Detailed information for compound 2069315

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 328.384 | Formula: C18H21FN4O
  • H donors: 1 H acceptors: 3 LogP: 2.31 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: Fc1cccc(c1)CC(=O)N1CCC(CC1)Nc1ccc(nn1)C
  • InChi: 1S/C18H21FN4O/c1-13-5-6-17(22-21-13)20-16-7-9-23(10-8-16)18(24)12-14-3-2-4-15(19)11-14/h2-6,11,16H,7-10,12H2,1H3,(H,20,22)
  • InChiKey: QZAFWZXAZDUMMP-UHFFFAOYSA-N  


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Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0063 0.036 0.0551
Loa Loa (eye worm) hypothetical protein 0.002 0.0033 0.0051
Brugia malayi putative neuropeptide receptor NPR1 0.0063 0.036 0.0551
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0099 0.0636 0.2328
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0032 0.0122 0.0435
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0063 0.036 0.1074
Leishmania major cytochrome p450-like protein 0.0032 0.0122 0.0122
Trypanosoma brucei protein kinase, putative 0.0056 0.0306 0.0306
Loa Loa (eye worm) hypothetical protein 0.003 0.0111 0.0169
Echinococcus granulosus rhodopsin orphan GPCR 0.0063 0.036 0.0471
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.004 0.0188 0.0289
Loa Loa (eye worm) hypothetical protein 0.0042 0.02 0.0306
Entamoeba histolytica hypothetical protein 0.0023 0.0056 0.0221
Mycobacterium ulcerans DNA gyrase subunit A 0.0066 0.0381 0.1389
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0063 0.036 0.0471
Trypanosoma brucei heat shock protein, putative 0.0016 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0029
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0096 0.0096
Brugia malayi hypothetical protein 0.0063 0.036 0.0551
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0032 0.0122 0.0353
Echinococcus granulosus FTZ F1 alpha 0.0027 0.0091 0.012
Entamoeba histolytica hypothetical protein 0.0017 0.0015 0.0046
Toxoplasma gondii DNA topoisomerase 2, putative 0.0324 0.2338 0.6982
Echinococcus multilocularis lamin dm0 0.0043 0.0206 0.027
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0324 0.2338 0.2338
Toxoplasma gondii heat shock protein 90, putative 0.0016 0.0004 0.0012
Leishmania major heat shock protein 83-1 0.0016 0.0004 0.0004
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0082 0.0507 0.1513
Trichomonas vaginalis set domain proteins, putative 0.1 0.7446 1
Loa Loa (eye worm) intermediate filament protein 0.0043 0.0206 0.0315
Echinococcus multilocularis rhodopsin orphan GPCR 0.0063 0.036 0.0471
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0063 0.036 0.0471
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0032 0.0122 0.0353
Trichomonas vaginalis glucosylceramidase, putative 0.0289 0.2067 0.2776
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0027 0.0091 0.014
Schistosoma mansoni lamin 0.0043 0.0206 0.0615
Plasmodium falciparum importin beta, putative 0.0028 0.0096 0.0286
Loa Loa (eye worm) hypothetical protein 0.0544 0.3996 0.6121
Brugia malayi Dopamine receptor protein 2 0.0063 0.036 0.0551
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0086 0.0532 0.0532
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0063 0.036 0.0551
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0247 0.1755 0.1755
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0021 0.0039 0.0052
Trichomonas vaginalis glutamate synthase, putative 0.0099 0.0636 0.0854
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0056 0.0306 0.0306
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0551
Echinococcus multilocularis rhodopsin orphan GPCR 0.0063 0.036 0.0471
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0063 0.036 0.0551
Plasmodium vivax DNA gyrase subunit B, putative 0.0082 0.0507 0.1513
Brugia malayi Carboxylesterase family protein 0.003 0.0111 0.0169
Loa Loa (eye worm) heat shock protein 90 0.0016 0.0004 0.0006
Echinococcus multilocularis serotonin receptor 0.0063 0.036 0.0471
Loa Loa (eye worm) hypothetical protein 0.002 0.0033 0.0051
Echinococcus granulosus neuropeptides capa receptor 0.0063 0.036 0.0471
Echinococcus multilocularis G-protein coupled receptor, putative 0.0063 0.036 0.0471
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0551
Onchocerca volvulus 0.0018 0.0019 0.0025
Mycobacterium tuberculosis Probable dehydrogenase 0.0099 0.0636 0.189
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0063 0.036 0.1074
Brugia malayi Protein kinase domain containing protein 0.0017 0.0009 0.0014
Brugia malayi G protein-coupled receptor 0.0063 0.036 0.0551
Echinococcus multilocularis neuropeptides capa receptor 0.0063 0.036 0.0471
Echinococcus granulosus heat shock protein 90 0.0016 0.0004 0.0005
Brugia malayi MAP kinase sur-1 0.0056 0.0306 0.0469
Loa Loa (eye worm) hypothetical protein 0.0028 0.0096 0.0147
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0375 0.2719 0.8119
Loa Loa (eye worm) carboxylesterase 0.0178 0.1228 0.188
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0032 0.0122 0.0122
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0375 0.2719 0.8121
Echinococcus granulosus importin subunit beta 1 0.0028 0.0096 0.0125
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0375 0.2719 0.4165
Brugia malayi glutamate synthase 0.0099 0.0636 0.0974
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0063 0.036 0.0471
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0551
Schistosoma mansoni alpha-1 adrenergic receptor 0.0063 0.036 0.1074
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0551
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0324 0.2338 0.3581
Entamoeba histolytica disulphide oxidoreductase, putative 0.0099 0.0636 0.2708
Onchocerca volvulus 0.0063 0.036 0.0483
Trypanosoma cruzi Heat shock protein 83, putative 0.0016 0.0004 0.0004
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0099 0.0636 0.189
Trypanosoma cruzi DNA topoisomerase II, putative 0.0324 0.2338 0.2338
Brugia malayi hypothetical protein 0.0063 0.036 0.0551
Trypanosoma cruzi trypanothione reductase, putative 0.0375 0.2719 0.2719
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0375 0.2719 1
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0061 0.0344 0.0451
Brugia malayi G protein-coupled receptor F59B2.13 0.0063 0.036 0.0551
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0021 0.0039 0.0117
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0099 0.0636 0.19
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0099 0.0636 0.2328
Loa Loa (eye worm) hypothetical protein 0.0016 0.0006 0.0009
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0551
Brugia malayi Augmenter of liver regeneration 0.0061 0.0344 0.0528
Echinococcus multilocularis G protein coupled receptor 139 0.0063 0.036 0.0471
Onchocerca volvulus Glucosylceramidase homolog 0.0189 0.1316 0.1767
Trichomonas vaginalis glucosylceramidase, putative 0.0189 0.1316 0.1768
Brugia malayi neuropeptide F receptor 0.0063 0.036 0.0551
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0032 0.0122 0.0435
Brugia malayi hypothetical protein 0.0063 0.036 0.0551
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0324 0.2338 0.2338
Brugia malayi Cytochrome P450 family protein 0.0041 0.0195 0.0298
Loa Loa (eye worm) hypothetical protein 0.0027 0.0091 0.014
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0029
Onchocerca volvulus 0.0063 0.036 0.0483
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0027 0.0091 0.012
Schistosoma mansoni hypothetical protein 0.0063 0.036 0.1074
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.004 0.0118
Giardia lamblia NADH oxidase lateral transfer candidate 0.0375 0.2719 1
Loa Loa (eye worm) hypothetical protein 0.0077 0.0466 0.0715
Mycobacterium tuberculosis Probable oxidoreductase 0.0375 0.2719 0.8119
Plasmodium vivax SET domain protein, putative 0.0126 0.0837 0.2499
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.003 0.0111 0.033
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0061 0.0344 0.0344
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0018 0.0019 0.0024
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0099 0.0636 0.0974
Echinococcus multilocularis serotonin transporter 0.0105 0.068 0.0891
Loa Loa (eye worm) hypothetical protein 0.0178 0.1228 0.188
Echinococcus granulosus sex peptide receptor 0.0063 0.036 0.0471
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0063 0.036 0.0551
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0027 0.0091 0.0273
Echinococcus multilocularis mitogen activated protein kinase 0.0056 0.0306 0.0401
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0029
Toxoplasma gondii DNA gyrase/topoisomerase IV, A subunit domain-containing protein 0.0066 0.0381 0.1138
Trypanosoma brucei heat shock protein, putative 0.0016 0.0004 0.0004
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0375 0.2719 0.2719
Brugia malayi Probable DNA topoisomerase II 0.0324 0.2338 0.3581
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0099 0.0636 0.0854
