Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | CMGC family protein kinase | 0.0022 | 0.0125 | 0.5 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0022 | 0.0125 | 0.0125 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0022 | 0.0125 | 0.0125 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0022 | 0.0125 | 0.5 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0022 | 0.0125 | 0.5 |
Trypanosoma brucei | protein kinase, putative | 0.0022 | 0.0125 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0022 | 0.0125 | 0.5 |
Onchocerca volvulus | Bile acid receptor homolog | 0.002 | 0 | 0.5 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0022 | 0.0125 | 0.0149 |
Schistosoma mansoni | thyroid hormone receptor | 0.0146 | 1 | 1 |
Onchocerca volvulus | 0.002 | 0 | 0.5 | |
Trichomonas vaginalis | CMGC family protein kinase | 0.0022 | 0.0125 | 0.5 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0022 | 0.0125 | 0.5 |
Giardia lamblia | Kinase, CMGC MAPK | 0.0022 | 0.0125 | 0.5 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0022 | 0.0125 | 1 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0022 | 0.0125 | 0.0125 |
Brugia malayi | MAP kinase sur-1 | 0.0022 | 0.0125 | 1 |
Echinococcus granulosus | mitogen activated protein kinase | 0.0022 | 0.0125 | 0.0149 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0125 | 0.8387 | 0.8387 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0022 | 0.0125 | 0.5 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0022 | 0.0125 | 0.5 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.002 | 0 | 0.5 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0022 | 0.0125 | 0.5 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0022 | 0.0125 | 0.5 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0125 | 0.8387 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0125 | 0.8387 | 0.8387 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0022 | 0.0125 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0022 | 0.0125 | 0.5 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.002 | 0 | 0.5 |
Schistosoma mansoni | thyroid hormone receptor | 0.0146 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.