Detailed information for compound 2069260

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 379.403 | Formula: C18H18FNO5S
  • H donors: 1 H acceptors: 3 LogP: 2.73 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(NS(=O)(=O)c1ccc2c(c1)OCCCO2)CCc1ccccc1F
  • InChi: 1S/C18H18FNO5S/c19-15-5-2-1-4-13(15)6-9-18(21)20-26(22,23)14-7-8-16-17(12-14)25-11-3-10-24-16/h1-2,4-5,7-8,12H,3,6,9-11H2,(H,20,21)
  • InChiKey: QKDACQYRKLATMZ-UHFFFAOYSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.003 0.0071 0.007
Toxoplasma gondii NADPH-glutathione reductase 0.0016 0.0031 0.019
Plasmodium vivax inositol polyphosphate kinase, putative 0.0007 0.0003 0.0011
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0021 0.0046 0.0087
Loa Loa (eye worm) hypothetical protein 0.0035 0.0089 0.0132
Schistosoma mansoni amine GPCR 0.0035 0.0089 0.0104
Schistosoma mansoni voltage-gated ion channel 0.003 0.0071 0.0082
Echinococcus granulosus inositol trisphosphate 3 kinase C 0.0007 0.0003 0.0007
Plasmodium vivax protein kinase Crk2 0.0019 0.0038 0.0247
Echinococcus multilocularis G-protein coupled receptor, putative 0.0035 0.0089 0.0207
Loa Loa (eye worm) 6-phosphogluconolactonase 0.0131 0.038 0.0569
Schistosoma mansoni transient receptor potential channel 0.003 0.0071 0.0082
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.003 0.0071 0.007
Trichomonas vaginalis mannosyltransferase 1, putative 0.0311 0.0927 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0013 0.002 0.0186
Loa Loa (eye worm) hypothetical protein 0.0035 0.0089 0.0132
Echinococcus multilocularis rhodopsin orphan GPCR 0.0035 0.0089 0.0207
Giardia lamblia Kinase, AGC PKA 0.0007 0.0001 0.0015
Loa Loa (eye worm) hypothetical protein 0.003 0.0071 0.0105
Echinococcus multilocularis calcium activated potassium channel 0.003 0.0072 0.0169
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.003 0.0071 0.0165
Schistosoma mansoni voltage-gated potassium channel 0.003 0.0071 0.0082
Echinococcus multilocularis potassium voltage gated channel protein 0.003 0.0071 0.0165
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.003 0.0071 0.007
Echinococcus multilocularis dro:myosuppressin receptor 0.0035 0.0089 0.0207
Onchocerca volvulus 0.0035 0.0089 0.0931
Trichomonas vaginalis AGC family protein kinase 0.0023 0.0052 0.0535
Echinococcus granulosus 7TM GPCR rhodopsin 0.0035 0.0089 0.0207
Loa Loa (eye worm) beta-1,4-galactosyltransferase VII 0.0041 0.0106 0.0158
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0048 0.0126 0.3693
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0021 0.0046 0.0125
Brugia malayi Cytohesin 3 0.0132 0.0384 0.0383
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.003 0.0071 0.007
Brugia malayi hypothetical protein 0.0035 0.0089 0.0088
Brugia malayi inositol polyphosphate 6-/3-/5-kinase 2b 0.0007 0.0003 0.0002
Toxoplasma gondii fructose-bisphosphate aldolase, putative 0.0494 0.1486 1
Loa Loa (eye worm) TYRA-2 protein 0.0035 0.0089 0.0132
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0035 0.0089 0.0104
Onchocerca volvulus 0.0035 0.0089 0.0931
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.003 0.0071 0.0735
Onchocerca volvulus 0.0103 0.0296 0.3167
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.003 0.0071 0.0165
Echinococcus multilocularis transient receptor potential cation channel 0.003 0.0071 0.0165
Brugia malayi MIR domain containing protein 0.0311 0.0927 0.0926
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0023 0.0052 0.0076
Loa Loa (eye worm) hypothetical protein 0.0035 0.0089 0.0132
Schistosoma mansoni hypothetical protein 0.0024 0.0055 0.0063
Trichomonas vaginalis AGC family protein kinase 0.0015 0.0028 0.0273
Brugia malayi G protein-coupled receptor F59B2.13 0.0035 0.0089 0.0088
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0043 0.0113 0.0169
Echinococcus multilocularis voltage dependent calcium channel 0.003 0.0071 0.0165
Schistosoma mansoni histamine h1 receptor 0.0035 0.0089 0.0104
Echinococcus multilocularis fructose 1,6 bisphosphate aldolase 0.0494 0.1486 0.3458
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0016 0.0031 0.5
Giardia lamblia Kinase, CMGC CDK 0.0019 0.0038 0.3849
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0035 0.0089 0.0104
Leishmania major hypothetical protein, unknown function 0.003 0.0071 0.0198
Loa Loa (eye worm) phosphatidylinositol-specific phospholipase C 0.01 0.0287 0.043
Echinococcus granulosus serine threonine protein kinase nrc 0.0007 0.0001 0.0003
Plasmodium falciparum thioredoxin reductase 0.0048 0.0126 0.0838
Trichomonas vaginalis 1-phosphatidylinositol phosphodiesterase, putative 0.0015 0.0027 0.0265
Echinococcus multilocularis voltage gated hydrogen channel 1 0.003 0.0071 0.0165
Echinococcus granulosus voltage dependent calcium channel 0.003 0.0071 0.0165
Trypanosoma brucei 6-phosphogluconolactonase 0.0131 0.038 0.0744
Echinococcus granulosus allatostatin A receptor 0.0035 0.0089 0.0207
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0035 0.0089 0.0207
Brugia malayi 6-phosphogluconolactonase family protein 0.0131 0.038 0.0379
Toxoplasma gondii phosphoinositide phospholipase PIPLC 0.0083 0.0233 0.1551
Schistosoma mansoni myosin xvIII 0.0035 0.0089 0.0104
Loa Loa (eye worm) hypothetical protein 0.0035 0.0089 0.0132
Echinococcus multilocularis shaker cognate 0.003 0.0071 0.0165
Trypanosoma cruzi inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0119 0.0344 0.0676
Brugia malayi hypothetical protein 0.0035 0.0089 0.0088
Brugia malayi Phosphatidylinositol-specific phospholipase C, X domain containing protein 0.0036 0.009 0.0089
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0035 0.0089 0.0104
Echinococcus multilocularis TRP (transient receptor potential) channel 0.003 0.0071 0.0165
Schistosoma mansoni calcium-activated potassium channel 0.003 0.0071 0.0082
Plasmodium vivax glucose-6-phosphate 1-dehydrogenase, putative 0.0038 0.0097 0.0644
Mycobacterium tuberculosis Probable 6-phosphogluconolactonase DevB (6PGL) 0.0093 0.0264 0.9095
Trichomonas vaginalis AGC family protein kinase 0.0015 0.0028 0.0273
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0016 0.0146
Loa Loa (eye worm) hypothetical protein 0.0035 0.0089 0.0132
Trypanosoma cruzi 6-phosphogluconolactonase, putative 0.0131 0.038 0.0747
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0035 0.0089 0.0088
Echinococcus granulosus serotonin receptor 0.0035 0.0089 0.0207
Trypanosoma cruzi trypanothione reductase, putative 0.0048 0.0126 0.0245
Echinococcus granulosus high affinity choline transporter 1 0.0132 0.0383 0.089
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0016 0.0031 0.0201
Echinococcus granulosus neuropeptide receptor 0.0035 0.0089 0.0207
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.003 0.0071 0.0165
Brugia malayi fructose-bisphosphate aldolase 2 0.0494 0.1486 0.1485
Echinococcus granulosus potassium voltage gated channel protein 0.003 0.0071 0.0165
Loa Loa (eye worm) G-protein coupled receptor 0.0035 0.0089 0.0132
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0035 0.0089 0.0207
Echinococcus granulosus rhodopsin orphan GPCR 0.0035 0.0089 0.0207
Schistosoma mansoni 6-phosphogluconolactonase 0.0131 0.038 0.0456
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0023 0.0052 0.0121
Echinococcus multilocularis rhodopsin orphan GPCR 0.0035 0.0089 0.0207
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0007 0.0003 0.0007
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0012 0.0018 0.0017
Echinococcus multilocularis g protein coupled receptor 0.0035 0.0089 0.0207
Loa Loa (eye worm) hypothetical protein 0.0035 0.0089 0.0132
Trypanosoma brucei inositol hexakisphosphate kinase 0.0007 0.0003 0.0001
Schistosoma mansoni voltage-gated potassium channel 0.003 0.0071 0.0082
Trichomonas vaginalis PIKK family atypical protein kinase 0.0007 0.0003 0.0003