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0063 0.036 0.1074
Mycobacterium ulcerans carboxylesterase, LipT 0.003 0.0111 0.0393
Onchocerca volvulus 0.0063 0.036 0.0483
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0027 0.0091 0.012
Toxoplasma gondii selenide, water dikinase 0.0099 0.0636 0.19
Trypanosoma brucei NADH dehydrogenase 0.0099 0.0636 0.0636
Schistosoma mansoni biogenic amine receptor 0.0063 0.036 0.1074
Schistosoma mansoni hypothetical protein 0.0063 0.036 0.1074
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0032 0.0122 0.0435
Schistosoma mansoni neuropeptide F-like receptor 0.0063 0.036 0.1074
Schistosoma mansoni cytochrome P450 0.0032 0.0122 0.0364
Echinococcus multilocularis heat shock protein 0.0016 0.0004 0.0005
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0063 0.036 0.0471
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0099 0.0636 0.19
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0099 0.0636 0.19
Schistosoma mansoni RAR-like nuclear receptor 0.0027 0.0091 0.0273
Schistosoma mansoni importin beta-1 0.0028 0.0096 0.0286
Echinococcus multilocularis FTZ F1 alpha 0.0027 0.0091 0.012
Echinococcus granulosus heat shock protein 0.0016 0.0004 0.0005
Echinococcus multilocularis serotonin receptor 0.0063 0.036 0.0471
Trichomonas vaginalis glucosylceramidase, putative 0.0289 0.2067 0.2776
Echinococcus granulosus allatostatin A receptor 0.0063 0.036 0.0471
Mycobacterium leprae Conserved hypothetical protein 0.0032 0.0122 0.0435
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0027 0.0091 0.014
Trypanosoma cruzi DNA topoisomerase II, putative 0.0324 0.2338 0.2338
Schistosoma mansoni heat shock protein 0.0016 0.0004 0.0012
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0018 0.0019 0.0056
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0099 0.0636 0.0636
Loa Loa (eye worm) cytochrome P450 family protein 0.0041 0.0195 0.0298
Trichomonas vaginalis glucosylceramidase, putative 0.0289 0.2067 0.2776
Schistosoma mansoni hypothetical protein 0.0301 0.216 0.6453
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0375 0.2719 1
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0551
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0086 0.0532 0.2261
Plasmodium vivax DNA gyrase subunit A, putative 0.0066 0.0381 0.1138
Echinococcus multilocularis rhodopsin orphan GPCR 0.0063 0.036 0.0471
Trichomonas vaginalis mismatch repair protein Mlh1C (mutL homolog) 0.0016 0.0004 0.0005
Echinococcus multilocularis g protein coupled receptor 0.0063 0.036 0.0471
Toxoplasma gondii cytochrome p450 superfamily protein 0.0032 0.0122 0.0364
Trichomonas vaginalis inositol monophosphatase, putative 0.0086 0.0532 0.0714
Loa Loa (eye worm) hypothetical protein 0.0016 0.0005 0.0008
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0099 0.0636 0.0833
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.0099 0.0636 0.2328
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0061 0.0344 0.0344
Onchocerca volvulus 0.0043 0.0206 0.0276
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0063 0.036 0.0471
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0016 0.0006 0.0018
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0127 0.0848 0.1298
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0027 0.0091 0.014
Onchocerca volvulus 0.003 0.0111 0.0148
Echinococcus granulosus orexin receptor type 2 0.0063 0.036 0.0471
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0018 0.0019 0.0056
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0056 0.0306 0.0306
Echinococcus multilocularis neuropeptide Y receptor 0.0063 0.036 0.0471
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0021 0.0039 0.0117
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0099 0.0636 0.0833
Leishmania major hypothetical protein, conserved 0.0016 0.0004 0.0004
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0126 0.0837 0.2499
Leishmania major mitochondrial DNA topoisomerase II 0.0247 0.1755 0.1755
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0275 0.1966 0.3012
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0056 0.0306 0.0306
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0018 0.0019 0.0056
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0458 0.3348 1
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0099 0.0636 0.19
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0551
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0551
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0099 0.0636 0.0636
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0018 0.0019 0.0024
Chlamydia trachomatis thioredoxin reductase 0.0099 0.0636 0.2328
Echinococcus granulosus peptide allatostatin:somatostatin 0.0063 0.036 0.0471
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0027 0.0091 0.014
Schistosoma mansoni disulfide oxidoreductase 0.0099 0.0636 0.19
Giardia lamblia Thioredoxin reductase 0.0099 0.0636 0.2328
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0427 0.3117 0.4775
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0099 0.0636 0.189
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0126 0.0837 0.2499
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0016 0.0004 0.0012
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0056 0.0306 0.0469
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0375 0.2719 0.8119
Echinococcus multilocularis sodium and chloride dependent glycine 0.0018 0.0019 0.0024
Trichomonas vaginalis apoptosis inducing factor, putative 0.0099 0.0636 0.0854
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.003 0.0111 0.0319
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0126 0.0837 0.2499
Brugia malayi Melatonin receptor type 1A 0.0063 0.036 0.0551
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0099 0.0636 0.0636
Schistosoma mansoni sodium/chloride dependent transporter 0.0105 0.068 0.203
Brugia malayi Thioredoxin reductase 0.0458 0.3348 0.5128
Toxoplasma gondii NADPH-glutathione reductase 0.0375 0.2719 0.8121
Echinococcus granulosus biogenic amine 5HT receptor 0.0063 0.036 0.0471
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0027 0.0091 0.014
Echinococcus granulosus neuropeptide receptor 0.0063 0.036 0.0471
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0063 0.036 0.0483
Trypanosoma cruzi NADH dehydrogenase, putative 0.0099 0.0636 0.0636
Brugia malayi Importin beta-1 subunit 0.0028 0.0096 0.0147
Leishmania major heat shock protein 83-1 0.0016 0.0004 0.0004
Onchocerca volvulus 0.003 0.0111 0.0148
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0018 0.0019 0.0029
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0027 0.0091 0.012
Schistosoma mansoni hypothetical protein 0.004 0.0188 0.0563
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0016 0.0004 0.0012
Echinococcus multilocularis sodium and chloride dependent glycine 0.0018 0.0019 0.0024
Loa Loa (eye worm) hypothetical protein 0.0218 0.1536 0.2353
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0018 0.0019 0.0024
Treponema pallidum oxidoreductase 0.0099 0.0636 0.2328
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0551
Loa Loa (eye worm) hypothetical protein 0.0043 0.0206 0.0315
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0099 0.0636 0.2328
Echinococcus multilocularis caspase 8 0.0015 0.00000004697 0.000000061542
Schistosoma mansoni sodium/chloride dependent transporter 0.0018 0.0019 0.0056
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0099 0.0636 0.0854
Brugia malayi Cytochrome P450 family protein 0.0041 0.0195 0.0298
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0099 0.0636 0.189
Loa Loa (eye worm) hypothetical protein 0.0099 0.0636 0.0974
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0017 0.0015 0.0019
Loa Loa (eye worm) hypothetical protein 0.0027 0.0091 0.014
Trichomonas vaginalis endoplasmin, putative 0.0016 0.0004 0.0005
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0023 0.0056 0.0086
Loa Loa (eye worm) hypothetical protein 0.0126 0.0837 0.1281
Schistosoma mansoni hypothetical protein 0.0057 0.0313 0.0934
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0063 0.036 0.0471
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0086 0.0532 0.1943
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0056 0.0075
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0086 0.0532 0.0532
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0027 0.0091 0.014
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0063 0.036 0.1074
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0027 0.0091 0.012
Trypanosoma brucei heat shock protein 90, putative 0.0016 0.0004 0.0004
Trichomonas vaginalis mercuric reductase, putative 0.0375 0.2719 0.3651
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0063 0.036 0.0551
Trypanosoma cruzi hypothetical protein, conserved 0.0099 0.0636 0.0636
Leishmania major heat shock protein 83-1 0.0016 0.0004 0.0004
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0099 0.0636 0.0854
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0063 0.036 0.1074
