Detailed information for compound 2069264

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 329.321 | Formula: C14H18F3N5O
  • H donors: 0 H acceptors: 2 LogP: 0.56 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: FC(Cn1ccnc1CN1CCOC(C1)Cn1cccn1)(F)F
  • InChi: 1S/C14H18F3N5O/c15-14(16,17)11-21-5-3-18-13(21)10-20-6-7-23-12(8-20)9-22-4-1-2-19-22/h1-5,12H,6-11H2
  • InChiKey: JLGTWPOSLLOAPU-UHFFFAOYSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Schistosoma mansoni loxhd1 0.001 0.0018 0.0017
Mycobacterium tuberculosis Probable oxidoreductase 0.0036 0.0128 0.1927
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0019 0.0057 0.0054
Echinococcus granulosus transient receptor potential cation channel 0.0019 0.0057 0.0135
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0153 0.0629 0.7377
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0019 0.0057 0.0135
Loa Loa (eye worm) hypothetical protein 0.0082 0.0325 0.0467
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0013 0.0031 0.0345
Schistosoma mansoni voltage-gated cation channel 0.0019 0.0057 0.0064
Trichomonas vaginalis PIKK family atypical protein kinase 0.0008 0.0008 0.0069
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0016 0.0041 0.0095
Loa Loa (eye worm) hypothetical protein 0.0013 0.0031 0.004
Echinococcus granulosus dna polymerase kappa 0.0047 0.0174 0.0428
Entamoeba histolytica thioredoxin reductase, putative 0.0013 0.0031 0.0324
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0019 0.0057 0.0135
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0047 0.0174 0.0428
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0302 0.0355
Loa Loa (eye worm) voltage-gated potassium channel 0.0019 0.0057 0.0078
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0019 0.0057 0.0135
Echinococcus multilocularis thioredoxin glutathione reductase 0.0131 0.0537 0.1341
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0019 0.0057 0.0961
Loa Loa (eye worm) AGC/AKT protein kinase 0.0015 0.0038 0.005
Entamoeba histolytica cell division protein kinase 2, putative 0.0013 0.003 0.0305
Trypanosoma brucei DNA polymerase IV, putative 0.0047 0.0174 0.037
Echinococcus multilocularis potassium voltage gated channel protein 0.0019 0.0057 0.0135
Echinococcus granulosus lamin dm0 0.0033 0.0114 0.0276
Echinococcus multilocularis voltage dependent calcium channel 0.0019 0.0057 0.0135
Loa Loa (eye worm) hypothetical protein 0.0082 0.0325 0.0467
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0057 0.0064
Loa Loa (eye worm) doublecortin family protein 0.001 0.0018 0.0021
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0153 0.0629 0.7372
Toxoplasma gondii hypothetical protein 0.0019 0.0057 0.0961
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0013 0.0031 0.0069
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0019 0.0057 0.0078
Loa Loa (eye worm) hypothetical protein 0.0025 0.0079 0.011
Echinococcus granulosus sodium channel protein 0.0019 0.0057 0.0135
Schistosoma mansoni rab6-interacting 0.001 0.0018 0.0017
Loa Loa (eye worm) hypothetical protein 0.0019 0.0057 0.0078
Echinococcus granulosus stromal cell derived factor 2 0.0205 0.0853 0.2133
Trichomonas vaginalis PIKK family atypical protein kinase 0.0009 0.0011 0.0112
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0047 0.0174 0.0247
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0036 0.0128 0.0148
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0037 0.0408
Schistosoma mansoni hypothetical protein 0.0019 0.0057 0.0064
Echinococcus multilocularis protein kinase c iota type 0.001 0.0017 0.0034
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0007 0.0004 0.0008
Brugia malayi hypothetical protein 0.0019 0.0057 0.0054
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0019 0.0057 0.0064
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0019 0.0057 0.0135
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0019 0.0057 0.0054
Loa Loa (eye worm) hypothetical protein 0.0047 0.0174 0.0247
Brugia malayi protein kinase C II. 0.0012 0.0026 0.0023
Echinococcus multilocularis conserved hypothetical protein 0.0019 0.0057 0.0135
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0013 0.0031 0.004
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0013 0.0031 0.0052
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0013 0.0031 0.0463
Echinococcus multilocularis transient receptor potential gamma protein 0.0019 0.0057 0.0135
Schistosoma mansoni ryanodine receptor related 0.1308 0.5582 0.6642
Schistosoma mansoni serine/threonine protein kinase 0.0013 0.003 0.0031
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0019 0.0057 0.0135
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0019 0.0057 0.0135
Loa Loa (eye worm) hypothetical protein 0.0019 0.0057 0.0078
Echinococcus multilocularis 1 phosphatidylinositol 4,5 bisphosphate 0.0059 0.0229 0.0566
Trichomonas vaginalis PIKK family atypical protein kinase 0.0009 0.0011 0.0108
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0019 0.0057 0.0135
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0036 0.0128 0.0124
Trypanosoma brucei hypothetical protein, conserved 0.0014 0.0036 0.0077
Echinococcus multilocularis RUN 0.001 0.0018 0.0037
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0036 0.0128 0.23
Schistosoma mansoni transient receptor potential channel 0.0019 0.0057 0.0064
Loa Loa (eye worm) hypothetical protein 0.0015 0.0039 0.0051
Toxoplasma gondii target of rapamycin (TOR), putative 0.0011 0.0021 0.0261
Trypanosoma cruzi cdc2-related kinase 3 0.0013 0.003 0.0049
Loa Loa (eye worm) ryanodine receptor 0.0353 0.1488 0.2156
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0019 0.0057 0.0078
Loa Loa (eye worm) hypothetical protein 0.001 0.0018 0.0021
Loa Loa (eye worm) hypothetical protein 0.0007 0.0004 0.0000044595
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0019 0.0057 0.0064
Echinococcus multilocularis potassium voltage gated channel protein 0.0019 0.0057 0.0135
Schistosoma mansoni guanyl-nucleotide exchange factor 0.0091 0.0364 0.0429
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0021 0.022
Loa Loa (eye worm) hypothetical protein 0.0019 0.0057 0.0078
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0013 0.003 0.0433
Treponema pallidum fructose-bisphosphate aldolase 0.0153 0.0629 1
Schistosoma mansoni sulfide quinone reductase 0.0013 0.0031 0.0033
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0013 0.0031 0.0052
Schistosoma mansoni calcium-activated potassium channel 0.0019 0.0057 0.0064
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0008 0.001 0.0007
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0019 0.0057 0.0135
