis dnaJ subfamily B 0.0727 1 1
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0063 0.0628 0.0998
Onchocerca volvulus 0.004 0.03 0.0556
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0334 0.4449 0.4447
Trypanosoma cruzi Calcium/calmodulin-dependent protein kinase kinase, putative 0.004 0.03 0.0364
Trichomonas vaginalis conserved hypothetical protein 0.0348 0.4646 0.8678
Trichomonas vaginalis leucine-rich transmembrane protein, putative 0.004 0.03 0.0513
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0028 0.0138 0.0135
Brugia malayi Protein kinase domain containing protein 0.0348 0.4646 0.7408
Brugia malayi glutathione reductase 0.0184 0.2333 0.372
Echinococcus granulosus tyrosine protein kinase 0.0348 0.4646 0.4645
Brugia malayi SRC-1 0.0348 0.4646 0.7408
Onchocerca volvulus 0.0348 0.4646 0.8684
Mycobacterium ulcerans hypothetical protein 0.0291 0.3843 1
Trypanosoma brucei kinatase, putative 0.004 0.03 0.0398
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0051 0.0456 0.0978
Echinococcus granulosus receptor type guanylyl cyclase 0.0348 0.4646 0.4645
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0051 0.0461 0.0461
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0348 0.4646 0.892
Loa Loa (eye worm) TK/FER protein kinase 0.0348 0.4646 0.7407
Brugia malayi SH2 domain containing protein 0.0348 0.4646 0.7408
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0078 0.0835 0.1078
Schistosoma mansoni tyrosine kinase 0.0348 0.4646 0.4646
Loa Loa (eye worm) leucine Rich Repeat family protein 0.004 0.03 0.0474
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0348 0.4646 0.4645
Entamoeba histolytica protein kinase, putative 0.0348 0.4646 0.892
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0348 0.4646 0.7408
Loa Loa (eye worm) hypothetical protein 0.0348 0.4646 0.7407
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0027 0.0001
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0022 0.0044 0.0089
Plasmodium falciparum ataxin-2 like protein, putative 0.0023 0.0059 0.0122
Schistosoma mansoni protein kinase 0.0348 0.4646 0.4646
Onchocerca volvulus 0.0348 0.4646 0.8684
Loa Loa (eye worm) hypothetical protein 0.0063 0.0628 0.0998
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0051 0.0461 0.0459
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0064 0.0639 0.1604
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0064 0.0639 0.0816
Trichomonas vaginalis TKL family protein kinase 0.0348 0.4646 0.8678
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0064 0.0639 0.0816
Echinococcus multilocularis tyrosine protein kinase HCK 0.0348 0.4646 0.4645
Echinococcus multilocularis geminin 0.0551 0.7508 0.7507
Schistosoma mansoni alpha-glucosidase 0.0126 0.1513 0.1513
Echinococcus multilocularis GPCR, family 2 0.0028 0.0138 0.0135
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0019 0.0003 0.0003
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0348 0.4646 0.4645
Loa Loa (eye worm) hypothetical protein 0.0111 0.1302 0.2073
Entamoeba histolytica protein kinase domain containing protein 0.0348 0.4646 0.892
Trichomonas vaginalis conserved hypothetical protein 0.004 0.03 0.0513
Echinococcus granulosus protein tyrosine kinase 0.0348 0.4646 0.4645
Entamoeba histolytica protein kinase, putative 0.0348 0.4646 0.892
Echinococcus granulosus retinal guanylyl cyclase 2 0.0348 0.4646 0.4645
Trichomonas vaginalis TKL family protein kinase 0.0348 0.4646 0.8678
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0225 0.2916 0.5428
Loa Loa (eye worm) transcription factor SMAD2 0.0099 0.1144 0.182
Schistosoma mansoni tyrosine kinase 0.0348 0.4646 0.4646
Brugia malayi Protein kinase domain containing protein 0.0348 0.4646 0.7408
Plasmodium vivax hypothetical protein, conserved 0.0056 0.0535 0.1146
Brugia malayi Inositol-1 0.0028 0.0142 0.0226
Trypanosoma cruzi phopshatase, putative 0.004 0.03 0.0364
Echinococcus multilocularis Leucine rich repeat domain containing protein 0.004 0.03 0.0297
Entamoeba histolytica protein kinase domain containing protein 0.0348 0.4646 0.892
Schistosoma mansoni tyrosine kinase 0.0348 0.4646 0.4646
Entamoeba histolytica leucine rich repeat / protein phosphatase 2C domain containing protein 0.004 0.03 0.0527
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0348 0.4646 0.4646
Trichomonas vaginalis alpha-glucosidase, putative 0.0032 0.0197 0.0321
Loa Loa (eye worm) hypothetical protein 0.0348 0.4646 0.7407
Loa Loa (eye worm) TK/FER protein kinase 0.0348 0.4646 0.7407
Schistosoma mansoni tyrosine kinase 0.0348 0.4646 0.4646
Schistosoma mansoni tyrosine kinase 0.0348 0.4646 0.4646
Loa Loa (eye worm) leucine Rich Repeat family protein 0.004 0.03 0.0474
Loa Loa (eye worm) TK/FER protein kinase 0.0348 0.4646 0.7407
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0084 0.092 0.092
Schistosoma mansoni tyrosine kinase 0.0348 0.4646 0.4646
Brugia malayi hypothetical protein 0.0348 0.4646 0.7408
Loa Loa (eye worm) hypothetical protein 0.0063 0.0628 0.0998
Trypanosoma brucei phosphatase, putative 0.004 0.03 0.0398
Loa Loa (eye worm) TK/FER protein kinase 0.0348 0.4646 0.7407
Trypanosoma cruzi hypothetical protein, conserved 0.0063 0.0628 0.0802
Schistosoma mansoni hypothetical protein 0.0513 0.6972 0.6972
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0466 0.6315 1
Schistosoma mansoni sex comb on midleg homolog 0.0084 0.092 0.092
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0019 0.0003 0.0005
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0348 0.4646 0.4645
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0552 0.7529 1
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0063 0.0628 0.0957
Brugia malayi Protein kinase domain containing protein 0.0348 0.4646 0.7408
Echinococcus granulosus tyrosine protein kinase shark 0.0348 0.4646 0.4645
Trichomonas vaginalis inositol monophosphatase, putative 0.0028 0.0142 0.0216
Leishmania major hypothetical protein, conserved 0.0348 0.4646 0.6157
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0348 0.4646 0.7408
Trypanosoma brucei paraflagellar rod component, putative 0.004 0.03 0.0398
Loa Loa (eye worm) TK/DDR protein kinase 0.0348 0.4646 0.7407
Schistosoma mansoni tyrosine kinase 0.0348 0.4646 0.4646
Plasmodium vivax protein kinase, putative 0.0348 0.4646 1
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0147 0.1819 0.1817
Brugia malayi Protein kinase domain containing protein 0.0348 0.4646 0.7408
Entamoeba histolytica serine/threonine kinase, putative 0.0348 0.4646 0.892
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0147 0.1819 0.1817
Trichomonas vaginalis alpha-glucosidase, putative 0.0032 0.0197 0.0321
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.03 0.0364
Schistosoma mansoni aldehyde dehydrogenase 0.0053 0.0491 0.0491
Onchocerca volvulus 0.0063 0.0628 0.117
Trichomonas vaginalis TKL family protein kinase 0.0348 0.4646 0.8678
Entamoeba histolytica tyrosine kinase, putative 0.0348 0.4646 0.892
Loa Loa (eye worm) hypothetical protein 0.0089 0.0996 0.1585
Schistosoma mansoni protein kinase 0.0348 0.4646 0.4646
Entamoeba histolytica protein kinase, putative 0.0348 0.4646 0.892
Brugia malayi Calcitonin receptor-like protein seb-1 0.0089 0.0996 0.1588
Entamoeba histolytica protein kinase domain containing protein 0.0348 0.4646 0.892
Echinococcus multilocularis tyrosine protein kinase shark 0.0348 0.4646 0.4645
Schistosoma mansoni hypothetical protein 0.0727 1 1
Echinococcus granulosus retinal guanylyl cyclase 2 0.0348 0.4646 0.4645
Trichomonas vaginalis TKL family protein kinase 0.0348 0.4646 0.8678
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0333 0.4442 0.4442
Brugia malayi Immunoglobulin I-set domain containing protein 0.004 0.03 0.0478
Entamoeba histolytica protein kinase, putative 0.0348 0.4646 0.892
Entamoeba histolytica tyrosine kinase, putative 0.0348 0.4646 0.892
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0064 0.0639 0.0816
Echinococcus granulosus leucine rich repeat protein soc 2 0.004 0.03 0.0297
Loa Loa (eye worm) hypothetical protein 0.004 0.03 0.0474
Schistosoma mansoni tyrosine kinase 0.0348 0.4646 0.4646
Loa Loa (eye worm) RGC/RGC protein kinase 0.0348 0.4646 0.7407
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0348 0.4646 0.7407
Loa Loa (eye worm) hypothetical protein 0.0415 0.5597 0.8923
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0348 0.4646 0.4645
Schistosoma mansoni hypothetical protein 0.0115 0.1366 0.1366
Echinococcus granulosus protein phosphatase 1 regulatory subunit 7 0.004 0.03 0.0297
Trichomonas vaginalis protein phosphatase 2C, putative 0.004 0.03 0.0513
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0348 0.4646 0.7407
Entamoeba histolytica hypothetical protein 0.0387 0.5206 1
Loa Loa (eye worm) TK protein kinase 0.0348 0.4646 0.7407
Brugia malayi Leucine Rich Repeat family protein 0.004 0.03 0.0478
Schistosoma mansoni ras suppressor protein 1 rsu1 0.004 0.03 0.03
Echinococcus multilocularis JmjC domain containing protein 4 0.0032 0.0197 0.0194
Schistosoma mansoni serine/threonine RGC 0.0348 0.4646 0.4646
Leishmania major hypothetical protein, conserved 0.0115 0.1366 0.1785
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0027 0.0024
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0348 0.4646 0.8678
Brugia malayi Raf kinase 0.0348 0.4646 0.7408
Trichomonas vaginalis TKL family protein kinase 0.0348 0.4646 0.8678
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0105 0.122 0.1218
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0105 0.122 0.3127
Brugia malayi Leucine Rich Repeat family protein 0.004 0.03 0.0478
Loa Loa (eye worm) TKL/LRRK protein kinase 0.004 0.03 0.0474
Entamoeba histolytica leucine-rich repeat containing protein 0.004 0.03 0.0527
Trypanosoma cruzi kinatase, putative 0.004 0.03 0.0364
Toxoplasma gondii protein kinase domain-containing protein 0.0348 0.4646 1
Echinococcus multilocularis leucine rich repeat and death domain containing protein 0.004 0.03 0.0297
Loa Loa (eye worm) leucine Rich Repeat family protein 0.004 0.03 0.0474
Loa Loa (eye worm) RGC/RGC protein kinase 0.0348 0.4646 0.7407
Toxoplasma gondii PHD-finger domain-containing protein 0.0056 0.0535 0.1151
Schistosoma mansoni peptidase Clp (S14 family) 0.0147 0.1819 0.1819
Toxoplasma gondii hypothetical protein 0.0019 0.0003 0.0005
Onchocerca volvulus 0.0348 0.4646 0.8684
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0053 0.0491 0.0738