Mycobacterium ulcerans 6-phosphogluconolactonase 0.0131 0.038 1
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0035 0.0089 0.0104
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0031 0.0059
Brugia malayi Serotonin receptor 0.0035 0.0089 0.0088
Trypanosoma brucei phosphoinositide-specific phospholipase C 0.0056 0.0151 0.0291
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0016 0.0031 0.0083
Schistosoma mansoni biogenic amine receptor 0.0035 0.0089 0.0104
Leishmania major glucosamine-6-phosphate isomerase, putative 0.0038 0.0097 0.0274
Echinococcus granulosus voltage gated hydrogen channel 1 0.003 0.0071 0.0165
Echinococcus multilocularis fructose 1,6 bisphosphate aldolase 0.0494 0.1486 0.3458
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0035 0.0089 0.0088
Echinococcus granulosus potassium voltage gated channel subfamily D 0.003 0.0071 0.0165
Trypanosoma cruzi target of rapamycin kinase 3 0.0017 0.0033 0.0062
Brugia malayi hypothetical protein 0.0035 0.0089 0.0088
Toxoplasma gondii target of rapamycin (TOR), putative 0.0016 0.0029 0.0176
Schistosoma mansoni amine GPCR 0.0035 0.0089 0.0104
Echinococcus granulosus alpha 1A adrenergic receptor 0.0035 0.0089 0.0207
Echinococcus granulosus transient receptor potential cation channel 0.003 0.0071 0.0165
Echinococcus granulosus hypothetical protein 0.0035 0.0089 0.0207
Trypanosoma cruzi inositol polyphosphate kinase-like protein, putative 0.0007 0.0003 0.0003
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0035 0.0089 0.0104
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0007 0.0003 0.0002
Echinococcus granulosus g protein coupled receptor 0.0035 0.0089 0.0207
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0035 0.0089 0.0207
Loa Loa (eye worm) hypothetical protein 0.003 0.0071 0.0105
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.003 0.0071 0.007
Brugia malayi phospholipase C homolog 0.0023 0.0051 0.0049
Echinococcus granulosus sodium:glucose cotransporter 0.0517 0.1554 0.3616
Trichomonas vaginalis AGC family protein kinase 0.0015 0.0028 0.0273
Trichomonas vaginalis CMGC family protein kinase 0.0019 0.0038 0.0385
Loa Loa (eye worm) hypothetical protein 0.0035 0.0089 0.0132
Trypanosoma cruzi trypanothione reductase, putative 0.0016 0.0031 0.0059
Brugia malayi Protein kinase domain containing protein 0.0023 0.0052 0.0051
Brugia malayi larval opioid receptor 0.0035 0.0089 0.0088
Echinococcus multilocularis Metazoa galactosyltransferase 0.0157 0.0458 0.1065
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0035 0.0089 0.0207
Loa Loa (eye worm) hypothetical protein 0.0035 0.0089 0.0132
Echinococcus granulosus potassium large conductance calcium activated 0.003 0.0071 0.0165
Echinococcus multilocularis inositol trisphosphate 3 kinase C 0.0007 0.0003 0.0007
Giardia lamblia Inositol hexakisphosphate kinase 0.0007 0.0003 0.0189
Echinococcus multilocularis serotonin receptor 0.0035 0.0089 0.0207
Trichomonas vaginalis 1-phosphatidylinositol phosphodiesterase, putative 0.0015 0.0027 0.0265
Trypanosoma cruzi 6-phosphogluconolactonase, putative 0.0131 0.038 0.0747
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0035 0.0089 0.0132
Brugia malayi ORL1-like opioid receptor 0.0035 0.0089 0.0088
Trypanosoma cruzi CYC2-like cyclin 4, putative 0.0011 0.0015 0.0027
Trichomonas vaginalis PIKK family atypical protein kinase 0.0007 0.0003 0.0003
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0035 0.0089 0.0207
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0016 0.0031 0.0073
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0038 0.0043
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.003 0.0071 0.0165
Toxoplasma gondii hypothetical protein 0.0041 0.0106 0.0696
Echinococcus multilocularis cyclin dependent kinase 0.0019 0.0038 0.0089
Entamoeba histolytica protein kinase, putative 0.0015 0.0028 0.0285
Plasmodium vivax hypothetical protein, conserved 0.0007 0.0003 0.0011
Schistosoma mansoni beta-14-galactosyltransferase 0.0041 0.0106 0.0125
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0035 0.0089 0.0207
Trypanosoma cruzi inositol polyphosphate kinase, putative 0.0007 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0119 0.0344 0.0515
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.003 0.0071 0.0165
Brugia malayi olfactory channel protein osm-9 0.003 0.0071 0.007
Echinococcus granulosus hyperpolarization activated cyclic 0.003 0.0071 0.0165
Brugia malayi Dopamine receptor 0.0035 0.0089 0.0088
Echinococcus granulosus potassium voltage gated channel subfamily C 0.003 0.0071 0.0165
Schistosoma mansoni voltage-gated potassium channel 0.003 0.0071 0.0082
Schistosoma mansoni opsin-like receptor 0.0035 0.0089 0.0104
Loa Loa (eye worm) hypothetical protein 0.1873 0.5684 0.8546
Schistosoma mansoni alpha-1 adrenergic receptor 0.0035 0.0089 0.0104
Schistosoma mansoni opsin-like receptor 0.0035 0.0089 0.0104
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0009 0.0008 0.001
Loa Loa (eye worm) hypothetical protein 0.0035 0.0089 0.0132
Loa Loa (eye worm) hypothetical protein 0.0035 0.0089 0.0132
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0019 0.0038 0.0103
Brugia malayi hypothetical protein 0.0035 0.0089 0.0088
Trypanosoma cruzi cdc2-related kinase 1 0.0019 0.0038 0.0072
Toxoplasma gondii fructose-1,6-bisphosphate aldolase 0.0494 0.1486 1
Entamoeba histolytica inositol polyphosphate kinase, putative 0.0007 0.0003 0.0018
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.003 0.0071 0.0165
Loa Loa (eye worm) hypothetical protein 0.0035 0.0089 0.0132
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0038 0.0097 0.1022
Brugia malayi phospholipase C homolog 0.0063 0.0172 0.0171
Trypanosoma cruzi cdc2-related kinase 1 0.0019 0.0038 0.0072
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0031 0.0059
Echinococcus multilocularis rhodopsin orphan GPCR 0.0035 0.0089 0.0207
Echinococcus granulosus fructose bisphosphate aldolase class I 0.0494 0.1486 0.3458
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0021 0.0046 0.0125
Echinococcus multilocularis rhodopsin orphan GPCR 0.0035 0.0089 0.0207
Echinococcus granulosus cyclic nucleotide gated cation channel 0.003 0.0071 0.0165
Brugia malayi follicle stimulating hormone receptor 0.0035 0.0089 0.0088
Echinococcus multilocularis somatostatin receptor 0.0035 0.0089 0.0207
Echinococcus granulosus rhodopsin orphan GPCR 0.0035 0.0089 0.0207
Plasmodium vivax fructose 1,6-bisphosphate aldolase, putative 0.0494 0.1486 1
Echinococcus granulosus somatostatin receptor 0.0035 0.0089 0.0207
Trichomonas vaginalis AGC family protein kinase 0.0015 0.0028 0.0273
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.003 0.0071 0.0082
Brugia malayi GnHR receptor homolog 0.0035 0.0089 0.0088
Loa Loa (eye worm) hypothetical protein 0.003 0.0071 0.0105
Schistosoma mansoni neuropeptide receptor 0.0035 0.0089 0.0104
Loa Loa (eye worm) neuropeptide F receptor 0.0035 0.0089 0.0132
Echinococcus granulosus 1-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-4 0.0086 0.0242 0.0563
Brugia malayi GH02984p 0.0132 0.0383 0.0381
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0035 0.0089 0.0132
Trypanosoma cruzi fructose-bisphosphate aldolase, glycosomal, putative 0.0494 0.1486 0.2928
Echinococcus multilocularis neuropeptides capa receptor 0.0035 0.0089 0.0207
Schistosoma mansoni biogenic amine receptor 0.0035 0.0089 0.0104
Giardia lamblia Glucosamine-6-phosphate deaminase 0.0038 0.0097 1
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0019 0.0038 0.0103
Brugia malayi Sodium:solute symporter family protein 0.0132 0.0383 0.0381
Loa Loa (eye worm) hypothetical protein 0.0035 0.0089 0.0132
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0035 0.0089 0.0207
Echinococcus granulosus TRP transient receptor potential channel 0.003 0.0071 0.0165
Loa Loa (eye worm) hypothetical protein 0.003 0.0071 0.0105