Echinococcus granulosus hyperpolarization activated cyclic 0.0019 0.0057 0.0135
Trypanosoma cruzi trypanothione reductase, putative 0.0036 0.0128 0.0258
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0013 0.0031 0.0463
Onchocerca volvulus 0.0033 0.0114 0.1295
Schistosoma mansoni lipoxygenase 0.0029 0.0098 0.0112
Echinococcus multilocularis calcium activated potassium channel 0.002 0.0059 0.014
Brugia malayi Phosphatidylinositol-specific phospholipase C, X domain containing protein 0.0025 0.0079 0.0076
Echinococcus granulosus voltage gated hydrogen channel 1 0.0019 0.0057 0.0135
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0021 0.022
Brugia malayi Variant SH3 domain containing protein 0.003 0.0105 0.0101
Echinococcus multilocularis protein kinase c epsilon type 0.0012 0.0026 0.0057
Loa Loa (eye worm) voltage-dependent calcium channel 0.0019 0.0057 0.0078
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0019 0.0057 0.0961
Echinococcus granulosus 1-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-4 0.0059 0.0229 0.0566
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0007 0.0004 0.000007713
Loa Loa (eye worm) hypothetical protein 0.0032 0.0111 0.0156
Leishmania major DNA polymerase kappa, putative 0.0047 0.0174 0.0525
Toxoplasma gondii transporter, cation channel family protein 0.0019 0.0057 0.0961
Schistosoma mansoni serine/threonine protein kinase 0.0007 0.0004 0.0000036555
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0036 0.0128 0.1927
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0128 0.0258
Trypanosoma brucei unspecified product 0.0032 0.0112 0.0238
Trypanosoma brucei DNA polymerase kappa, putative 0.0047 0.0174 0.037
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0036 0.0128 0.1927
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0036 0.0062
Leishmania major NADH dehydrogenase, putative 0.0013 0.0031 0.0077
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0302 0.0355
Schistosoma mansoni DNA polymerase eta 0.0047 0.0174 0.0203
Loa Loa (eye worm) hypothetical protein 0.0019 0.0057 0.0078
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0019 0.0057 0.0135
Toxoplasma gondii hypothetical protein 0.0019 0.0057 0.0961
Brugia malayi 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 4 0.0057 0.022 0.0216
Trichomonas vaginalis AGC family protein kinase 0.0007 0.0004 0.0022
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0031 0.0052
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0153 0.0629 0.7377
Brugia malayi Protein kinase c protein 2 0.0026 0.0086 0.0082
Trichomonas vaginalis AGC family protein kinase 0.0015 0.0038 0.0426
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0128 0.0258
Echinococcus multilocularis RNA directed DNA polymerase 0.002 0.0061 0.0145
Loa Loa (eye worm) ryanodine receptor 0.0019 0.0057 0.0078
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0075 0.0294 1
Mycobacterium ulcerans DNA polymerase IV 0.0047 0.0174 0.5423
Mycobacterium tuberculosis Conserved hypothetical protein 0.0047 0.0174 0.2836
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0013 0.0031 0.0324
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0012 0.0024 0.0051
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.002 0.0061 0.0145
Onchocerca volvulus 0.0019 0.0057 0.0634
Schistosoma mansoni phospholipase C-like protein 2 plc-L2 0.0051 0.0192 0.0225
Loa Loa (eye worm) hypothetical protein 0.0059 0.0229 0.0327
Loa Loa (eye worm) hypothetical protein 0.0019 0.0057 0.0078
Schistosoma mansoni serine/threonine protein kinase 0.0013 0.003 0.0031
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0047 0.0174 0.2836
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0057 0.0064
Trypanosoma brucei DNA polymerase kappa, putative 0.0047 0.0174 0.037
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0019 0.0057 0.0135
Loa Loa (eye worm) hypothetical protein 0.0019 0.0057 0.0078
Trypanosoma brucei phosphoinositide-specific phospholipase C 0.0039 0.0141 0.0299
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0013 0.0031 0.0463
Plasmodium falciparum thioredoxin reductase 0.0131 0.0534 1
Trichomonas vaginalis AGC family protein kinase 0.0007 0.0004 0.0022
Echinococcus multilocularis transient receptor potential cation channel 0.0019 0.0057 0.0135
Schistosoma mansoni voltage-dependent calcium channel 0.0019 0.0057 0.0064
Trypanosoma brucei NADH dehydrogenase 0.0013 0.0031 0.0066
Echinococcus granulosus lipoxygenase domain containing protein 0.001 0.0018 0.0037
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0019 0.0057 0.0054
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0019 0.0057 0.0135
Trypanosoma brucei DNA polymerase kappa, putative 0.0047 0.0174 0.037
Leishmania major hypothetical protein, conserved 0.0013 0.0031 0.0077
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0019 0.0057 0.0135
Trypanosoma cruzi target of rapamycin kinase 3 0.0012 0.0024 0.0036
Loa Loa (eye worm) hypothetical protein 0.0014 0.0036 0.0047
Echinococcus granulosus protein kinase c epsilon type 0.0012 0.0026 0.0057
Toxoplasma gondii thioredoxin reductase 0.0131 0.0534 1
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0057 0.0064
Schistosoma mansoni serine/threonine protein kinase 0.0012 0.0026 0.0027
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0019 0.0057 0.0064
Trypanosoma brucei DNA damage repair protein, putative 0.0014 0.0036 0.0077
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0013 0.0031 0.0066
Echinococcus multilocularis sodium leak channel non selective protein 0.0019 0.0057 0.0135
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0019 0.0057 0.0159
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0012 0.0026 0.0033
Loa Loa (eye worm) phosphatidylinositol-specific phospholipase C 0.001 0.0018 0.0021
Trypanosoma brucei DNA polymerase IV, putative 0.0047 0.0174 0.037
Leishmania major phosphoinositide-specific phospholipase C, putative 0.0037 0.0132 0.0392
Echinococcus granulosus hypothetical protein 0.0019 0.0057 0.0135
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0031 0.0052
Echinococcus multilocularis tar DNA binding protein 0.0076 0.0302 0.0749
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0019 0.0057 0.0078
Loa Loa (eye worm) glutathione reductase 0.0131 0.0534 0.0771
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0057 0.0064
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0011 0.0022 0.0026
Echinococcus multilocularis glutamate synthase 0.0013 0.0031 0.0069
Trypanosoma cruzi DNA damage repair protein, putative 0.0014 0.0036 0.0062
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0057 0.0064
Trichomonas vaginalis PIKK family atypical protein kinase 0.0009 0.0011 0.0108