Trichomonas vaginalis TKL family protein kinase 0.0348 0.4646 0.8678
Giardia lamblia Fructose-bisphosphate aldolase 0.0225 0.2916 0.6255
Toxoplasma gondii ABC1 family protein 0.0063 0.0628 0.1353
Loa Loa (eye worm) hypothetical protein 0.0032 0.0197 0.031
Echinococcus granulosus raf serine:threonine protein kinase 0.0348 0.4646 0.4645
Echinococcus granulosus ephrin type A receptor 4 A 0.0348 0.4646 0.4645
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0348 0.4646 0.4645
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0348 0.4646 0.4645
Entamoeba histolytica tyrosin kinase, putative 0.0348 0.4646 0.892
Echinococcus granulosus leucine rich repeats and immunoglobulin 0.004 0.03 0.0297
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0032 0.0197 0.0311
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0147 0.1819 0.2766
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0147 0.1819 0.3915
Echinococcus multilocularis leucine rich repeat serine:threonine protein 0.004 0.03 0.0297
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0348 0.4646 0.4645
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0348 0.4646 0.6171
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0027 0.0001
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0032 0.0197 0.0423
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0348 0.4646 0.892
Trichomonas vaginalis protein tyrosine kinase, putative 0.0348 0.4646 0.8678
Entamoeba histolytica leucine-rich repeat containing protein 0.004 0.03 0.0527
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0466 0.6315 1
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0348 0.4646 0.7407
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0147 0.1819 0.3915
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0147 0.1819 0.4696
Schistosoma mansoni tyrosine kinase 0.0348 0.4646 0.4646
Echinococcus multilocularis slit 1 protein 0.004 0.03 0.0297
Brugia malayi ras suppressor protein 1 0.004 0.03 0.0478
Entamoeba histolytica hypothetical protein 0.0348 0.4646 0.892
Onchocerca volvulus Slit protein homolog 0.004 0.03 0.0556
Entamoeba histolytica leucine-rich repeat containing protein 0.004 0.03 0.0527
Trichomonas vaginalis TKL family protein kinase 0.0348 0.4646 0.8678
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.011 0.1292 0.3315
Onchocerca volvulus 0.004 0.03 0.0556
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0348 0.4646 0.7408
Entamoeba histolytica protein kinase domain containing protein 0.0348 0.4646 0.892
Entamoeba histolytica tyrosine kinase, putative 0.0348 0.4646 0.892
Echinococcus multilocularis natriuretic peptide receptor 1 0.0348 0.4646 0.4645
Loa Loa (eye worm) hypothetical protein 0.004 0.03 0.0474
Brugia malayi Peroxidasin 0.004 0.03 0.0478
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0053 0.0491 0.0618
Loa Loa (eye worm) thioredoxin reductase 0.0184 0.2333 0.3717
Schistosoma mansoni tyrosine kinase 0.0348 0.4646 0.4646
Brugia malayi F/Y-rich N-terminus family protein 0.0036 0.0246 0.0392
Entamoeba histolytica protein kinase, putative 0.0348 0.4646 0.892
Schistosoma mansoni hypothetical protein 0.0061 0.0599 0.0599
Entamoeba histolytica hypothetical protein 0.0066 0.0665 0.1233
Brugia malayi Protein kinase domain containing protein 0.0348 0.4646 0.7408
Trichomonas vaginalis leucine-rich repeat protein, BspA family 0.004 0.03 0.0513
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0044 0.0358 0.0622
Entamoeba histolytica serine/threonine kinase, putative 0.0348 0.4646 0.892
Trypanosoma brucei hypothetical protein, conserved 0.0063 0.0628 0.0835
Plasmodium falciparum protein kinase, putative 0.0348 0.4646 1
Brugia malayi Protein kinase domain containing protein 0.0348 0.4646 0.7408
Trichomonas vaginalis TKL family protein kinase 0.0348 0.4646 0.8678
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0064 0.0639 0.1375
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0348 0.4646 0.4645
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0348 0.4646 0.4645
Echinococcus granulosus thioredoxin glutathione reductase 0.0184 0.2339 0.2337
Brugia malayi Tyrosine-protein kinase abl-1 0.0348 0.4646 0.7408
Entamoeba histolytica protein kinase domain containing protein 0.0348 0.4646 0.892
Echinococcus granulosus Leucine rich repeat domain containing protein 0.004 0.03 0.0297
Entamoeba histolytica serine/threonine kinase, putative 0.0348 0.4646 0.892
Trichomonas vaginalis TKL family protein kinase 0.0348 0.4646 0.8678
Echinococcus multilocularis thioredoxin glutathione reductase 0.0184 0.2339 0.2337
Loa Loa (eye worm) leucine Rich Repeat family protein 0.004 0.03 0.0474
Loa Loa (eye worm) hypothetical protein 0.004 0.03 0.0474
Brugia malayi Leucine Rich Repeat family protein 0.004 0.03 0.0478
Entamoeba histolytica receptor protein kinase, putative 0.0348 0.4646 0.892
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0027 0.0001
Echinococcus multilocularis receptor type guanylyl cyclase 0.0348 0.4646 0.4645
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0333 0.4442 0.4441
Entamoeba histolytica tyrosine kinase, putative 0.0348 0.4646 0.892
Schistosoma mansoni tyrosine kinase 0.0348 0.4646 0.4646
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0348 0.4646 0.4645
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0348 0.4646 0.4645
Trypanosoma cruzi PAB1-binding protein , putative 0.0023 0.0059 0.0043
Brugia malayi Leucine Rich Repeat family protein 0.004 0.03 0.0478
Brugia malayi Protein kinase domain containing protein 0.0348 0.4646 0.7408
Schistosoma mansoni aldehyde dehydrogenase 0.0053 0.0491 0.0491
Echinococcus multilocularis leucine rich repeat containing protein 23 0.004 0.03 0.0297
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0019 0.0003 0.0003
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.004 0.03 0.0474
Mycobacterium ulcerans aldehyde dehydrogenase 0.0053 0.0491 0.1216
Leishmania major alpha glucosidase II subunit, putative 0.0032 0.0197 0.0228
Schistosoma mansoni protein kinase 0.0348 0.4646 0.4646
Trichomonas vaginalis leucine-rich transmembrane proteins, putative 0.004 0.03 0.0513
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0333 0.4442 0.4441
Entamoeba histolytica hypothetical protein 0.0348 0.4646 0.892
Echinococcus multilocularis tyrosine protein kinase 0.0348 0.4646 0.4645
Trypanosoma brucei glucosidase, putative 0.0032 0.0197 0.0262
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0097 0.1103 0.1711
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0085 0.0935 0.1491
Trypanosoma cruzi hypothetical protein, conserved 0.0032 0.0197 0.0228
Entamoeba histolytica tyrosine kinase, putative 0.0348 0.4646 0.892
Schistosoma mansoni hypothetical protein 0.0028 0.0138 0.0138
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0066 0.0665 0.0663
Schistosoma mansoni hypothetical protein 0.004 0.03 0.03
Plasmodium vivax conserved Plasmodium protein, unknown function 0.004 0.03 0.064
Brugia malayi ephrin receptor 1 precursor 0.0348 0.4646 0.7408
Trichomonas vaginalis leucine-rich transmembrane protein, putative 0.004 0.03 0.0513
Trichomonas vaginalis TKL family protein kinase 0.0348 0.4646 0.8678
Onchocerca volvulus 0.0348 0.4646 0.8684
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0348 0.4646 0.6157
Schistosoma mansoni protein kinase 0.0348 0.4646 0.4646
Loa Loa (eye worm) RGC/RGC protein kinase 0.0348 0.4646 0.7407
Entamoeba histolytica tyrosine kinase, putative 0.0348 0.4646 0.892
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0147 0.1819 0.6203
Echinococcus granulosus tyrosine protein kinase Fyn 0.0348 0.4646 0.4645
Trichomonas vaginalis maltase-glucoamylase, putative 0.0032 0.0197 0.0321
Echinococcus granulosus kinase suppressor of Ras 1 0.0348 0.4646 0.4645
Trypanosoma brucei leucine-rich repeat protein (LRRP), putative 0.004 0.03 0.0398
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0225 0.2916 0.5428
Mycobacterium ulcerans beta-lactamase 0.0063 0.0628 0.1577
Trichomonas vaginalis protein phosphatase 2C, putative 0.004 0.03 0.0513
Trichomonas vaginalis set domain proteins, putative 0.0398 0.535 1
Entamoeba histolytica protein kinase domain containing protein 0.0348 0.4646 0.892
Schistosoma mansoni tyrosine kinase 0.0348 0.4646 0.4646
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0225 0.2916 0.5428
Echinococcus granulosus leucine rich repeat and fibronectin type III 0.004 0.03 0.0297
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0089 0.0996 0.1588
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0095 0.1084 0.1728
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0333 0.4442 0.4441
Mycobacterium tuberculosis Conserved hypothetical protein 0.0291 0.3843 0.6069
Echinococcus multilocularis FL cytokine receptor 0.0348 0.4646 0.4645
Mycobacterium ulcerans hypothetical protein 0.0063 0.0628 0.1577
Onchocerca volvulus Heterochromatin protein 1 homolog 0.003 0.0165 0.0303
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0348 0.4646 0.6171
Toxoplasma gondii STE kinase 0.0348 0.4646 1
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0047 0.04 0.0638
Schistosoma mansoni tyrosine kinase 0.0348 0.4646 0.4646
Plasmodium vivax hypothetical protein, conserved 0.0063 0.0628 0.1348
Mycobacterium tuberculosis Probable lipase LipD 0.0063 0.0628 0.0957
Trichomonas vaginalis podocan, putative 0.004 0.03 0.0513
Entamoeba histolytica tyrosin kinase, putative 0.0348 0.4646 0.892
Brugia malayi Furin-like cysteine rich region family protein 0.0348 0.4646 0.7408
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0095 0.1084 0.1082
Echinococcus granulosus leucine rich repeat containing protein 40 0.004 0.03 0.0297
Giardia lamblia Kinase, NEK 0.0348 0.4646 1
Brugia malayi Leucine Rich Repeat family protein 0.004 0.03 0.0478
Schistosoma mansoni hypothetical protein 0.0056 0.0535 0.0535
Entamoeba histolytica protein kinase domain containing protein 0.0348 0.4646 0.892
Trichomonas vaginalis TKL family protein kinase 0.0348 0.4646 0.8678
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0348 0.4646 0.4645
Trichomonas vaginalis TKL family protein kinase 0.0348 0.4646 0.8678
Trypanosoma cruzi hypothetical protein, conserved 0.0115 0.1366 0.1785
Trichomonas vaginalis chromobox protein, putative 0.0054 0.0497 0.0884
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0033 0.0205 0.0205
Schistosoma mansoni protein kinase 0.0348 0.4646 0.4646