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0033 0.0325
Brugia malayi 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 4 0.0083 0.0235 0.0234
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.003 0.0071 0.0082
Loa Loa (eye worm) hypothetical protein 0.0086 0.0242 0.0362
Echinococcus multilocularis rhodopsin orphan GPCR 0.0035 0.0089 0.0207
Echinococcus granulosus potassium voltage gated channel subfamily H 0.003 0.0071 0.0165
Loa Loa (eye worm) hypothetical protein 0.0132 0.0383 0.0573
Loa Loa (eye worm) hypothetical protein 0.0035 0.0089 0.0132
Echinococcus granulosus tm gpcr rhodopsin 0.0035 0.0089 0.0207
Schistosoma mansoni voltage-gated potassium channel 0.003 0.0071 0.0082
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.003 0.0071 0.0458
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0035 0.0089 0.0104
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0031 0.0059
Schistosoma mansoni stromal cell-derived factor 2 precursor-like protein 0.0311 0.0927 0.1116
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.003 0.0071 0.0165
Echinococcus multilocularis fructose 1,6 bisphosphate aldolase 0.0494 0.1486 0.3458
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.1672 0.5071 1
Echinococcus multilocularis g protein coupled receptor 0.0035 0.0089 0.0207
Echinococcus granulosus transient receptor potential cation channel 0.003 0.0071 0.0165
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0016 0.0031 0.0201
Loa Loa (eye worm) hypothetical protein 0.0035 0.0089 0.0132
Echinococcus granulosus rhodopsin orphan GPCR 0.0035 0.0089 0.0207
Brugia malayi Inositol polyphosphate kinase family protein 0.0007 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.003 0.0071 0.0105
Onchocerca volvulus 0.0035 0.0089 0.0931
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0019 0.0038 0.0089
Mycobacterium leprae Probable 6-phosphogluconolactonase DevB (6PGL) 0.0131 0.038 1
Loa Loa (eye worm) AGC/AKT protein kinase 0.0015 0.0028 0.004
Brugia malayi G protein-coupled receptor 0.0035 0.0089 0.0088
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0033 0.0325
Brugia malayi hypothetical protein 0.0035 0.0089 0.0088
Loa Loa (eye worm) hypothetical protein 0.0035 0.0089 0.0132
Loa Loa (eye worm) ryanodine receptor 0.0535 0.1611 0.2421
Echinococcus multilocularis high affinity choline transporter 1 0.0132 0.0383 0.089
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0035 0.0089 0.0088
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.001 0.0011 0.0015
Schistosoma mansoni beta-14-galactosyltransferase 34-related 0.0017 0.0033 0.0036
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0017 0.0033 0.0059
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0035 0.0089 0.0104
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0007 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0007 0.0003 0.0003
Echinococcus granulosus transient receptor potential cation channel 0.003 0.0071 0.0165
Echinococcus multilocularis short transient receptor potential channel 6 0.003 0.0071 0.0165
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0035 0.0089 0.0207
Schistosoma mansoni 60S ribosomal protein L21 0.003 0.0071 0.0082
Echinococcus granulosus tachykinin peptides receptor 99D 0.0035 0.0089 0.0207
Schistosoma mansoni glucosamine-6-phosphate isomerase 0.0038 0.0097 0.0114
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.003 0.0071 0.0082
Onchocerca volvulus 0.0148 0.0432 0.4645
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0029 0.0288
Trypanosoma cruzi fructose-bisphosphate aldolase, glycosomal, putative 0.0494 0.1486 0.2928
Brugia malayi hypothetical protein 0.0035 0.0089 0.0088
Echinococcus granulosus neuropeptide receptor A26 0.0035 0.0089 0.0207
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0021 0.0046 0.0085
Loa Loa (eye worm) calcium channel 0.003 0.0071 0.0105
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0038 0.0097 0.1022
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0003 0.0006
Echinococcus multilocularis voltage gated potassium channel 0.003 0.0071 0.0165
Toxoplasma gondii cyclin, N-terminal domain-containing protein 0.0011 0.0015 0.008
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.003 0.0071 0.0165
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.003 0.0071 0.0082
Entamoeba histolytica cell division protein kinase 2, putative 0.0019 0.0038 0.0397
Onchocerca volvulus 0.003 0.0071 0.0735
Loa Loa (eye worm) inositol polyphosphate kinase 0.0007 0.0003 0.0003
Echinococcus multilocularis neuropeptide Y receptor 0.0035 0.0089 0.0207
Echinococcus granulosus sodium channel protein 0.003 0.0071 0.0165
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.003 0.0071 0.0735
Schistosoma mansoni hypothetical protein 0.0035 0.0089 0.0104
Brugia malayi ion channel NompC 0.003 0.0071 0.007
Trypanosoma cruzi glucosamine-6-phosphate isomerase, putative 0.0038 0.0097 0.0189
Brugia malayi Thioredoxin reductase 0.0048 0.0126 0.0124
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0003 0.0006
Toxoplasma gondii N-acetylgalactosaminyl transferase 0.0017 0.0033 0.0198
Echinococcus multilocularis ryanodine receptor 44f 0.11 0.333 0.775
Brugia malayi Phosphatidylinositol-specific phospholipase C, X domain containing protein 0.01 0.0287 0.0286
Loa Loa (eye worm) galactosyltransferase 0.0157 0.0458 0.0687
Plasmodium falciparum inositol polyphosphate multikinase, putative 0.0007 0.0003 0.0011
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0038 0.0043
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.1983 0.6017 0.6016
Echinococcus multilocularis orexin receptor type 2 0.0035 0.0089 0.0207
Brugia malayi RE15519p 0.0035 0.0089 0.0088
Echinococcus granulosus transient receptor potential cation channel 0.003 0.0071 0.0165
Giardia lamblia Glucosamine-6-phosphate deaminase 0.0038 0.0097 1
Echinococcus multilocularis transient receptor potential cation channel 0.003 0.0071 0.0165
Trichomonas vaginalis inositol polyphosphate kinase, putative 0.0007 0.0003 0.0006
Schistosoma mansoni amine GPCR 0.0035 0.0089 0.0104
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.003 0.0071 0.0082
Schistosoma mansoni voltage-gated potassium channel 0.003 0.0071 0.0082
Echinococcus granulosus serine/threonine protein kinase 0.0012 0.0018 0.0042
Trypanosoma brucei cdc2-related kinase 1 0.0019 0.0038 0.007
Loa Loa (eye worm) hypothetical protein 0.0036 0.009 0.0133
Schistosoma mansoni voltage-dependent calcium channel 0.003 0.0071 0.0082
Loa Loa (eye worm) UDP-Galactose:b-N-acetylglucosamine b1,4-galactosyltransferase 4 0.0041 0.0106 0.0158
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0023 0.0052 0.0076
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.003 0.0071 0.0105
Toxoplasma gondii cyclin2 related protein 0.0011 0.0015 0.008
Loa Loa (eye worm) hypothetical protein 0.1418 0.4297 0.6461
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0035 0.0089 0.0088
Schistosoma mansoni beta-14-galactosyltransferase 0.0041 0.0106 0.0125
Loa Loa (eye worm) hypothetical protein 0.0035 0.0089 0.0132
Echinococcus multilocularis hyperpolarization activated cyclic 0.003 0.0071 0.0165
Echinococcus granulosus G protein coupled receptor 139 0.0035 0.0089 0.0207
Echinococcus multilocularis voltage dependent calcium channel 0.003 0.0071 0.0165
Echinococcus granulosus voltage gated potassium channel 0.003 0.0071 0.0165
Echinococcus granulosus tm gpcr rhodopsin 0.0035 0.0089 0.0207
Loa Loa (eye worm) hypothetical protein 0.0132 0.0383 0.0573
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0035 0.0089 0.0207
Toxoplasma gondii hypothetical protein 0.003 0.0071 0.0458
Leishmania major hypothetical protein, conserved 0.1137 0.3442 1
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.0132 0.0383 0.2558
Schistosoma mansoni amine GPCR 0.0035 0.0089 0.0104
