Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Animal haem peroxidase family protein | 0.0281 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0281 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0281 | 0.5 | 0.5 |
Onchocerca volvulus | Peroxidase homolog | 0.0281 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0281 | 0.5 | 0.5 |
Brugia malayi | Animal haem peroxidase family protein | 0.0281 | 0.5 | 0.5 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0281 | 0.5 | 0.5 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0281 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0281 | 0.5 | 0.5 |
Onchocerca volvulus | Dual oxidase homolog | 0.0281 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0281 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0281 | 0.5 | 0.5 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0281 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0281 | 0.5 | 0.5 |
Onchocerca volvulus | Peroxidasin homolog | 0.0281 | 0.5 | 0.5 |
Onchocerca volvulus | 0.0281 | 0.5 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0281 | 0.5 | 0.5 |
Onchocerca volvulus | Peroxidasin homolog | 0.0281 | 0.5 | 0.5 |
Echinococcus multilocularis | peroxidasin | 0.0281 | 0.5 | 0.5 |
Schistosoma mansoni | peroxidasin | 0.0281 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0281 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0281 | 0.5 | 0.5 |
Brugia malayi | Animal haem peroxidase family protein | 0.0281 | 0.5 | 0.5 |
Schistosoma mansoni | peroxidasin | 0.0281 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0281 | 0.5 | 0.5 |
Onchocerca volvulus | 0.0281 | 0.5 | 0.5 | |
Brugia malayi | Animal haem peroxidase family protein | 0.0281 | 0.5 | 0.5 |
Onchocerca volvulus | Chorion peroxidase homolog | 0.0281 | 0.5 | 0.5 |
Onchocerca volvulus | 0.0281 | 0.5 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0281 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0281 | 0.5 | 0.5 |
Brugia malayi | Blistered cuticle protein 3 | 0.0281 | 0.5 | 0.5 |
Brugia malayi | Peroxidasin | 0.0281 | 0.5 | 0.5 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0281 | 0.5 | 0.5 |
Echinococcus granulosus | peroxidasin | 0.0281 | 0.5 | 0.5 |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.0281 | 0.5 | 0.5 |
Onchocerca volvulus | Peroxidase homolog | 0.0281 | 0.5 | 0.5 |
Brugia malayi | Animal haem peroxidase family protein | 0.0281 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0281 | 0.5 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Reduction (functional) | = 5 % | % Reduction of plasma triglyceride in the rat was measured at dose 37.5 mg/kg/d | ChEMBL. | 9733484 |
Reduction (functional) | = 16 % | % Reduction of plasma triglyceride in the rat was measured at dose 75 mg/kg/d | ChEMBL. | 9733484 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.