Brugia malayi Thioredoxin reductase 0.0184 0.2333 0.372
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0027 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0348 0.4646 0.8678
Mycobacterium tuberculosis Probable dehydrogenase 0.0419 0.5655 0.895
Echinococcus multilocularis protein kinase 0.0348 0.4646 0.4645
Schistosoma mansoni tyrosine kinase 0.0348 0.4646 0.4646
Entamoeba histolytica protein kinase domain containing protein 0.0348 0.4646 0.892
Entamoeba histolytica hypothetical protein 0.0348 0.4646 0.892
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0348 0.4646 0.4645
Loa Loa (eye worm) hypothetical protein 0.0348 0.4646 0.7407
Entamoeba histolytica protein kinase, putative 0.0348 0.4646 0.892
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0466 0.6315 1
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0032 0.0197 0.0227
Trichomonas vaginalis toll, putative 0.004 0.03 0.0513
Loa Loa (eye worm) hypothetical protein 0.0115 0.1366 0.2175
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0387 0.5206 1
Trichomonas vaginalis conserved hypothetical protein 0.004 0.03 0.0513
Echinococcus multilocularis tissue type plasminogen activator 0.0115 0.1366 0.1364
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0348 0.4646 0.892
Schistosoma mansoni chromobox protein 0.0054 0.0497 0.0497
Loa Loa (eye worm) latrophilin receptor protein 2 0.0028 0.0138 0.0215
Echinococcus granulosus GPCR family 2 0.0028 0.0138 0.0135
Loa Loa (eye worm) hypothetical protein 0.004 0.03 0.0474
Schistosoma mansoni hypothetical protein 0.004 0.03 0.03
Entamoeba histolytica leucine rich repeat and phosphatase domain containing protein 0.004 0.03 0.0527
Onchocerca volvulus 0.004 0.03 0.0556
Trichomonas vaginalis sucrase-isomaltase, putative 0.0032 0.0197 0.0321
Echinococcus multilocularis peroxidasin 0.004 0.03 0.0297
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0348 0.4646 0.8684
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0105 0.122 0.1898
Schistosoma mansoni tyrosine kinase 0.0348 0.4646 0.4646
Onchocerca volvulus 0.004 0.03 0.0556
Echinococcus multilocularis PHD finger protein rhinoceros 0.0056 0.0535 0.0532
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0064 0.0639 0.0848
Loa Loa (eye worm) hypothetical protein 0.004 0.03 0.0474
Echinococcus granulosus ras suppressor protein 1 0.004 0.03 0.0297
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0032 0.0197 0.0321
Onchocerca volvulus 0.0348 0.4646 0.8684
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0064 0.0639 0.0639
Trichomonas vaginalis TKL family protein kinase 0.0348 0.4646 0.8678
Loa Loa (eye worm) hypothetical protein 0.0147 0.1819 0.2897
Brugia malayi beta-lactamase family protein 0.0063 0.0628 0.1002
Entamoeba histolytica protein kinase domain containing protein 0.0348 0.4646 0.892
Echinococcus multilocularis jumonji domain containing 1A 0.0032 0.0197 0.0194
Entamoeba histolytica protein kinase, putative 0.0348 0.4646 0.892
Trichomonas vaginalis TKL family protein kinase 0.0348 0.4646 0.8678
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0225 0.2916 0.5428
Trichomonas vaginalis TKL family protein kinase 0.0348 0.4646 0.8678
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0025 0.01 0.0116
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0047 0.04 0.0638
Loa Loa (eye worm) heterochromatin protein 1 0.0054 0.0497 0.0789
Echinococcus multilocularis serotonin transporter 0.0109 0.1285 0.1283
Echinococcus multilocularis tyrosine protein kinase csk 0.0348 0.4646 0.4645
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0063 0.0628 0.0628
Loa Loa (eye worm) TK protein kinase 0.0348 0.4646 0.7407
Brugia malayi Leucine Rich Repeat family protein 0.004 0.03 0.0478
Onchocerca volvulus 0.0024 0.0073 0.0132
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0348 0.4646 0.6157
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0348 0.4646 0.7407
Brugia malayi bone morphogenetic protein type 1 receptor 0.0348 0.4646 0.7408
Schistosoma mansoni hypothetical protein 0.004 0.03 0.03
Schistosoma mansoni hypothetical protein 0.004 0.03 0.03
Trichomonas vaginalis TKL family protein kinase 0.0348 0.4646 0.8678
Loa Loa (eye worm) hypothetical protein 0.004 0.03 0.0474
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0348 0.4646 0.892
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0348 0.4646 0.4645
Entamoeba histolytica villidin, putative 0.004 0.03 0.0527
Entamoeba histolytica protein kinase, putative 0.0348 0.4646 0.892
Giardia lamblia hypothetical protein 0.004 0.03 0.0591
Toxoplasma gondii kringle domain-containing protein 0.0115 0.1366 0.294
Trypanosoma cruzi leucine-rich repeat protein, putative 0.004 0.03 0.0364
Brugia malayi integrin-linked kinase 0.0348 0.4646 0.7408
Trichomonas vaginalis TKL family protein kinase 0.0348 0.4646 0.8678
Schistosoma mansoni protein kinase 0.0348 0.4646 0.4646
Entamoeba histolytica serine/threonine kinase, putative 0.0348 0.4646 0.892
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0348 0.4646 0.4645
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0027 0.0052
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0064 0.0639 0.137
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0064 0.0639 0.0816
Mycobacterium tuberculosis Probable lipase LipE 0.0063 0.0628 0.0957
Schistosoma mansoni protein kinase 0.0348 0.4646 0.4646
Schistosoma mansoni protein tyrosine kinase 0.0348 0.4646 0.4646
Onchocerca volvulus 0.0398 0.535 1
Brugia malayi Protein kinase domain containing protein 0.0348 0.4646 0.7408
Brugia malayi jmjC domain containing protein 0.0032 0.0197 0.0314
Entamoeba histolytica serine/threonine kinase, putative 0.0348 0.4646 0.892
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0348 0.4646 0.892
Entamoeba histolytica cysteine surface protein, putative 0.0348 0.4646 0.892
Echinococcus granulosus phd:f box containing protein 0.0032 0.0197 0.0194
Schistosoma mansoni shoc2 0.004 0.03 0.03
Trichomonas vaginalis conserved hypothetical protein 0.0348 0.4646 0.8678
Brugia malayi follicle stimulating hormone receptor 0.0409 0.5514 0.8791
Trypanosoma brucei Basal body protein 0.004 0.03 0.0398
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0064 0.0639 0.137
Echinococcus granulosus neutral alpha glucosidase AB 0.0032 0.0197 0.0195
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0348 0.4646 0.4646
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0115 0.1366 0.2936
Trichomonas vaginalis alpha-glucosidase, putative 0.0032 0.0197 0.0321
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0333 0.4442 0.7083
Plasmodium falciparum leucine-rich repeat protein 0.004 0.03 0.064
Loa Loa (eye worm) sur-8-PB 0.004 0.03 0.0474
Loa Loa (eye worm) hypothetical protein 0.0348 0.4646 0.7407
Loa Loa (eye worm) TK/FER protein kinase 0.0348 0.4646 0.7407
Schistosoma mansoni ephrin receptor 0.0348 0.4646 0.4646
Brugia malayi Protein kinase domain containing protein 0.0348 0.4646 0.7408
Echinococcus multilocularis lysine specific demethylase 6a 0.0032 0.0197 0.0194
Trichomonas vaginalis TKL family protein kinase 0.0348 0.4646 0.8678
Schistosoma mansoni tyrosine kinase 0.0348 0.4646 0.4646
Echinococcus granulosus tyrosine protein kinase Fyn 0.0348 0.4646 0.4645
Loa Loa (eye worm) CCR4-NOT transcription complex subunit 6 family protein 0.0044 0.0358 0.0567
Echinococcus multilocularis leucine rich repeat and death domain containing protein 0.004 0.03 0.0297
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0064 0.0639 0.0816
Trichomonas vaginalis TKL family protein kinase 0.0348 0.4646 0.8678
Trichomonas vaginalis TKL family protein kinase 0.0348 0.4646 0.8678
Loa Loa (eye worm) leucine Rich Repeat family protein 0.004 0.03 0.0474
Brugia malayi mbt repeat family protein 0.0084 0.092 0.1468
Echinococcus granulosus protein kinase 0.0348 0.4646 0.4645
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0225 0.2916 0.5579
Entamoeba histolytica hypothetical protein, conserved 0.0348 0.4646 0.892
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0027 0.0035
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0238 0.3092 0.3091
Echinococcus granulosus protein flightless 1 0.004 0.03 0.0297
Trichomonas vaginalis conserved hypothetical protein 0.0348 0.4646 0.8678
Echinococcus granulosus tyrosine kinase 0.0348 0.4646 0.4645
Brugia malayi Leucine Rich Repeat family protein 0.004 0.03 0.0478
Entamoeba histolytica hypothetical protein 0.0066 0.0665 0.1233
Giardia lamblia Hypothetical protein 0.004 0.03 0.0591
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0019 0.0003 0.0003
Trypanosoma brucei trypanothione reductase 0.0184 0.2333 0.3099
Loa Loa (eye worm) TK/FER protein kinase 0.0348 0.4646 0.7407
Leishmania major hypothetical protein, conserved 0.004 0.03 0.0364
Entamoeba histolytica DnaJ family protein 0.004 0.03 0.0527
Loa Loa (eye worm) TK protein kinase 0.0348 0.4646 0.7407
Loa Loa (eye worm) hypothetical protein 0.003 0.0165 0.0259
Entamoeba histolytica ankyrin repeat protein 0.0348 0.4646 0.892
Brugia malayi hypothetical protein 0.0066 0.0665 0.1061
Echinococcus granulosus leucine rich repeat and coiled coil 0.004 0.03 0.0297
Echinococcus multilocularis polycomb protein SCMH1 0.0084 0.092 0.0918
Trichomonas vaginalis leucine-rich repeat-containing protein 17, lrc17, putative 0.004 0.03 0.0513
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0095 0.1084 0.1082
Schistosoma mansoni protein kinase 0.0348 0.4646 0.4646
Onchocerca volvulus Tyrosine kinase homolog 0.0348 0.4646 0.8684
Trichomonas vaginalis TKL family protein kinase 0.0348 0.4646 0.8678
Brugia malayi ras-binding protein SUR-8 0.004 0.03 0.0478
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0147 0.1819 1
Schistosoma mansoni sodium/chloride dependent transporter 0.0109 0.1285 0.1285
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0419 0.5655 0.895
Schistosoma mansoni hypothetical protein 0.0028 0.0138 0.0138
Entamoeba histolytica protein kinase domain containing protein 0.0348 0.4646 0.892
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0064 0.0639 0.1604
Loa Loa (eye worm) hypothetical protein 0.0348 0.4646 0.7407
Loa Loa (eye worm) hypothetical protein 0.0061 0.0599 0.0951
Loa Loa (eye worm) TK/Met protein kinase 0.0348 0.4646 0.7407
Giardia lamblia NADH oxidase lateral transfer candidate 0.0064 0.0639 0.1325
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0419 0.5655 0.895
