Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.023 | 0.1739 | 0.3696 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0435 | 0.4704 | 1 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0435 | 0.4704 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0435 | 0.4704 | 1 |
Brugia malayi | nuclear receptor NHR-88 | 0.0435 | 0.4704 | 1 |
Brugia malayi | hypothetical protein | 0.0205 | 0.1383 | 0.294 |
Brugia malayi | Pre-SET motif family protein | 0.0251 | 0.205 | 0.4358 |
Schistosoma mansoni | thyroid hormone receptor | 0.0435 | 0.4704 | 0.4704 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0435 | 0.4704 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0435 | 0.4704 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0435 | 0.4704 | 0.4704 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0435 | 0.4704 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0123 | 0.0188 | 0.0188 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0435 | 0.4704 | 0.4704 |
Schistosoma mansoni | hypothetical protein | 0.0205 | 0.1375 | 0.1375 |
Loa Loa (eye worm) | hypothetical protein | 0.0435 | 0.4704 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.023 | 0.1739 | 0.3696 |
Echinococcus multilocularis | expressed protein | 0.0433 | 0.4682 | 0.4682 |
Brugia malayi | conserved hypotetical protein | 0.0205 | 0.1383 | 0.294 |
Onchocerca volvulus | 0.0435 | 0.4704 | 1 | |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0435 | 0.4704 | 1 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0205 | 0.1383 | 0.1383 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0435 | 0.4704 | 1 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0435 | 0.4704 | 0.4704 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0435 | 0.4704 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0435 | 0.4704 | 1 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0435 | 0.4704 | 0.4704 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0435 | 0.4704 | 0.4704 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0205 | 0.1383 | 0.294 |
Brugia malayi | hypothetical protein | 0.0205 | 0.1383 | 0.294 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0435 | 0.4704 | 0.4704 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0205 | 0.1383 | 0.1383 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0435 | 0.4704 | 0.4704 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0205 | 0.1383 | 0.294 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0435 | 0.4704 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0435 | 0.4704 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0435 | 0.4704 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.023 | 0.1739 | 0.3696 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0205 | 0.1383 | 0.1383 |
Schistosoma mansoni | nuclear hormone receptor | 0.0435 | 0.4704 | 0.4704 |
Brugia malayi | hypothetical protein | 0.023 | 0.1739 | 0.3696 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0435 | 0.4704 | 1 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0435 | 0.4704 | 0.4704 |
Brugia malayi | ecdysteroid receptor | 0.0435 | 0.4704 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0205 | 0.1383 | 0.294 |
Loa Loa (eye worm) | hypothetical protein | 0.0205 | 0.1383 | 0.294 |
Loa Loa (eye worm) | hypothetical protein | 0.0205 | 0.1383 | 0.294 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0435 | 0.4704 | 0.4704 |
Schistosoma mansoni | nuclear receptor | 0.0205 | 0.1383 | 0.1383 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0435 | 0.4704 | 0.4704 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0205 | 0.1383 | 0.1383 |
Loa Loa (eye worm) | hypothetical protein | 0.0435 | 0.4704 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0205 | 0.1383 | 0.294 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0435 | 0.4704 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0435 | 0.4704 | 1 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0435 | 0.4704 | 0.4704 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0205 | 0.1383 | 0.1383 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0205 | 0.1383 | 0.1383 |
Loa Loa (eye worm) | hypothetical protein | 0.023 | 0.1739 | 0.3696 |
Brugia malayi | nuclear hormone receptor | 0.0205 | 0.1383 | 0.294 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0205 | 0.1383 | 0.294 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0435 | 0.4704 | 0.4704 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0205 | 0.1383 | 0.294 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0205 | 0.1383 | 0.294 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0435 | 0.4704 | 0.4704 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.023 | 0.1739 | 0.1739 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0435 | 0.4704 | 0.4704 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0435 | 0.4704 | 0.4704 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0435 | 0.4704 | 0.4704 |
Schistosoma mansoni | thyroid hormone receptor | 0.0435 | 0.4704 | 0.4704 |
Loa Loa (eye worm) | hypothetical protein | 0.023 | 0.1739 | 0.3696 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.023 | 0.1739 | 0.1739 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0435 | 0.4704 | 0.4704 |
Schistosoma mansoni | zinc finger protein | 0.0205 | 0.1383 | 0.1383 |
Echinococcus granulosus | FTZ F1 alpha | 0.0435 | 0.4704 | 0.4704 |
Trichomonas vaginalis | set domain proteins, putative | 0.0286 | 0.2552 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0435 | 0.4704 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0205 | 0.1383 | 0.1383 |