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0057 0.0064
Trypanosoma cruzi NADH dehydrogenase, putative 0.0013 0.0031 0.0052
Brugia malayi Phosphatidylinositol-specific phospholipase C, X domain containing protein 0.007 0.0273 0.0269
Leishmania major DNA polymerase eta, putative 0.0014 0.0036 0.0092
Plasmodium vivax glutathione reductase, putative 0.0131 0.0534 1
Schistosoma mansoni lamin 0.0033 0.0114 0.0131
Brugia malayi cytoplasmic intermediate filament protein 0.0017 0.0049 0.0045
Echinococcus granulosus short transient receptor potential channel 6 0.0019 0.0057 0.0135
Echinococcus granulosus potassium voltage gated channel protein 0.0019 0.0057 0.0135
Plasmodium falciparum DNA repair protein REV1, putative 0.0014 0.0036 0.0555
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0019 0.0057 0.0135
Trichomonas vaginalis PIKK family atypical protein kinase 0.0009 0.0015 0.015
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0013 0.003 0.0038
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0036 0.0128 0.0272
Loa Loa (eye worm) RNA binding protein 0.0076 0.0302 0.0433
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0075 0.0294 1
Plasmodium vivax DNA repair protein REV1, putative 0.0014 0.0036 0.0555
Echinococcus multilocularis serine:threonine protein kinase N2 0.0007 0.0004 0.000007713
Toxoplasma gondii AGC kinase 0.0011 0.0022 0.0286
Trichomonas vaginalis mercuric reductase, putative 0.0036 0.0128 0.1484
Loa Loa (eye worm) ion channel NompC 0.0019 0.0057 0.0078
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0023 0.0071 0.0067
Loa Loa (eye worm) hypothetical protein 0.0019 0.0057 0.0078
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0057 0.0064
Echinococcus multilocularis serine:threonine protein kinase N2 0.0007 0.0004 0.000007713
Trypanosoma brucei rac serine-threonine kinase, putative 0.0015 0.0038 0.0081
Echinococcus granulosus protein kinase C gamma type 0.0029 0.01 0.0243
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0015 0.0037 0.0094
Trypanosoma cruzi phosphoinositide-specific phospholipase C, putative 0.0039 0.0141 0.0285
Trypanosoma brucei DNA polymerase kappa, putative 0.0047 0.0174 0.037
Trypanosoma brucei DNA polymerase kappa, putative 0.0047 0.0174 0.037
Loa Loa (eye worm) hypothetical protein 0.0019 0.0057 0.0078
Echinococcus multilocularis dna polymerase kappa 0.0047 0.0174 0.0428
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0057 0.0064
Echinococcus multilocularis cyclin dependent kinase 1 0.0013 0.003 0.0065
Trichomonas vaginalis AGC family protein kinase 0.0015 0.0038 0.0426
Echinococcus granulosus Polycystic kidney disease protein 0.001 0.0018 0.0037
Trypanosoma brucei cdc2-related kinase 3 0.0013 0.003 0.0063
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0013 0.0031 0.0052
Echinococcus multilocularis serine:threonine protein kinase 38 0.0007 0.0004 0.000007713
Echinococcus multilocularis serine threonine protein kinase 0.0029 0.01 0.0243
Plasmodium vivax protein kinase Crk2 0.0013 0.003 0.0433
Schistosoma mansoni terminal deoxycytidyl transferase 0.0047 0.0174 0.0203
Echinococcus multilocularis two pore calcium channel protein 2 0.0019 0.0057 0.0135
Echinococcus granulosus sodium leak channel non selective protein 0.0019 0.0057 0.0135
Mycobacterium ulcerans hypothetical protein 0.0014 0.0036 0.0184
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0036 0.0128 0.0381
Brugia malayi Intermediate filament tail domain containing protein 0.0033 0.0114 0.011
Loa Loa (eye worm) hypothetical protein 0.0019 0.0057 0.0078
Schistosoma mansoni inositol 145-trisphosphate receptor 0.1403 0.599 0.7127
Schistosoma mansoni serine/threonine kinase 0.0007 0.0004 0.0000036555
Loa Loa (eye worm) hypothetical protein 0.1589 0.6785 0.985
Trypanosoma cruzi inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0082 0.0325 0.0678
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0019 0.0057 0.0064
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0013 0.0031 0.0028
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0019 0.0057 0.0135
Brugia malayi Protein kinase domain containing protein 0.0015 0.0038 0.0034
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0019 0.0057 0.0135
Onchocerca volvulus 0.0072 0.0281 0.3269
Entamoeba histolytica PH domain containing protein kinase, putative 0.0008 0.001 0.0078
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0019 0.0057 0.0064
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0024 0.0258
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0013 0.0031 0.0028
Trypanosoma brucei DNA polymerase eta, putative 0.0047 0.0174 0.037
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0019 0.0057 0.0108
Brugia malayi MIR domain containing protein 0.0205 0.0853 0.0849
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0036 0.0128 0.1927
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0013 0.0031 0.0345
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0153 0.0629 0.7377
Loa Loa (eye worm) cytohesin 3 0.0091 0.0364 0.0523
Plasmodium falciparum phosphoinositide-specific phospholipase C 0.0025 0.0079 0.1378
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0047 0.0174 0.2021
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0153 0.0629 0.7377
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0013 0.0031 0.0028
Loa Loa (eye worm) calcium channel 0.0019 0.0057 0.0078
Trypanosoma brucei trypanothione reductase 0.0131 0.0534 0.1136
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0019 0.0057 0.0135
Brugia malayi Phosphatidylinositol-specific phospholipase C, X domain containing protein 0.001 0.0018 0.0015
Echinococcus granulosus geminin 0.0394 0.1665 0.4174
Loa Loa (eye worm) hypothetical protein 0.1613 0.6888 1
Schistosoma mansoni voltage-gated ion channel 0.0019 0.0057 0.0064
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0007 0.0004 0.000007713
Echinococcus granulosus cytohesin 1 0.0091 0.0364 0.0905
Brugia malayi Protein kinase domain containing protein 0.0007 0.0004 0.0000030713
Echinococcus granulosus lamin 0.0033 0.0114 0.0276
Brugia malayi glutamate synthase 0.0013 0.0031 0.0028
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0013 0.003 0.0072
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0019 0.0057 0.0135
Schistosoma mansoni lamin 0.0033 0.0114 0.0131
Treponema pallidum NADH oxidase 0.0036 0.0128 0.162
Echinococcus granulosus TRP transient receptor potential channel 0.0019 0.0057 0.0135
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0036 0.0128 1
Plasmodium falciparum ferrodoxin reductase-like protein 0.0013 0.0031 0.0463
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0014 0.0036 0.0555
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0019 0.0057 0.0135