Toxoplasma gondii leucine rich repeat-containing protein 0.004 0.03 0.0645
Entamoeba histolytica tyrosine kinase, putative 0.0348 0.4646 0.892
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0348 0.4646 0.4645
Trypanosoma cruzi protein phosphatase 1, regulatory subunit, putative 0.004 0.03 0.0364
Loa Loa (eye worm) TK/FER protein kinase 0.0348 0.4646 0.7407
Loa Loa (eye worm) hypothetical protein 0.004 0.03 0.0474
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0084 0.092 0.1717
Loa Loa (eye worm) hypothetical protein 0.0063 0.0628 0.0998
Loa Loa (eye worm) hypothetical protein 0.0348 0.4646 0.7407
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0348 0.4646 0.4645
Entamoeba histolytica protein kinase, putative 0.0348 0.4646 0.892
Echinococcus granulosus PHD finger protein rhinoceros 0.0056 0.0535 0.0532
Echinococcus granulosus peptidase Clp S14 family 0.0097 0.1103 0.1101
Brugia malayi Protein kinase domain containing protein 0.0348 0.4646 0.7408
Echinococcus multilocularis tyrosine protein kinase pr2 0.0348 0.4646 0.4645
Trichomonas vaginalis TKL family protein kinase 0.0348 0.4646 0.8678
Loa Loa (eye worm) hypothetical protein 0.0109 0.1285 0.2046
Leishmania major protein kinase, putative 0.0348 0.4646 0.6157
Loa Loa (eye worm) mbt repeat family protein 0.0084 0.092 0.1464
Trichomonas vaginalis TKL family protein kinase 0.0348 0.4646 0.8678
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0333 0.4442 0.4441
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0053 0.0491 0.0488
Schistosoma mansoni cpg binding protein 0.0054 0.0502 0.0502
Schistosoma mansoni myelin transcription factor 1 myt1 0.0095 0.1084 0.1084
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0078 0.0835 0.1078
Trichomonas vaginalis protein phosphatase 2C delta isoform, putative 0.004 0.03 0.0513
Entamoeba histolytica protein kinase, putative 0.0348 0.4646 0.892
Brugia malayi Protein kinase domain containing protein 0.0348 0.4646 0.7408
Trichomonas vaginalis leucine-rich repeat-containing protein, putative 0.004 0.03 0.0513
Trichomonas vaginalis TKL family protein kinase 0.0348 0.4646 0.8678
Trichomonas vaginalis leucine-rich repeat protein, BspA family 0.004 0.03 0.0513
Brugia malayi MH2 domain containing protein 0.0099 0.1144 0.1824
Echinococcus granulosus geminin 0.0551 0.7508 0.7507
Loa Loa (eye worm) TK protein kinase 0.0348 0.4646 0.7407
Loa Loa (eye worm) hypothetical protein 0.0348 0.4646 0.7407
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0419 0.5655 0.895
Loa Loa (eye worm) SRC-1 0.0348 0.4646 0.7407
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0348 0.4646 0.4645
Trichomonas vaginalis TKL family protein kinase 0.0348 0.4646 0.8678
Entamoeba histolytica hypothetical protein 0.0348 0.4646 0.892
Schistosoma mansoni hypothetical protein 0.004 0.03 0.03
Trypanosoma brucei PAB1-binding protein , putative 0.0023 0.0059 0.0078
Trichomonas vaginalis chromobox protein, putative 0.0054 0.0497 0.0884
Schistosoma mansoni serine/threonine protein kinase 0.0348 0.4646 0.4646
Loa Loa (eye worm) norepinephrine transporter 0.0109 0.1285 0.2046
Brugia malayi Kringle domain containing protein 0.0115 0.1366 0.2178
Trypanosoma cruzi hypothetical protein, conserved 0.0063 0.0628 0.0802
Toxoplasma gondii thioredoxin reductase 0.0184 0.2333 0.5021
Onchocerca volvulus 0.0348 0.4646 0.8684
Schistosoma mansoni tyrosine kinase 0.0348 0.4646 0.4646
Echinococcus multilocularis activated cdc42 kinase 1 0.0348 0.4646 0.4645
Plasmodium falciparum ataxin-2 like protein, putative 0.0023 0.0059 0.0122
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0019 0.0003 0.0004
Schistosoma mansoni jumonji/arid domain-containing protein 0.0124 0.1493 0.1493
Schistosoma mansoni cpg binding protein 0.0051 0.0461 0.0461
Echinococcus granulosus SAM and MBT domain containing protein 0.0084 0.092 0.0918
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0348 0.4646 0.4646
Loa Loa (eye worm) TK/FER protein kinase 0.0348 0.4646 0.7407
Mycobacterium ulcerans esterase/lipase LipP 0.0063 0.0628 0.1577
Entamoeba histolytica tyrosine kinase, putative 0.0348 0.4646 0.892
Echinococcus granulosus JmjC domain containing protein 4 0.0032 0.0197 0.0194
Loa Loa (eye worm) TK protein kinase 0.0348 0.4646 0.7407
Schistosoma mansoni hypothetical protein 0.0085 0.0935 0.0935
Schistosoma mansoni tyrosine kinase 0.0348 0.4646 0.4646
Echinococcus multilocularis Leucine rich repeat domain containing protein 0.004 0.03 0.0297
Trichomonas vaginalis TKL family protein kinase 0.0348 0.4646 0.8678
Brugia malayi jmjC domain containing protein 0.0032 0.0197 0.0314
Entamoeba histolytica hypothetical protein 0.0387 0.5206 1
Entamoeba histolytica tyrosine kinase, putative 0.0348 0.4646 0.892
Brugia malayi Protein kinase domain containing protein 0.0348 0.4646 0.7408
Entamoeba histolytica ankyrin repeat protein 0.0348 0.4646 0.892
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0064 0.0639 0.0848
Loa Loa (eye worm) TK/FER protein kinase 0.0348 0.4646 0.7407
Schistosoma mansoni sodium/chloride dependent transporter 0.0019 0.0003 0.0003
Echinococcus multilocularis transfer RNA-Thr 0.0348 0.4646 0.4645
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0225 0.2916 0.5428
Plasmodium vivax glutathione reductase, putative 0.0184 0.2333 0.5019
Echinococcus multilocularis leucine rich repeat containing protein 70 0.004 0.03 0.0297
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0348 0.4646 0.8678
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0409 0.5514 0.8791
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0348 0.4646 0.892
Toxoplasma gondii hypothetical protein 0.0089 0.0997 0.2145
Loa Loa (eye worm) TK/FER protein kinase 0.0348 0.4646 0.7407
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0105 0.122 0.1218
Leishmania major hypothetical protein, conserved 0.004 0.03 0.0364
Echinococcus granulosus leucine rich repeat protein soc 2 0.004 0.03 0.0297
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0028 0.0142 0.0301
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0147 0.1819 0.3912
Loa Loa (eye worm) leucine Rich Repeat family protein 0.004 0.03 0.0474
Echinococcus multilocularis tyrosine kinase 0.0348 0.4646 0.4645
Mycobacterium tuberculosis Probable oxidoreductase 0.0466 0.6315 1
Schistosoma mansoni protein phosphatases pp1 regulatory subunit 0.004 0.03 0.03
Trichomonas vaginalis TKL family protein kinase 0.0348 0.4646 0.8678
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0028 0.0142 0.0153
Brugia malayi Leucine Rich Repeat family protein 0.004 0.03 0.0478
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0146 0.18 0.2868
Onchocerca volvulus 0.0051 0.0461 0.0857
Onchocerca volvulus 0.0348 0.4646 0.8684
Toxoplasma gondii LsmAD domain-containing protein 0.0023 0.0059 0.0127
Trypanosoma cruzi protein phosphatase 1, regulatory subunit, putative 0.004 0.03 0.0364
Brugia malayi Protein kinase domain containing protein 0.0463 0.6272 1
Schistosoma mansoni slit 0.004 0.03 0.03
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0225 0.2916 0.5428
Trypanosoma brucei leucine-rich repeat protein (LRRP), putative 0.004 0.03 0.0398
Brugia malayi CCR4 0.0044 0.0358 0.057
Entamoeba histolytica protein kinase domain containing protein 0.0348 0.4646 0.892
Plasmodium vivax thioredoxin reductase, putative 0.0184 0.2333 0.5019
Loa Loa (eye worm) hypothetical protein 0.004 0.03 0.0474
Brugia malayi Protein kinase domain containing protein 0.0348 0.4646 0.7408
Echinococcus granulosus leucine rich repeat and calponin y 0.004 0.03 0.0297
Entamoeba histolytica tyrosin kinase, putative 0.0348 0.4646 0.892
Echinococcus granulosus serotonin transporter 0.0109 0.1285 0.1283
Toxoplasma gondii histone lysine methyltransferase SET1 0.0099 0.1131 0.2434
Echinococcus granulosus leucine rich repeat neuronal protein 0.004 0.03 0.0297
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0078 0.0835 0.111
Brugia malayi Protein kinase domain containing protein 0.0348 0.4646 0.7408
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0348 0.4646 0.892
Trypanosoma brucei Outer row dynein-assembly protein 7 0.004 0.03 0.0398
Onchocerca volvulus 0.0348 0.4646 0.8684
Trichomonas vaginalis conserved hypothetical protein 0.0348 0.4646 0.8678
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0348 0.4646 0.4645
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0051 0.0461 0.0992
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0261 0.3426 0.4551
Mycobacterium ulcerans aldehyde dehydrogenase 0.0053 0.0491 0.1216
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0348 0.4646 0.4645
Echinococcus multilocularis leucine rich repeat and calponin y 0.004 0.03 0.0297
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0028 0.0142 0.0153
Plasmodium falciparum glutathione reductase 0.0064 0.0639 0.137
Entamoeba histolytica protein kinase domain containing protein 0.0348 0.4646 0.892
Echinococcus multilocularis leucine rich repeat neuronal protein leucine rich repeat containing protein 0.004 0.03 0.0297
Trichomonas vaginalis leucine-rich transmembrane proteins, putative 0.004 0.03 0.0513
Trypanosoma cruzi trypanothione reductase, putative 0.0184 0.2333 0.3074
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0348 0.4646 0.4645
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0095 0.1075 0.1711
Toxoplasma gondii hypothetical protein 0.0019 0.0003 0.0005
Trichomonas vaginalis TKL family protein kinase 0.0348 0.4646 0.8678
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0348 0.4646 0.892
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0032 0.0197 0.0261
Trichomonas vaginalis TKL family protein kinase 0.0348 0.4646 0.8678
Trichomonas vaginalis TKL family protein kinase 0.0348 0.4646 0.8678
Entamoeba histolytica protein kinase, putative 0.0387 0.5206 1
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0032 0.0197 0.033
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0019 0.0003 0.0003
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0348 0.4646 0.7408
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0348 0.4646 0.4645
Toxoplasma gondii leucine rich repeat-containing protein 0.004 0.03 0.0645
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0097 0.1103 0.1614
Trichomonas vaginalis TKL family protein kinase 0.0348 0.4646 0.8678
Loa Loa (eye worm) TK/ALK protein kinase 0.0348 0.4646 0.7407
Echinococcus granulosus Leucine rich repeat typical subtype 0.004 0.03 0.0297