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.003 0.0071 0.007
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0012 0.0018 0.0033
Trypanosoma cruzi phosphoinositide-specific phospholipase C, putative 0.0056 0.0151 0.0294
Brugia malayi Tachykinin-like peptides receptor 99D 0.0035 0.0089 0.0088
Loa Loa (eye worm) hypothetical protein 0.0035 0.0089 0.0132
Echinococcus multilocularis allatostatin A receptor 0.0035 0.0089 0.0207
Echinococcus granulosus hypothetical protein 0.003 0.0071 0.0165
Loa Loa (eye worm) voltage-gated potassium channel 0.003 0.0071 0.0105
Trypanosoma cruzi inositol polyphosphate kinase-like protein, putative 0.0007 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0035 0.0089 0.0132
Schistosoma mansoni voltage-gated potassium channel 0.003 0.0071 0.0082
Entamoeba histolytica phosphoglycerate mutase family protein, putative 0.0007 0.0003 0.0018
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0035 0.0089 0.0207
Brugia malayi beta-1,4-galactosyltransferase VII 0.0041 0.0106 0.0105
Echinococcus multilocularis rhodopsin orphan GPCR 0.0035 0.0089 0.0207
Brugia malayi p70 ribosomal S6 kinase beta 0.001 0.0011 0.001
Loa Loa (eye worm) hypothetical protein 0.2191 0.6651 1
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0016 0.0031 0.0201
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0007 0.0001 0.0003
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0031 0.0083
Schistosoma mansoni beta-14-galactosyltransferase 0.0157 0.0458 0.055
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0035 0.0089 0.0104
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0035 0.0089 0.0132
Loa Loa (eye worm) hypothetical protein 0.0035 0.0089 0.0132
Schistosoma mansoni beta-14-galactosyltransferase 0.0041 0.0106 0.0125
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.003 0.0071 0.0165
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.003 0.0071 0.0165
Loa Loa (eye worm) hypothetical protein 0.0035 0.0089 0.0132
Echinococcus granulosus neuropeptide FF receptor 2 0.0035 0.0089 0.0207
Trypanosoma brucei glycosylphosphatidylinositol-specific phospholipase C 0.0015 0.0027 0.0048
Trypanosoma cruzi inositol polyphosphate kinase, putative 0.0007 0.0003 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0013 0.0019 0.0182
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.001 0.0012 0.0018
Toxoplasma gondii transporter, cation channel family protein 0.003 0.0071 0.0458
Echinococcus multilocularis transient receptor potential cation channel 0.003 0.0071 0.0165
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0035 0.0089 0.0104
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0029 0.0288
Trypanosoma cruzi glucosamine-6-phosphate isomerase, putative 0.0038 0.0097 0.0189
Plasmodium falciparum fructose-bisphosphate aldolase 0.0494 0.1486 1
Echinococcus granulosus Metazoa galactosyltransferase 0.0157 0.0458 0.1065
Echinococcus granulosus potassium voltage gated channel subfamily H 0.003 0.0071 0.0165
Trypanosoma cruzi fructose-bisphosphate aldolase, glycosomal, putative 0.0494 0.1486 0.2928
Loa Loa (eye worm) hypothetical protein 0.0119 0.0344 0.0515
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0035 0.0089 0.0207
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0031 0.0056
Schistosoma mansoni voltage-gated cation channel 0.003 0.0071 0.0082
Toxoplasma gondii fructose-1,6-bisphosphate aldolase 0.0494 0.1486 1
Brugia malayi neuropeptide F receptor 0.0035 0.0089 0.0088
Onchocerca volvulus 0.0035 0.0089 0.0931
Schistosoma mansoni fructose 16-bisphosphate aldolase 0.0494 0.1486 0.1792
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0019 0.0038 0.0055
Schistosoma mansoni ryanodine receptor 1 skeletal muscle 0.0535 0.1611 0.1943
Brugia malayi cation channel family protein 0.003 0.0071 0.007
Echinococcus multilocularis g protein coupled receptor 0.0035 0.0089 0.0207
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0035 0.0089 0.0104
Loa Loa (eye worm) hypothetical protein 0.003 0.0071 0.0105
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0033 0.0325
Onchocerca volvulus 0.0035 0.0089 0.0931
Echinococcus multilocularis 6 phosphogluconolactonase 0.0131 0.038 0.0884
Echinococcus multilocularis neuropeptide FF receptor 2 0.0035 0.0089 0.0207
Toxoplasma gondii transporter, cation channel family protein 0.003 0.0071 0.0458
Trichomonas vaginalis PIKK family atypical protein kinase 0.0014 0.0023 0.0222
Schistosoma mansoni vesicular amine transporter 0.003 0.0071 0.0082
Echinococcus granulosus Ribosomal protein L34a 0.0115 0.0333 0.0774
Schistosoma mansoni two-pore calcium channel 0.003 0.0071 0.0082
Loa Loa (eye worm) Plcb4 protein 0.0083 0.0235 0.0352
Plasmodium vivax histone deacetylase 2, putative 0.0007 0.0003 0.0011
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0035 0.0089 0.0207
Giardia lamblia Glucose-6-phosphate 1-dehydrogenase 0.0038 0.0097 1
Trichomonas vaginalis AGC family protein kinase 0.0015 0.0028 0.0273
Echinococcus multilocularis neuropeptide Y receptor 0.0035 0.0089 0.0207
Echinococcus multilocularis sodium leak channel non selective protein 0.003 0.0071 0.0165
Loa Loa (eye worm) hypothetical protein 0.0035 0.0089 0.0132
Echinococcus multilocularis g-protein coupled receptor 0.0035 0.0089 0.0207
Schistosoma mansoni ryanodine receptor related 0.1983 0.6017 0.7266
Loa Loa (eye worm) hypothetical protein 0.2155 0.654 0.9833
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0029 0.0288
Onchocerca volvulus 0.0132 0.0383 0.4107
Trypanosoma brucei inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0125 0.0361 0.0706
Loa Loa (eye worm) glutathione reductase 0.0048 0.0126 0.0187
Leishmania major inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0119 0.0344 0.0992
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0035 0.0089 0.0088
Echinococcus granulosus short transient receptor potential channel 6 0.003 0.0071 0.0165
Echinococcus multilocularis potassium voltage gated channel protein 0.003 0.0071 0.0165
Loa Loa (eye worm) phosphatidylinositol 3 0.0021 0.0046 0.0067
Brugia malayi hypothetical protein 0.003 0.0071 0.007
Loa Loa (eye worm) ion channel NompC 0.003 0.0071 0.0105
Echinococcus granulosus voltage dependent calcium channel 0.003 0.0071 0.0165
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0016 0.0031 0.019
Echinococcus granulosus fmrfamide receptor 0.0035 0.0089 0.0207
Echinococcus multilocularis rhodopsin orphan GPCR 0.0035 0.0089 0.0207
Loa Loa (eye worm) hypothetical protein 0.0035 0.0089 0.0132
Echinococcus granulosus dro:myosuppressin receptor 0.0035 0.0089 0.0207
Echinococcus multilocularis neuropeptide receptor A26 0.0035 0.0089 0.0207
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0029 0.0288
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0031 0.0083
Echinococcus granulosus biogenic amine 5HT receptor 0.0035 0.0089 0.0207
Loa Loa (eye worm) hypothetical protein 0.003 0.0071 0.0105
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.003 0.0071 0.0165
Echinococcus multilocularis beta 1,4 galactosyltransferase 7 0.0041 0.0106 0.0248
Brugia malayi neuropeptide F receptor 0.0035 0.0089 0.0088
Brugia malayi cell division control protein 2 homolog 0.0019 0.0038 0.0037
Schistosoma mansoni voltage-gated potassium channel 0.003 0.0071 0.0082
Echinococcus multilocularis cytohesin 1 0.0132 0.0384 0.0893
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.003 0.0071 0.0082
Echinococcus granulosus 6 phosphogluconolactonase 0.0131 0.038 0.0884
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0038 0.0097 0.1022
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0016 0.0031 0.5
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0021 0.0046 0.0085
Trichomonas vaginalis PIKK family atypical protein kinase 0.0013 0.0019 0.0182
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0035 0.0089 0.0104