Echinococcus multilocularis transient receptor potential cation channel 0.0019 0.0057 0.0135
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0015 0.0037 0.0039
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0013 0.0031 0.0345
Trichomonas vaginalis CMGC family protein kinase 0.0013 0.003 0.0326
Leishmania major phospholipase c-like protein 0.0039 0.0141 0.0421
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0029 0.0098 0.0237
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0029 0.0098 0.0237
Leishmania major hypothetical protein, conserved 0.075 0.3189 1
Giardia lamblia DNA damage repair protein 0.0014 0.0036 0.0108
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0057 0.0064
Brugia malayi cell division control protein 2 homolog 0.0013 0.003 0.0026
Brugia malayi RNA recognition motif domain containing protein 0.0076 0.0302 0.0298
Trypanosoma cruzi DNA polymerase kappa, putative 0.0047 0.0174 0.0356
Schistosoma mansoni vesicular amine transporter 0.0019 0.0057 0.0064
Loa Loa (eye worm) hypothetical protein 0.0019 0.0057 0.0078
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0036 0.0128 1
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0016 0.0043 0.0057
Brugia malayi p70 ribosomal S6 kinase beta 0.0011 0.0022 0.0018
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0128 0.0258
Schistosoma mansoni atypical protein kinase C 0.001 0.0017 0.0016
Leishmania major DNA damage repair protein, putative 0.0014 0.0036 0.0092
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0013 0.0031 0.0463
Echinococcus multilocularis ryanodine receptor 44f 0.0936 0.3984 1
Schistosoma mansoni serine/threonine protein kinase 0.0016 0.0043 0.0047
Loa Loa (eye worm) hypothetical protein 0.0019 0.0057 0.0078
Echinococcus multilocularis transient receptor potential cation channel 0.0019 0.0057 0.0135
Trichomonas vaginalis glutathione reductase, putative 0.0036 0.0128 0.1484
Loa Loa (eye worm) hypothetical protein 0.0015 0.0039 0.0051
Trypanosoma brucei unspecified product 0.0032 0.0112 0.0238
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0015 0.0037 0.0387
Echinococcus multilocularis potassium voltage gated channel protein 0.0019 0.0057 0.0135
Loa Loa (eye worm) TAR-binding protein 0.0076 0.0302 0.0433
Brugia malayi Cytohesin 3 0.0091 0.0364 0.036
Loa Loa (eye worm) hypothetical protein 0.0019 0.0057 0.0078
Plasmodium falciparum thioredoxin reductase 0.0036 0.0128 0.23
Echinococcus granulosus glutamate synthase 0.0013 0.0031 0.0069
Echinococcus multilocularis potassium voltage gated channel protein 0.0019 0.0057 0.0135
Schistosoma mansoni serine/threonine-protein kinase 0.0009 0.0013 0.0012
Loa Loa (eye worm) hypothetical protein 0.1403 0.599 0.8695
Trichomonas vaginalis CMGC family protein kinase 0.0013 0.003 0.0326
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0015 0.0037 0.0387
Trypanosoma brucei DNA polymerase kappa, putative 0.0032 0.0112 0.0238
Leishmania major hypothetical protein, conserved 0.0013 0.0031 0.0077
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0019 0.0057 0.0064
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0013 0.0031 0.0345
Toxoplasma gondii selenide, water dikinase 0.0013 0.0031 0.0463
Leishmania major hypothetical protein, conserved 0.0013 0.0031 0.0077
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0019 0.0057 0.0054
Trypanosoma cruzi Protein kinase B 0.0008 0.001 0.0007
Giardia lamblia NADH oxidase lateral transfer candidate 0.0036 0.0128 0.1642
Trypanosoma brucei DNA polymerase kappa, putative 0.0047 0.0174 0.037
Mycobacterium ulcerans DNA polymerase IV 0.0047 0.0174 0.5423
Echinococcus multilocularis ryanodine receptor 44f 0.0726 0.3086 0.7743
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0036 0.0128 0.0381
Echinococcus granulosus calcium activated potassium channel 0.002 0.0059 0.014
Trypanosoma brucei inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0086 0.0341 0.0726
Giardia lamblia Glutamate synthase 0.0013 0.0031 0.0027
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0153 0.0629 0.7377
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0036 0.0128 0.0272
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0016 0.0043 0.0099
Echinococcus granulosus lipoxygenase domain containing protein 0.001 0.0018 0.0037
Loa Loa (eye worm) hypothetical protein 0.0019 0.0057 0.0078
Loa Loa (eye worm) hypothetical protein 0.0033 0.0114 0.016
Trichomonas vaginalis CMGC family protein kinase 0.0013 0.003 0.0326
Echinococcus multilocularis lipoxygenase domain containing protein 0.001 0.0018 0.0037
Schistosoma mansoni sulfide quinone reductase 0.0013 0.0031 0.0033
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0013 0.0031 0.0066
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0057 0.0064
Schistosoma mansoni hypothetical protein 0.0394 0.1665 0.1978
Loa Loa (eye worm) hypothetical protein 0.0082 0.0325 0.0467
Loa Loa (eye worm) voltage-gated potassium channel 0.0019 0.0057 0.0078
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0033 0.0114 0.0276
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0007 0.0058
Trichomonas vaginalis PIKK family atypical protein kinase 0.0008 0.0008 0.007
Trypanosoma cruzi cdc2-related kinase 1 0.0013 0.003 0.0049
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0013 0.0031 0.0345
Echinococcus granulosus potassium voltage gated channel protein 0.0019 0.0057 0.0135
Schistosoma mansoni DNA polymerase IV / kappa 0.0014 0.0036 0.0039
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0037 0.0408
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0019 0.0057 0.0135
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0019 0.0057 0.0135
Trichomonas vaginalis 1-phosphatidylinositol phosphodiesterase, putative 0.001 0.0018 0.0195
Loa Loa (eye worm) phosphatidylinositol-specific phospholipase C 0.007 0.0273 0.0391
Echinococcus granulosus potassium voltage gated channel protein 0.0019 0.0057 0.0135
Echinococcus granulosus serine/threonine protein kinase 0.0008 0.001 0.0017
Loa Loa (eye worm) hypothetical protein 0.0019 0.0057 0.0078
Echinococcus granulosus transient receptor potential gamma protein 0.0019 0.0057 0.0135
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0014 0.0036 0.0555
Onchocerca volvulus 0.0035 0.0122 0.1396
Trypanosoma brucei chrX additional, unordered contigs 0.0014 0.0036 0.0077
Loa Loa (eye worm) thioredoxin reductase 0.0131 0.0534 0.0771
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0024 0.0258
Echinococcus granulosus transient receptor potential cation channel 0.0019 0.0057 0.0135
Giardia lamblia Fructose-bisphosphate aldolase 0.0153 0.0629 1
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.1103 0.4703 1