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0348 0.4646 0.4645
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0028 0.0142 0.0222
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0348 0.4646 0.4645
Loa Loa (eye worm) leucine Rich Repeat family protein 0.004 0.03 0.0474
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0348 0.4646 1
Schistosoma mansoni tyrosine kinase 0.0348 0.4646 0.4646
Trichomonas vaginalis TKL family protein kinase 0.0348 0.4646 0.8678
Entamoeba histolytica protein kinase domain containing protein 0.0348 0.4646 0.892
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0064 0.0639 0.0816
Loa Loa (eye worm) TK protein kinase 0.0348 0.4646 0.7407
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0051 0.0461 0.0459
Brugia malayi Protein kinase domain containing protein 0.0348 0.4646 0.7408
Echinococcus multilocularis Leucine rich repeat, typical subtype 0.004 0.03 0.0297
Onchocerca volvulus 0.006 0.0585 0.1089
Echinococcus multilocularis jumonji domain containing protein 0.0078 0.0846 0.0844
Onchocerca volvulus 0.0348 0.4646 0.8684
Onchocerca volvulus Alhambra homolog 0.0056 0.0535 0.0995
Trichomonas vaginalis TKL family protein kinase 0.0348 0.4646 0.8678
Trichomonas vaginalis TKL family protein kinase 0.0348 0.4646 0.8678
Mycobacterium tuberculosis Conserved protein 0.0063 0.0628 0.0957
Echinococcus multilocularis protein phosphatase 1 regulatory subunit 7 0.004 0.03 0.0297
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0063 0.0628 0.0628
Echinococcus multilocularis kinase suppressor of Ras 1 0.0348 0.4646 0.4645
Echinococcus granulosus histone acetyltransferase MYST2 0.0095 0.1084 0.1082
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0109 0.1285 0.1285
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0238 0.3092 0.3091
Echinococcus multilocularis neutral alpha glucosidase AB 0.0032 0.0197 0.0195
Mycobacterium leprae Probable lipase LipE 0.0063 0.0628 0.0851
Loa Loa (eye worm) hypothetical protein 0.0063 0.0628 0.0998
Loa Loa (eye worm) hypothetical protein 0.0109 0.1285 0.2046
Mycobacterium tuberculosis Probable reductase 0.0419 0.5655 0.895
Schistosoma mansoni ap endonuclease 0.002 0.0027 0.0027
Loa Loa (eye worm) leucine Rich Repeat family protein 0.004 0.03 0.0474
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0064 0.0639 0.0636
Brugia malayi jmjC domain containing protein 0.0032 0.0197 0.0314
Loa Loa (eye worm) hypothetical protein 0.0023 0.0059 0.009
Trichomonas vaginalis leucine-rich transmembrane protein, putative 0.004 0.03 0.0513
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0348 0.4646 0.7407
Loa Loa (eye worm) leucine Rich Repeat family protein 0.004 0.03 0.0474
Trichomonas vaginalis TKL family protein kinase 0.0348 0.4646 0.8678
Trichomonas vaginalis TKL family protein kinase 0.0348 0.4646 0.8678
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0348 0.4646 0.4645
Entamoeba histolytica leucine rich repeat / protein phosphatase 2C domain containing protein 0.004 0.03 0.0527
Loa Loa (eye worm) hypothetical protein 0.0348 0.4646 0.7407
Echinococcus granulosus leucine rich repeat 0.004 0.03 0.0297
Echinococcus granulosus tyrosine protein kinase pr2 0.0348 0.4646 0.4645
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0032 0.0197 0.0425
Brugia malayi Protein kinase domain containing protein 0.0348 0.4646 0.7408
Trypanosoma brucei leucine-rich repeat protein (LRRP), putative 0.004 0.03 0.0398
Loa Loa (eye worm) hypothetical protein 0.0348 0.4646 0.7407
Trypanosoma brucei Pseudokinase, putative 0.0348 0.4646 0.6171
Trichomonas vaginalis TKL family protein kinase 0.0348 0.4646 0.8678
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0019 0.0003 0.0003
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0348 0.4646 0.7408
Echinococcus multilocularis leucine rich repeat protein soc 2 0.004 0.03 0.0297
Loa Loa (eye worm) hypothetical protein 0.0063 0.0628 0.0998
Loa Loa (eye worm) jmjC domain-containing protein 0.0116 0.1381 0.2199
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0063 0.0628 0.1577
Loa Loa (eye worm) TK/ROR protein kinase 0.0463 0.6272 1
Trichomonas vaginalis chromobox protein, putative 0.0032 0.0197 0.032
Trichomonas vaginalis TKL family protein kinase 0.0348 0.4646 0.8678
Echinococcus multilocularis lysine specific demethylase 5A 0.0121 0.1452 0.145
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0348 0.4646 0.4646
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0035 0.0238 0.0235
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0348 0.4646 1
Echinococcus multilocularis peptidase Clp (S14 family) 0.0097 0.1103 0.1101
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0027 0.0043
Loa Loa (eye worm) hypothetical protein 0.0109 0.1285 0.2046
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0348 0.4646 0.4645
Brugia malayi Latrophilin receptor protein 2 0.0028 0.0138 0.0219
Plasmodium falciparum thioredoxin reductase 0.0064 0.0639 0.137
Brugia malayi Leucine Rich Repeat family protein 0.004 0.03 0.0478
Brugia malayi Protein kinase domain containing protein 0.004 0.03 0.0478
Echinococcus granulosus leucine rich repeat containing protein 47 0.004 0.03 0.0297
Entamoeba histolytica leucine rich repeat / protein phosphatase 2C domain containing protein 0.004 0.03 0.0527
Echinococcus granulosus lysine specific demethylase 5A 0.0124 0.1493 0.1491
Leishmania major protein kinase, putative 0.0348 0.4646 0.6157
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0028 0.0138 0.0135
Brugia malayi Leucine Rich Repeat family protein 0.004 0.03 0.0478
Echinococcus multilocularis variable lymphocyte receptor 0.004 0.03 0.0297
Brugia malayi protein-tyrosine kinase 0.0348 0.4646 0.7408
Trichomonas vaginalis TKL family protein kinase 0.0348 0.4646 0.8678
Loa Loa (eye worm) leucine Rich Repeat family protein 0.004 0.03 0.0474
Trichomonas vaginalis TK family protein kinase 0.0348 0.4646 0.8678
Trichomonas vaginalis protein phosphatases pp1 regulatory subunit, putative 0.004 0.03 0.0513
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0032 0.0197 0.0321
Brugia malayi Leucine Rich Repeat family protein 0.004 0.03 0.0478
Loa Loa (eye worm) TK/FER protein kinase 0.0348 0.4646 0.7407
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0089 0.0996 0.1585
Loa Loa (eye worm) hypothetical protein 0.0348 0.4646 0.7407
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0051 0.0456 0.0574
Brugia malayi PHD-finger family protein 0.0056 0.0535 0.0853
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0165 0.0259
Echinococcus granulosus polycomb protein SCMH1 0.0084 0.092 0.0918
Loa Loa (eye worm) hypothetical protein 0.004 0.03 0.0474
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0348 0.4646 0.4645
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0027 0.0001
Echinococcus granulosus cpg binding protein 0.0054 0.0502 0.0499
Leishmania major hypothetical protein, conserved 0.004 0.03 0.0364
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0056 0.0535 0.0535
Entamoeba histolytica hypothetical protein 0.0348 0.4646 0.892
Brugia malayi Protein kinase domain containing protein 0.0348 0.4646 0.7408
Leishmania major leucine-rich repeat protein, putative 0.004 0.03 0.0364
Brugia malayi Receptor family ligand binding region containing protein 0.0348 0.4646 0.7408
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0028 0.0142 0.0188
Loa Loa (eye worm) hypothetical protein 0.0063 0.0628 0.0998
Echinococcus granulosus leucine rich repeat containing protein 70 0.004 0.03 0.0297
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0348 0.4646 0.4645
Brugia malayi Leucine Rich Repeat family protein 0.004 0.03 0.0478
Trichomonas vaginalis TKL family protein kinase 0.0348 0.4646 0.8678
Leishmania major trypanothione reductase 0.0184 0.2333 0.3074
Trichomonas vaginalis TKL family protein kinase 0.0348 0.4646 0.8678
Brugia malayi hypothetical protein 0.0348 0.4646 0.7408
Toxoplasma gondii NADPH-glutathione reductase 0.0064 0.0639 0.1375
Loa Loa (eye worm) serine/threonine protein kinase 0.0348 0.4646 0.7407
Brugia malayi Leucine Rich Repeat family protein 0.004 0.03 0.0478
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0348 0.4646 0.892
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0552 0.7529 1
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0419 0.5655 0.8938
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0028 0.0142 0.0305
Echinococcus multilocularis protein tyrosine kinase 0.0348 0.4646 0.4645
Onchocerca volvulus 0.0109 0.1285 0.2398
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0064 0.0639 0.0816
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0064 0.0639 0.0636
Echinococcus multilocularis ras suppressor protein 1 0.004 0.03 0.0297
Trichomonas vaginalis alpha-glucosidase, putative 0.0032 0.0197 0.0321
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0064 0.0639 0.0816
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0064 0.0639 0.3415
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0147 0.1819 0.4696
Echinococcus granulosus slit 1 protein 0.004 0.03 0.0297
Echinococcus multilocularis leucine rich repeat containing protein 15 0.004 0.03 0.0297
Loa Loa (eye worm) MBCTL1 0.0095 0.1084 0.1725
Loa Loa (eye worm) TK/INSR protein kinase 0.0348 0.4646 0.7407
Echinococcus multilocularis lysosomal alpha glucosidase 0.0146 0.18 0.1798
Onchocerca volvulus 0.0084 0.0932 0.1738
Echinococcus granulosus leucine rich repeat containing protein 0.004 0.03 0.0297
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0064 0.0639 0.3415
Echinococcus multilocularis inositol monophosphatase 1 0.0028 0.0142 0.0139
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0402 0.5414 0.8568
Echinococcus granulosus lysine specific demethylase 6a 0.0032 0.0197 0.0194
Loa Loa (eye worm) TK/FAK protein kinase 0.0348 0.4646 0.7407
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0063 0.0628 0.1002
Loa Loa (eye worm) TK/EPH protein kinase 0.0348 0.4646 0.7407
Mycobacterium leprae conserved hypothetical protein 0.0063 0.0628 0.0851
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0147 0.1819 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0348 0.4646 0.892
Entamoeba histolytica hypothetical protein 0.0066 0.0665 0.1233
Echinococcus granulosus activin receptor type 0.0348 0.4646 0.4645
Entamoeba histolytica protein kinase domain containing protein 0.0348 0.4646 0.892
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0032 0.0197 0.0423