Schistosoma mansoni | nuclear receptor | 0.0205 | 0.1383 | 0.1383 |
Loa Loa (eye worm) | hypothetical protein | 0.0205 | 0.1383 | 0.294 |
Loa Loa (eye worm) | hypothetical protein | 0.0435 | 0.4704 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0435 | 0.4704 | 1 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0435 | 0.4704 | 0.4704 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0435 | 0.4704 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0435 | 0.4704 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0205 | 0.1383 | 0.294 |
Schistosoma mansoni | nuclear hormone receptor | 0.0205 | 0.1383 | 0.1383 |
Treponema pallidum | sodium- and chloride- dependent transporter | 0.0109 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0205 | 0.1375 | 0.1375 |
Brugia malayi | nuclear receptor RXR | 0.0205 | 0.1383 | 0.294 |
Brugia malayi | nuclear receptor RXR | 0.023 | 0.1739 | 0.3696 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0435 | 0.4704 | 0.4704 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0435 | 0.4704 | 1 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0205 | 0.1383 | 0.1383 |
Loa Loa (eye worm) | hypothetical protein | 0.0205 | 0.1383 | 0.294 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0435 | 0.4704 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0435 | 0.4704 | 1 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0435 | 0.4704 | 0.4704 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0205 | 0.1383 | 0.1383 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0205 | 0.1383 | 0.294 |
Loa Loa (eye worm) | DR-78 | 0.0205 | 0.1383 | 0.294 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.023 | 0.1739 | 0.3696 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0435 | 0.4704 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0435 | 0.4704 | 1 |
Brugia malayi | steroid hormone receptor | 0.0435 | 0.4704 | 1 |
Brugia malayi | nuclear receptor NHR-88 | 0.0205 | 0.1383 | 0.294 |
Loa Loa (eye worm) | hypothetical protein | 0.0205 | 0.1383 | 0.294 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0205 | 0.1383 | 0.1383 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0801 | 1 | 1 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0435 | 0.4704 | 1 |
Onchocerca volvulus | 0.0286 | 0.2552 | 0.5425 | |
Schistosoma mansoni | nuclear hormone receptor | 0.0205 | 0.1383 | 0.1383 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0251 | 0.205 | 0.4358 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0205 | 0.1383 | 0.1383 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0435 | 0.4704 | 0.4704 |
Loa Loa (eye worm) | hypothetical protein | 0.0435 | 0.4704 | 1 |
Echinococcus multilocularis | geminin | 0.0205 | 0.1375 | 0.1375 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0435 | 0.4704 | 0.4704 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0435 | 0.4704 | 1 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0435 | 0.4704 | 0.4704 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0435 | 0.4704 | 0.4704 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0435 | 0.4704 | 0.4704 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0205 | 0.1383 | 0.1383 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0205 | 0.1383 | 0.294 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0435 | 0.4704 | 1 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0801 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.023 | 0.1739 | 0.3696 |
Echinococcus granulosus | expressed protein | 0.0433 | 0.4682 | 0.4682 |
Brugia malayi | ecdysone receptor | 0.0205 | 0.1383 | 0.294 |
Onchocerca volvulus | 0.0205 | 0.1383 | 0.294 | |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0205 | 0.1383 | 0.1383 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0205 | 0.1383 | 0.294 |
Onchocerca volvulus | 0.0205 | 0.1383 | 0.294 | |
Loa Loa (eye worm) | hypothetical protein | 0.023 | 0.1739 | 0.3696 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.023 | 0.1739 | 0.1739 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0205 | 0.1383 | 0.1383 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0205 | 0.1383 | 0.294 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0205 | 0.1383 | 0.1383 |
Loa Loa (eye worm) | hypothetical protein | 0.0205 | 0.1383 | 0.294 |
Echinococcus granulosus | geminin | 0.0205 | 0.1375 | 0.1375 |
Loa Loa (eye worm) | hypothetical protein | 0.0435 | 0.4704 | 1 |
Brugia malayi | nuclear hormone receptor | 0.0435 | 0.4704 | 1 |
Brugia malayi | nuclear receptor NHR-67 | 0.0205 | 0.1383 | 0.294 |
Schistosoma mansoni | coup transcription factor | 0.0435 | 0.4704 | 0.4704 |
Brugia malayi | tailless protein | 0.0205 | 0.1383 | 0.294 |
Loa Loa (eye worm) | hypothetical protein | 0.0435 | 0.4704 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0205 | 0.1383 | 0.294 |
Loa Loa (eye worm) | hypothetical protein | 0.0205 | 0.1383 | 0.294 |
Brugia malayi | hypothetical protein | 0.023 | 0.1739 | 0.3696 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0205 | 0.1383 | 0.294 |
Loa Loa (eye worm) | hypothetical protein | 0.0205 | 0.1383 | 0.294 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0435 | 0.4704 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0205 | 0.1383 | 0.294 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0435 | 0.4704 | 0.4704 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0205 | 0.1383 | 0.294 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.023 | 0.1739 | 0.1739 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.