Schistosoma mansoni glutamate synthase 0.0013 0.0031 0.0033
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0033 0.0114 0.016
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0019 0.0057 0.0064
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0036 0.0128 0.23
Trichomonas vaginalis AGC family protein kinase 0.0015 0.0038 0.0426
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0021 0.022
Plasmodium vivax phospholipase C-like, putative 0.0025 0.0079 0.1378
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0013 0.0031 0.0069
Trichomonas vaginalis PIKK family atypical protein kinase 0.0009 0.0011 0.0112
Echinococcus granulosus transient receptor potential cation channel 0.0019 0.0057 0.0135
Echinococcus multilocularis short transient receptor potential channel 6 0.0019 0.0057 0.0135
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0016 0.0043 0.0057
Onchocerca volvulus 0.0013 0.0031 0.0324
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0015 0.0037 0.0083
Trichomonas vaginalis PIKK family atypical protein kinase 0.0008 0.0008 0.0069
Schistosoma mansoni polycystin 1-related 0.001 0.0018 0.0017
Trypanosoma brucei DNA polymerase kappa, putative 0.0047 0.0174 0.037
Brugia malayi intermediate filament protein 0.0033 0.0114 0.011
Echinococcus multilocularis dna polymerase eta 0.0047 0.0174 0.0428
Echinococcus granulosus ryanodine receptor 44f 0.0936 0.3984 1
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0036 0.0128 0.3684
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0019 0.0057 0.0135
Loa Loa (eye worm) variant SH3 domain-containing protein 0.003 0.0105 0.0147
Entamoeba histolytica deoxycytidyl transferase, putative 0.0047 0.0174 0.2004
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0013 0.0031 0.0027
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0013 0.0031 0.0052
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0019 0.0057 0.0054
Trypanosoma brucei DNA polymerase kappa, putative 0.0047 0.0174 0.037
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0037 0.0408
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0016 0.0043 0.0099
Schistosoma mansoni glutamate synthase 0.0013 0.0031 0.0033
Entamoeba histolytica protein kinase, putative 0.0011 0.0022 0.0214
Loa Loa (eye worm) hypothetical protein 0.0024 0.0075 0.0103
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0036 0.0128 0.3684
Trichomonas vaginalis glutamate synthase, putative 0.0013 0.0031 0.0345
Echinococcus granulosus protein kinase c iota type 0.001 0.0017 0.0034
Echinococcus multilocularis cyclin dependent kinase 0.0013 0.003 0.0065
Echinococcus granulosus voltage dependent calcium channel 0.0019 0.0057 0.0135
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0013 0.0031 0.0052
Echinococcus multilocularis potassium large conductance calcium activated 0.0019 0.0057 0.0135
Trypanosoma cruzi trypanothione reductase, putative 0.0131 0.0534 0.1123
Brugia malayi olfactory channel protein osm-9 0.0019 0.0057 0.0054
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0012 0.0024 0.0054
Loa Loa (eye worm) hypothetical protein 0.0094 0.0377 0.0543
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0019 0.0057 0.0054
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0016 0.0041 0.0095
Brugia malayi Protein kinase domain containing protein 0.0007 0.0004 0.0000030713
Echinococcus granulosus shaker cognate 0.0019 0.0057 0.0135
Trypanosoma brucei unspecified product 0.0047 0.0174 0.037
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0019 0.0057 0.0054
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0019 0.0057 0.0064
Giardia lamblia DINP protein human, muc B family 0.0047 0.0174 0.2404
Schistosoma mansoni serine/threonine protein kinase 0.0007 0.0004 0.0000036555
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0036 0.0128 1
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0019 0.0057 0.0135
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0128 0.0258
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0057 0.0064
Echinococcus granulosus voltage gated potassium channel 0.0019 0.0057 0.0135
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0019 0.0057 0.0135
Trichomonas vaginalis 1-phosphatidylinositol phosphodiesterase, putative 0.001 0.0018 0.0195
Brugia malayi cation channel family protein 0.0019 0.0057 0.0054
Leishmania major DNA polymerase kappa, putative 0.0014 0.0036 0.0092
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0019 0.0057 0.0135
Echinococcus granulosus voltage gated potassium channel 0.0019 0.0057 0.0135
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0036 0.0128 0.0258
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0021 0.022
Loa Loa (eye worm) hypothetical protein 0.0019 0.0057 0.0078
Trypanosoma brucei DNA polymerase IV, putative 0.0047 0.0174 0.037
Echinococcus multilocularis geminin 0.0394 0.1665 0.4174
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0128 0.0258
Brugia malayi ImpB/MucB/SamB family protein 0.0047 0.0174 0.017
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0015 0.0037 0.0063
Trichomonas vaginalis DNA polymerase eta, putative 0.0047 0.0174 0.2021
Loa Loa (eye worm) hypothetical protein 0.0019 0.0057 0.0078
Echinococcus multilocularis lamin dm0 0.0033 0.0114 0.0276
Schistosoma mansoni transient receptor potential channel 0.0019 0.0057 0.0064
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0302 0.0355
Schistosoma mansoni stromal cell-derived factor 2 precursor-like protein 0.0205 0.0853 0.1011
Trichomonas vaginalis apoptosis inducing factor, putative 0.0013 0.0031 0.0345
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0013 0.0031 0.0324
Schistosoma mansoni glutamate synthase 0.0013 0.0031 0.0033
Onchocerca volvulus 0.001 0.0018 0.0172
Schistosoma mansoni hypothetical protein 0.001 0.0018 0.0017
Plasmodium falciparum protein kinase 5 0.0013 0.003 0.0433
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0013 0.0031 0.0345
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.1103 0.4703 1
Brugia malayi Cyclic-nucleotide gated cation channel 0.0019 0.0057 0.0054
Loa Loa (eye worm) Plcb4 protein 0.0057 0.022 0.0314
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0057 0.0064
Echinococcus granulosus RUN 0.001 0.0018 0.0037
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0019 0.0057 0.0064
Plasmodium falciparum glutathione reductase 0.0036 0.0128 0.23
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0013 0.0031 0.0324
Echinococcus multilocularis transient receptor potential cation channel 0.0019 0.0057 0.0135
Echinococcus granulosus voltage dependent calcium channel 0.0019 0.0057 0.0135
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0036 0.0128 0.0381
Echinococcus granulosus NDR protein kinase 0.0007 0.0004 0.000007713
