Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | carboxylesterase 5A | 0.0147 | 0.3013 | 0.3013 |
Loa Loa (eye worm) | hypothetical protein | 0.0172 | 0.3632 | 0.6054 |
Echinococcus multilocularis | acetylcholinesterase | 0.0147 | 0.3013 | 0.3013 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0147 | 0.3013 | 1 |
Brugia malayi | ecdysteroid receptor | 0.0172 | 0.3632 | 0.6054 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0025 | 0.0059 | 0.0197 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0059 | 0.0099 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0077 | 0.1323 | 1 |
Schistosoma mansoni | acetylcholinesterase | 0.0025 | 0.0059 | 0.0197 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0025 | 0.0059 | 0.0059 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0025 | 0.0059 | 0.0197 |
Loa Loa (eye worm) | hypothetical protein | 0.0147 | 0.3013 | 0.5022 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0025 | 0.0059 | 0.0059 |
Echinococcus multilocularis | expressed protein | 0.0436 | 1 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.0025 | 0.0059 | 0.0099 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0077 | 0.1323 | 0.1323 |
Echinococcus multilocularis | neuroligin | 0.0025 | 0.0059 | 0.0059 |
Schistosoma mansoni | gliotactin | 0.0025 | 0.0059 | 0.0197 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0077 | 0.1323 | 0.2205 |
Echinococcus granulosus | acetylcholinesterase | 0.0147 | 0.3013 | 0.3013 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0025 | 0.0059 | 0.0059 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0025 | 0.0059 | 0.0059 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0147 | 0.3013 | 0.3013 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0077 | 0.1323 | 0.5 |
Echinococcus granulosus | transcription factor Dp 1 | 0.0045 | 0.0538 | 0.0538 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0025 | 0.0059 | 0.0197 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0025 | 0.0059 | 0.5 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0025 | 0.0059 | 0.0197 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0025 | 0.0059 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0025 | 0.0059 | 0.0099 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.027 | 0.6 | 1 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0172 | 0.3632 | 1 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0025 | 0.0059 | 0.5 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0025 | 0.0059 | 0.0059 |
Brugia malayi | Carboxylesterase family protein | 0.0025 | 0.0059 | 0.0099 |
Brugia malayi | follicle stimulating hormone receptor | 0.027 | 0.6 | 1 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0077 | 0.1323 | 0.2205 |
Echinococcus granulosus | acetylcholinesterase | 0.0147 | 0.3013 | 0.3013 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0059 | 0.0099 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0025 | 0.0059 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0059 | 0.0099 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0059 | 0.0099 |
Loa Loa (eye worm) | hypothetical protein | 0.0147 | 0.3013 | 0.5022 |
Loa Loa (eye worm) | carboxylesterase | 0.0147 | 0.3013 | 0.5022 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0077 | 0.1323 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.0147 | 0.3013 | 0.5022 |
Echinococcus granulosus | neuroligin | 0.0025 | 0.0059 | 0.0059 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0147 | 0.3013 | 0.5022 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0025 | 0.0059 | 0.0059 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0077 | 0.1323 | 0.439 |
Loa Loa (eye worm) | carboxylesterase | 0.0025 | 0.0059 | 0.0099 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0059 | 0.0099 |
Echinococcus multilocularis | acetylcholinesterase | 0.0147 | 0.3013 | 0.3013 |
Brugia malayi | Carboxylesterase family protein | 0.0025 | 0.0059 | 0.0099 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0059 | 0.0099 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0059 | 0.0099 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0077 | 0.1323 | 0.1323 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0077 | 0.1323 | 0.5 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0025 | 0.0059 | 0.0197 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0077 | 0.1323 | 0.5 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0025 | 0.0059 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0059 | 0.0099 |
Brugia malayi | Carboxylesterase family protein | 0.0025 | 0.0059 | 0.0099 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0025 | 0.0059 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.0147 | 0.3013 | 0.5022 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.0045 | 0.0538 | 0.0538 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.