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0348 0.4646 0.892
Entamoeba histolytica protein kinase domain containing protein 0.0348 0.4646 0.892
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0348 0.4646 1
Echinococcus granulosus activated cdc42 kinase 1 0.0348 0.4646 0.4645
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0051 0.0456 0.0978
Entamoeba histolytica tyrosine kinase, putative 0.0348 0.4646 0.892
Loa Loa (eye worm) jmjC domain-containing protein 0.0032 0.0197 0.031
Trichomonas vaginalis TKL family protein kinase 0.0348 0.4646 0.8678
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0348 0.4646 0.892
Toxoplasma gondii protein kinase 0.0348 0.4646 1
Schistosoma mansoni hypothetical protein 0.0066 0.0665 0.0665
Loa Loa (eye worm) hypothetical protein 0.004 0.03 0.0474
Schistosoma mansoni hypothetical protein 0.0348 0.4646 0.4646
Brugia malayi Protein kinase domain containing protein 0.0348 0.4646 0.7408
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0261 0.3426 0.4532
Echinococcus multilocularis slit 2 protein 0.004 0.03 0.0297
Trichomonas vaginalis TKL family protein kinase 0.0348 0.4646 0.8678
Brugia malayi Leucine Rich Repeat family protein 0.004 0.03 0.0478
Echinococcus granulosus survival motor neuron protein 1 0.0415 0.5597 0.5596
Brugia malayi beta-lactamase family protein 0.0063 0.0628 0.1002
Entamoeba histolytica leucine rich repeat / protein phosphatase 2C domain containing protein 0.004 0.03 0.0527
Echinococcus granulosus tissue type plasminogen activator 0.0115 0.1366 0.1364
Loa Loa (eye worm) hypothetical protein 0.0051 0.0461 0.0731
Leishmania major proteophosphoglycan ppg1 0.004 0.03 0.0364
Echinococcus granulosus tyrosine protein kinase Blk 0.0348 0.4646 0.4645
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0333 0.4442 0.4442
Entamoeba histolytica protein kinase domain containing protein 0.0348 0.4646 0.892
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0063 0.0628 0.0957
Trypanosoma brucei Flagellum attachment zone protein 20 0.0348 0.4646 0.6171
Echinococcus granulosus natriuretic peptide receptor 1 0.0348 0.4646 0.4645
Echinococcus multilocularis leucine rich repeat protein 1 0.004 0.03 0.0297
Brugia malayi Tyrosine-protein kinase PR2 0.0348 0.4646 0.7408
Giardia lamblia Kinase, NEK 0.0348 0.4646 1
Brugia malayi Leucine Rich Repeat family protein 0.004 0.03 0.0478
Schistosoma mansoni serine/threonine protein kinase 0.0348 0.4646 0.4646
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0032 0.0197 0.0197
Brugia malayi Immunoglobulin I-set domain containing protein 0.0348 0.4646 0.7408
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0064 0.0639 0.3503
Echinococcus multilocularis leucine rich repeat containing protein 57 0.004 0.03 0.0297
Loa Loa (eye worm) hypothetical protein 0.004 0.03 0.0474
Loa Loa (eye worm) TK protein kinase 0.0348 0.4646 0.7407
Schistosoma mansoni hypothetical protein 0.0551 0.7508 0.7508
Echinococcus granulosus slit 2 protein 0.004 0.03 0.0297
Leishmania major hypothetical protein, conserved 0.0023 0.0059 0.0043
Schistosoma mansoni alpha-glucosidase 0.0126 0.1513 0.1513
Schistosoma mansoni tyrosine kinase 0.0348 0.4646 0.4646
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0348 0.4646 0.4646
Echinococcus multilocularis leucine rich repeat containing protein 24 0.004 0.03 0.0297
Echinococcus multilocularis Leucine rich repeat, typical subtype 0.004 0.03 0.0297
Loa Loa (eye worm) TK/ABL protein kinase 0.0348 0.4646 0.7407
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0019 0.0003 0.0003
Brugia malayi Protein kinase domain containing protein 0.0348 0.4646 0.7408
Brugia malayi Immunoglobulin I-set domain containing protein 0.004 0.03 0.0478
Mycobacterium tuberculosis Probable hydrolase 0.0063 0.0628 0.0957
Echinococcus granulosus retinal guanylyl cyclase 2 0.0348 0.4646 0.4645
Brugia malayi Protein kinase domain containing protein 0.0348 0.4646 0.7408
Trichomonas vaginalis TKL family protein kinase 0.0348 0.4646 0.8678
Trypanosoma brucei leucine-rich repeat protein (LRRP), putative 0.004 0.03 0.0398
Loa Loa (eye worm) TK/CSK protein kinase 0.0348 0.4646 0.7407
Trichomonas vaginalis leucine-rich transmembrane protein, putative 0.004 0.03 0.0513
Echinococcus multilocularis tyrosine protein kinase Blk 0.0348 0.4646 0.4645
Schistosoma mansoni shoc2 0.004 0.03 0.03
Brugia malayi CXXC zinc finger family protein 0.0051 0.0461 0.0735
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.03 0.0364
Brugia malayi Protein kinase domain containing protein 0.0348 0.4646 0.7408
Mycobacterium ulcerans aldehyde dehydrogenase 0.0053 0.0491 0.1216
Entamoeba histolytica leucine-rich repeat containing protein 0.004 0.03 0.0527
Echinococcus multilocularis c src tyrosine kinase 0.0348 0.4646 0.4645
Brugia malayi Guanylyl cyclase protein 23 0.0348 0.4646 0.7408
Entamoeba histolytica protein kinase domain containing protein 0.0348 0.4646 0.892
Echinococcus multilocularis heat shock protein 70 0.0348 0.4646 0.4645
Entamoeba histolytica hypothetical protein 0.0066 0.0665 0.1233
Trichomonas vaginalis TKL family protein kinase 0.0348 0.4646 0.8678
Echinococcus granulosus tyrosine protein kinase ABL1 0.0348 0.4646 0.4645
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0032 0.0197 0.033
Trichomonas vaginalis alpha-glucosidase, putative 0.0032 0.0197 0.0321
Brugia malayi Protein kinase domain containing protein 0.0348 0.4646 0.7408
Echinococcus granulosus epidermal growth factor receptor 0.0348 0.4646 0.4645
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0105 0.122 0.1945
Brugia malayi Protein kinase domain containing protein 0.0348 0.4646 0.7408
Echinococcus multilocularis chromobox protein 1 0.0054 0.0497 0.0495
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0348 0.4646 0.8678
Schistosoma mansoni hypothetical protein 0.0028 0.0138 0.0138
Loa Loa (eye worm) PDZ-domain-containing protein scribble 0.004 0.03 0.0474
Trichomonas vaginalis conserved hypothetical protein 0.0348 0.4646 0.8678
Leishmania major hypothetical protein, conserved 0.004 0.03 0.0364
Trichomonas vaginalis leucine-rich repeat-containing protein, putative 0.004 0.03 0.0513
Echinococcus multilocularis leucine rich repeat protein soc 2 0.004 0.03 0.0297
Schistosoma mansoni phd/f-box containing protein 0.0032 0.0197 0.0197
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0184 0.2333 0.3668
Schistosoma mansoni tyrosine kinase 0.0348 0.4646 0.4646
Trichomonas vaginalis TKL family protein kinase 0.0348 0.4646 0.8678
Echinococcus multilocularis DEAD box ATP dependent RNA helicase 0.004 0.03 0.0297
Loa Loa (eye worm) TK/FER protein kinase 0.0348 0.4646 0.7407
Trichomonas vaginalis conserved hypothetical protein 0.004 0.03 0.0513
Echinococcus multilocularis leucine rich repeats and immunoglobulin 0.004 0.03 0.0297
Leishmania major hypothetical protein, conserved 0.0063 0.0628 0.0802
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0552 0.7529 1
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0147 0.1819 0.3912
Plasmodium falciparum tyrosine kinase-like protein 0.0348 0.4646 1
Entamoeba histolytica leucine rich repeat / protein phosphatase 2C domain containing protein 0.004 0.03 0.0527
Entamoeba histolytica receptor protein kinase, putative 0.0348 0.4646 0.892
Onchocerca volvulus 0.0348 0.4646 0.8684
Trichomonas vaginalis TKL family protein kinase 0.0348 0.4646 0.8678
Brugia malayi Bromodomain containing protein 0.0056 0.0535 0.0853
Echinococcus granulosus integrin linked protein kinase 0.0348 0.4646 0.4645
Entamoeba histolytica tyrosine kinase, putative 0.0348 0.4646 0.892
Echinococcus multilocularis histone acetyltransferase MYST2 0.0095 0.1084 0.1082
Loa Loa (eye worm) hypothetical protein 0.0021 0.0041 0.0061
Loa Loa (eye worm) protein kinase domain-containing protein 0.0348 0.4646 0.7407
Brugia malayi jmjC domain containing protein 0.0238 0.3092 0.4931
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0032 0.0197 0.0364
Trichomonas vaginalis protein phosphatase 2C, putative 0.004 0.03 0.0513
Mycobacterium tuberculosis Conserved protein 0.0063 0.0628 0.0957
Onchocerca volvulus 0.0348 0.4646 0.8684
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0105 0.122 0.1591
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0348 0.4646 0.4645
Plasmodium falciparum thioredoxin reductase 0.0184 0.2333 0.5019
Entamoeba histolytica tyrosin kinase, putative 0.0348 0.4646 0.892
Toxoplasma gondii leucine-rich repeat protein LRR1 0.004 0.03 0.0645
Schistosoma mansoni protein phosphatase 2C 0.0032 0.0197 0.0197
Trypanosoma cruzi protein kinase, putative 0.0348 0.4646 0.6157
Trichomonas vaginalis TKL family protein kinase 0.0348 0.4646 0.8678
Loa Loa (eye worm) hypothetical protein 0.004 0.03 0.0474
Echinococcus multilocularis lysosomal alpha glucosidase 0.0146 0.18 0.1798
Loa Loa (eye worm) hypothetical protein 0.0056 0.0535 0.0849
Echinococcus granulosus tyrosine protein kinase csk 0.0348 0.4646 0.4645
Brugia malayi hypothetical protein 0.0415 0.5597 0.8924
Loa Loa (eye worm) hypothetical protein 0.0348 0.4646 0.7407
Trichomonas vaginalis TKL family protein kinase 0.0348 0.4646 0.8678
Echinococcus multilocularis protein KINase family member (kin 25) 0.0348 0.4646 0.4645
Schistosoma mansoni ephrin receptor 0.0348 0.4646 0.4646
Loa Loa (eye worm) jmjC domain-containing protein 0.0124 0.1493 0.2377
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0348 0.4646 0.4645
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0348 0.4646 0.4645
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0051 0.0456 0.1487
Loa Loa (eye worm) solute carrier family 6 member 4 0.0109 0.1285 0.2046
Onchocerca volvulus Peroxidasin homolog 0.004 0.03 0.0556
Toxoplasma gondii exonuclease III APE 0.002 0.0027 0.0058
Trichomonas vaginalis TKL family protein kinase 0.0348 0.4646 0.8678
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0032 0.0197 0.0227
Echinococcus granulosus leucine rich repeat containing protein 23 0.004 0.03 0.0297
Loa Loa (eye worm) beta-lactamase 0.0063 0.0628 0.0998
Trichomonas vaginalis glutathione reductase, putative 0.0064 0.0639 0.115
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0019 0.0003 0.0005
Trichomonas vaginalis D-aminoacylase, putative 0.0063 0.0628 0.113
Echinococcus granulosus leucine rich repeat containing protein 15 0.004 0.03 0.0297
Onchocerca volvulus 0.0084 0.092 0.1717
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0019 0.0003 0.0004