Leishmania major heat shock protein 83-1 0.0016 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.003 0.0111 0.0169
Echinococcus granulosus neuropeptides capa receptor 0.0063 0.036 0.0471
Entamoeba histolytica hypothetical protein 0.0017 0.0015 0.0046
Trichomonas vaginalis glutathione reductase, putative 0.0375 0.2719 0.3651
Schistosoma mansoni biogenic amine receptor 0.0063 0.036 0.1074
Trichomonas vaginalis two component sensor and regulator histidine kinase bacteria, putative 0.0016 0.0004 0.0005
Trichomonas vaginalis glucosylceramidase, putative 0.0189 0.1316 0.1768
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0027 0.0091 0.012
Toxoplasma gondii Erv1 / Alr family protein 0.0061 0.0344 0.1029
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0032 0.0122 0.0353
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0018 0.0019 0.0024
Brugia malayi follicle stimulating hormone receptor 0.0063 0.036 0.0551
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1337 1 1
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0551
Brugia malayi Dopamine receptor 0.0063 0.036 0.0551
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0099 0.0636 0.0833
Brugia malayi nuclear receptor NHR-88 0.0027 0.0091 0.014
Schistosoma mansoni intermediate filament proteins 0.0043 0.0206 0.0615
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0041 0.019 0.0249
Toxoplasma gondii heat shock protein HSP90 0.0016 0.0004 0.0012
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0063 0.036 0.1074
Trichomonas vaginalis glucosylceramidase, putative 0.02 0.1393 0.1871
Schistosoma mansoni hypothetical protein 0.0032 0.0122 0.0364
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0375 0.2719 0.2719
Echinococcus multilocularis rhodopsin orphan GPCR 0.0063 0.036 0.0471
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0299 0.2149 0.3291
Echinococcus granulosus histone lysine methyltransferase setb 0.0126 0.0837 0.1096
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0032 0.0122 0.0435
Brugia malayi Uncoordinated protein 44 0.0016 0.0005 0.0008
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0082 0.0507 0.1503
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0032 0.0122 0.0353
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0099 0.0636 0.2328
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.004 0.0188 0.0247
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0225 0.1587 0.2131
Echinococcus multilocularis rhodopsin orphan GPCR 0.0063 0.036 0.0471
Schistosoma mansoni ran 0.0021 0.004 0.0118
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0126 0.0837 0.2499
Trichomonas vaginalis glucosylceramidase, putative 0.0289 0.2067 0.2776
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0029
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0099 0.0636 0.19
Brugia malayi Steroid receptor seven-up type 2 0.0027 0.0091 0.014
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0063 0.036 0.1074
Schistosoma mansoni amine GPCR 0.0063 0.036 0.1074
Echinococcus multilocularis g protein coupled receptor 0.0063 0.036 0.0471
Trypanosoma brucei trypanothione reductase 0.0458 0.3348 0.3348
Echinococcus granulosus intermediate filament protein 0.0043 0.0206 0.027
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0086 0.0532 0.1588
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0099 0.0636 0.189
Echinococcus granulosus rhodopsin orphan GPCR 0.0063 0.036 0.0471
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0099 0.0636 0.2328
Echinococcus granulosus neuropeptide s receptor 0.0577 0.4249 0.5568
Echinococcus multilocularis dro:myosuppressin receptor 0.0063 0.036 0.0471
Onchocerca volvulus 0.0063 0.036 0.0483
Brugia malayi G-protein coupled receptor 0.0063 0.036 0.0551
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0099 0.0636 0.0833
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0027 0.0091 0.014
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.002
Brugia malayi Death domain containing protein 0.0016 0.0005 0.0008
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0099 0.0636 0.2328
Leishmania major DNA topoisomerase ii 0.0324 0.2338 0.2338
Echinococcus granulosus g-protein coupled receptor 0.0063 0.036 0.0471
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0099 0.0636 0.0974
Leishmania major hypothetical protein, conserved 0.0099 0.0636 0.0636
Trypanosoma brucei heat shock protein, putative 0.0016 0.0004 0.0004
Echinococcus granulosus BC026374 protein S09 family 0.003 0.0111 0.0145
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0099 0.0636 0.0833
Echinococcus granulosus mitogen activated protein kinase 0.0056 0.0306 0.0401
Leishmania major hypothetical protein, conserved 0.0099 0.0636 0.0636
Leishmania major heat shock protein 83-1 0.0016 0.0004 0.0004
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0027 0.0091 0.014
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0099 0.0636 0.0636
Brugia malayi GnHR receptor homolog 0.0063 0.036 0.0551
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0247 0.1755 0.1755
Loa Loa (eye worm) G-protein coupled receptor 0.0063 0.036 0.0551
Echinococcus granulosus thioredoxin glutathione reductase 0.0458 0.3348 0.4387
Trypanosoma cruzi developmentally regulated phosphoprotein, putative 0.0016 0.0004 0.0004
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0375 0.2719 0.8121
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0032 0.0122 0.0435
Echinococcus granulosus inositol monophosphatase 1 0.0086 0.0532 0.0697
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0016 0.0005 0.0008
Brugia malayi Carboxylesterase family protein 0.003 0.0111 0.0169
Schistosoma mansoni neuropeptide receptor 0.0063 0.036 0.1074
Trichomonas vaginalis ran, putative 0.0021 0.004 0.0053
Trichomonas vaginalis glucosylceramidase, putative 0.0189 0.1316 0.1768
Schistosoma mansoni endoplasmin 0.0016 0.0004 0.0012
Schistosoma mansoni sulfide quinone reductase 0.0099 0.0636 0.19
Onchocerca volvulus 0.1 0.7447 1
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0126 0.0837 0.2499
Loa Loa (eye worm) hypothetical protein 0.0027 0.0091 0.014
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0551
Leishmania major heat shock protein 83-1 0.0016 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0021 0.0039 0.006
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0551
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0099 0.0636 0.0833
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0099 0.0636 0.2328
Plasmodium falciparum thioredoxin reductase 0.0458 0.3348 1
Echinococcus granulosus neuropeptide FF receptor 2 0.0063 0.036 0.0471
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0551
Brugia malayi Tachykinin-like peptides receptor 99D 0.0063 0.036 0.0551
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0027 0.0091 0.014
Leishmania major heat shock protein 83-1 0.0016 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.003 0.0111 0.0169
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.007 0.0412 0.054
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0032 0.0122 0.0353
Plasmodium vivax heat shock protein 86, putative 0.0016 0.0004 0.0012
Echinococcus granulosus tachykinin peptides receptor 99D 0.0063 0.036 0.0471
Loa Loa (eye worm) hypothetical protein 0.0178 0.1228 0.188
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0027 0.0091 0.0123
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0063 0.036 0.1074
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0105 0.068 0.1041
Schistosoma mansoni neuropeptide F-like receptor 0.0063 0.036 0.1074
Plasmodium vivax glutathione reductase, putative 0.0458 0.3348 1
Brugia malayi steroid hormone receptor 0.0027 0.0091 0.014
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0015 0.00000004697 0.0000001403
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0375 0.2719 0.8121
Onchocerca volvulus 0.0018 0.0019 0.0025
Brugia malayi hypothetical protein 0.0018 0.0019 0.0029
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0032 0.0122 0.0435
Toxoplasma gondii Erv1 / Alr family protein 0.0061 0.0344 0.1029
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0029
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0056 0.0306 0.0915
Loa Loa (eye worm) hypothetical protein 0.0272 0.1939 0.297
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0551
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0029
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0063 0.036 0.1074
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0063 0.036 0.1074
Echinococcus granulosus rhodopsin orphan GPCR 0.0063 0.036 0.0471
Loa Loa (eye worm) programmed cell death 8 0.0099 0.0636 0.0974
Plasmodium falciparum transporter, putative 0.0018 0.0019 0.0056
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0027 0.0091 0.0273
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0551
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0063 0.036 0.0471
Plasmodium falciparum DNA gyrase subunit A 0.0066 0.0381 0.1138