Echinococcus granulosus cyclin dependent kinase 1 0.0013 0.003 0.0065
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0013 0.0031 0.0066
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0013 0.0031 0.0069
Brugia malayi phosphoinositide-dependent protein kinase I 0.0016 0.0043 0.0039
Toxoplasma gondii NADPH-glutathione reductase 0.0036 0.0128 0.23
Entamoeba histolytica PH domain containing protein kinase, putative 0.0008 0.001 0.0078
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0019 0.0057 0.0135
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0036 0.0062
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0153 0.0629 0.7377
Schistosoma mansoni hypothetical protein 0.0013 0.0031 0.0033
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0019 0.0057 0.0634
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0153 0.0629 0.7372
Schistosoma mansoni two-pore calcium channel 0.0019 0.0057 0.0064
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0047 0.0174 0.0525
Leishmania major hypothetical protein, conserved 0.001 0.0018 0.0037
Plasmodium vivax thioredoxin reductase, putative 0.0131 0.0534 1
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0057 0.0064
Echinococcus multilocularis two pore calcium channel protein 1 0.0019 0.0057 0.0135
Echinococcus multilocularis shaker cognate 0.0019 0.0057 0.0135
Trypanosoma brucei CYC2-like cyclin, putative 0.0008 0.0007 0.0014
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0036 0.0077
Entamoeba histolytica protein kinase, putative 0.0015 0.0038 0.0405
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0057 0.0064
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0019 0.0057 0.0064
Plasmodium falciparum glutathione reductase 0.0131 0.0534 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0021 0.022
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.1308 0.5582 0.558
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0019 0.0057 0.0135
Loa Loa (eye worm) AGC/NDR protein kinase 0.0007 0.0004 0.0000044595
Echinococcus multilocularis hyperpolarization activated cyclic 0.0019 0.0057 0.0135
Brugia malayi voltage-dependent calcium channel 0.0019 0.0057 0.0054
Brugia malayi Doublecortin family protein 0.001 0.0018 0.0015
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0007 0.0004 0.000007713
Echinococcus multilocularis transient receptor potential cation channel 0.0019 0.0057 0.0135
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0013 0.0031 0.0324
Loa Loa (eye worm) hypothetical protein 0.0019 0.0057 0.0078
Schistosoma mansoni hypothetical protein 0.0394 0.1665 0.1978
Brugia malayi hypothetical protein 0.001 0.0018 0.0015
Trichomonas vaginalis AGC family protein kinase 0.0016 0.0043 0.0484
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0013 0.0031 0.0069
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0013 0.0031 0.0463
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0128 0.0258
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0013 0.0031 0.0463
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0057 0.0064
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0019 0.0057 0.0135
Echinococcus granulosus thioredoxin glutathione reductase 0.0131 0.0537 0.1341
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0013 0.0031 0.0345
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0019 0.0057 0.0135
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0023 0.0072 0.01
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0013 0.0031 0.0069
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0047 0.0174 0.0203
Loa Loa (eye worm) AGC/PKN protein kinase 0.0007 0.0004 0.0000044595
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0075 0.0294 0.5229
Schistosoma mansoni serine/threonine-protein kinase 0.0008 0.001 0.0008
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0019 0.0057 0.0054
Schistosoma mansoni 60S ribosomal protein L21 0.0019 0.0057 0.0064
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0036 0.0128 0.0272
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0013 0.003 0.0065
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0013 0.0031 0.0077
Brugia malayi polk-prov protein 0.0014 0.0036 0.0032
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0076 0.0302 0.0433
Loa Loa (eye worm) hypothetical protein 0.0019 0.0057 0.0078
Echinococcus granulosus Protein kinase C brain isozyme 0.0033 0.0114 0.0276
Schistosoma mansoni transient receptor potential channel 4 0.0019 0.0057 0.0064
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0036 0.0128 0.23
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0007 0.0004 0.0000044595
Giardia lamblia Thioredoxin reductase 0.0013 0.0031 0.0027
Echinococcus granulosus transient receptor potential cation channel 0.0019 0.0057 0.0135
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0007 0.0004 0.000007713
Giardia lamblia GTOR 0.0015 0.0037 0.0116
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0019 0.0057 0.0064
Echinococcus granulosus RNA directed DNA polymerase 0.002 0.0061 0.0145
Echinococcus granulosus cyclin dependent kinase 5 0.0013 0.003 0.0065
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0036 0.0128 0.0381
Onchocerca volvulus 0.0205 0.0853 1
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0019 0.0057 0.0064
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0015 0.0037 0.0078
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0024 0.0258
Loa Loa (eye worm) phosphatidylinositol 3 0.0015 0.0037 0.0048
Schistosoma mansoni intermediate filament proteins 0.0033 0.0114 0.0131
Schistosoma mansoni serine/threonine protein kinase 0.0007 0.0004 0.0000036555
Trichomonas vaginalis AGC family protein kinase 0.0007 0.0004 0.0022
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0019 0.0057 0.0634
Echinococcus multilocularis short transient receptor potential channel 6 0.0019 0.0057 0.0135
Brugia malayi phospholipase C homolog 0.0016 0.0044 0.0041
Loa Loa (eye worm) hypothetical protein 0.001 0.0018 0.0021
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0013 0.0031 0.0345
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0019 0.0057 0.0135
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0019 0.0057 0.0064
Brugia malayi Protein kinase domain containing protein 0.0013 0.003 0.0026
Loa Loa (eye worm) hypothetical protein 0.0016 0.0041 0.0055
Echinococcus granulosus two pore calcium channel protein 2 0.0019 0.0057 0.0135
Brugia malayi hypothetical protein 0.001 0.0018 0.0015
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0036 0.0128 0.0313
Echinococcus multilocularis transient receptor potential cation channel 0.0019 0.0057 0.0135
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0047 0.0174 0.0428