Entamoeba histolytica protein kinase, putative 0.0348 0.4646 0.892
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0028 0.0142 0.0216
Echinococcus granulosus jumonji domain containing 1A 0.0032 0.0197 0.0194
Brugia malayi chromobox protein homolog 3 0.003 0.0165 0.0263
Echinococcus granulosus tyrosine kinase 0.0348 0.4646 0.4645
Brugia malayi hypothetical protein 0.0019 0.0003 0.0004
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0225 0.2916 0.5428
Leishmania major hypothetical protein, conserved 0.0032 0.0197 0.0227
Trichomonas vaginalis conserved hypothetical protein 0.0348 0.4646 0.8678
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0348 0.4646 0.4645
Loa Loa (eye worm) hypothetical protein 0.0024 0.0073 0.0112
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0064 0.0639 0.1018
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0028 0.0138 0.0219
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0064 0.0639 0.0816
Schistosoma mansoni inositol monophosphatase 0.0028 0.0142 0.0142
Giardia lamblia PHD finger protein 15 0.0056 0.0535 0.11
Echinococcus granulosus tyrosine protein kinase Fyn 0.0348 0.4646 0.4645
Entamoeba histolytica protein kinase, putative 0.0348 0.4646 0.892
Echinococcus granulosus lysosomal alpha glucosidase 0.0146 0.18 0.1798
Schistosoma mansoni cpg binding protein 0.0054 0.0502 0.0502
Onchocerca volvulus 0.0063 0.0628 0.117
Trichomonas vaginalis toll, putative 0.004 0.03 0.0513
Treponema pallidum NADH oxidase 0.0064 0.0639 0.2118
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0333 0.4442 0.7082
Brugia malayi Leucine Rich Repeat family protein 0.004 0.03 0.0478
Echinococcus multilocularis phd:f box containing protein 0.0032 0.0197 0.0194
Loa Loa (eye worm) TK protein kinase 0.0348 0.4646 0.7407
Schistosoma mansoni tyrosine kinase 0.0348 0.4646 0.4646
Loa Loa (eye worm) hypothetical protein 0.004 0.03 0.0474
Echinococcus granulosus variable lymphocyte receptor 0.004 0.03 0.0297
Trypanosoma brucei hypothetical protein, conserved 0.004 0.03 0.0398
Schistosoma mansoni hypothetical protein 0.004 0.03 0.03
Giardia lamblia Kinase 0.0348 0.4646 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0027 0.0001
Echinococcus granulosus tyrosine protein kinase Lyn 0.0348 0.4646 0.4645
Entamoeba histolytica tyrosine kinase, putative 0.0348 0.4646 0.892
Onchocerca volvulus 0.004 0.03 0.0556
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0063 0.0628 0.0957
Plasmodium falciparum phd finger protein, putative 0.0056 0.0535 0.1146
Loa Loa (eye worm) TK protein kinase 0.0348 0.4646 0.7407
Giardia lamblia Hypothetical protein 0.004 0.03 0.0591
Plasmodium falciparum glutathione reductase 0.0184 0.2333 0.5019
Onchocerca volvulus 0.0348 0.4646 0.8684
Schistosoma mansoni sodium/chloride dependent transporter 0.0019 0.0003 0.0003
Brugia malayi Protein kinase domain containing protein 0.0348 0.4646 0.7408
Schistosoma mansoni hypothetical protein 0.004 0.03 0.03
Trichomonas vaginalis TKL family protein kinase 0.0348 0.4646 0.8678
Echinococcus granulosus Leucine rich repeat typical subtype 0.004 0.03 0.0297
Schistosoma mansoni serine/threonine protein kinase 0.0348 0.4646 0.4646
Schistosoma mansoni hypothetical protein 0.004 0.03 0.03
Loa Loa (eye worm) TK protein kinase 0.0348 0.4646 0.7407
Loa Loa (eye worm) serotonin transporter b 0.0109 0.1285 0.2046
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0028 0.0142 0.0641
Schistosoma mansoni phosphatidylserine receptor 0.0032 0.0197 0.0197
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0027 0.0001
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0064 0.0639 0.137
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0261 0.3426 0.4532
Entamoeba histolytica tyrosine kinase, putative 0.0348 0.4646 0.892
Loa Loa (eye worm) TK/FER protein kinase 0.0348 0.4646 0.7407
Trichomonas vaginalis TKL family protein kinase 0.0348 0.4646 0.8678
Trypanosoma cruzi leucine-rich repeat protein, putative 0.004 0.03 0.0364
Loa Loa (eye worm) hypothetical protein 0.0028 0.0138 0.0215
Trichomonas vaginalis leucine-rich repeat-containing protein, putative 0.004 0.03 0.0513
Echinococcus multilocularis leucine rich repeat containing protein 47 0.004 0.03 0.0297
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0019 0.0003 0.0004
Brugia malayi hypothetical protein 0.0348 0.4646 0.7408
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0348 0.4646 0.4645
Onchocerca volvulus 0.004 0.03 0.0556
Onchocerca volvulus 0.0063 0.0628 0.117
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0051 0.0461 0.0461
Echinococcus granulosus beta LACTamase domain containing family member 0.0063 0.0628 0.0626
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0333 0.4442 0.4442
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.03 0.0364
Trichomonas vaginalis TKL family protein kinase 0.0348 0.4646 0.8678
Echinococcus granulosus fibroblast growth factor receptor 4 0.0348 0.4646 0.4645
Loa Loa (eye worm) TK/FER protein kinase 0.0348 0.4646 0.7407
Echinococcus granulosus tyrosine kinase 0.0348 0.4646 0.4645
Mycobacterium ulcerans lipase LipD 0.0063 0.0628 0.1577
Trichomonas vaginalis conserved hypothetical protein 0.004 0.03 0.0513
Trypanosoma cruzi phopshatase, putative 0.004 0.03 0.0364
Schistosoma mansoni flightless-I 0.004 0.03 0.03
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0348 0.4646 0.892
Echinococcus granulosus peregrin 0.0056 0.0535 0.0532
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0064 0.0639 0.0848
Entamoeba histolytica protein kinase domain containing protein 0.0348 0.4646 0.892
Leishmania major dual specificity protein phosphatase, putative 0.004 0.03 0.0364
Schistosoma mansoni tyrosine kinase 0.0348 0.4646 0.4646
Brugia malayi Protein kinase domain containing protein 0.0348 0.4646 0.7408
Entamoeba histolytica leucine-rich repeat containing protein 0.004 0.03 0.0527
Trypanosoma cruzi leucine-rich repeat protein, putative 0.004 0.03 0.0364
Schistosoma mansoni inositol monophosphatase 0.0028 0.0142 0.0142
Schistosoma mansoni hypothetical protein 0.004 0.03 0.03
Loa Loa (eye worm) RGC/RGC protein kinase 0.0348 0.4646 0.7407
Echinococcus granulosus cell polarity protein 0.004 0.03 0.0297
Echinococcus granulosus chromobox protein 1 0.0054 0.0497 0.0495
Echinococcus multilocularis cpg binding protein 0.0054 0.0502 0.0499
Schistosoma mansoni variable lymphocyte receptor 0.004 0.03 0.03
Echinococcus granulosus leucine rich repeat protein 1 0.004 0.03 0.0297
Trichomonas vaginalis podocan, putative 0.004 0.03 0.0513
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0348 0.4646 0.4645
Brugia malayi Leucine Rich Repeat family protein 0.004 0.03 0.0478
Trypanosoma brucei leucine-rich repeat protein (LRRP), putative 0.004 0.03 0.0398
Brugia malayi C-terminal src kinase protein 1 0.0348 0.4646 0.7408
Plasmodium falciparum tyrosine kinase-like protein 0.0348 0.4646 1
Trichomonas vaginalis D-aminoacylase, putative 0.0063 0.0628 0.113
Echinococcus granulosus activated cdc42 kinase 1 0.0348 0.4646 0.4645
Echinococcus granulosus histone lysine methyltransferase setb 0.0051 0.0461 0.0459
Plasmodium vivax JmjC domain containing protein 0.0032 0.0197 0.0418
Echinococcus multilocularis chromobox protein 1 0.0054 0.0497 0.0495
Onchocerca volvulus 1D304 homolog 0.004 0.03 0.0556
Schistosoma mansoni ras suppressor protein 1 rsu1 0.004 0.03 0.03
Toxoplasma gondii PHD-finger domain-containing protein 0.0056 0.0535 0.1151
Entamoeba histolytica tyrosine kinase, putative 0.0348 0.4646 0.892
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0019 0.0003 0.0005
Plasmodium falciparum protein kinase, putative 0.0348 0.4646 1
Schistosoma mansoni leucine-rich repeat protein 0.004 0.03 0.03
Mycobacterium tuberculosis Probable esterase LipL 0.0063 0.0628 0.0957
Schistosoma mansoni jumonji/arid domain-containing protein 0.0124 0.1493 0.1493
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0027 0.0024
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0348 0.4646 0.4645
Schistosoma mansoni hypothetical protein 0.0551 0.7508 0.7508
Schistosoma mansoni tyrosine kinase 0.0348 0.4646 0.4646
Echinococcus multilocularis leucine rich repeat containing protein 0.004 0.03 0.0297
Schistosoma mansoni sodium-dependent amino acid transporter 0.0019 0.0003 0.0003
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0348 0.4646 0.892
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0348 0.4646 0.7407
Entamoeba histolytica protein kinase, putative 0.0348 0.4646 0.892
Trichomonas vaginalis chaoptin, putative 0.004 0.03 0.0513
Echinococcus granulosus insulin receptor 0.0348 0.4646 0.4645
Trichomonas vaginalis TKL family protein kinase 0.0348 0.4646 0.8678
Trypanosoma cruzi PAB1-binding protein , putative 0.0023 0.0059 0.0043
Trypanosoma cruzi Outer row dynein-assembly protein 7 0.004 0.03 0.0364
Entamoeba histolytica hypothetical protein 0.0387 0.5206 1
Entamoeba histolytica protein kinase domain containing protein 0.0348 0.4646 0.892
Brugia malayi Protein kinase domain containing protein 0.0348 0.4646 0.7408
Trichomonas vaginalis TKL family protein kinase 0.0348 0.4646 0.8678
Echinococcus granulosus peroxidasin 0.004 0.03 0.0297
Loa Loa (eye worm) inositol-1 0.0028 0.0142 0.0222
Entamoeba histolytica tyrosine kinase, putative 0.0348 0.4646 0.892
Schistosoma mansoni tyrosine kinase 0.0348 0.4646 0.4646
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0348 0.4646 0.4645
Schistosoma mansoni protein kinase 0.0348 0.4646 0.4646
Schistosoma mansoni protein kinase 0.0348 0.4646 0.4646
Plasmodium falciparum JmjC domain-containing protein, putative 0.0032 0.0197 0.0418
Loa Loa (eye worm) MH2 domain-containing protein 0.0099 0.1144 0.182
Leishmania major hypothetical protein, conserved 0.004 0.03 0.0364
Brugia malayi Leucine Rich Repeat family protein 0.004 0.03 0.0478
Onchocerca volvulus 0.0085 0.0935 0.1743
Loa Loa (eye worm) leucine Rich Repeat family protein 0.004 0.03 0.0474
Giardia lamblia Leucine-rich repeat protein 0.004 0.03 0.0591
Trypanosoma brucei leucine-rich repeat protein (LRRP), putative 0.004 0.03 0.0398
Schistosoma mansoni jumonji domain containing protein 0.0032 0.0197 0.0197
Echinococcus multilocularis survival motor neuron protein 1 0.0415 0.5597 0.5596
Loa Loa (eye worm) glutathione reductase 0.0184 0.2333 0.3717
Trichomonas vaginalis leucine-rich repeat containing protein, putative 0.004 0.03 0.0513