Plasmodium falciparum amino acid transporter, putative 0.0018 0.0019 0.0056
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0027 0.0091 0.0273
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0099 0.0636 0.19
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.003 0.0111 0.033
Schistosoma mansoni hypothetical protein 0.0063 0.036 0.1074
Echinococcus granulosus fmrfamide receptor 0.0063 0.036 0.0471
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1126 0.8398 0.8398
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0063 0.036 0.0471
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0375 0.2719 0.3562
Schistosoma mansoni neuropeptide receptor 0.0063 0.036 0.1074
Schistosoma mansoni hypothetical protein 0.0087 0.0542 0.162
Chlamydia trachomatis DNA gyrase subunit B 0.0082 0.0507 0.1852
Loa Loa (eye worm) TOPoisomerase family member 0.0324 0.2338 0.3581
Echinococcus multilocularis BC026374 protein (S09 family) 0.003 0.0111 0.0145
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0126 0.0837 0.1096
Loa Loa (eye worm) hypothetical protein 0.004 0.0188 0.0289
Brugia malayi hypothetical protein 0.0017 0.0015 0.0023
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0032 0.0122 0.0435
Echinococcus granulosus caspase 8 0.0015 0.00000004697 0.000000061542
Trypanosoma brucei cytochrome P450, putative 0.0041 0.0195 0.0195
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0032 0.0122 0.0353
Trichomonas vaginalis glucosylceramidase, putative 0.0189 0.1316 0.1768
Leishmania major GTP-binding protein, putative 0.0021 0.004 0.004
Trypanosoma brucei hypothetical protein, conserved 0.0099 0.0636 0.0636
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.004 0.0118
Echinococcus granulosus g protein coupled receptor 0.0063 0.036 0.0471
Schistosoma mansoni nuclear hormone receptor 0.0027 0.0091 0.0273
Brugia malayi hypothetical protein 0.0063 0.036 0.0551
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0016 0.0004 0.0005
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0099 0.0636 0.2328
Brugia malayi ecdysteroid receptor 0.0027 0.0091 0.014
Mycobacterium tuberculosis Probable reductase 0.0099 0.0636 0.189
Brugia malayi RNA, U transporter 1 0.008 0.0487 0.0746
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.004 0.0061
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0027 0.0091 0.014
Plasmodium vivax DNA topoisomerase II, putative 0.0324 0.2338 0.6982
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0063 0.036 0.0471
Schistosoma mansoni sodium/chloride dependent transporter 0.0018 0.0022 0.0067
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0099 0.0636 0.2328
Onchocerca volvulus 0.0063 0.036 0.0483
Onchocerca volvulus 0.0063 0.036 0.0483
Trypanosoma cruzi Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0016 0.0004 0.0004
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0056 0.0306 0.0306
Loa Loa (eye worm) hypothetical protein 0.0159 0.109 0.1669
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0018 0.0019 0.0056
Schistosoma mansoni glutamate synthase 0.0099 0.0636 0.19
Schistosoma mansoni neuropeptide receptor 0.0063 0.036 0.1074
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0027 0.0091 0.014
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0027 0.0091 0.012
Entamoeba histolytica acetyltransferase, GNAT family 0.0019 0.0026 0.0095
Schistosoma mansoni glutamate synthase 0.0099 0.0636 0.19
Onchocerca volvulus 0.003 0.0111 0.0148
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.004 0.0131
Schistosoma mansoni thyroid hormone receptor 0.0027 0.0091 0.0273
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0551
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0016 0.0005 0.0007
Echinococcus multilocularis rhodopsin orphan GPCR 0.0063 0.036 0.0471
Trypanosoma brucei DNA topoisomerase ii 0.0247 0.1755 0.1755
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.003 0.0111 0.033
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0032 0.0122 0.0435
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.004 0.0188 0.0247
Trypanosoma cruzi heat shock protein 90, putative 0.0016 0.0004 0.0004
Trypanosoma cruzi NADH dehydrogenase, putative 0.0099 0.0636 0.0636
Treponema pallidum sodium- and chloride- dependent transporter 0.0105 0.068 0.2489
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0032 0.0122 0.0435
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0099 0.0636 0.0974
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.004 0.004
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0016 0.0005 0.0007
Leishmania major cytochrome p450-like protein 0.0041 0.0195 0.0195
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0063 0.036 0.1074
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0984 0.7326 0.7326
Brugia malayi acetyltransferase, GNAT family protein 0.007 0.0412 0.0632
Echinococcus granulosus neuropeptide Y receptor 0.0063 0.036 0.0471
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0652 0.4813 0.6306
Loa Loa (eye worm) MH2 domain-containing protein 0.0093 0.0588 0.0901
Loa Loa (eye worm) serotonin transporter b 0.0105 0.068 0.1041
Echinococcus granulosus somatostatin receptor 0.0063 0.036 0.0471
Trichomonas vaginalis heat shock protein, putative 0.0016 0.0004 0.0005
Brugia malayi Carboxylesterase family protein 0.003 0.0111 0.0169
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0086 0.0532 0.0532
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0105 0.068 0.203
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0063 0.036 0.0471
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0032 0.0122 0.0122
Plasmodium falciparum ferrodoxin reductase-like protein 0.0099 0.0636 0.19
Echinococcus multilocularis neuropeptide s receptor 0.0577 0.4249 0.5568
Schistosoma mansoni hypothetical protein 0.0033 0.0133 0.0396
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0032 0.0122 0.0353
Plasmodium vivax endoplasmin, putative 0.0016 0.0004 0.0012
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0018 0.0019 0.0024
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0272 0.1939 0.297
Mycobacterium ulcerans DNA gyrase subunit B 0.0082 0.0507 0.1852
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0099 0.0636 0.0636
Echinococcus multilocularis fmrfamide receptor 0.0063 0.036 0.0471
Echinococcus multilocularis para nitrobenzyl esterase 0.003 0.0111 0.0145
Entamoeba histolytica DNA topoisomerase II, putative 0.0324 0.2338 1
Schistosoma mansoni myosin xvIII 0.0063 0.036 0.1074
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0056 0.0306 0.0306
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0032 0.0122 0.0353
Onchocerca volvulus 0.003 0.0111 0.0148
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0027 0.0091 0.014
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0032 0.0122 0.0435
Schistosoma mansoni hypothetical protein 0.004 0.0188 0.0563
Echinococcus granulosus contactin 0.0017 0.0013 0.0017
Trypanosoma cruzi heat shock protein 85, putative 0.0016 0.0004 0.0004
Schistosoma mansoni coup transcription factor 0.0027 0.0091 0.0273
Echinococcus granulosus death domain containing protein 0.0016 0.0005 0.0007
Trypanosoma brucei heat shock protein, putative 0.0016 0.0004 0.0004
Plasmodium falciparum glutathione reductase 0.0375 0.2719 0.8121
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0018 0.0019 0.0029
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0018 0.0019 0.0056
Schistosoma mansoni sulfide quinone reductase 0.0099 0.0636 0.19
Schistosoma mansoni hypothetical protein 0.0017 0.0015 0.0044
Echinococcus multilocularis musashi 0.0043 0.0206 0.027
Leishmania major NADH dehydrogenase, putative 0.0099 0.0636 0.0636
Echinococcus granulosus nuclear factor of activated T cells 5 0.0082 0.0506 0.0663
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0082 0.0507 0.1852
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.1126 0.8398 0.8398
Schistosoma mansoni steroid hormone receptor ad4bp 0.0027 0.0091 0.0273
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0061 0.0344 0.0451
Brugia malayi Carboxylesterase family protein 0.0178 0.1228 0.188
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0551
Onchocerca volvulus 0.0105 0.068 0.0913
Loa Loa (eye worm) CYP4Cod1 0.0041 0.0195 0.0298
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0551
Echinococcus multilocularis neuropeptide receptor A26 0.0577 0.4249 0.5568
Plasmodium vivax hypothetical protein, conserved 0.0016 0.0004 0.0012
Loa Loa (eye worm) G-protein coupled receptor 0.0063 0.036 0.0551
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0018 0.0019 0.0056
Echinococcus granulosus neuropeptide Y receptor 0.0063 0.036 0.0471
Onchocerca volvulus 0.0063 0.036 0.0483
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0018 0.0019 0.0024
Loa Loa (eye worm) hypothetical protein 0.0105 0.068 0.1041
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0099 0.0636 0.0636
Echinococcus multilocularis GPCR, family 2 0.004 0.0188 0.0247