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0035 0.0089 0.0207
Echinococcus granulosus calcium activated potassium channel 0.003 0.0072 0.0169
Leishmania major hypothetical protein, conserved 0.0007 0.0003 0.0001
Schistosoma mansoni beta-14-galactosyltransferase 0.0041 0.0106 0.0125
Loa Loa (eye worm) fructose-bisphosphate aldolase 1 0.0494 0.1486 0.2233
Trichomonas vaginalis glutathione reductase, putative 0.0016 0.0031 0.0311
Echinococcus multilocularis rhodopsin orphan GPCR 0.0035 0.0089 0.0207
Schistosoma mansoni amine GPCR 0.0035 0.0089 0.0104
Echinococcus granulosus hyperpolarization activated cyclic 0.003 0.0071 0.0165
Loa Loa (eye worm) hypothetical protein 0.003 0.0071 0.0105
Loa Loa (eye worm) hypothetical protein 0.003 0.0071 0.0105
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0031 0.0056
Echinococcus granulosus neuropeptides capa receptor 0.0035 0.0089 0.0207
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0031 0.0059
Brugia malayi Dopamine receptor protein 2 0.0035 0.0089 0.0088
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0035 0.0089 0.0207
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.0132 0.0383 0.089
Schistosoma mansoni neuropeptide f receptor 76f 0.0035 0.0089 0.0104
Echinococcus granulosus beta 14 galactosyltransferase 7 0.0041 0.0106 0.0248
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0016 0.0031 0.0083
Entamoeba histolytica protein kinase, putative 0.001 0.0011 0.0104
Echinococcus granulosus orexin receptor type 2 0.0035 0.0089 0.0207
Loa Loa (eye worm) hypothetical protein 0.0007 0.0003 0.0003
Echinococcus granulosus two pore calcium channel protein 2 0.003 0.0071 0.0165
Plasmodium falciparum glutathione reductase 0.0016 0.0031 0.0201
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0.0031 0.003
Loa Loa (eye worm) hypothetical protein 0.0035 0.0089 0.0132
Schistosoma mansoni voltage-gated potassium channel 0.003 0.0071 0.0082
Echinococcus granulosus inositol polyphosphate kinase 0.0007 0.0003 0.0007
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0035 0.0089 0.0104
Loa Loa (eye worm) melatonin receptor type 1A 0.0035 0.0089 0.0132
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.003 0.0071 0.0082
Trypanosoma brucei glucosamine-6-phosphate isomerase, putative 0.0038 0.0097 0.0186
Brugia malayi CG13688-PA 0.0007 0.0003 0.0002
Toxoplasma gondii AGC kinase 0.001 0.0011 0.0053
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0007 0.0003 0.0003
Echinococcus multilocularis potassium voltage gated channel protein 0.003 0.0071 0.0165
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.003 0.0071 0.0082
Trichomonas vaginalis transcription factor, putative 0.0007 0.0003 0.0006
Loa Loa (eye worm) hypothetical protein 0.0035 0.0089 0.0132
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.003 0.0071 0.0165
Echinococcus granulosus stromal cell derived factor 2 0.0311 0.0927 0.2157
Onchocerca volvulus 0.0035 0.0089 0.0931
Echinococcus granulosus peptide allatostatin:somatostatin 0.0035 0.0089 0.0207
Brugia malayi Transient-receptor-potential like protein 0.003 0.0071 0.007
Onchocerca volvulus 0.005 0.0134 0.142
Echinococcus granulosus rhodopsin orphan GPCR 0.0035 0.0089 0.0207
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0031 0.0059
Schistosoma mansoni 6-phosphogluconolactonase 0.0131 0.038 0.0456
Loa Loa (eye worm) hypothetical protein 0.0017 0.0033 0.0047
Schistosoma mansoni serine/threonine protein kinase 0.0023 0.0052 0.0059
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0035 0.0089 0.0931
Schistosoma mansoni inositol 145-trisphosphate receptor 0.1873 0.5684 0.6863
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0016 0.0031 0.0201
Onchocerca volvulus 0.0035 0.0089 0.0931
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0016 0.0031 0.0056
Plasmodium falciparum protein kinase 5 0.0019 0.0038 0.0247
Brugia malayi Protein kinase domain containing protein 0.0015 0.0028 0.0026
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0035 0.0089 0.0104
Trichomonas vaginalis PIKK family atypical protein kinase 0.0007 0.0003 0.0003
Trypanosoma cruzi cdc2-related kinase 3 0.0019 0.0038 0.0072
Echinococcus multilocularis sodium:glucose cotransporter 2 0.0517 0.1554 0.3616
Loa Loa (eye worm) hypothetical protein 0.0035 0.0089 0.0132
Trichomonas vaginalis PIKK family atypical protein kinase 0.0007 0.0003 0.0003
Schistosoma mansoni voltage-gated potassium channel 0.003 0.0071 0.0082
Echinococcus multilocularis neuropeptides capa receptor 0.0035 0.0089 0.0207
Echinococcus granulosus potassium voltage gated channel subfamily D 0.003 0.0071 0.0165
Echinococcus granulosus voltage gated potassium channel 0.003 0.0071 0.0165
Echinococcus multilocularis two pore calcium channel protein 1 0.003 0.0071 0.0165
Schistosoma mansoni phenylalanine decarboxylase 0.0041 0.0106 0.0125
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0015 0.0134
Plasmodium falciparum histone deacetylase 2 0.0007 0.0003 0.0011
Leishmania major calcium channel protein, putative,ion transporter, putative 0.003 0.0071 0.0198
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0033 0.0325
Trichomonas vaginalis PIKK family atypical protein kinase 0.0013 0.002 0.0186
Echinococcus multilocularis transfer RNA-Gly 0.003 0.0071 0.0165
Schistosoma mansoni neuropeptide F-like receptor 0.0035 0.0089 0.0104
Echinococcus multilocularis sodium channel protein 0.003 0.0071 0.0165
Onchocerca volvulus 0.0311 0.0927 1
Loa Loa (eye worm) hypothetical protein 0.0035 0.0089 0.0132
Echinococcus granulosus beta 14 N acetylgalactosaminyltransferase 0.0041 0.0106 0.0248
Loa Loa (eye worm) hypothetical protein 0.003 0.0071 0.0105
Echinococcus granulosus polypeptide N acetylgalactosaminyltransferase 0.0017 0.0033 0.0076
Onchocerca volvulus 0.0035 0.0089 0.0931
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.003 0.0071 0.0082
Echinococcus granulosus fructose 16 bisphosphate aldolase 0.0494 0.1486 0.3458
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0035 0.0089 0.0207
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.003 0.0071 0.0165
Loa Loa (eye worm) hypothetical protein 0.0035 0.0089 0.0132
Leishmania major hypothetical protein, conserved 0.0015 0.0027 0.007
Trypanosoma cruzi fructose-bisphosphate aldolase, glycosomal, putative 0.0494 0.1486 0.2928
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0035 0.0089 0.0104
Echinococcus granulosus sex peptide receptor 0.0035 0.0089 0.0207
Echinococcus multilocularis stromal cell derived factor 2 0.0311 0.0927 0.2157
Loa Loa (eye worm) hypothetical protein 0.005 0.0134 0.02
Giardia lamblia GTOR 0.0021 0.0046 0.4646
Loa Loa (eye worm) hypothetical protein 0.0035 0.0089 0.0132
Brugia malayi Dopamine receptor protein 1 0.0035 0.0089 0.0088
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0046 0.0468
Entamoeba histolytica glucosamine-6-phosphate isomerase, putative 0.0038 0.0097 0.1033
Echinococcus multilocularis neuropeptide receptor 0.0035 0.0089 0.0207
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.003 0.0071 0.0165
Echinococcus multilocularis beta 1,4 N acetylgalactosaminyltransferase 0.0041 0.0106 0.0248
Loa Loa (eye worm) ryanodine receptor 0.003 0.0071 0.0105
Trypanosoma brucei cyclin 2 0.0011 0.0015 0.0024
Schistosoma mansoni transient receptor potential channel 0.003 0.0071 0.0082
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0016 0.0031 0.0073
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.003 0.0071 0.0134
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.003 0.0071 0.007
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.003 0.0071 0.0165
Echinococcus multilocularis cyclin dependent kinase 5 0.0019 0.0038 0.0089
Trichomonas vaginalis AGC family protein kinase 0.0015 0.0028 0.0273
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0046 0.0468
Echinococcus granulosus transient receptor potential cation channel 0.003 0.0071 0.0165