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0021 0.022
Brugia malayi ion channel NompC 0.0019 0.0057 0.0054
Echinococcus multilocularis hyperpolarization activated cyclic 0.0019 0.0057 0.0135
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0015 0.0037 0.0063
Trypanosoma cruzi DNA damage repair protein, putative 0.0014 0.0036 0.0062
Trypanosoma cruzi NADH dehydrogenase, putative 0.0013 0.0031 0.0052
Brugia malayi Hr1 repeat family protein 0.0007 0.0004 0.0000030713
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0024 0.0258
Echinococcus multilocularis voltage gated potassium channel 0.0019 0.0057 0.0135
Loa Loa (eye worm) hypothetical protein 0.0019 0.0057 0.0078
Loa Loa (eye worm) hypothetical protein 0.0013 0.0028 0.0035
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0021 0.022
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0013 0.003 0.0038
Trypanosoma cruzi DNA polymerase kappa, putative 0.0047 0.0174 0.0356
Trypanosoma brucei glycosylphosphatidylinositol-specific phospholipase C 0.001 0.0018 0.0039
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0153 0.0629 0.7377
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0013 0.0031 0.0077
Loa Loa (eye worm) hypothetical protein 0.0019 0.0057 0.0078
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0013 0.0031 0.0066
Echinococcus granulosus transient receptor potential cation channel 0.0019 0.0057 0.0135
Echinococcus multilocularis microtubule associated protein 2 0.0361 0.1522 0.3814
Leishmania major hypothetical protein, unknown function 0.0019 0.0057 0.0159
Trichomonas vaginalis AGC family protein kinase 0.0015 0.0038 0.0426
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0015 0.0037 0.0033
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0019 0.0057 0.0054
Loa Loa (eye worm) MIR domain-containing protein 0.0205 0.0853 0.1233
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0007 0.0004 0.000007713
Trichomonas vaginalis PIKK family atypical protein kinase 0.0008 0.0008 0.007
Brugia malayi phospholipase C homolog 0.0043 0.0159 0.0155
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0036 0.0128 0.0272
Trypanosoma cruzi DNA polymerase eta, putative 0.0014 0.0036 0.0062
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0013 0.0031 0.0069
Trichomonas vaginalis AGC family protein kinase 0.0015 0.0038 0.0426
Entamoeba histolytica cell division protein kinase 2, putative 0.0013 0.003 0.0305
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0302 0.0355
Trypanosoma brucei cyclin 2 0.0008 0.0007 0.0014
Echinococcus granulosus intermediate filament protein 0.0033 0.0114 0.0276
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0036 0.0077
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0019 0.0057 0.0135
Brugia malayi Protein kinase domain containing protein 0.0016 0.0043 0.0039
Schistosoma mansoni serine/threonine protein kinase 0.0033 0.0114 0.0131
Loa Loa (eye worm) hypothetical protein 0.002 0.0061 0.0084
Onchocerca volvulus 0.001 0.0018 0.0174
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0013 0.0031 0.0069
Entamoeba histolytica protein kinase, putative 0.0016 0.0043 0.0463
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0019 0.0057 0.0054
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0019 0.0057 0.0054
Plasmodium vivax multidomain scavenger receptor, putative 0.001 0.0018 0.0218
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0013 0.0031 0.0463
Leishmania major phosphatidylinositol-specific phospholipase-like protein 0.0025 0.0079 0.0228
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0302 0.0355
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0019 0.0057 0.0064
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0036 0.0128 0.23
Echinococcus multilocularis lamin 0.0033 0.0114 0.0276
Trichomonas vaginalis AGC family protein kinase 0.0015 0.0038 0.0426
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0007 0.0004 0.0000044595
Schistosoma mansoni serine/threonine protein kinase 0.0033 0.0114 0.0131
Trypanosoma cruzi DNA polymerase kappa, putative 0.0047 0.0174 0.0356
Echinococcus multilocularis stromal cell derived factor 2 0.0205 0.0853 0.2133
Brugia malayi glutathione reductase 0.0131 0.0534 0.0531
Echinococcus granulosus cyclin dependent kinase 0.0013 0.003 0.0065
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0036 0.0128 0.23
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0019 0.0057 0.0122
Loa Loa (eye worm) hypothetical protein 0.0936 0.3984 0.5782
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0019 0.0057 0.0135
Trypanosoma cruzi inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0082 0.0325 0.0678
Trypanosoma cruzi cdc2-related kinase 3 0.0013 0.003 0.0049
Toxoplasma gondii phosphoinositide phospholipase PIPLC 0.0058 0.0221 0.4055
Schistosoma mansoni phospholipase C beta 0.0057 0.022 0.0257
Trichomonas vaginalis AGC family protein kinase 0.0011 0.002 0.0212
Plasmodium falciparum LCCL domain-containing protein 0.001 0.0018 0.0218
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0036 0.0128 0.3684
Echinococcus multilocularis voltage gated potassium channel 0.0019 0.0057 0.0135
Onchocerca volvulus 0.0102 0.0413 0.4825
Trichomonas vaginalis AGC family protein kinase 0.0015 0.0038 0.0426
Onchocerca volvulus 0.0033 0.0114 0.1295
Echinococcus multilocularis Polycystic kidney disease protein 0.001 0.0018 0.0037
Schistosoma mansoni ryanodine receptor 1 skeletal muscle 0.0353 0.1488 0.1768
Echinococcus granulosus potassium voltage gated channel protein 0.0019 0.0057 0.0135
Schistosoma mansoni transient receptor potential channel 0.0019 0.0057 0.0064
Echinococcus multilocularis lipoxygenase domain containing protein 0.001 0.0018 0.0037
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0036 0.0128 0.0313
Echinococcus multilocularis cyclin dependent kinase 1 0.0013 0.003 0.0065
Plasmodium vivax ferrodoxin reductase, putative 0.0013 0.0031 0.0463
Echinococcus granulosus hyperpolarization activated cyclic 0.0019 0.0057 0.0135
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0019 0.0057 0.0064
Trypanosoma cruzi DNA polymerase kappa, putative 0.0047 0.0174 0.0356
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0036 0.0128 0.0258
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0057 0.0064
Loa Loa (eye worm) intermediate filament protein 0.0033 0.0114 0.016
Loa Loa (eye worm) programmed cell death 8 0.0013 0.0031 0.004
Echinococcus granulosus two pore calcium channel protein 1 0.0019 0.0057 0.0135
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0015 0.0037 0.0083
Echinococcus granulosus ryanodine receptor 44f 0.0726 0.3086 0.7743
Echinococcus multilocularis sodium channel protein 0.0019 0.0057 0.0135