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0018 0.0019 0.0024
Mycobacterium ulcerans dehydrogenase 0.0099 0.0636 0.2328
Echinococcus granulosus snurportin 1 0.0299 0.2149 0.2815
Echinococcus multilocularis lamin 0.0043 0.0206 0.027
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0099 0.0636 0.0636
Leishmania major heat shock protein 83-1 0.0016 0.0004 0.0004
Brugia malayi Nuclear hormone receptor-like 1 0.0027 0.0091 0.014
Schistosoma mansoni inositol monophosphatase 0.0086 0.0532 0.1588
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0032 0.0122 0.0435
Onchocerca volvulus 0.003 0.0111 0.0148
Trichomonas vaginalis receptor histidine kinase, putative 0.0016 0.0004 0.0005
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0063 0.036 0.1074
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0099 0.0636 0.189
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0099 0.0636 0.0833
Brugia malayi Latrophilin receptor protein 2 0.004 0.0188 0.0289
Treponema pallidum DNA gyrase, subunit A (gyrA) 0.0066 0.0381 0.1389
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0027 0.0091 0.014
Echinococcus multilocularis allatostatin A receptor 0.0063 0.036 0.0471
Trichomonas vaginalis glucosylceramidase, putative 0.0289 0.2067 0.2776
Onchocerca volvulus Protein ultraspiracle homolog 0.0027 0.0091 0.0123
Brugia malayi ORL1-like opioid receptor 0.0063 0.036 0.0551
Entamoeba histolytica thioredoxin reductase, putative 0.0099 0.0636 0.2708
Trypanosoma brucei heat shock protein, putative 0.0016 0.0004 0.0004
Leishmania major heat shock protein 83-1 0.0016 0.0004 0.0004
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0099 0.0636 0.0833
Brugia malayi AKH receptor 0.0063 0.036 0.0551
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0375 0.2719 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0063 0.036 0.0471
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0027 0.0091 0.014
Loa Loa (eye worm) neuropeptide F receptor 0.0063 0.036 0.0551
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0027 0.0091 0.012
Echinococcus multilocularis acetylcholinesterase 0.0178 0.1228 0.1609
Trichomonas vaginalis receptor histidine kinase, putative 0.0016 0.0004 0.0005
Schistosoma mansoni amine GPCR 0.0447 0.3269 0.9763
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0018 0.0019 0.0056
Echinococcus multilocularis heat shock protein 90 0.0016 0.0004 0.0005
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0027 0.0091 0.014
Schistosoma mansoni opsin-like receptor 0.0063 0.036 0.1074
Loa Loa (eye worm) steroid hormone receptor 0.0027 0.0091 0.014
Schistosoma mansoni amine GPCR 0.0063 0.036 0.1074
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0063 0.036 0.1074
Echinococcus granulosus carboxylesterase 5A 0.0178 0.1228 0.1609
Echinococcus multilocularis carboxylesterase 5A 0.0178 0.1228 0.1609
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0063 0.036 0.0471
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0016 0.0004 0.0005
Loa Loa (eye worm) thioredoxin reductase 0.0458 0.3348 0.5128
Echinococcus multilocularis neuroligin 0.003 0.0111 0.0145
Trypanosoma cruzi cytochrome P450, putative 0.0041 0.0195 0.0195
Echinococcus multilocularis acetylcholinesterase 0.0178 0.1228 0.1609
Echinococcus granulosus tm gpcr rhodopsin 0.0063 0.036 0.0471
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.1024 0.7632 1
Schistosoma mansoni neuroligin 3 (S09 family) 0.003 0.0111 0.033
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0551
Echinococcus granulosus geminin 0.0301 0.216 0.2831
Wolbachia endosymbiont of Brugia malayi DNA gyrase subunit A 0.0066 0.0381 0.1389
Loa Loa (eye worm) hypothetical protein 0.0039 0.0182 0.0278
Plasmodium falciparum DNA gyrase subunit B 0.0082 0.0507 0.1513
Plasmodium falciparum DNA topoisomerase VI, b subunit, putative 0.0016 0.0004 0.0012
Toxoplasma gondii thioredoxin reductase 0.0458 0.3348 1
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0063 0.036 0.1074
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0375 0.2719 0.8121
Schistosoma mansoni DNA topoisomerase II 0.0324 0.2338 0.6982
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0041 0.0195 0.0702
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0127 0.0848 0.1298
Loa Loa (eye worm) carboxylesterase 0.003 0.0111 0.0169
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0063 0.036 0.0471
Schistosoma mansoni hypothetical protein 0.0099 0.0636 0.19
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0032 0.0122 0.0353
Onchocerca volvulus 0.0063 0.036 0.0483
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0018 0.0019 0.0029
Loa Loa (eye worm) glutathione reductase 0.0458 0.3348 0.5128
Loa Loa (eye worm) acetylcholinesterase 1 0.0178 0.1228 0.188
Echinococcus granulosus acetylcholinesterase 0.0178 0.1228 0.1609
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0099 0.0636 0.0636
Mycobacterium leprae putative cytochrome p450 0.0032 0.0122 0.0435
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0099 0.0636 0.189
Trichomonas vaginalis glutamate synthase, putative 0.0099 0.0636 0.0854
Plasmodium vivax thioredoxin reductase, putative 0.0458 0.3348 1
Mycobacterium ulcerans NADH dehydrogenase 0.0099 0.0636 0.2328
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0375 0.2719 1
Trichomonas vaginalis glucosylceramidase, putative 0.0289 0.2067 0.2776
Loa Loa (eye worm) hypothetical protein 0.0544 0.3996 0.6121
Echinococcus granulosus ecdysone induced protein 78C 0.0027 0.0091 0.012
Echinococcus granulosus alpha 1A adrenergic receptor 0.0063 0.036 0.0471
Brugia malayi hypothetical protein 0.0017 0.0013 0.002
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.004 0.0052
Schistosoma mansoni acetylcholinesterase 0.003 0.0111 0.033
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0099 0.0636 0.0636
Echinococcus multilocularis mitogen activated protein kinase 3 0.0056 0.0306 0.0401
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0032 0.0122 0.0353
Trypanosoma brucei heat shock protein, putative 0.0016 0.0004 0.0004
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0375 0.2719 0.8121
Brugia malayi Intermediate filament tail domain containing protein 0.0043 0.0206 0.0315
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0032 0.0122 0.0435
Trichomonas vaginalis glucosylceramidase, putative 0.0189 0.1316 0.1768
Trichomonas vaginalis CMGC family protein kinase 0.0056 0.0306 0.0411
Echinococcus multilocularis g protein coupled receptor 0.0063 0.036 0.0471
Echinococcus granulosus glutamate synthase 0.0099 0.0636 0.0833
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.004 0.0188 0.0247
Trichomonas vaginalis CMGC family protein kinase 0.0056 0.0306 0.0411
Schistosoma mansoni biogenic amine (5HT) receptor 0.0063 0.036 0.1074
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.004 0.0061
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0063 0.036 0.0471
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0375 0.2719 0.2719
Brugia malayi heat shock protein 90 0.0016 0.0004 0.0006
Trichomonas vaginalis DNA topoisomerase II, putative 0.0324 0.2338 0.3139
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0032 0.0122 0.0435
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0551
Brugia malayi photoreceptor-specific nuclear receptor 0.0027 0.0091 0.014
Trypanosoma brucei Heat shock protein 83, putative 0.0016 0.0004 0.0004
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0032 0.0122 0.0353
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0027 0.0091 0.012
Schistosoma mansoni BC026374 protein (S09 family) 0.003 0.0111 0.033
Echinococcus granulosus tm gpcr rhodopsin 0.0063 0.036 0.0471
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0427 0.3117 0.3117
Trichomonas vaginalis CMGC family protein kinase 0.0056 0.0306 0.0411
Schistosoma mansoni hypothetical protein 0.004 0.0188 0.0563
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0099 0.0636 0.2708
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0063 0.036 0.0551
Schistosoma mansoni hypothetical protein 0.0063 0.036 0.1074
Schistosoma mansoni hypothetical protein 0.0299 0.2149 0.6418
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0551
Echinococcus granulosus sodium and chloride dependent glycine 0.0018 0.0019 0.0024
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0027 0.0091 0.014
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0178 0.1228 0.3667
Echinococcus granulosus lamin dm0 0.0043 0.0206 0.027
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0099 0.0636 0.0854
Loa Loa (eye worm) hypothetical protein 0.0027 0.0091 0.014
Onchocerca volvulus Bile acid receptor homolog 0.0027 0.0091 0.0123
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0018 0.0019 0.0054
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0375 0.2719 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0111 0.0169
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0063 0.036 0.1074
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0063 0.036 0.1074