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.003 0.0071 0.0137
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0016 0.0146
Loa Loa (eye worm) phosphatidylinositol-specific phospholipase C 0.0015 0.0027 0.0039
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.1672 0.5071 1
Brugia malayi hypothetical protein 0.0035 0.0089 0.0088
Treponema pallidum glucose-6-phosphate 1-dehydrogenase 0.0131 0.038 1
Trichomonas vaginalis kcs1 protein, putative 0.0007 0.0003 0.0006
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0035 0.0089 0.0104
Schistosoma mansoni phospholipase C-like protein 2 plc-L2 0.0063 0.0172 0.0205
Echinococcus multilocularis inositol polyphosphate multikinase 0.0007 0.0003 0.0007
Schistosoma mansoni voltage-gated potassium channel 0.003 0.0071 0.0082
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0016 0.0145
Schistosoma mansoni phospholipase C-like protein 2 plc-L2 0.0073 0.0204 0.0243
Brugia malayi sulfakinin receptor protein 0.0035 0.0089 0.0088
Loa Loa (eye worm) G-protein coupled receptor 0.0035 0.0089 0.0132
Echinococcus multilocularis rac serine:threonine kinase 0.0012 0.0018 0.0042
Schistosoma mansoni guanyl-nucleotide exchange factor 0.0132 0.0384 0.046
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0035 0.0089 0.0132
Echinococcus granulosus potassium voltage gated channel protein 0.003 0.0071 0.0165
Brugia malayi fructose-bisphosphate aldolase 1 0.0494 0.1486 0.1485
Echinococcus granulosus short transient receptor potential channel 6 0.003 0.0071 0.0165
Onchocerca volvulus 0.0015 0.0027 0.0259
Echinococcus granulosus tm gpcr rhodopsin 0.0035 0.0089 0.0207
Loa Loa (eye worm) neuropeptide F receptor 0.0035 0.0089 0.0132
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0012 0.0018 0.0017
Plasmodium falciparum phosphoinositide-specific phospholipase C 0.0036 0.009 0.0597
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0019 0.0038 0.0055
Echinococcus multilocularis sex peptide receptor 0.0035 0.0089 0.0207
Schistosoma mansoni voltage-gated potassium channel 0.003 0.0071 0.0082
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0035 0.0089 0.0104
Schistosoma mansoni biogenic amine (5HT) receptor 0.0035 0.0089 0.0104
Brugia malayi hypothetical protein 0.0035 0.0089 0.0088
Trichomonas vaginalis AGC family protein kinase 0.0023 0.0052 0.0535
Onchocerca volvulus 0.0035 0.0089 0.0931
Echinococcus multilocularis fmrfamide receptor 0.0035 0.0089 0.0207
Echinococcus granulosus inositol polyphosphate multikinase 0.0007 0.0003 0.0007
Echinococcus multilocularis 1 phosphatidylinositol 4,5 bisphosphate 0.0086 0.0242 0.0563
Schistosoma mansoni beta-14-galactosyltransferase 34-related 0.0041 0.0106 0.0125
Echinococcus multilocularis solute carrier family 5 0.0517 0.1554 0.3616
Giardia lamblia NADH oxidase lateral transfer candidate 0.0016 0.0031 0.3131
Trypanosoma cruzi CYC2-like cyclin, putative 0.0011 0.0015 0.0027
Plasmodium falciparum glutathione reductase 0.0048 0.0126 0.0838
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.003 0.0071 0.074
Brugia malayi Serotonin receptor 0.0035 0.0089 0.0088
Leishmania major phospholipase c-like protein 0.0056 0.0151 0.0429
Brugia malayi AKH receptor 0.0035 0.0089 0.0088
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0016 0.0031 0.0056
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0035 0.0089 0.0104
Schistosoma mansoni neuropeptide receptor 0.0035 0.0089 0.0104
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.003 0.0071 0.007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0007 0.0003 0.0003
Brugia malayi G-protein coupled receptor 0.0035 0.0089 0.0088
Echinococcus granulosus fructose 16 bisphosphate aldolase 0.0494 0.1486 0.3458
Entamoeba histolytica PH domain containing protein kinase, putative 0.0012 0.0018 0.0181
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0035 0.0089 0.0104
Echinococcus granulosus cyclic nucleotide gated cation channel 0.003 0.0071 0.0165
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0016 0.0146
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0016 0.0145
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.003 0.0071 0.0165
Brugia malayi putative neuropeptide receptor NPR1 0.0035 0.0089 0.0088
Brugia malayi Galactosyltransferase family protein 0.0157 0.0458 0.0457
Trichomonas vaginalis PIKK family atypical protein kinase 0.0014 0.0025 0.0237
Loa Loa (eye worm) phosphatidylinositol 3 0.0007 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.003 0.0071 0.0105
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.003 0.0071 0.0082
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0003 0.0006
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0021 0.0046 0.0479
Loa Loa (eye worm) hypothetical protein 0.003 0.0071 0.0105
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0035 0.0089 0.0207
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0021 0.0046 0.0052
Echinococcus granulosus transient receptor potential gamma protein 0.003 0.0071 0.0165
Brugia malayi Galactosyltransferase family protein 0.0041 0.0106 0.0105
Echinococcus granulosus transient receptor potential cation channel 0.003 0.0071 0.0165
Echinococcus multilocularis short transient receptor potential channel 6 0.003 0.0071 0.0165
Schistosoma mansoni biogenic amine receptor 0.0035 0.0089 0.0104
Echinococcus multilocularis ryanodine receptor 44f 0.1418 0.4297 1
Loa Loa (eye worm) hypothetical protein 0.0119 0.0344 0.0515
Loa Loa (eye worm) hypothetical protein 0.0035 0.0089 0.0132
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0035 0.0089 0.0207
Plasmodium vivax glutathione reductase, putative 0.0048 0.0126 0.0838
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.003 0.0071 0.0082
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0029 0.0288
Schistosoma mansoni transient receptor potential channel 4 0.003 0.0071 0.0082
Loa Loa (eye worm) hypothetical protein 0.0035 0.0089 0.0132
Leishmania major phosphoinositide-specific phospholipase C, putative 0.0053 0.0144 0.041
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.003 0.0071 0.0165
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0021 0.0046 0.0044
Loa Loa (eye worm) galactosyltransferase 0.0041 0.0106 0.0158
Loa Loa (eye worm) hypothetical protein 0.0035 0.0089 0.0132
Schistosoma mansoni voltage-gated potassium channel 0.003 0.0071 0.0082
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0019 0.0038 0.0236
Echinococcus granulosus rhodopsin orphan GPCR 0.0035 0.0089 0.0207
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0035 0.0089 0.0207
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.003 0.0071 0.074
Echinococcus granulosus neuropeptide s receptor 0.0035 0.0089 0.0207
Loa Loa (eye worm) hypothetical protein 0.003 0.0071 0.0105
Echinococcus multilocularis transient receptor potential gamma protein 0.003 0.0071 0.0165
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0031 0.0059
Plasmodium falciparum cyclin, putative 0.0011 0.0015 0.0091
Brugia malayi Inositol polyphosphate kinase family protein 0.0007 0.0003 0.0002
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0021 0.0046 0.0087
Echinococcus multilocularis thioredoxin glutathione reductase 0.0048 0.0126 0.0293
Trypanosoma cruzi cdc2-related kinase 3 0.0019 0.0038 0.0072
Schistosoma mansoni neuropeptide receptor 0.0035 0.0089 0.0104
Echinococcus granulosus shaker cognate 0.003 0.0071 0.0165
Brugia malayi phosphoinositide-dependent protein kinase I 0.0023 0.0052 0.0051
Loa Loa (eye worm) hypothetical protein 0.0035 0.0089 0.0132
Echinococcus multilocularis fructose bisphosphate aldolase class I 0.0494 0.1486 0.3458
Loa Loa (eye worm) hypothetical protein 0.003 0.0071 0.0105
Onchocerca volvulus 0.0035 0.0089 0.0931
Onchocerca volvulus 0.0035 0.0089 0.0931
Schistosoma mansoni serine/threonine-protein kinase 0.0012 0.0018 0.0019