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0013 0.0031 0.0345
Schistosoma mansoni microtubule-associated protein tau 0.0361 0.1522 0.1807
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0057 0.0064
Trichomonas vaginalis AGC family protein kinase 0.0016 0.0043 0.0484
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0019 0.0057 0.0135
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0013 0.0031 0.0069
Trypanosoma cruzi cdc2-related kinase 1 0.0013 0.003 0.0049
Echinococcus granulosus tar DNA binding protein 0.0076 0.0302 0.0749
Trichomonas vaginalis PIKK family atypical protein kinase 0.0008 0.0008 0.0069
Trypanosoma brucei DNA polymerase kappa, putative 0.0047 0.0174 0.037
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0019 0.0057 0.0054
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0013 0.0031 0.0069
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0024 0.0258
Trypanosoma brucei cdc2-related kinase 1 0.0013 0.003 0.0063
Brugia malayi ImpB/MucB/SamB family protein 0.0047 0.0174 0.017
Trichomonas vaginalis PIKK family atypical protein kinase 0.0009 0.0011 0.0112
Trypanosoma brucei DNA polymerase kappa, putative 0.0047 0.0174 0.037
Brugia malayi RNA binding protein 0.0076 0.0302 0.0298
Entamoeba histolytica protein kinase, putative 0.0015 0.0038 0.0405
Trypanosoma brucei DNA polymerase kappa, putative 0.0032 0.0112 0.0238
Schistosoma mansoni disulfide oxidoreductase 0.0013 0.0031 0.0033
Toxoplasma gondii transporter, cation channel family protein 0.0019 0.0057 0.0961
Schistosoma mansoni inositol 145-trisphosphate receptor 0.1966 0.8402 1
Echinococcus multilocularis transfer RNA-Gly 0.0019 0.0057 0.0135
Echinococcus multilocularis voltage dependent calcium channel 0.0019 0.0057 0.0135
Trichomonas vaginalis mannosyltransferase 1, putative 0.0205 0.0853 1
Trypanosoma brucei hypothetical protein, conserved 0.0013 0.0031 0.0066
Echinococcus granulosus serine:threonine protein kinase N2 0.0007 0.0004 0.000007713
Entamoeba histolytica disulphide oxidoreductase, putative 0.0013 0.0031 0.0324
Trypanosoma cruzi DNA polymerase eta, putative 0.0047 0.0174 0.0356
Echinococcus granulosus transient receptor potential cation channel 0.0019 0.0057 0.0135
Trypanosoma brucei hypothetical protein, conserved 0.0014 0.0036 0.0077
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0019 0.0057 0.0135
Echinococcus granulosus dna polymerase eta 0.0047 0.0174 0.0428
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0153 0.0629 0.7377
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0019 0.0057 0.0064
Echinococcus multilocularis cytohesin 1 0.0091 0.0364 0.0905
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0019 0.0057 0.0054
Echinococcus multilocularis musashi 0.0033 0.0114 0.0276
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0013 0.003 0.0038
Loa Loa (eye worm) voltage-gated calcium channel 0.0019 0.0057 0.0078
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0013 0.0031 0.0324
Trichomonas vaginalis PIKK family atypical protein kinase 0.0008 0.0008 0.007
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0013 0.0031 0.0069
Leishmania major DNA polymerase eta, putative 0.0047 0.0174 0.0525
Trypanosoma brucei DNA damage repair protein, putative 0.0014 0.0036 0.0077
Entamoeba histolytica MIR domain protein 0.0205 0.0853 1
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0013 0.0031 0.0463
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0019 0.0057 0.0135
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0013 0.0031 0.0345
Schistosoma mansoni phospholipase C beta 0.001 0.0018 0.0018
Brugia malayi Transient-receptor-potential like protein 0.0019 0.0057 0.0054
Echinococcus granulosus potassium large conductance calcium activated 0.0019 0.0057 0.0135
Onchocerca volvulus 0.001 0.0018 0.0172
Trichomonas vaginalis PIKK family atypical protein kinase 0.001 0.0016 0.0166
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0013 0.0031 0.0463
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0131 0.0534 1
Trichomonas vaginalis glutamate synthase, putative 0.0013 0.0031 0.0345
Echinococcus multilocularis cyclin dependent kinase 5 0.0013 0.003 0.0065
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0019 0.0057 0.0654
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0057 0.0064
Loa Loa (eye worm) hypothetical protein 0.0035 0.0122 0.0172
Schistosoma mansoni rab6-interacting 0.001 0.0018 0.0017
Schistosoma mansoni lipoxygenase 0.001 0.0018 0.0017
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0014 0.0036 0.0555
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0007 0.0004 0.0000044595
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0015 0.0037 0.0094
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0023 0.0071 0.0067
Schistosoma mansoni serine/threonine protein kinase 0.0007 0.0004 0.0000036555
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0036 0.0128 0.3684
Echinococcus granulosus microtubule associated protein 2 0.0361 0.1522 0.3814
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0013 0.0031 0.0069
Echinococcus multilocularis rac serine:threonine kinase 0.0008 0.001 0.0017
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0013 0.003 0.0072
Schistosoma mansoni phospholipase C-like protein 2 plc-L2 0.0043 0.0159 0.0185
Trypanosoma brucei DNA polymerase kappa, putative 0.0032 0.0112 0.0238
Leishmania major trypanothione reductase 0.0131 0.0534 0.1657
Loa Loa (eye worm) hypothetical protein 0.0019 0.0057 0.0078
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0007 0.0004 0.000007713
Toxoplasma gondii transporter, cation channel family protein 0.0019 0.0057 0.0961
Brugia malayi TAR-binding protein 0.0076 0.0302 0.0298
Trichomonas vaginalis AGC family protein kinase 0.0016 0.0043 0.0484
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0013 0.0031 0.0069
Echinococcus granulosus potassium voltage gated channel protein 0.0019 0.0057 0.0135
Brugia malayi Thioredoxin reductase 0.0131 0.0534 0.0531
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0015 0.0037 0.0078
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0027 0.0301
Echinococcus granulosus short transient receptor potential channel 6 0.0019 0.0057 0.0135
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0019 0.0057 0.0654
Leishmania major inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0082 0.0325 0.1
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0019 0.0057 0.0054
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0017 0.0049 0.0066
Trichomonas vaginalis PIKK family atypical protein kinase 0.0008 0.0008 0.007

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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