Echinococcus multilocularis netrin receptor unc 5 0.002 0.0038 0.005
Onchocerca volvulus 0.0063 0.036 0.0483
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0082 0.0506 0.0663
Trypanosoma cruzi heat shock protein 85, putative 0.0016 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0551
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0056 0.0056
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0041 0.019 0.0249
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0016 0.0004 0.0005
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0032 0.0122 0.0435
Echinococcus granulosus g protein coupled receptor 0.0063 0.036 0.0471
Onchocerca volvulus 0.0063 0.036 0.0483
Brugia malayi cytoplasmic intermediate filament protein 0.0023 0.0056 0.0086
Trichomonas vaginalis glucosylceramidase, putative 0.0189 0.1316 0.1768
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0017 0.0015 0.0019
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0032 0.0122 0.0435
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0289 0.2067 0.3166
Loa Loa (eye worm) carboxylesterase 0.003 0.0111 0.0169
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0018 0.0019 0.0056
Onchocerca volvulus 0.0099 0.0636 0.0854
Brugia malayi bZIP transcription factor family protein 0.0041 0.019 0.0291
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0056 0.0075
Schistosoma mansoni endoplasmin 0.0016 0.0004 0.0012
Onchocerca volvulus 0.0063 0.036 0.0483
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0551
Brugia malayi latrophilin 2 splice variant baaae 0.0087 0.0542 0.0831
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0086 0.0532 0.1943
Loa Loa (eye worm) cytochrome P450 family protein 0.0032 0.0122 0.0187
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0375 0.2719 0.8119
Schistosoma mansoni pyruvate dehydrogenase 0.0016 0.0004 0.0012
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0225 0.1587 0.2131
Chlamydia trachomatis DNA gyrase subunit B 0.0159 0.109 0.3999
Plasmodium vivax hypothetical protein, conserved 0.0018 0.0019 0.0056
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0032 0.0122 0.0353
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0375 0.2719 1
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.003 0.0111 0.0145
Schistosoma mansoni inositol monophosphatase 0.0086 0.0532 0.1588
Brugia malayi G-protein coupled receptor 0.0063 0.036 0.0551
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0099 0.0636 0.0833
Leishmania major heat shock protein 83-1 0.0016 0.0004 0.0004
Loa Loa (eye worm) melatonin receptor type 1A 0.0063 0.036 0.0551
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0063 0.036 0.1074
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.003 0.0111 0.0319
Trypanosoma brucei C-8 sterol isomerase, putative 0.0427 0.3117 0.3117
Mycobacterium ulcerans glutamate synthase subunit beta 0.0099 0.0636 0.2328
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0032 0.0122 0.0435
Echinococcus granulosus Ankyrin 0.0016 0.0006 0.0008
Echinococcus granulosus rhodopsin orphan GPCR 0.0063 0.036 0.0471
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0099 0.0636 0.189
Brugia malayi Serotonin receptor 0.0597 0.44 0.674
Loa Loa (eye worm) hypothetical protein 0.0105 0.068 0.1041
Loa Loa (eye worm) hypothetical protein 0.003 0.0111 0.0169
Plasmodium falciparum DNA topoisomerase 2 0.0324 0.2338 0.6982
Schistosoma mansoni growth hormone secretagogue receptor 0.0063 0.036 0.1074
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0063 0.036 0.0551
Chlamydia trachomatis DNA gyrase subunit A 0.0066 0.0381 0.1389
Brugia malayi larval opioid receptor 0.0063 0.036 0.0551
Echinococcus multilocularis thyroid hormone receptor alpha 0.0027 0.0091 0.012
Brugia malayi kinase, mitochondrial precursor 0.0016 0.0004 0.0006
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0027 0.0091 0.014
Echinococcus granulosus hypothetical protein 0.0864 0.642 0.8412
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0018 0.0019 0.0029
Trypanosoma cruzi hypothetical protein, conserved 0.0099 0.0636 0.0636
Brugia malayi glutathione reductase 0.0458 0.3348 0.5128
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0032 0.0122 0.0435
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0032 0.0122 0.0353
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.004 0.004
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0056 0.0306 0.0306
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0032 0.0122 0.0353
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0324 0.2338 0.3063
Brugia malayi nuclear hormone receptor 0.0027 0.0091 0.014
Plasmodium falciparum glutathione reductase 0.0458 0.3348 1
Echinococcus multilocularis neuropeptides capa receptor 0.0063 0.036 0.0471
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0099 0.0636 0.189
Echinococcus granulosus hemicentin 1 0.0017 0.0013 0.0017
Schistosoma mansoni hypothetical protein 0.004 0.0188 0.0563
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0551
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0018 0.0019 0.0029
Echinococcus granulosus biogenic amine 5HT receptor 0.0063 0.036 0.0471
Leishmania major hypothetical protein, conserved 0.0099 0.0636 0.0636
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0018 0.0019 0.0056
Schistosoma mansoni lamin 0.0043 0.0206 0.0615
Plasmodium vivax ferrodoxin reductase, putative 0.0099 0.0636 0.19
Echinococcus multilocularis thioredoxin glutathione reductase 0.0458 0.3348 0.4387
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0551
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0086 0.0532 0.0714
Loa Loa (eye worm) neuropeptide F receptor 0.0063 0.036 0.0551
Leishmania major hypothetical protein, conserved 0.0061 0.0344 0.0344
Echinococcus multilocularis hemicentin 1 0.0017 0.0013 0.0017
Schistosoma mansoni hypothetical protein 0.0016 0.0005 0.0015
Echinococcus multilocularis fmrfamide receptor 0.0063 0.036 0.0471
Echinococcus granulosus para nitrobenzyl esterase 0.003 0.0111 0.0145
Leishmania major trypanothione reductase 0.0458 0.3348 0.3348
Echinococcus granulosus jun protein 0.0041 0.019 0.0249
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0324 0.2338 0.3063
Leishmania major importin beta-1 subunit, putative 0.0023 0.0056 0.0056
Entamoeba histolytica hypothetical protein 0.0017 0.0015 0.0046
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.004 0.0052
Schistosoma mansoni histamine h1 receptor 0.0063 0.036 0.1074
Echinococcus multilocularis conserved hypothetical protein 0.0801 0.5944 0.7788
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0551
Echinococcus multilocularis g-protein coupled receptor 0.0063 0.036 0.0471
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0056 0.0075
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0039 0.0052
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0289 0.2067 0.3166
Leishmania major heat shock protein 83-1 0.0016 0.0004 0.0004
Schistosoma mansoni glutamate synthase 0.0099 0.0636 0.19
Treponema pallidum NADH oxidase 0.0375 0.2719 1
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0099 0.0636 0.19
Schistosoma mansoni serine/threonine protein kinase 0.0056 0.0306 0.0915
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0551
Echinococcus multilocularis neuropeptide receptor 0.0063 0.036 0.0471
Loa Loa (eye worm) hypothetical protein 0.0427 0.3117 0.4775
Schistosoma mansoni opsin-like receptor 0.0063 0.036 0.1074
Schistosoma mansoni jun-related protein 0.0033 0.0133 0.0396
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0375 0.2719 0.3562
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0027 0.0091 0.012
Echinococcus multilocularis orexin receptor type 2 0.0063 0.036 0.0471
Brugia malayi RE15519p 0.0063 0.036 0.0551
Echinococcus granulosus lamin 0.0043 0.0206 0.027
Plasmodium falciparum thioredoxin reductase 0.0375 0.2719 0.8121
Echinococcus granulosus histone acetyltransferase KAT2B 0.0068 0.0398 0.0521
Brugia malayi Endoplasmin precursor 0.0016 0.0004 0.0006
Brugia malayi hypothetical protein 0.0063 0.036 0.0551
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0032 0.0122 0.0435
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.0016 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.0027 0.0091 0.014
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.004 0.0118
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0063 0.036 0.1074
Loa Loa (eye worm) hypothetical protein 0.0087 0.0542 0.0831
Schistosoma mansoni biogenic amine receptor 0.0063 0.036 0.1074
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.007 0.0412 0.1232
Plasmodium falciparum endoplasmin, putative 0.0016 0.0004 0.0012
Brugia malayi Pre-SET motif family protein 0.0878 0.6528 1
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0551
Loa Loa (eye worm) hypothetical protein 0.0077 0.0466 0.0715
Onchocerca volvulus 0.0043 0.0206 0.0276
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.004 0.004
Echinococcus granulosus rhodopsin orphan GPCR 0.0063 0.036 0.0471