Echinococcus multilocularis Metazoa galactosyltransferase 0.0132 0.0384 0.0893
Trypanosoma brucei CYC2-like cyclin, putative 0.0011 0.0015 0.0024
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0035 0.0089 0.0132
Schistosoma mansoni n-acetylgalactosaminyltransferase 0.0017 0.0033 0.0036
Loa Loa (eye worm) hypothetical protein 0.003 0.0071 0.0105
Entamoeba histolytica inositol hexakisphosphate kinase, putative 0.0007 0.0003 0.0018
Echinococcus granulosus cyclin dependent kinase 5 0.0019 0.0038 0.0089
Echinococcus multilocularis conserved hypothetical protein 0.003 0.0071 0.0165
Brugia malayi Variant SH3 domain containing protein 0.0043 0.0113 0.0112
Echinococcus multilocularis inositol polyphosphate kinase 0.0007 0.0003 0.0007
Schistosoma mansoni biogenic amine (5HT) receptor 0.0035 0.0089 0.0104
Trypanosoma brucei fructose-bisphosphate aldolase, glycosomal, putative 0.0494 0.1486 0.2926
Echinococcus granulosus neuropeptide Y receptor 0.0035 0.0089 0.0207
Schistosoma mansoni serine/threonine-protein kinase 0.0012 0.0018 0.0019
Schistosoma mansoni sodium/solute symporter 0.0132 0.0383 0.0459
Loa Loa (eye worm) hypothetical protein 0.0035 0.0089 0.0132
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.003 0.0071 0.0105
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0029 0.0288
Giardia lamblia Kinase, CMGC CDK 0.0019 0.0038 0.3849
Schistosoma mansoni voltage-gated potassium channel 0.003 0.0071 0.0082
Echinococcus multilocularis voltage gated potassium channel 0.003 0.0071 0.0165
Loa Loa (eye worm) glycosyl transferase 0.0017 0.0033 0.0047
Entamoeba histolytica inositol hexakisphosphate kinase, putative 0.0007 0.0003 0.0018
Leishmania major CYC2-like cyclin, putative 0.0011 0.0015 0.0035
Echinococcus granulosus neuropeptide receptor 0.0035 0.0089 0.0207
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0031 0.0059
Trichomonas vaginalis kcs1 protein, putative 0.0007 0.0003 0.0006
Echinococcus multilocularis sodium:myo inositol cotransporter 0.0517 0.1554 0.3616
Leishmania major phosphatidylinositol-specific phospholipase-like protein 0.0036 0.009 0.0254
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.003 0.0071 0.0082
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0021 0.0046 0.0479
Echinococcus granulosus 7tm_1 domain containing protein 0.0035 0.0089 0.0207
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0035 0.0089 0.0104
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0019 0.0038 0.0055
Trichomonas vaginalis PIKK family atypical protein kinase 0.0013 0.002 0.0186
Trichomonas vaginalis CMGC family protein kinase 0.0019 0.0038 0.0385
Schistosoma mansoni voltage-gated potassium channel 0.003 0.0071 0.0082
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.003 0.0071 0.007
Loa Loa (eye worm) MIR domain-containing protein 0.0311 0.0927 0.1392
Echinococcus multilocularis potassium large conductance calcium activated 0.003 0.0071 0.0165
Schistosoma mansoni adenoreceptor 0.0035 0.0089 0.0104
Schistosoma mansoni hypothetical protein 0.0035 0.0089 0.0104
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0046 0.0468
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0035 0.0089 0.0207
Trichomonas vaginalis AGC family protein kinase 0.0015 0.0028 0.0273
Trichomonas vaginalis mercuric reductase, putative 0.0016 0.0031 0.0311
Trypanosoma cruzi inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0119 0.0344 0.0676
Leishmania major fructose-1,6-bisphosphate aldolase 0.0494 0.1486 0.4313
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0035 0.0089 0.0104
Brugia malayi putative neuropeptide receptor 0.0035 0.0089 0.0088
Echinococcus multilocularis neuropeptide s receptor 0.0035 0.0089 0.0207
Echinococcus granulosus neuropeptide Y receptor 0.0035 0.0089 0.0207
Schistosoma mansoni beta-14-galactosyltransferase 0.0157 0.0458 0.055
Loa Loa (eye worm) hypothetical protein 0.0035 0.0089 0.0132
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.003 0.0071 0.0082
Echinococcus granulosus sodium leak channel non selective protein 0.003 0.0071 0.0165
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0017 0.0033 0.0087
Echinococcus granulosus potassium voltage gated channel protein 0.003 0.0071 0.0165
Schistosoma mansoni fructose 16-bisphosphate aldolase 0.0494 0.1486 0.1792
Entamoeba histolytica protein kinase, putative 0.0015 0.0028 0.0285
Echinococcus granulosus thioredoxin glutathione reductase 0.0048 0.0126 0.0293
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.003 0.0071 0.0082
Echinococcus multilocularis two pore calcium channel protein 2 0.003 0.0071 0.0165
Echinococcus granulosus rhodopsin orphan GPCR 0.0035 0.0089 0.0207
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.003 0.0071 0.0165
Schistosoma mansoni inositol 145-trisphosphate receptor 0.2727 0.828 1
Onchocerca volvulus 0.0035 0.0089 0.0931
Loa Loa (eye worm) hypothetical protein 0.0035 0.0089 0.0132
Onchocerca volvulus 0.0035 0.0089 0.0931
Echinococcus granulosus sodium:glucose cotransporter 2 0.0517 0.1554 0.3616
Brugia malayi Cyclic-nucleotide gated cation channel 0.003 0.0071 0.007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0029 0.0288
Brugia malayi Protein kinase domain containing protein 0.0033 0.0081 0.008
Schistosoma mansoni transient receptor potential channel 0.003 0.0071 0.0082
Mycobacterium tuberculosis Conserved hypothetical protein 0.0101 0.0287 1
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0007 0.0003 0.0007
Toxoplasma gondii transporter, cation channel family protein 0.003 0.0071 0.0458
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.003 0.0071 0.007
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.003 0.0071 0.007
Schistosoma mansoni beta-14-galactosyltransferase 0.0024 0.0055 0.0063
Trypanosoma brucei trypanothione reductase 0.0048 0.0126 0.0243
Schistosoma mansoni phospholipase C beta 0.0083 0.0235 0.0281
Echinococcus granulosus cyclin dependent kinase 1 0.0019 0.0038 0.0089
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.0132 0.0383 0.089
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.003 0.0071 0.0165
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.003 0.0071 0.0165
Echinococcus multilocularis G protein coupled receptor 139 0.0035 0.0089 0.0207
Echinococcus granulosus neuropeptides capa receptor 0.0035 0.0089 0.0207
Echinococcus multilocularis potassium voltage gated channel protein 0.003 0.0071 0.0165
Loa Loa (eye worm) hypothetical protein 0.0035 0.0089 0.0132
Leishmania major inositol polyphosphate kinase-like protein, putative 0.0007 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.003 0.0071 0.0105
Echinococcus granulosus ryanodine receptor 44f 0.11 0.333 0.775
Loa Loa (eye worm) hypothetical protein 0.0035 0.0089 0.0132
Echinococcus multilocularis hyperpolarization activated cyclic 0.003 0.0071 0.0165
Echinococcus granulosus sodium:myo inositol cotransporter 0.0517 0.1554 0.3616
Loa Loa (eye worm) voltage-gated potassium channel 0.003 0.0071 0.0105
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.003 0.0071 0.0082
Echinococcus multilocularis fmrfamide receptor 0.0035 0.0089 0.0207
Loa Loa (eye worm) hypothetical protein 0.003 0.0071 0.0105
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0033 0.0325
Leishmania major trypanothione reductase 0.0048 0.0126 0.0358
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.003 0.0071 0.007
Echinococcus granulosus cytohesin 1 0.0132 0.0384 0.0893
Schistosoma mansoni neuropeptide receptor 0.0035 0.0089 0.0104
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0021 0.0046 0.0107
Onchocerca volvulus Neuropeptide F receptor homolog 0.0035 0.0089 0.0931
Echinococcus granulosus g protein coupled receptor 0.0035 0.0089 0.0207
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.003 0.0071 0.0165
Plasmodium vivax phospholipase C-like, putative 0.0036 0.009 0.0597
