Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | RNA binding protein | 0.0146 | 0.7652 | 1 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0146 | 0.7652 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.003 | 0.0835 | 0.0835 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.003 | 0.0835 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0019 | 0.0185 | 0.0185 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.003 | 0.0835 | 0.1091 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0835 | 0.1091 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.003 | 0.0835 | 0.1091 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.003 | 0.0835 | 0.1091 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0019 | 0.0185 | 0.0185 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.003 | 0.0835 | 0.0835 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.003 | 0.0835 | 0.1091 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.003 | 0.0835 | 0.1091 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0105 | 0.5265 | 0.5265 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.003 | 0.0835 | 0.0835 |
Echinococcus granulosus | GPCR family 2 | 0.0019 | 0.0185 | 0.0185 |
Schistosoma mansoni | hypothetical protein | 0.0019 | 0.0185 | 0.0185 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.003 | 0.0835 | 0.0835 |
Brugia malayi | TAR-binding protein | 0.0146 | 0.7652 | 1 |
Echinococcus multilocularis | geminin | 0.0186 | 1 | 1 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.003 | 0.0835 | 0.0835 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.003 | 0.0835 | 0.1091 |
Schistosoma mansoni | hypothetical protein | 0.0186 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0019 | 0.0185 | 0.0185 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.003 | 0.0835 | 0.0835 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.2606 | 0.3405 |
Schistosoma mansoni | hypothetical protein | 0.0186 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.003 | 0.0835 | 0.1091 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.003 | 0.0835 | 0.1091 |
Schistosoma mansoni | thyroid hormone receptor | 0.003 | 0.0835 | 0.0835 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0105 | 0.5265 | 0.5265 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.003 | 0.0835 | 0.0835 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0105 | 0.5265 | 0.5265 |
Onchocerca volvulus | 0.003 | 0.0835 | 0.5 | |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.003 | 0.0835 | 0.0835 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.003 | 0.0835 | 0.1091 |
Echinococcus multilocularis | tar DNA binding protein | 0.0146 | 0.7652 | 0.7652 |
Brugia malayi | nuclear receptor NHR-88 | 0.003 | 0.0835 | 0.1091 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.003 | 0.0835 | 0.0835 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0105 | 0.5265 | 0.5265 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0105 | 0.5265 | 0.5265 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.003 | 0.0835 | 0.0835 |
Loa Loa (eye worm) | steroid hormone receptor | 0.003 | 0.0835 | 0.1091 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.003 | 0.0835 | 0.0835 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.003 | 0.0835 | 0.1091 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0131 | 0.6769 | 0.8847 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.003 | 0.0835 | 0.0835 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.003 | 0.0835 | 0.1091 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0835 | 0.1091 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.003 | 0.0835 | 0.1091 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0019 | 0.0185 | 0.0242 |
Schistosoma mansoni | tar DNA-binding protein | 0.0146 | 0.7652 | 0.7652 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.003 | 0.0835 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0019 | 0.0185 | 0.0185 |
Schistosoma mansoni | tar DNA-binding protein | 0.0146 | 0.7652 | 0.7652 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.1485 | 0.1941 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.006 | 0.2606 | 0.3405 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0105 | 0.5265 | 0.6881 |
Schistosoma mansoni | thyroid hormone receptor | 0.003 | 0.0835 | 0.0835 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.1485 | 0.1485 |
Onchocerca volvulus | Bile acid receptor homolog | 0.003 | 0.0835 | 0.5 |
Echinococcus granulosus | FTZ F1 alpha | 0.003 | 0.0835 | 0.0835 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.003 | 0.0835 | 0.1091 |
Echinococcus multilocularis | GPCR, family 2 | 0.0019 | 0.0185 | 0.0185 |
Echinococcus granulosus | tar DNA binding protein | 0.0146 | 0.7652 | 0.7652 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0835 | 0.1091 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0835 | 0.1091 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.003 | 0.0835 | 0.0835 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.003 | 0.0835 | 0.0835 |
Loa Loa (eye worm) | RNA binding protein | 0.0146 | 0.7652 | 1 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.003 | 0.0835 | 0.0835 |
Brugia malayi | steroid hormone receptor | 0.003 | 0.0835 | 0.1091 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.003 | 0.0835 | 0.1091 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.003 | 0.0835 | 0.1091 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0131 | 0.6769 | 0.8847 |
Echinococcus multilocularis | FTZ F1 alpha | 0.003 | 0.0835 | 0.0835 |
Brugia malayi | ecdysteroid receptor | 0.003 | 0.0835 | 0.1091 |
Brugia malayi | MH2 domain containing protein | 0.0131 | 0.6769 | 0.8847 |
Schistosoma mansoni | tar DNA-binding protein | 0.0146 | 0.7652 | 0.7652 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.003 | 0.0835 | 0.1091 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.003 | 0.0835 | 0.1091 |
Schistosoma mansoni | tar DNA-binding protein | 0.0146 | 0.7652 | 0.7652 |
Schistosoma mansoni | nuclear hormone receptor | 0.003 | 0.0835 | 0.0835 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0835 | 0.1091 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0019 | 0.0185 | 0.0185 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.003 | 0.0835 | 0.1091 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.003 | 0.0835 | 0.1091 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.006 | 0.2606 | 0.3405 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.003 | 0.0835 | 0.1091 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0105 | 0.5265 | 0.6881 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0019 | 0.0185 | 0.0185 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0019 | 0.0185 | 0.0242 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.003 | 0.0835 | 0.0835 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0041 | 0.1485 | 0.1941 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0835 | 0.1091 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.003 | 0.0835 | 0.1091 |
Schistosoma mansoni | coup transcription factor | 0.003 | 0.0835 | 0.0835 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.006 | 0.2606 | 0.3405 |
Loa Loa (eye worm) | TAR-binding protein | 0.0146 | 0.7652 | 1 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.003 | 0.0835 | 0.1091 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0835 | 0.1091 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.003 | 0.0835 | 0.0835 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0146 | 0.7652 | 1 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0019 | 0.0185 | 0.0185 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.003 | 0.0835 | 0.0835 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.003 | 0.0835 | 0.0835 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0105 | 0.5265 | 0.5265 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0835 | 0.1091 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.003 | 0.0835 | 0.1091 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.003 | 0.0835 | 0.0835 |
Schistosoma mansoni | tar DNA-binding protein | 0.0146 | 0.7652 | 0.7652 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0105 | 0.5265 | 0.5265 |
Brugia malayi | nuclear hormone receptor | 0.003 | 0.0835 | 0.1091 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.003 | 0.0835 | 0.0835 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0019 | 0.0185 | 0.0242 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.003 | 0.0835 | 0.0835 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.003 | 0.0835 | 0.0835 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.003 | 0.0835 | 0.0835 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0185 | 0.0242 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.003 | 0.0835 | 0.0835 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.