Loa Loa (eye worm) endoplasmin 0.0016 0.0004 0.0006
Brugia malayi Carboxylesterase family protein 0.003 0.0111 0.0169
Trichomonas vaginalis sensor histidine kinase, putative 0.0016 0.0004 0.0005
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0032 0.0122 0.0353
Brugia malayi Immunoglobulin I-set domain containing protein 0.002 0.0038 0.0059
Mycobacterium tuberculosis Carboxylesterase LipT 0.003 0.0111 0.0319
Leishmania major developmentally regulated phosphoprotein-like protein 0.0016 0.0004 0.0004
Echinococcus granulosus 7tm_1 domain containing protein 0.0063 0.036 0.0471
Treponema pallidum thioredoxin reductase (trxB) 0.0099 0.0636 0.2328
Toxoplasma gondii hypothetical protein 0.0018 0.0019 0.0056
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0018 0.0019 0.0056
Schistosoma mansoni sodium-dependent amino acid transporter 0.0018 0.0019 0.0056
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0099 0.0636 0.2328
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0056 0.0306 0.0306
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.004 0.0188 0.0247
Plasmodium falciparum histone acetyltransferase GCN5 0.0019 0.0026 0.0078
Echinococcus multilocularis rhodopsin orphan GPCR 0.0063 0.036 0.0471
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0551
Leishmania major heat shock protein 83-1 0.0016 0.0004 0.0004
Schistosoma mansoni retinoic acid receptor RXR 0.0027 0.0091 0.0273
Onchocerca volvulus 0.0063 0.036 0.0483
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0099 0.0636 0.0833
Onchocerca volvulus 0.0063 0.036 0.0483
Brugia malayi Inositol-1 0.0086 0.0532 0.0814
Echinococcus multilocularis 0.0032 0.0122 0.016
Plasmodium falciparum heat shock protein 90 0.0016 0.0004 0.0012
Schistosoma mansoni gliotactin 0.003 0.0111 0.033
Brugia malayi hypothetical protein 0.0063 0.036 0.0551
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0096 0.0286
Onchocerca volvulus 0.0063 0.036 0.0483
Echinococcus granulosus rhodopsin orphan GPCR 0.0063 0.036 0.0471
Echinococcus multilocularis ecdysone induced protein 78C 0.0027 0.0091 0.012
Schistosoma mansoni heat shock protein 0.0016 0.0004 0.0012
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0984 0.7326 0.7326
Echinococcus granulosus neuroligin 0.003 0.0111 0.0145
Loa Loa (eye worm) hypothetical protein 0.0077 0.0466 0.0715
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0275 0.1966 0.3012
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0077 0.0464 0.1693
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0551
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0032 0.0122 0.0122
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0099 0.0636 0.2708
Echinococcus multilocularis somatostatin receptor 0.0063 0.036 0.0471
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0018 0.0019 0.0029
Loa Loa (eye worm) acetyltransferase 0.007 0.0412 0.0632
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0027 0.0091 0.012
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0027 0.0091 0.012
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0032 0.0122 0.0435
Brugia malayi Cytochrome P450 family protein 0.0032 0.0122 0.0187
Echinococcus multilocularis rhodopsin orphan GPCR 0.0063 0.036 0.0471
Mycobacterium ulcerans ferredoxin reductase 0.0099 0.0636 0.2328
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.003 0.0111 0.0148
Schistosoma mansoni neuropeptide receptor 0.0063 0.036 0.1074
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0032 0.0122 0.0353
Echinococcus granulosus neuropeptide receptor A26 0.0577 0.4249 0.5568
Loa Loa (eye worm) hypothetical protein 0.0242 0.1714 0.2626
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0099 0.0636 0.189
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0043 0.0206 0.0315
Brugia malayi intermediate filament protein 0.0043 0.0206 0.0315
Trichomonas vaginalis glucosylceramidase, putative 0.02 0.1393 0.1871
Brugia malayi Cytochrome P450 family protein 0.0032 0.0122 0.0187
Brugia malayi neuropeptide F receptor 0.0063 0.036 0.0551
Echinococcus multilocularis sex peptide receptor 0.0063 0.036 0.0471
Giardia lamblia Histone acetyltransferase GCN5 0.0019 0.0026 0.0081
Echinococcus multilocularis neuropeptide Y receptor 0.0063 0.036 0.0471
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0032 0.0122 0.0353
Brugia malayi Pre-SET motif family protein 0.0126 0.0837 0.1281
Schistosoma mansoni amine GPCR 0.0063 0.036 0.1074
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0032 0.0122 0.0435
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0086 0.0532 0.0532
Trichomonas vaginalis spcc417.12 protein, putative 0.003 0.0111 0.0148
Chlamydia trachomatis DNA gyrase subunit A 0.0066 0.0381 0.1389
Loa Loa (eye worm) hypothetical protein 0.0027 0.0091 0.014
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0086 0.0532 0.0714
Onchocerca volvulus 0.0018 0.0019 0.0025
Loa Loa (eye worm) cytochrome P450 0.0032 0.0122 0.0187
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0063 0.036 0.1074
Schistosoma mansoni adenoreceptor 0.0063 0.036 0.1074
Onchocerca volvulus 0.0063 0.036 0.0483
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0099 0.0636 0.2328
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0551
Trichomonas vaginalis heat shock protein, putative 0.0016 0.0004 0.0005
Brugia malayi hypothetical protein 0.0063 0.036 0.0551
Mycobacterium tuberculosis DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0066 0.0381 0.1128
Echinococcus granulosus neuropeptide receptor 0.0063 0.036 0.0471
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0551
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0551
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0099 0.0636 0.0833
Schistosoma mansoni neuropeptide f receptor 76f 0.0063 0.036 0.1074
Brugia malayi putative neuropeptide receptor 0.0063 0.036 0.0551
Schistosoma mansoni hypothetical protein 0.0301 0.216 0.6453
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0032 0.0122 0.0353
Trichomonas vaginalis sensory transduction histidine kinase, putative 0.0016 0.0004 0.0005
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0126 0.0837 0.1096
Echinococcus granulosus dro:myosuppressin receptor 0.0063 0.036 0.0471
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1337 1 1
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0099 0.0636 0.0854
Echinococcus granulosus serotonin transporter 0.0105 0.068 0.0891
Leishmania major heat shock protein 83-1 0.0016 0.0004 0.0004
Plasmodium vivax importin-beta 2, putative 0.0028 0.0096 0.0286
Entamoeba histolytica hypothetical protein 0.0017 0.0015 0.0046
Echinococcus granulosus 7TM GPCR rhodopsin 0.0063 0.036 0.0471
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0096 0.0125
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0099 0.0636 0.0833
Echinococcus granulosus mitogen activated protein kinase 3 0.0056 0.0306 0.0401
Mycobacterium ulcerans monoxygenase 0.0099 0.0636 0.2328
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0551
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.1337 1 1
Trypanosoma brucei Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0016 0.0004 0.0004
Echinococcus multilocularis snurportin 1 0.0299 0.2149 0.2815
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0027 0.0091 0.014
Onchocerca volvulus 0.0032 0.0124 0.0167
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0551
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0099 0.0636 0.189
Loa Loa (eye worm) hypothetical protein 0.0127 0.0848 0.1298
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0027 0.0091 0.0273
Echinococcus multilocularis inositol monophosphatase 1 0.0086 0.0532 0.0697
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0099 0.0636 0.0854
Loa Loa (eye worm) inositol-1 0.0086 0.0532 0.0814
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0032 0.0122 0.0353
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0099 0.0636 0.0854
Schistosoma mansoni netrin receptor unc5 0.002 0.0038 0.0114
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0027 0.0091 0.014
Leishmania major heat shock protein 83-1 0.0016 0.0004 0.0004
Leishmania major heat shock protein 83-1 0.0016 0.0004 0.0004
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0027 0.0091 0.012
Loa Loa (eye worm) hypothetical protein 0.0242 0.1714 0.2626
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0099 0.0636 0.2708
Trichomonas vaginalis glucosylceramidase, putative 0.0189 0.1316 0.1768
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0551
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0225 0.1587 0.2131
Entamoeba histolytica Ran family GTPase 0.0021 0.004 0.0153
Onchocerca volvulus 0.0063 0.036 0.0483
Brugia malayi hypothetical protein 0.0032 0.0124 0.019
Loa Loa (eye worm) cytochrome P450 family protein 0.0041 0.0195 0.0298
Trypanosoma cruzi heat shock protein 90, putative 0.0016 0.0004 0.0004
Trypanosoma cruzi heat shock protein 85, putative 0.0016 0.0004 0.0004
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0099 0.0636 0.0974