Entamoeba histolytica protein kinase domain containing protein 0.0348 0.4646 0.892
Echinococcus granulosus chromobox protein 1 0.0054 0.0497 0.0495
Loa Loa (eye worm) Ras-binding protein SUR-8 0.004 0.03 0.0474
Trichomonas vaginalis esterase, putative 0.0063 0.0628 0.113
Schistosoma mansoni tyrosine kinase 0.0348 0.4646 0.4646
Echinococcus granulosus tyrosine protein kinase Src64B 0.0348 0.4646 0.4645
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0165 0.0259
Brugia malayi Protein kinase domain containing protein 0.0348 0.4646 0.7408
Brugia malayi Protein kinase domain containing protein 0.0348 0.4646 0.7408
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0064 0.0639 0.0816
Entamoeba histolytica protein kinase, putative 0.0348 0.4646 0.892
Echinococcus multilocularis leucine rich repeat and fibronectin type III 0.004 0.03 0.0297
Trichomonas vaginalis protein phosphatases pp1 regulatory subunit, putative 0.004 0.03 0.0513
Entamoeba histolytica hypothetical protein 0.0348 0.4646 0.892
Loa Loa (eye worm) hypothetical protein 0.0032 0.0197 0.031
Schistosoma mansoni tyrosine kinase 0.0348 0.4646 0.4646
Echinococcus granulosus DEAD box ATP dependent RNA helicase 0.004 0.03 0.0297
Trichomonas vaginalis mercuric reductase, putative 0.0064 0.0639 0.115
Loa Loa (eye worm) CXXC zinc finger family protein 0.0051 0.0461 0.0731
Toxoplasma gondii hypothetical protein 0.0051 0.0456 0.0982
Echinococcus multilocularis insulin receptor 0.0348 0.4646 0.4645
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0348 0.4646 0.4645
Echinococcus granulosus Leucine rich repeat domain containing protein 0.004 0.03 0.0297
Loa Loa (eye worm) hypothetical protein 0.0348 0.4646 0.7407
Loa Loa (eye worm) TK/ACK protein kinase 0.0348 0.4646 0.7407
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0225 0.2916 0.5579
Trichomonas vaginalis TKL family protein kinase 0.0348 0.4646 0.8678
Trichomonas vaginalis leucine-rich repeat containing protein, putative 0.004 0.03 0.0513
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0041 0.0026
Echinococcus granulosus tyrosine protein kinase Src42A 0.0348 0.4646 0.4645
Toxoplasma gondii aldehyde dehydrogenase 0.0053 0.0491 0.1056
Echinococcus multilocularis SAM and MBT domain containing protein 0.0084 0.092 0.0918
Echinococcus granulosus epidermal growth factor receptor 0.0348 0.4646 0.4645
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0028 0.0142 0.0216
Entamoeba histolytica leucine rich repeat / protein phosphatase 2C domain containing protein 0.004 0.03 0.0527
Brugia malayi SH2 domain containing protein 0.0348 0.4646 0.7408
Loa Loa (eye worm) TK/RYK protein kinase 0.0348 0.4646 0.7407
Echinococcus multilocularis cell polarity protein leucine rich repeat 0.004 0.03 0.0297
Schistosoma mansoni serine/threonine protein kinase 0.0348 0.4646 0.4646
Mycobacterium tuberculosis Conserved protein 0.0063 0.0628 0.0957
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0064 0.0639 0.0816
Entamoeba histolytica hypothetical protein 0.0348 0.4646 0.892
Onchocerca volvulus 0.0348 0.4646 0.8684
Trichomonas vaginalis TKL family protein kinase 0.0348 0.4646 0.8678
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0105 0.122 0.3127
Plasmodium vivax protein phosphatases PP1 regulatory subunit sds22, putative 0.004 0.03 0.064
Brugia malayi Probable ClpP-like protease 0.0147 0.1819 0.29
Schistosoma mansoni hypothetical protein 0.004 0.03 0.03
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0041 0.0026
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0019 0.0003 0.0003
Schistosoma mansoni peroxidasin 0.004 0.03 0.03
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0348 0.4646 0.4645
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0064 0.0639 0.0816
Brugia malayi hypothetical protein 0.0023 0.0059 0.0094
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0019 0.0003 0.0004
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0348 0.4646 0.892
Loa Loa (eye worm) jmjC domain-containing protein 0.0032 0.0197 0.031
Brugia malayi Leucine Rich Repeat family protein 0.004 0.03 0.0478
Loa Loa (eye worm) hypothetical protein 0.0348 0.4646 0.7407
Trichomonas vaginalis protein phosphatase type 2C, putative 0.004 0.03 0.0513
Loa Loa (eye worm) jmjC domain-containing protein 0.0032 0.0197 0.031
Loa Loa (eye worm) leucine Rich Repeat family protein 0.004 0.03 0.0474
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0064 0.0639 0.1604
Schistosoma mansoni tyrosine protein kinase 0.0348 0.4646 0.4646
Echinococcus multilocularis protein flightless 1 0.004 0.03 0.0297
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0348 0.4646 0.4645
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0348 0.4646 0.4645
Entamoeba histolytica protein kinase, putative 0.0348 0.4646 0.892
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0064 0.0639 0.0973
Schistosoma mansoni shoc2 0.004 0.03 0.03
Treponema pallidum sodium- and chloride- dependent transporter 0.0109 0.1285 0.4354
Echinococcus multilocularis raf serine:threonine protein kinase 0.0348 0.4646 0.4645
Schistosoma mansoni tyrosine kinase 0.0348 0.4646 0.4646
Entamoeba histolytica serine/threonine kinase, putative 0.0348 0.4646 0.892
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.03 0.0364
Treponema pallidum fructose-bisphosphate aldolase 0.0225 0.2916 1
Plasmodium falciparum leucine-rich repeat protein 0.004 0.03 0.064
Trichomonas vaginalis TKL family protein kinase 0.0348 0.4646 0.8678
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0095 0.1075 0.1397
Trichomonas vaginalis STE family protein kinase 0.0348 0.4646 0.8678
Brugia malayi Glycosyl hydrolases family 31 protein 0.0032 0.0197 0.0315
Echinococcus multilocularis tyrosine protein kinase csk 0.0348 0.4646 0.4645
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0027 0.0001
Brugia malayi Pre-SET motif family protein 0.0051 0.0461 0.0735
Trypanosoma cruzi protein kinase, putative 0.0348 0.4646 0.6157
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0348 0.4646 0.8684
Echinococcus multilocularis tyrosine protein kinase Srms 0.0348 0.4646 0.4645
Brugia malayi Heterochromatin protein 1 0.0054 0.0497 0.0793
Trypanosoma cruzi kinatase, putative 0.004 0.03 0.0364
Trypanosoma cruzi hypothetical protein, conserved 0.0032 0.0197 0.0228
Leishmania major hypothetical protein, conserved 0.004 0.03 0.0364
Plasmodium vivax SET domain protein, putative 0.0051 0.0461 0.0987
Trichomonas vaginalis penicillin-binding protein, putative 0.0063 0.0628 0.113
Entamoeba histolytica tyrosine kinase, putative 0.0348 0.4646 0.892
Trichomonas vaginalis TKL family protein kinase 0.0348 0.4646 0.8678
Echinococcus granulosus tyrosine protein kinase Srms 0.0348 0.4646 0.4645
Schistosoma mansoni jumonji domain containing protein 0.02 0.2558 0.2558
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0066 0.0665 0.0663
Echinococcus granulosus leucine rich repeat and death domain containing protein 0.004 0.03 0.0297
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0027 0.0052
Leishmania major proteophosphoglycan ppg3, putative 0.004 0.03 0.0364
Brugia malayi PHD-finger family protein 0.0021 0.0041 0.0065
Trichomonas vaginalis TKL family protein kinase 0.0348 0.4646 0.8678
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0048 0.0419 0.0417
Echinococcus multilocularis epidermal growth factor receptor 0.0348 0.4646 0.4645
Loa Loa (eye worm) hypothetical protein 0.004 0.03 0.0474
Schistosoma mansoni protein kinase 0.0348 0.4646 0.4646
Schistosoma mansoni tyrosine kinase 0.0348 0.4646 0.4646
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0348 0.4646 0.4645
Trichomonas vaginalis TKL family protein kinase 0.0348 0.4646 0.8678
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0109 0.1285 0.2049
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.011 0.1292 0.2012
Loa Loa (eye worm) TK/FER protein kinase 0.0348 0.4646 0.7407
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0348 0.4646 0.4646
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.035 0.4671 0.7447
Entamoeba histolytica tyrosine kinase, putative 0.0348 0.4646 0.892
Plasmodium vivax hypothetical protein, conserved 0.0022 0.0044 0.0089
Trichomonas vaginalis TKL family protein kinase 0.0348 0.4646 0.8678
Trypanosoma brucei protein phosphatase 1, regulatory subunit, putative 0.004 0.03 0.0398
Loa Loa (eye worm) hypothetical protein 0.004 0.03 0.0474
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.004 0.03 0.0474
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0348 0.4646 0.4645
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.011 0.1292 0.1918
Onchocerca volvulus 0.004 0.03 0.0556
Loa Loa (eye worm) TK/FER protein kinase 0.0348 0.4646 0.7407
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.006 0.0585 0.0585
Echinococcus granulosus leucine rich repeat containing protein 24 0.004 0.03 0.0297
Echinococcus multilocularis leucine rich repeat protein SHOC 2 0.004 0.03 0.0297
Brugia malayi jmjC domain containing protein 0.0032 0.0197 0.0314
Brugia malayi hypothetical protein 0.004 0.03 0.0478
Loa Loa (eye worm) hypothetical protein 0.0095 0.1084 0.1725
Trypanosoma brucei dual specificity protein phosphatase, putative 0.004 0.03 0.0398
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0027 0.0039
Leishmania major mitochondrial DNA polymerase beta 0.0552 0.7529 1
Echinococcus multilocularis integrin linked protein kinase 0.0348 0.4646 0.4645
Trichomonas vaginalis TKL family protein kinase 0.0348 0.4646 0.8678
Echinococcus granulosus jumonji domain containing protein 0.0078 0.0846 0.0844
Trypanosoma brucei protein kinase, putative 0.0348 0.4646 0.6171
Schistosoma mansoni mixed-lineage leukemia protein mll 0.011 0.1294 0.1294
Brugia malayi EGF-like domain containing protein 0.004 0.03 0.0478
Echinococcus granulosus leucine rich repeat containing protein 57 0.004 0.03 0.0297
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0053 0.0491 0.0488
Schistosoma mansoni alpha glucosidase 0.0032 0.0197 0.0197
Echinococcus multilocularis ephrin type A receptor 4 A 0.0348 0.4646 0.4645

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 104 nM Inhibition of [3H]-dopamine uptake in rat caudate putamen tissue. ChEMBL. 10479283
Ki (binding) = 27 nM Displacement of [3H]-WIN- 35,428 binding to the dopamine transporter in rat caudate putamen tissue. ChEMBL. 10479283

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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