Echinococcus granulosus potassium voltage gated channel subfamily D 0.003 0.0071 0.0165
Plasmodium vivax thioredoxin reductase, putative 0.0048 0.0126 0.0838
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0035 0.0089 0.0207
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0007 0.0001 0.0003
Schistosoma mansoni neuropeptide F-like receptor 0.0035 0.0089 0.0104
Loa Loa (eye worm) hypothetical protein 0.0035 0.0089 0.0132
Trichomonas vaginalis 6-phosphogluconolactonase, putative 0.0038 0.0097 0.1022
Trypanosoma brucei rac serine-threonine kinase, putative 0.0015 0.0028 0.0049
Entamoeba histolytica PH domain containing protein kinase, putative 0.0012 0.0018 0.0181
Loa Loa (eye worm) inositol polyphosphate kinase 0.0007 0.0003 0.0003
Leishmania major 6-phosphogluconolactonase 0.0131 0.038 0.1097
Trypanosoma cruzi Protein kinase B 0.0012 0.0018 0.0033
Entamoeba histolytica protein kinase, putative 0.0023 0.0052 0.0547
Chlamydia trachomatis 6-phosphogluconolactonase 0.0131 0.038 1
Onchocerca volvulus 0.0035 0.0089 0.0931
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.0241 0.0715 0.086
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0035 0.0089 0.0104
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0021 0.0046 0.0107
Brugia malayi Phosphatidylinositol-specific phospholipase C, X domain containing protein 0.0015 0.0027 0.0026
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.003 0.0071 0.0458
Trichomonas vaginalis inositol polyphosphate multikinase, putative 0.0007 0.0003 0.0006
Trichomonas vaginalis CMGC family protein kinase 0.0019 0.0038 0.0385
Loa Loa (eye worm) hypothetical protein 0.0035 0.0089 0.0132
Schistosoma mansoni inositol transporter 0.0517 0.1554 0.1874
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0031 0.0059
Loa Loa (eye worm) hypothetical protein 0.003 0.0071 0.0105
Loa Loa (eye worm) fructose-bisphosphate aldolase 2 0.0494 0.1486 0.2233
Brugia malayi glutathione reductase 0.0048 0.0126 0.0124
Schistosoma mansoni hypothetical protein 0.0035 0.0089 0.0104
Entamoeba histolytica MIR domain protein 0.0311 0.0927 1
Plasmodium falciparum glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase 0.0038 0.0097 0.0644
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.003 0.0071 0.007
Echinococcus granulosus ryanodine receptor 44f 0.1418 0.4297 1
Brugia malayi Melatonin receptor type 1A 0.0035 0.0089 0.0088
Loa Loa (eye worm) hypothetical protein 0.0136 0.0395 0.0592
Onchocerca volvulus 0.0035 0.0089 0.0931
Trypanosoma brucei inositol polyphosphate multikinase 0.0007 0.0003 0.0001
Echinococcus granulosus potassium voltage gated channel protein 0.003 0.0071 0.0165
Loa Loa (eye worm) hypothetical protein 0.003 0.0071 0.0105
Echinococcus granulosus rhodopsin orphan GPCR 0.0035 0.0089 0.0207
Echinococcus granulosus biogenic amine 5HT receptor 0.0035 0.0089 0.0207
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.003 0.0071 0.0165
Entamoeba histolytica cell division protein kinase 2, putative 0.0019 0.0038 0.0397
Brugia malayi voltage-dependent calcium channel 0.003 0.0071 0.007
Loa Loa (eye worm) hypothetical protein 0.0035 0.0089 0.0132
Trypanosoma cruzi CYC2-like cyclin 6, putative 0.0011 0.0015 0.0027
Schistosoma mansoni growth hormone secretagogue receptor 0.0035 0.0089 0.0104
Schistosoma mansoni high-affinity choline transporter 0.0132 0.0383 0.0459
Schistosoma mansoni voltage-gated potassium channel 0.003 0.0071 0.0082
Echinococcus multilocularis serotonin receptor 0.0035 0.0089 0.0207
Echinococcus multilocularis cyclin dependent kinase 1 0.0019 0.0038 0.0089
Schistosoma mansoni beta-14-galactosyltransferase 0.0041 0.0106 0.0125
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0035 0.0089 0.0104
Loa Loa (eye worm) hypothetical protein 0.0035 0.0089 0.0132
Echinococcus granulosus solute carrier family 5 0.0517 0.1554 0.3616
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0036 0.0365
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0016 0.0031 0.0034
Loa Loa (eye worm) thioredoxin reductase 0.0048 0.0126 0.0187
Toxoplasma gondii glucose-6-phosphate 1-dehydrogenase 0.0038 0.0097 0.0633
Schistosoma mansoni phospholipase C beta 0.0015 0.0027 0.0029
Toxoplasma gondii hypothetical protein 0.003 0.0071 0.0458
Plasmodium vivax cyclin, putative 0.0011 0.0015 0.0091
Loa Loa (eye worm) voltage-gated calcium channel 0.003 0.0071 0.0105
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.003 0.0071 0.007
Echinococcus granulosus potassium voltage gated channel subfamily A 0.003 0.0071 0.0165
Toxoplasma gondii glycosyl transferase 0.0017 0.0033 0.0198
Loa Loa (eye worm) cytohesin 3 0.0132 0.0384 0.0575
Echinococcus multilocularis transient receptor potential cation channel 0.003 0.0071 0.0165
Schistosoma mansoni opsin-like receptor 0.0035 0.0089 0.0104
Schistosoma mansoni hypothetical protein 0.0035 0.0089 0.0104
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0016 0.0145
Schistosoma mansoni voltage-gated potassium channel 0.003 0.0071 0.0082
Brugia malayi hypothetical protein 0.0035 0.0089 0.0088
Onchocerca volvulus 0.0035 0.0089 0.0931
Trichomonas vaginalis AGC family protein kinase 0.0023 0.0052 0.0535
Schistosoma mansoni voltage-gated potassium channel 0.003 0.0071 0.0082
Echinococcus multilocularis transient receptor potential cation channel 0.003 0.0071 0.0165
Echinococcus granulosus fructose 16 bisphosphate aldolase 0.0494 0.1486 0.3458
Echinococcus granulosus cyclin dependent kinase 0.0019 0.0038 0.0089
Echinococcus multilocularis Ribosomal protein L34a 0.0115 0.0333 0.0774
Echinococcus multilocularis transient receptor potential cation channel 0.003 0.0071 0.0165
Brugia malayi G-protein coupled receptor 0.0035 0.0089 0.0088
Loa Loa (eye worm) hypothetical protein 0.0032 0.008 0.0118
Schistosoma mansoni inositol transporter 0.0517 0.1554 0.1874
Loa Loa (eye worm) voltage-dependent calcium channel 0.003 0.0071 0.0105
Loa Loa (eye worm) hypothetical protein 0.0035 0.0089 0.0132
Loa Loa (eye worm) hypothetical protein 0.0035 0.0089 0.0132
Schistosoma mansoni hypothetical protein 0.003 0.0071 0.0082
Trypanosoma brucei cdc2-related kinase 3 0.0019 0.0038 0.007
Echinococcus granulosus g-protein coupled receptor 0.0035 0.0089 0.0207
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.003 0.0071 0.0105
Onchocerca volvulus 0.0035 0.0089 0.0931
Schistosoma mansoni beta-14-galactosyltransferase 0.0041 0.0106 0.0125
Toxoplasma gondii thioredoxin reductase 0.0048 0.0126 0.0827
Loa Loa (eye worm) hypothetical protein 0.0035 0.0089 0.0132
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0023 0.0052 0.0121
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0016 0.0146
Brugia malayi hypothetical protein 0.0035 0.0089 0.0088
Trichomonas vaginalis AGC family protein kinase 0.0009 0.0009 0.007
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.003 0.0071 0.0165
Loa Loa (eye worm) hypothetical protein 0.003 0.0071 0.0105
Schistosoma mansoni voltage-gated potassium channel 0.003 0.0071 0.0082
Plasmodium falciparum thioredoxin reductase 0.0016 0.0031 0.0201
Echinococcus granulosus potassium voltage gated channel protein 0.003 0.0071 0.0165
Entamoeba histolytica inositol hexaphosphate kinase, putative 0.0007 0.0003 0.0018
Echinococcus granulosus g protein coupled receptor 0.0035 0.0089 0.0207
Loa Loa (eye worm) hypothetical protein 0.003 0.0071 0.0105
Echinococcus multilocularis cyclin dependent kinase 1 0.0019 0.0038 0.0089
Echinococcus granulosus two pore calcium channel protein 1 0.003 0.0071 0.0165
Plasmodium falciparum inositol polyphosphate kinase, putative 0.0007 0.0003 0.0011
Echinococcus multilocularis neuropeptide receptor 0.0035 0.0089 0.0207
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.003 0.0071 0.0082
Loa Loa (eye worm) hypothetical protein 0.0035 0.0089 0.0132

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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