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0099 0.0636 0.19
Schistosoma mansoni titin 0.0017 0.0013 0.0039
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0099 0.0636 0.0636
Brugia malayi sulfakinin receptor protein 0.0063 0.036 0.0551
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0063 0.036 0.0471
Loa Loa (eye worm) hypothetical protein 0.0016 0.0004 0.0006
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0375 0.2719 1
Echinococcus multilocularis neuropeptide FF receptor 2 0.0063 0.036 0.0471
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.1126 0.8398 0.8398
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0551
Echinococcus granulosus sodium and chloride dependent glycine 0.0018 0.0019 0.0024
Loa Loa (eye worm) hypothetical protein 0.0027 0.0091 0.014
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0063 0.036 0.0551
Onchocerca volvulus 0.0027 0.0091 0.0123
Onchocerca volvulus 0.0063 0.036 0.0483
Echinococcus granulosus histone acetyltransferase KAT2B 0.0021 0.0039 0.0051
Giardia lamblia Glutamate synthase 0.0099 0.0636 0.2328
Loa Loa (eye worm) solute carrier family 6 member 4 0.0105 0.068 0.1041
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0063 0.036 0.1074
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0063 0.036 0.0551
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0063 0.036 0.0471
Trypanosoma brucei heat shock protein 90, putative 0.0016 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0027 0.0091 0.014
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0063 0.036 0.0551
Brugia malayi hypothetical protein 0.0063 0.036 0.0551
Brugia malayi Serotonin receptor 0.0063 0.036 0.0551
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0061 0.0344 0.1029
Loa Loa (eye worm) hypothetical protein 0.0105 0.068 0.1041
Trypanosoma brucei developmentally regulated phosphoprotein 0.0016 0.0004 0.0004
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0021 0.0039 0.0051
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0032 0.0122 0.0122
Echinococcus granulosus family S9 non peptidase ue S09 family 0.003 0.0111 0.0145
Echinococcus granulosus cytochrome P450 2K1 0.0032 0.0122 0.016
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0099 0.0636 0.2708
Loa Loa (eye worm) latrophilin receptor protein 2 0.004 0.0188 0.0289
Giardia lamblia Kinase, CMGC MAPK 0.0056 0.0306 0.1114
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0099 0.0636 0.2328
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0063 0.036 0.0471
Schistosoma mansoni ankyrin 23/unc44 0.0016 0.0005 0.0015
Brugia malayi cytochrome P450 0.0032 0.0122 0.0187
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0063 0.036 0.0471
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0017 0.0013 0.0039
Loa Loa (eye worm) hypothetical protein 0.003 0.0111 0.0169
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0375 0.2719 0.8121
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0099 0.0636 0.2708
Brugia malayi hypothetical protein 0.003 0.0111 0.0169
Echinococcus granulosus g protein coupled receptor 0.0063 0.036 0.0471
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0551
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0099 0.0636 0.19
Loa Loa (eye worm) norepinephrine transporter 0.0105 0.068 0.1041
Trichomonas vaginalis CMGC family protein kinase 0.0056 0.0306 0.0411
Leishmania major C-8 sterol isomerase-like protein 0.0427 0.3117 0.3117
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0878 0.6528 1
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0375 0.2719 0.2719
Echinococcus multilocularis neuropeptide receptor 0.0063 0.036 0.0471
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0099 0.0636 0.2328
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0027 0.0091 0.0273
Brugia malayi Dopamine receptor protein 1 0.0063 0.036 0.0551
Schistosoma mansoni amine GPCR 0.0063 0.036 0.1074
Trypanosoma brucei heat shock protein, putative 0.0016 0.0004 0.0004
Trypanosoma cruzi cytochrome P450, putative 0.0041 0.0195 0.0195
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0121 0.0801 0.105
Leishmania major heat shock protein 83-1 0.0016 0.0004 0.0004
Echinococcus granulosus GPCR family 2 0.004 0.0188 0.0247
Loa Loa (eye worm) transcription factor SMAD2 0.0093 0.0588 0.0901
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0324 0.2338 0.3581
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0032 0.0122 0.0122
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0061 0.0344 0.0344
Loa Loa (eye worm) hepatopoietin HPO2 0.0061 0.0344 0.0528
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0018 0.0019 0.0056
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0099 0.0636 0.0854
Loa Loa (eye worm) TYRA-2 protein 0.0063 0.036 0.0551
Echinococcus granulosus serotonin receptor 0.0063 0.036 0.0471
Brugia malayi Calcitonin receptor-like protein seb-1 0.0127 0.0848 0.1298
Schistosoma mansoni transcription factor LCR-F1 0.0017 0.0015 0.0044
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0077 0.0464 0.1375
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0551
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0551
Brugia malayi hypothetical protein 0.0063 0.036 0.0551
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0061 0.0344 0.1029
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0099 0.0636 0.2328
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0063 0.036 0.1074
Echinococcus granulosus rhodopsin orphan GPCR 0.0063 0.036 0.0471
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0099 0.0636 0.0854
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0027 0.0091 0.014
Mycobacterium ulcerans hypothetical protein 0.0099 0.0636 0.2328
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0027 0.0091 0.0273
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0061 0.0344 0.0344
Brugia malayi Carboxylesterase family protein 0.0178 0.1228 0.188
Schistosoma mansoni opsin-like receptor 0.0063 0.036 0.1074
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0551
Plasmodium vivax amine transporter, putative 0.0018 0.0019 0.0056
Brugia malayi hypothetical protein 0.0063 0.036 0.0551
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0063 0.036 0.0471
Echinococcus multilocularis jun protein 0.0041 0.019 0.0249
Schistosoma mansoni ran 0.0021 0.004 0.0118
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0063 0.036 0.1074
Trypanosoma brucei heat shock protein, putative 0.0016 0.0004 0.0004
Echinococcus granulosus acetylcholinesterase 0.0178 0.1228 0.1609
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1126 0.8398 0.8398
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0099 0.0636 0.2328
Onchocerca volvulus 0.0126 0.0837 0.1123
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0027 0.0091 0.012
Leishmania major cytochrome p450-like protein 0.0032 0.0122 0.0122
Onchocerca volvulus Netrin receptor homolog 0.0029 0.0101 0.0136
Toxoplasma gondii hypothetical protein 0.0018 0.0019 0.0056
Loa Loa (eye worm) hypothetical protein 0.003 0.0111 0.0169
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0017 0.0013 0.0018
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0984 0.7326 0.7326
Echinococcus granulosus G protein coupled receptor 139 0.0063 0.036 0.0471
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0099 0.0636 0.0854
Giardia lamblia DNA topoisomerase II 0.0308 0.2217 0.8152
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0082 0.0507 0.1852
Echinococcus multilocularis glutamate synthase 0.0099 0.0636 0.0833
Schistosoma mansoni biogenic amine (5HT) receptor 0.0063 0.036 0.1074
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0029
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0551
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0096 0.0096
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0032 0.0122 0.0353
Echinococcus multilocularis geminin 0.0301 0.216 0.2831
Echinococcus granulosus tm gpcr rhodopsin 0.1024 0.7632 1
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0099 0.0636 0.0636
Echinococcus multilocularis Ankyrin 0.0016 0.0006 0.0008
Schistosoma mansoni thyroid hormone receptor 0.0027 0.0091 0.0273
Leishmania major heat shock protein 83-1 0.0016 0.0004 0.0004
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0021 0.0039 0.0117
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0016 0.0004 0.0005
Trypanosoma cruzi trypanothione reductase, putative 0.0458 0.3348 0.3348
Brugia malayi MH2 domain containing protein 0.0093 0.0588 0.0901
Loa Loa (eye worm) hypothetical protein 0.0159 0.109 0.1669
Loa Loa (eye worm) hypothetical protein 0.0063 0.036 0.0551
Echinococcus granulosus netrin receptor unc 5 0.002 0.0038 0.005
Onchocerca volvulus Neuropeptide F receptor homolog 0.0063 0.036 0.0483
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0021 0.0039 0.0051
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0984 0.7326 0.7326

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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